Details of the Drug

General Information of Drug (ID: DMM25B1)

Drug Name

BMN 250

Synonyms

tralesinidase alfa

Indication

Disease Entry	ICD 11	Status	REF
Mucopolysaccharidosis type IIIB	5C56.3Y	Phase 1/2	[1]
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Drug Type

Fusion protein

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Alpha-N-acetylglucosaminidase (NAGLU)	TTDM6HZ	ANAG_HUMAN	Replacement	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B. Drug Deliv Transl Res. 2020 Apr;10(2):425-439.
2	Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B. Drug Deliv Transl Res. 2020 Apr;10(2):425-439.