Details of the Drug

General Information of Drug (ID: DMN4H8N)

Drug Name
KAF156
Indication
Disease Entry ICD 11 Status REF
Malaria 1F40-1F45 Phase 2 [1]
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C22H23F2N5O
Canonical SMILES
CC1(C2=NC(=C(N2CCN1C(=O)CN)NC3=CC=C(C=C3)F)C4=CC=C(C=C4)F)C
InChI
InChI=1S/C22H23F2N5O/c1-22(2)21-27-19(14-3-5-15(23)6-4-14)20(26-17-9-7-16(24)8-10-17)28(21)11-12-29(22)18(30)13-25/h3-10,26H,11-13,25H2,1-2H3
InChIKey
BUPRVECGWBHCQV-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
49856296
ChEBI ID
CHEMBL2058833
CAS Number
1261113-96-5
UNII
85VMN9JU7A
DrugBank ID
DB16173
TTD ID
D03QHC
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Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

References

1 ClinicalTrials.gov (NCT01753323) Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection. U.S. National Institutes of Health.