Details of the Drug

General Information of Drug (ID: DMOZ84C)

Drug Name
US10077269, Example 6
Synonyms
SCHEMBL17492361; US10077269, Example 6; KZFDLYSKEWBCTB-UHFFFAOYSA-N; BDBM285533; N-Cyclopropyl-3-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazo[1,2-b]pyridazine-2-carboxamide (6); N-Cyclopropyl-3-([1,2,4]triazolo[1,5-a]pyridin-6-yl )imidazo[1,2-b]pyridazine-2-carboxamide
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 319.32
Logarithm of the Partition Coefficient (xlogp) 1
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C16H13N7O
IUPAC Name
N-cyclopropyl-3-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazo[1,2-b]pyridazine-2-carboxamide
Canonical SMILES
C1CC1NC(=O)C2=C(N3C(=N2)C=CC=N3)C4=CN5C(=NC=N5)C=C4
InChI
InChI=1S/C16H13N7O/c24-16(20-11-4-5-11)14-15(23-13(21-14)2-1-7-18-23)10-3-6-12-17-9-19-22(12)8-10/h1-3,6-9,11H,4-5H2,(H,20,24)
InChIKey
KZFDLYSKEWBCTB-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
118863057
ChEBI ID
CHEMBL4455799
TTD ID
D05TQB
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Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 4C (PDE4C) TT6A59G PDE4C_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Imidazopyridazine compounds. US9598421.