Details of the Drug

General Information of Drug (ID: DMOTGEK)

Drug Name
Pyrido[4,3-d]pyrimidin-5(6H)-one derivative 1
Synonyms PMID25684022-Compound-WO2010019637
Indication
Disease Entry ICD 11 Status REF
Metastatic cancer 2D50-2E2Z Patented [1]
Solid tumour/cancer 2A00-2F9Z Patented [1]
Drug Type
Small molecular drug
Cross-matching ID
TTD ID
D0ZV9P
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pyruvate dehydrogenase kinase 1 (PDHK1) TTCZOF2 PDK1_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 PDK1 disruptors and modulators: a patent review.Expert Opin Ther Pat. 2015 May;25(5):513-37.