Details of the Drug

General Information of Drug (ID: DMNSJ3C)

Drug Name
JNJ-26854165
Synonyms
Serdemetan; 881202-45-5; N1-(2-(1H-Indol-3-yl)ethyl)-N4-(pyridin-4-yl)benzene-1,4-diamine; JNJ-26854165 (Serdemetan); UNII-ID6YB4W3V8; ID6YB4W3V8; C21H20N4; n-(2-(1h-indol-3-yl)ethyl)-n'-(4-pyridinyl)-1,4-benzenediamine; N-[2-(1H-INDOL-3-YL)ETHYL]-N'-(4-PYRIDINYL)-1,4-BENZENEDIAMINE; Serdemetan [INN]; MLS006011022; SCHEMBL3012498; CHEMBL2137530; CTK8C1936; EX-A267; DTXSID30236830; MolPort-009-679-468; HMS3654A16; JNJ 26854165 (Serdemetan); BCP02124; AOB87702; QC-534; ANW-67474
Indication
Disease Entry ICD 11 Status REF
Non-small-cell lung cancer 2C25.Y Phase 1 [1]
Prostate cancer 2C82.0 Phase 1 [1]
Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 328.4
Logarithm of the Partition Coefficient (xlogp) 4.6
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C21H20N4
IUPAC Name
1-N-[2-(1H-indol-3-yl)ethyl]-4-N-pyridin-4-ylbenzene-1,4-diamine
Canonical SMILES
C1=CC=C2C(=C1)C(=CN2)CCNC3=CC=C(C=C3)NC4=CC=NC=C4
InChI
InChI=1S/C21H20N4/c1-2-4-21-20(3-1)16(15-24-21)9-14-23-17-5-7-18(8-6-17)25-19-10-12-22-13-11-19/h1-8,10-13,15,23-24H,9,14H2,(H,22,25)
InChIKey
CEGSUKYESLWKJP-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11609586
CAS Number
881202-45-5
UNII
ID6YB4W3V8
DrugBank ID
DB12027
TTD ID
D0B3GF
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ubiquitin-protein ligase E3 Mdm2 (MDM2) TT08GJW MDM2_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Non-small-cell lung cancer
ICD Disease Classification 2C25.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Ubiquitin-protein ligase E3 Mdm2 (MDM2) DTT MDM2 8.31E-13 0.12 0.44
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 2.6725 8.392 0.2272 20.8486
SK-N-MC CTRP2 0.3627 1.9054 0.3609 31.1963
SK-PN-DW GDSC2 1.1402 3.6911 0.8308 23.5352
MHH-ES-1 GDSC1; GDSC2; CTRP2 1.4574 4.1551 1.3318 24.3256
SK-ES-1 GDSC1; GDSC2; CTRP2 1.6341 4.5081 1.4542 23.3384
Hs 888.T CTRP2 1.8006 5.8834 1.2443 23.58
A-673 GDSC1; GDSC2; CTRP2 2.0179 4.2021 1.9275 20.4709
U2OS GDSC1; GDSC2; CTRP2; CTRP1 2.1846 4.5851 2.0376 19.636
ES1 GDSC1; GDSC2 2.5958 6.2122 1.2346 15.4299
ES7 GDSC1; GDSC2 2.5978 4.6462 1.9898 10.8058
TC-71 GDSC1; GDSC2 2.6317 5.996 1.3737 14.4645
ES8 GDSC1; GDSC2 2.662 5.6039 1.5931 13.016
EW-16 GDSC1; GDSC2 2.6632 6.2365 1.2849 14.896
EW-12 GDSC2 3.1566 6.9629 1.3619 12.8384
CHSA0108 GDSC1; GDSC2 3.2061 6.7096 1.5307 11.6493
HuO9 GDSC1; GDSC2 3.2251 8.2117 0.7959 15.9848
NOS-1 [Human HNSCC] GDSC1; GDSC2 3.3171 7.8294 1.0642 14.1481
EW-22 GDSC1; GDSC2 3.4371 9.8144 0.1712 18.7264
EW-7 GDSC1; GDSC2 3.4767 11.0206 -0.3992 21.3523
CADO-ES1 GDSC1; GDSC2 3.5719 6.0571 2.1567 6.6808
EW-3 GDSC1; GDSC2 3.6283 6.8665 1.798 8.7801
ES4 GDSC1; GDSC2 3.7296 6.6621 1.9782 7.3881
HuO-3N1 GDSC1; GDSC2 3.8215 7.5515 1.6076 9.4499
U-CH2 GDSC2 3.9266 8.1756 1.3788 10.5715
CHSA8926 GDSC1; GDSC2 3.9311 6.2154 2.3461 4.6157
CAL-72 GDSC1; GDSC2 3.9904 7.0793 1.967 6.8124
EW-1 GDSC1; GDSC2 4.0207 8.0184 1.5275 9.4323
EW-13 GDSC1; GDSC2 4.0493 5.9541 2.5515 3.1244
EW-11 GDSC1; GDSC2 4.051 7.4966 1.8066 7.6538
ES6 GDSC1; GDSC2 4.0991 7.2954 1.9398 6.7246
EW-18 GDSC1; GDSC2 4.1026 7.3279 1.9264 6.7985
H-EMC-SS GDSC1; GDSC2 4.1112 7.6652 1.7678 7.7478
EW-24 GDSC1; GDSC2 4.2189 6.6717 2.3226 4.1445
ES5 GDSC1; GDSC2 4.3217 7.9306 1.7882 7.1395
TC71 CTRP2 4.5789 7.4573 3.431 7.7371
NY GDSC1; GDSC2 4.6956 9.4108 1.3324 9.01
SaOS-2 GDSC1; GDSC2; CTRP2 4.8815 8.2131 3.3223 7.5587
Hs 822.T CTRP2 4.9008 6.5574 4.1651 3.9827
SW1353 CTRP2 4.9058 7.0373 3.9302 4.9581
SJSA-1 GDSC1; GDSC2; CTRP2 5.3858 8.3638 3.66 5.1927
MG-63 GDSC1; GDSC2; CTRP2 5.4489 11.3049 2.2446 10.9563
CHSA0011 GDSC1; GDSC2 6.1975 17.1711 -1.3772 18.6674
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 6.7192 12.0567 2.8167 6.5651
CAL-78 GDSC1; GDSC2 6.981 18.001 -1.2376 16.5815
HOS GDSC1; GDSC2; CTRP2 11.0828 23.837 0.0765 10.6858
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 218 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -0.7991 3.2687 -0.9504 39.3578
MEC1 CTRP2 2.982 6.2829 2.3661 15.9985
JM1 GDSC1; GDSC2; CTRP2 2.7992 5.2385 2.5385 15.877
MHH-CALL-3 CTRP2 -1.8584 28.4807 -12.8277 48.9357
MHH-CALL-4 GDSC2; CTRP2 -1.3697 1.8275 -1.4047 42.8226
Kasumi-2 CTRP2 -0.7994 1.9654 -0.8233 39.0065
ALL-PO GDSC1; GDSC2 -0.3964 5.769 -1.5925 41.0637
EoL-1 GDSC1; GDSC2; CTRP2 -0.3418 2.4488 -0.3778 36.0001
Hs 611.T CTRP2 -0.1948 2.763 -0.2486 35.0791
MOLT-16 GDSC1; GDSC2; CTRP2 -0.1457 1.2208 -0.146 34.578
Ki-JK CTRP2 -0.0908 3.2158 -0.1869 34.5226
SIG-M5 GDSC2; CTRP2 0.0249 3.0457 -0.0447 33.6691
KMS-28BM CTRP2 0.0844 3.5858 -0.0514 33.4868
NKM-1 GDSC1; GDSC2 0.249 4.3414 -0.3564 33.6643
MOLM-13 GDSC1; GDSC2; CTRP2 0.2899 2.2148 0.2823 31.7005
MV4-11 GDSC1; GDSC2 0.5268 2.2694 0.4813 28.2801
KMS-21-BM CTRP2 0.649 2.4517 0.6413 29.3081
OCI-Ly3 CTRP2 0.6716 1.4537 0.6716 29.1319
NALM-6 GDSC1; GDSC2; CTRP2 0.6931 13.3951 -3.1444 38.1987
Mino CTRP2 0.7514 3.7143 0.644 28.9624
HuNS1 CTRP2 0.7611 2.7189 0.7466 28.5843
Karpas-231 GDSC1; GDSC2 0.8044 2.503 0.747 25.5563
SUP-T11 CTRP2 0.8365 2.7996 0.8206 28.0868
JVM-3 GDSC1; GDSC2; CTRP2 0.9361 3.6178 0.8547 27.6447
SUP-B15 GDSC1; GDSC2; CTRP2 1.0117 3.9163 0.8921 27.2715
BV-173 GDSC1; GDSC2 1.1327 4.3844 0.5771 24.9395
Mono-Mac-1 CTRP2 1.1725 4.2503 1.0061 26.3626
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 1.1891 3.0544 1.1715 25.8152
KE-97 CTRP2; CTRP1 1.1901 3.9057 1.0865 26.1006
KMS-27 CTRP2 1.2734 3.5261 1.2229 25.2932
BONNA-12 GDSC2 1.283 4.1819 0.8144 22.9871
MOLT-3 CTRP2 1.4112 1.9329 1.4112 24.2051
SUP-B8 GDSC1; GDSC2 1.5966 4.3391 1.0888 20.1023
CML-T1 GDSC1; GDSC2; CTRP2 1.6083 2.5765 1.6079 22.8931
JVM-2 GDSC1; GDSC2 1.6548 5.8581 0.4918 23.1897
NCO2 CTRP2 1.6744 4.0092 1.5888 22.7423
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 1.722 3.6258 1.6859 22.3309
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 1.745 5.3957 1.3419 23.3952
CCRF-CEM GDSC1; GDSC2 1.7744 6.1044 0.4971 22.6849
Granta-519 GDSC1; GDSC2; CTRP2 1.8148 3.5701 1.7873 21.6084
Ri-1 CTRP2 1.8286 4.725 1.6167 22.1571
JURL-MK1 GDSC1; GDSC2; CTRP2 1.8567 4.1368 1.7647 21.5502
CTV-1 GDSC1; GDSC2 1.8976 4.011 1.537 16.2699
Pfeiffer CTRP2 1.9203 4.3834 1.7901 21.2593
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 1.9273 3.6023 1.9027 20.9253
RS4;11 GDSC1; GDSC2; CTRP2 1.934 3.9164 1.8784 20.91
697 GDSC1; GDSC2; CTRP2 1.9493 3.7564 1.912 20.7457
Kasumi-1 GDSC1; GDSC2; CTRP2 2.0018 3.5884 1.9807 20.3411
EHEB GDSC1; CTRP2 2.0379 6.6824 1.2059 23.0238
A4/Fukuda GDSC1; GDSC2; CTRP2 2.0426 4.3922 1.9207 20.4161
PL21 CTRP1 2.0536 3.9183 2.0058 43.1704
BL-70 CTRP2; CTRP1 2.0711 4.2986 1.9699 20.231
RPMI-8866 GDSC1; GDSC2 2.0778 5.8298 0.9241 19.1299
SUP-HD1 GDSC1; GDSC2; CTRP2 2.0806 4.1359 2.0051 20.0018
MM1.S GDSC1; GDSC2; CTRP2 2.095 4.1104 2.0242 19.8898
GR-ST GDSC1; GDSC2 2.1004 7.7013 0.0463 23.772
ATN-1 GDSC1; GDSC2 2.1017 3.8772 1.8061 13.8631
DoHH2 GDSC2 2.1607 3.4393 2.0208 12.3972
CRO-AP2 GDSC1; GDSC2 2.1673 4.2006 1.7473 13.9306
Peer CTRP2 2.1705 3.9322 2.1272 19.2927
SU-DHL-5 GDSC1; GDSC2; CTRP1 2.2304 4.3293 2.1363 24.5819
SKM-1 GDSC1; GDSC2; CTRP1 2.248 6.6721 1.4382 27.6197
RPMI-6666 GDSC1; GDSC2; CTRP2 2.2572 4.4278 2.1461 18.9491
KMS-34 CTRP2 2.2614 4.5306 2.1304 18.9908
GDM-1 GDSC1; GDSC2; CTRP1 2.2763 3.625 2.2633 23.8347
BALL-1 GDSC1; GDSC2 2.2941 5.897 1.1022 17.2877
SU-DHL-1 GDSC2; CTRP2 2.3359 4.6516 2.1858 18.5622
A3/Kawakami GDSC1; GDSC2; CTRP2 2.346 4.2939 2.2653 18.2522
OCI-Ly19 GDSC1; GDSC2; CTRP2 2.3796 4.2766 2.3042 18.0098
MOLP-8 GDSC1; GDSC2; CTRP2 2.4022 5.1456 2.1326 18.5487
EB1 CTRP2 2.4251 6.1008 1.841 19.558
WSU-NHL GDSC1 2.4348 3.4264 2.3233 11.8286
SU-DHL-6 GDSC1; GDSC2; CTRP2 2.4936 4.0708 2.4537 17.1285
KMS-11 GDSC1; GDSC2; CTRP1 2.5008 4.1686 2.4503 22.0794
KE-37 GDSC1; GDSC2; CTRP2 2.5037 4.5655 2.3862 17.33
KMS-20 CTRP2 2.5044 5.0418 2.2731 17.7307
JSC-1 GDSC1; GDSC2 2.5291 6.566 0.9996 17.0584
HC-1 GDSC1; GDSC2 2.5401 4.5064 1.9969 10.9781
NOMO-1 GDSC1; GDSC2; CTRP1 2.5502 4.0237 2.519 21.5729
GA-10 GDSC1; GDSC2; CTRP2 2.5696 4.8771 2.3874 17.1206
BC-3 GDSC2 2.5731 4.8202 1.884 11.5425
OCI-Ly7 GDSC1; GDSC2 2.5747 3.5126 2.4474 8.1847
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 2.601 4.1123 2.5634 16.4857
MOTN-1 CTRP2 2.6303 4.7967 2.4731 16.6275
NB4 GDSC1; GDSC2 2.6429 4.3675 2.1635 9.5811
Ku812 GDSC1; GDSC2; CTRP2; CTRP1 2.6557 4.5177 2.5617 16.3163
SEM CTRP2 2.6574 4.7204 2.5202 16.3764
HAL-01 GDSC1; GDSC2 2.6709 4.8707 1.9552 10.7519
Daudi GDSC1; GDSC2; CTRP2 2.6736 3.8201 2.6627 15.831
SUP-M2 GDSC1; GDSC2; CTRP2 2.682 3.583 2.6794 15.7472
RPMI-8402 GDSC1; GDSC2; CTRP2 2.6989 4.0518 2.6722 15.7157
MHH-PREB-1 GDSC1; GDSC2 2.7 4.2159 2.2899 8.6
MLMA GDSC1; GDSC2 2.7133 6.9353 0.986 16.5126
MOLM-6 CTRP2 2.7424 4.3775 2.6778 15.5563
BC-1 GDSC1; GDSC2 2.7462 4.3937 2.254 8.6454
SET-2 CTRP2 2.7753 6.3082 2.1366 17.4506
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 2.7986 4.8686 2.6392 15.515
DB GDSC1; GDSC2; CTRP2 2.8163 6.0364 2.2847 16.7728
RCH-ACV GDSC1; GDSC2; CTRP2 2.8814 4.4627 2.8135 14.6417
QIMR-WIL GDSC1; GDSC2 2.883 6.0173 1.593 12.2756
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 2.9107 4.5358 2.8338 14.5603
U-698-M GDSC1; GDSC2 2.9207 5.1779 2.0415 9.3534
Karpas-1106P GDSC1; GDSC2 2.9209 5.0599 2.0997 8.9888
HPB-ALL CTRP2 2.923 5.59 2.5602 15.4315
KMS-12-BM GDSC1; GDSC2; CTRP2 2.9261 4.493 2.8565 14.3501
Farage GDSC1; GDSC2 2.9416 5.2389 2.0306 9.3524
HDLM-2 GDSC1; GDSC2; CTRP2 2.9774 5.4493 2.6664 14.8779
L-363 GDSC1; GDSC2; CTRP2 2.9829 6.3052 2.3581 16.0267
CTB-1 GDSC1; GDSC2 3.0389 5.3861 2.0454 8.9434
LAMA-84 GDSC1; GDSC2; CTRP2 3.0619 4.9321 2.9105 13.7344
KCL-22 GDSC1; GDSC2; CTRP2 3.1058 6.0452 2.5908 14.7943
L-540 GDSC1; GDSC2; CTRP2 3.1147 5.0016 2.95 13.4306
KOPN-8 GDSC2 3.1604 7.8501 0.9219 15.4565
OCI-AML-2 GDSC1; GDSC2 3.1607 4.4978 2.5948 5.095
DND-41 GDSC1; GDSC2 3.1825 5.5461 2.0917 8.2032
MOLP-2 CTRP2 3.1976 5.0381 3.0306 12.8875
P32/ISH GDSC1; GDSC2 3.2001 5.1187 2.3201 6.7066
MEG-01 GDSC1; GDSC2 3.2279 5.3538 2.2266 7.213
KM-H2 GDSC1; GDSC2; CTRP2 3.2399 4.951 3.0998 12.5093
DG-75 GDSC1; GDSC2 3.2499 6.4892 1.6779 10.6026
NU-DHL-1 CTRP2 3.2509 4.5519 3.1962 12.1349
Mono-Mac-6 GDSC1; GDSC2; CTRP2 3.2539 8.1099 1.8476 17.309
TK [Human B-cell lymphoma] GDSC1; GDSC2 3.2617 4.5654 2.6493 4.4369
OCI-AML-5 GDSC1; GDSC2; CTRP2 3.2785 4.9168 3.1505 12.2095
HEL 92.1.7 CTRP2 3.2875 6.1213 2.7541 13.6634
Hs 445 GDSC2 3.3059 6.5082 1.7155 10.202
EM-2 GDSC1; GDSC2; CTRP2 3.3061 5.3046 3.0704 12.4165
Sc-1 GDSC1 3.3148 4.3061 2.8239 3.954
BL-41 GDSC1; GDSC2 3.3252 4.9103 2.5305 5.0013
VAL GDSC1; GDSC2 3.3344 5.1453 2.4206 5.6704
K-562 GDSC1; GDSC2; CTRP2 3.3461 6.2344 2.7705 13.4395
MC116 GDSC1; GDSC2; CTRP2; CTRP1 3.3593 4.3679 3.3372 11.3861
BE-13 GDSC1; GDSC2 3.3645 6.6349 1.7007 10.1235
Ramos.2G6.4C10 GDSC1; GDSC2 3.3678 5.0151 2.5132 4.9884
ALL-SIL GDSC1; GDSC2 3.3802 5.6974 2.1824 7.0466
ML-2 GDSC1; GDSC2 3.3895 6.0132 2.0322 7.9688
TUR GDSC1; GDSC2 3.3958 5.1604 2.4635 5.224
IM-9 GDSC1; GDSC2 3.4001 5.0789 2.5078 4.932
MY-M12 GDSC1; GDSC2 3.4035 5.2046 2.4477 5.3027
SU-DHL-10 GDSC1; GDSC2; CTRP2 3.4055 4.7434 3.3281 11.1845
Loucy GDSC1; GDSC2 3.4056 6.677 1.7136 9.9251
EB2 GDSC1; GDSC2 3.4233 4.7198 2.7056 3.6176
Karpas-620 GDSC1; GDSC2 3.4364 4.8295 2.6613 3.8618
PF-382 GDSC1; GDSC2; CTRP2 3.4489 5.1366 3.2771 11.2336
KY821 GDSC1; GDSC2 3.4579 4.6977 2.7438 3.2837
KMS-18 CTRP2 3.4629 7.6239 2.2799 15.0722
KHM-1B CTRP2 3.4746 4.7764 3.3962 10.728
Namalwa GDSC1; GDSC2; CTRP2 3.5125 4.7217 3.4484 10.4255
WIL2 NS GDSC1; GDSC2 3.5195 5.6167 2.3348 5.6988
M-07e CTRP2 3.5238 4.7786 3.4492 10.3873
MOLT-13 GDSC1; GDSC2 3.5255 6.2203 2.0387 7.5485
ST486 GDSC1; CTRP2 3.5269 5.0424 3.3888 10.5928
VL51 GDSC1; GDSC2 3.5405 7.206 1.5589 10.5054
NCI-H929 GDSC1; GDSC2; CTRP2 3.5626 5.2507 3.3665 10.5667
Toledo CTRP2 3.5632 9.9082 1.2897 18.718
KMS-26 CTRP2 3.573 4.4734 3.551 9.8769
LC4-1 GDSC1; GDSC2 3.5859 5.5378 2.4255 4.9528
AML-193 CTRP2 3.5958 4.4439 3.5781 9.7104
MOLT-4 GDSC1; GDSC2 3.6037 5.856 2.2814 5.8127
Reh GDSC1; GDSC2 3.6067 6.9865 1.7213 9.3167
CA46 GDSC1; GDSC2; CTRP2 3.6127 5.0982 3.4669 10.0498
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 3.6216 5.1566 3.4626 10.1254
JJN-3 GDSC1; GDSC2; CTRP2 3.6242 6.0231 3.1494 11.2137
Raji GDSC1; GDSC2 3.6247 4.8653 2.7857 2.6092
JeKo-1 GDSC1; GDSC2; CTRP2 3.643 6.0804 3.1459 11.1762
P30/OHK GDSC1; GDSC2 3.646 5.5889 2.4459 4.673
PL-21 GDSC1; GDSC2 3.679 6.1676 2.1846 6.2261
F-36P CTRP2 3.6802 6.7649 2.8891 12.0895
ARH-77 GDSC1; GDSC2 3.6906 5.5055 2.5201 4.1005
KYO-1 CTRP2 3.7249 4.8913 3.6432 9.0732
KMOE-2 GDSC1; GDSC2 3.7322 6.6983 1.9623 7.481
SU-DHL-16 GDSC1; GDSC2 3.7386 5.8916 2.3656 4.9456
Karpas-45 GDSC1; GDSC2 3.7431 5.6561 2.4845 4.1957
SU-DHL-8 GDSC1; GDSC2; CTRP2 3.7583 4.7018 3.7173 8.7079
TF-1 CTRP2 3.7735 6.8625 2.9395 11.6507
HEL GDSC1; GDSC2; CTRP2 3.8247 5.6212 3.5209 9.2313
CESS GDSC1; GDSC2 3.8351 6.6811 2.0485 6.6841
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 3.8408 5.7568 3.4903 9.39
Jiyoye GDSC1; GDSC2 3.8486 5.4392 2.6635 2.8632
CMK GDSC1; CTRP2 3.8559 6.3044 3.2723 10.1136
SUP-T1 GDSC1; GDSC2 3.8562 5.6677 2.5589 3.4808
L-1236 GDSC1; GDSC2; CTRP2 3.8614 6.0148 3.4019 9.5895
P3HR-1 CTRP2; CTRP1 3.926 6.1398 3.4216 9.4266
P12-Ichikawa GDSC1; CTRP2 3.9462 5.3173 3.7617 7.9761
Jurkat GDSC1; GDSC2; CTRP2 4.0455 5.1391 3.927 7.0727
SK-MM-2 GDSC1; GDSC2; CTRP2 4.0737 6.0211 3.6197 8.1707
P31/FUJ GDSC1; GDSC2; CTRP2 4.0791 5.5155 3.8331 7.327
HL-60 GDSC1; GDSC2; CTRP2 4.1041 5.7932 3.7483 7.5853
YT GDSC1; GDSC2 4.1469 6.2967 2.4531 3.5139
U266B1 GDSC2; CTRP2 4.1514 6.2009 3.6199 7.9684
SCC-3 GDSC2 4.1558 7.285 1.985 6.3189
HT GDSC1; GDSC2; CTRP2; CTRP1 4.159 5.0583 4.077 6.2758
MHH-CALL-2 GDSC1 4.1611 6.2496 2.4844 4.1118
MN-60 GDSC1; GDSC2 4.1677 5.8094 2.6923 2.0955
KO52 CTRP2 4.1719 5.0657 4.0863 6.1127
OPM-2 GDSC1; GDSC2; CTRP2 4.2002 6.3159 3.6171 7.856
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 4.2127 6.8821 3.3726 8.9016
EJM GDSC1; GDSC2; CTRP2; CTRP1 4.2329 6.1275 3.7418 7.3613
U-937 CTRP2; CTRP1 4.237 5.7962 3.8911 6.7602
Karpas-422 GDSC1; GDSC2; CTRP2 4.2457 5.834 3.8783 6.6988
Karpas-299 GDSC1; GDSC2 4.2673 7.3848 2.0142 5.8949
OCI-M1 GDSC1; GDSC2; CTRP2 4.3009 6.95 3.4182 8.4203
L-428 GDSC1; GDSC2; CTRP2 4.3356 5.7115 4.024 5.888
RPMI-8226 GDSC1; GDSC2; CTRP1 4.3522 5.5832 4.1007 7.2331
OCI-Ly10 CTRP2; CTRP1 4.4028 6.7941 3.5982 7.5282
HuT 78 CTRP2 4.4601 6.1033 3.9739 5.7709
ROS-50 GDSC1; GDSC2 4.5208 7.0345 2.3441 3.4502
NK-92MI GDSC2 4.5303 6.2208 2.7126 1.4583
H9 GDSC1; GDSC2 4.554 7.957 1.9333 5.778
RC-K8 GDSC1 4.6048 6.5059 2.6292 2.2125
DEL GDSC1; GDSC2; CTRP2 4.6077 5.2638 4.494 3.3237
SR GDSC1; GDSC2; CTRP2 4.6123 8.668 2.861 10.0424
ME1 GDSC1; GDSC2 4.6127 5.7973 2.9242 0.4725
KMM-1 CTRP2 4.8982 11.9048 1.4916 15.0182
RL GDSC1; GDSC2; CTRP2 5.0477 9.7901 2.6743 9.9424
KG-1 GDSC1; GDSC2 5.3121 7.3586 2.623 1.0427
REC-1 CTRP2 6.4585 8.7385 4.2002 1.5755
HD-MY-Z CTRP2 7.8767 17.4279 1.0246 11.6753
⏷ Show the Full List of 218 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 4.7021 6.35 4.0882 4.7327
TE8 CTRP2 5.0598 7.16 3.9994 4.3629
OE21 GDSC1; GDSC2; CTRP2 2.8658 6.5845 2.1218 17.2567
T.T GDSC1; GDSC2 3.4758 5.6149 2.301 6.0299
KYSE-520 GDSC1; GDSC2; CTRP2 3.6052 7.1688 2.6309 13.3114
KYSE-270 GDSC1; GDSC2 3.6754 6.9931 1.772 8.8167
TE-8 GDSC1; GDSC2 3.7586 8.4439 1.1152 12.5909
KYSE-410 GDSC1; GDSC2; CTRP1 3.9097 5.9047 3.5036 11.748
TE-5 GDSC1; GDSC2; CTRP2 4.0625 8.0651 2.654 12.1133
KYSE-70 GDSC1; GDSC2; CTRP2 4.1468 6.3949 3.5275 8.3504
TE-9 GDSC1; GDSC2; CTRP2 4.1713 8.4977 2.5453 12.311
TE-11 GDSC1; GDSC2; CTRP2 4.1837 7.8489 2.8732 10.9333
EC-GI-10 GDSC1; GDSC2; CTRP2 4.2825 8.1517 2.8176 10.9388
TE-4 GDSC1; GDSC2; CTRP2 4.3288 6.4933 3.6623 7.3562
TE-6 GDSC1; GDSC2; CTRP2 4.4096 6.8854 3.5531 7.6118
TE-14 CTRP2 4.531 5.8217 4.1745 4.7851
KYSE-140 GDSC1; GDSC2; CTRP2; CTRP1 4.6148 9.1163 2.6492 10.9984
TE-15 GDSC1; GDSC2 4.7378 8.1564 1.9582 5.2713
COLO 680N GDSC1; GDSC2; CTRP2 4.9355 6.8328 4.058 4.3613
KYSE-30 CTRP2 4.9801 6.5781 4.2233 3.5776
TE-10 GDSC1; GDSC2; CTRP2 5.016 10.3066 1.1207 7.2486
OE19 GDSC1; GDSC2; CTRP2 5.017 7.7957 3.6459 5.9316
OE33 GDSC1; GDSC2; CTRP2 5.0819 9.1228 3.0363 8.3651
KYSE-450 GDSC1; GDSC2; CTRP2; CTRP1 5.1482 7.0965 4.1135 3.8009
TE-1 GDSC1; GDSC2; CTRP2 5.3193 8.2078 3.6856 5.2026
KYSE-180 GDSC1; GDSC2; CTRP2 5.4614 7.6654 4.0631 3.3862
KYSE-150 GDSC1; GDSC2; CTRP2 6.3854 8.6897 4.1808 1.7161
KYSE-510 GDSC1; GDSC2; CTRP2 7.2907 12.8422 2.8209 5.7776
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.3044 7.9922 1.9522 16.7702
HPAC GDSC1; GDSC2; CTRP2 3.1403 4.808 3.0259 13.0807
PaTu 8988s CTRP2 3.3688 6.3108 2.7629 13.4072
PaTu 8988t GDSC1; GDSC2; CTRP2 3.4146 5.4669 3.1347 11.86
SUIT-2 GDSC1; GDSC2; CTRP2; CTRP1 3.7089 7.6709 2.5084 13.6272
MIA PaCa-2 GDSC1; GDSC2; CTRP2 3.7569 6.1424 3.2393 10.5053
Panc 10.05 GDSC1; GDSC2; CTRP2 3.8462 5.5921 3.555 9.0409
HuP-T4 GDSC1; GDSC2; CTRP2; CTRP1 3.9187 4.9176 3.8501 7.8257
BxPC-3 GDSC1; GDSC2; CTRP2 3.944 6.9285 3.0796 10.6604
PaTu 8902 GDSC1; GDSC2; CTRP2; CTRP1 3.9945 6.3097 3.418 9.2619
PL4 GDSC1; GDSC2 4.0259 6.844 2.1075 5.8649
Panc 04.03 GDSC1; GDSC2; CTRP2 4.0327 10.7363 1.3169 17.5311
Capan-2 GDSC1; CTRP2; CTRP1 4.1074 6.9593 3.2334 9.7218
Panc 05.04 CTRP2 4.2079 10.001 1.8386 15.1008
KP-3 GDSC1; GDSC2; CTRP2; CTRP1 4.2291 6.1764 3.7161 7.4737
SNU-213 CTRP2 4.2511 6.0746 3.7778 7.0836
Panc 08.13 GDSC1; GDSC2; CTRP2 4.2555 5.4441 4.0489 6.0093
Panc 03.27 GDSC1; GDSC2; CTRP2; CTRP1 4.2598 6.9038 3.4081 8.6442
KP-1N GDSC1; GDSC2 4.2623 6.7746 2.3023 4.1781
Hs 766T GDSC1; GDSC2; CTRP2 4.2732 6.4449 3.6302 7.6219
MZ-PC-1 GDSC1; GDSC2 4.2915 9.9225 0.7907 13.0603
YAPC GDSC1; GDSC2; CTRP2 4.4599 8.5458 2.7855 10.6814
PK-59 CTRP2 4.5665 9.9874 2.1642 13.0163
DAN-G GDSC1; GDSC2; CTRP2 4.5808 9.3851 2.4766 11.7039
SW1990 GDSC1; GDSC2; CTRP2 4.6377 7.666 3.3809 7.8186
Panc 02.03 GDSC1; GDSC2; CTRP2 4.734 7.7564 3.4217 8.6115
TCC-Pan2 CTRP2 4.7518 7.2934 3.6676 6.3776
HuP-T3 GDSC1; GDSC2; CTRP2 4.8029 6.2467 4.2318 3.9121
SNU-410 CTRP2 4.8434 7.3391 3.7256 5.944
SU.86.86 GDSC1; GDSC2; CTRP2 4.901 7.4037 3.7432 5.7528
Capan-1 GDSC1; GDSC2; CTRP2 4.9106 7.4464 3.7302 5.7878
CFPAC-1 GDSC1; GDSC2; CTRP2 4.912 7.7803 3.5646 6.4804
KP-2 GDSC1; GDSC2; CTRP2 5.0423 6.1633 4.4832 2.3631
PSN1 GDSC1; GDSC2; CTRP2 5.0795 7.8944 3.6485 5.7999
QGP-1 GDSC1; GDSC2; CTRP2; CTRP1 5.0877 7.0868 4.0688 4.1022
AsPC-1 GDSC1; GDSC2; CTRP2 5.3184 9.718 2.9319 8.3584
PK-45H CTRP2 5.3976 8.2467 3.7273 4.8909
L3.3 CTRP2 5.4088 7.9235 3.8961 4.1673
KP-4 GDSC1; GDSC2; CTRP2 5.4781 7.3435 4.2332 2.6585
HPAF-II GDSC1; CTRP2 6.4071 16.3959 0.4604 15.9778
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 4.2445 8.492 2.6158 13.6988
Hs 852.T CTRP2; CTRP1 1.6235 4.3301 1.4807 23.3533
G-mel GDSC1; GDSC2 1.6459 8.0264 -0.5402 28.1735
Malme-3M CTRP2 2.65 8.3506 1.1326 21.6023
MZ-MEL-7 GDSC1; GDSC2 2.673 4.9393 1.9245 10.9332
Mel Ho GDSC1; GDSC2; CTRP2 2.7122 3.882 2.699 15.5816
G-361 GDSC1; GDSC2; CTRP2; CTRP1 2.7802 4.2778 2.7336 15.324
SK-MEL-3 GDSC1; GDSC2; CTRP2 2.8762 4.8097 2.7379 14.9236
SK-MEL-24 GDSC1; GDSC2; CTRP2 2.9716 5.0005 2.7942 14.4285
Hs 940.T GDSC1; GDSC2; CTRP2 3.0019 5.9648 2.5104 15.3922
HMV-II GDSC1; GDSC2 3.0338 4.4034 2.5256 5.9471
SH-4 GDSC1; GDSC2 3.0792 4.9259 2.3096 7.1519
RPMI-7951 GDSC1; GDSC2 3.1968 6.7162 1.5195 11.7467
CP50-MEL-B GDSC1; GDSC2 3.2871 6.3487 1.7794 9.857
A-375 GDSC1; GDSC2; CTRP2; CTRP1 3.3018 5.0874 3.1334 12.2839
WM793 GDSC1; GDSC2; CTRP2 3.346 7.1694 2.3686 15.0166
A-431 GDSC1; GDSC2 3.3967 5.7908 2.1492 7.2095
GAK GDSC1; GDSC2 3.4204 5.6043 2.2617 6.4315
COLO 792 GDSC1; GDSC2; CTRP2 3.428 5.8821 2.9974 12.3405
Hs 938.T GDSC1; GDSC2 3.4739 5.7602 2.2271 6.502
WT2-iPS GDSC1; GDSC2; CTRP2 3.567 6.1574 3.0343 11.8159
IST-MEL1 GDSC1; GDSC2 3.6067 6.8532 1.7877 8.9029
COLO 783 GDSC2 3.6183 6.745 1.8507 8.4776
MZ-MEL-2 GDSC1; GDSC2 3.6211 5.6303 2.4066 4.9815
Hs 936.T CTRP2; CTRP1 3.6446 5.1809 3.4805 9.991
M14 GDSC1 3.6461 5.6509 2.4154 6.057
UACC-257 GDSC1; GDSC2; CTRP2 3.6605 10.4821 1.1008 19.2009
COLO 800 GDSC1; GDSC2; CTRP2 3.703 8.7092 2.0017 15.6001
WM278 GDSC1; GDSC2 3.7313 7.0244 1.7998 8.496
A-388 GDSC1; GDSC2 3.7562 8.5511 1.0598 12.9229
LOX-IMVI GDSC1; GDSC2; CTRP2 3.8057 6.106 3.3054 10.1162
A2058 GDSC1; GDSC2; CTRP2 3.8112 6.5829 3.1036 10.899
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 3.8196 4.6239 3.7957 8.3291
WM115 GDSC1; GDSC2; CTRP2 3.8359 7.7619 2.5823 12.9399
Mel JuSo GDSC1; GDSC2 3.8939 7.1243 1.8739 7.6223
IGR-37 GDSC1; GDSC2; CTRP2 3.9648 4.9889 3.8808 7.4848
HT-144 GDSC1; GDSC2; CTRP2 4.0016 9.3257 1.9828 14.9835
COLO 679 GDSC1; GDSC2 4.1388 10.985 0.1481 16.875
MeWo GDSC1; GDSC2; CTRP2 4.2144 6.4548 3.5674 8.0211
Hs 934.T CTRP2 4.2181 5.2491 4.0794 6.001
SK-MEL-30 GDSC1; GDSC2; CTRP2 4.2763 5.2972 4.1257 5.6593
VMRC-MELG GDSC1; GDSC2 4.3198 7.5005 1.9944 5.9014
LB373-MEL-D GDSC1; GDSC2 4.3373 6.4112 2.519 2.7797
WM1799 CTRP2 4.3422 6.8551 3.5033 7.9737
DJM-1 GDSC1; GDSC2 4.3566 8.9275 1.3277 9.8126
IGR-1 GDSC1; GDSC2; CTRP2 4.3764 5.7318 4.0575 5.6484
CP66-MEL GDSC1; GDSC2 4.4196 8.1222 1.7635 7.0716
WM1552C GDSC1; GDSC2 4.471 8.6482 1.545 8.2612
RVH-421 GDSC1; GDSC2; CTRP2 4.4751 7.9953 3.0713 9.4609
K029AX CTRP2 4.4853 4.964 4.4542 3.8322
IGR-39 CTRP2 4.4918 10.7655 1.7113 14.9947
451Lu GDSC1; GDSC2 4.4989 11.1021 0.3639 14.8418
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 4.576 5.9567 4.1637 4.8071
Hs 895.T CTRP2 4.6009 5.2342 4.4979 3.3283
Hs 688(A).T CTRP2 4.6699 6.0755 4.1911 4.3813
WM88 CTRP2 4.6847 11.2133 1.6552 14.8132
WM266-4 CTRP2 4.7644 5.4821 4.5637 2.635
CJM [Human melanoma] CTRP2 4.7718 5.3736 4.6202 2.3903
Hs 944.T CTRP2; CTRP1 4.8272 6.9858 3.8961 5.3488
IPC-298 GDSC1; GDSC2; CTRP2 4.8848 6.4685 4.1953 3.8893
WM983B CTRP2 4.8855 5.8842 4.4857 2.6743
COLO 741 CTRP2 5.0436 6.7686 4.1817 3.6279
MMAc-SF GDSC1; GDSC2 5.1251 11.6072 0.5688 12.2914
HMCB CTRP2 5.1599 6.277 4.5215 1.9846
CHL-1 GDSC1; GDSC2 5.1907 11.2004 0.8103 10.8593
MDA-MB-435S CTRP2 5.217 7.0192 4.1969 3.243
COLO 829 GDSC1; GDSC2; CTRP2 5.2762 11.8882 1.8137 13.0127
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 5.6139 6.7288 4.6286 0.9754
Hs 839.T CTRP2 5.71 10.7644 2.7184 8.5485
LB2518-MEL GDSC1; GDSC2 6 14.9295 -0.43 15.228
Hs 294T CTRP2 6.0289 10.5599 3.0579 6.6252
SK-MEL-2 GDSC1; GDSC2; CTRP2 6.0637 7.3611 4.5848 0.6442
WM35 GDSC1; GDSC2 6.4004 19.8252 -2.526 22.1247
A101D GDSC1; GDSC2; CTRP2 6.4595 11.9946 2.6664 7.5477
SK-MEL-31 GDSC1; GDSC2; CTRP2 6.7107 13.9579 1.8885 10.2346
UACC-62 GDSC1; GDSC2; CTRP2 6.9611 14.8672 1.6243 10.8555
EquiPSC Line K2 GDSC1; GDSC2 4.2464 7.2971 2.042 5.772
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC1; GDSC2 2.1487 5.895 0.9626 18.6414
KYSE-220 GDSC1; GDSC2 2.3612 5.7423 1.2407 16.2203
KYSE-50 GDSC1; GDSC2 3.2829 4.9936 2.4534 5.6139
OACP4 C GDSC1; GDSC2 3.3465 6.8971 1.5548 11.0839
SK-GT-4 GDSC1; GDSC2 3.4783 6.1154 2.0533 7.5868
ESO-51 GDSC1; GDSC2 3.7935 6.9788 1.8701 7.8985
FLO-1 GDSC1; GDSC2 3.991 7.947 1.5406 9.4273
TE-12 GDSC1; GDSC2 4.6177 9.0009 1.4763 8.3415
OACM5.1 C GDSC1; GDSC2 4.6754 6.9354 2.4795 2.4525
ESO-26 GDSC1; GDSC2 5.0926 7.7147 2.3666 2.4469
KYAE-1 GDSC1; GDSC2 6.1843 15.1057 -0.389 14.6669
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 3.775 5.7385 2.4673 4.2275
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 GDSC2; CTRP2 0.9589 2.708 0.9496 27.2493
NH-6 CTRP2 1.3949 5.1169 1.0415 25.5383
SK-N-BE(2) CTRP2 1.5987 5.6163 1.1136 24.6564
SK-N-MC-IXC GDSC1; GDSC2 1.6506 3.1846 1.5336 17.3834
Kelly GDSC1; GDSC2; CTRP2 1.9916 4.3659 1.8705 20.7528
NB69 GDSC1; GDSC2 2.1635 5.6641 1.086 17.8651
SK-N-DZ GDSC1; GDSC2 2.3373 5.4256 1.3682 15.5417
CHP-126 GDSC1; GDSC2; CTRP2 2.446 4.0255 2.4083 17.4384
GI-ME-N GDSC1; GDSC2 2.6283 5.0901 1.8094 11.8009
SJNB-14 GDSC1; GDSC2 2.9841 7.6855 0.8526 16.4081
IMR-32 CTRP2 2.9868 5.3295 2.715 14.6709
KP-N-YS GDSC2 3.0594 4.9427 2.2836 7.3793
SK-N-SH GDSC1; GDSC2; CTRP2 3.2625 7.7336 2.0292 16.5721
GOTO GDSC1; GDSC2 3.3553 6.206 1.9077 8.8519
NB1 GDSC1; GDSC2; CTRP2 3.3757 5.9666 2.9088 12.8251
LA-N-6 GDSC1; GDSC2 3.4101 8.5681 0.772 15.5673
SiMa GDSC1; GDSC2 3.4808 5.4756 2.3745 5.5521
SJNB-17 GDSC1; GDSC2 3.5675 6.1863 2.0889 7.1193
KP-N-RT-BM-1 GDSC2 3.6397 5.6676 2.4022 4.9619
NH-12 GDSC1; GDSC2 3.7282 8.0656 1.2796 11.6937
SJNB-10 GDSC1; GDSC2 3.822 7.3453 1.7103 8.8156
SJNB-5 GDSC1; GDSC2 4.0037 6.2012 2.4032 4.1076
SK-N-BE(2)-M17 GDSC1; GDSC2 4.0209 7.0292 2.0136 6.4537
TGW GDSC1; GDSC2 4.2341 7.7121 1.8328 7.0673
SJNB-7 GDSC1; GDSC2 4.2541 6.7575 2.3051 4.1781
CHP-212 GDSC1; GDSC2; CTRP2 4.2802 7.9126 2.9324 10.4696
SJNB-13 GDSC1; GDSC2 4.36 7.0715 2.2256 4.438
SK-N-FI GDSC1; GDSC2 4.4386 8.0957 1.7894 6.8758
KP-N-YN GDSC1; GDSC2; CTRP2 4.4613 8.2273 2.9442 10.019
SJNB-12 GDSC1; GDSC2 4.4929 10.4401 0.6853 13.142
IMR-5 GDSC1; GDSC2 4.674 7.0522 2.4267 2.7381
NB(TU)1 GDSC1; GDSC2 4.7914 12.5434 -0.1289 16.5713
SJNB-6 GDSC1; GDSC2 4.9174 6.895 2.6247 1.4171
SK-N-AS GDSC1; GDSC2; CTRP2 6.2636 12.5749 2.2406 9.5635
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 2.5318 5.4078 2.1951 17.9322
SNU-869 CTRP2 4.2468 9.7864 1.9799 14.4485
SNU-478 CTRP2 4.3223 5.5223 4.089 5.6702
HuCC-T1 GDSC1; GDSC2; CTRP2 4.5315 7.3477 3.4416 7.797
HuH-28 CTRP2 4.6264 5.7633 4.2965 4.0559
SNU-1196 CTRP2 5.0555 6.7878 4.1819 3.6041
SNU-308 CTRP2 5.2859 6.6727 4.4217 2.1865
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-148 GDSC2; CTRP2 -0.9051 2.0942 -0.9396 39.7401
MDA-MB-157 GDSC1; GDSC2; CTRP2 2.3511 5.8734 1.8433 19.7631
AU565 GDSC1; GDSC2; CTRP2 2.4007 6.1721 1.7884 19.8247
CAL-51 GDSC1; GDSC2; CTRP2 2.8701 4.1166 2.8461 14.5661
HCC1806 GDSC1; GDSC2; CTRP2 2.9096 5.3259 2.6321 15.205
DU4475 GDSC1; GDSC2; CTRP2 3.033 5.1836 2.8097 14.1864
HCC1569 GDSC1; GDSC2 3.1452 8.0716 0.7983 16.2157
MDA-MB-231 GDSC1; GDSC2 3.2393 9.3802 0.2237 19.0526
BT-549 GDSC1; GDSC2; CTRP2 3.357 7.6093 2.1808 15.7326
HCC1954 GDSC1; GDSC2; CTRP2 3.4144 6.1972 2.8576 12.9159
Hs 578T GDSC1; GDSC2; CTRP2 3.4334 7.4467 2.3317 14.9396
HCC2157 GDSC1; GDSC2 3.4707 5.0001 2.6034 4.135
YMB-1-E GDSC2 3.6598 6.1721 2.1677 6.3812
MCF-7 GDSC1; GDSC2; CTRP2; CTRP1 3.7192 6.0331 3.2506 10.648
HCC1395 GDSC1; GDSC2; CTRP2 3.7343 5.6276 3.4217 9.8631
HCC1187 GDSC1; GDSC2 3.7762 6.0186 2.3309 5.0708
OCUB-M GDSC1; GDSC2 3.793 5.8437 2.4288 4.4233
ZR-75-1 CTRP2 3.8019 6.2105 3.257 10.316
HCC2218 GDSC1; GDSC2; CTRP2 3.837 5.3146 3.6442 8.7321
MRK-nu-1 GDSC1; GDSC2 3.8535 6.8412 1.9832 7.0443
UACC-812 GDSC2 3.8623 6.7847 2.0176 6.809
COLO 824 GDSC1; GDSC2 3.8844 7.5046 1.6789 8.8501
MDA-MB-453 GDSC1; GDSC2; CTRP2 3.9226 5.2294 3.765 8.0331
Evsa-T GDSC1; GDSC2 3.996 5.595 2.686 2.4366
EFM-192A GDSC1; GDSC2 4.1794 7.7581 1.7715 7.5652
HCC70 GDSC1; GDSC2 4.189 7.612 1.8495 7.0688
ZR-75-30 GDSC1; GDSC2; CTRP2 4.3564 9.3962 2.2715 13.0254
MDA-MB-468 GDSC1; GDSC2; CTRP2 4.4378 8.6904 2.6941 11.1085
HCC1428 GDSC1; GDSC2; CTRP2 4.4393 6.6355 3.7016 6.9321
CAL-85-1 GDSC1; GDSC2; CTRP2 4.4652 8.0749 3.023 9.6833
KPL-1 CTRP2 4.4699 4.9133 4.4478 3.903
MDA-MB-361 GDSC1; GDSC2; CTRP2 4.4807 6.7307 3.6952 6.8618
MDA-MB-415 GDSC2 4.4964 6.8168 2.4291 3.013
BT-474 GDSC1; GDSC2 4.5003 7.9064 1.9218 5.9558
HCC38 GDSC1; GDSC2; CTRP2 4.6567 9.3556 2.5578 11.2102
HCC202 GDSC1; CTRP2 4.7941 7.3943 3.6548 6.3427
MDA-MB-175-VII GDSC1; GDSC2 4.8276 6.387 2.7887 0.8061
HCC1500 GDSC1; GDSC2; CTRP2 4.8377 8.9451 2.9192 9.3356
HCC1419 GDSC1; GDSC2; CTRP2 4.8672 10.3491 2.243 12.0782
UACC-893 GDSC1; GDSC2 4.8855 12.8239 -0.1974 16.6666
HCC1143 GDSC1; GDSC2; CTRP2 4.8962 8.8695 3.007 8.8512
T-47D GDSC1; GDSC2; CTRP2 4.921 8.4618 3.2318 7.8593
CAL-120 GDSC1; GDSC2; CTRP2 4.9618 8.3532 3.3206 7.4059
MDA-MB-436 GDSC1; GDSC2 5.0026 12.0026 0.29 14.0109
EFM-19 GDSC1; GDSC2 5.0141 8.4799 1.9795 4.6473
HMC-1-8 CTRP2 5.0318 6.4646 4.3237 3.0536
BT-483 GDSC1; GDSC2 5.0375 10.7633 0.9158 10.6158
JIMT-1 GDSC1; GDSC2; CTRP2 5.2516 8.1313 3.6701 5.3889
MDA-MB-330 GDSC2 5.3051 9.3242 1.7683 5.3207
CAMA-1 GDSC1; GDSC2; CTRP2 5.3253 7.7746 3.9057 4.2708
MFM-223 GDSC1; GDSC2 5.4327 11.0913 1.0241 9.1983
HCC1599 GDSC2 5.8454 7.5641 2.7644 0.3056
Hs 578Bst CTRP2 5.8964 8.4382 3.9943 3.015
HDQ-P1 GDSC1; GDSC2; CTRP2 6.2837 11.547 2.7592 7.4433
HCC1937 GDSC1; GDSC2; CTRP2 7.2357 12.9699 2.7253 6.2173
BT-20 GDSC1; GDSC2; CTRP2 8.5129 16.3334 1.9621 7.4608
BT 239 CTRP2 0.0644 4.1035 -0.1655 33.9151
BT164 CTRP2 2.9343 7.165 1.9486 17.7412
BT 172 CTRP2 3.0986 13.8429 -1.0658 27.5254
BT 428 CTRP2 3.6114 6.1837 3.0699 11.5575
BT 145 CTRP2 3.7032 7.4344 2.6062 13.1658
BT 248 CTRP2 3.7518 8.8636 1.9738 15.5967
BT 416 CTRP2 3.7718 8.3522 2.2389 14.4838
BT147 CTRP2 3.9675 17.5301 -2.1172 28.1555
BT 231 CTRP2 4.0387 7.6301 2.8408 11.4035
BT 286 CTRP2 4.1517 6.8818 3.3061 9.2343
BT 139 CTRP2 4.2175 8.8575 2.4114 12.7569
BT 271 CTRP2 4.3053 7.7597 3.0305 10.0072
BT 216 CTRP2 4.3344 7.0197 3.4168 8.3476
BT 112 CTRP2 4.4419 9.1446 2.4728 12.0143
BT 440 CTRP2 4.6119 6.541 3.9109 5.6706
BT 245 CTRP2 4.6392 7.5736 3.4281 7.6184
BT 131 CTRP2 4.7624 6.4612 4.0892 4.5949
BT 232 CTRP2 5.0188 7.8296 3.6304 5.9929
BT 333 CTRP2 5.0325 5.9794 4.567 2.0299
BT 159 CTRP2 5.066 7.0661 4.0514 4.1323
BT 422 CTRP2 5.1804 7.5851 3.8856 4.6147
BT 224 CTRP2 5.2471 10.7547 2.3563 10.8751
BT 320 CTRP2 5.3263 7.2413 4.1711 3.1614
BT 187 CTRP2 5.3362 8.8383 3.3848 6.432
BT 359 CTRP2 5.4641 8.4159 3.6944 4.9141
BT 328 CTRP2 5.5017 6.7953 4.5144 1.4841
BT 444 CTRP2 5.5047 12.8939 1.4963 13.8247
BT 482 CTRP2 5.5635 7.0405 4.4388 1.7009
BT 330 CTRP2 5.6037 9.4766 3.2754 6.4217
BT 228 CTRP2 5.7485 12.4533 1.9092 11.763
BT 498 CTRP2 5.8716 7.8834 4.2408 2.075
BT 179 CTRP2 6.2188 12.8691 2.0625 10.3459
BT 504 CTRP2 6.3997 11.1339 3.0418 6.1266
BT 340 CTRP2 6.5472 12.9511 2.2628 9.024
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.9352 4.9455 3.8594 7.6526
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-201 CTRP2 1.1427 12.1251 -7.4051 18.7083
H4 GDSC1; GDSC2 1.1699 7.8897 -0.9339 31.6355
D283 Med GDSC1; GDSC2; CTRP2 2.4231 5.717 1.9754 19.063
CAS-1 GDSC1; GDSC2; CTRP2 3.2972 5.944 2.834 13.3302
D-423MG GDSC1; GDSC2 3.3294 5.7012 2.1385 7.4699
LN-18 GDSC1; GDSC2; CTRP2 3.4817 4.055 3.4804 10.4154
LNZTA3WT4 GDSC1; GDSC2 3.5787 6.5452 1.919 8.157
D-336MG GDSC1; GDSC2 3.5825 9.1628 0.6157 15.9412
Hs 683 GDSC1; GDSC2; CTRP2 3.636 8.2357 2.1635 15.112
A-172 GDSC1; GDSC2; CTRP2 3.6913 8.8218 1.9364 15.889
Onda 10 GDSC1; GDSC2 3.7745 7.9122 1.3922 10.8894
SK-MG-1 GDSC1; GDSC2 3.7796 6.896 1.9005 7.7445
LN-405 GDSC1; GDSC2 3.818 6.1717 2.2863 5.2472
KINGS-1 GDSC1; GDSC2 3.932 8.6465 1.1494 11.9251
GaMG GDSC1; GDSC2; CTRP2; CTRP1 3.9422 5.4654 3.7093 8.2722
D-566MG GDSC1; GDSC2 3.9672 6.8413 2.0668 6.2519
M059J GDSC1; GDSC2 3.9748 10.9881 0.0185 17.9629
SNU-466 CTRP2 3.9973 4.7603 3.9648 7.0866
D-245MG GDSC2 4.1402 10.1002 0.5882 14.5641
SF539 GDSC1; GDSC2; CTRP2 4.1801 5.2681 4.0318 6.2888
KNS-60 CTRP2 4.1821 5.1253 4.0801 6.1047
U-118MG GDSC1; GDSC2; CTRP2 4.2625 11.7345 1.0273 18.1151
YKG-1 GDSC1; GDSC2; CTRP2 4.2665 6.9984 3.3621 8.7313
D-247MG GDSC1; GDSC2 4.2916 9.2887 1.103 11.2832
M059K CTRP2 4.3064 12.2578 0.8056 18.8324
AM-38 GDSC1; GDSC2 4.3168 11.1948 0.1807 16.2437
KNS-81-FD GDSC1; GDSC2 4.338 7.9665 1.7822 7.1397
GOS-3 CTRP2 4.3676 12.8485 0.565 19.5573
D-392MG GDSC1; GDSC2 4.3827 7.9042 1.8432 6.6742
PFSK-1 GDSC1 4.4576 9.5269 1.1075 13.2121
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 4.4629 8.016 1.8442 6.4961
GI-1 GDSC1; GDSC2 4.4789 8.4932 1.6255 7.7653
D-502MG GDSC1; GDSC2 4.5082 10.1937 0.8175 12.3762
MOG-G-CCM GDSC1; GDSC2 4.5506 10.1253 0.8819 11.9151
Onda 11 GDSC1; GDSC2 4.5983 7.4192 2.2141 4.0543
MOG-G-UVW GDSC1; GDSC2 4.6221 10.8231 0.592 13.3335
DBTRG-05MG GDSC1; GDSC2 4.6325 8.9512 1.5105 8.1088
KG-1-C CTRP2 4.7041 6.6221 3.9567 5.274
D-263MG GDSC1; GDSC2 4.7941 12.2416 0.0216 15.8407
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 4.8045 8.4603 3.1418 8.5531
NMC-G1 GDSC1; GDSC2; CTRP2 4.8055 7.4732 3.6256 6.4412
KALS-1 GDSC1; GDSC2 4.877 9.3149 1.5013 7.6451
SF295 GDSC1; GDSC2; CTRP2; CTRP1 4.8826 9.0452 2.917 9.3354
U-251MG GDSC1; GDSC2; CTRP2 4.9327 5.8545 4.5429 2.3339
D-542MG GDSC1; GDSC2 4.9648 11.501 0.5075 12.9757
SW1088 GDSC1; GDSC2; CTRP2 4.9918 11.5218 1.7617 13.7714
ONS-76 GDSC1; GDSC2; CTRP2 5.0004 8.461 3.2993 7.4197
SF268 GDSC1; GDSC2; CTRP2 5.0612 7.3272 3.9169 4.7068
T98G GDSC1; GDSC2; CTRP2 5.1946 6.4755 4.4499 2.2238
YH-13 GDSC1; GDSC2; CTRP2 5.2385 10.84 2.3067 11.0947
GMS-10 CTRP2 5.3779 10.3433 2.6675 9.3488
KNS-81 CTRP2 5.3858 7.2345 4.2192 2.8627
SNU-1105 CTRP2 5.4236 6.7002 4.5073 1.6222
Daoy GDSC1; GDSC2; CTRP2 5.4994 9.1406 3.362 6.2396
SNB-75 GDSC1; GDSC2; CTRP2 5.5484 8.5497 3.692 4.7829
SW1783 GDSC1; GDSC2; CTRP2 5.5508 12.3979 1.7806 12.6298
SNU-738 CTRP2 5.6641 8.6993 3.7041 4.5443
SNU-626 CTRP2 5.6783 10.7624 2.695 8.6997
GB-1 GDSC1; GDSC2; CTRP2 5.6867 7.8185 4.1493 2.6886
SNU-489 CTRP2 5.9092 7.6677 4.3642 1.5581
U-87MG ATCC GDSC1; CTRP2 5.9179 7.9202 4.2529 1.9705
42-MG-BA GDSC1; GDSC2; CTRP2 5.9359 9.2745 3.6184 4.4762
SF126 GDSC1; GDSC2; CTRP2 5.964 8.694 3.9174 3.2285
CCF-STTG1 CTRP2 6.0481 12.7275 2.0039 10.8649
8-MG-BA GDSC1; GDSC2; CTRP2 6.5557 12.4646 2.5059 8.0442
TM-31 CTRP2 6.8563 12.532 2.6818 6.9046
Becker GDSC1; GDSC2; CTRP2 6.896 12.2863 2.826 6.2812
DK-MG GDSC1; GDSC2; CTRP2 7.1634 17.4248 0.5191 14.517
KNS-42 GDSC1; GDSC2; CTRP2 8.8254 16.009 2.3006 5.8884
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 3.5245 8.0261 1.1365 13.1159
TGBC24TKB GDSC1; GDSC2 3.8901 6.9328 1.9653 7.0653
TGBC1TKB GDSC1; GDSC2 4.1255 6.4343 2.3738 4.0291
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 1.4703 8.1306 0.0171 28.7677
JHUEM-2 CTRP2; CTRP1 1.9222 6.0648 1.3165 23.0306
HEC-151 CTRP2; CTRP1 2.068 4.6676 1.8928 20.5109
JHUEM-1 CTRP2 3.8946 7.3697 2.8248 11.8135
RL95-2 GDSC2; CTRP2 3.9942 6.3787 3.3807 9.3253
EN GDSC1; GDSC2; CTRP2 4.025 7.9541 2.6721 12.126
JHUEM-3 CTRP2 4.0497 7.5406 2.8942 11.1592
KLE GDSC1; GDSC2; CTRP2; CTRP1 4.1065 6.6186 3.3912 9.0856
HEC-6 CTRP2; CTRP1 4.1143 5.6354 3.8286 7.3351
ESS-1 GDSC1; GDSC2; CTRP2 4.3421 7.8325 3.0291 9.9304
HEC-265 CTRP1 4.3564 5.2574 4.2302 11.0056
HEC-59 CTRP2; CTRP1 4.3889 7.1889 3.3945 8.398
HEC-50B CTRP2 4.483 6.4097 3.8517 6.2135
HEC-108 CTRP2; CTRP1 4.5241 6.9106 3.6567 7.0074
HEC-1-A CTRP2 4.5766 6.0502 4.1132 4.9215
MFE-319 GDSC1; GDSC2; CTRP2; CTRP1 4.9152 7.638 3.6477 6.209
HEC-251 CTRP2; CTRP1 5.2224 6.7303 4.3553 2.654
AN3-CA GDSC1; GDSC2; CTRP2 5.3569 12.6889 1.4793 14.1687
MFE-280 GDSC1; GDSC2 5.4397 7.4776 2.6329 0.9034
HEC-1-B CTRP2 5.5409 7.2988 4.2994 2.2931
EFE-184 CTRP2 5.5625 7.3867 4.2719 2.373
MFE-296 GDSC1; GDSC2; CTRP2 5.5796 8.8031 3.5903 5.1535
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 4.8894 7.7583 3.5655 6.6057
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC1; GDSC2 1.7856 5.6437 0.7209 21.4131
SW156 GDSC1; GDSC2 2.3465 7.2546 0.4934 20.5647
BB65-RCC GDSC1; GDSC2 2.8729 5.341 1.9175 10.2877
KTCTL-13 GDSC1; GDSC2 2.9932 8.4072 0.5004 18.3537
LB1047-RCC GDSC1; GDSC2 3.0333 8.8253 0.3262 19.1588
HA7-RCC GDSC1; GDSC2 3.1298 7.5181 1.0617 14.7297
NCC010 GDSC1; GDSC2 3.1318 5.8252 1.9085 9.5134
UO-31 GDSC1; GDSC2; CTRP2 3.1857 6.1758 2.6245 14.4431
TK-10 GDSC1; GDSC2 3.2517 6.2498 1.799 9.8386
RXF 393L GDSC1; GDSC2 3.4784 9.5806 0.322 17.8252
KMRC-3 CTRP2 3.486 6.0399 2.9969 12.1817
SW13 GDSC1; GDSC2 3.5284 6.3761 1.9633 8.0153
KMRC-20 GDSC1; GDSC2; CTRP2 3.6193 5.3659 3.3908 10.3101
LB2241-RCC GDSC1; GDSC2 3.6484 6.2265 2.132 6.6351
KTCTL-26A GDSC1; GDSC2 3.7245 11.6451 -0.5091 21.1276
CAL-54 GDSC1; GDSC2; CTRP2 3.7485 10.7073 1.0717 19.1045
A-704 GDSC2 4.0893 6.3587 2.3856 4.0329
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 4.171 6.1367 3.6748 7.7869
BFTC-909 GDSC1; GDSC2; CTRP2 4.1994 5.8457 3.8253 7.0296
KTCTL-1M GDSC1; GDSC2 4.2408 11.1185 0.1605 16.5435
ACHN GDSC1; GDSC2; CTRP2 4.3179 8.7324 2.5647 11.9044
VMRC-RCW GDSC2; CTRP2; CTRP1 4.3537 5.628 4.0837 5.6954
KTCTL-195 GDSC1; GDSC2 4.4007 6.9444 2.3114 3.857
TUHR4TKB CTRP2 4.4034 5.2767 4.2701 4.7514
NCC021 GDSC1; GDSC2 4.439 8.1745 1.7517 7.1
TUHR14TKB CTRP2 4.5283 8.6065 2.8168 10.4046
LB996-RCC GDSC1; GDSC2 4.5968 12.1665 -0.088 16.856
SNU-1272 CTRP2 4.6347 6.3397 4.0301 5.1259
769-P GDSC1; GDSC2; CTRP2 4.7343 6.8035 3.8947 5.4665
A-498 GDSC1; GDSC2 4.7422 14.2316 -0.9992 20.4993
TUHR10TKB CTRP2 4.8023 16.2725 -0.7727 22.9263
SN12C GDSC1; GDSC2 4.8234 7.4317 2.3424 2.9612
786-O GDSC1; GDSC2; CTRP2 4.8648 7.0923 3.8672 5.306
KTCTL-21 GDSC1; GDSC2 5.0084 9.7168 1.3972 7.9739
Caki-2 CTRP2 5.3529 7.4446 4.0907 3.4511
OS-RC-2 GDSC1; GDSC2; CTRP2 5.514 8.1558 3.8607 4.1394
KMRC-1 GDSC1; GDSC2; CTRP2 5.6378 14.9003 0.6018 16.8746
KMRC-2 CTRP2 6.4586 14.3723 1.5001 12.1311
VMRC-RCZ GDSC1; GDSC2; CTRP2 6.584 11.8464 2.8253 6.7256
Caki-1 GDSC1; GDSC2; CTRP2 8.0116 14.673 2.4209 6.3903
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 GDSC2; CTRP1 0.0013 1.9848 -0.0053 43.2431
SNU-503 CTRP2 2.0459 11.0518 -0.7172 32.8647
SNU-81 GDSC1; GDSC2; CTRP1 2.1134 4.5534 1.967 25.8135
CL-40 CTRP1 2.3452 4.9711 2.1209 39.9777
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 2.6615 6.3089 2.0199 18.291
CCK-81 GDSC1; GDSC2 2.9044 5.1984 2.0164 9.5646
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 2.9345 5.8565 2.4825 15.7702
SNU-C4 CTRP2; CTRP1 3.1163 6.0704 2.5969 14.8233
HT115 GDSC1; GDSC2; CTRP2; CTRP1 3.1879 4.3255 3.1607 12.5446
SNU-C2B GDSC1; GDSC2 3.2747 7.8413 1.0227 14.5194
T84 GDSC1; GDSC2; CTRP2 3.4973 4.9081 3.3912 10.675
LoVo GDSC1; GDSC2; CTRP2; CTRP1 3.5015 5.007 3.3732 10.8125
COLO 320HSR GDSC1; GDSC2 3.5186 5.0053 2.6381 3.7907
CL-34 CTRP1 3.5345 4.7847 3.4613 22.3157
LS180 GDSC1; GDSC2; CTRP2; CTRP1 3.5665 7.172 2.597 13.6264
SNU-61 GDSC1; GDSC2; CTRP2; CTRP1 3.598 5.1029 3.4523 10.2336
OUMS-23 CTRP2 3.6797 4.3607 3.6722 9.117
KM12 GDSC1; GDSC2; CTRP2; CTRP1 3.6822 5.5602 3.3949 10.1986
COLO205 GDSC1; GDSC2; CTRP2 3.7952 4.4095 3.7889 8.3434
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 3.7995 5.8384 3.4141 9.7969
LS513 GDSC1; GDSC2; CTRP2 3.8066 5.4908 3.5499 9.1728
SW837 GDSC1; GDSC2 3.8453 5.8919 2.4427 4.217
SNU-407 GDSC1; GDSC2; CTRP2 3.8511 5.7177 3.5118 9.1921
C2BBe1 GDSC1; GDSC2; CTRP2 3.856 6.2051 3.3154 9.9433
SW948 GDSC1; GDSC2; CTRP2; CTRP1 3.9334 5.2083 3.7868 8.0095
SNU-1033 CTRP2 3.9424 5.374 3.738 8.0759
SW48 GDSC1; GDSC2; CTRP2 3.9844 5.981 3.5444 8.7032
SNU-1040 CTRP1 4.0035 6.5412 3.3234 20.5443
SNU-C5 GDSC1; GDSC2; CTRP2; CTRP1 4.0627 7.0633 3.1407 10.2065
NCI-H747 GDSC1; GDSC2; CTRP2 4.1331 6.5936 3.4224 8.8083
SNU-C1 GDSC1; GDSC2; CTRP2 4.1426 5.9712 3.7125 7.6238
NCI-H508 GDSC1; GDSC2; CTRP1 4.1611 5.3772 3.9769 8.5246
SW1463 GDSC1; GDSC2 4.2263 7.1596 2.0944 5.4988
SW626 GDSC1; GDSC2 4.3016 7.3603 2.0493 5.6094
HCC2998 GDSC1; GDSC2 4.3123 6.2819 2.5632 2.5739
SNU-C2A CTRP2; CTRP1 4.3209 6.3623 3.7227 7.2175
GP5d GDSC1; GDSC2 4.3566 6.5758 2.4551 3.1088
RKO GDSC1; GDSC2; CTRP2; CTRP1 4.371 6.6585 3.6324 7.4636
LS1034 GDSC1; GDSC2; CTRP2 4.4217 5.5008 4.2024 4.9599
GP2d CTRP2 4.6384 10.0718 2.1848 12.7823
SW1116 GDSC1; GDSC2 4.6395 6.7041 2.5616 2.0741
HCC-56 CTRP2 4.6806 5.1468 4.6153 2.6577
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 4.689 5.3865 4.5351 3.0354
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 4.7126 5.7837 4.3789 3.6017
COLO 320 CTRP2; CTRP1 4.7199 7.5311 3.5301 7.1049
DiFi GDSC1; GDSC2 4.9703 8.1994 2.0815 4.1529
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 5.0495 5.9912 4.5848 2.0089
HCT 15 GDSC1; GDSC2; CTRP2 5.096 9.657 2.781 9.4051
CL-11 GDSC1; GDSC2 5.0979 7.4911 2.4652 1.9543
SW1417 GDSC1; GDSC2; CTRP2 5.1032 8.9966 3.117 7.9862
HCT 8 CTRP2; CTRP1 5.13 6.2637 4.5146 2.1521
SNU-283 GDSC2 5.1751 6.7066 2.8148 0.4734
DLD-1 CTRP2 5.2104 6.3148 4.5417 1.8135
LS411N GDSC1; GDSC2; CTRP2 5.2498 6.537 4.4616 2.0809
LS123 GDSC1; GDSC2; CTRP2; CTRP1 5.3084 6.8188 4.3772 2.4158
SW620 GDSC1; GDSC2; CTRP2; CTRP1 5.3721 6.9829 4.3438 2.4504
SW480 CTRP1 5.5608 8.1958 3.8865 8.6295
SK-CO-1 GDSC1; GDSC2; CTRP2 5.6183 7.3708 4.3177 2.1084
SW403 CTRP1 5.6412 7.5429 4.2623 5.0956
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 5.9287 12.8519 1.8614 11.7059
CaR-1 GDSC1; GDSC2 6.6949 14.7499 0.1148 11.3835
NCI-H716 GDSC1; GDSC2; CTRP2 7.9761 17.2202 1.1925 10.9392
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 4.0287 6.5499 2.2523 4.9717
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLF CTRP2 0.6348 2.5898 -2.5843 0.5953
HuH-6 CTRP2 2.8878 4.3847 2.8326 14.5555
JHH-5 CTRP2 3.2984 5.9482 2.8337 13.3281
SNU-182 CTRP2 3.3574 4.6216 3.2991 11.4382
HuH-1 GDSC1; GDSC2; CTRP2 3.3979 7.6028 2.2247 15.455
JHH-1 GDSC1; GDSC2; CTRP2 3.4913 5.8544 3.0755 13.7266
HLE GDSC1; GDSC2 3.6821 8.5471 1.0031 13.4587
SNU-398 GDSC1; GDSC2; CTRP2; CTRP1 3.7997 5.5509 3.5248 9.3741
Hep-G2/C3A GDSC1; GDSC2 3.8394 5.4917 2.6321 3.0723
Li-7 CTRP2 3.937 5.3579 3.7377 8.0925
SNU-761 CTRP2 3.9704 5.1935 3.8284 7.6583
Huh-7 GDSC1; GDSC2 3.9941 7.8721 1.5798 9.1807
JHH-7 GDSC1; GDSC2 4.0585 9.2012 0.9714 12.6322
SNU-387 GDSC1; GDSC2; CTRP2 4.3232 9.0739 2.401 12.5668
Hep-G2 CTRP2; CTRP1 4.413 5.5131 4.1934 5.1091
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 4.431 7.0303 3.5111 7.8211
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 4.6758 8.1553 3.172 8.611
JHH-4 GDSC1; GDSC2; CTRP2 4.6981 9.0787 2.7319 10.4017
PLC/PRF/5 CTRP2 4.8392 7.8971 3.4436 7.1351
JHH-2 GDSC1; GDSC2; CTRP2 5.145 8.1257 3.5867 5.9355
SNU-423 GDSC1; GDSC2; CTRP2 5.1541 10.7202 2.2974 11.2937
JHH-6 GDSC1; GDSC2; CTRP2; CTRP1 5.4287 6.856 4.4467 1.9392
SK-HEP-1 GDSC1; GDSC2; CTRP2 5.6696 7.7573 4.167 2.6416
SNU-886 CTRP2 7.1002 8.789 4.4856 0.3413
SNU-475 CTRP2 7.228 8.5347 4.6246 0.0995
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 225 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2196 GDSC2; CTRP2 0.2636 10.0198 -2.0437 37.7074
NCI-H1184 CTRP2 1.667 5.3857 1.2599 23.9264
DV-90 CTRP2 1.7719 6.1569 1.1175 24.1226
NCI-H209 GDSC1; GDSC2 2.1841 6.8147 0.5557 20.8112
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 2.3459 5.3318 2.0193 19.2079
SCLC-21H CTRP1 2.4512 4.6193 2.3199 38.0583
NCI-H1568 GDSC1; GDSC2; CTRP2; CTRP1 2.4648 4.7272 2.3111 17.7959
NCI-H1963 GDSC1; GDSC2; CTRP1 2.6056 4.1544 2.5635 21.1471
DMS 79 GDSC1; GDSC2; CTRP2 2.6112 5.4204 2.2775 17.3937
NCI-H596 GDSC1; GDSC2; CTRP1 2.687 4.4691 2.6043 20.6314
SK-MES-1 GDSC1; GDSC2; CTRP2 2.717 4.8451 2.556 16.0639
NCI-H1703 GDSC1; GDSC2; CTRP2 2.7254 5.5838 2.3482 16.7963
NCI-H1944 GDSC1; GDSC2; CTRP2; CTRP1 2.7376 4.7477 2.6033 15.913
NCI-H1048 GDSC1; GDSC2; CTRP1 2.7676 5.3362 2.4775 20.8933
NCI-H1734 GDSC1; GDSC2; CTRP2 2.8152 5.1099 2.5934 15.6292
NCI-H1781 GDSC1; GDSC2; CTRP1 2.9382 4.5273 2.865 18.4432
COR-L95 GDSC1; GDSC2; CTRP2 2.9933 5.686 2.6029 15.068
NCI-H2073 CTRP1 2.9967 7.1617 2.0202 35.3921
NCI-H1437 GDSC1; GDSC2; CTRP1 3.0088 5.3193 2.7454 18.7143
IST-SL1 GDSC1; GDSC2 3.018 5.331 2.0541 8.9559
Lu-135 GDSC1; GDSC2 3.0567 6.4063 1.5535 11.966
COR-L32 GDSC2 3.0797 4.9987 2.2741 7.3739
NCI-H290 GDSC1; GDSC2 3.0842 5.8478 1.8558 9.9924
NCI-H146 GDSC1; GDSC2; CTRP2 3.1005 4.9716 2.9424 13.5016
NCI-H211 GDSC1; GDSC2; CTRP2 3.1036 4.8422 2.978 13.3647
NCI-H740 GDSC2 3.1101 8.6458 0.4815 18.0884
NCI-H526 GDSC1; GDSC2; CTRP2 3.1104 5.1348 2.9085 13.5939
NCI-H2347 GDSC1; GDSC2 3.1253 6.4277 1.6023 11.4503
DMS 273 GDSC1; GDSC2; CTRP2; CTRP1 3.1319 4.887 3.0003 13.2815
Lu-139 GDSC1; GDSC2 3.1387 4.8904 2.3802 6.5176
NCI-H1304 GDSC1 3.1727 7.109 1.3027 16.1957
SBC-1 GDSC1; GDSC2 3.1764 8.0225 0.8493 15.8268
NCI-H810 GDSC1; GDSC2; CTRP2; CTRP1 3.1837 4.7928 3.0785 12.8432
KNS-62 GDSC1; GDSC2; CTRP2; CTRP1 3.2009 4.86 3.0819 12.7778
LCLC-97TM1 GDSC1; GDSC2; CTRP1 3.2685 5.5535 2.9506 16.7608
VMRC-LCD GDSC1; GDSC2; CTRP2; CTRP1 3.3097 4.9395 3.1812 12.0882
NCI-H1693 GDSC1; GDSC2; CTRP2 3.3118 7.5877 2.1453 15.9883
NCI-H2286 CTRP1 3.3514 5.1909 3.1577 25.8327
DMS 53 GDSC1; GDSC2; CTRP2 3.3645 6.1199 2.8362 13.1356
COR-L88 GDSC1; GDSC2; CTRP1 3.3681 4.7322 3.2915 14.7857
COR-L303 GDSC2 3.3806 8.4302 0.8165 15.4006
NCI-H1792 GDSC1; GDSC2; CTRP2; CTRP1 3.3891 4.772 3.3062 11.3987
NCI-H2029 GDSC1; GDSC2; CTRP2; CTRP1 3.3941 5.6415 3.0552 12.3013
NCI-H2461 GDSC1; GDSC2 3.4163 8.0389 1.0416 13.9893
A-427 GDSC1; GDSC2 3.4393 5.0448 2.5562 4.5174
NCI-H441 GDSC1; GDSC2; CTRP1 3.4578 5.0206 3.3219 14.2905
NCI-H1975 GDSC1; GDSC2; CTRP2; CTRP1 3.4686 4.8714 3.3707 10.9227
Lu-99A GDSC1; GDSC2 3.4713 5.8503 2.18 6.8063
RERF-LC-Sq1 GDSC1; GDSC2 3.478 6.8338 1.6944 9.8397
NCI-H2810 GDSC1; GDSC2 3.5097 9.0805 0.5976 16.2509
NCI-H1688 GDSC1; GDSC2 3.5207 7.2607 1.5156 10.8281
NCI-H2009 GDSC1; GDSC2; CTRP2; CTRP1 3.526 6.2035 2.9775 12.2314
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 3.5286 7.5576 2.3827 14.577
NCI-H524 GDSC1; GDSC2 3.55 5.4263 2.4533 4.8714
NCI-H2795 GDSC1; GDSC2 3.5669 5.7409 2.3101 5.7284
EBC-1 GDSC1; GDSC2; CTRP2 3.5728 5.717 3.2151 11.1039
NCI-H250 GDSC2 3.5915 6.4258 1.9885 7.6858
COR-L23 GDSC1; GDSC2; CTRP1 3.6074 5.5435 3.3203 13.7295
NCI-H1666 GDSC1; GDSC2; CTRP1 3.6183 4.8616 3.5359 12.6756
NCI-H520 GDSC1; GDSC2; CTRP2 3.6209 5.2682 3.4245 10.1804
NCI-H1573 GDSC1; GDSC2; CTRP1 3.6293 4.3944 3.6181 12.2649
IST-SL2 GDSC1; GDSC2 3.6333 5.526 2.4674 4.5695
HCC44 GDSC1; GDSC2; CTRP2 3.6728 5.5462 3.3858 10.1739
SBC-3 GDSC1; GDSC2 3.6744 6.7386 1.8977 8.0346
NCI-H345 GDSC1; GDSC2 3.6804 5.3787 2.5749 3.7841
LC-2/ad GDSC1; GDSC2 3.6853 5.9654 2.2895 5.5528
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 3.6922 5.8682 3.2885 10.5756
NCI-H23 GDSC1; GDSC2; CTRP2; CTRP1 3.6955 6.3043 3.1122 11.2513
NCI-H647 GDSC1; GDSC2; CTRP2 3.6962 9.679 1.5259 17.4953
ABC-1 GDSC1; GDSC2 3.7082 6.296 2.1432 6.4107
CPC-N GDSC1; GDSC2 3.7281 6.0509 2.2794 5.5093
NCI-H2731 GDSC1; GDSC2 3.7364 7.2633 1.6851 9.1943
NCI-H1993 GDSC1; GDSC2 3.7395 6.5171 2.0575 6.8672
NCI-H2804 GDSC1; GDSC2 3.7499 6.7511 1.9496 7.5145
HCC1588 CTRP2 3.7646 5.9253 3.3372 10.1033
NCI-H1341 GDSC1; GDSC2; CTRP2 3.7688 5.5041 3.5044 9.4522
NCI-H2591 GDSC1; GDSC2 3.8022 6.0812 2.3192 5.0809
HCC1833 CTRP2; CTRP1 3.824 5.7926 3.4583 9.5593
NCI-H2087 GDSC1; GDSC2 3.8334 7.9802 1.4041 10.6615
Ms-1 GDSC1; GDSC2 3.8559 5.7904 2.4994 3.8448
NCI-H2373 GDSC1; GDSC2 3.8726 7.4892 1.6775 8.8886
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 3.884 5.9494 3.4581 9.3963
NCI-H2106 CTRP2 3.9024 6.4356 3.262 10.0337
NCI-H1299 GDSC1; GDSC2; CTRP2; CTRP1 3.9063 6.0157 3.4538 9.3529
NCI-H64 GDSC1; GDSC2 3.9114 5.9813 2.4457 4.0501
COR-L321 GDSC1; GDSC2 3.9149 6.1401 2.3712 4.4983
NCI-H1838 GDSC1; GDSC2; CTRP2 3.9175 5.7146 3.5835 8.7329
NCI-H748 GDSC2 3.9176 7.5905 1.6615 8.8728
EPLC-272H GDSC1; GDSC2; CTRP1 3.9691 6.9178 3.1163 13.5218
EMC-BAC-1 GDSC1; GDSC2 3.9747 9.4122 0.8022 13.8161
COR-L279 GDSC1; GDSC2; CTRP1 3.9782 5.2312 3.8283 9.9173
NCI-H1623 GDSC1; GDSC2; CTRP2 3.9833 7.7741 2.7188 12.0329
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 3.9835 4.9129 3.9217 7.3706
Lu-65 GDSC1; GDSC2; CTRP2 3.9839 6.167 3.4638 9.0218
COLO 699 CTRP2; CTRP1 4.0021 5.058 3.9058 7.3704
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 4.0184 5.4029 3.8137 7.6614
NCI-H1581 GDSC1; GDSC2; CTRP2 4.0234 6.6288 3.2969 9.5872
COR-L311 GDSC2 4.0243 8.3618 1.3607 10.43
NCI-H2803 GDSC1; GDSC2 4.0307 7.6943 1.6946 8.389
NCI-H510A GDSC1; GDSC2 4.0308 5.684 2.6665 2.4851
NCI-H2066 GDSC1; GDSC2 4.0327 6.6361 2.2133 5.201
NCI-H2369 GDSC1; GDSC2 4.0388 10.7193 0.2024 16.867
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 4.0402 8.2473 2.5526 12.6606
DMS 454 CTRP2 4.0425 6.5156 3.3678 9.2542
NCI-H3122 GDSC1; GDSC2 4.0446 6.5253 2.2752 4.797
NCI-H2291 GDSC1; GDSC2; CTRP2 4.05 6.9347 3.1815 9.9876
Calu-6 GDSC1; GDSC2; CTRP2; CTRP1 4.0506 6.5373 3.3725 9.3005
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 4.0729 5.6221 3.7899 7.598
NCI-H847 GDSC1; GDSC2 4.0744 5.6377 2.7148 2.1284
NCI-H82 GDSC1; GDSC2; CTRP1 4.0748 5.2104 3.94 9.023
NCI-H1836 GDSC1; GDSC2; CTRP1 4.088 4.9612 4.0244 8.5795
MOR/CPR CTRP2 4.0967 4.8327 4.0593 6.4418
NCI-H358 GDSC1; GDSC2; CTRP2 4.1078 6.2186 3.5678 8.2882
NCI-H1876 GDSC1; GDSC2; CTRP1 4.1113 5.158 3.9961 8.6197
NCI-H522 GDSC1; GDSC2; CTRP2 4.1237 6.8444 3.2962 9.3425
LK-2 GDSC1; GDSC2 4.1258 6.9671 2.118 5.5752
SK-LU-1 GDSC1; CTRP2; CTRP1 4.1298 6.0111 3.6878 7.8425
NCI-H889 CTRP2 4.1398 5.2596 3.991 6.558
NCI-H1930 CTRP1 4.1462 5.6999 3.8362 15.4904
ChaGo-K-1 GDSC1; GDSC2; CTRP2; CTRP1 4.155 7.8954 2.8314 11.2532
Lu-165 GDSC1; GDSC2 4.1619 6.2546 2.4826 3.3108
NCI-H2405 GDSC1; GDSC2; CTRP2; CTRP1 4.162 6.3655 3.5626 8.2577
HCC95 CTRP2 4.1915 5.2462 4.0516 6.1817
NCI-H1105 GDSC2; CTRP2; CTRP1 4.1966 7.5048 3.0596 10.2202
Lu-99 CTRP2 4.198 5.7273 3.874 6.8424
HCC4006 CTRP2; CTRP1 4.2025 6.2552 3.6535 7.7914
A-549 GDSC1; GDSC2; CTRP2; CTRP1 4.2335 6.5009 3.5718 8.0428
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 4.2696 5.1396 4.1742 5.5896
Calu-3 GDSC1; GDSC2; CTRP2; CTRP1 4.2709 5.9351 3.8661 6.7697
NCI-H446 GDSC1; GDSC2; CTRP2 4.2941 6.1339 3.7943 6.9083
HCC33 GDSC2 4.3022 7.3262 2.066 5.5079
NCI-H835 GDSC1; GDSC2 4.313 8.0522 1.7232 7.5511
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 4.3348 5.7508 4.012 6.0265
NCI-H69 GDSC1; GDSC2 4.3431 7.0262 2.2361 4.4097
NCI-H322 CTRP2 4.3446 7.2334 3.3233 8.7086
NCI-H1092 GDSC1; GDSC2; CTRP2 4.3581 6.3703 3.7487 6.9339
LK2 CTRP2 4.38 4.9621 4.34 4.5648
NCI-H2172 GDSC1; GDSC2; CTRP1 4.3893 5.3248 4.2415 6.4077
NCI-H1373 CTRP2 4.3896 6.5289 3.7046 7.0374
COR-L51 CTRP2; CTRP1 4.3899 9.0431 2.485 12.1555
NCI-H513 GDSC1; GDSC2 4.394 6.6445 2.4463 3.0927
NCI-H2228 GDSC1; GDSC2; CTRP2 4.4136 7.3751 3.3191 8.5688
Sq-1 CTRP2; CTRP1 4.433 6.0791 3.9651 5.9618
T3M-10 CTRP2; CTRP1 4.4368 7.4035 3.335 8.5351
RERF-LC-Ad2 CTRP2 4.4406 8.6884 2.6976 11.0877
NCI-H2141 GDSC1; GDSC2; CTRP1 4.4756 5.2011 4.3785 5.4299
HOP-92 GDSC1; GDSC2; CTRP2 4.491 7.5516 3.3043 8.4572
NCI-H3255 GDSC1; GDSC2; CTRP1 4.495 5.4555 4.3033 5.7269
NCI-H2818 GDSC1; GDSC2 4.4968 7.851 1.9458 5.8202
NCI-H2171 GDSC2 4.5038 6.0523 2.7705 1.2121
LB647-SCLC GDSC1; GDSC2 4.5383 8.5763 1.6263 7.6301
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 4.5674 9.7179 2.3081 12.5038
NCI-H292 GDSC1; GDSC2; CTRP2 4.5829 6.4554 3.9251 5.6784
HCC1359 CTRP1 4.626 4.9737 4.6067 6.3263
HCC2279 CTRP2 4.6556 6.9986 3.727 6.3368
NCI-H1869 GDSC1; CTRP2 4.6946 7.0963 3.7141 6.3058
NCI-H187 GDSC1 4.7106 8.3419 1.8535 7.3415
LOU-NH91 GDSC1; GDSC2; CTRP2 4.7138 8.0667 3.2497 8.2066
NCI-H661 GDSC1; GDSC2; CTRP2 4.7238 6.9787 3.7986 5.8899
EMC-BAC-2 GDSC1; GDSC2 4.7429 10.0884 1.0373 10.594
LCLC-103H GDSC1; GDSC2; CTRP2 4.7549 6.2949 4.1641 4.2997
DMS 114 GDSC1; GDSC2; CTRP2 4.7716 7.4717 3.5965 6.6335
LUDLU-1 CTRP2 4.7763 5.4869 4.5733 2.5666
NCI-H727 GDSC1; GDSC2; CTRP2 4.7856 8.7065 2.9935 9.1305
NCI-H2135 GDSC1; GDSC2 4.809 6.6487 2.6735 1.3141
NCI-H2869 GDSC1; GDSC2 4.8145 9.2336 1.4984 7.7912
NCI-H2085 GDSC1; GDSC2; CTRP2 4.8318 6.3619 4.201 3.978
UMC-11 GDSC1; GDSC2 4.847 11.3517 0.4962 13.308
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 4.8481 6.8473 3.9745 4.8908
NCI-H650 GDSC1; GDSC2; CTRP2; CTRP1 4.8841 6.3011 4.2867 3.5961
NCI-H838 GDSC1; GDSC2; CTRP2 4.8855 7.7771 3.5435 6.6224
NCI-H1155 GDSC1; GDSC2; CTRP2 4.9282 7.2678 3.8344 5.3149
Lu-134-A GDSC1; GDSC2 4.9543 9.2911 1.5635 7.1304
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 4.9699 8.5926 3.2174 7.905
NCI-H1770 GDSC1; GDSC2 4.9728 6.7377 2.7153 0.9713
HCC2108 CTRP2; CTRP1 4.9809 6.6545 4.1952 3.78
RERF-LC-KJ GDSC1; GDSC2; CTRP1 4.9834 7.4397 3.805 6.9495
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 4.9847 6.4593 4.2959 3.3497
NCI-H1339 CTRP2 4.9853 8.4821 3.276 7.5469
NCI-H2595 GDSC1; GDSC2 4.9877 10.1533 1.1749 9.2785
NCI-H1563 GDSC1; GDSC2; CTRP2 5.0252 11.5537 1.7738 13.6576
HCC2935 CTRP2; CTRP1 5.0441 7.1475 4.0022 4.466
NCI-H720 GDSC1; GDSC2 5.0451 6.3044 2.9107 0.2776
NCI-H1648 GDSC1; GDSC2 5.0775 13.2457 -0.2638 16.519
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 5.0954 12.1465 1.5455 14.4888
BEN GDSC1; GDSC2; CTRP2 5.1057 8.5942 3.3204 7.1284
LC-1/sq GDSC1; GDSC2 5.1182 13.4009 -0.3103 16.6372
NCI-H2126 CTRP2 5.1252 7.9091 3.6788 5.5858
NCI-H1915 GDSC1; GDSC2; CTRP2; CTRP1 5.1545 10.7934 2.2709 11.4774
NCI-H1355 GDSC1; GDSC2; CTRP1 5.2045 7.526 3.9445 5.6572
SW1271 GDSC1; GDSC2; CTRP2 5.228 7.3646 4.0335 3.9076
NCI-H322M GDSC1; GDSC2 5.2346 7.383 2.5774 1.2977
NCI-H2170 GDSC1; GDSC2; CTRP2 5.3267 9.9989 2.7982 8.8999
HOP-62 GDSC1; GDSC2; CTRP2 5.3319 9.6315 2.9858 8.1087
HCC366 GDSC1; GDSC2; CTRP2 5.3427 8.0427 3.786 4.7411
NCI-H1395 CTRP2 5.3637 12.9445 1.3572 14.6246
SHP-77 GDSC1; GDSC2; CTRP2 5.3716 7.9734 3.8428 4.4533
RERF-LC-MS GDSC1; GDSC2; CTRP2 5.3843 11.3038 2.1933 11.284
RERF-LC-Ad1 CTRP2 5.4542 6.5323 4.608 1.1778
EKVX GDSC1; GDSC2; CTRP2 5.4836 8.0917 3.8695 4.1529
NCI-H2444 GDSC1; GDSC2; CTRP2 5.523 7.4782 4.1996 2.7269
NCI-H2227 GDSC1; GDSC2 5.5237 7.5196 2.6529 0.7737
SBC-5 GDSC1; GDSC2; CTRP2 5.5872 9.2439 3.3781 6.023
RERF-LC-A1 CTRP2 5.6138 8.1393 3.942 3.6438
NCI-H2722 GDSC1; GDSC2 5.6145 12.5476 0.4515 11.8458
NCI-H1650 GDSC1; GDSC2; CTRP2 5.6227 8.6028 3.7212 4.5404
NCI-H1436 GDSC1; GDSC2 5.6384 7.1002 2.8506 0.2022
HCC78 GDSC1; GDSC2; CTRP2 5.6469 7.649 4.2036 2.5267
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 5.6627 10.1915 2.9768 7.6389
HCC1438 CTRP2 5.7516 9.212 3.5166 5.1787
COR-L105 GDSC1; GDSC2; CTRP2 5.7868 9.8012 3.2528 6.2114
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 5.8361 7.6698 4.3303 1.8454
IA-LM GDSC1; GDSC2; CTRP2 5.8771 9.8719 3.2845 5.9349
HCC1195 CTRP2; CTRP1 5.9382 7.4179 4.5065 1.0748
SW1573 GDSC1; GDSC2; CTRP2 5.9509 12.2519 2.1654 10.3866
PC-14 GDSC1; GDSC2; CTRP2 5.9561 9.3101 3.6153 4.4588
PaCa-3 GDSC1; GDSC2 6.0004 13.3984 0.303 11.8043
NCI-H1651 GDSC1; GDSC2; CTRP2 6.2039 14.5738 1.2082 13.6597
HCC1171 CTRP2 6.2175 9.5541 3.6763 3.8412
NCI-H196 GDSC1; GDSC2; CTRP2 6.2242 11.7565 2.6136 8.1262
NCI-H226 GDSC1; GDSC2; CTRP2 6.3922 9.1671 3.9686 2.4873
LC-1/sq-SF CTRP2 7.3708 16.1092 1.3104 11.3965
Calu-1 CTRP2 7.9305 15.8447 1.8186 8.7293
NCI-H1793 GDSC1; GDSC2; CTRP2 8.5227 17.5986 1.3755 9.547
Hs 888.Lu CTRP2 4.564 9.7286 2.2908 12.504
⏷ Show the Full List of 225 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 3.9005 5.6084 2.6175 3.032
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 -1.7318 4.6585 -2.249 45.8337
H-STS CTRP2 1.147 2.6585 1.1423 25.9809
P-STS CTRP2 2.8857 5.9202 2.4024 16.1307
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.4381 7.2922 1.3796 21.2543
COV434 CTRP2; CTRP1 1.325 4.3508 1.1532 25.4387
Caov-3 GDSC2; CTRP2; CTRP1 2.595 5.0482 2.3729 17.1749
A2780 GDSC1; GDSC2; CTRP1 3.1155 5.283 2.8729 17.7069
OVCAR-8 GDSC1; GDSC2; CTRP2; CTRP1 3.2997 8.0015 1.9499 16.8686
ES-2 GDSC1; GDSC2 3.4801 4.8034 2.7085 3.4477
OVK18 GDSC1; GDSC2; CTRP2; CTRP1 3.543 8.1638 2.1142 15.6141
COV644 CTRP2; CTRP1 3.5702 5.3629 3.3421 10.7202
Caov-4 GDSC1; GDSC2 3.6327 5.738 2.3621 5.2314
OVKATE GDSC1; GDSC2; CTRP1 3.6982 4.6351 3.6645 11.7749
COV362 CTRP2; CTRP1 3.8054 5.6319 3.5007 9.4492
OVCAR-3 GDSC1; GDSC2 3.9812 8.9231 1.05 12.3786
JHOS-4 GDSC1; GDSC2; CTRP1 4.055 5.5023 3.8168 9.6881
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 4.1769 5.7653 3.8414 7.115
RMUG-S CTRP1 4.1832 5.7393 3.8589 15.0871
JHOC-5 CTRP2; CTRP1 4.1972 6.79 3.4009 8.8237
IGROV-1 GDSC1; GDSC2; CTRP1 4.2255 7.6525 3.0157 13.2568
OVCAR-5 GDSC1; GDSC2; CTRP2 4.3087 6.7509 3.5208 7.9816
ONCO-DG-1 CTRP2 4.3942 5.9915 3.9598 5.9916
OAW42 GDSC1; CTRP2; CTRP1 4.417 6.2209 3.8835 6.3311
SNU-119 CTRP2 4.4666 5.8861 4.0806 5.3246
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 4.4767 7.9807 3.0883 9.4695
OAW28 GDSC1; GDSC2; CTRP2 4.5641 8.0657 3.1169 9.0779
JHOS-2 GDSC1; GDSC2; CTRP2 4.5706 8.7514 2.7826 10.4567
SK-OV-3 GDSC1; GDSC2; CTRP2; CTRP1 4.6584 7.8597 3.3122 8.1449
TOV-112D GDSC1; GDSC2; CTRP2 4.6686 9.3775 2.5572 11.1881
DOV13 GDSC1; GDSC2; CTRP2 4.7272 7.0292 3.7766 5.9745
OVMANA CTRP1 4.7638 5.2029 4.6886 4.8023
OV7 CTRP2; CTRP1 4.7742 6.2744 4.2002 4.195
HEY A8 CTRP2; CTRP1 4.7929 7.9752 3.3735 7.6073
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 4.8252 10.1608 2.3107 11.9628
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 4.858 7.3197 3.7571 5.8668
TOV-21G GDSC1; GDSC2; CTRP2 4.8757 11.0115 0.6825 9.4205
Kuramochi GDSC1; GDSC2; CTRP2 5.0938 8.2391 3.488 6.447
JHOM-1 CTRP2; CTRP1 5.12 5.9233 4.6764 1.492
COV318 CTRP1 5.1232 5.7406 4.77 2.3488
OVTOKO GDSC1; GDSC2; CTRP2 5.1683 7.428 3.9542 4.3489
SNU-8 CTRP2 5.2022 6.1444 4.6197 1.5026
MCAS CTRP2 5.4132 7.5867 4.066 3.4532
ES2 CTRP2 5.434 7.1049 4.3181 2.3781
OC 314 GDSC1; GDSC2; CTRP2 5.5349 9.943 2.9909 7.7243
OVSAHO CTRP2 5.5814 8.3361 3.8218 4.1909
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 5.6262 7.0527 4.4858 1.5071
OVISE GDSC1; GDSC2; CTRP2 5.7749 10.0394 3.1264 6.7531
OV56 GDSC1; GDSC2; CTRP2 6.1693 7.5342 4.565 0.6267
SNU-840 CTRP2; CTRP1 6.3271 8.3616 4.3063 1.3958
FU-OV-1 GDSC1; GDSC2; CTRP2 6.9281 8.7815 4.4157 0.5722
EFO-21 GDSC1; GDSC2; CTRP2; CTRP1 7.8662 16.3692 1.5376 9.9137
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 3.1273 4.6044 3.0538 13.0235
Yamato-SS CTRP2 3.6398 4.5913 3.6073 9.468
TE 617.T CTRP2 0.725 3.2189 0.6756 28.9424
TE 441.T GDSC2; CTRP2 1.8823 3.9003 1.8254 21.259
G-402 GDSC1; GDSC2; CTRP2 2.0569 6.6135 1.2529 22.7974
EW-8 GDSC1; GDSC2 2.281 5.6001 1.2308 16.5719
G-401 GDSC1; GDSC2; CTRP2; CTRP1 2.465 5.0505 2.2304 18.0835
BT-16 CTRP2 2.562 3.9348 2.539 16.6154
A-204 GDSC1; GDSC2; CTRP2 2.6803 9.8081 0.489 23.8254
Rh41 GDSC1; GDSC2; CTRP2 2.812 4.6656 2.7001 15.2577
STS-0421 GDSC1; GDSC2 2.9348 5.6179 1.8372 10.5855
Tm87-16 CTRP2 3.0321 4.8803 2.8909 13.8964
TTC-709 CTRP2 3.2065 6.6714 2.4422 15.0932
SW982 GDSC1; GDSC2; CTRP2 3.388 9.9836 1.0877 19.8985
Rh18 GDSC1 3.5268 6.8269 1.7371 11.697
MFH-ino GDSC1; GDSC2 3.5754 6.3596 2.0089 7.6013
VA-ES-BJ GDSC1; GDSC2 3.5975 6.8305 1.7917 8.9027
GCT GDSC1; GDSC2; CTRP2 3.6725 7.3177 2.6298 13.1471
KYM-1 GDSC1; GDSC2; CTRP2 3.7847 8.0548 2.3935 13.828
MES-SA GDSC1; GDSC2; CTRP2 4.1011 6.1644 3.5851 8.2366
BT-12 CTRP2 4.1161 5.0362 4.0335 6.4732
Hs 633.T GDSC1; GDSC2 4.1703 11.7464 -0.2058 18.5165
Rh30 GDSC1; GDSC2 4.246 9.4937 0.9682 12.1721
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 4.3356 6.2799 3.7755 6.9681
Hs 729.T CTRP2 5.0409 12.4592 1.3341 15.3398
SW684 GDSC1; GDSC2 5.0538 12.2822 0.1903 14.3943
SK-UT-1 GDSC1; GDSC2; CTRP2 5.1751 7.5573 3.8952 4.5841
RKN GDSC1; GDSC2; CTRP2; CTRP1 5.44 7.0772 4.347 2.3299
RD GDSC1; GDSC2; CTRP2 5.4844 11.2015 2.3244 10.5663
SW872 GDSC1; GDSC2 5.4996 12.9416 0.1837 13.4299
SK-LMS-1 GDSC1; GDSC2; CTRP2 5.631 9.9309 3.0711 7.2246
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.9946 7.1968 3.9264 4.7964
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2052 GDSC1; GDSC2; CTRP2; CTRP1 2.5888 7.6881 1.3711 20.9493
MSTO-211H GDSC1; GDSC2; CTRP2; CTRP1 3.5516 5.7393 3.1884 11.3505
IST-Mes1 GDSC1; GDSC2; CTRP2 4.0147 8.6962 2.3026 13.6593
MPP 89 GDSC1; GDSC2; CTRP2 4.2283 7.0287 3.3107 9.0321
JL-1 CTRP2 4.4425 8.7287 2.6794 11.159
NCI-H28 GDSC1; GDSC2; CTRP2; CTRP1 4.6533 8.3875 3.0456 9.2684
NCI-H2452 GDSC1; GDSC2; CTRP2 5.3869 10.6595 2.517 9.9541
ACC-MESO-1 CTRP2 5.6648 7.2138 4.4229 1.6296
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2; CTRP2 1.5576 5.4898 1.1088 24.7988
VCaP GDSC1; GDSC2; CTRP2 2.0468 6.0856 1.4394 22.1423
22Rv1 GDSC1; GDSC2; CTRP2 3.5296 7.7639 2.2812 14.9005
PaCa-3 CTRP2; CTRP1 4.1006 5.3969 3.9046 7.084
PC-3 GDSC1; GDSC2 4.547 8.2894 1.7701 6.7587
NCI-H660 GDSC2 5.4314 6.9059 2.8425 0.2844
DU145 GDSC1; GDSC2; CTRP2 6.3486 12.0691 2.5507 8.1839
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2; CTRP2 3.8184 6.6024 3.1021 10.8863
YD-15 CTRP2 4.7775 6.6038 4.0325 4.7982
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 2.2042 3.5928 2.0187 12.2149
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1; GDSC2; CTRP2 2.0717 3.6155 2.0516 19.872
NUGC-3 GDSC1; GDSC2; CTRP2 2.8797 5.1419 2.6547 15.2117
NUGC-4 GDSC1; GDSC2; CTRP2; CTRP1 2.914 4.9733 2.7409 14.8786
TMK-1 GDSC1; GDSC2 2.9692 6.3866 1.4866 12.656
HSC-39 GDSC1; GDSC2 2.9915 4.6268 2.3771 7.0175
NCI-N87 GDSC1; CTRP2 3.0026 6.7443 2.1991 16.5865
AGS GDSC1; GDSC2; CTRP2; CTRP1 3.1037 5.5468 2.7745 14.1893
23132/87 GDSC1; GDSC2; CTRP2 3.2779 4.7639 3.1853 12.0875
Fu97 GDSC1; GDSC2; CTRP2; CTRP1 3.3084 4.9145 3.186 12.0751
GCIY GDSC1; GDSC2 3.3234 5.2277 2.3703 6.0211
SNU-16 GDSC1; GDSC2; CTRP2 3.4488 4.9649 3.3241 11.0644
GSS CTRP2 3.4799 4.2837 3.4698 10.4568
NCC-StC-K140 CTRP2 3.5538 5.1802 3.3786 10.5488
MKN28 GDSC1; GDSC2 3.6305 6.1308 2.1656 6.4705
Hs 746.T GDSC1; GDSC2; CTRP2 3.8105 6.1397 3.2961 10.1397
RF-48 GDSC1; GDSC2 3.823 6.3521 2.2014 5.7627
RERF-GC-1B GDSC1; GDSC2 3.8466 6.4721 2.1598 5.9641
SNU-1 GDSC1; GDSC2; CTRP2 3.9241 5.9707 3.4858 9.0937
IM95 GDSC1; GDSC2; CTRP2 3.9249 7.2022 2.9333 11.2997
ECC10 GDSC1; GDSC2; CTRP2 3.935 5.4883 3.6889 8.2816
SNU-620 CTRP2 4.0897 5.0478 4.0016 6.6688
SNU-5 GDSC1; GDSC2; CTRP2 4.1474 7.5735 2.972 10.6111
TGBC11TKB GDSC1; GDSC2 4.2746 7.222 2.0974 5.3777
SCH GDSC1; GDSC2 4.3072 9.4828 1.0191 11.729
SNU-601 CTRP2 4.3228 5.6307 4.0449 5.8401
MKN74 CTRP2; CTRP1 4.4521 5.8254 4.0996 5.3749
SNU-668 CTRP2 4.5666 6.1246 4.0682 5.129
KATO III GDSC1; GDSC2; CTRP2 4.6188 6.1454 4.1087 4.8398
HuG1-N CTRP2 4.6491 8.0653 3.1931 8.5791
KE-39 CTRP2 4.6654 8.7643 2.8599 9.9362
SK-GT-2 GDSC1; GDSC2 4.7197 9.8947 1.115 10.2059
OCUM-1 GDSC1; GDSC2 4.9275 6.6972 2.7106 1.0321
GSU CTRP2 4.9532 5.3466 4.8119 1.169
SNU-216 CTRP2 5.1073 7.6879 3.7746 5.2171
SNU-719 CTRP2 5.2401 12.1365 1.6601 13.6881
MKN7 GDSC1; GDSC2; CTRP2; CTRP1 5.3205 9.491 3.0569 7.912
SH-10-TC CTRP2; CTRP1 5.4811 6.555 4.6266 1.1443
ECC12 GDSC2; CTRP2 5.535 6.6108 4.6225 1.0199
LMSU CTRP2 5.567 10.5795 2.6994 8.8765
MKN1 GDSC1; GDSC2; CTRP2 6.5884 9.9563 3.7248 3.1788
MKN45 GDSC1; GDSC2; CTRP2 6.7605 7.8871 4.68 0.1182
SNU-685 CTRP2 4.7189 10.0525 2.2642 12.292
SNG-M GDSC1; GDSC2; CTRP1 5.4461 7.2728 4.2557 3.4611
SNU-1077 CTRP2 5.7787 7.8543 4.1942 2.38
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC1; GDSC2 2.1764 9.3756 -0.7055 26.8822
IHH-4 GDSC1; GDSC2 3.2395 7.2315 1.2981 12.9766
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 3.4992 7.5243 2.3619 14.6536
8305C GDSC1; GDSC2; CTRP2 3.7305 4.6156 3.7007 8.8545
SW579 CTRP2 3.7604 9.0612 1.8863 15.926
BHT-101 GDSC1; GDSC2; CTRP2 3.9426 5.1664 3.8065 7.8212
WRO GDSC1; GDSC2 4.0079 7.0889 1.975 6.7217
KMH-2 GDSC1; GDSC2 4.0828 6.9868 2.0784 5.9133
ASH-3 GDSC1; GDSC2 4.1817 7.1858 2.0511 5.8586
FTC-238 CTRP2 4.2756 9.3649 2.2142 13.4354
HTC-C3 GDSC1; GDSC2 4.3418 7.5836 1.9694 6.0042
TT GDSC1; GDSC2; CTRP2 4.3956 6.926 3.5202 7.7798
CAL-62 GDSC1; GDSC2; CTRP2 4.6662 5.5178 4.4485 3.3454
8505C GDSC1; GDSC2; CTRP2 4.8861 7.4423 3.7111 5.9175
FTC-133 GDSC1; GDSC2; CTRP2 5.184 10.4036 2.4802 10.485
B-CPAP GDSC1; GDSC2; CTRP2 5.5432 8.6294 3.6487 4.9712
CGTH-W-1 GDSC1; GDSC2; CTRP2 5.6939 9.1024 3.528 5.2242
TT2609-C02 GDSC1; GDSC2; CTRP2 6.048 11.7343 2.4945 8.8946
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 22 GDSC1; GDSC2; CTRP2 1.809 6.3408 1.0906 24.1097
KOSC-2 GDSC1; GDSC2 2.0745 7.4793 0.1301 23.4507
PCI-04B GDSC1; GDSC2 2.2526 7.1502 0.4571 21.0972
PCI-15A GDSC1; GDSC2 2.3908 5.9514 1.1687 16.5441
PCI-38 GDSC1 2.4536 6.3602 1.0299 21.089
HO-1-u-1 GDSC1; GDSC2 2.6889 4.7753 2.0181 10.3004
JHU-029 GDSC1; GDSC2 2.7614 5.0672 1.9473 10.4818
JHU-011 GDSC1; GDSC2 2.831 7.0251 1.0468 15.765
BICR 10 GDSC1 2.8333 5.5612 1.7729 14.073
BB30-HNC GDSC1; GDSC2 2.8349 5.9938 1.5612 12.6303
KON GDSC1; GDSC2 2.837 5.5133 1.7999 11.1407
SAT [Human HNSCC] GDSC1; GDSC2 2.8839 5.9449 1.6296 12.0455
PCI-06A GDSC1; GDSC2 2.8879 8.7281 0.2492 20.0256
BB49-HNC GDSC1 3.0878 6.6218 1.473 15.2919
BHY GDSC1; GDSC2; CTRP2 3.1801 4.9155 3.0436 12.8945
Detroit 562 GDSC1; GDSC2; CTRP2 3.3354 5.3864 3.0758 12.3103
BICR 18 CTRP2 3.3527 6.5155 2.6605 13.8495
CAL-33 GDSC1; GDSC2; CTRP2 3.434 5.9545 2.9756 12.4074
SAS GDSC1; GDSC2 3.445 6.8604 1.6542 10.1831
SCC-4 GDSC1; GDSC2; CTRP2 3.5309 5.7185 3.1697 11.395
SCC-25 GDSC1; GDSC2 3.6925 5.8684 2.3428 5.2016
DOK GDSC1; GDSC2 3.7001 11.2449 -0.329 20.3848
HO-1-N-1 GDSC1; GDSC2 3.7392 7.0001 1.818 8.3623
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 3.7567 8.1955 2.2993 14.2758
BICR 78 GDSC1; GDSC2 3.7916 8.0157 1.354 11.075
SKN-3 GDSC1; GDSC2 3.8421 6.6543 2.0669 6.5523
JHU-022 GDSC1; GDSC2 3.8738 8.4559 1.1991 11.7843
NCI-H3118 GDSC1; GDSC2 3.9264 6.5181 2.1953 5.5546
Ca9-22 GDSC1; GDSC2 3.9437 6.3701 2.2798 4.9944
BICR 16 CTRP2 3.9583 5.0893 3.8466 7.6279
PE/CA-PJ34 (clone C12) CTRP2 4.1393 9.1492 2.1963 13.81
BICR 6 CTRP2 4.2001 7.5094 3.053 10.1557
CAL-27 GDSC1; GDSC2; CTRP2 4.2387 8.0242 2.8393 10.9478
FaDu GDSC1; GDSC2; CTRP2 4.3173 8.4628 2.6969 11.3602
PCI-30 GDSC1; GDSC2 4.3615 8.2946 1.6397 7.9433
SNU-1214 CTRP2 4.3731 6.2134 3.8366 6.5407
LB771-HNC GDSC1; GDSC2 4.4556 7.035 2.3037 3.7995
PE/CA-PJ49 CTRP2 4.4626 10.5981 1.769 14.8277
SNU-1076 CTRP2 4.6909 5.909 4.291 3.9224
YD-10B CTRP2 4.714 6.0645 4.2383 4.085
YD-8 CTRP2 4.7513 6.3214 4.1478 4.3755
SNU-899 CTRP2 4.7731 7.1107 3.7773 5.874
SNU-46 CTRP2 4.8064 6.5735 4.0735 4.5647
BICR 31 GDSC2; CTRP2 4.8334 11.8057 1.4864 15.1695
SNU-1066 CTRP2 4.8343 6.4803 4.1446 4.2083
PE/CA-PJ41 (clone D2) CTRP2 4.8531 5.688 4.552 2.471
UPCI-SCC-090 GDSC1; GDSC2 4.8601 7.9654 2.1224 4.1123
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 4.8812 6.5951 4.1382 4.2231
HSC-3 GDSC1; GDSC2; CTRP2 5.0164 6.822 4.1321 3.889
SNU-1041 CTRP2 5.0785 6.7584 4.2156 3.4183
HSC-2 GDSC1; GDSC2; CTRP2; CTRP1 5.152 7.0059 4.1619 3.591
OSC-20 GDSC1; GDSC2 5.1664 14.5583 -0.843 18.8429
OSC-19 GDSC1; GDSC2 5.2279 6.8564 2.7804 0.5476
SCC-15 GDSC1; GDSC2 5.3213 7.1934 2.6915 0.7815
HSC-4 GDSC1; GDSC2; CTRP2 5.8195 8.5918 3.8677 3.6351
BICR 56 CTRP2 7.5394 8.8646 4.6215 0.0637
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC1; GDSC2; CTRP2 3.052 4.4926 2.9921 13.4778
253J-BV CTRP2 3.3432 5.2538 3.1267 12.0994
SW780 GDSC1; GDSC2 3.3506 5.2534 2.38 5.8806
CAL-29 GDSC1; GDSC2; CTRP2 3.4469 4.9791 3.3184 11.0902
RT-112 GDSC1; GDSC2 3.4694 7.7961 1.2065 12.855
U-BLC1 CTRP2 3.6552 5.5146 3.3781 10.2532
SW1710 GDSC1; GDSC2 3.7924 11.8043 -0.5339 21.0452
UM-UC-1 CTRP2 4.0551 10.411 1.4978 16.7829
RT-4 GDSC1; GDSC2; CTRP2; CTRP1 4.0702 6.383 3.4622 8.8921
JMSU-1 CTRP2 4.4053 5.835 4.0415 5.6368
HT-1197 GDSC1; GDSC2 4.503 6.9842 2.3564 3.4118
BC-3C CTRP2 4.5794 5.1669 4.4989 3.3859
5637 GDSC1; GDSC2; CTRP2; CTRP1 4.6282 8.1459 3.1432 8.9144
TCCSUP GDSC1; GDSC2; CTRP2 4.7708 6.7924 3.9331 5.2274
UM-UC-3 GDSC1; GDSC2; CTRP2; CTRP1 4.7969 6.8632 3.9301 5.2706
VM-CUB-1 CTRP2 4.8071 6.6298 4.0461 4.6778
SCaBER CTRP2 4.8765 7.6065 3.6208 6.3159
647V GDSC1; GDSC2; CTRP2 5.0082 10.5603 2.2563 11.7445
KMBC-2 CTRP2; CTRP1 5.1975 7.3074 4.0479 3.9857
639V GDSC1; GDSC2; CTRP2 5.2489 6.2985 4.5785 1.5973
J82 GDSC1; GDSC2; CTRP2 5.4272 8.4193 3.6644 5.1025
KU-19-19 GDSC1; GDSC2; CTRP2 5.4971 7.085 4.3723 2.0616
HT-1376 GDSC1; GDSC2; CTRP2; CTRP1 5.8016 7.5121 4.3822 1.6882
T24 GDSC1; GDSC2; CTRP2 6.3289 10.5375 3.2806 5.2679
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1; GDSC2 1.7255 7.3519 -0.1402 26.09
PA-1 GDSC1; GDSC2 2.012 4.4424 1.4839 16.1039
SW954 GDSC1; GDSC2 2.7952 5.5122 1.7619 11.5174
JAR GDSC1; GDSC2 2.8453 5.3447 1.8902 10.55
DSH1 GDSC1; GDSC2 3.1718 4.949 2.3801 6.414
OVMIU GDSC1; GDSC2 3.2152 6.8802 1.4531 12.101
BPH-1 GDSC1; GDSC2 3.2491 7.2782 1.2828 13.0404
NEC8 GDSC1; GDSC2 3.2533 5.8406 2.005 8.5371
C-4-I GDSC1; GDSC2 3.2593 7.2933 1.2838 13.0039
C-33 A GDSC1; GDSC2 3.2825 5.2724 2.3136 6.4994
NT2-D1 GDSC1; GDSC2 3.3728 5.1842 2.4328 5.483
HEY GDSC1; GDSC2 3.3978 6.0134 2.0388 7.9034
Ca Ski GDSC1; GDSC2 3.4413 8.0176 1.0728 13.7325
CAL-39 GDSC1; GDSC2 3.5282 5.5546 2.3724 5.4381
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 3.5511 5.2921 2.5207 4.4442
OVCA433 GDSC1; GDSC2 3.5934 7.2755 1.5666 10.3117
HT-3 GDSC1; GDSC2 3.6017 5.3443 2.5334 4.2356
PEO1 GDSC1; GDSC2 3.7372 5.6661 2.4753 4.2668
TC-YIK GDSC1; GDSC2 3.7768 5.9649 2.3577 4.9025
JHOS-3 GDSC1; GDSC2 3.803 5.6413 2.5346 3.7482
MS751 GDSC1; GDSC2 3.8155 5.5083 2.6077 3.2726
NCC-IT GDSC2 3.8546 6.0551 2.3698 4.6445
HEC-1 GDSC1; GDSC2 3.9749 6.1055 2.4296 4.0099
SW756 GDSC1; GDSC2 4.0244 7.5847 1.7439 8.1028
SiSo GDSC1; GDSC2 4.0256 7.2873 1.8907 7.1981
OV17R GDSC1; GDSC2 4.0321 6.4417 2.3069 4.6313
SKG-IIIa GDSC1; GDSC2 4.0605 7.1169 1.9992 6.4498
LB831-BLC GDSC1; GDSC2 4.0718 9.6095 0.7791 13.6894
SW962 GDSC1; GDSC2 4.3245 8.4186 1.5531 8.5469
SKN GDSC1; GDSC2 4.3333 10.65 0.4628 14.7394
UWB1.289 GDSC1; GDSC2 4.3365 7.6867 1.9163 6.3354
OVCA420 GDSC1; GDSC2 4.4212 6.7765 2.4021 3.2964
DoTc2 4510 GDSC1; GDSC2 4.4429 7.4346 2.108 4.9688
ME-180 GDSC1; GDSC2 4.5108 6.848 2.4235 3.0202
SiHa GDSC1; GDSC2 4.9595 9.7447 1.3514 8.3356
HeLa GDSC1; GDSC2; CTRP2 4.9613 5.6866 4.6517 1.8185
PWR-1E GDSC1; GDSC2 5.0951 8.8391 1.8637 5.1553
JEG-3 GDSC1; GDSC2 5.2892 13.2614 -0.119 15.3553
ACC-OV7 GDSC1; GDSC2 5.481 11.9271 0.6585 11.0546
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 ClinicalTrials.gov (NCT00676910) A Research Study of JNJ-26854165 to Determine the Safety and Dose in Patients With Advanced Stage or Refractory Solid Tumors.. U.S. National Institutes of Health.
2 Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.Nat Rev Drug Discov. 2016 Aug;15(8):533-50.
3 Serdemetan antagonizes the Mdm2-HIF1alpha axis leading to decreased levels of glycolytic enzymes. PLoS One. 2013 Sep 6;8(9):e74741.