Details of the Drug

General Information of Drug (ID: DMMQHPB)

• Drug Name: VTS-270
• Synonyms: ODLHGICHYURWBS-UHFFFAOYSA-N; AC1N9NUY; SCHEMBL19239855; 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-(2-hydroxypropyl)-beta-cyclodextrin

Indication

Disease Entry	ICD 11	Status	REF
Niemann-pick disease	5C56.0Y	Phase 3	[1]

• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C63H112O42
  Canonical SMILES: CC(COCC1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)COCC(C)O)O)O)O
  InChI: InChI=1S/C63H112O42/c1-22(64)8-85-15-29-50-36(71)43(78)57(92-29)100-51-30(16-86-9-23(2)65)94-59(45(80)38(51)73)102-53-32(18-88-11-25(4)67)96-61(47(82)40(53)75)104-55-34(20-90-13-27(6)69)98-63(49(84)42(55)77)105-56-35(21-91-14-28(7)70)97-62(48(83)41(56)76)103-54-33(19-89-12-26(5)68)95-60(46(81)39(54)74)101-52-31(17-87-10-24(3)66)93-58(99-50)44(79)37(52)72/h22-84H,8-21H2,1-7H3
  InChIKey: ODLHGICHYURWBS-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 4363642
  CAS Number: 128446-35-5
  UNII: 8W6Q67R6NX
  DrugBank ID: DB15146
  TTD ID: D01SNZ

References

• [1] ClinicalTrials.gov (NCT03643562) Niemann-Pick Type C Treatment With Adrabetadex for Symptoms of Brain and Nervous System. U.S. National Institutes of Health.