Details of the Drug

General Information of Drug (ID: DMLKI2B)

Drug Name

Trafermin

Synonyms

Fiblast; Fiblast (TN); Trafermin (genetical recombination); Trafermin (USAN/INN); Trafermin (genetical recombination) (JAN)

Indication

Disease Entry	ICD 11	Status	REF
Periodontitis	DA0C	Phase 3	[1]
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ATC Code

D03AX15: Trafermin

D03AX: Other cicatrizants

D03A: CICATRIZANTS

D03: PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS

D: DERMATOLOGICALS

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fibroblast growth factor receptor 2 (FGFR2)	TTGJVQM	FGFR2_HUMAN	Activator	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Periodontitis

ICD Disease Classification

DA0C

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fibroblast growth factor receptor 2 (FGFR2)	DTT	FGFR2	4.82E-01	-0.03	-0.2

Molecular Expression Atlas (MEA)

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References

1	Emerging drugs for diabetic foot ulcers. Expert Opin Emerg Drugs. 2006 Nov;11(4):709-24.