General Information of Drug (ID: DMMWEH6)

Drug Name
AVP-21D9
Synonyms
Thravixa; AVP-1C6; AVP-22G12; AVP-8C1; Anthrax antibody, AVANIR; Anthrax toxin Mab, Xenerex; Protective antigen-targeting human monoclonal antibodies (intravenous, anthrax), AVANIR; Protective antigen-targeting human monoclonal antibodies (intravenous, anthrax), Emergent
Indication
Disease Entry ICD 11 Status REF
Bacillus anthracis infection 1G40 Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
UNII
6RUU8A4K0R
DrugBank ID
DB17798
TTD ID
D0L8OP

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Protective antigen (Bact pagA) TT3YGCD PAG_BACAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01202695) Safety and Pharmacokinetics Study of Human Monoclonal Antibody (AVP-21D9). U.S. National Institutes of Health.
2 Efficacy and Safety of AVP-21D9, an Anthrax Monoclonal Antibody, in Animal Models and Humans. Antimicrob Agents Chemother. 2014 July; 58(7): 3618-3625.