Details of the Drug

General Information of Drug (ID: DMM4JCA)

• Drug Name: HG-1051
• Synonyms: CD136 modulator (inflammation/immune disorders), Human Genome Sciences; CD137 antigen modulator (inflammation/immune disorders), Human Genome Sciences; CDw137 modulator (inflammation/immune disorders), Human Genome Sciences; Homolog of mouse Ly63 modulator (inflammation/immune disorders), Human Genome Sciences; ILA modulator (inflammation/immune disorders), Human Genome Sciences; MGC2172 modulator (inflammation/immune disorders), Human Genome Sciences; T cell antigen ILA modulator (inflammation/immune disorders), Human Genome Sciences; TNFRSF9 modulator (inflammation/immune disorders), Human Genome Sciences; Tumor necrosis factor receptor superfamily member 9 modulator (inflammation/immune disorders), Human Genome Sciences; Homolog of mouse 4-1BB modulator (inflammation/immune disorders), Human Genome Sciences; Human 4-1BB receptor splicing varifant modulator (inflammation/immune disorders), Human Genome Sciences; Induced by lymphocyte activation (ILA) modulator (inflammation/immune disorders), Human Genome Sciences; Interleukin-activated receptor modulator (inflammation/immune disorders), Human Genome Sciences; 4-1BB ligand receptor modulator (inflammation/immune disorders), Human Genome Sciences; 4-1BB modulator (inflammation/immune disorders), Human Genome Sciences

Indication

Disease Entry	ICD 11	Status	REF
Immune System disease	4A01-4B41	Investigative	[1]

• Cross-matching ID: TTD ID: D07RXX

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Co-stimulatory molecule 4-1BB (CD137)	TTPW9LJ	TNR9_HUMAN	Modulator	[1]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1878).