Details of the Drug

General Information of Drug (ID: DMNEY58)

Drug Name
ML272
Synonyms
N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide; CHEMBL492797; 1130067-18-3; ML272; VU0155056-2; SCHEMBL2724877; BDBM87245; cid_53481919; CHEBI:131157; NCGC00386898-01; VU0155056-3; VU0155056-1; US9453017, 3; VU0156056 (1); N-[2-[4-(2-keto-3H-benzimidazol-1-yl)piperidino]ethyl]-2-naphthamide;hydrochloride; N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-2-naphthalenecarboxamide;hydrochloride; N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 414.5
Logarithm of the Partition Coefficient (xlogp) 4.2
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C25H26N4O2
IUPAC Name
N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide
Canonical SMILES
C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCNC(=O)C4=CC5=CC=CC=C5C=C4
InChI
InChI=1S/C25H26N4O2/c30-24(20-10-9-18-5-1-2-6-19(18)17-20)26-13-16-28-14-11-21(12-15-28)29-23-8-4-3-7-22(23)27-25(29)31/h1-10,17,21H,11-16H2,(H,26,30)(H,27,31)
InChIKey
IXLLRNNFUYEADZ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
25105704
ChEBI ID
CHEBI:131157
TTD ID
D0CI4A

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phospholipase D1 (PLD1) TT3T17P PLD1_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Phospholipase D1 (PLD1) DTT PLD1 7.36E-01 0.08 0.15
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 147 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 6.8091 11.4339 3.9573 7.3951
JK1 CTRP2 7.9936 12.5667 4.2292 4.5821
JM1 CTRP2 5.3694 10.3119 3.325 12.7783
EoL-1 CTRP2 3.2094 5.4159 3.0967 19.273
Daudi CTRP2 3.7726 6.2651 3.5015 16.0919
Pfeiffer CTRP2 4.3009 7.1921 3.74 13.6811
GA-10 CTRP2 4.338 6.4785 4.0479 12.4063
KMS-20 CTRP2 4.405 7.174 3.8571 12.9433
KMS-12-BM CTRP2 4.4232 5.3054 4.4092 10.8476
MJ CTRP2 4.4327 10.0428 2.5826 17.9037
LP-1 CTRP2 4.5169 9.3 3.0173 15.9861
TALL-1 [Human adult T-ALL] CTRP2 4.5191 6.0186 4.3868 10.6237
697 CTRP2 4.5443 6.984 4.0809 11.6975
KMS-34 CTRP2 4.5682 5.5607 4.535 9.9471
DEL CTRP2 4.6004 5.2746 4.5949 9.6387
KMS-11 CTRP2 4.663 6.5286 4.3815 10.2179
OPM-2 CTRP2 4.7077 7.405 4.0758 11.2781
KMS-26 CTRP2 4.9283 7.1808 4.4006 9.4171
KMS-21-BM CTRP2 4.9312 7.8522 4.1022 10.6012
KMS-18 CTRP2 4.9428 5.9476 4.8671 7.6015
SUP-T11 CTRP2 5.0001 5.9833 4.9208 7.2331
AML-193 CTRP2 5.0545 6.3789 4.8573 7.305
HH [Human lymphoma] CTRP2 5.0711 6.9327 4.655 8.0386
HPB-ALL CTRP2 5.1318 6.1318 5.0233 6.4625
NU-DUL-1 CTRP2 5.1492 7.05 4.6848 7.716
RS4;11 CTRP2 5.1638 6.4097 4.9637 6.5916
KHM-1B CTRP2 5.268 8.6686 4.04 10.0528
U-937 CTRP2 5.3287 6.6502 5.0429 5.8321
Mono-Mac-1 CTRP2 5.3629 7.0602 4.897 6.3229
SET-2 CTRP2 5.3728 6.0322 5.3147 4.677
HD-MY-Z CTRP2 5.3781 9.504 3.7321 11.0809
CA46 CTRP2 5.395 6.5026 5.1736 5.1443
Namalwa CTRP2 5.4228 6.5566 5.1804 5.0425
BDCM CTRP2 5.4399 6.2238 5.3283 4.4281
OCI-AML-3 CTRP2 5.445 6.229 5.3319 4.3997
THP-1 CTRP2 5.4703 6.5589 5.229 4.7255
EB1 CTRP2 5.507 6.564 5.2648 4.4873
KYO-1 CTRP2 5.5764 6.8946 5.1861 4.6259
M-07e CTRP2 5.7619 8.9026 4.3735 7.588
F-36P CTRP2 5.8269 9.4281 4.1681 8.3157
DND-41 CTRP2 5.8771 9.6154 4.1177 8.4255
SK-MM-2 CTRP2 6.005 7.5366 5.2652 3.3518
MOLP-2 CTRP2 6.1173 7.4601 5.3963 2.5867
K-562 CTRP2 6.4801 10.6825 4.0778 7.4589
MOLM-6 CTRP2 6.502 9.6882 4.5884 5.2915
EM-2 CTRP2 6.5986 9.9636 4.5253 5.3917
MOLT-3 CTRP2 6.7631 8.1163 5.5284 1.1122
BL-70 CTRP2 6.8082 8.1867 5.5229 1.0837
DB CTRP2 6.9137 10.7741 4.3591 5.5709
P12-Ichikawa CTRP2 6.9196 11.1046 4.2015 6.209
KE-37 CTRP2 6.9249 9.7984 4.8409 3.5906
JURL-MK1 CTRP2 6.9315 10.9977 4.2625 5.9395
MOTN-1 CTRP2 7.0115 11.1738 4.2342 5.9303
SUP-M2 CTRP2 7.069 9.9715 4.8551 3.3327
Toledo CTRP2 7.1108 18.5349 0.6641 19.101
MOLT-16 CTRP2 7.1335 9.4803 5.1269 2.1917
Ci-1 CTRP2 7.1392 8.2413 5.6692 0.3569
HuNS1 CTRP2 7.1618 9.2582 5.2456 1.7163
A3/Kawakami CTRP2 7.1949 9.043 5.3606 1.2711
Karpas-620 CTRP2 7.2379 12.3001 3.8468 7.1591
NB4 CTRP2 7.2702 8.6542 5.5644 0.5602
SU-DHL-10 CTRP2 7.3179 8.1861 5.7627 0.1028
L-428 CTRP2 7.3382 11.458 4.3251 5.0761
L-363 CTRP2 7.3521 8.9379 5.4875 0.7274
OCI-M1 CTRP2 7.3734 8.8381 5.5384 0.5671
Kasumi-1 CTRP2 7.4202 10.3386 4.9067 2.6879
ST486 CTRP2 7.4662 11.4674 4.4066 4.5734
MC116 CTRP2 7.4821 8.4682 5.7243 0.1191
HL-60 CTRP2 7.4898 10.6106 4.8239 2.9196
KMM-1 CTRP2 7.5294 9.9202 5.1594 1.6491
Peer CTRP2 7.5421 9.0422 5.5341 0.4808
OCI-AML-2 CTRP2 7.5492 8.851 5.6108 0.2996
SIG-M5 CTRP2 7.5786 8.5498 5.7312 0.0901
OCI-AML-5 CTRP2 7.5822 8.5691 5.7258 0.0959
TF-1 CTRP2 7.5825 9.5362 5.3526 0.9669
Hs 611.T CTRP2 7.5908 9.9061 5.1991 1.4561
KO52 CTRP2 7.5923 9.1218 5.5252 0.4765
RL CTRP2 7.5993 10.7488 4.8271 2.7802
P31/FUJ CTRP2 7.6042 8.6989 5.6883 0.1419
Karpas-299 CTRP2 7.6113 9.0828 5.5487 0.4105
SUP-B15 CTRP2 7.6205 11.306 4.5824 3.6853
NOMO-1 CTRP2 7.6733 8.8571 5.658 0.1705
SKM-1 CTRP2 7.6776 9.0087 5.6044 0.2636
PL21 CTRP2 7.6904 9.638 5.3634 0.8568
SU-DHL-4 CTRP2 7.7065 8.9355 5.6426 0.1861
CMK CTRP2 7.7313 9.8918 5.2782 1.0835
KMS-27 CTRP2 7.7367 10.5022 5.0178 1.9422
JJN-3 CTRP2 7.77 11.3121 4.6719 3.1657
JeKo-1 CTRP2 7.7919 10.8927 4.8752 2.3933
HT CTRP2 7.7945 9.1711 5.5912 0.248
OCI-Ly3 CTRP2 7.8009 11.5884 4.5635 3.5386
L-540 CTRP2 7.8031 10.0709 5.2391 1.1495
Kasumi-2 CTRP2 7.8186 11.3377 4.6894 3.0451
SU-DHL-1 CTRP2 7.893 9.2325 5.6073 0.1912
WSU-DLCL2 CTRP2 7.903 8.899 5.7265 0.0496
RPMI-8402 CTRP2 7.9246 9.9126 5.3623 0.7109
A4/Fukuda CTRP2 7.9425 11.3083 4.7754 2.5956
CML-T1 CTRP2 7.9572 9.4179 5.5651 0.2425
KM-H2 CTRP2 7.9581 9.9528 5.3616 0.6935
MOLP-8 CTRP2 7.9752 9.8588 5.4063 0.571
MOLM-13 CTRP2 7.9914 10.1588 5.2944 0.855
RCH-ACV CTRP2 8.034 9.8345 5.441 0.4615
Raji CTRP2 8.0545 9.4975 5.574 0.2003
KE-97 CTRP2 8.06 9.6389 5.5249 0.2812
ME1 CTRP2 8.0624 9.4683 5.5873 0.1782
NU-DHL-1 CTRP2 8.0635 9.8899 5.4324 0.4676
Ri-1 CTRP2 8.0723 11.6495 4.6971 2.7428
HEL CTRP2 8.0924 9.3074 5.6543 0.0897
RPMI-8226 CTRP2 8.0932 10.1037 5.3627 0.6173
JVM-3 CTRP2 8.1011 10.5273 5.1964 1.0619
MM1.S CTRP2 8.1065 10.1681 5.3433 0.6583
Ki-JK CTRP2 8.1345 16.1594 2.6051 10.6621
SR CTRP2 8.1427 9.8734 5.4714 0.3535
Karpas-422 CTRP2 8.1484 10.8657 5.0792 1.3806
PF-382 CTRP2 8.1664 11.0282 5.0198 1.5536
BV-173 CTRP2 8.1815 9.9468 5.4599 0.3619
HEL 92.1.7 CTRP2 8.1918 13.5898 3.876 5.6925
AMO1 CTRP2 8.1975 9.2398 5.7131 0.0336
U266B1 CTRP2 8.232 10.6799 5.1966 0.9749
KCL-22 CTRP2 8.2611 9.9738 5.4817 0.2938
Ku812 CTRP2 8.2622 9.955 5.489 0.2807
Granta-519 CTRP2 8.2667 10.33 5.3504 0.561
SUP-T1 CTRP2 8.2763 10.3906 5.3312 0.6013
RPMI-6666 CTRP2 8.2834 10.0664 5.4566 0.332
Jurkat CTRP2 8.2853 9.6575 5.6029 0.1135
SU-DHL-8 CTRP2 8.2881 9.6062 5.6215 0.0938
MOLT-13 CTRP2 8.2947 9.6946 5.5935 0.1223
EHEB CTRP2 8.3467 10.3573 5.3739 0.4735
OCI-Ly10 CTRP2 8.4181 10.9629 5.1693 0.9348
Reh CTRP2 8.4431 10.0152 5.5361 0.1639
MV4-11 CTRP2 8.4636 9.96 5.5626 0.1282
REC-1 CTRP2 8.4636 13.6164 4.0343 4.7538
SU-DHL-6 CTRP2 8.473 10.0163 5.5466 0.1451
MOLM-16 CTRP2 8.4972 9.8873 5.5993 0.0864
NALM-6 CTRP2 8.5149 10.335 5.4495 0.2728
MHH-CALL-4 CTRP2 8.5347 10.1544 5.521 0.1647
NCI-H929 CTRP2 8.5881 10.1786 5.5319 0.1415
LAMA-84 CTRP2 8.6051 10.3159 5.4903 0.19
HDLM-2 CTRP2 8.6446 11.1631 5.1921 0.7519
OCI-Ly19 CTRP2 8.6481 10.1334 5.5687 0.0946
EJM CTRP2 8.6835 11.6148 5.0304 1.1515
P3HR-1 CTRP2 8.6992 10.4893 5.4642 0.2048
L-1236 CTRP2 8.7004 10.5882 5.4295 0.2544
GDM-1 CTRP2 8.7251 11.1022 5.25 0.5808
SUP-HD1 CTRP2 8.7545 11.337 5.1726 0.744
MHH-CALL-3 CTRP2 9.2015 11.1873 5.4043 0.1803
Mino CTRP2 9.3985 23.0518 0.148 16.9107
⏷ Show the Full List of 147 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 5.2942 7.1428 4.7904 6.9234
TE15 CTRP2 7.3223 9.5494 5.2075 1.685
TE-4 CTRP2 4.7737 7.1182 4.267 10.352
OE21 CTRP2 5.2554 10.9221 2.9204 14.6689
TE-5 CTRP2 5.3711 10.3503 3.3075 12.8463
TE-6 CTRP2 5.7527 6.6407 5.4783 3.0096
TE-14 CTRP2 5.8164 9.9316 3.9077 9.4264
EC-GI-10 CTRP2 5.8757 9.9782 3.9352 9.1925
KYSE-410 CTRP2 6.1204 8.5379 4.8604 4.8319
TE-10 CTRP2 7.7399 15.2884 2.748 10.7302
TE-9 CTRP2 7.8707 9.6717 5.4332 0.5588
TE-1 CTRP2 7.936 9.9915 5.336 0.775
KYSE-150 CTRP2 7.9435 9.5245 5.5204 0.3306
OE19 CTRP2 8.0168 9.4356 5.5817 0.1982
KYSE-510 CTRP2 8.0869 12.5548 4.293 4.2244
OE33 CTRP2 8.2199 13.3536 4.0046 5.162
KYSE-180 CTRP2 8.3181 11.5273 4.8856 1.8613
COLO 680N CTRP2 8.4858 9.805 5.6231 0.068
KYSE-520 CTRP2 8.4954 13.9842 3.8837 5.283
KYSE-450 CTRP2 8.5512 15.2461 3.3274 7.3268
KYSE-140 CTRP2 8.5629 11.9631 4.8268 1.8487
KYSE-70 CTRP2 8.6603 10.4573 5.461 0.218
TE-11 CTRP2 9.4741 17.3249 2.9418 7.5814
KYSE-30 CTRP2 10.8326 18.496 3.2108 5.1684
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 10.6837 18.3241 3.2039 5.3348
MIA PaCa-2 CTRP2 5.3233 6.1023 5.2409 5.0944
Panc 10.05 CTRP2 5.4097 10.2484 3.3925 12.4142
SNU-410 CTRP2 5.8849 7.3405 5.259 3.6225
PaTu 8902 CTRP2 5.886 6.6189 5.6164 2.1302
SU.86.86 CTRP2 5.9473 7.0887 5.4393 2.7374
PSN1 CTRP2 5.9989 6.9843 5.536 2.2262
Capan-2 CTRP2 6.0169 11.3611 3.3631 11.2895
PaTu 8988s CTRP2 6.6694 15.7947 1.6798 16.541
KP-4 CTRP2 7.054 8.6542 5.4538 1.0827
Panc 04.03 CTRP2 7.1904 9.7654 5.0301 2.4928
QGP-1 CTRP2 7.5741 9.3098 5.4418 0.709
Capan-1 CTRP2 7.6071 10.4778 4.9548 2.2996
Panc 08.13 CTRP2 7.7987 11.4196 4.64 3.2525
Hs 766T CTRP2 7.8453 10.6357 5.0189 1.8349
YAPC CTRP2 7.8655 9.2032 5.6073 0.1988
SW1990 CTRP2 7.9282 10.039 5.3132 0.8426
SUIT-2 CTRP2 7.9312 9.1646 5.6456 0.1275
DAN-G CTRP2 7.9652 9.68 5.4708 0.4257
HuP-T4 CTRP2 7.985 14.5825 3.2645 8.3575
L3.3 CTRP2 8.0048 9.9806 5.3716 0.6416
PaTu 8988t CTRP2 8.0101 9.2144 5.657 0.0997
TCC-Pan2 CTRP2 8.0945 9.3882 5.6273 0.1188
PK-59 CTRP2 8.166 10.6495 5.1776 1.0723
PK-45H CTRP2 8.2065 11.4994 4.8382 2.1177
Panc 03.27 CTRP2 8.2373 13.4682 3.9621 5.3032
HPAC CTRP2 8.3455 9.6586 5.6239 0.0838
CFPAC-1 CTRP2 8.3497 10.0179 5.5001 0.2372
KP-3 CTRP2 8.4269 10.8298 5.2261 0.7814
AsPC-1 CTRP2 8.4709 13.4198 4.129 4.391
HuP-T3 CTRP2 8.5096 10.6461 5.3326 0.494
BxPC-3 CTRP2 8.5518 17.3007 2.344 11.0051
KP-2 CTRP2 8.5995 13.9509 3.9632 4.8604
Panc 02.03 CTRP2 8.9436 10.5957 5.5153 0.2252
HPAF-II CTRP2 9.2207 20.555 1.2354 13.8471
SNU-213 CTRP2 9.378 18.4777 2.3382 9.8697
Panc 05.04 CTRP2 9.8835 19.5086 2.1797 9.7647
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 10.2245 25.6574 -0.5346 17.6022
Malme-3M CTRP2 4.4208 7.0873 3.9089 12.7002
MeWo CTRP2 5.0851 7.3023 4.5072 8.5877
WM115 CTRP2 5.345 5.937 5.3076 4.7885
Hs 940.T CTRP2 5.3503 10.5297 3.2 13.3307
UACC-257 CTRP2 5.5134 5.944 5.489 3.6214
RVH-421 CTRP2 5.6084 6.0398 5.5698 3.0397
WM266-4 CTRP2 5.6175 6.0835 5.5673 3.0212
IGR-37 CTRP2 5.6711 6.3585 5.5227 3.0393
UACC-62 CTRP2 5.6758 6.0812 5.6315 2.6122
WT2-iPS CTRP2 5.6798 6.1442 5.6153 2.6601
HT-144 CTRP2 5.7022 6.2783 5.5886 2.6986
Hs 688(A).T CTRP2 6.535 7.9877 5.445 1.7152
SK-MEL-24 CTRP2 6.7309 10.6217 4.2997 6.1088
SK-MEL-28 CTRP2 7.2154 8.5527 5.5796 0.5527
RPMI-7951 CTRP2 7.227 8.751 5.5033 0.7718
WM983B CTRP2 7.2731 13.336 3.365 9.0503
SK-MEL-30 CTRP2 7.2892 9.6531 5.1416 1.9596
IPC-298 CTRP2 7.422 9.1383 5.4387 0.8233
Hs 934.T CTRP2 7.4442 8.7678 5.598 0.3749
SK-MEL-1 CTRP2 7.4994 9.1443 5.4737 0.6675
COLO 800 CTRP2 7.5151 12.411 3.9878 6.1754
SK-MEL-31 CTRP2 7.5665 9.3631 5.4164 0.787
Hs 839.T CTRP2 7.5738 8.5709 5.7221 0.1022
SK-MEL-5 CTRP2 7.5877 9.6407 5.3112 1.092
HMCB CTRP2 7.5916 8.7739 5.6565 0.1967
A101D CTRP2 7.6303 13.6139 3.486 8.0105
Hs 944.T CTRP2 7.663 11.2962 4.6136 3.5136
WM1799 CTRP2 7.6933 9.1881 5.5434 0.3847
A2058 CTRP2 7.7429 8.7096 5.7349 0.061
Mel JuSo CTRP2 7.8128 9.5174 5.468 0.5035
G-361 CTRP2 7.9065 9.5792 5.4844 0.4214
IGR-39 CTRP2 7.9228 9.037 5.6867 0.0822
Hs 936.T CTRP2 7.9343 9.0468 5.6874 0.0798
IGR-1 CTRP2 7.9441 9.6242 5.4832 0.4079
MDA-MB-435S CTRP2 7.9726 9.2261 5.6393 0.1273
Hs 294T CTRP2 7.9866 9.2514 5.6356 0.1292
A-375 CTRP2 8.0131 9.418 5.5866 0.1916
WM88 CTRP2 8.2112 10.1478 5.3965 0.4821
Hs 895.T CTRP2 8.2168 9.3092 5.6966 0.0417
SK-MEL-3 CTRP2 8.2296 13.8398 3.7827 6.0036
Hs 852.T CTRP2 8.2431 9.9353 5.4887 0.2871
Mel Ho CTRP2 8.2481 9.7077 5.572 0.1575
COLO 829 CTRP2 8.268 10.4953 5.2867 0.7141
WM793 CTRP2 8.4108 10.0177 5.5232 0.188
LOX-IMVI CTRP2 8.4399 10.3026 5.432 0.3252
K029AX CTRP2 8.4923 9.4221 5.7504 0.0087
SK-MEL-2 CTRP2 8.768 21.7537 0.3278 17.3435
COLO 792 CTRP2 8.8732 10.798 5.42 0.2266
CJM [Human melanoma] CTRP2 13.9418 26.9546 1.2062 8.4138
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 5.4284 10.6488 3.2107 13.119
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-BE(2) CTRP2 6.0431 7.3147 5.4081 2.677
KP-N-SI9s CTRP2 7.3418 9.3418 5.3101 1.3066
NH-6 CTRP2 7.4443 11.9249 4.1732 5.5344
Kelly CTRP2 7.9159 10.4905 5.1192 1.4393
SK-N-FI CTRP2 7.9185 15.6425 2.7034 10.6217
SK-N-SH CTRP2 7.9349 13.666 3.6707 6.8376
SK-N-AS CTRP2 8.0263 10.4237 5.2028 1.0952
CHP-212 CTRP2 8.0424 10.3063 5.2586 0.9225
CHP-126 CTRP2 8.0818 9.729 5.5004 0.3193
MHH-NB-11 CTRP2 8.2052 9.8411 5.5082 0.2651
NB1 CTRP2 8.2496 10.1118 5.4261 0.4038
KP-N-YN CTRP2 8.4839 10.0044 5.5546 0.1338
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 CTRP2 5.7729 6.6714 5.4834 2.9401
HuH-28 CTRP2 8.1351 9.5365 5.5904 0.1573
SNU-308 CTRP2 8.2181 9.9548 5.4717 0.3263
SNU-1079 CTRP2 8.2701 17.7811 1.9117 12.9849
SNU-1196 CTRP2 8.279 9.7961 5.5524 0.1773
SNU-478 CTRP2 8.3639 10.4103 5.361 0.494
SNU-869 CTRP2 9.8952 18.5413 2.6392 8.148
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-ES-1 CTRP2 5.217 6.5181 4.9791 6.3837
A-673 CTRP2 5.33 6.0851 5.2532 5.0294
SJSA-1 CTRP2 5.6526 8.264 4.5933 6.9002
SaOS-2 CTRP2 5.6878 6.6017 5.4323 3.3556
SK-N-MC CTRP2 6.9663 11.2891 4.145 6.3668
Hs 822.T CTRP2 7.5153 8.3982 5.7607 0.068
SW1353 CTRP2 7.5703 9.8806 5.1991 1.4744
TC71 CTRP2 7.8105 8.8643 5.706 0.0794
HOS CTRP2 8.2025 17.2865 2.1046 12.4009
MHH-ES-1 CTRP2 8.2165 11.572 4.812 2.1979
Hs 888.T CTRP2 8.2344 9.688 5.5739 0.158
CAL-78 CTRP2 8.2792 9.8083 5.5482 0.1831
G-292 clone A141B1 CTRP2 8.3222 10.2588 5.4008 0.4271
MG-63 CTRP2 12.3594 25.5406 0.9213 10.8381
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 70 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-453 CTRP2 4.4038 6.6569 4.0559 12.1865
HCC1569 CTRP2 4.8634 6.864 4.4663 9.3341
DU4475 CTRP2 4.8676 7.4683 4.212 10.3227
HCC1428 CTRP2 5.6694 6.3283 5.5336 3.0015
CAL-85-1 CTRP2 6.0372 11.0228 3.5492 10.4819
T-47D CTRP2 6.2995 13.0606 2.7465 13.2344
Hs 578T CTRP2 6.878 13.9523 2.7619 12.1142
AU565 CTRP2 7.395 16.9999 1.6475 15.3515
HCC1419 CTRP2 7.5043 10.7048 4.7893 3.034
KPL-1 CTRP2 7.5152 12.2897 4.0462 5.9414
MDA-MB-468 CTRP2 7.5469 12.5664 3.9347 6.3419
HDQ-P1 CTRP2 7.6756 9.9329 5.2323 1.2728
HCC38 CTRP2 7.7251 14.4847 3.1297 9.2732
MDA-MB-361 CTRP2 7.7449 11.5642 4.5401 3.6951
BT-20 CTRP2 7.7461 12.4312 4.1336 5.2743
HMC-1-8 CTRP2 7.7791 8.8897 5.6859 0.1071
CAL-148 CTRP2 7.795 9.142 5.6021 0.2284
HCC2218 CTRP2 7.8358 10.9319 4.8828 2.3206
JIMT-1 CTRP2 7.855 9.0731 5.6497 0.1383
UACC-812 CTRP2 7.8779 9.7232 5.4162 0.5975
SK-BR-3 CTRP2 7.8972 11.0381 4.8703 2.3029
HCC1500 CTRP2 7.9142 11.2648 4.7787 2.6136
BT-474 CTRP2 7.9167 9.3966 5.557 0.2701
ZR-75-1 CTRP2 7.9613 9.3012 5.6087 0.1716
ZR-75-30 CTRP2 8.0287 14.1661 3.4945 7.3966
MDA-MB-157 CTRP2 8.0362 9.8352 5.4417 0.459
CAMA-1 CTRP2 8.0452 9.6239 5.5245 0.2868
CAL-51 CTRP2 8.0466 10.8613 5.0289 1.6233
HCC1395 CTRP2 8.1366 10.0569 5.3996 0.5086
HCC1143 CTRP2 8.1658 11.385 4.866 2.0607
HCC1806 CTRP2 8.4215 14.5312 3.5809 6.5296
MCF-7 CTRP2 8.4967 10.0529 5.5425 0.1457
MDA-MB-231 CTRP2 8.5653 10.4991 5.4096 0.3252
HCC202 CTRP2 8.7083 16.405 2.8806 8.8005
HCC1937 CTRP2 8.788 12.1668 4.8545 1.5903
BT-549 CTRP2 9.9005 21.2549 1.363 12.4783
HCC1954 CTRP2 9.9483 22.1957 0.945 13.7404
BT 216 CTRP2 5.4326 6.3479 5.2748 4.6511
BT 416 CTRP2 5.5368 6.0071 5.5002 3.5088
BT 286 CTRP2 5.6414 6.5201 5.4222 3.5137
BT 231 CTRP2 5.7519 9.8347 3.9003 9.5887
BT 131 CTRP2 5.7836 15.8623 0.9165 20.8604
BT 359 CTRP2 5.8054 6.8665 5.4204 3.1239
BT 145 CTRP2 5.8121 6.6359 5.5382 2.6232
BT 482 CTRP2 5.859 6.4864 5.6547 2.0349
BT 232 CTRP2 5.8591 7.6914 5.0618 4.5023
BT 179 CTRP2 5.8627 6.4121 5.6935 1.8677
BT 248 CTRP2 5.8965 7.4629 5.2084 3.8101
BT147 CTRP2 5.9076 6.987 5.4548 2.7556
BT 245 CTRP2 6.0761 8.1252 5.0303 4.202
BT 444 CTRP2 6.2043 7.348 5.5205 1.912
BT 340 CTRP2 6.2123 7.8458 5.2795 2.9052
BT 422 CTRP2 6.2543 7.5216 5.4726 2.0274
BT 172 CTRP2 6.2666 7.881 5.304 2.7088
BT 328 CTRP2 6.3862 7.749 5.4574 1.8805
BT 271 CTRP2 6.761 11.9557 3.6626 8.6905
BT 498 CTRP2 6.9503 8.7982 5.3292 1.6421
BT 320 CTRP2 7.1966 8.5641 5.5659 0.6048
BT 139 CTRP2 7.2018 9.3199 5.2411 1.6899
BT 330 CTRP2 7.2359 10.2733 4.8214 3.2445
BT 504 CTRP2 7.5128 10.6038 4.8412 2.827
BT 112 CTRP2 7.5309 9.0749 5.5162 0.5331
BT 159 CTRP2 7.5454 9.1888 5.4773 0.6284
BT164 CTRP2 7.6764 12.5434 4.0337 5.764
BT 333 CTRP2 7.6905 9.016 5.6069 0.2542
BT 239 CTRP2 7.7596 14.0656 3.3577 8.3246
BT 224 CTRP2 8.0999 10.8054 5.0801 1.4158
BT 187 CTRP2 8.2808 11.273 4.9747 1.6052
BT 440 CTRP2 8.3296 9.9191 5.5278 0.2004
BT 228 CTRP2 10.7621 21.2136 1.9381 9.5002
⏷ Show the Full List of 70 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.8457 8.7018 5.7724 0.0254
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AM-38 CTRP2 -9.3226 33.7232 -22.0287 59.7853
GB-1 CTRP2 5.4643 6.7024 5.1606 5.0111
Hs 683 CTRP2 5.491 6.0471 5.4398 3.866
KNS-60 CTRP2 5.7402 6.1499 5.6786 2.249
SF126 CTRP2 5.9265 7.0647 5.4329 2.8074
KALS-1 CTRP2 5.944 7.1514 5.4051 2.8873
42-MG-BA CTRP2 5.9706 10.2742 3.8677 9.2864
Daoy CTRP2 5.9769 7.495 5.2621 3.4208
SW1088 CTRP2 6.0419 8.243 4.943 4.6343
GaMG CTRP2 6.292 9.2547 4.6406 5.4397
KG-1-C CTRP2 6.4475 13.469 2.6624 13.286
SNU-489 CTRP2 6.5846 7.793 5.5688 1.1653
SF539 CTRP2 6.9289 10.5898 4.46 5.1334
KNS-81 CTRP2 7.0065 9.0927 5.2279 1.959
SF268 CTRP2 7.0239 12.4624 3.6106 8.4623
SNU-738 CTRP2 7.1439 8.8618 5.4121 1.1417
SF295 CTRP2 7.2113 8.8401 5.4575 0.93
SNU-466 CTRP2 7.4115 8.7371 5.5957 0.3968
SNU-1105 CTRP2 7.4229 8.8235 5.5669 0.4624
CCF-STTG1 CTRP2 7.4304 8.5961 5.6576 0.2501
SNU-201 CTRP2 7.4798 8.6843 5.6448 0.257
NMC-G1 CTRP2 7.5059 8.7691 5.6237 0.2902
LN-18 CTRP2 7.5537 8.3952 5.7752 0.0491
U-251MG CTRP2 7.5668 10.873 4.75 3.1087
CAS-1 CTRP2 7.5697 8.95 5.5819 0.3537
GMS-10 CTRP2 7.6223 8.6472 5.7132 0.1038
KNS-42 CTRP2 7.7168 9.4995 5.432 0.6476
DK-MG CTRP2 7.7661 13.4555 3.657 7.1313
A-172 CTRP2 7.8406 11.0994 4.8104 2.5761
Becker CTRP2 7.8512 11.5819 4.5973 3.3524
TM-31 CTRP2 7.866 9.6809 5.4276 0.5753
YH-13 CTRP2 7.8787 10.5024 5.0947 1.5506
D283 Med CTRP2 7.9715 9.4634 5.5542 0.2573
DBTRG-05MG CTRP2 8.0365 11.187 4.8821 2.1258
T98G CTRP2 8.0887 12.2761 4.4225 3.7341
ONS-76 CTRP2 8.0922 9.4496 5.6051 0.1469
YKG-1 CTRP2 8.11 9.4729 5.6035 0.1453
M059K CTRP2 8.1507 14.8865 3.2317 8.2456
LN-229 CTRP2 8.1834 9.7728 5.5244 0.2442
SNB-75 CTRP2 8.1873 15.983 2.7278 10.1207
U-87MG ATCC CTRP2 8.2268 9.4561 5.651 0.0746
U-118MG CTRP2 8.248 9.7134 5.57 0.1603
GOS-3 CTRP2 8.7649 10.5922 5.4523 0.2064
8-MG-BA CTRP2 9.4178 16.7614 3.1682 6.8288
SW1783 CTRP2 10.1826 22.8047 0.8116 13.8321
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP2 5.1878 5.9498 5.1336 5.8942
JHUEM-1 CTRP2 5.2651 8.3486 4.1923 9.4316
HEC-1-A CTRP2 5.5592 7.7674 4.7513 6.4502
JHUEM-3 CTRP2 5.5929 6.9401 5.181 4.6061
EFE-184 CTRP2 6.8253 9.3832 4.9724 3.203
RL95-2 CTRP2 7.3253 9.7722 5.1089 2.0403
MFE-296 CTRP2 7.4621 12.9116 3.7085 7.3747
HEC-265 CTRP2 7.4803 8.4286 5.7375 0.1014
JHUEM-7 CTRP2 7.5075 11.4382 4.4477 4.3558
HEC-108 CTRP2 7.7038 8.9811 5.6249 0.2168
EN CTRP2 7.7093 13.4375 3.6266 7.3348
MFE-319 CTRP2 7.7474 10.1516 5.1762 1.395
HEC-1-B CTRP2 7.958 9.7718 5.4325 0.5165
KLE CTRP2 8.1133 19.4744 0.966 16.4264
HEC-6 CTRP2 8.4225 9.9864 5.5386 0.1649
HEC-251 CTRP2 8.4465 9.9065 5.5749 0.1176
ESS-1 CTRP2 8.4556 13.8899 3.9027 5.2596
HEC-59 CTRP2 8.4761 9.7825 5.6273 0.0658
JHUEM-2 CTRP2 8.6178 10.583 5.3996 0.3263
HEC-50B CTRP2 8.7004 10.44 5.4819 0.181
AN3-CA CTRP2 9.0753 16.6539 3.0028 7.8591
Ishikawa (Heraklio) 02 ER- CTRP2 7.4487 8.5036 5.6989 0.1672
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMRC-3 CTRP2 5.5118 11.163 3.0288 13.6811
UO-31 CTRP2 5.6714 12.1356 2.6826 14.7326
RCC10RGB CTRP2 6.1584 9.6342 4.3436 6.9315
VMRC-RCZ CTRP2 6.4568 10.653 4.0741 7.5152
TUHR10TKB CTRP2 6.9998 9.8188 4.8818 3.3212
TUHR4TKB CTRP2 7.6889 8.9731 5.622 0.2268
CAL-54 CTRP2 7.714 12.5365 4.0622 5.5996
BFTC-909 CTRP2 7.8417 9.0661 5.6472 0.1447
KMRC-20 CTRP2 7.9446 11.7715 4.5668 3.3595
786-O CTRP2 8.0853 15.3218 2.9768 9.3237
TUHR14TKB CTRP2 8.2268 10.2914 5.3481 1.2565
SNU-1272 CTRP2 8.4162 9.7779 5.6081 0.0889
VMRC-RCW CTRP2 8.5361 15.3517 3.2675 7.5749
769-P CTRP2 8.6486 11.9006 4.8963 1.566
OS-RC-2 CTRP2 8.6671 10.3904 5.487 0.1813
KMRC-1 CTRP2 10.5377 18.7741 2.9196 6.4456
KMRC-2 CTRP2 10.7045 19.8114 2.5476 7.5289
Caki-2 CTRP2 12.3352 22.9863 2.0637 7.4028
ACHN CTRP2 12.4881 23.9714 1.7109 8.3354
Caki-1 CTRP2 14.8299 30.701 0.0397 10.7367
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LS123 CTRP2 4.2301 6.6368 3.876 13.3615
SNU-407 CTRP2 4.6539 5.9588 4.5494 9.6268
C2BBe1 CTRP2 4.9958 7.6975 4.2378 9.8938
LS1034 CTRP2 5.2625 6.1904 5.1471 5.6197
CL-11 CTRP2 5.4232 6.9338 5.0152 5.6962
NCI-H747 CTRP2 5.7037 8.9493 4.2991 8.0206
SNU-C5 CTRP2 5.9849 7.2522 5.3903 2.8664
T84 CTRP2 6.0723 11.5803 3.2996 11.4422
SW1417 CTRP2 6.7706 11.6736 3.8098 8.0683
RKO CTRP2 6.9162 10.3838 4.5513 4.7795
SNU-1033 CTRP2 7.3077 21.3729 -0.5941 22.3289
SNU-C1 CTRP2 7.3136 12.3623 3.8705 6.9467
DLD-1 CTRP2 7.395 8.2647 5.7636 0.0855
SW948 CTRP2 7.4007 9.9533 5.0712 2.0966
SNU-61 CTRP2 7.4023 11.8245 4.1927 5.5158
HCC-56 CTRP2 7.4646 8.7727 5.605 0.3492
HT-55 CTRP2 7.5654 10.3821 4.9737 2.2755
SNU-503 CTRP2 7.5798 12.3319 4.0699 5.7552
LS513 CTRP2 7.6145 12.933 3.8046 6.7639
HT-29 CTRP2 7.6436 9.0677 5.5682 0.3515
HCT 8 CTRP2 7.6844 13.0889 3.7775 6.7709
COLO 678 CTRP2 7.7002 11.3725 4.6013 3.5154
LS411N CTRP2 7.7062 9.3712 5.478 0.5341
SW48 CTRP2 7.7082 12.8409 3.9128 6.1991
HT115 CTRP2 7.8193 9.4359 5.5022 0.4206
RCM-1 [Human ESC] CTRP2 7.8868 9.3215 5.5727 0.2514
SNU-C4 CTRP2 7.8914 9.1115 5.6496 0.1306
KM12 CTRP2 8.0005 9.826 5.43 0.5021
NCI-H716 CTRP2 8.0096 13.4908 3.8041 6.2122
COLO205 CTRP2 8.0129 9.1293 5.6869 0.0696
OUMS-23 CTRP2 8.0779 9.0544 5.7341 0.0303
CCK-81 CTRP2 8.1285 9.9859 5.4233 0.4593
NCI-H508 CTRP2 8.1296 9.5826 5.572 0.1843
COLO 320 CTRP2 8.1305 14.8287 3.2457 8.2205
GP2d CTRP2 8.1477 9.5568 5.5879 0.1578
MDST8 CTRP2 8.1566 9.4966 5.6122 0.1253
HCT 116 CTRP2 8.2225 9.6233 5.5921 0.1372
SK-CO-1 CTRP2 8.2339 9.8157 5.5284 0.2238
LS180 CTRP2 8.2427 9.8816 5.5081 0.2542
COLO201 CTRP2 8.4457 9.7548 5.6262 0.0699
LoVo CTRP2 8.5524 10.3486 5.459 0.2476
SW620 CTRP2 8.6432 10.2943 5.5118 0.1551
HCT 15 CTRP2 8.6926 10.105 5.5936 0.069
CW-2 CTRP2 8.9279 10.4879 5.5462 0.0808
SNU-C2A CTRP2 9.4823 23.7053 -0.1107 17.5179
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-6 CTRP2 4.4305 6.601 4.105 11.9253
SNU-761 CTRP2 4.6123 5.8764 4.5239 9.8466
JHH-5 CTRP2 5.279 8.681 4.0442 10.0106
JHH-4 CTRP2 6.5076 11.5827 3.6512 9.1814
Li-7 CTRP2 6.5741 14.6369 2.1812 14.8931
JHH-6 CTRP2 6.6834 8.1039 5.4859 1.3629
SNU-449 CTRP2 6.9489 13.9993 2.7933 11.8669
SNU-398 CTRP2 7.5758 10.4064 4.9688 2.2822
SK-HEP-1 CTRP2 7.6352 8.826 5.6545 0.1869
JHH-1 CTRP2 7.7151 8.8618 5.6721 0.298
HuH-1 CTRP2 7.8773 9.2081 5.6101 0.1911
Hep-G2 CTRP2 7.9072 9.2096 5.6209 0.1669
SNU-182 CTRP2 8.0927 23.7316 -1.1555 22.4031
HLF CTRP2 8.1045 15.4449 2.9306 9.4723
Hep 3B2.1-7 CTRP2 8.1543 9.5869 5.5797 0.1676
SNU-423 CTRP2 8.1606 9.8347 5.4929 0.3063
JHH-2 CTRP2 8.6878 16.4216 2.8591 8.9091
PLC/PRF/5 CTRP2 8.9452 14.8917 3.7408 5.2848
SNU-387 CTRP2 11.972 23.395 1.6698 8.9977
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 139 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1666 CTRP2 4.1907 6.1973 3.9777 13.1005
NCI-H211 CTRP2 4.6547 7.1525 4.1283 11.213
NCI-H2087 CTRP2 4.662 6.6107 4.3505 10.3382
SK-MES-1 CTRP2 4.8903 6.8938 4.4824 9.1984
NCI-H446 CTRP2 5.0417 6.2345 4.8929 7.2096
NCI-H810 CTRP2 5.1956 7.2133 4.6591 7.6992
DV-90 CTRP2 5.2317 7.7861 4.4293 8.5396
NCI-H2029 CTRP2 5.2483 6.5449 5.0016 6.2105
PC-14 CTRP2 5.2563 6.5763 4.9974 6.2052
NCI-H647 CTRP2 5.3478 11.2009 2.8648 14.691
T3M-10 CTRP2 5.3577 10.1971 3.3713 12.6137
Calu-3 CTRP2 5.3595 6.7815 5.0183 5.8473
SW1271 CTRP2 5.3958 7.0714 4.9249 6.1281
NCI-H1105 CTRP2 5.4109 6.2049 5.3034 4.605
COLO 668 CTRP2 5.4245 6.2481 5.3031 4.5669
NCI-H1693 CTRP2 5.4452 8.476 4.2992 8.5802
LCLC-97TM1 CTRP2 5.4588 6.9356 5.0501 5.4665
NCI-H1944 CTRP2 5.4757 6.4941 5.2618 4.5828
LK2 CTRP2 5.4989 5.8487 5.4889 3.6682
ChaGo-K-1 CTRP2 5.5252 6.4604 5.3277 4.1927
HCC44 CTRP2 5.5385 9.0758 4.0889 9.2497
NCI-H522 CTRP2 5.5679 6.4412 5.3803 3.8722
NCI-H2228 CTRP2 5.5877 6.4938 5.3785 3.827
NCI-H1694 CTRP2 5.5894 6.4509 5.3986 3.7434
RERF-LC-A1 CTRP2 5.6482 7.456 4.9863 5.2764
LUDLU-1 CTRP2 5.6483 6.3615 5.4977 3.1984
NCI-H1155 CTRP2 5.7092 6.9027 5.3116 3.7946
NCI-H2106 CTRP2 5.71 7.5287 5.008 5.0476
Sq-1 CTRP2 5.7109 7.5661 4.9904 5.119
NCI-H1581 CTRP2 5.7364 7.9195 4.8392 5.6934
NCI-H322 CTRP2 5.7967 7.3659 5.1674 4.194
NCI-H1355 CTRP2 5.8073 7.8176 4.9532 5.0659
EKVX CTRP2 5.8682 13.1055 2.3659 15.5638
NCI-H2081 CTRP2 5.9553 10.645 3.6694 10.143
NCI-H1650 CTRP2 5.9727 8.1652 4.9237 4.8511
DMS 454 CTRP2 5.9794 9.6993 4.1625 8.035
NCI-H1793 CTRP2 5.9864 7.003 5.5159 2.336
NCI-H358 CTRP2 6.0422 7.3461 5.3917 2.7478
DMS 53 CTRP2 6.0561 8.986 4.5833 6.1187
NCI-H2170 CTRP2 6.0653 8.1699 4.999 4.3542
NCI-H520 CTRP2 6.095 7.6795 5.2686 3.1646
Lu-99 CTRP2 6.1821 7.1696 5.5921 1.6515
KNS-62 CTRP2 6.2294 7.5371 5.4461 2.1798
NCI-H1703 CTRP2 6.2694 13.5942 2.4553 14.4286
NCI-H1975 CTRP2 6.2911 7.9248 5.301 2.6795
SBC-5 CTRP2 6.3292 8.0791 5.2536 2.8131
NCI-H2444 CTRP2 6.3961 8.5685 5.0621 3.4979
NCI-H226 CTRP2 6.4219 8.1445 5.2899 2.5129
RERF-LC-Ad1 CTRP2 6.4256 8.0404 5.3435 2.2867
HARA [Human squamous cell lung carcinoma] CTRP2 6.4842 8.2956 5.261 2.5349
HCC1195 CTRP2 6.5192 7.9332 5.4603 1.6757
HCC15 CTRP2 6.5285 9.5627 4.6706 4.9047
COR-L88 CTRP2 6.7775 9.3787 4.9416 3.397
HCC2935 CTRP2 6.8049 11.4749 3.934 7.4983
NCI-H889 CTRP2 6.8661 14.1763 2.6413 12.6059
NCI-H1915 CTRP2 6.9307 11.2855 4.1208 6.5231
HCC1171 CTRP2 7.0474 10.5717 4.5523 4.5794
NCI-H292 CTRP2 7.1256 12.0658 3.8803 7.1984
NCI-H2171 CTRP2 7.1401 11.7088 4.0653 6.4213
BEN CTRP2 7.171 8.0999 5.7369 0.1896
MOR/CPR CTRP2 7.2627 8.2448 5.7202 0.1889
NCI-H526 CTRP2 7.3131 13.0515 3.5337 8.3083
NCI-H2286 CTRP2 7.4997 9.4239 5.358 1.0139
NCI-H1341 CTRP2 7.6077 13.2268 3.6578 7.3598
NCI-H1573 CTRP2 7.6248 11.6564 4.4208 4.3075
NCI-H1568 CTRP2 7.6897 11.7418 4.4223 4.2181
HCC1588 CTRP2 7.6944 12.6004 4.0186 5.7991
NCI-H2172 CTRP2 7.7279 12.3346 4.1674 5.1657
HCC366 CTRP2 7.7314 11.9748 4.3397 4.4863
DMS 273 CTRP2 7.7752 9.3571 5.5135 0.4149
NCI-H2122 CTRP2 7.7856 9.6128 5.4183 0.6437
NCI-H1092 CTRP2 7.8049 12.3103 4.229 4.8226
HCC4006 CTRP2 7.8199 9.3455 5.5367 0.3454
NCI-H460 CTRP2 7.8494 9.6512 5.4318 0.5735
VMRC-LCD CTRP2 7.8529 13.158 3.8584 6.2129
A-549 CTRP2 7.8679 12.4254 4.2155 4.7941
SHP-77 CTRP2 7.8718 10.1284 5.2493 1.067
Calu-6 CTRP2 7.8735 11.8779 4.4745 3.7904
LC-1/sq-SF CTRP2 7.8736 9.1736 5.621 0.1752
NCI-H1435 CTRP2 7.9237 9.9042 5.3653 0.7036
NCI-H1734 CTRP2 7.9272 9.9592 5.3449 0.756
NCI-H1755 CTRP2 7.9279 9.6994 5.4475 0.4959
DMS 79 CTRP2 7.9412 10.0615 5.3102 0.8427
NCI-H2126 CTRP2 7.9549 9.6401 5.4817 0.4065
NCI-H2196 CTRP2 7.9666 9.4771 5.5472 0.2714
RERF-LC-MS CTRP2 7.9818 13.4584 3.8011 6.2617
NCI-H2291 CTRP2 8.003 11.7086 4.6302 3.0596
IA-LM CTRP2 8.0045 11.5997 4.6803 2.875
NCI-H196 CTRP2 8.0185 11.9385 4.5348 3.3949
NCI-H2085 CTRP2 8.037 9.8536 5.435 0.4737
CAL-12T CTRP2 8.0668 9.8947 5.4319 0.4672
COLO 699 CTRP2 8.0683 15.0135 3.114 8.8199
NCI-H69 CTRP2 8.0862 9.7542 5.4928 0.3323
NCI-H1838 CTRP2 8.0914 10.9183 5.0278 1.5892
LCLC-103H CTRP2 8.1041 9.3396 5.6475 0.0949
NCI-H1395 CTRP2 8.1103 15.8176 2.754 10.1367
NCI-H841 CTRP2 8.1209 11.1565 4.9411 1.8487
NCI-H1373 CTRP2 8.1263 11.5378 4.7773 2.4037
LOU-NH91 CTRP2 8.1879 9.7643 5.5292 0.2351
HCC78 CTRP2 8.1986 9.7608 5.5346 0.2236
HCC827 CTRP2 8.2348 15.4099 3.0374 8.8728
NCI-H441 CTRP2 8.2644 11.6211 4.8166 2.1385
NCI-H1563 CTRP2 8.2714 9.9707 5.4869 0.2815
HCC1438 CTRP2 8.3105 13.1044 4.1766 4.3991
COR-L95 CTRP2 8.3152 9.7132 5.5945 0.1178
HCC2108 CTRP2 8.3157 9.8903 5.5328 0.1965
NCI-H838 CTRP2 8.332 14.5629 3.5075 6.9295
NCI-H650 CTRP2 8.3402 10.2161 5.4241 0.3739
NCI-H2110 CTRP2 8.3404 15.1848 3.217 8.0351
HCC95 CTRP2 8.3597 9.813 5.576 0.131
LXF 289 CTRP2 8.3893 11.1592 5.0761 1.215
HOP-92 CTRP2 8.4027 36.0853 -7.0587 31.8313
Lu-65 CTRP2 8.4048 14.5187 3.5759 6.5704
NCI-H2030 CTRP2 8.4755 10.0806 5.5251 0.1715
NCI-H1184 CTRP2 8.4858 10.183 5.4928 0.2137
EBC-1 CTRP2 8.5091 10.4154 5.418 0.328
NCI-H1623 CTRP2 8.5099 13.6928 4.0273 4.7256
NCI-H2023 CTRP2 8.5288 10.2434 5.4875 0.2111
NCI-H23 CTRP2 8.5341 14.4617 3.6855 5.9862
NCI-H1869 CTRP2 8.5414 10.8389 5.2727 0.6118
NCI-H727 CTRP2 8.55 13.2633 4.2475 3.8656
SK-LU-1 CTRP2 8.6127 10.3597 5.4777 0.2055
NCI-H2009 CTRP2 8.6272 10.3423 5.4892 0.1867
NCI-H661 CTRP2 8.7079 10.4548 5.4795 0.1826
NCI-H2342 CTRP2 8.7273 10.5697 5.4463 0.2233
COR-L105 CTRP2 8.8007 12.2552 4.824 1.6732
NCI-H1339 CTRP2 8.9349 14.4977 3.9146 4.659
HOP-62 CTRP2 8.9462 17.3528 2.5874 9.5571
EPLC-272H CTRP2 9.0036 19.1876 1.7456 12.4604
NCI-H1299 CTRP2 9.046 10.8445 5.4666 0.1376
NCI-H2405 CTRP2 9.0567 11.0912 5.3849 0.2339
Calu-1 CTRP2 9.2442 16.0508 3.3897 6.2269
NCI-H1792 CTRP2 9.4355 16.0107 3.5234 5.5226
HCC2279 CTRP2 9.5985 18.8032 2.328 9.6155
SW1573 CTRP2 9.8439 22.421 0.7655 14.439
DMS 114 CTRP2 10.4253 21.7381 1.4792 11.4129
HCC1833 CTRP2 11.1452 22.3032 1.6705 9.9191
RERF-LC-Ad2 CTRP2 13.3782 25.5437 1.5155 8.0514
Hs 888.Lu CTRP2 8.0964 10.6191 5.1563 1.1841
⏷ Show the Full List of 139 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 7.1671 8.219 5.6902 0.2918
P-STS CTRP2 7.4952 9.3727 5.3773 0.9569
SYO-1 CTRP2 7.9753 10.1041 5.3089 0.8248
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 7.5027 9.2536 5.4306 0.7898
Yamato-SS CTRP2 7.5399 8.6402 5.6848 0.1643
A-204 CTRP2 4.9249 7.5328 4.2414 10.0584
GCT CTRP2 5.1585 7.1941 4.6302 7.9094
HT-1080 CTRP2 5.4727 5.9613 5.441 3.9182
G-401 CTRP2 5.6959 11.0216 3.2597 12.3572
MES-SA CTRP2 5.8433 6.5505 5.609 2.2593
TE 441.T CTRP2 6.0812 7.6912 5.2515 3.2625
TE 617.T CTRP2 6.7181 12.8181 3.2013 10.6468
G-402 CTRP2 6.8577 12.8727 3.2821 10.0764
BT-12 CTRP2 7.0894 7.9392 5.7636 0.1673
KYM-1 CTRP2 7.1566 10.4803 4.6709 3.9464
Hs 729.T CTRP2 7.2425 12.7052 3.6521 7.9415
RD CTRP2 7.5127 12.4687 3.9583 6.297
SW982 CTRP2 7.6563 9.4588 5.4202 0.7168
Rh41 CTRP2 7.7622 13.3714 3.6948 6.9873
Rh18 CTRP2 7.8274 9.4875 5.4858 0.4542
BT-16 CTRP2 7.8443 9.0667 5.6479 0.1431
RKN CTRP2 7.9276 9.2358 5.6192 0.1643
TTC-709 CTRP2 8.3076 9.9769 5.4987 0.2511
SK-UT-1 CTRP2 8.4131 12.2404 4.6267 2.6509
Tm87-16 CTRP2 8.863 20.3106 1.102 14.8097
SK-LMS-1 CTRP2 9.0449 16.7739 2.9267 8.1789
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.6637 9.153 5.5441 0.3964
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 8.3081 10.6637 5.2383 0.8161
TYK-nu CTRP2 4.7798 6.0543 4.6616 8.8387
COV434 CTRP2 4.857 8.2436 3.8471 11.8149
A2780 CTRP2 4.9374 6.3292 4.7481 8.0526
OAW42 CTRP2 5.6372 6.2011 5.5491 3.0313
SNU-119 CTRP2 5.7127 6.5995 5.4581 3.1896
EFO-21 CTRP2 5.7969 7.042 5.3268 3.5307
COV362 CTRP2 5.8498 7.8255 4.9869 4.8355
EFO-27 CTRP2 6.0116 8.7024 4.688 5.7648
TOV-112D CTRP2 6.0181 7.0191 5.5349 2.1929
SNU-840 CTRP2 6.4946 9.9432 4.4563 5.8548
OV7 CTRP2 7.4761 9.1343 5.4667 0.7027
DOV13 CTRP2 7.4802 9.1485 5.4629 0.711
ES2 CTRP2 7.5361 9.8076 5.2124 1.4607
OVCAR-5 CTRP2 7.6305 12.3185 4.1104 5.5236
COV644 CTRP2 7.7488 15.3202 2.7389 10.7511
OVTOKO CTRP2 7.7804 10.218 5.1651 1.4035
ONCO-DG-1 CTRP2 7.9359 9.5012 5.526 0.3224
OVISE CTRP2 7.9475 9.8281 5.406 0.5859
MCAS CTRP2 7.9549 10.474 5.1462 1.3218
FU-OV-1 CTRP2 7.9652 11.606 4.6544 3.0121
SNU-8 CTRP2 7.9729 9.0878 5.687 0.0747
OV56 CTRP2 8.0488 8.9903 5.7454 0.0264
Caov-3 CTRP2 8.0709 9.7442 5.4904 0.3427
OVSAHO CTRP2 8.0757 9.4485 5.5993 0.1582
IGROV-1 CTRP2 8.1039 10.7421 5.1087 1.3233
OVK18 CTRP2 8.1651 10.0216 5.4251 0.4398
JHOC-5 CTRP2 8.1886 9.4772 5.6304 0.0996
JHOS-2 CTRP2 8.2584 12.7016 4.3299 3.8857
JHOM-1 CTRP2 8.2636 9.4465 5.6669 0.0577
OC 314 CTRP2 8.3546 13.4548 4.0419 4.855
OVCAR-4 CTRP2 8.4106 11.3422 5.0109 1.3936
OVCAR-8 CTRP2 8.438 11.4991 4.9591 1.5315
OAW28 CTRP2 8.4879 11.051 5.1662 0.9021
SK-OV-3 CTRP2 8.4926 10.0693 5.5353 0.1551
RMG-I CTRP2 8.681 10.7912 5.3483 0.3983
HEY A8 CTRP2 9.1472 15.5281 3.5711 5.6757
OV-90 CTRP2 9.4303 16.6425 3.2308 6.5869
Kuramochi CTRP2 10.604 23.1749 0.916 12.9545
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 CTRP2 6.6497 9.3213 4.8789 3.8469
MSTO-211H CTRP2 6.7967 14.9895 2.1823 14.4787
ACC-MESO-1 CTRP2 7.6612 8.9536 5.6182 0.2431
MPP 89 CTRP2 8.0706 9.6556 5.523 0.2813
NCI-H28 CTRP2 8.2363 11.611 4.8057 2.2009
NCI-H2052 CTRP2 8.3853 10.3301 5.4 0.4046
JL-1 CTRP2 8.6152 13.8212 4.0322 4.5857
IST-Mes1 CTRP2 9.1217 18.218 2.2917 10.3824
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 CTRP2 4.9873 34.6514 -9.1493 38.5592
LNCaP clone FGC CTRP2 4.9885 7.4323 4.351 9.4583
PaCa-3 CTRP2 5.9434 6.5898 5.6835 1.7238
DU145 CTRP2 7.1907 11.9967 3.9611 6.7678
VCaP CTRP2 7.6289 12.0134 4.2546 4.9548
22Rv1 CTRP2 9.9506 19.8886 2.0441 10.1441
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 5.8308 8.579 4.595 6.5175
YD-15 CTRP2 7.9527 14.6799 3.195 8.6756
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1 CTRP2 4.7549 10.1013 2.8616 16.037
ECC10 CTRP2 4.8658 5.9983 4.7705 8.1841
HGC-27 CTRP2 4.8821 6.4617 4.6417 8.6107
SNU-16 CTRP2 5.1451 6.8904 4.7499 7.4698
Hs 746.T CTRP2 5.4959 6.8298 5.1356 5.0298
SH-10-TC CTRP2 5.5506 6.1416 5.4761 3.555
MKN7 CTRP2 5.6676 14.1808 1.658 18.5935
GSU CTRP2 7.0511 7.8128 5.7947 0.1232
MKN45 CTRP2 7.2408 8.1144 5.7591 0.1275
MKN1 CTRP2 7.6265 9.5931 5.3507 0.9398
NUGC-3 CTRP2 7.6365 9.7957 5.2706 1.1819
ECC12 CTRP2 7.6646 8.7798 5.6823 0.1362
GSS CTRP2 7.7317 11.7214 4.4587 4.0244
SNU-620 CTRP2 7.7993 9.0767 5.6274 0.1848
SNU-668 CTRP2 7.8415 10.0554 5.2647 1.0426
HuG1-N CTRP2 7.89 14.9456 3.0224 9.4398
SNU-5 CTRP2 7.9009 10.3193 5.184 1.2455
IM95 CTRP2 7.9383 11.1363 4.8498 2.3343
MKN74 CTRP2 7.975 12.6714 4.1684 4.8396
SNU-601 CTRP2 7.9776 11.2376 4.827 2.3759
NUGC-4 CTRP2 7.9883 14.1858 3.4576 7.5982
Fu97 CTRP2 8.1528 9.7914 5.5057 0.2856
KE-39 CTRP2 8.2181 14.7289 3.3528 7.6822
AGS CTRP2 8.2534 9.7273 5.5671 0.1629
KATO III CTRP2 8.2595 9.8198 5.5367 0.2046
SNU-719 CTRP2 8.2714 10.595 5.2489 0.8093
23132/87 CTRP2 8.3907 9.5874 5.6632 0.0485
SNU-216 CTRP2 8.3935 14.6197 3.5208 6.7965
NCI-N87 CTRP2 8.7185 10.8759 5.3321 0.4159
LMSU CTRP2 11.3936 22.0525 1.9369 8.7822
SNG-M CTRP2 7.2118 10.6966 4.6046 4.1347
SNU-685 CTRP2 8.1073 11.7668 4.6646 2.8234
SNU-1077 CTRP2 8.153 11.8609 4.6486 2.8331
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 5.3764 5.8733 5.3539 4.527
FTC-133 CTRP2 6.2023 7.7963 5.2963 2.8528
8505C CTRP2 6.5527 9.3458 4.7958 4.3451
ML-1 [Human leukemia] CTRP2 6.8261 8.7882 5.2564 2.0724
TT2609-C02 CTRP2 6.9916 9.9772 4.8004 3.6583
BHT-101 CTRP2 7.7157 9.1642 5.5618 0.3349
CAL-62 CTRP2 7.8828 9.2673 5.5908 0.221
B-CPAP CTRP2 7.91 9.3769 5.5615 0.264
8305C CTRP2 7.9225 9.4185 5.5512 0.2788
FTC-238 CTRP2 8.1755 16.8089 2.3182 11.6651
TT CTRP2 8.2165 9.8668 5.5033 0.2701
CGTH-W-1 CTRP2 8.4277 9.7066 5.6361 0.0641
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-25 CTRP2 4.6048 6.7395 4.2408 10.9163
YD-8 CTRP2 5.0416 6.249 4.888 7.2282
PE/CA-PJ15 CTRP2 5.6401 9.1287 4.1536 8.763
BICR 6 CTRP2 5.8143 6.4541 5.6263 2.2585
FaDu CTRP2 5.8789 12.4905 2.6824 14.3103
HSC-2 CTRP2 5.9074 8.9161 4.4929 6.7908
HSC-4 CTRP2 6.5602 9.8289 4.563 5.2994
CAL-33 CTRP2 6.7137 10.7127 4.2419 6.3764
SCC-4 CTRP2 6.7336 8.4867 5.3388 1.8696
PE/CA-PJ34 (clone C12) CTRP2 7.1732 9.5771 5.1066 2.2218
SCC-9 CTRP2 7.2581 12.5596 3.7345 7.583
PE/CA-PJ41 (clone D2) CTRP2 7.3294 15.763 2.21 13.437
CAL-27 CTRP2 7.5483 14.645 2.924 10.3542
PE/CA-PJ49 CTRP2 7.6592 13.2174 3.6982 7.1232
YD-10B CTRP2 7.7187 9.1904 5.5532 0.3521
HSC-3 CTRP2 7.7439 9.098 5.598 0.2526
SNU-1076 CTRP2 7.7589 9.1229 5.5948 0.2534
SNU-1066 CTRP2 7.8728 11.7893 4.515 3.6375
BICR 16 CTRP2 7.9773 9.7815 5.4371 0.4964
SNU-899 CTRP2 8.0382 11.4098 4.7846 2.4651
SNU-1214 CTRP2 8.2196 11.535 4.8298 2.1343
BICR 18 CTRP2 8.2552 9.8282 5.532 0.2126
SNU-1041 CTRP2 8.318 11.6885 4.8161 2.0916
BICR 22 CTRP2 8.3686 9.8201 5.5768 0.1286
BHY CTRP2 8.4907 10.1743 5.4977 0.2054
BICR 56 CTRP2 8.5008 10.1051 5.5258 0.1654
Detroit 562 CTRP2 8.5904 10.1852 5.5305 0.1428
BICR 31 CTRP2 8.8189 15.2746 3.4857 6.385
SNU-46 CTRP2 10.2566 23.3238 0.613 14.3323
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2 1.9775 11.4099 -5.7038 16.0206
TCCSUP CTRP2 5.5743 6.4072 5.4012 3.7735
SW1710 CTRP2 5.6652 10.415 3.5356 11.2845
BC-3C CTRP2 5.9923 9.978 4.034 8.5485
U-BLC1 CTRP2 5.9933 11.4302 3.3088 11.5585
BFTC-905 CTRP2 6.1132 7.2784 5.4838 2.2269
UM-UC-3 CTRP2 6.3307 8.7777 4.9084 4.2502
T24 CTRP2 6.4591 9.3219 4.7371 4.7446
253J-BV CTRP2 6.4776 8.7119 5.0522 3.4054
KU-19-19 CTRP2 7.5096 8.8357 5.6 0.3399
KMBC-2 CTRP2 7.5895 13.7885 3.3723 8.5244
253J CTRP2 7.8268 9.1866 5.5983 0.2251
5637 CTRP2 7.8881 12.2897 4.2919 4.4723
RT-112 CTRP2 7.9759 9.3688 5.5901 0.196
639V CTRP2 8.0404 9.0021 5.7387 0.0303
J82 CTRP2 8.061 12.3021 4.3937 3.8741
RT-4 CTRP2 8.1002 11.4344 4.8085 2.3202
JMSU-1 CTRP2 8.1327 9.5817 5.5735 0.1813
VM-CUB-1 CTRP2 8.2379 13.4915 3.9515 5.343
647V CTRP2 8.2768 15.7268 2.9137 9.2841
HT-1376 CTRP2 8.4556 10.3772 5.4109 0.3585
UM-UC-1 CTRP2 9.362 17.1144 2.9695 7.6193
SCaBER CTRP2 9.3665 17.28 2.895 7.8844
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.5666 8.4817 5.7504 0.0708

References

1 Antiviral therapies with phospholipase D inhibitors. US9453017.