Details of the Drug

General Information of Drug (ID: DMN8HRU)

Drug Name
Methoxyphenamine
Synonyms
Euspirol; METHOXYPHENAMINE; Methamphetamine, 2-methoxy; Methoxifenaminio; Methoxiphenadrin; Methoxiphenadrinum; Methoxyphenadrine; Methoxyphenamin; Methoxyphenamine [INN:BAN]; Methoxyphenaminum; Methoxyphenaminum [INN-Latin]; Metossifenamina [DCIT]; Metoxifenaminio [INN-Spanish]; Orthoxine; Ortodrinex; Ortoxine; Oxalacetic acid orthoxine; Proasma; 2-Methoxy-N,alpha-dimethylphenethylamin; 2-Methoxy-N-methylamphetamine; 2-Methoxymethamphetamine; 93-30-1; Asmi; EINECS 202-237-7; o-Methoxy-N,alpha-dimethylphenethylamine
ATC Code
R03CB02: Methoxyphenamine
R03CB: Non-selective beta-adrenoreceptor agonists
R03C: ADRENERGICS FOR SYSTEMIC USE
R03: DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R: RESPIRATORY SYSTEM
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 179.26
Logarithm of the Partition Coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C11H17NO
IUPAC Name
1-(2-methoxyphenyl)-N-methylpropan-2-amine
Canonical SMILES
CC(CC1=CC=CC=C1OC)NC
InChI
InChI=1S/C11H17NO/c1-9(12-2)8-10-6-4-5-7-11(10)13-3/h4-7,9,12H,8H2,1-3H3
InChIKey
OEHAYUOVELTAPG-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
4117
ChEBI ID
CHEMBL134817
CAS Number
93-30-1
UNII
J3Z5SRI26Z
DrugBank ID
DB13624
INTEDE ID
DR1049
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2D6 (CYP2D6)
Main DME 		DECB0K3 CP2D6_HUMAN Substrate [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Metabolism of methoxyphenamine and 2-methoxyamphetamine in P4502D6-transfected cells and cell preparations. Xenobiotica. 1995 Sep;25(9):895-906.