Details of the Drug

General Information of Drug (ID: DMNH6F5)

• Drug Name: Gca-186
• Synonyms: gca-186; I-EBU-dM; 6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPYLURACIL; CHEMBL319139; CHEBI:42702; 6-(3,5-dimethylbenzyl)-1-(ethoxymethyl)-5-isopropyluracil; 6-(3,5-dimethylbenzyl)-1-(ethoxymethyl)-5-(1-methylethyl)uracil; 6-(3,5-dimethylbenzyl)-1-(ethoxymethyl)-5-(propan-2-yl)pyrimidine-2,4(1H,3H)-dione; 6-(3,5-dimethylbenzyl)-1-(ethoxymethyl)-5-(1-methylethyl)pyrimidine-2,4(1H,3H)-dione; AC1L1FZB; CTK6G4092; BDBM50032238; DB07820; 6-(3,5-Dimethylbenzyl)-1-(ethoxymethyl])-5-isopropyluracil

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus infection	1C62	Clinical trial	[1]

• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C19H26N2O3
  Canonical SMILES: CCOCN1C(=C(C(=O)NC1=O)C(C)C)CC2=CC(=CC(=C2)C)C
  InChI: InChI=1S/C19H26N2O3/c1-6-24-11-21-16(10-15-8-13(4)7-14(5)9-15)17(12(2)3)18(22)20-19(21)23/h7-9,12H,6,10-11H2,1-5H3,(H,20,22,23)
  InChIKey: NVGVZWUORYLPAL-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 3457
  ChEBI ID: CHEMBL42702
  CAS Number: 149950-61-8
  DrugBank ID: DB07820
  TTD ID: D08KMU
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

References

• [1] Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.