Details of the Drug

General Information of Drug (ID: DMMWEH6)

Drug Name

AVP-21D9

Synonyms

Thravixa; AVP-1C6; AVP-22G12; AVP-8C1; Anthrax antibody, AVANIR; Anthrax toxin Mab, Xenerex; Protective antigen-targeting human monoclonal antibodies (intravenous, anthrax), AVANIR; Protective antigen-targeting human monoclonal antibodies (intravenous, anthrax), Emergent

Indication

Disease Entry	ICD 11	Status	REF
Bacillus anthracis infection	1G40	Phase 1	[1]

Drug Type

Antibody

Cross-matching ID

UNII: 6RUU8A4K0R
DrugBank ID: DB17798
TTD ID: D0L8OP

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Protective antigen (Bact pagA)	TT3YGCD	PAG_BACAN	Not Available	[2]

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT01202695) Safety and Pharmacokinetics Study of Human Monoclonal Antibody (AVP-21D9). U.S. National Institutes of Health.
2	Efficacy and Safety of AVP-21D9, an Anthrax Monoclonal Antibody, in Animal Models and Humans. Antimicrob Agents Chemother. 2014 July; 58(7): 3618-3625.