Details of the Drug

General Information of Drug (ID: DMO5MUY)

Drug Name
NSC-207895
Synonyms
58131-57-0; NSC 207895; NSC207895; NSC 179940; MLS000756495; Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide; 4-(4-Methyl-1-piperazinyl)-7-nitro-benzofurazan 3-oxide; BENZOFURAZAN, 7-(4-METHYL-1-PIPERAZINYL)-4-NITRO-, 1-OXIDE; 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium; SMR000528763; NSC 207895 (XI-006); NSC-207895 (XI-006); 4-(4-methyl-1-piperazinyl)-7-nitro-2,1,3-benzoxadiazole, 3-oxide; XI-006; WLN: T56 BNONJ BO FNW I- AT6N DNTJ D1; 7-(4-Methyl-1-piperazinyl)-4-nitrobenzofurazan 1-oxide; B2368; NCIStruc1_000831; NCIStruc2_001869; cc-262; cid_42640; MLS006011023; SCHEMBL8738959; CHEMBL1608727; BDBM51256; DTXSID50206858; HMS2861M23; XI006; ZINC5180959; NSC179940; s2678; BCP9000997; NCGC00246958-01; NCGC00246958-02; NCGC00246958-03; HY-14714; NCI60_001741; BCP0726000315; NSC-207895?XI-006?; A4209; CS-0003525; NSC-207895 - XI-006; NSC?207895?(XI-006); X7598; Z-3234; 7-(4-methylpiperazino)-4-nitro-1-oxido-benzofurazan-1-ium; 2,1,3-Benzoxadiazole, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide; 2,1,3-benzoxadiazole, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide; 4-(4-methyl-1-piperazinyl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium; 7-(4-methylpiperazin-1-yl)-4-nitrobenzo[c][1,2,5]oxadiazole 1-oxide; 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxidanidyl-2,1,3-benzoxadiazol-3-ium; 4-(hydroxy(oxido)amino)-7-(4-methyl-1-piperazinyl)-2,15,3-benzoxadiazol-1-ol
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Preclinical [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 279.25
Logarithm of the Partition Coefficient (xlogp) 1.2
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C11H13N5O4
IUPAC Name
4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium
Canonical SMILES
CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]
InChI
InChI=1S/C11H13N5O4/c1-13-4-6-14(7-5-13)9-3-2-8(15(17)18)10-11(9)16(19)20-12-10/h2-3H,4-7H2,1H3
InChIKey
MWFZDJLPWDCQIL-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
42640
CAS Number
58131-57-0
TTD ID
DPBE75

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
p53-binding protein Mdm4 (MDM4) TT9OUDQ MDM4_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.8609 4.6567 3.6999 6.8802
A-673 GDSC1 2.3451 3.1471 2.3419 24.7302
CADO-ES1 GDSC1 3.2609 5.173 2.8569 16.0746
SK-PN-DW GDSC1 3.5201 4.6979 3.3216 11.3782
EW-3 GDSC1 3.7333 7.2336 2.3505 17.6309
CHSA0108 GDSC1 3.7712 4.8058 3.5438 8.4755
NOS-1 [Human HNSCC] GDSC1 3.9363 5.5638 3.3563 9.1373
H-EMC-SS GDSC1 3.9559 5.8085 3.2552 9.8385
ES5 GDSC1 3.9741 5.3902 3.4761 8.0475
EW-18 GDSC1 4.0061 5.7375 3.3364 8.997
SK-ES-1 GDSC1 4.1538 6.0719 3.3032 8.6632
ES1 GDSC1 4.2871 5.5888 3.6593 5.3537
EW-7 GDSC1 4.3481 5.7067 3.6512 5.1954
ES7 GDSC1 4.5134 6.6027 3.337 7.0996
TC-71 GDSC1 4.6666 6.2393 3.6331 4.3039
ES6 GDSC1 4.745 7.0779 3.2786 6.8126
ES4 GDSC1 5.0973 9.3517 2.4204 12.153
EW-13 GDSC1 5.2243 7.4108 3.4491 4.2179
EW-1 GDSC1 5.2536 7.3724 3.4856 3.8858
ES8 GDSC1 5.4147 7.3999 3.57 2.9484
EW-24 GDSC1 5.5333 7.2157 3.7163 1.7891
MG-63 GDSC1 5.7945 7.2889 3.8126 0.9234
EW-11 GDSC1 5.7969 8.3881 3.3467 3.7068
SJSA-1 GDSC1 5.8342 7.7469 3.6451 1.7641
CHSA8926 GDSC1 6.3051 8.0296 3.7471 0.7543
CHSA0011 GDSC1 6.4006 10.0118 2.9657 5.0641
HOS GDSC1 6.5599 7.7761 3.9334 0.1203
CAL-72 GDSC1 6.6101 8.3407 3.7547 0.5248
SaOS-2 GDSC1 6.6349 8.1601 3.8285 0.3045
U2OS GDSC1 6.6449 8.9146 3.5528 1.295
CAL-78 GDSC1 6.7447 8.7372 3.6625 0.7577
HuO-3N1 GDSC1 6.9414 9.1904 3.5736 0.953
HuO9 GDSC1 6.9723 9.0133 3.6517 0.6507
MHH-ES-1 GDSC1 7.3197 8.8449 3.8362 0.1148
EW-16 GDSC1 7.353 9.2447 3.7125 0.3137
NY GDSC1 7.3949 9.4328 3.6623 0.4144
G-292 clone A141B1 GDSC1 7.7929 17.5006 0.3523 16.7715
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 144 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 0.0043 1.7597 -0.0029 53.9166
SU-DHL-5 GDSC1 -0.6568 0.4196 -0.6568 62.2216
P32/ISH GDSC1 1.0939 2.1486 1.0927 40.3572
Ku812 GDSC1 1.1036 2.0857 1.1029 40.2335
BV-173 GDSC1 1.197 2.0082 1.1968 39.0627
CTB-1 GDSC1 1.375 2.8977 1.3555 36.9534
Mono-Mac-6 GDSC1 2.149 4.4313 1.9198 28.6259
MY-M12 GDSC1 2.5201 3.724 2.4807 22.7738
ALL-PO GDSC1 2.5674 4.3185 2.4081 22.9729
SU-DHL-16 GDSC1 2.656 3.3508 2.6527 20.8449
NB4 GDSC1 2.6967 4.3408 2.5431 21.3232
OCI-M1 GDSC1 2.7253 4.1971 2.6119 20.6962
NALM-6 GDSC1 2.733 4.4244 2.5588 21.0095
SIG-M5 GDSC1 2.7445 3.7822 2.7121 19.924
SR GDSC1 2.7859 3.7552 2.7596 19.3676
BL-41 GDSC1 2.8216 3.656 2.8073 18.8447
RS4;11 GDSC1 2.8559 3.7422 2.8351 18.4568
BC-1 GDSC1 2.8973 3.8507 2.8659 18.0079
MLMA GDSC1 2.9611 5.3271 2.4787 20.3318
MOLM-13 GDSC1 2.9653 4.4017 2.8189 17.9235
Daudi GDSC1 2.9774 5.0714 2.5987 19.396
YT GDSC1 3.0783 3.9842 3.0398 15.7915
KMS-11 GDSC1 3.1094 4.5295 2.9367 16.3081
SUP-M2 GDSC1 3.1746 6.3205 2.2575 20.827
SUP-HD1 GDSC1 3.1853 5.2279 2.7549 17.1993
NKM-1 GDSC1 3.2031 5.1935 2.7878 16.87
QIMR-WIL GDSC1 3.2436 11.3363 -0.12 32.6009
697 GDSC1 3.2843 4.3735 3.175 13.6909
OCI-Ly19 GDSC1 3.2915 4.914 2.9943 14.9225
LP-1 GDSC1 3.3283 5.2624 2.8892 15.5
CESS GDSC1 3.3387 5.3044 2.8818 15.5024
EoL-1 GDSC1 3.3517 8.6695 1.2946 26.0246
JSC-1 GDSC1 3.3649 4.6566 3.1702 13.2795
ML-2 GDSC1 3.3959 4.352 3.303 12.1865
NOMO-1 GDSC1 3.4066 4.5662 3.2471 12.5135
HC-1 GDSC1 3.448 6.2341 2.5666 17.3144
Karpas-45 GDSC1 3.4525 5.5812 2.8748 15.0014
CA46 GDSC1 3.4589 5.2765 3.0177 13.9069
P12-Ichikawa GDSC1 3.4712 4.644 3.2892 11.8678
LC4-1 GDSC1 3.4936 5.6991 2.862 14.9029
MOLT-13 GDSC1 3.5106 5.071 3.1601 12.5998
HL-60 GDSC1 3.5215 4.2879 3.4574 10.4246
ST486 GDSC1 3.536 5.4359 3.0249 13.4817
ALL-SIL GDSC1 3.5372 5.3098 3.0829 13.0417
A3/Kawakami GDSC1 3.5597 4.7109 3.3589 10.9026
Namalwa GDSC1 3.5939 4.346 3.5207 9.5828
BE-13 GDSC1 3.6016 5.8923 2.8779 14.285
OCI-AML-2 GDSC1 3.6044 4.9308 3.3172 10.9754
Reh GDSC1 3.6702 4.8924 3.402 10.0229
DB GDSC1 3.7057 5.1456 3.3274 10.4037
MOLP-8 GDSC1 3.7085 7.3304 2.2802 18.239
Karpas-422 GDSC1 3.7172 6.7643 2.5663 16.1203
CCRF-CEM GDSC1 3.7178 5.3652 3.2392 11.0121
HEL GDSC1 3.7216 5.7994 3.0382 12.5263
SUP-T1 GDSC1 3.7264 5.3852 3.2384 10.9783
SU-DHL-6 GDSC1 3.8039 4.8307 3.567 8.1412
KE-37 GDSC1 3.81 5.0295 3.4852 8.7218
EB2 GDSC1 3.819 5.1999 3.4161 9.2012
Karpas-620 GDSC1 3.8368 5.2284 3.4204 9.0868
NU-DUL-1 GDSC1 3.84 5.0889 3.4883 8.5567
MHH-PREB-1 GDSC1 3.8402 5.4447 3.3217 9.8256
Jiyoye GDSC1 3.8917 5.4275 3.3796 9.1521
OCI-AML-5 GDSC1 3.9003 4.475 3.8125 5.8647
PF-382 GDSC1 3.9092 5.4369 3.3918 8.9808
OCI-AML-3 GDSC1 3.9135 4.8965 3.6499 6.9923
BALL-1 GDSC1 3.916 5.6617 3.2897 9.7403
RPMI-8402 GDSC1 3.922 5.6957 3.2787 9.7993
SU-DHL-8 GDSC1 3.9279 4.7682 3.7218 6.3847
GDM-1 GDSC1 3.9316 6.8947 2.6974 14.2401
KMOE-2 GDSC1 3.932 6.1314 3.0747 11.3402
Farage GDSC1 3.9752 5.66 3.3458 9.0534
KG-1 GDSC1 3.9771 5.3579 3.4945 7.8917
A4/Fukuda GDSC1 3.9842 5.1909 3.5817 7.1885
KOPN-8 GDSC1 4.0179 5.0448 3.6839 6.2531
KMS-12-BM GDSC1 4.047 6.1523 3.1686 10.1392
MC116 GDSC1 4.0601 4.5056 3.9713 3.8878
Loucy GDSC1 4.0769 6.1109 3.2159 9.6502
P30/OHK GDSC1 4.0848 5.4203 3.5645 6.8918
L-363 GDSC1 4.0956 4.7769 3.8863 4.3535
RPMI-8226 GDSC1 4.1019 5.5076 3.537 7.0363
THP-1 GDSC1 4.132 5.939 3.3502 8.3797
SU-DHL-1 GDSC1 4.1594 4.7339 3.9687 3.4361
HH [Human lymphoma] GDSC1 4.1608 7.0261 2.8334 12.2964
K-562 GDSC1 4.1672 5.3866 3.6557 5.8427
WIL2 NS GDSC1 4.1755 5.0758 3.8169 4.547
MOLT-16 GDSC1 4.1799 5.391 3.6649 5.7201
SUP-B15 GDSC1 4.209 6.0365 3.3688 7.9354
EJM GDSC1 4.2091 5.6087 3.5822 6.2558
Karpas-299 GDSC1 4.2225 5.1387 3.8279 4.2717
RPMI-8866 GDSC1 4.2426 6.0476 3.3922 7.6243
RPMI-6666 GDSC1 4.2551 5.6184 3.6172 5.8045
Ramos.2G6.4C10 GDSC1 4.2574 5.2859 3.7852 4.4726
VAL GDSC1 4.265 5.7385 3.5657 6.1734
GR-ST GDSC1 4.2654 6.6875 3.0917 9.8986
RC-K8 GDSC1 4.3697 5.4178 3.8133 3.8413
Sc-1 GDSC1 4.3744 5.7034 3.6744 4.9195
SU-DHL-10 GDSC1 4.3771 5.3263 3.8649 3.4094
HAL-01 GDSC1 4.3895 7.186 2.9459 10.5822
EM-2 GDSC1 4.4647 5.9089 3.6441 4.8507
VL51 GDSC1 4.4728 6.2816 3.4648 6.2323
Hs 445 GDSC1 4.535 6.4351 3.4373 6.2417
DEL GDSC1 4.6173 5.5302 3.9427 2.0755
ATN-1 GDSC1 4.6301 6.129 3.6606 4.2002
MV4-11 GDSC1 4.6338 6.2303 3.6135 4.554
TUR GDSC1 4.6568 5.907 3.7882 3.1403
WSU-NHL GDSC1 4.7196 6.3475 3.6184 4.263
KY821 GDSC1 4.7227 6.164 3.7098 3.5552
ME1 GDSC1 4.7332 7.5928 3.0154 8.8823
LAMA-84 GDSC1 4.7645 10.4101 1.6384 18.4351
PL-21 GDSC1 4.7709 7.7755 2.9535 9.236
CTV-1 GDSC1 4.7924 6.4437 3.6229 4.0239
JJN-3 GDSC1 4.7948 6.4611 3.6162 4.0682
OPM-2 GDSC1 4.8233 6.8865 3.4297 5.4138
SK-MM-2 GDSC1 4.8303 6.6081 3.5698 4.3239
AMO1 GDSC1 4.8318 6.5699 3.5893 4.172
JVM-3 GDSC1 4.8425 6.5455 3.6084 3.9978
Raji GDSC1 4.847 6.2811 3.7378 3.0159
U266B1 GDSC1 4.8805 7.1576 3.3384 5.9495
HT GDSC1 4.8862 7.0028 3.4176 5.3276
ARH-77 GDSC1 4.9183 8.7352 2.5904 11.4889
SU-DHL-4 GDSC1 4.929 6.2707 3.795 2.4034
BC-3 GDSC1 4.9558 6.5343 3.6889 3.1094
KCL-22 GDSC1 5.0755 7.0338 3.5308 3.9794
DND-41 GDSC1 5.1023 8.6875 2.7504 9.7441
MOLT-4 GDSC1 5.211 8.9325 2.7091 9.728
JVM-2 GDSC1 5.2219 7.4925 3.4092 4.5144
L-1236 GDSC1 5.262 7.746 3.3157 5.102
JURL-MK1 GDSC1 5.2639 7.4996 3.4327 4.2433
MN-60 GDSC1 5.3098 7.7555 3.342 4.7928
TK [Human B-cell lymphoma] GDSC1 5.4111 6.7995 3.83 1.2966
U-698-M GDSC1 5.4524 7.7877 3.416 3.9369
P31/FUJ GDSC1 5.6391 7.4319 3.679 1.851
MEG-01 GDSC1 5.7514 8.8079 3.1287 5.2997
RL GDSC1 5.8184 10.2416 2.4972 9.5648
KM-H2 GDSC1 5.8729 8.092 3.5186 2.4607
L-428 GDSC1 5.9064 8.0071 3.5722 2.0849
H9 GDSC1 6.0045 8.9148 3.2299 4.0857
WSU-DLCL2 GDSC1 6.0123 6.8912 4.0418 0.0725
L-540 GDSC1 6.3483 9.8908 2.9899 5.0063
SCC-3 GDSC1 6.3874 7.6453 3.9174 0.1914
Granta-519 GDSC1 6.4316 8.1372 3.7587 0.6203
DG-75 GDSC1 6.7076 8.4639 3.7479 0.4928
HDLM-2 GDSC1 7.1632 9.0134 3.724 0.3544
ROS-50 GDSC1 7.8853 9.5693 3.787 0.0912
⏷ Show the Full List of 144 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC1 3.3762 4.6251 3.1936 13.0539
KYAE-1 GDSC1 3.4435 4.4554 3.3238 11.7773
OACM5.1 C GDSC1 3.5441 4.8169 3.3007 11.4029
OACP4 C GDSC1 3.6678 4.7414 3.4618 9.5988
ESO-26 GDSC1 3.7322 4.3739 3.6634 7.8272
KYSE-50 GDSC1 3.7915 4.4612 3.6998 7.2467
KYSE-220 GDSC1 3.8953 4.6629 3.7333 6.4614
SK-GT-4 GDSC1 4.3133 5.5191 3.7161 4.8091
ESO-51 GDSC1 4.7268 6.949 3.3286 6.4811
TE-12 GDSC1 5.2192 7.5874 3.3627 4.8623
HCE-4 GDSC1 6.3444 8.031 3.7628 0.6649
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 3.2221 4.2998 3.1276 14.3667
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-7 GDSC1 -1.0506 -0.3552 -1.0506 67.1561
SK-N-MC-IXC GDSC1 1.8454 2.3439 1.8454 30.957
KP-N-YN GDSC1 2.421 4.5731 2.1737 25.3807
SJNB-13 GDSC1 2.7163 3.7633 2.6846 20.2717
SJNB-17 GDSC1 3.0063 8.1524 1.2239 28.0154
CHP-134 GDSC1 3.4148 4.9348 3.1165 13.4026
TGW GDSC1 3.4643 13.0776 -0.7897 33.7677
Kelly GDSC1 3.4833 4.3614 3.3957 11.0604
IMR-5 GDSC1 3.6239 4.5082 3.5022 9.5433
SJNB-6 GDSC1 3.6481 5.9121 2.9135 13.8055
SJNB-12 GDSC1 3.8081 5.038 3.4795 8.774
NB1 GDSC1 3.9024 5.2139 3.4915 8.2455
KP-N-YS GDSC1 3.9185 6.4477 2.9066 12.695
NB69 GDSC1 4.0725 5.6338 3.4481 7.8515
GOTO GDSC1 4.0758 5.866 3.3363 8.7128
SK-N-SH GDSC1 4.185 5.1844 3.7718 4.8616
SK-N-BE(2)-M17 GDSC1 4.2564 5.9267 3.4643 7.0051
CHP-126 GDSC1 4.4497 5.7987 3.6871 4.5627
SiMa GDSC1 4.521 6.6885 3.3002 7.3629
GI-ME-N GDSC1 4.5958 6.2306 3.5851 4.8917
NH-12 GDSC1 4.87 9.3749 2.2364 14.1742
CHP-212 GDSC1 5.3121 7.2256 3.5887 3.0284
SK-N-FI GDSC1 5.4471 7.527 3.5316 3.1459
MHH-NB-11 GDSC1 5.4533 7.3966 3.5936 2.714
SK-N-DZ GDSC1 5.7713 7.643 3.6571 1.784
NB(TU)1 GDSC1 5.9189 14.3375 0.5748 20.4874
SJNB-10 GDSC1 6.1856 7.9319 3.7338 0.9093
LA-N-6 GDSC1 6.2727 7.7917 3.8225 0.4994
SJNB-14 GDSC1 6.3644 7.988 3.7868 0.5646
SJNB-5 GDSC1 6.7721 8.0932 3.9001 0.1266
SK-N-AS GDSC1 8.0045 22.438 -1.8807 24.2692
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 2.4369 3.5431 2.4136 23.7098
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Evsa-T GDSC1 2.9752 4.4177 2.825 17.8265
CAL-85-1 GDSC1 3.0014 5.1442 2.5953 19.2941
MRK-nu-1 GDSC1 3.0797 4.9632 2.7497 17.7838
OCUB-M GDSC1 3.0966 4.8783 2.8002 17.3354
ZR-75-30 GDSC1 3.3469 4.5451 3.1895 13.2422
BT-483 GDSC1 3.3743 5.4184 2.8685 15.4251
CAL-120 GDSC1 3.7455 5.5656 3.1724 11.3932
MDA-MB-468 GDSC1 3.7881 5.0848 3.4382 9.1794
T-47D GDSC1 4.1068 5.1039 3.7398 5.4347
EFM-19 GDSC1 4.1337 5.205 3.7152 5.5137
COLO 824 GDSC1 4.1758 5.4639 3.6251 6.0489
UACC-812 GDSC1 4.1989 5.1673 3.7928 4.6411
AU565 GDSC1 4.2881 6.2371 3.336 7.8972
HCC70 GDSC1 4.3442 5.3394 3.8317 3.7864
HCC1187 GDSC1 4.4432 6.1446 3.5095 5.9811
CAMA-1 GDSC1 4.4488 6.0547 3.5589 5.574
HCC38 GDSC1 4.4548 6.1708 3.5058 5.9711
HCC1599 GDSC1 4.473 6.0707 3.57 5.4049
HCC202 GDSC1 4.6486 6.385 3.5483 5.015
HDQ-P1 GDSC1 4.7595 7.1411 3.2583 6.9251
JIMT-1 GDSC1 4.767 6.0774 3.7817 2.8929
BT-20 GDSC1 4.7682 6.3456 3.6535 3.8578
MDA-MB-436 GDSC1 4.8284 7.0622 3.3475 6.0302
HCC1806 GDSC1 4.9319 7.1675 3.3698 5.5639
HCC1500 GDSC1 5.0569 7.5477 3.2728 5.9542
HCC1569 GDSC1 5.1376 7.5348 3.3339 5.2819
BT-474 GDSC1 5.1568 6.7109 3.7306 2.3685
MDA-MB-453 GDSC1 5.2768 7.3068 3.5303 3.5139
MDA-MB-175-VII GDSC1 5.3217 7.8213 3.3188 4.9336
CAL-51 GDSC1 5.3336 6.9897 3.7069 2.1868
EFM-192A GDSC1 5.4027 7.3379 3.591 2.8299
BT-549 GDSC1 5.4309 8.5146 3.0621 6.5373
DU4475 GDSC1 5.47 6.6522 3.918 0.7525
MDA-MB-330 GDSC1 5.4782 7.8379 3.4086 3.9336
MDA-MB-361 GDSC1 5.6448 7.7826 3.53 2.7785
HCC2218 GDSC1 5.7361 8.6168 3.2073 4.7847
MFM-223 GDSC1 5.7729 7.3624 3.7734 1.1416
HCC2157 GDSC1 5.8304 7.1772 3.8715 0.6275
CAL-148 GDSC1 5.9386 7.4247 3.8228 0.741
UACC-893 GDSC1 5.964 8.2709 3.4897 2.4924
YMB-1-E GDSC1 6.036 8.0452 3.6205 1.6312
HCC1419 GDSC1 6.0413 8.0371 3.6264 1.593
MDA-MB-415 GDSC1 6.2584 8.2702 3.6337 1.3031
HCC1395 GDSC1 6.2926 7.9362 3.777 0.6481
MDA-MB-231 GDSC1 6.3475 11.6901 2.1583 10.483
MDA-MB-157 GDSC1 6.433 8.1769 3.7445 0.6708
HCC1428 GDSC1 6.4817 8.0467 3.8112 0.4192
MCF-7 GDSC1 6.7225 8.3423 3.7969 0.3483
Hs 578T GDSC1 7.0727 8.7756 3.7736 0.2746
HCC1954 GDSC1 7.1155 9.0498 3.6935 0.4512
HCC1937 GDSC1 7.1554 8.969 3.7366 0.3279
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF268 GDSC1 0.5913 1.4904 0.5912 46.6335
KNS-81-FD GDSC1 1.9605 2.7578 1.9594 29.5248
D-423MG GDSC1 2.4328 3.6179 2.4013 23.814
AM-38 GDSC1 3.0166 6.756 1.8986 24.0193
D-566MG GDSC1 3.3557 4.2384 3.2891 12.5112
GB-1 GDSC1 3.3792 5.4794 2.8465 15.5639
SK-MG-1 GDSC1 3.5922 6.0208 2.8077 14.8574
GI-1 GDSC1 3.5965 4.433 3.4973 9.7284
KALS-1 GDSC1 3.8569 5.2859 3.4132 9.0502
MOG-G-UVW GDSC1 3.9867 4.9625 3.6923 6.3295
DK-MG GDSC1 4.0637 4.6959 3.8921 4.4578
KNS-42 GDSC1 4.0665 4.6156 3.931 4.1534
MOG-G-CCM GDSC1 4.1456 5.9875 3.338 8.4225
SF539 GDSC1 4.3067 5.9402 3.5001 6.537
YKG-1 GDSC1 4.3584 6.331 3.3476 7.5516
D-336MG GDSC1 4.3761 6.5445 3.2555 8.2131
NMC-G1 GDSC1 4.3946 7.0491 3.0184 10.0014
KINGS-1 GDSC1 4.412 5.6623 3.7252 4.3898
Daoy GDSC1 4.4654 5.55 3.823 3.4447
GaMG GDSC1 4.8608 6.3651 3.707 3.2098
KS-1 [Human Krukenberg tumour] GDSC1 4.9499 7.7421 3.1028 7.5476
U-251MG GDSC1 4.9759 6.2912 3.8142 2.1643
SF295 GDSC1 5.0013 7.6747 3.1724 6.8692
Onda 11 GDSC1 5.0292 7.0297 3.5024 4.3053
PFSK-1 GDSC1 5.1609 7.3941 3.4162 4.613
H4 GDSC1 5.1707 7.0926 3.5639 3.5127
LN-405 GDSC1 5.2551 6.8041 3.7452 2.0795
Becker GDSC1 5.4087 7.3027 3.6102 2.6888
A-172 GDSC1 5.454 7.3759 3.6033 2.6484
8-MG-BA GDSC1 5.5676 7.8036 3.4769 3.2776
LN-18 GDSC1 5.6038 6.5354 4.0179 0.2517
T98G GDSC1 5.6106 8.4672 3.1995 5.1164
DBTRG-05MG GDSC1 5.6242 7.4788 3.6512 2.0437
U-87MG ATCC GDSC1 5.6447 7.0792 3.8277 1.0108
Onda 10 GDSC1 5.7799 7.9823 3.5165 2.6283
Hs 683 GDSC1 5.8109 7.4366 3.7612 1.1604
D-502MG GDSC1 5.8152 7.8979 3.5716 2.228
D-542MG GDSC1 5.9139 7.5626 3.7582 1.0616
LN-229 GDSC1 5.9175 7.9568 3.599 1.912
M059J GDSC1 5.9795 7.7942 3.6958 1.3017
SF126 GDSC1 5.9992 7.3865 3.8625 0.5353
CAS-1 GDSC1 6.0366 7.2014 3.9441 0.256
D283 Med GDSC1 6.1881 7.4548 3.9111 0.2776
D-263MG GDSC1 6.2467 7.8628 3.7857 0.6479
D-247MG GDSC1 6.3225 12.5624 1.7261 13.2261
LNZTA3WT4 GDSC1 6.4216 8.1969 3.7324 0.7244
SW1088 GDSC1 6.4231 8.0039 3.8041 0.4722
SW1783 GDSC1 6.4438 8.608 3.5837 1.3507
YH-13 GDSC1 6.4928 8.0908 3.7997 0.4482
U-118MG GDSC1 6.4943 7.856 3.8831 0.2293
ONS-76 GDSC1 6.603 8.644 3.6391 0.9556
42-MG-BA GDSC1 6.7466 8.0334 3.9114 0.1156
D-392MG GDSC1 6.7923 8.9405 3.6059 0.9395
SNB-75 GDSC1 7.1151 8.9834 3.7168 0.3906
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 2.6731 3.7926 2.6345 20.8558
ETK-1 GDSC1 3.631 4.7506 3.4192 10.0964
TGBC24TKB GDSC1 5.6023 7.5359 3.6148 2.3073
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1 1.8661 2.6152 1.8656 30.7006
KLE GDSC1 2.1538 3.8078 2.0738 27.6109
MFE-296 GDSC1 3.4654 4.3656 3.3749 11.3034
RL95-2 GDSC1 3.6247 4.3368 3.5569 9.1617
AN3-CA GDSC1 3.8361 4.5567 3.7131 6.9131
EN GDSC1 3.9147 4.3366 3.8734 5.3622
MFE-280 GDSC1 4.6627 6.5279 3.4885 5.4364
MFE-319 GDSC1 6.8692 8.17 3.9076 0.0995
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RXF 393L GDSC1 1.7747 4.239 1.5643 33.1092
KTCTL-140 GDSC1 2.8154 3.7821 2.7876 19.0078
KTCTL-195 GDSC1 3.1442 4.2526 3.0548 15.305
786-O GDSC1 3.4377 4.1845 3.3907 11.3562
KTCTL-21 GDSC1 3.5342 4.4607 3.4207 10.6038
769-P GDSC1 3.7286 4.4977 3.6191 8.1545
VMRC-RCZ GDSC1 3.8294 4.5584 3.7054 7.0033
BB65-RCC GDSC1 3.9088 4.7665 3.703 6.6177
KMRC-1 GDSC1 4.1669 4.7659 3.9604 3.4671
KMRC-20 GDSC1 4.2153 4.9405 3.9198 3.5799
NCC021 GDSC1 4.3757 5.7923 3.631 5.2574
KTCTL-1M GDSC1 4.4684 6.5537 3.3257 7.3403
OS-RC-2 GDSC1 4.5923 5.798 3.7953 3.2711
ACHN GDSC1 4.6549 6.0919 3.6968 3.847
LB1047-RCC GDSC1 4.7665 7.2495 3.2101 7.2766
RCC10RGB GDSC1 5.1737 7.7947 3.2339 5.9335
LB2241-RCC GDSC1 5.2271 7.1672 3.5642 3.383
A-498 GDSC1 5.4747 7.1824 3.6997 1.9865
VMRC-RCW GDSC1 5.5138 7.5934 3.5403 2.9552
KTCTL-13 GDSC1 5.8113 7.9808 3.5339 2.4662
CAL-54 GDSC1 5.9222 10.1431 2.6125 8.5065
SW13 GDSC1 5.9692 7.715 3.7227 1.1767
Caki-1 GDSC1 6.0283 8.0673 3.6077 1.7116
SW156 GDSC1 6.1505 8.1092 3.6485 1.3475
SN12C GDSC1 6.1944 7.8607 3.7648 0.7703
BFTC-909 GDSC1 6.3735 7.8247 3.8495 0.3616
UO-31 GDSC1 6.4718 8.7817 3.5273 1.598
TK-10 GDSC1 6.5608 9.728 3.1778 3.4433
KTCTL-26A GDSC1 6.7995 8.4709 3.7801 0.3593
LB996-RCC GDSC1 6.9316 8.8764 3.6855 0.5653
HA7-RCC GDSC1 7.0628 9.3983 3.5456 0.9712
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDST8 GDSC1 2.7317 3.7941 2.6969 20.0995
SNU-61 GDSC1 2.9098 4.1233 2.8301 18.1678
SNU-1040 GDSC1 3.1288 4.3997 2.9978 15.779
LS411N GDSC1 3.6427 5.8398 2.9427 13.608
C2BBe1 GDSC1 3.7398 5.8851 3.0146 12.6258
SNU-C5 GDSC1 3.8009 4.4526 3.713 7.103
SNU-175 GDSC1 3.8286 4.5561 3.7054 7.0076
T84 GDSC1 3.8609 4.8605 3.6126 7.5239
LS180 GDSC1 3.9189 4.7149 3.7359 6.3244
SW837 GDSC1 3.9937 4.7894 3.7792 5.6389
LS1034 GDSC1 4.0759 4.7698 3.8703 4.5656
CCK-81 GDSC1 4.2191 5.8383 3.4764 7.0498
HCT 15 GDSC1 4.3182 5.412 3.7738 4.3368
LS123 GDSC1 4.4286 5.5036 3.8175 3.6082
RKO GDSC1 4.4288 6.048 3.5463 5.7411
SW1116 GDSC1 4.4344 5.9869 3.5812 5.4469
NCI-H747 GDSC1 4.4346 5.9948 3.5775 5.4758
SW626 GDSC1 4.579 6.4445 3.4666 5.8699
COLO205 GDSC1 4.7394 6.0032 3.7986 2.8375
SW48 GDSC1 4.85 7.5729 3.1128 7.7697
SW620 GDSC1 4.8503 6.3089 3.7267 3.09
HT-29 GDSC1 4.8899 6.2261 3.7913 2.5194
KM12 GDSC1 4.9204 6.7342 3.5707 4.0751
GP5d GDSC1 4.9943 6.4549 3.7501 2.5777
LS513 GDSC1 5.2653 7.4407 3.4611 4.0355
CW-2 GDSC1 5.2707 8.2255 3.093 6.7252
HCT 116 GDSC1 5.2817 6.9465 3.6969 2.3506
SNU-C2B GDSC1 5.3588 7.5827 3.4532 3.8795
HCC2998 GDSC1 5.4081 7.8341 3.3674 4.3806
SW948 GDSC1 5.4308 7.1317 3.6981 2.0712
CaR-1 GDSC1 5.5611 7.6958 3.5215 2.9902
SNU-407 GDSC1 5.5653 7.575 3.5775 2.6128
NCI-H716 GDSC1 5.5692 8.0836 3.3509 4.1416
COLO 320HSR GDSC1 5.6998 7.505 3.6791 1.7596
SNU-81 GDSC1 5.9134 13.7644 0.8524 19.1613
SW1417 GDSC1 5.9889 8.0841 3.5814 1.9126
RCM-1 [Human ESC] GDSC1 6.0907 7.3632 3.907 0.3336
COLO 678 GDSC1 6.2407 8.2813 3.6211 1.3846
HT-55 GDSC1 6.2923 7.6157 3.8931 0.2804
CL-11 GDSC1 6.3235 8.7623 3.4647 2.1142
HT115 GDSC1 6.4618 7.7276 3.9156 0.1734
SNU-C1 GDSC1 6.4926 8.1397 3.7819 0.5041
SW1463 GDSC1 6.8717 8.4071 3.8285 0.2244
LoVo GDSC1 6.9106 8.9814 3.6389 0.7322
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 1.6324 4.6029 1.3055 35.4562
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLE GDSC1 0.7437 2.1284 0.7394 44.7478
JHH-2 GDSC1 0.9299 1.6125 0.9299 42.4001
SNU-423 GDSC1 0.99 1.901 0.9897 41.6508
SNU-398 GDSC1 1.0882 2.379 1.0834 40.4493
SK-HEP-1 GDSC1 2.5523 3.4792 2.5398 22.1989
JHH-6 GDSC1 3.0079 10.1806 0.2365 32.3676
JHH-1 GDSC1 3.1853 3.7523 3.1791 14.2467
SNU-387 GDSC1 3.6674 4.8338 3.4236 9.8788
SNU-475 GDSC1 3.9712 4.9466 3.6845 6.4605
Huh-7 GDSC1 4.0123 4.6761 3.8488 5.0289
JHH-4 GDSC1 4.6862 7.3337 3.1078 8.3201
Hep 3B2.1-7 GDSC1 4.9702 6.8614 3.5434 4.1506
SNU-449 GDSC1 5.2634 7.3069 3.522 3.6027
JHH-7 GDSC1 5.2638 7.0336 3.6474 2.7226
Hep-G2/C3A GDSC1 6.2034 7.3406 3.9564 0.1684
HuH-1 GDSC1 6.4629 8.0329 3.809 0.4356
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H64 GDSC1 1.027 2.0602 1.0262 41.1914
COR-L321 GDSC1 1.1166 2.2247 1.1148 40.0773
NCI-H82 GDSC1 1.2294 2.435 1.2255 38.6807
Lu-135 GDSC1 1.5145 2.7086 1.5083 35.1313
NCI-H2135 GDSC1 1.6477 2.9231 1.6363 33.4988
NCI-H847 GDSC1 1.8124 2.3425 1.8124 31.3688
SBC-1 GDSC1 2.0454 3.3469 2.0205 28.6136
COR-L303 GDSC1 2.3968 3.5609 2.3695 24.2366
IST-SL1 GDSC1 2.4594 5.2053 1.9946 26.3409
NCI-H211 GDSC1 2.6114 4.3511 2.4471 22.4583
NCI-H2227 GDSC1 2.6217 3.7493 2.5856 21.4827
CPC-N GDSC1 2.653 3.5547 2.6391 20.9492
NCI-H510A GDSC1 2.6864 4.5496 2.47 21.8772
SBC-3 GDSC1 2.715 3.6432 2.6966 20.2029
NCI-H748 GDSC1 2.7531 4.4193 2.5823 20.736
Lu-139 GDSC1 2.8902 3.7985 2.8651 18.0556
EPLC-272H GDSC1 2.899 7.7148 1.3311 27.9724
DMS 273 GDSC1 2.9586 3.8071 2.9366 17.1809
COR-L88 GDSC1 3.0533 4.3476 2.9303 16.6669
SBC-5 GDSC1 3.0764 3.8224 3.0594 15.6767
NCI-H2171 GDSC1 3.0808 4.304 2.9723 16.2247
EMC-BAC-2 GDSC1 3.1229 4.4704 2.9701 16.0021
HCC78 GDSC1 3.1383 4.0691 3.0894 15.1101
NCI-H187 GDSC1 3.1725 4.1214 3.1161 14.732
LCLC-97TM1 GDSC1 3.1747 4.9639 2.8506 16.5636
NCI-H1436 GDSC1 3.1933 5.1827 2.782 16.9617
NCI-H2110 GDSC1 3.1942 5.1237 2.8072 16.7754
NCI-H2595 GDSC1 3.2897 4.5151 3.1373 13.9204
NCI-H2196 GDSC1 3.3202 4.4067 3.2044 13.2878
HCC33 GDSC1 3.3834 4.3962 3.2765 12.4385
NCI-H841 GDSC1 3.41 4.2067 3.3557 11.7515
NCI-H446 GDSC1 3.4677 5.0108 3.1408 12.9564
NCI-H292 GDSC1 3.5294 4.9066 3.2487 11.8557
ABC-1 GDSC1 3.5794 4.7009 3.3838 10.6201
NCI-H661 GDSC1 3.587 4.5438 3.45 10.1102
NCI-H1694 GDSC1 3.6275 4.9487 3.3337 10.7389
NCI-H1092 GDSC1 3.6397 4.4678 3.533 9.2416
NCI-H1048 GDSC1 3.7065 4.3664 3.6376 8.1483
SW1271 GDSC1 3.7066 4.9914 3.3969 9.8806
CAL-12T GDSC1 3.7158 5.3529 3.2429 10.9929
COR-L95 GDSC1 3.7569 5.1866 3.3604 9.913
Lu-134-A GDSC1 3.7881 5.4819 3.2535 10.5817
A-427 GDSC1 3.7995 4.9161 3.5253 8.4725
NCI-H345 GDSC1 3.8471 4.7803 3.6335 7.4365
NCI-H1944 GDSC1 3.9539 7.433 2.45 15.9937
NCI-H2342 GDSC1 3.9779 5.4015 3.4742 8.0455
NCI-H2009 GDSC1 4.0076 4.9787 3.7053 6.1355
LB647-SCLC GDSC1 4.1235 6.3911 3.1177 10.2349
NCI-H2085 GDSC1 4.1558 5.7829 3.4488 7.5119
NCI-H1963 GDSC1 4.168 5.6526 3.5243 6.8711
NCI-H2141 GDSC1 4.2187 5.2073 3.7905 4.5802
NCI-H2081 GDSC1 4.2328 5.6994 3.5575 6.3593
Ms-1 GDSC1 4.2569 5.6398 3.6081 5.8698
Lu-165 GDSC1 4.262 5.4342 3.7151 5.0072
NCI-H358 GDSC1 4.265 5.6874 3.5912 5.9727
NCI-H2373 GDSC1 4.2865 5.3719 3.7671 4.5056
NCI-H1703 GDSC1 4.3041 5.3178 3.809 4.1101
RERF-LC-MS GDSC1 4.3248 5.2761 3.8472 3.7338
PaCa-3 GDSC1 4.3547 7.2371 2.8916 11.1266
NCI-H2795 GDSC1 4.3624 7.9426 2.5452 13.7208
HCC44 GDSC1 4.3711 7.3932 2.8271 11.5633
NCI-H1781 GDSC1 4.3832 5.6275 3.7195 4.5337
NCI-H810 GDSC1 4.3985 5.8578 3.6168 5.2897
SHP-77 GDSC1 4.4026 5.3781 3.8595 3.3656
DMS 79 GDSC1 4.4131 6.0476 3.5338 5.8933
PC-14 GDSC1 4.4472 6.2577 3.4564 6.3854
EMC-BAC-1 GDSC1 4.4736 6.6538 3.2799 7.6819
NCI-H650 GDSC1 4.5069 5.9809 3.6411 4.736
NCI-H1437 GDSC1 4.5474 6.1751 3.5759 5.1161
LC-2/ad GDSC1 4.5905 6.2594 3.5669 5.0495
HOP-62 GDSC1 4.6909 6.7664 3.3919 6.1003
NCI-H23 GDSC1 4.713 6.6933 3.4443 5.6271
NCI-H1975 GDSC1 4.7356 8.4202 2.6065 11.9646
COR-L105 GDSC1 4.7606 7.0435 3.3072 6.5437
NCI-H1581 GDSC1 4.7726 6.4319 3.6148 4.1406
Calu-6 GDSC1 4.7774 6.1832 3.738 3.1936
NCI-H526 GDSC1 4.8273 6.4713 3.6337 3.8478
NCI-H2731 GDSC1 4.8421 12.8826 0.467 24.3165
NCI-H2087 GDSC1 4.8575 6.6838 3.552 4.3841
NCI-H1648 GDSC1 4.8714 7.4252 3.201 7.0294
NCI-H1876 GDSC1 4.8988 7.0538 3.4018 5.4133
NCI-H647 GDSC1 4.9105 8.8963 2.5048 12.1373
NCI-H2869 GDSC1 4.9462 6.8833 3.5168 4.4128
NCI-H520 GDSC1 5.0145 6.9597 3.5259 4.1675
NCI-H1688 GDSC1 5.109 7.0492 3.5452 3.7926
NCI-H1623 GDSC1 5.1124 8.8865 2.6602 10.377
NCI-H1869 GDSC1 5.1188 6.9943 3.5771 3.5374
UMC-11 GDSC1 5.1226 7.9177 3.1397 6.7767
EBC-1 GDSC1 5.1325 7.3569 3.4151 4.6916
NCI-H1155 GDSC1 5.157 6.5917 3.7842 2.0043
NCI-H2347 GDSC1 5.1643 8.4679 2.9021 8.4376
NCI-H2591 GDSC1 5.1754 8.1548 3.0617 7.2154
COR-L23 GDSC1 5.2301 7.5249 3.3993 4.5673
NCI-H838 GDSC1 5.2301 8.0415 3.1537 6.3819
BEN GDSC1 5.2489 7.2957 3.5182 3.6624
NCI-H2804 GDSC1 5.2701 8.2143 3.098 6.6897
NCI-H1573 GDSC1 5.3183 8.0926 3.1883 5.8978
NCI-H1915 GDSC1 5.3211 7.3261 3.5483 3.2913
NCI-H2722 GDSC1 5.3221 7.8972 3.2833 5.1913
NCI-H1563 GDSC1 5.3609 7.4955 3.4947 3.582
Lu-65 GDSC1 5.3984 7.6088 3.4654 3.7068
NCI-H720 GDSC1 5.4007 7.6943 3.4275 3.9693
NCI-H2030 GDSC1 5.4244 10.1531 2.2663 12.2403
NCI-H2029 GDSC1 5.4469 7.6397 3.4803 3.4995
HCC15 GDSC1 5.4588 8.0506 3.2984 4.7582
NCI-H1651 GDSC1 5.4727 7.6152 3.5067 3.2642
NCI-H2172 GDSC1 5.4868 7.2232 3.6885 2.0371
HOP-92 GDSC1 5.4888 8.2365 3.2306 5.1751
DMS 114 GDSC1 5.5552 7.4154 3.6418 2.2161
NCI-H3122 GDSC1 5.5586 7.5879 3.568 2.6871
SK-LU-1 GDSC1 5.6224 7.8283 3.4972 3.0359
NCI-H1793 GDSC1 5.6491 8.0743 3.4024 3.6219
SK-MES-1 GDSC1 5.6833 8.1121 3.4051 3.5355
NCI-H2369 GDSC1 5.7082 7.6133 3.6375 1.995
Lu-99A GDSC1 5.7126 8.0502 3.4495 3.1828
NCI-H1568 GDSC1 5.7292 7.7044 3.6095 2.1322
RERF-LC-KJ GDSC1 5.7421 7.2975 3.7852 1.1167
NCI-H322M GDSC1 5.8143 9.1015 3.0318 5.8376
NCI-H2444 GDSC1 5.8245 7.0802 3.9056 0.4976
LK-2 GDSC1 5.8307 8.3528 3.3817 3.41
LCLC-103H GDSC1 5.8312 7.939 3.5624 2.259
NCI-H1693 GDSC1 5.8344 8.1548 3.4708 2.8252
RERF-LC-Sq1 GDSC1 5.8638 8.39 3.3837 3.3359
NCI-H2461 GDSC1 5.8685 8.869 3.1714 4.7521
LOU-NH91 GDSC1 5.8749 7.9464 3.5818 2.075
NCI-H2122 GDSC1 5.9092 7.4286 3.8086 0.8295
NCI-H460 GDSC1 5.9568 7.0029 3.9843 0.189
NCI-H727 GDSC1 5.9731 8.5054 3.3932 3.0799
NCI-H226 GDSC1 6.0292 7.4087 3.8664 0.5009
IA-LM GDSC1 6.0643 8.0022 3.6514 1.4319
NCI-H1734 GDSC1 6.0651 7.9792 3.6611 1.3809
NCI-H524 GDSC1 6.0665 8.2527 3.5496 1.9859
NCI-H69 GDSC1 6.1014 8.9152 3.2839 3.5539
NCI-H596 GDSC1 6.1264 7.5564 3.8508 0.4932
NCI-H1993 GDSC1 6.1412 7.8928 3.7297 0.9686
LXF 289 GDSC1 6.1619 8.1577 3.6343 1.4066
NCI-H1435 GDSC1 6.1873 7.778 3.7931 0.6632
NCI-H209 GDSC1 6.2151 8.388 3.5661 1.6996
NCI-H1770 GDSC1 6.2556 7.9951 3.7395 0.8249
NCI-H2170 GDSC1 6.3 8.3375 3.6258 1.2975
COLO 668 GDSC1 6.3655 8.2636 3.6835 0.969
NCI-H1755 GDSC1 6.3824 8.1335 3.74 0.7238
NCI-H1355 GDSC1 6.4053 8.2469 3.7068 0.8379
NCI-H1304 GDSC1 6.4062 8.1134 3.7572 0.6425
HCC827 GDSC1 6.4371 8.1198 3.7673 0.5863
NCI-H1836 GDSC1 6.4464 8.0854 3.7836 0.5252
A-549 GDSC1 6.4623 8.5329 3.6213 1.1565
NCI-H196 GDSC1 6.4657 7.9806 3.8288 0.3763
NCI-H2228 GDSC1 6.5083 8.719 3.5688 1.3554
NCI-H2803 GDSC1 6.5316 8.0633 3.8242 0.3586
LC-1/sq GDSC1 6.5323 9.1879 3.3909 2.2466
NCI-H2818 GDSC1 6.5392 8.3735 3.7145 0.7082
NCI-H3255 GDSC1 6.5546 8.3701 3.722 0.6704
NCI-H1299 GDSC1 6.5795 8.7349 3.594 1.1697
HARA [Human squamous cell lung carcinoma] GDSC1 6.6058 8.3946 3.7334 0.5975
DMS 53 GDSC1 6.7624 8.5176 3.7496 0.4598
NCI-H2023 GDSC1 6.7888 8.3408 3.8217 0.2646
NCI-H522 GDSC1 6.7975 8.6641 3.7104 0.5609
NCI-H1838 GDSC1 6.8486 8.4896 3.7917 0.3116
NCI-H1650 GDSC1 6.8573 8.375 3.8344 0.217
Calu-3 GDSC1 6.8928 8.7892 3.702 0.5351
IST-SL2 GDSC1 6.9523 8.9488 3.6673 0.6115
NCI-H1792 GDSC1 7.0706 8.8254 3.7557 0.3145
NCI-H441 GDSC1 7.1217 9.2417 3.627 0.6448
NCI-H1666 GDSC1 7.1816 9.0021 3.7346 0.3232
NCI-H2405 GDSC1 7.2012 9.1004 3.7075 0.3796
NCI-H513 GDSC1 7.3673 8.9738 3.8095 0.1408
NCI-H2291 GDSC1 7.4469 9.4237 3.6845 0.3434
SW1573 GDSC1 7.4637 9.6539 3.6099 0.5216
EKVX GDSC1 7.4904 9.6605 3.6176 0.4892
ChaGo-K-1 GDSC1 7.5188 9.3666 3.7297 0.2322
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 3.6544 5.201 3.2506 11.2244
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-410 GDSC1 3.7095 5.3419 3.2416 11.0322
KYSE-180 GDSC1 3.8093 5.5706 3.2319 10.6519
T.T GDSC1 3.8233 4.41 3.7513 6.713
KYSE-270 GDSC1 3.8842 4.6648 3.7209 6.6083
KYSE-150 GDSC1 4.279 5.6255 3.634 5.5828
KYSE-450 GDSC1 4.2904 5.7361 3.5884 5.8999
KYSE-520 GDSC1 4.3145 6.8744 3.0394 10.1263
TE-15 GDSC1 4.4693 6.2314 3.487 6.0694
TE-6 GDSC1 4.5274 6.459 3.4194 6.4068
TE-10 GDSC1 4.8172 6.334 3.6927 3.4295
COLO 680N GDSC1 5.7034 7.9063 3.5079 2.8166
KYSE-510 GDSC1 5.8582 7.458 3.7744 1.0413
OE19 GDSC1 5.9757 7.2068 3.9191 0.3566
TE-9 GDSC1 6.0151 7.47 3.8378 0.6181
OE33 GDSC1 6.2874 9.9518 2.9273 5.5399
TE-5 GDSC1 6.324 7.9487 3.7851 0.5968
OE21 GDSC1 6.3325 8.2377 3.6793 1.017
TE-11 GDSC1 6.6476 8.3653 3.7604 0.4865
KYSE-70 GDSC1 6.666 8.2021 3.8252 0.3004
TE-4 GDSC1 6.6766 8.4307 3.7479 0.5093
TE-8 GDSC1 6.7781 9.3365 3.4462 1.6648
EC-GI-10 GDSC1 6.7789 8.3388 3.8188 0.2744
TE-1 GDSC1 6.8367 8.5191 3.7769 0.3521
KYSE-140 GDSC1 7.0586 9.1414 3.6388 0.6427
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHOS-2 GDSC1 -0.5663 0.4849 -0.5663 61.0939
OC 314 GDSC1 2.4414 4.2626 2.2856 24.5195
OVKATE GDSC1 3.5369 4.7575 3.3166 11.3257
OV56 GDSC1 3.9293 4.3998 3.8699 5.3051
OAW42 GDSC1 4.1624 4.8889 3.8965 3.9812
TOV-112D GDSC1 4.1723 5.188 3.7587 5.0152
FU-OV-1 GDSC1 4.189 5.2344 3.7507 5.011
Caov-3 GDSC1 4.2222 5.0287 3.8824 3.8454
A2780 GDSC1 4.3528 5.9139 3.5515 5.9649
IGROV-1 GDSC1 4.4061 6.1722 3.466 6.4514
EFO-27 GDSC1 4.4404 5.802 3.6782 4.6638
TYK-nu GDSC1 4.6075 5.7288 3.84 2.8832
OVCAR-8 GDSC1 4.6299 6.3522 3.5506 5.0547
OVK18 GDSC1 4.6653 8.0445 2.7385 11.2138
SK-OV-3 GDSC1 4.7937 6.2793 3.703 3.4138
RMG-I GDSC1 4.896 6.5181 3.6575 3.489
TOV-21G GDSC1 4.943 6.2563 3.8103 2.2629
ES-2 GDSC1 4.9979 6.5569 3.705 2.8931
OVTOKO GDSC1 5.2538 7.6363 3.3621 4.782
OVISE GDSC1 5.5077 10.821 1.9998 13.7711
OVCAR-4 GDSC1 5.664 7.7951 3.5352 2.7106
DOV13 GDSC1 6.2121 8.5012 3.5182 1.9648
OV-90 GDSC1 6.2954 8.1055 3.7142 0.898
OVCAR-3 GDSC1 6.7861 8.2913 3.8378 0.2314
EFO-21 GDSC1 6.8605 8.3526 3.8432 0.1997
OAW28 GDSC1 6.9002 8.8196 3.6939 0.5562
OVCAR-5 GDSC1 7.1201 8.9553 3.7285 0.3599
Kuramochi GDSC1 7.2684 8.9994 3.7666 0.2312
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PSN1 GDSC1 2.883 4.1106 2.8038 18.4991
MZ-PC-1 GDSC1 3.7149 4.7543 3.5063 9.0337
QGP-1 GDSC1 3.8694 5.1285 3.4992 8.3375
Capan-2 GDSC1 3.9883 5.5571 3.4083 8.5122
HuP-T3 GDSC1 4.2432 5.1368 3.8472 4.039
HPAC GDSC1 4.4345 6.0556 3.5471 5.7151
HuP-T4 GDSC1 4.4544 5.6502 3.7648 3.9372
HPAF-II GDSC1 4.4814 6.3948 3.4152 6.5931
PL4 GDSC1 4.5066 5.8899 3.686 4.3848
KP-2 GDSC1 4.6264 5.8161 3.8109 3.0523
Capan-1 GDSC1 4.6722 6.231 3.6412 4.2255
SUIT-2 GDSC1 4.7603 6.1549 3.7401 3.2231
CFPAC-1 GDSC1 4.8265 6.4574 3.6398 3.8033
KP-4 GDSC1 4.8816 6.2479 3.7759 2.6514
PaTu 8902 GDSC1 4.9693 6.7381 3.6014 3.721
Panc 10.05 GDSC1 5.058 6.4643 3.7842 2.2006
Panc 03.27 GDSC1 5.3001 6.9151 3.7213 2.1541
BxPC-3 GDSC1 5.4693 8.3955 3.1436 5.8496
SW1990 GDSC1 5.4892 7.451 3.5898 2.672
KP-3 GDSC1 5.556 8.9535 2.9362 7.1351
MIA PaCa-2 GDSC1 5.8834 7.2104 3.881 0.5485
PaTu 8988t GDSC1 5.896 7.2433 3.8738 0.5669
SU.86.86 GDSC1 6.1305 7.428 3.899 0.3373
DAN-G GDSC1 6.1328 7.798 3.7626 0.831
YAPC GDSC1 6.5452 7.5825 3.9926 0.0529
Hs 766T GDSC1 6.6843 8.3445 3.7818 0.4056
Panc 02.03 GDSC1 6.6955 8.334 3.7897 0.3787
Panc 04.03 GDSC1 6.7381 8.2439 3.8369 0.2485
Panc 08.13 GDSC1 6.8007 8.5647 3.7474 0.4476
AsPC-1 GDSC1 7.6645 9.5483 3.719 0.215
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1 4.5213 6.7065 3.2914 7.4304
NCI-H2052 GDSC1 4.6785 7.0205 3.257 7.1871
MPP 89 GDSC1 5.2773 11.28 1.6035 16.955
MSTO-211H GDSC1 5.8122 8.2236 3.4284 3.1379
NCI-H2452 GDSC1 6.4915 8.4738 3.6567 0.9747
IST-Mes1 GDSC1 6.7565 8.538 3.74 0.4911
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 2.4109 4.0231 2.3097 24.5393
DU145 GDSC1 3.0592 3.8511 3.0382 15.9175
VCaP GDSC1 3.9046 5.4158 3.3975 8.9574
22Rv1 GDSC1 4.046 5.1888 3.6415 6.4565
LNCaP clone FGC GDSC1 4.3615 5.908 3.5617 5.8537
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 6.3034 8.2479 3.6626 1.1199
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IGR-1 GDSC1 2.5004 4.7222 2.2119 24.6721
Mel JuSo GDSC1 2.5839 3.6499 2.5577 21.8914
IPC-298 GDSC1 3.0541 4.0466 3.0026 16.1786
IST-MEL1 GDSC1 3.0664 4.6788 2.8401 17.2161
UACC-257 GDSC1 3.1661 3.9027 3.1455 14.5787
A-388 GDSC1 3.1754 4.2582 3.0875 14.905
SK-MEL-30 GDSC1 3.3096 4.6042 3.1289 13.8695
IGR-37 GDSC1 3.3826 4.6892 3.1774 13.1346
RPMI-7951 GDSC1 3.3867 4.8386 3.1251 13.4865
451Lu GDSC1 3.4174 4.4275 3.304 12.0588
CHL-1 GDSC1 3.425 4.2866 3.3525 11.6852
A-431 GDSC1 3.5059 4.5836 3.3483 11.2642
CP50-MEL-B GDSC1 3.7001 4.3099 3.6465 8.1242
Mel Ho GDSC1 3.7269 4.891 3.4614 9.3027
A-375 GDSC1 3.7627 4.7122 3.5738 8.2989
G-mel GDSC1 3.815 4.5531 3.692 7.1748
WM115 GDSC1 3.8364 4.8184 3.6059 7.6933
G-361 GDSC1 3.9146 5.961 3.1424 10.8878
LB2518-MEL GDSC1 4.0058 4.7292 3.8186 5.2853
LB373-MEL-D GDSC1 4.0675 4.7128 3.8882 4.4692
MMAc-SF GDSC1 4.1249 4.9709 3.8215 4.7232
SK-MEL-28 GDSC1 4.1886 4.6879 4.0186 2.9231
MZ-MEL-2 GDSC1 4.2008 5.4207 3.6686 5.6088
COLO 829 GDSC1 4.2515 5.942 3.4524 7.1167
SK-MEL-5 GDSC1 4.3173 6.2112 3.3734 7.4966
MZ-MEL-7 GDSC1 4.406 7.127 2.9888 10.1905
COLO 679 GDSC1 4.4121 6.3 3.407 6.8947
WM35 GDSC1 4.4649 7.1038 3.0483 9.5217
A101D GDSC1 4.4718 5.6949 3.756 3.9489
HMV-II GDSC1 4.5297 6.2366 3.5318 5.5186
A2058 GDSC1 4.5659 6.1984 3.5784 5.0373
SK-MEL-3 GDSC1 4.6664 10.6277 1.4513 19.8925
Hs 940.T GDSC1 4.6684 7.0208 3.2492 7.2799
Hs 938.T GDSC1 4.7032 6.139 3.7082 3.6218
GAK GDSC1 4.7136 6.6407 3.4705 5.4221
MeWo GDSC1 4.7304 5.9982 3.7949 2.8889
SK-MEL-24 GDSC1 4.7726 6.1332 3.7587 3.0505
COLO 800 GDSC1 4.8737 7.495 3.1685 7.2715
M14 GDSC1 5.2355 7.3848 3.4684 4.0515
VMRC-MELG GDSC1 5.2784 6.9231 3.7054 2.2998
COLO 783 GDSC1 5.4624 7.0439 3.7528 1.6783
SK-MEL-2 GDSC1 5.5112 6.9214 3.8286 1.1683
SK-MEL-1 GDSC1 5.6661 8.5947 3.1748 5.1661
WT2-iPS GDSC1 5.8222 7.2832 3.8271 0.828
SH-4 GDSC1 5.8998 8.2383 3.4698 2.7205
WM278 GDSC1 6.0016 8.4571 3.4295 2.8033
UACC-62 GDSC1 6.0972 7.371 3.9067 0.3313
RVH-421 GDSC1 6.1527 11.9192 1.9195 12.4876
WM793 GDSC1 6.2128 7.9483 3.7392 0.8623
HT-144 GDSC1 6.2506 10.1525 2.8141 6.3732
WM1552C GDSC1 6.2807 7.9797 3.7559 0.7385
DJM-1 GDSC1 6.3181 9.0026 3.3613 2.7187
CP66-MEL GDSC1 6.416 7.9629 3.8162 0.4384
LOX-IMVI GDSC1 6.4953 7.9748 3.842 0.3273
COLO 792 GDSC1 7.0531 9.1822 3.6218 0.7021
EquiPSC Line K2 GDSC1 6.1713 9.1663 3.2121 3.8913
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 1.3462 2.541 1.3417 37.2244
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 GDSC1 0.6488 2.4567 0.6301 45.9784
KYM-1 GDSC1 1.0473 1.6462 1.0473 40.9329
VA-ES-BJ GDSC1 1.2702 2.0912 1.27 38.1481
RD GDSC1 1.449 2.6732 1.4426 35.9513
EW-8 GDSC1 2.452 3.5163 2.4321 23.4998
A-204 GDSC1 2.4558 3.7374 2.4101 23.6176
Hs 633.T GDSC1 3.0269 4.1926 2.9417 16.7416
SK-LMS-1 GDSC1 3.4247 4.131 3.3875 11.4545
Rh41 GDSC1 3.5357 4.3097 3.4672 10.2764
Rh30 GDSC1 3.8202 4.4723 3.727 6.8997
MFH-ino GDSC1 3.8902 4.9963 3.5809 7.6221
HT-1080 GDSC1 4.1551 5.3466 3.6647 5.8204
G-402 GDSC1 4.2679 5.4461 3.7142 4.9919
SW982 GDSC1 4.4915 5.8057 3.7161 4.1978
SK-UT-1 GDSC1 4.5387 5.9485 3.6815 4.318
RKN GDSC1 4.6118 6.4132 3.5069 5.4509
SW872 GDSC1 5.1673 7.0451 3.5838 3.3771
MES-SA GDSC1 5.7989 8.4007 3.3422 3.7328
SW684 GDSC1 6.0943 7.3468 3.9142 0.3111
GCT GDSC1 6.9141 8.2934 3.8818 0.1253
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 746.T GDSC1 1.515 2.8926 1.5009 35.173
RF-48 GDSC1 1.802 5.0905 1.3294 34.2106
NUGC-4 GDSC1 2.1063 3.9011 2.0045 28.3431
MKN1 GDSC1 3.1268 4.3643 3.0058 15.7361
SCH GDSC1 3.1415 4.0091 3.1037 14.9974
ECC10 GDSC1 3.2245 4.9262 2.9183 15.818
RERF-GC-1B GDSC1 3.2375 5.6653 2.6194 17.9254
AGS GDSC1 3.4087 4.183 3.3595 11.7335
MKN28 GDSC1 3.4415 5.8458 2.7423 16.0414
HSC-39 GDSC1 3.5501 4.5283 3.4155 10.5526
GCIY GDSC1 3.709 5.1186 3.343 10.2713
HGC-27 GDSC1 3.8715 4.3333 3.8273 5.9212
23132/87 GDSC1 3.9315 5.2615 3.4971 8.072
NUGC-3 GDSC1 4.1746 5.3007 3.7049 5.4275
Fu97 GDSC1 4.6249 5.8776 3.7799 3.2947
SNU-1 GDSC1 4.7472 7.0374 3.3003 6.638
MKN45 GDSC1 5.1729 6.5695 3.8031 1.8496
OCUM-1 GDSC1 5.9355 7.9974 3.591 1.9328
SNU-5 GDSC1 6.1364 7.7584 3.7793 0.7581
TMK-1 GDSC1 6.2298 8.3939 3.5707 1.6569
SNU-16 GDSC1 6.2543 7.5046 3.918 0.2345
NCI-N87 GDSC1 6.3154 8.195 3.6884 0.9923
IM95 GDSC1 6.4808 8.3838 3.6865 0.86
MKN7 GDSC1 6.4993 8.4736 3.6601 0.9537
TGBC11TKB GDSC1 6.5399 8.4217 3.6968 0.7745
SNG-M GDSC1 1.8381 2.7897 1.8354 31.0648
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT2609-C02 GDSC1 2.1906 3.152 2.184 26.6828
8505C GDSC1 2.4193 3.9375 2.3364 24.3152
ML-1 [Human leukemia] GDSC1 3.3169 4.8655 3.0403 14.4598
B-CPAP GDSC1 3.5174 4.3159 3.4456 10.5274
CAL-62 GDSC1 3.5366 4.5364 3.398 10.7487
IHH-4 GDSC1 3.6962 4.3517 3.6307 8.2537
BHT-101 GDSC1 3.6978 4.2619 3.6562 8.0724
FTC-133 GDSC1 3.9467 4.5781 3.8223 5.5512
WRO GDSC1 4.0473 4.6374 3.9017 4.4646
HTC-C3 GDSC1 4.3311 5.6235 3.6787 5.0398
ASH-3 GDSC1 4.4695 5.664 3.7695 3.8509
8305C GDSC1 4.5399 6.3856 3.4656 6.0037
KMH-2 GDSC1 4.6354 7.4069 3.0323 9.0696
CGTH-W-1 GDSC1 4.7836 7.8638 2.9195 9.4553
K5 GDSC1 6.6898 8.3626 3.7774 0.4152
TT GDSC1 6.7132 8.2819 3.8146 0.3079
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SKN-3 GDSC1 1.9068 3.0798 1.8953 30.2614
SAS GDSC1 2.8591 3.5798 2.8516 18.332
PCI-04B GDSC1 3.4649 4.7391 3.2469 12.203
SCC-9 GDSC1 3.8266 4.3354 3.7776 6.5145
OSC-20 GDSC1 3.8562 5.033 3.5302 8.1647
JHU-011 GDSC1 3.8571 4.5627 3.7334 6.6574
HSC-4 GDSC1 3.9105 4.3458 3.8662 5.4351
HO-1-N-1 GDSC1 4.014 4.9948 3.7039 6.1173
SCC-25 GDSC1 4.1177 5.4743 3.5679 6.7304
BICR 31 GDSC1 4.2173 5.0405 3.8722 3.9451
BICR 10 GDSC1 4.2448 5.339 3.7477 4.8158
BB30-HNC GDSC1 4.2485 5.2193 3.8106 4.3065
HO-1-u-1 GDSC1 4.3038 5.7143 3.6106 5.6764
BHY GDSC1 4.4114 5.4135 3.8488 3.4198
Ca9-22 GDSC1 4.4321 5.6815 3.7317 4.2711
SCC-4 GDSC1 4.4404 5.7063 3.7258 4.2897
SCC-15 GDSC1 4.6008 6.3376 3.536 5.259
BICR 78 GDSC1 4.6215 6.0662 3.6851 4.0365
PCI-38 GDSC1 4.6387 6.84 3.3161 6.8534
CAL-27 GDSC1 4.7236 5.8277 3.8718 2.3319
LB771-HNC GDSC1 5.3256 8.5176 2.9902 7.3394
CAL-33 GDSC1 5.3852 7.3046 3.5958 2.8314
FaDu GDSC1 5.4478 7.0226 3.7543 1.6919
BB49-HNC GDSC1 5.7255 8.9855 3.0302 6.0521
JHU-022 GDSC1 5.7621 7.8003 3.5856 2.2261
NCI-H3118 GDSC1 5.9843 7.958 3.6313 1.6386
HSC-3 GDSC1 6.0517 7.4753 3.8507 0.5426
Detroit 562 GDSC1 6.1982 7.9134 3.7464 0.8443
PE/CA-PJ15 GDSC1 6.2165 7.9129 3.7543 0.796
PCI-15A GDSC1 6.3265 8.1114 3.7251 0.8263
HSC-2 GDSC1 6.3885 7.6286 3.9235 0.179
KON GDSC1 6.4221 8.42 3.6476 1.0759
BICR 22 GDSC1 6.5191 8.0648 3.819 0.3787
OSC-19 GDSC1 6.5348 8.4175 3.6962 0.7804
DOK GDSC1 6.8131 8.8527 3.6473 0.7666
PCI-30 GDSC1 6.821 8.577 3.7506 0.4287
PCI-06A GDSC1 6.9596 8.8269 3.714 0.4664
SAT [Human HNSCC] GDSC1 7.6395 10.0759 3.5258 0.6784
KOSC-2 GDSC1 7.6779 9.9804 3.5745 0.5218
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
647V GDSC1 2.2119 3.7255 2.1503 26.7673
BFTC-905 GDSC1 2.9061 3.602 2.8989 17.7429
639V GDSC1 3.3937 4.1788 3.3441 11.9242
RT-112 GDSC1 3.4511 4.3962 3.3503 11.5522
SW1710 GDSC1 3.6271 4.3943 3.5427 9.2444
RT-4 GDSC1 3.6971 5.248 3.2724 10.858
UM-UC-3 GDSC1 3.7177 4.3592 3.652 7.9869
5637 GDSC1 3.7203 4.4857 3.6143 8.2331
HT-1197 GDSC1 3.7662 4.2545 3.7324 7.1658
TCCSUP GDSC1 4.0695 4.7728 3.8626 4.6541
CAL-29 GDSC1 4.3623 5.491 3.7707 4.203
J82 GDSC1 5.2614 7.4945 3.4335 4.2437
T24 GDSC1 5.4753 7.7376 3.4527 3.6316
KU-19-19 GDSC1 5.6966 6.7824 3.9643 0.3712
SW780 GDSC1 6.4093 8.0306 3.789 0.5295
HT-1376 GDSC1 6.9078 8.8348 3.6913 0.5601
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NEC8 GDSC1 0.3206 1.7079 0.3183 50.0169
NT2-D1 GDSC1 1.1237 1.9659 1.1235 39.9792
C-33 A GDSC1 1.1471 3.096 1.0989 39.9428
JAR GDSC1 2.3599 3.538 2.333 24.6953
SKN GDSC1 2.4529 3.3177 2.4461 23.4055
PA-1 GDSC1 2.5161 4.6583 2.25 24.3276
OVCA420 GDSC1 3.1043 8.7811 1.011 28.6254
NCC-IT GDSC1 3.1344 4.101 3.0789 15.2015
OVMIU GDSC1 3.1793 9.6233 0.6677 29.8661
PEO1 GDSC1 3.3077 4.7202 3.0855 14.1854
ACC-OV7 GDSC1 3.3094 4.4159 3.1899 13.4478
HEY GDSC1 3.3259 4.5513 3.1647 13.5304
SW756 GDSC1 3.4808 4.174 3.4397 10.7796
Ca Ski GDSC1 3.6489 4.5784 3.5043 9.3929
HT-3 GDSC1 3.6814 4.6392 3.5164 9.1343
OVCA433 GDSC1 3.6841 4.3899 3.6062 8.4888
OV17R GDSC1 3.8166 4.7602 3.6103 7.7594
JEG-3 GDSC1 3.859 6.0443 3.0499 11.8386
SW954 GDSC1 3.9457 4.6836 3.7771 5.8876
BPH-1 GDSC1 3.953 5.3147 3.4923 8.0141
SiSo GDSC1 4.0042 5.1209 3.6344 6.6943
SW962 GDSC1 4.0264 5.4064 3.5173 7.5042
DoTc2 4510 GDSC1 4.0737 5.0155 3.7515 5.4864
JHOS-3 GDSC1 4.2181 5.5406 3.624 5.892
KGN GDSC1 4.2287 6.972 2.9185 11.3831
UWB1.289 GDSC1 4.2805 5.672 3.612 5.7507
DSH1 GDSC1 4.4408 5.6999 3.7293 4.2608
CAL-39 GDSC1 4.4775 6.692 3.2639 7.7938
LB831-BLC GDSC1 4.4799 5.8965 3.6621 4.6593
MS751 GDSC1 4.5632 5.9741 3.6873 4.1966
OMC-1 [Human cervical carcinoma] GDSC1 4.7062 6.3799 3.5929 4.4981
HEC-1 GDSC1 5.0007 6.3903 3.7838 2.3246
ME-180 GDSC1 5.0111 6.8814 3.5609 3.9163
C-4-I GDSC1 5.4418 7.1031 3.7164 1.9365
SiHa GDSC1 5.5371 6.841 3.8735 0.9001
HeLa GDSC1 5.7644 6.7517 4.0015 0.2222
SKG-IIIa GDSC1 6.1364 7.7621 3.7779 0.7637
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 Emerging therapies targeting the ubiquitin proteasome system in cancer. J Clin Invest. 2014 Jan;124(1):6-12.