Details of the Drug

General Information of Drug (ID: DMN6J18)

Drug Name
Vupanorsen
Synonyms IONIS-ANGPTL3-LRx; AKCEA-ANGPTL3-LRx
Indication
Disease Entry ICD 11 Status REF
Hypertriglyceridemia 5C80.1 Phase 2 [1]
Non-alcoholic fatty liver disease DB92 Phase 2 [1]
Type 2 diabetes 5A11 Phase 2 [1]
Drug Type
Antisense oligonucleotide
Sequence
GGACATTGCCAGTAATCGCA
Cross-matching ID
TTD ID
DDU2Y0
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ANGPTL3 messenger RNA (ANGPTL3 mRNA) TT59GO7 ANGL3_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03371355) Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.