Details of the Drug

General Information of Drug (ID: DMLZTP9)

Drug Name
Ipecac
Synonyms Ipecac syrup
Indication
Disease Entry ICD 11 Status REF
Poison intoxication NE6Z Approved [1]
Affected Organisms
Humans
ATC Code
R05CA04: Ipecac
R05CA: Expectorants
R05C: EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
R05: COUGH AND COLD PREPARATIONS
R: RESPIRATORY SYSTEM
V03AB01: Ipecac
V03AB: Antidotes
V03A: ALL OTHER THERAPEUTIC PRODUCTS
V03: ALL OTHER THERAPEUTIC PRODUCTS
V: VARIOUS
ADMET Property
Absorption Tmax
The time to maximum plasma concentration (Tmax) is 2-12 h []
Bioavailability
The bioavailability of drug is 30-60% []
Elimination
Due to the emetic function, even 76% of the administered dose is vomited []
Half-life
The concentration or amount of drug in body reduced by one-half in 0.5 - 1 hour [2]
Metabolism
The drug is metabolized via the CYP2D6 []
Cross-matching ID
UNII
62I3C8233L
DrugBank ID
DB13293
TTD ID
D03FEO
INTEDE ID
DR0877

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2D6 (CYP2D6)
Main DME 		DECB0K3 CP2D6_HUMAN Substrate [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
3 Medical Toxicology of Drug Abuse: Synthesized Chemicals and Psychoactive Plants. doi: 10.1002/9781118105955.ch13