Details of the Drug

General Information of Drug (ID: DMLKK6Q)

Drug Name
bromosporine
Synonyms
Bromosporine; 1619994-69-2; Bromorsporine; Bioomosporine; GTPL8234; SCHEMBL17359131; CHEMBL3133807; C17H20N6O4S; Bromosporine, > AOB6807; MolPort-035-395-798; HMS3653C21; KS-00000T5O; ZINC95616589; 2286AH; s7233; AKOS024458332; CS-3240; NCGC00351471-11; QC-10870; HY-15815; AK175193; A4186; SW219727-1; J3.656.836D; N-[(6-3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate; ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
Chemical Identifiers
Formula
C17H20N6O4S
Canonical SMILES
CCOC(=O)NC1=CC(=NN2C1=NN=C2C)C3=CC(=C(C=C3)C)NS(=O)(=O)C
InChI
1S/C17H20N6O4S/c1-5-27-17(24)18-15-9-14(21-23-11(3)19-20-16(15)23)12-7-6-10(2)13(8-12)22-28(4,25)26/h6-9,22H,5H2,1-4H3,(H,18,24)
InChIKey
UYBRROMMFMPJAN-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
72943187
TTD ID
D07ALG

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 3.4915 5.5284 0.3264 0.6124
EW-3 GDSC2 1.2306 4.953 -0.7877 10.6248
NOS-1 [Human HNSCC] GDSC2 1.6649 5.2609 -0.6049 8.3598
CADO-ES1 GDSC2 1.7443 8.589 -2.1934 17.1675
HuO9 GDSC2 1.7702 4.6443 -0.227 5.7913
CAL-78 GDSC2 1.8677 5.9245 -0.7819 8.9434
TC-71 GDSC2 1.9158 8.5977 -2.0652 16.062
ES8 GDSC2 2.0484 5.3229 -0.3625 6.0035
HOS GDSC2 2.0505 5.5539 -0.4721 6.6571
ES5 GDSC2 2.103 4.9511 -0.1493 4.6228
CAL-72 GDSC2 2.3126 7.1175 -1.0459 9.4724
SK-PN-DW GDSC2 2.3208 11.0806 -2.9863 19.3583
H-EMC-SS GDSC2 2.3971 6.2888 -0.5903 6.629
G-292 clone A141B1 GDSC2 2.4041 13.8651 -4.3031 24.1017
SK-ES-1 GDSC2 2.5551 4.1125 0.4703 0.7517
EW-24 GDSC2 2.6585 4.6732 0.2922 1.3963
A-673 GDSC2 2.7226 10.537 -2.4202 15.821
HuO-3N1 GDSC2 2.7318 8.9096 -1.621 11.7482
EW-18 GDSC2 2.8055 4.8453 0.2924 1.2452
U2OS GDSC2 2.8137 11.9231 -3.0336 18.3649
MG-63 GDSC2 3.0166 14.7906 -4.2953 22.6404
EW-11 GDSC2 3.0421 9.326 -1.6086 11.0101
EW-13 GDSC2 3.0694 4.8288 0.4153 0.5845
SaOS-2 GDSC2 3.1841 12.4435 -3.0194 17.4552
ES4 GDSC2 3.2802 11.2082 -2.3514 14.2393
EW-16 GDSC2 3.3352 13.9483 -3.6462 19.6273
CHSA8926 GDSC2 3.4252 15.1261 -4.1579 21.2692
NY GDSC2 3.4656 16.9575 -5.0287 23.9298
EW-1 GDSC2 3.5031 6.0799 0.1197 1.3158
EW-7 GDSC2 3.5428 12.7985 -2.938 16.3227
ES6 GDSC2 3.56 5.7413 0.2749 0.7285
ES7 GDSC2 3.9526 6.4756 0.161 0.8485
MHH-ES-1 GDSC2 4.1516 13.3795 -2.8012 14.4836
EW-22 GDSC2 4.5943 6.4946 0.3937 0.135
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 1.8224 4.8166 -0.2739 5.9604
OACP4 C GDSC2 1.9191 7.3893 -1.4647 12.815
OACM5.1 C GDSC2 2.1646 9.8128 -2.4775 17.4563
KYSE-50 GDSC2 2.6518 5.1528 0.0849 2.4042
ESO-26 GDSC2 2.995 14.987 -4.4085 23.0603
KYAE-1 GDSC2 3.1141 4.7558 0.4604 0.4301
SK-GT-4 GDSC2 3.3614 11.977 -2.6668 15.522
FLO-1 GDSC2 3.7194 8.017 -0.5853 4.3341
ESO-51 GDSC2 3.7537 5.5877 0.4062 0.3036
TE-12 GDSC2 3.8137 15.5328 -4.0759 20.1563
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 1.8394 7.6134 -1.6359 13.9738
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC2 -0.3781 5.3653 -2.4158 25.0338
TGW GDSC2 1.0336 4.0451 -0.4946 9.3565
CHP-212 GDSC2 1.0441 5.667 -1.2969 14.2342
NB(TU)1 GDSC2 1.1977 2.7791 0.2694 4.0822
SJNB-13 GDSC2 1.5953 5.6544 -0.8516 10.0417
CHP-134 GDSC2 1.8259 5.7215 -0.7128 8.6265
KP-N-YN GDSC2 2.0576 10.4783 -2.8892 19.6074
NH-12 GDSC2 2.1262 4.171 0.2256 2.4369
SJNB-10 GDSC2 2.2139 7.5024 -1.3034 11.18
GI-ME-N GDSC2 2.2573 4.8904 -0.024 3.6101
SK-N-DZ GDSC2 2.3048 3.5073 0.596 0.4842
SJNB-7 GDSC2 2.5653 8.7431 -1.6573 12.319
Kelly GDSC2 2.6005 4.0774 0.5037 0.5963
SK-N-BE(2)-M17 GDSC2 2.97 4.7573 0.4008 0.6943
IMR-5 GDSC2 3.0321 4.9098 0.3689 0.7606
SJNB-14 GDSC2 3.16 4.7454 0.482 0.3541
SiMa GDSC2 3.1792 5.8521 0.0594 1.882
GOTO GDSC2 3.4038 5.619 0.2557 0.8919
SK-N-AS GDSC2 5.518 18.3623 -4.2661 17.5386
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 2.9553 4.8649 0.353 0.874
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC2 -0.4073 1.6693 -0.7592 16.0504
MDA-MB-453 GDSC2 0.1296 8.4156 -3.456 27.6004
Hs 578T GDSC2 0.7452 4.4326 -0.933 12.949
DU4475 GDSC2 1.3285 5.267 -0.8662 10.8373
HCC1569 GDSC2 1.488 6.1846 -1.1977 12.3983
Evsa-T GDSC2 1.6297 4.5484 -0.2807 6.4467
BT-549 GDSC2 1.636 6.5193 -1.2492 12.3074
HCC1937 GDSC2 1.6449 4.8505 -0.4178 7.2565
HDQ-P1 GDSC2 1.814 3.9633 0.1294 3.5462
MDA-MB-157 GDSC2 1.8326 7.684 -1.6761 14.2124
BT-474 GDSC2 1.9845 7.9671 -1.701 13.9579
MDA-MB-468 GDSC2 2.0003 6.0544 -0.7499 8.4388
HCC1500 GDSC2 2.0305 5.4011 -0.4122 6.3402
CAL-85-1 GDSC2 2.1193 7.1348 -1.192 10.7658
MDA-MB-231 GDSC2 2.158 4.3882 0.146 2.8244
CAL-120 GDSC2 2.2667 10.9568 -2.9662 19.4075
MDA-MB-361 GDSC2 2.2955 7.6588 -1.3212 11.0893
OCUB-M GDSC2 2.3025 6.1506 -0.5874 6.8065
MDA-MB-330 GDSC2 2.4092 15.4601 -5.0918 26.4698
HCC1428 GDSC2 2.5148 6.0613 -0.4072 5.335
EFM-192A GDSC2 2.5925 5.6265 -0.1594 3.7973
HCC38 GDSC2 2.6141 6.8151 -0.6975 6.8163
MDA-MB-436 GDSC2 2.6247 4.8854 0.1859 1.9354
HCC1419 GDSC2 2.6406 12.571 -3.4817 20.5967
COLO 824 GDSC2 2.6916 6.1461 -0.3373 4.6193
HCC1806 GDSC2 2.7158 6.9716 -0.7056 6.6641
MFM-223 GDSC2 2.7451 9.5087 -1.9023 13.1994
BT-20 GDSC2 2.7593 7.2137 -0.7916 7.0696
T-47D GDSC2 2.9327 7.1194 -0.6382 5.8794
MRK-nu-1 GDSC2 3.0046 4.3835 0.5523 0.2531
MCF-7 GDSC2 3.1285 20.7165 -7.1454 29.6854
CAMA-1 GDSC2 3.2348 13.7561 -3.625 19.7702
CAL-51 GDSC2 3.2553 11.1763 -2.3533 14.3017
HCC1954 GDSC2 3.2621 4.9437 0.4499 0.3896
HCC1187 GDSC2 3.3548 5.0314 0.4539 0.342
MDA-MB-415 GDSC2 3.411 5.5712 0.2771 0.8149
HCC1143 GDSC2 3.4648 6.1832 0.0608 1.5869
JIMT-1 GDSC2 3.4915 4.9476 0.533 0.1531
HCC70 GDSC2 3.5078 5.2429 0.4363 0.3242
ZR-75-30 GDSC2 3.9508 16.4796 -4.4397 21.0992
AU565 GDSC2 4.2342 8.8585 -0.6737 4.0743
EFM-19 GDSC2 4.5268 6.6962 0.3019 0.2746
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC2 0.8256 2.7961 -0.0472 7.1555
KS-1 [Human Krukenberg tumour] GDSC2 0.8862 3.8094 -0.5006 9.8289
D283 Med GDSC2 1.0506 2.4324 0.3255 4.1257
CAS-1 GDSC2 1.1417 3.108 0.0616 5.5418
M059J GDSC2 1.3124 4.1896 -0.3425 7.6291
AM-38 GDSC2 1.4169 12.3232 -4.3181 26.6784
T98G GDSC2 1.6701 3.8359 0.0942 4.0547
H4 GDSC2 1.6799 10.3989 -3.1456 21.7025
42-MG-BA GDSC2 1.6857 7.4288 -1.6623 14.5233
LN-18 GDSC2 1.7028 12.5342 -4.1924 25.5097
U-87MG ATCC GDSC2 1.7862 6.4434 -1.0975 11.0295
LN-229 GDSC2 1.8138 10.0704 -2.8761 20.1928
A-172 GDSC2 1.8376 4.6513 -0.1835 5.377
LN-405 GDSC2 1.8822 5.8147 -0.7176 8.5211
PFSK-1 GDSC2 1.952 9.6987 -2.5837 18.5042
Daoy GDSC2 2.1216 5.9053 -0.5926 7.2238
D-392MG GDSC2 2.3621 11.2935 -3.0604 19.5705
Becker GDSC2 2.411 5.312 -0.1244 3.9093
U-118MG GDSC2 2.4353 4.3891 0.2993 1.6198
U-251MG GDSC2 2.4923 4.8892 0.1131 2.4829
KINGS-1 GDSC2 2.4968 9.1006 -1.8807 13.6626
ONS-76 GDSC2 2.5835 5.1926 0.0299 2.7868
GaMG GDSC2 2.5958 8.4292 -1.4834 11.3056
D-263MG GDSC2 2.6317 11.7015 -3.0592 18.906
SW1088 GDSC2 2.6453 12.7889 -3.5858 20.9856
DK-MG GDSC2 2.8853 10.6676 -2.3669 15.1906
YH-13 GDSC2 3.181 11.915 -2.7639 16.3527
SF539 GDSC2 3.1963 11.1384 -2.376 14.5382
GB-1 GDSC2 3.4094 5.263 0.3914 0.4731
DBTRG-05MG GDSC2 3.7471 5.5038 0.4331 0.2542
SK-MG-1 GDSC2 3.7975 5.8944 0.3134 0.4975
SF268 GDSC2 4.1413 6.6189 0.1841 0.6772
KALS-1 GDSC2 5.5177 19.3539 -4.7397 19.0766
8-MG-BA GDSC2 5.9929 21.1852 -5.2959 19.9207
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 2.0943 9.0399 -2.1484 16.0252
ETK-1 GDSC2 2.8767 5.8354 -0.0908 2.9931
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC2 1.9615 5.539 -0.5267 7.1831
KLE GDSC2 2.0019 11.834 -3.6063 22.6654
MFE-319 GDSC2 2.4162 4.8056 0.1076 2.6243
MFE-280 GDSC2 2.4592 5.742 -0.2934 4.7847
RL95-2 GDSC2 2.9406 11.6171 -2.7909 17.0172
MFE-296 GDSC2 3.8139 7.1421 -0.1637 2.2005
AN3-CA GDSC2 3.9703 7.4801 -0.227 2.3156
EN GDSC2 4.9807 17.6553 -4.2891 18.5875
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 128 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCI-AML-3 GDSC2 -1.3851 4.9658 -3.2041 32.4405
L-1236 GDSC2 -1.1049 3.391 -2.2085 26.962
Kasumi-1 GDSC2 -0.9153 1.6098 -1.2835 21.2046
LAMA-84 GDSC2 -0.8137 5.5078 -2.8995 28.873
A4/Fukuda GDSC2 -0.7416 2.6952 -1.5314 21.8534
KMS-12-BM GDSC2 -0.6726 1.4053 -0.9502 18.2778
ST486 GDSC2 -0.6227 1.092 -0.7969 17.2067
WSU-NHL GDSC2 -0.6185 1.4996 -0.9242 17.8954
NCI-H929 GDSC2 -0.6103 6.8108 -3.3366 29.7848
H9 GDSC2 -0.5789 0.6743 -0.6463 16.1925
A3/Kawakami GDSC2 -0.4947 0.8476 -0.5923 15.5085
MEG-01 GDSC2 -0.4823 1.9688 -0.9564 17.4993
BC-1 GDSC2 -0.4035 1.7739 -0.7955 16.2422
Namalwa GDSC2 -0.2805 5.5843 -2.4306 24.7393
VL51 GDSC2 -0.2701 2.4783 -0.9518 16.6145
MOLM-13 GDSC2 -0.2594 1.5023 -0.5382 14.158
OCI-AML-2 GDSC2 -0.2439 0.8798 -0.3267 12.9146
DEL GDSC2 -0.2346 0.9364 -0.3306 12.8926
OPM-2 GDSC2 -0.2141 1.3698 -0.4417 13.4155
L-540 GDSC2 -0.1637 9.5024 -4.2561 31.2239
Jiyoye GDSC2 -0.1437 3.4269 -1.2614 17.9596
ML-2 GDSC2 -0.0537 6.2038 -2.5249 24.3584
NALM-6 GDSC2 0.0341 3.0931 -0.9304 15.3328
SU-DHL-6 GDSC2 0.0931 2.0865 -0.4073 11.9534
SU-DHL-10 GDSC2 0.1239 1.7636 -0.2354 10.8093
GDM-1 GDSC2 0.1312 3.7491 -1.1521 16.3157
BL-41 GDSC2 0.1969 2.6536 -0.5642 12.5127
JVM-3 GDSC2 0.2116 7.285 -2.8215 24.7742
MOLT-13 GDSC2 0.2786 2.7868 -0.5481 12.1188
HAL-01 GDSC2 0.2927 3.6229 -0.9392 14.4677
SU-DHL-5 GDSC2 0.3018 1.6777 -0.014 8.7884
EoL-1 GDSC2 0.3231 1.7458 -0.0217 8.7501
KOPN-8 GDSC2 0.3267 6.3866 -2.2731 21.8309
AMO1 GDSC2 0.4096 2.2021 -0.1435 9.1612
MHH-CALL-2 GDSC2 0.419 3.6044 -0.8133 13.2674
RPMI-8226 GDSC2 0.4377 4.9707 -1.4715 17.1473
697 GDSC2 0.5922 2.5413 -0.1322 8.4493
Loucy GDSC2 0.6416 4.1229 -0.8693 12.8832
SR GDSC2 0.6937 3.4711 -0.4993 10.4166
SCC-3 GDSC2 0.7017 2.9837 -0.2503 8.8274
SUP-B15 GDSC2 0.7123 4.2922 -0.8916 12.7974
HL-60 GDSC2 0.7391 3.9948 -0.72 11.6518
Ku812 GDSC2 0.742 2.1857 0.1805 5.9912
Karpas-422 GDSC2 0.7568 3.7476 -0.5814 10.732
DoHH2 GDSC2 0.7936 2.6784 -0.0169 7.0648
LC4-1 GDSC2 0.8537 2.5832 0.0834 6.2428
MLMA GDSC2 0.8543 3.9314 -0.5888 10.4786
Karpas-45 GDSC2 0.8945 3.6799 -0.4288 9.3525
JVM-2 GDSC2 0.9199 7.6355 -2.3848 20.4795
GA-10 GDSC2 0.9519 4.1712 -0.6259 10.4181
ALL-PO GDSC2 0.9614 4.2796 -0.6721 10.678
P32/ISH GDSC2 0.9898 3.2071 -0.112 7.0697
Daudi GDSC2 1.0019 3.6725 -0.3347 8.4414
KY821 GDSC2 1.0103 3.6694 -0.3261 8.3631
JSC-1 GDSC2 1.0175 2.9547 0.0372 6.0449
P30/OHK GDSC2 1.0273 4.2055 -0.58 9.9103
NOMO-1 GDSC2 1.0348 4.7913 -0.8667 11.6688
Karpas-299 GDSC2 1.0552 4.7645 -0.8364 11.4227
MN-60 GDSC2 1.0633 3.6527 -0.274 7.8815
SKM-1 GDSC2 1.0668 3.3683 -0.129 6.9558
RPMI-6666 GDSC2 1.0686 15.5976 -6.2417 32.4955
DB GDSC2 1.09 8.49 -2.6703 21.3125
BALL-1 GDSC2 1.091 7.9579 -2.4034 20.0541
KE-37 GDSC2 1.1221 3.351 -0.0754 6.4617
SUP-T1 GDSC2 1.1418 4.8829 -0.8246 11.1016
VAL GDSC2 1.145 14.9382 -5.8487 31.468
Karpas-620 GDSC2 1.1582 6.8539 -1.7962 16.7308
Karpas-1106P GDSC2 1.1618 3.5014 -0.1185 6.6246
GR-ST GDSC2 1.1746 6.1815 -1.4467 14.7254
MOLP-8 GDSC2 1.1848 3.7476 -0.223 7.2207
JJN-3 GDSC2 1.1888 3.4789 -0.0858 6.3447
HEL GDSC2 1.1919 2.7993 0.2549 4.1884
IM-9 GDSC2 1.2299 2.7595 0.3037 3.7835
P12-Ichikawa GDSC2 1.2407 8.863 -2.7328 21.1534
JURL-MK1 GDSC2 1.245 2.9851 0.2035 4.3745
EM-2 GDSC2 1.2627 3.2702 0.0757 5.1317
MM1.S GDSC2 1.2664 5.5323 -1.0481 12.1136
PF-382 GDSC2 1.2702 4.2417 -0.4016 8.1122
OCI-M1 GDSC2 1.2838 2.6243 0.4105 2.9836
RPMI-8866 GDSC2 1.3237 5.2516 -0.8624 10.827
MOLT-4 GDSC2 1.3445 6.1433 -1.2905 13.3371
Jurkat GDSC2 1.3634 3.5339 0.0217 5.2144
CA46 GDSC2 1.427 3.557 0.0576 4.834
LP-1 GDSC2 1.4293 3.8357 -0.0779 5.6727
DG-75 GDSC2 1.4438 3.406 0.1438 4.2588
SUP-HD1 GDSC2 1.462 11.2133 -3.7269 24.5533
RC-K8 GDSC2 1.4951 3.3811 0.1926 3.8395
ARH-77 GDSC2 1.5094 3.9313 -0.0658 5.4028
U-698-M GDSC2 1.5152 3.2281 0.2806 3.2568
BE-13 GDSC2 1.5551 9.9251 -3.0088 21.4712
OCI-AML-5 GDSC2 1.5657 3.8548 0.0122 4.7887
EJM GDSC2 1.6147 4.2919 -0.1661 5.7741
CESS GDSC2 1.6661 4.1461 -0.0585 4.9943
Farage GDSC2 1.6938 3.5478 0.2475 3.0842
CCRF-CEM GDSC2 1.7551 14.7153 -5.239 28.4514
KCL-22 GDSC2 1.772 4.883 -0.3418 6.4894
RS4;11 GDSC2 1.8192 4.7952 -0.2659 5.9186
ME1 GDSC2 1.8257 9.2843 -2.4757 18.3306
KMOE-2 GDSC2 1.8806 4.6387 -0.148 5.0699
U266B1 GDSC2 1.8855 7.9018 -1.7436 14.4433
MOLT-16 GDSC2 1.896 8.642 -2.1024 16.3035
SU-DHL-8 GDSC2 1.9007 5.7795 -0.687 8.2924
L-363 GDSC2 1.9395 17.3411 -6.4014 30.7313
KG-1 GDSC2 1.9732 5.2805 -0.3935 6.3524
CML-T1 GDSC2 1.9939 7.286 -1.358 12.0229
CTV-1 GDSC2 2.0012 16.6974 -6.0308 29.7837
Reh GDSC2 2.0375 6.2678 -0.8273 8.8158
Ramos.2G6.4C10 GDSC2 2.0378 6.5207 -0.9505 9.5466
ALL-SIL GDSC2 2.1913 3.9647 0.3532 1.6672
EB2 GDSC2 2.2277 4.364 0.1974 2.4306
Granta-519 GDSC2 2.267 4.1491 0.3139 1.7643
SK-MM-2 GDSC2 2.2739 6.8534 -0.945 8.9724
HH [Human lymphoma] GDSC2 2.3147 6.0491 -0.5309 6.4485
K-562 GDSC2 2.3281 8.5758 -1.7461 13.3529
WIL2 NS GDSC2 2.4001 4.62 0.1806 2.2634
Raji GDSC2 2.4616 3.7847 0.5566 0.5113
ATN-1 GDSC2 2.5077 4.2735 0.3836 1.1496
HC-1 GDSC2 2.6407 10.7175 -2.5685 16.711
Karpas-231 GDSC2 2.6745 3.9572 0.579 0.3236
HDLM-2 GDSC2 2.6773 6.3168 -0.4246 5.1362
SUP-M2 GDSC2 2.7366 3.9311 0.6121 0.2192
TUR GDSC2 2.7476 7.4308 -0.9016 7.7185
TK [Human B-cell lymphoma] GDSC2 2.7717 4.438 0.4386 0.7023
Hs 445 GDSC2 2.8484 4.2874 0.5268 0.3797
L-428 GDSC2 3.105 11.3588 -2.5472 15.5413
DND-41 GDSC2 3.3325 11.9043 -2.6519 15.5176
MHH-PREB-1 GDSC2 3.3756 4.788 0.5465 0.1582
KM-H2 GDSC2 3.6533 5.3031 0.4687 0.2168
⏷ Show the Full List of 128 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 GDSC2 1.0117 8.6405 -2.8105 22.1773
TK-10 GDSC2 1.4707 5.8227 -1.0312 11.4534
KMRC-20 GDSC2 1.7272 10.1644 -2.9912 20.9242
KTCTL-195 GDSC2 1.7458 4.1123 0.013 4.3842
RCC10RGB GDSC2 1.8102 3.3958 0.391 2.0401
A-704 GDSC2 1.8903 5.3812 -0.5002 7.1844
VMRC-RCZ GDSC2 1.8912 4.208 0.0641 3.7801
786-O GDSC2 1.9447 4.2542 0.0767 3.6017
769-P GDSC2 2.037 6.8496 -1.112 10.4981
A-498 GDSC2 2.0646 11.115 -3.1999 20.9062
BFTC-909 GDSC2 2.2315 9.2032 -2.126 15.5663
SW13 GDSC2 2.3061 4.9119 -0.0044 3.4147
NCC010 GDSC2 2.3753 4.9769 0.0071 3.2347
HA7-RCC GDSC2 2.5784 7.029 -0.8223 7.6072
LB996-RCC GDSC2 2.8899 5.4295 0.0913 2.0652
ACHN GDSC2 3.1161 5.2848 0.2597 1.0976
RXF 393L GDSC2 3.211 8.8737 -1.282 8.9142
SN12C GDSC2 3.2434 18.2696 -5.8439 26.588
OS-RC-2 GDSC2 3.2437 4.9989 0.4226 0.4693
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RKO GDSC2 1.0311 4.3908 -0.6695 10.4581
HT-29 GDSC2 1.142 4.1925 -0.4795 8.953
SW626 GDSC2 1.2812 7.1371 -1.8375 16.5985
LS513 GDSC2 1.416 3.2559 0.1971 3.9942
HT-55 GDSC2 1.4911 4.9838 -0.5989 8.7602
LoVo GDSC2 1.498 4.488 -0.3484 7.1883
RCM-1 [Human ESC] GDSC2 1.5538 3.3686 0.2394 3.4236
CCK-81 GDSC2 1.6185 4.0735 -0.0568 5.0916
SW48 GDSC2 1.6321 4.4304 -0.2212 6.0736
NCI-H747 GDSC2 1.6733 4.0584 -0.0109 4.6872
LS123 GDSC2 1.744 8.4445 -2.1219 16.8062
HCT 15 GDSC2 1.7802 7.1166 -1.4349 13.0013
LS411N GDSC2 1.7809 3.9424 0.1176 3.6824
KM12 GDSC2 1.7825 8.6459 -2.192 17.0577
SNU-C1 GDSC2 1.9011 4.3064 0.024 3.9978
NCI-H716 GDSC2 1.9055 4.2242 0.0656 3.7427
SNU-61 GDSC2 1.9406 5.8776 -0.7062 8.3151
COLO205 GDSC2 1.9589 3.617 0.3778 1.8733
CaR-1 GDSC2 2.0187 4.4197 0.0462 3.6398
SNU-C5 GDSC2 2.1073 7.7333 -1.4943 12.5126
GP5d GDSC2 2.1193 6.2571 -0.7642 8.253
HCC2998 GDSC2 2.1507 7.235 -1.2183 10.8426
SW1417 GDSC2 2.1777 6.0986 -0.6471 7.4262
SW1116 GDSC2 2.1783 5.4872 -0.3539 5.6814
C2BBe1 GDSC2 2.25 8.8275 -1.9272 14.5001
DiFi GDSC2 2.2912 5.6738 -0.3683 5.5398
LS180 GDSC2 2.3431 4.0025 0.4153 1.1827
SNU-175 GDSC2 2.345 6.6017 -0.7747 7.8188
CW-2 GDSC2 2.4007 4.9841 0.0187 3.1296
CL-11 GDSC2 2.4512 8.4398 -1.5908 12.2229
SNU-407 GDSC2 2.452 5.9009 -0.3719 5.25
SNU-81 GDSC2 2.5051 4.472 0.2999 1.5332
HCT 116 GDSC2 2.5138 4.6687 0.2207 1.9056
HT115 GDSC2 2.6901 4.4602 0.3936 0.9359
LS1034 GDSC2 2.8103 4.3093 0.5035 0.4657
COLO 320HSR GDSC2 2.8504 4.5835 0.4164 0.7237
SNU-1040 GDSC2 2.9083 4.5653 0.4478 0.5798
SW948 GDSC2 2.9778 4.3572 0.5516 0.2642
SW1463 GDSC2 3.0179 4.8409 0.3893 0.701
MDST8 GDSC2 3.048 4.5502 0.5092 0.3349
SNU-C2B GDSC2 3.4215 12.8731 -3.0595 17.0999
COLO 678 GDSC2 3.5079 7.3789 -0.4215 3.8005
SK-CO-1 GDSC2 3.5766 5.4294 0.3959 0.3895
T84 GDSC2 3.7083 5.6839 0.3549 0.4332
SW837 GDSC2 3.969 17.3605 -4.8572 22.3744
SW620 GDSC2 5.8051 16.179 -3.0569 12.5872
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 1.4237 3.3919 0.1361 4.3539
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-1 GDSC2 1.5496 3.9376 -0.0398 5.1463
HLE GDSC2 1.6094 10.5399 -3.2721 22.4111
Hep-G2/C3A GDSC2 1.7794 4.7179 -0.2563 5.9498
Hep 3B2.1-7 GDSC2 1.8518 7.0308 -1.3383 12.2663
JHH-6 GDSC2 1.9131 5.8235 -0.6996 8.3393
SNU-398 GDSC2 2.1886 7.6011 -1.37 11.6173
Huh-7 GDSC2 2.1963 4.2798 0.2172 2.3727
SNU-387 GDSC2 2.2676 10.3332 -2.6569 18.0319
JHH-2 GDSC2 2.3625 8.4154 -1.6427 12.7134
JHH-7 GDSC2 2.4893 6.352 -0.5599 6.2669
SK-HEP-1 GDSC2 2.5585 5.7539 -0.2379 4.2924
SNU-423 GDSC2 2.8288 16.0574 -5.0642 25.426
JHH-1 GDSC2 3.3386 4.7084 0.5606 0.1452
SNU-449 GDSC2 4.2584 6.1877 0.3807 0.2128
JHH-4 GDSC2 5.2348 21.251 -5.8502 22.7502
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 129 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H526 GDSC2 -1.3108 2.4714 -2.0343 26.9965
IST-SL2 GDSC2 -0.5662 3.6223 -1.769 22.4563
Ms-1 GDSC2 0.3969 4.3181 -1.1851 15.6002
RERF-LC-KJ GDSC2 0.5659 2.4779 -0.1259 8.4995
NCI-H2227 GDSC2 0.6614 6.0198 -1.7974 18.2533
SBC-3 GDSC2 1.0781 4.4997 -0.6852 10.4203
NCI-H211 GDSC2 1.1551 3.2996 -0.0233 6.0416
EMC-BAC-2 GDSC2 1.2046 3.9762 -0.3212 7.7852
NCI-H524 GDSC2 1.2659 4.0314 -0.3002 7.4874
NCI-H446 GDSC2 1.3019 2.9133 0.2818 3.7414
COR-L105 GDSC2 1.3289 9.8981 -3.178 22.813
NCI-H810 GDSC2 1.4004 5.2343 -0.7934 10.1972
NCI-H2810 GDSC2 1.4186 5.2912 -0.8075 10.2345
NCI-H2804 GDSC2 1.4549 3.9879 -0.1339 5.9587
EBC-1 GDSC2 1.4842 4.3457 -0.2885 6.8494
Calu-3 GDSC2 1.588 8.942 -2.4923 19.0548
Lu-139 GDSC2 1.627 4.4125 -0.2161 6.054
KNS-62 GDSC2 1.6598 10.6127 -3.2682 22.2574
SW1271 GDSC2 1.6663 6.4153 -1.1744 11.7894
NCI-H1915 GDSC2 1.686 5.0758 -0.4983 7.6532
Lu-65 GDSC2 1.6934 4.266 -0.0974 5.1714
NCI-H720 GDSC2 1.6991 4.0527 0.0097 4.5052
NCI-H522 GDSC2 1.7263 6.2424 -1.0433 10.8594
NCI-H1869 GDSC2 1.7281 5.3014 -0.5782 8.0417
NCI-H2722 GDSC2 1.7487 4.7444 -0.2909 6.2311
HCC44 GDSC2 1.7755 9.6464 -2.6951 19.4864
NCI-H2135 GDSC2 1.8168 3.3433 0.4188 1.8751
DMS 79 GDSC2 1.8276 5.4608 -0.5839 7.8391
EPLC-272H GDSC2 1.8446 5.3384 -0.512 7.3614
NCI-H345 GDSC2 1.8447 2.6325 0.7349 0.3259
NCI-H2122 GDSC2 1.8638 6.7491 -1.1902 11.3789
NCI-H2023 GDSC2 1.8648 4.3105 -0.0019 4.2252
NCI-H1944 GDSC2 1.8676 6.7722 -1.1988 11.4196
SK-MES-1 GDSC2 1.8793 4.2075 0.0565 3.8482
DMS 114 GDSC2 1.8871 12.9607 -4.2581 25.245
NCI-H82 GDSC2 1.8996 4.5489 -0.0923 4.6945
IA-LM GDSC2 1.9444 8.6076 -2.0483 15.9005
DMS 273 GDSC2 1.9446 7.7577 -1.6275 13.6574
NCI-H2731 GDSC2 1.9448 9.8771 -2.6778 18.9571
NCI-H2029 GDSC2 2.0012 4.1907 0.1417 3.1198
NCI-H1666 GDSC2 2.0109 9.0371 -2.2103 16.5496
SBC-5 GDSC2 2.0288 3.1764 0.6028 0.6843
LCLC-97TM1 GDSC2 2.0373 7.4953 -1.4289 12.3176
HOP-92 GDSC2 2.0495 6.6521 -1.0063 9.848
HCC366 GDSC2 2.059 5.3086 -0.3484 5.8965
COR-L311 GDSC2 2.0673 5.4693 -0.4199 6.3074
LC-1/sq GDSC2 2.0947 10.7788 -3.0098 20.0329
SK-LU-1 GDSC2 2.0965 4.7728 -0.0696 4.1677
NCI-H1975 GDSC2 2.1076 6.0262 -0.6606 7.661
NCI-H1623 GDSC2 2.1201 6.2658 -0.7679 8.2729
NCI-H596 GDSC2 2.1465 4.7482 -0.0266 3.824
NCI-H2369 GDSC2 2.1604 3.996 0.3228 1.8659
NCI-H2869 GDSC2 2.1846 4.4809 0.1196 2.9266
HARA [Human squamous cell lung carcinoma] GDSC2 2.1858 5.4117 -0.3132 5.4253
NCI-H1299 GDSC2 2.1878 11.2526 -3.1732 20.4803
NCI-H2170 GDSC2 2.2095 4.2866 0.2217 2.3282
LXF 289 GDSC2 2.225 9.9875 -2.5182 17.4952
NCI-H1755 GDSC2 2.2415 10.1368 -2.5795 17.7406
NCI-H1581 GDSC2 2.2419 10.4434 -2.7308 18.4323
NCI-H2795 GDSC2 2.247 14.9143 -4.9472 26.4484
NCI-H23 GDSC2 2.3024 11.0334 -2.9769 19.3638
NCI-H661 GDSC2 2.3119 4.413 0.223 2.169
NCI-H2373 GDSC2 2.3394 7.3247 -1.1276 9.8839
NCI-H358 GDSC2 2.3952 5.275 -0.117 3.8949
HOP-62 GDSC2 2.3973 4.7289 0.131 2.5282
NCI-H513 GDSC2 2.4123 8.4084 -1.6033 12.382
NCI-H1155 GDSC2 2.4264 7.123 -0.9698 8.78
NCI-H2087 GDSC2 2.4453 6.6176 -0.7148 7.2574
LOU-NH91 GDSC2 2.5438 9.7526 -2.1659 15.0058
NCI-H1092 GDSC2 2.5689 4.4823 0.3273 1.335
NCI-H1993 GDSC2 2.5954 6.958 -0.7774 7.3139
NCI-H1963 GDSC2 2.6035 4.6869 0.2592 1.6093
Lu-165 GDSC2 2.606 11.3464 -2.9034 18.2993
NCI-H1781 GDSC2 2.6231 5.2529 0.0253 2.7528
NCI-H2461 GDSC2 2.6247 6.0921 -0.3532 4.8263
NCI-H196 GDSC2 2.6438 9.1255 -1.7877 12.8328
NCI-H650 GDSC2 2.6441 11.5904 -2.9953 18.6042
NCI-H1792 GDSC2 2.6457 8.1503 -1.314 10.258
NCI-H1694 GDSC2 2.7463 4.3782 0.4506 0.6783
HCC827 GDSC2 2.7505 5.3641 0.0462 2.4661
HCC15 GDSC2 2.7852 13.2035 -3.6854 21.0287
CPC-N GDSC2 2.8047 4.616 0.3837 0.8783
NCI-H250 GDSC2 2.834 4.9474 0.2644 1.3369
UMC-11 GDSC2 2.8578 5.1487 0.1931 1.6274
PC-14 GDSC2 2.8674 5.4782 0.059 2.2499
VMRC-LCD GDSC2 2.8685 10.7782 -2.4329 15.5429
NCI-H1563 GDSC2 2.8696 12.7921 -3.4197 19.8122
Calu-6 GDSC2 2.8721 9.9058 -2.0056 13.4414
NCI-H3255 GDSC2 2.8972 5.3801 0.116 1.9394
NCI-H1793 GDSC2 2.938 5.0557 0.2695 1.2152
HCC78 GDSC2 2.9787 13.783 -3.8268 21.0995
NCI-H3122 GDSC2 3.004 9.6713 -1.8005 12.0987
COR-L23 GDSC2 3.088 10.119 -1.9585 12.7269
LK-2 GDSC2 3.1652 12.4288 -3.0258 17.5245
NCI-H2141 GDSC2 3.1726 4.6703 0.5136 0.2767
NCI-H1876 GDSC2 3.2111 5.3412 0.2797 0.9468
A-427 GDSC2 3.247 6.0992 -0.0099 2.1232
Lu-135 GDSC2 3.2544 5.138 0.3754 0.5989
DMS 53 GDSC2 3.3028 5.6835 0.1862 1.2262
NCI-H2595 GDSC2 3.3631 7.0798 -0.3697 3.7397
NCI-H2228 GDSC2 3.3872 8.9525 -1.2065 8.1708
SHP-77 GDSC2 3.3915 12.1436 -2.7265 15.724
NCI-H1355 GDSC2 3.4104 12.8329 -3.0478 17.0752
NCI-H209 GDSC2 3.4237 5.4167 0.3405 0.6083
NCI-H2803 GDSC2 3.4288 5.2389 0.4077 0.4225
ABC-1 GDSC2 3.4344 6.4339 -0.0564 2.1268
NCI-H226 GDSC2 3.4392 14.2794 -3.7329 19.7232
COLO 668 GDSC2 3.4471 5.7524 0.223 0.9752
NCI-H2405 GDSC2 3.4781 15.8678 -4.4834 22.2352
NCI-H2818 GDSC2 3.4884 15.4366 -4.2641 21.4921
NCI-H1651 GDSC2 3.515 12.6203 -2.8711 16.0939
SW1573 GDSC2 3.5205 9.2619 -1.267 8.2475
NCI-H2085 GDSC2 3.5296 5.8107 0.2359 0.8735
NCI-H727 GDSC2 3.5879 13.5747 -3.2829 17.6599
NCI-H520 GDSC2 3.5884 19.0327 -5.9606 26.1618
NCI-H1435 GDSC2 3.625 5.1121 0.5239 0.139
NCI-H1048 GDSC2 3.6617 5.0072 0.5716 0.0791
Lu-99A GDSC2 3.6687 6.382 0.0749 1.3507
NCI-H841 GDSC2 3.7284 5.3909 0.4653 0.2035
NCI-H441 GDSC2 3.7434 15.6794 -4.198 20.7245
NCI-H1693 GDSC2 3.8058 5.702 0.3853 0.3291
NCI-H2591 GDSC2 3.8115 16.214 -4.4102 21.2911
EKVX GDSC2 3.8809 6.3815 0.1668 0.874
RERF-LC-Sq1 GDSC2 4.0576 13.5025 -2.9233 15.1947
NCI-H1650 GDSC2 4.2013 6.3675 0.2977 0.3774
NCI-H322M GDSC2 4.544 18.2547 -4.8819 21.3108
NCI-H1568 GDSC2 4.6148 18.1336 -4.7732 20.8416
LCLC-103H GDSC2 5.284 13.4075 -2.1016 9.35
A-549 GDSC2 6.3133 23.0889 -5.9915 21.2799
⏷ Show the Full List of 129 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 1.1774 3.7595 -0.2348 7.3156
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-140 GDSC2 1.2371 3.5937 -0.1049 6.3356
OE19 GDSC2 1.3731 2.9041 0.3381 3.2225
TE-6 GDSC2 1.9995 11.8192 -3.6009 22.6512
OE21 GDSC2 2.0657 9.9224 -2.6072 18.3172
KYSE-270 GDSC2 2.2879 7.4418 -1.2209 10.5362
OE33 GDSC2 2.3323 6.0119 -0.5016 6.2399
COLO 680N GDSC2 2.5958 7.7314 -1.1466 9.4259
TE-8 GDSC2 2.6272 9.6303 -2.0457 14.2053
TE-5 GDSC2 2.7457 10.6688 -2.468 15.9933
TE-15 GDSC2 2.8612 9.77 -1.9474 13.1693
KYSE-520 GDSC2 2.9041 11.2284 -2.6272 16.3641
EC-GI-10 GDSC2 3.3579 4.9542 0.4824 0.2786
TE-9 GDSC2 3.496 4.8829 0.5565 0.1203
KYSE-410 GDSC2 3.5321 11.3035 -2.2249 13.1023
TE-4 GDSC2 3.658 5.4732 0.411 0.3256
KYSE-70 GDSC2 3.9136 11.6514 -2.1373 11.9173
TE-1 GDSC2 5.9766 20.9578 -5.1981 19.6661
KYSE-450 GDSC2 5.9804 17.8337 -3.7167 14.8197
KYSE-510 GDSC2 6.9855 25.5681 -6.7248 22.0159
KYSE-180 GDSC2 7.7621 23.1717 -5.085 16.5343
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DOV13 GDSC2 1.231 3.3618 0.0057 5.6551
A2780 GDSC2 1.2609 4.9401 -0.7571 10.3519
TOV-21G GDSC2 1.55 5.8388 -0.9777 10.922
EFO-21 GDSC2 1.8199 5.3208 -0.5211 7.4742
OV56 GDSC2 1.835 6.316 -0.9983 10.3199
OAW28 GDSC2 1.8363 5.006 -0.356 6.4296
OVCAR-3 GDSC2 1.9518 4.4578 -0.0146 4.1255
EFO-27 GDSC2 1.9522 5.607 -0.5662 7.4431
ES-2 GDSC2 2.0947 3.8164 0.3655 1.7378
TOV-112D GDSC2 2.2426 7.1169 -1.0949 9.916
TYK-nu GDSC2 2.3477 7.4965 -1.2051 10.3091
OVCAR-5 GDSC2 2.5583 10.7508 -2.6455 17.2634
Kuramochi GDSC2 2.6014 12.5367 -3.4942 20.7396
OVCAR-8 GDSC2 2.6103 5.993 -0.3163 4.6434
SK-OV-3 GDSC2 2.6661 9.1261 -1.7722 12.7003
OVISE GDSC2 2.6942 9.7676 -2.0646 14.1448
IGROV-1 GDSC2 2.7849 10.0455 -2.1354 14.2908
OV-90 GDSC2 2.9097 8.3387 -1.2258 9.2097
OVTOKO GDSC2 2.9919 8.2985 -1.1526 8.6384
OVCAR-4 GDSC2 3.4305 5.8283 0.1863 1.1212
OVK18 GDSC2 3.4873 5.0458 0.4978 0.2104
OAW42 GDSC2 5.2343 18.8453 -4.6881 19.4212
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
QGP-1 GDSC2 1.3558 6.6854 -1.5519 14.8089
MIA PaCa-2 GDSC2 1.6925 5.3244 -0.6158 8.3584
HPAC GDSC2 1.8545 7.5195 -1.5779 13.6134
Panc 02.03 GDSC2 1.8798 12.1959 -3.8827 23.9903
HuP-T3 GDSC2 1.908 5.299 -0.4479 6.8264
BxPC-3 GDSC2 1.9789 7.9642 -1.7038 13.9877
KP-4 GDSC2 2.1867 7.1326 -1.1424 10.3199
Panc 08.13 GDSC2 2.2703 9.2571 -2.1236 15.4583
PSN1 GDSC2 2.3787 4.4865 0.2273 2.0523
KP-2 GDSC2 2.4824 13.268 -3.9466 22.7007
PL4 GDSC2 2.5025 4.7321 0.1874 2.0869
HuP-T4 GDSC2 2.5342 5.5191 -0.1451 3.8151
Capan-1 GDSC2 2.7778 5.4996 0.0021 2.6536
Capan-2 GDSC2 2.9279 10.859 -2.4298 15.3925
SU.86.86 GDSC2 2.9725 4.3788 0.5418 0.2881
KP-3 GDSC2 3.2858 6.1505 -0.012 2.0891
PaTu 8902 GDSC2 3.3218 8.3232 -0.9551 6.9302
AsPC-1 GDSC2 3.3773 5.5646 0.2653 0.8773
Panc 10.05 GDSC2 3.5296 14.9603 -4.0007 20.496
DAN-G GDSC2 3.5913 14.3744 -3.6699 19.1587
KP-1N GDSC2 3.7583 5.909 0.2927 0.5697
SUIT-2 GDSC2 3.7785 14.1246 -3.4157 17.7847
PaTu 8988t GDSC2 3.837 15.2635 -3.928 19.5851
HPAF-II GDSC2 3.9401 5.7825 0.4063 0.2488
CFPAC-1 GDSC2 4.0444 5.7752 0.4458 0.164
YAPC GDSC2 4.6068 16.1211 -3.8068 17.6032
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC2 1.1421 6.1516 -1.4584 14.8866
IST-Mes1 GDSC2 1.9639 10.6147 -3.0296 20.4573
NCI-H28 GDSC2 2.0649 9.9465 -2.6197 18.3772
MSTO-211H GDSC2 2.1742 4.3648 0.1662 2.6859
NCI-H2052 GDSC2 3.2257 6.6199 -0.2435 3.2879
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 1.2065 4.8018 -0.7317 10.3455
VCaP GDSC2 1.2333 13.5271 -5.0702 29.3502
22Rv1 GDSC2 2.2782 5.6151 -0.3491 5.4525
DU145 GDSC2 3.5607 5.703 0.2895 0.6835
PC-3 GDSC2 3.7415 10.6343 -1.769 10.4359
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 3.2399 5.323 0.2992 0.8562
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LOX-IMVI GDSC2 0.8518 3.1966 -0.2242 8.1917
UACC-62 GDSC2 1.1312 2.7635 0.2251 4.538
COLO 792 GDSC2 1.3716 3.788 -0.0977 5.9412
SH-4 GDSC2 1.4785 3.5309 0.1078 4.4003
WM1552C GDSC2 1.5407 4.0463 -0.0994 5.5368
A2058 GDSC2 1.5434 8.9204 -2.517 19.2957
IGR-37 GDSC2 1.6353 5.3529 -0.6723 8.8462
WM115 GDSC2 1.7504 4.5311 -0.186 5.5855
G-mel GDSC2 1.7763 3.399 0.3691 2.2214
M14 GDSC2 1.7945 4.7812 -0.2764 6.038
CP66-MEL GDSC2 1.9865 4.154 0.1497 3.1007
UACC-257 GDSC2 1.9888 4.9308 -0.215 5.2445
Mel JuSo GDSC2 2.0341 10.697 -3.016 20.2161
RPMI-7951 GDSC2 2.0622 10.3541 -2.824 19.3089
SK-MEL-2 GDSC2 2.064 8.7312 -2.0187 15.4405
GAK GDSC2 2.0727 4.5245 0.0313 3.6255
COLO 679 GDSC2 2.1586 7.4037 -1.2951 11.2639
WT2-iPS GDSC2 2.2119 8.1838 -1.6388 13.0541
SK-MEL-5 GDSC2 2.6879 4.8233 0.2444 1.5816
CHL-1 GDSC2 2.8412 8.624 -1.4082 10.3563
IGR-1 GDSC2 3.2609 13.2735 -3.3698 18.7221
HMV-II GDSC2 3.2637 9.2922 -1.4453 9.6881
WM793 GDSC2 3.4189 4.983 0.4948 0.2349
COLO 829 GDSC2 3.6621 5.5263 0.3937 0.3616
WM35 GDSC2 4.1582 6.0246 0.401 0.2045
G-361 GDSC2 4.395 17.1789 -4.4645 20.2877
A101D GDSC2 4.4847 15.3393 -3.5146 16.7445
A-375 GDSC2 4.5737 14.279 -2.9496 14.3041
HT-144 GDSC2 5.0867 18.5858 -4.6641 19.6148
SK-MEL-24 GDSC2 5.1984 21.7378 -6.1124 23.4818
WM278 GDSC2 5.5293 23.3803 -6.677 24.255
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 2.7506 13.4136 -3.8151 21.5882
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYM-1 GDSC2 0.5037 6.938 -2.3921 21.8283
SW982 GDSC2 0.6984 6.0336 -1.7724 17.9989
Rh41 GDSC2 0.9595 3.5125 -0.2902 8.285
G-402 GDSC2 0.9901 3.3365 -0.1765 7.4768
SK-UT-1 GDSC2 1.3949 5.3361 -0.8484 10.5484
SW872 GDSC2 1.8004 4.444 -0.1092 5.0071
RD GDSC2 2.0083 4.3973 0.0501 3.6362
SW684 GDSC2 2.1175 7.438 -1.3418 11.6288
GCT GDSC2 2.1596 13.2421 -4.1835 24.3085
G-401 GDSC2 2.1683 7.7948 -1.4797 12.2823
VA-ES-BJ GDSC2 2.3781 10.924 -2.8655 18.6911
HT-1080 GDSC2 2.5489 5.037 0.0794 2.5773
A-204 GDSC2 2.7492 9.7249 -2.0046 13.7144
SK-LMS-1 GDSC2 2.7788 13.6888 -3.9298 21.934
EW-8 GDSC2 2.9557 5.3119 0.1735 1.6101
MES-SA GDSC2 2.9978 11.4794 -2.6825 16.4009
Rh30 GDSC2 3.3973 5.5024 0.2975 0.7568
RKN GDSC2 3.3981 4.7491 0.5676 0.1236
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NUGC-4 GDSC2 0.5614 5.1914 -1.4716 16.7437
MKN1 GDSC2 1.2596 6.4985 -1.5361 14.9919
AGS GDSC2 1.4217 6.9347 -1.6237 15.0277
ECC10 GDSC2 1.7999 5.0496 -0.4031 6.7999
NCI-N87 GDSC2 1.8224 5.8715 -0.7889 9.0952
OCUM-1 GDSC2 1.8634 11.5957 -3.5966 22.9904
MKN45 GDSC2 2.097 14.6578 -4.9376 26.7846
23132/87 GDSC2 2.1079 7.8977 -1.5747 12.9573
IM95 GDSC2 2.222 7.3779 -1.2368 10.7806
NUGC-3 GDSC2 2.2645 5.3037 -0.2115 4.6748
SNU-1 GDSC2 2.2681 4.1545 0.3121 1.7718
KATO III GDSC2 2.4382 5.5384 -0.2121 4.3583
SNU-5 GDSC2 2.5102 11.1455 -2.8757 18.4107
SK-GT-2 GDSC2 2.5838 4.7331 0.2296 1.7737
RERF-GC-1B GDSC2 2.6953 21.1496 -7.6991 31.5699
HGC-27 GDSC2 2.7388 7.0394 -0.7228 6.7177
MKN28 GDSC2 2.7525 9.6861 -1.9833 13.5985
Hs 746.T GDSC2 2.9044 15.0887 -4.5271 23.6459
RF-48 GDSC2 2.9687 4.8771 0.354 0.8598
GCIY GDSC2 3.2076 5.0412 0.3924 0.5743
SNG-M GDSC2 3.7191 5.7519 0.3346 0.4787
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC2 1.0454 2.9014 0.0869 5.6508
CAL-62 GDSC2 1.1862 4.072 -0.3837 8.2283
ASH-3 GDSC2 1.5743 8.2443 -2.1553 17.4377
BHT-101 GDSC2 2.1592 9.3853 -2.2702 16.4674
8305C GDSC2 2.1835 5.1247 -0.1791 4.6411
HTC-C3 GDSC2 2.3041 8.1287 -1.5446 12.3161
IHH-4 GDSC2 2.4437 4.1332 0.4104 1.0982
TT2609-C02 GDSC2 2.7329 9.473 -1.8936 13.1822
B-CPAP GDSC2 2.7584 10.1655 -2.2128 14.7346
WRO GDSC2 2.8002 9.9052 -2.0561 13.8589
FTC-133 GDSC2 2.9634 5.0021 0.3026 1.0594
8505C GDSC2 3.3433 13.8659 -3.6 19.4344
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DOK GDSC2 0.6779 7.6494 -2.5968 22.2384
HSC-2 GDSC2 0.9512 3.6115 -0.3466 8.6656
SAS GDSC2 1.1186 3.8539 -0.3294 8.0747
HO-1-N-1 GDSC2 1.2042 4.0616 -0.3642 8.0564
UPCI-SCC-090 GDSC2 1.2444 15.5608 -6.0777 31.7139
Detroit 562 GDSC2 1.6038 7.1859 -1.6053 14.4263
FaDu GDSC2 1.6503 4.1024 -0.0483 4.9675
SAT [Human HNSCC] GDSC2 1.9438 6.1202 -0.8225 9.0061
JHU-022 GDSC2 2.0126 8.1116 -1.7512 14.1589
NCI-H3118 GDSC2 2.0413 4.7016 -0.0716 4.286
SKN-3 GDSC2 2.1395 9.9377 -2.5583 17.9005
SCC-4 GDSC2 2.323 9.4515 -2.1802 15.612
BICR 10 GDSC2 2.3258 12.5021 -3.6869 22.1452
CAL-27 GDSC2 2.3367 6.2983 -0.635 7.0155
SCC-9 GDSC2 2.4103 11.0663 -2.9116 18.8127
Ca9-22 GDSC2 2.5722 8.9086 -1.7329 12.7078
BICR 22 GDSC2 2.8378 4.257 0.5338 0.3661
HSC-3 GDSC2 2.9906 4.4159 0.5355 0.2957
HSC-4 GDSC2 2.994 4.3759 0.551 0.2596
BB49-HNC GDSC2 3.0852 14.9194 -4.3076 22.526
SCC-15 GDSC2 3.1468 5.1354 0.3314 0.8102
CAL-33 GDSC2 3.4191 5.5955 0.2713 0.8289
BICR 78 GDSC2 3.4769 16.0095 -4.5539 22.4631
LB771-HNC GDSC2 3.549 16.5656 -4.7741 22.9948
OSC-20 GDSC2 3.7466 5.5954 0.4008 0.3168
PCI-04B GDSC2 4.3994 6.546 0.3079 0.2977
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC2 0.1983 4.596 -1.5032 18.1393
BFTC-905 GDSC2 0.9028 5.1118 -1.1374 13.7073
639V GDSC2 1.3567 4.2151 -0.3208 7.3768
TCCSUP GDSC2 1.9017 5.5085 -0.5542 7.4857
HT-1197 GDSC2 1.9743 6.2375 -0.8579 9.1461
SW1710 GDSC2 2.1519 7.2079 -1.2042 10.7587
647V GDSC2 2.4949 7.1069 -0.9154 8.3184
RT-112 GDSC2 2.6763 4.4139 0.4057 0.9
J82 GDSC2 2.7613 7.4355 -0.8949 7.6528
CAL-29 GDSC2 2.7912 4.593 0.3867 0.8776
RT-4 GDSC2 3.636 13.9827 -3.4473 18.2099
5637 GDSC2 3.9846 6.4617 0.1793 0.7741
SW780 GDSC2 4.9085 18.2396 -4.6199 19.8048
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC2 -0.3941 1.818 -0.8029 16.2459
NEC8 GDSC2 0.4987 2.3717 -0.1381 8.8094
BPH-1 GDSC2 0.6445 8.0376 -2.8193 23.3476
DoTc2 4510 GDSC2 1.0894 6.5932 -1.7224 16.5288
SKN GDSC2 1.1863 7.965 -2.3285 19.4071
TC-YIK GDSC2 1.1914 7.8936 -2.2887 19.1955
OVCA420 GDSC2 1.5129 4.3988 -0.2932 6.8075
MS751 GDSC2 1.5894 7.2713 -1.659 14.7636
DSH1 GDSC2 1.6188 12.3216 -4.1537 25.6046
Ca Ski GDSC2 1.816 5.2063 -0.4679 7.1589
HEY GDSC2 2.207 7.7174 -1.4136 11.8189
LB831-BLC GDSC2 2.2191 8.7973 -1.9352 14.6179
SiSo GDSC2 2.2485 13.4204 -4.2028 24.1517
CAL-39 GDSC2 2.2723 8.4907 -1.7452 13.4828
SKG-IIIa GDSC2 2.2766 16.9285 -5.927 28.9092
PWR-1E GDSC2 2.2962 9.0143 -1.9849 14.6858
SW756 GDSC2 2.5801 6.2882 -0.4719 5.5841
C-33 A GDSC2 2.7208 6.1622 -0.3271 4.5126
HEC-1 GDSC2 2.8144 12.3425 -3.2394 19.2193
ME-180 GDSC2 3.1532 12.8583 -3.2445 18.4597
C-4-I GDSC2 3.4042 5.3125 0.3712 0.5306
HT-3 GDSC2 3.5626 5.686 0.2967 0.6609
OVMIU GDSC2 3.736 16.1125 -4.4151 21.465
PEO1 GDSC2 3.8855 6.8051 0.0053 1.4388
SiHa GDSC2 4.3359 17.9455 -4.8792 21.7074
HeLa GDSC2 6.4697 20.8017 -4.7978 17.6486
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8234).