Details of the Drug

General Information of Drug (ID: DMMM2YQ)

Drug Name

K-Ras(G12C) inhibitor 6

Synonyms

GTPL8021; AKOS029769936

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C17H22Cl2N2O3S
Canonical SMILES: C1CN(CCC1NC(=O)CCCS)C(=O)COC2=C(C=C(C=C2)Cl)Cl
InChI: 1S/C17H22Cl2N2O3S/c18-12-3-4-15(14(19)10-12)24-11-17(23)21-7-5-13(6-8-21)20-16(22)2-1-9-25/h3-4,10,13,25H,1-2,5-9,11H2,(H,20,22)
InChIKey: ZPXCEHMKUTXHRZ-UHFFFAOYSA-N

Cross-matching ID

References

1	K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature. 2013 Nov 28;503(7477):548-51.