Details of the Drug

General Information of Drug (ID: DMMAUEB)

• Drug Name: Genz-667348
• Synonyms: DHODH inhibitors (malaria); DHODH inhibitors (malaria), Genzyme/Medicines for Malaria Venture; Dihydroorotate dehydrogenase inhibitors (malaria), Genzyme/Medicines for Malaria Venture

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Investigative	[1]

• Chemical Identifiers:
  Formula: C17H14F3N3O2S
  Canonical SMILES: CC1=NC2=C(N1C3=CC=C(S3)C(=O)NC4CC4)C=CC(=C2)OC(F)(F)F
  InChI: InChI=1S/C17H14F3N3O2S/c1-9-21-12-8-11(25-17(18,19)20)4-5-13(12)23(9)15-7-6-14(26-15)16(24)22-10-2-3-10/h4-8,10H,2-3H2,1H3,(H,22,24)
  InChIKey: ACFOZQUWTKSSQQ-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 46846313
  ChEBI ID: CHEMBL1234899
  TTD ID: D0W8CA
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

References

• [1] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.