Details of the Drug

General Information of Drug (ID: DMNZA4L)

Drug Name
Griffithsin
Synonyms GRFT
Indication
Disease Entry ICD 11 Status REF
Human immunodeficiency virus infection 1C62 Phase 1 [1]
Severe acute respiratory syndrome (SARS) 1D65 Preclinical [2]
Therapeutic Class
Antiviral Agents
Drug Type
Protein/peptide drug
Sequence
SLTHRKFGGSGGSPFSGLSSIAVRSGSYLDAIIIDGVHHGGSGGNLSPTFTFGSGEYISN
MTIRSGDYINISFETNMGRRFGPTYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQ
Y
Cross-matching ID
TTD ID
D0K6XI
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SARS-CoV spike glycoprotein (S) TTTL19V SPIKE_CVHSA Blocker [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT02875119) Study to Evaluate the Safety of Griffithsin in a Carrageenan Gel in Healthy Women
2 Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.