Details of the Drug

General Information of Drug (ID: DMO47TL)

Drug Name

CORT-108297

Synonyms

1018679-79-2; Cort108297; CORT 108297; UNII-A17W0640NB; CHEMBL271220; A17W0640NB; 1H-Pyrazolo[3,4-g]isoquinoline, 4a-(ethoxymethyl)-1-(4-fluorophenyl)-4,4a,5,6,7,8-hexahydro-6-[[4-(trifluoromethyl)phenyl]sulfonyl]-, (4aR)-;1H-Pyrazolo[3,4-g]isoquinoline, 4a-(ethoxymethyl)-1-(4-fluorophenyl)-4,4a,5,6,7,8-hexahydro-6-[[4-(trifluoromethyl)phenyl]sulfonyl]-, (4aR)-; ADS-108297; SCHEMBL755070; DTXSID70144304; MolPort-044-723-886; BCP16798; BDBM50372968; ZINC29128012; AKOS027338706; SB17316; KS-0000064X; AS-35226

Indication

Disease Entry	ICD 11	Status	REF
Weight gain	MG43.6	Discontinued in Phase 1/2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C26H25F4N3O3S
Canonical SMILES: CCOCC12CC3=C(C=C1CCN(C2)S(=O)(=O)C4=CC=C(C=C4)C(F)(F)F)N(N=C3)C5=CC=C(C=C5)F
InChI: 1S/C26H25F4N3O3S/c1-2-36-17-25-14-18-15-31-33(22-7-5-21(27)6-8-22)24(18)13-20(25)11-12-32(16-25)37(34,35)23-9-3-19(4-10-23)26(28,29)30/h3-10,13,15H,2,11-12,14,16-17H2,1H3/t25-/m1/s1
InChIKey: SLKURXRZHJOZOD-RUZDIDTESA-N

Cross-matching ID

PubChem CID: 44454750
CAS Number: 1018679-79-2
TTD ID: D00PDG

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028115)