Details of the Drug

General Information of Drug (ID: DMMAUEB)

Drug Name

Genz-667348

Synonyms

DHODH inhibitors (malaria); DHODH inhibitors (malaria), Genzyme/Medicines for Malaria Venture; Dihydroorotate dehydrogenase inhibitors (malaria), Genzyme/Medicines for Malaria Venture

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Investigative	[1]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C17H14F3N3O2S
Canonical SMILES: CC1=NC2=C(N1C3=CC=C(S3)C(=O)NC4CC4)C=CC(=C2)OC(F)(F)F
InChI: 1S/C17H14F3N3O2S/c1-9-21-12-8-11(25-17(18,19)20)4-5-13(12)23(9)15-7-6-14(26-15)16(24)22-10-2-3-10/h4-8,10H,2-3H2,1H3,(H,22,24)
InChIKey: ACFOZQUWTKSSQQ-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 46846313
TTD ID: D0W8CA

References

1	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.