Details of the Drug

General Information of Drug (ID: DMME09C)

Drug Name

1H-Imidazo[4,5-c]quinolin-4-ylamine HCl

Synonyms

3H-imidazo[4,5-c]quinolin-4-amine; 1H-Imidazo[4,5-c]quinolin-4-amine; CHEMBL19191; 4-amino-1h-imidazo[4,5-c]quinoline; 132207-04-6; SCHEMBL482926; SCHEMBL212131; imidazo[4,5-c]quinolin-4-amine; imidazo(4,5-c)quinolin 4-amine; WUUCVVFSWNXYRD-UHFFFAOYSA-N; HQBUPOAKJGJGCD-UHFFFAOYSA-N; CS-B1117; BDBM50011593; ZINC28222586; AKOS027322300; 1h-imidazo-[4,5-c]quinolin-4-amine; SB22857; 1H-Imidazo[4,5-c]quinolin-4-ylamine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

184.2

Logarithm of the Partition Coefficient (xlogp)

1.4

Rotatable Bond Count (rotbonds)

0

Hydrogen Bond Donor Count (hbonddonor)

2

Hydrogen Bond Acceptor Count (hbondacc)

3

Chemical Identifiers

Formula: C10H8N4
IUPAC Name: 3H-imidazo[4,5-c]quinolin-4-amine
Canonical SMILES: C1=CC=C2C(=C1)C3=C(C(=N2)N)NC=N3
InChI: InChI=1S/C10H8N4/c11-10-9-8(12-5-13-9)6-3-1-2-4-7(6)14-10/h1-5H,(H2,11,14)(H,12,13)
InChIKey: HQBUPOAKJGJGCD-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 14896613
TTD ID: D08MRB

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Adenosine A1 receptor (ADORA1)	TTK25J1	AA1R_HUMAN	Inhibitor	[1]
Adenosine A2a receptor (ADORA2A)	TTM2AOE	AA2AR_HUMAN	Inhibitor	[1]
Adenosine A2b receptor (ADORA2B)	TTNE7KG	AA2BR_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	1H-imidazo[4,5-c]quinolin-4-amines: novel non-xanthine adenosine antagonists. J Med Chem. 1991 Mar;34(3):1202-6.