Details of the Drug

General Information of Drug (ID: DMO7492)

Drug Name
ISIS 343867
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
siRNA drug
Sequence
5'-UUUGAAAAUGWUGAUCUCC-3'
Cross-matching ID
TTD ID
D05FGY

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Survivin messenger RNA (Survivin mRNA) TTEWOHV BIRC5_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Survivin messenger RNA (Survivin mRNA) DTT BIRC5 1.67E-190 1.63 5.29
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 US patent application no. 7,541,344, Modulation of survivin expression.