Details of the Drug

General Information of Drug (ID: DMN2XK6)

Drug Name
Q203
Synonyms
Telacebec; 1334719-95-7; UNII-55G92WGH3X; 55G92WGH3X; Q-203; CHEMBL3298910; SCHEMBL12295312; MMV687696; BDBM50022086; ZINC169325657; CS-6412; Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-N-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl)phenyl)methyl)-; AS-35270; HY-101040; Q 203; EN300-218150; Z2235679010; 6-chloro-2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine-3-carboxamide; 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]-1-piperidyl]phenyl]methyl]im
Indication
Disease Entry ICD 11 Status REF
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [1]
Tuberculosis 1B10-1B1Z Phase 1 [2]
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C29H28ClF3N4O2
Canonical SMILES
CCC1=C(N2C=C(C=CC2=N1)Cl)C(=O)NCC3=CC=C(C=C3)N4CCC(CC4)C5=CC=C(C=C5)OC(F)(F)F
InChI
InChI=1S/C29H28ClF3N4O2/c1-2-25-27(37-18-22(30)7-12-26(37)35-25)28(38)34-17-19-3-8-23(9-4-19)36-15-13-21(14-16-36)20-5-10-24(11-6-20)39-29(31,32)33/h3-12,18,21H,2,13-17H2,1H3,(H,34,38)
InChIKey
OJICYBSWSZGRFB-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
68234908
ChEBI ID
CHEMBL3298910
CAS Number
1334719-95-7
UNII
55G92WGH3X
DrugBank ID
DB17754
TTD ID
D03SQT
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

References

1 ClinicalTrials.gov (NCT04847583) A Phase 2 Study to Evaluate Biomarker Change, Efficacy, Pharmacokinetics, Safety and Tolerability of Telacebec (Q203) in Covid-19 Patients. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)