Details of the Drug

General Information of Drug (ID: DMP35VS)

Drug Name
SGC0946
Synonyms
SGC0946; 1561178-17-3; SGC 0946; CHEMBL3087498; SGC-0946; 5-Bromo-7-{5-[(3-{[(4-Tert-Butylphenyl)carbamoyl]amino}propyl)(Propan-2-Yl)amino]-5-Deoxy-Beta-D-Ribofuranosyl}-7h-Pyrrolo[2,3-D]pyrimidin-4-Amine; 1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea; MLS006011035; C28H40BrN7O4; GTPL7020; SCHEMBL17433345; AOB3554; EX-A321; MolPort-028-720-498; ZINC97956664; s7079; BDBM50443016; 2714AH; AKOS024458211
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 618.6
Logarithm of the Partition Coefficient (xlogp) 3
Rotatable Bond Count (rotbonds) 10
Hydrogen Bond Donor Count (hbonddonor) 5
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C28H40BrN7O4
IUPAC Name
1-[3-[[(2R,3S,4R,5R)-5-(4-amino-5-bromopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea
Canonical SMILES
CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=C(C4=C(N=CN=C43)N)Br)O)O
InChI
InChI=1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,15-16,20,22-23,26,37-38H,6,11-12,14H2,1-5H3,(H2,30,32,33)(H2,31,34,39)/t20-,22-,23-,26-/m1/s1
InChIKey
IQCKJUKAQJINMK-HUBRGWSESA-N
Cross-matching ID
PubChem CID
56962337
CAS Number
1561178-17-3
TTD ID
D0S9SJ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone-lysine N-methyltransferase (HLNM) TTSZ8T1 DOT1L_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Histone-lysine N-methyltransferase (HLNM) DTT DOT1L 7.62E-02 0.08 0.2
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 1.0347 3.077 -1.6949 0.9905
EW-24 GDSC1; GDSC2 0.0305 1.7611 -1.6458 1.891
CAL-72 GDSC1; GDSC2 0.7251 3.0966 -1.8521 1.9946
CADO-ES1 GDSC1; GDSC2 0.7542 2.6961 -1.6713 1.1419
HOS GDSC1; GDSC2 0.8181 7.3313 -3.765 12.3207
NOS-1 [Human HNSCC] GDSC1; GDSC2 0.9106 3.1434 -1.7791 1.4479
EW-13 GDSC1; GDSC2 0.9331 2.8175 -1.6383 0.8591
ES1 GDSC1; GDSC2 1.024 3.4801 -1.8627 1.6991
EW-7 GDSC1; GDSC2 1.11 3.0738 -1.6607 0.8085
SK-PN-DW GDSC1; GDSC2 1.133 3.2729 -1.7281 1.0367
EW-3 GDSC1; GDSC2 1.1445 4.2368 -2.121 2.7813
U2OS GDSC1; GDSC2 1.1481 3.4032 -1.7728 1.1976
A-673 GDSC1; GDSC2 1.1517 3.1671 -1.6787 0.8417
HuO-3N1 GDSC1; GDSC2 1.1706 3.4211 -1.7697 1.166
MG-63 GDSC2 1.209 4.5661 -2.2292 3.238
EW-16 GDSC1; GDSC2 1.2147 4.5047 -2.1994 3.0797
TC-71 GDSC1; GDSC2 1.2865 2.8227 -1.4978 0.2616
CHSA8926 GDSC1; GDSC2 1.2886 3.8307 -1.8793 1.504
U-CH2 GDSC2 1.3184 3.2138 -1.6268 0.5698
H-EMC-SS GDSC1; GDSC2 1.3212 4.3104 -2.0612 2.2761
EW-11 GDSC1; GDSC2 1.3272 4.9488 -2.332 3.5975
CAL-78 GDSC1; GDSC2 1.3397 3.668 -1.7912 1.109
EW-22 GDSC1; GDSC2 1.3448 3.3523 -1.6677 0.6785
SaOS-2 GDSC1; GDSC2 1.3464 3.5527 -1.7434 0.9296
MHH-ES-1 GDSC1; GDSC2 1.3738 4.1438 -1.9663 1.791
ES5 GDSC1; GDSC2 1.3941 4.0157 -1.9047 1.5101
EW-1 GDSC1; GDSC2 1.4279 3.7317 -1.7773 0.9904
ES6 GDSC1; GDSC2 1.4387 4.4703 -2.0694 2.1812
SK-ES-1 GDSC1; GDSC2 1.4663 3.2336 -1.576 0.3676
EW-18 GDSC1; GDSC2 1.5288 3.4227 -1.6201 0.4483
NY GDSC1; GDSC2 1.5519 3.8126 -1.7554 0.8301
ES8 GDSC1; GDSC2 1.5563 3.7003 -1.7113 0.6883
HuO9 GDSC1; GDSC2 1.6684 6.2813 -2.7308 5.1589
SJSA-1 GDSC1; GDSC2 1.7394 3.5543 -1.5874 0.2954
EW-12 GDSC2 1.756 3.9302 -1.716 0.5947
CHSA0108 GDSC1; GDSC2 1.7728 4.221 -1.8176 0.8917
ES4 GDSC1; GDSC2 1.8683 4.0081 -1.7003 0.501
CHSA0011 GDSC1; GDSC2 1.8804 4.5481 -1.8969 1.0859
G-292 clone A141B1 GDSC1; GDSC2 1.8934 10.7239 -4.6612 14.3836
ES7 GDSC1; GDSC2 2.4072 4.4352 -1.6512 0.2281
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 1.0429 3.0683 -1.6879 0.9572
OCI-Ly7 GDSC2 -0.186 2.9181 -2.3291 6.3159
NB4 GDSC1; GDSC2 -0.0885 3.6946 -2.6378 7.9699
BC-3 GDSC2 0.1895 2.7965 -2.0223 3.721
BONNA-12 GDSC2 0.3884 6.2642 -3.5501 12.1473
CML-T1 GDSC1; GDSC2 0.3902 2.3659 -1.7143 1.7428
MC116 GDSC1; GDSC2 0.5502 7.7234 -4.1469 14.8962
SR GDSC1; GDSC2 0.5797 2.5168 -1.6816 1.3635
MHH-CALL-4 GDSC2 0.6054 10.5335 -5.4896 20.7121
Farage GDSC1; GDSC2 0.6107 3.0519 -1.8933 2.3496
MV4-11 GDSC1; GDSC2 0.631 6.5536 -3.519 11.4215
SIG-M5 GDSC2 0.6478 7.5662 -3.9996 13.9225
EoL-1 GDSC1; GDSC2 0.6571 3.0336 -1.8607 2.1233
SCC-3 GDSC2 0.6617 1.7446 -1.35 0.1669
SU-DHL-10 GDSC1; GDSC2 0.6675 2.4053 -1.5949 0.9098
SU-DHL-8 GDSC1; GDSC2 0.6691 2.6605 -1.6974 1.3386
SUP-M2 GDSC1; GDSC2 0.6712 3.2858 -1.9626 2.6209
SKM-1 GDSC1; GDSC2 0.6872 2.4535 -1.605 0.9327
RPMI-8226 GDSC1; GDSC2 0.7028 4.0589 -2.2907 4.3404
MOLM-16 GDSC1; GDSC2 0.729 3.2828 -1.93 2.3752
L-363 GDSC1; GDSC2 0.7382 2.3493 -1.5417 0.6571
Ramos.2G6.4C10 GDSC1; GDSC2 0.7439 3.2032 -1.8878 2.1457
Daudi GDSC1; GDSC2 0.7506 2.6966 -1.6732 1.1533
P12-Ichikawa GDSC1; GDSC2 0.7506 2.5012 -1.5953 0.8424
Kasumi-1 GDSC1; GDSC2 0.7841 6.6845 -3.4763 10.8507
ME1 GDSC1; GDSC2 0.7857 2.1426 -1.445 0.3347
OCI-M1 GDSC1; GDSC2 0.7866 1.8777 -1.3509 0.1346
TUR GDSC1; GDSC2 0.7924 2.3335 -1.5129 0.5263
L-540 GDSC1; GDSC2 0.793 2.9089 -1.7395 1.3957
L-428 GDSC1; GDSC2 0.8072 2.8149 -1.6945 1.1885
OPM-2 GDSC1; GDSC2 0.8158 2.4232 -1.537 0.5892
WSU-DLCL2 GDSC1; GDSC2 0.8298 2.0831 -1.4068 0.227
CMK GDSC1 0.8376 1.8729 -1.3313 0.118
Karpas-422 GDSC1; GDSC2 0.8558 3.3242 -1.8815 1.9766
JVM-3 GDSC1; GDSC2 0.8675 3.8605 -2.107 3.0901
DEL GDSC1; GDSC2 0.8715 2.0243 -1.371 0.1466
H9 GDSC1; GDSC2 0.889 4.9678 -2.5952 5.717
Karpas-231 GDSC1; GDSC2 0.9023 2.0888 -1.3822 0.1576
P30/OHK GDSC1; GDSC2 0.9069 2.8884 -1.678 1.0313
JeKo-1 GDSC1; GDSC2 0.9199 2.4382 -1.5001 0.418
IM-9 GDSC1; GDSC2 0.9236 2.6386 -1.5735 0.6393
KG-1 GDSC1; GDSC2 0.9246 3.1989 -1.7951 1.5038
BALL-1 GDSC1; GDSC2 0.951 2.6216 -1.5557 0.565
NALM-6 GDSC1; GDSC2 0.9529 2.6485 -1.565 0.5932
ST486 GDSC1; GDSC2 0.9563 3.2039 -1.7819 1.4142
MOLT-16 GDSC1; GDSC2 0.9589 2.1646 -1.388 0.1529
NOMO-1 GDSC1; GDSC2 0.9592 2.2423 -1.4149 0.2011
OCI-AML-5 GDSC1; GDSC2 0.9605 2.0955 -1.3638 0.1152
SU-DHL-4 GDSC1; GDSC2 0.9608 2.1855 -1.3945 0.1635
Karpas-45 GDSC1; GDSC2 0.9685 2.8275 -1.6268 0.7909
NK-92MI GDSC2 0.9712 3.7429 -2.0001 2.4077
A3/Kawakami GDSC1; GDSC2 0.9791 2.0712 -1.3492 0.0922
Jiyoye GDSC1; GDSC2 0.9796 2.6213 -1.5439 0.5122
AMO1 GDSC1; GDSC2 0.982 3.8705 -2.0493 2.6373
DB GDSC1; GDSC2 0.9832 3.645 -1.9522 2.1605
SK-MM-2 GDSC1; GDSC2 0.9912 3.033 -1.6971 1.0346
RC-K8 GDSC1; GDSC2 0.992 2.6985 -1.5677 0.5776
EB2 GDSC1; GDSC2 0.9964 2.4869 -1.4879 0.3497
RL GDSC1; GDSC2 1.0012 5.4162 -2.7333 6.2861
SUP-HD1 GDSC1; GDSC2 1.0019 3.5852 -1.9174 1.9743
HT GDSC1; GDSC2 1.0345 2.5201 -1.4851 0.3268
Reh GDSC1; GDSC2 1.0367 2.5989 -1.5128 0.3956
SU-DHL-5 GDSC1; GDSC2 1.0368 2.2671 -1.3954 0.1459
MN-60 GDSC1; GDSC2 1.063 3.437 -1.8261 1.498
OCI-AML-3 GDSC1 1.0784 2.7411 -1.5484 0.5881
BE-13 GDSC1; GDSC2 1.0846 2.7543 -1.5508 0.4757
KOPN-8 GDSC1; GDSC2 1.099 2.9846 -1.6313 0.7157
PF-382 GDSC1; GDSC2 1.1036 3.5615 -1.8576 1.5932
MOLM-13 GDSC1; GDSC2 1.1048 2.9406 -1.6121 0.6494
Sc-1 GDSC1 1.106 2.8902 -1.5927 0.7318
GA-10 GDSC1; GDSC2 1.1087 2.575 -1.4766 0.2783
VL51 GDSC1; GDSC2 1.1091 2.8156 -1.5636 0.4993
CESS GDSC1; GDSC2 1.1151 2.5496 -1.4652 0.2517
KY821 GDSC1; GDSC2 1.1176 2.7955 -1.5528 0.4643
SUP-T1 GDSC1; GDSC2 1.1253 3.6657 -1.8899 1.7126
P31/FUJ GDSC1; GDSC2 1.1266 2.237 -1.3541 0.0749
SUP-B8 GDSC1; GDSC2 1.1284 3.2648 -1.7269 1.036
RPMI-6666 GDSC1; GDSC2 1.1318 2.946 -1.603 0.6041
Hs 445 GDSC1; GDSC2 1.1319 7.7101 -3.732 11.4693
SU-DHL-16 GDSC1; GDSC2 1.1426 2.5897 -1.4691 0.2507
NCI-H929 GDSC1; GDSC2 1.1462 6.6053 -3.1973 8.5802
Karpas-620 GDSC1; GDSC2 1.1581 2.3901 -1.3946 0.1186
OCI-AML-2 GDSC1; GDSC2 1.1587 2.2471 -1.3465 0.0632
EHEB GDSC1 1.1616 3.5631 -1.8307 1.7695
A4/Fukuda GDSC1; GDSC2 1.1659 2.7288 -1.5098 0.3319
Karpas-1106P GDSC1; GDSC2 1.1706 2.9201 -1.5775 0.5066
NU-DUL-1 GDSC1; GDSC2 1.1916 2.6955 -1.4882 0.2738
Karpas-299 GDSC1; GDSC2 1.1922 3.1162 -1.6421 0.6909
MHH-CALL-2 GDSC1; GDSC2 1.199 2.8276 -1.5326 0.3733
HDLM-2 GDSC1; GDSC2 1.2132 3.9553 -1.9667 1.9629
HL-60 GDSC1; GDSC2 1.2133 2.4404 -1.3924 0.1055
EM-2 GDSC1; GDSC2 1.2165 3.2041 -1.6652 0.7512
Loucy GDSC1; GDSC2 1.2203 3.1182 -1.6311 0.6389
U266B1 GDSC1; GDSC2 1.2286 2.7638 -1.4985 0.2829
THP-1 GDSC1; GDSC2 1.2295 2.9997 -1.5834 0.4927
WSU-NHL GDSC1; GDSC2 1.2297 2.6097 -1.4443 0.1784
KMS-12-BM GDSC2 1.2325 2.8734 -1.5362 0.3679
MOLT-4 GDSC1; GDSC2 1.2411 3.0337 -1.5913 0.5088
U-698-M GDSC1; GDSC2 1.2434 3.0768 -1.6063 0.5507
HH [Human lymphoma] GDSC1; GDSC2 1.2434 3.4096 -1.7327 0.9675
SUP-B15 GDSC2 1.2554 2.8173 -1.5075 0.2927
P32/ISH GDSC1; GDSC2 1.2672 2.4984 -1.3933 0.0975
BL-41 GDSC1; GDSC2 1.2878 3.4881 -1.7438 0.9742
CTB-1 GDSC1; GDSC2 1.2982 3.653 -1.8039 1.1912
K-562 GDSC1; GDSC2 1.2999 3.0323 -1.5676 0.4169
KE-37 GDSC1; GDSC2 1.3156 2.9177 -1.5205 0.2993
RPMI-8866 GDSC1; GDSC2 1.3247 2.8914 -1.5078 0.2695
LP-1 GDSC1; GDSC2 1.3312 2.8802 -1.5014 0.2545
TK [Human B-cell lymphoma] GDSC1; GDSC2 1.349 2.978 -1.5293 0.3066
CTV-1 GDSC1; GDSC2 1.3561 3.0344 -1.5467 0.3429
BV-173 GDSC1; GDSC2 1.3588 3.4817 -1.7109 0.8092
MY-M12 GDSC2 1.3807 15.1245 -7.1744 24.5272
ARH-77 GDSC1; GDSC2 1.3848 3.4567 -1.6905 0.726
MOLT-13 GDSC1; GDSC2 1.3854 3.1601 -1.5807 0.4122
Raji GDSC1; GDSC2 1.3875 2.8359 -1.4657 0.1745
Namalwa GDSC1; GDSC2 1.3909 2.9575 -1.5066 0.2459
Granta-519 GDSC1; GDSC2 1.4033 3.092 -1.5494 0.331
DoHH2 GDSC2 1.4048 2.9067 -1.4839 0.2005
KCL-22 GDSC1; GDSC2 1.4078 3.461 -1.6826 0.6871
DG-75 GDSC1; GDSC2 1.4088 3.6343 -1.748 0.9013
KM-H2 GDSC1; GDSC2 1.4151 3.5704 -1.7209 0.8053
OCI-Ly19 GDSC1; GDSC2 1.42 3.0408 -1.525 0.2732
JURL-MK1 GDSC1; GDSC2 1.4216 3.4359 -1.6675 0.6332
PL-21 GDSC1; GDSC2 1.4338 3.7119 -1.7671 0.9501
JJN-3 GDSC1; GDSC2 1.4387 3.0685 -1.5278 0.2728
ALL-SIL GDSC1; GDSC2 1.4561 3.1737 -1.5586 0.3318
HEL GDSC1; GDSC2 1.4711 4.4503 -2.0452 2.0372
RCH-ACV GDSC1; GDSC2 1.4767 4.4244 -2.0318 1.9718
L-1236 GDSC1; GDSC2 1.4805 4.0714 -1.8872 1.3621
LC4-1 GDSC1; GDSC2 1.4849 3.6636 -1.727 0.7805
EJM GDSC1; GDSC2 1.5008 3.3464 -1.6033 0.4187
LAMA-84 GDSC1; GDSC2 1.5049 3.108 -1.5174 0.2326
ATN-1 GDSC1; GDSC2 1.5106 2.9861 -1.4734 0.1584
Ku812 GDSC1; GDSC2 1.5147 3.3758 -1.6086 0.4257
ML-2 GDSC1; GDSC2 1.5187 3.1902 -1.541 0.2735
MLMA GDSC1; GDSC2 1.53 4.2737 -1.9453 1.5515
WIL2 NS GDSC1; GDSC2 1.5325 2.9842 -1.4651 0.142
SU-DHL-6 GDSC1; GDSC2 1.5347 3.1207 -1.511 0.2131
HAL-01 GDSC1; GDSC2 1.5449 3.0605 -1.4867 0.1709
ROS-50 GDSC1; GDSC2 1.5463 3.4846 -1.6357 0.4805
RS4;11 GDSC1; GDSC2 1.5656 3.2253 -1.5361 0.2497
MM1.S GDSC2 1.5658 3.1987 -1.5268 0.2325
JSC-1 GDSC1; GDSC2 1.5777 3.928 -1.7884 0.9233
CCRF-CEM GDSC1; GDSC2 1.594 3.4264 -1.5964 0.365
YT GDSC1; GDSC2 1.6074 3.1266 -1.4872 0.158
HC-1 GDSC1; GDSC2 1.6163 3.1202 -1.4819 0.1486
MHH-PREB-1 GDSC1; GDSC2 1.6221 3.219 -1.5135 0.1951
MEG-01 GDSC1; GDSC2 1.6289 3.7895 -1.715 0.6585
CRO-AP2 GDSC1; GDSC2 1.6415 3.8245 -1.7228 0.6749
GR-ST GDSC1; GDSC2 1.6439 4.0225 -1.7964 0.9057
TALL-1 [Human adult T-ALL] GDSC2 1.6507 3.8853 -1.7418 0.7266
697 GDSC1; GDSC2 1.6546 3.2063 -1.4977 0.1633
VAL GDSC1; GDSC2 1.6705 3.8461 -1.7191 0.6482
JVM-2 GDSC1; GDSC2 1.6835 3.9429 -1.7499 0.7323
Jurkat GDSC1; GDSC2 1.7222 2.934 -1.3843 0.0396
KMOE-2 GDSC1; GDSC2 1.7225 3.7392 -1.6595 0.4625
QIMR-WIL GDSC1; GDSC2 1.7272 4.3497 -1.8865 1.1605
BC-1 GDSC1; GDSC2 1.7475 3.5496 -1.5827 0.2838
MOLP-8 GDSC1; GDSC2 1.7941 3.4435 -1.5293 0.18
CA46 GDSC1; GDSC2 1.8023 4.2396 -1.8124 0.8562
Mono-Mac-6 GDSC1; GDSC2 1.8116 6.0922 -2.5679 4.1175
GDM-1 GDSC1; GDSC2 1.8256 3.9713 -1.7036 0.5283
DND-41 GDSC1; GDSC2 2.1767 3.957 -1.5696 0.1597
SU-DHL-1 GDSC2 2.1892 16.1247 -7.0719 22.57
ALL-PO GDSC1; GDSC2 2.323 4.4962 -1.7026 0.339
KMS-11 GDSC1; GDSC2 2.3486 11.0983 -4.5379 12.943
RPMI-8402 GDSC1; GDSC2 3.1984 13.5976 -5.1669 14.0571
NKM-1 GDSC1; GDSC2 4.736 16.5392 -5.5755 13.1045
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC1; GDSC2 0.8799 3.0726 -1.7648 1.4171
ESO-26 GDSC1; GDSC2 0.9785 3.4508 -1.8729 1.7951
KYSE-220 GDSC1; GDSC2 1.2358 3.4466 -1.7505 1.039
KYAE-1 GDSC1; GDSC2 1.3297 3.0616 -1.5666 0.4014
HCE-4 GDSC1; GDSC2 1.3862 3.309 -1.6347 0.5565
ESO-51 GDSC1; GDSC2 1.3957 3.6517 -1.7603 0.9536
SK-GT-4 GDSC1; GDSC2 1.5185 8.7538 -3.9714 11.8904
TE-12 GDSC1; GDSC2 1.5836 4.5189 -2.0192 1.8092
OACP4 C GDSC1; GDSC2 1.6406 5.3334 -2.3311 3.1751
OACM5.1 C GDSC1; GDSC2 1.7492 4.2722 -1.8471 1.0059
FLO-1 GDSC1; GDSC2 1.9293 5.5095 -2.2591 2.5007
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 1.5455 4.0127 -1.835 1.1108
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC2 -0.0701 8.5165 -5.0072 20.4513
SJNB-7 GDSC1; GDSC2 0.4644 9.1905 -4.9323 18.7694
KP-N-YN GDSC1; GDSC2 0.658 3.1115 -1.8938 2.2879
TGW GDSC1; GDSC2 0.6677 3.6965 -2.1471 3.6076
NB1 GDSC1; GDSC2 0.6842 2.6866 -1.7008 1.3379
SK-N-BE(2)-M17 GDSC1; GDSC2 0.721 2.8918 -1.7678 1.6003
KP-N-YS GDSC2 0.7968 3.0697 -1.8043 1.6833
SK-N-DZ GDSC1; GDSC2 0.8813 2.6358 -1.5905 0.7258
IMR-5 GDSC1; GDSC2 0.9124 2.5875 -1.5588 0.5985
SJNB-17 GDSC1; GDSC2 0.9238 3.2358 -1.8107 1.5734
SJNB-10 GDSC1; GDSC2 0.9347 2.649 -1.5728 0.6298
CHP-126 GDSC1; GDSC2 0.9709 4.408 -2.2918 3.9124
GOTO GDSC1; GDSC2 1.003 4.1695 -2.1681 3.2134
SiMa GDSC1 1.0092 3.1691 -1.7431 1.4961
SK-N-MC-IXC GDSC1; GDSC2 1.0865 2.1643 -1.3435 0.0695
SJNB-14 GDSC1; GDSC2 1.1058 2.7104 -1.5264 0.3989
SK-N-AS GDSC1; GDSC2 1.1212 3.4801 -1.8161 1.3987
SJNB-5 GDSC1; GDSC2 1.1246 2.7045 -1.5169 0.3664
NH-12 GDSC2 1.1912 2.9285 -1.5724 0.4817
Kelly GDSC1; GDSC2 1.2025 4.7812 -2.3271 3.7507
MHH-NB-11 GDSC2 1.2325 3.0446 -1.5987 0.5347
SK-N-FI GDSC1; GDSC2 1.239 2.8409 -1.522 0.3316
KP-N-RT-BM-1 GDSC2 1.4685 3.6674 -1.7352 0.818
SJNB-13 GDSC1; GDSC2 1.4711 3.057 -1.512 0.2323
NB(TU)1 GDSC1 1.4717 3.432 -1.6459 0.6774
SK-N-SH GDSC1; GDSC2 1.5398 5.7838 -2.5821 4.58
SJNB-6 GDSC2 1.5844 18.8956 -8.8846 28.2585
SJNB-12 GDSC1 1.6809 3.6842 -1.6557 0.5867
GI-ME-N GDSC1; GDSC2 1.6841 4.1528 -1.8292 0.9893
LA-N-6 GDSC1; GDSC2 1.6971 3.0917 -1.4445 0.0903
CHP-212 GDSC1; GDSC2 2.2165 11.91 -5.0112 15.25
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 0.5447 3.2048 -1.9974 2.9906
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-415 GDSC1; GDSC2 -0.339 1.4315 -1.7188 2.95
HCC202 GDSC1 0.2702 4.3016 -2.6815 9.1595
HCC1419 GDSC1; GDSC2 0.3564 3.1343 -2.0759 3.7307
CAL-120 GDSC1; GDSC2 0.5228 2.7062 -1.7907 1.95
HCC1187 GDSC1; GDSC2 0.5867 2.4634 -1.6562 1.2428
HCC1599 GDSC2 0.6605 4.2694 -2.413 5.101
BT-474 GDSC1; GDSC2 0.6769 2.9007 -1.7937 1.7728
HCC2157 GDSC1; GDSC2 0.7625 2.8652 -1.7363 1.4133
MRK-nu-1 GDSC1; GDSC2 0.7728 2.3953 -1.5446 0.6429
MDA-MB-231 GDSC1; GDSC2 0.7905 4.4429 -2.4136 4.8753
CAL-148 GDSC2 0.7924 2.5819 -1.6084 0.8582
UACC-812 GDSC2 0.8187 5.8408 -3.0493 8.4106
Evsa-T GDSC1; GDSC2 0.861 2.212 -1.4409 0.2921
DU4475 GDSC1; GDSC2 0.8701 2.559 -1.5658 0.6491
EFM-19 GDSC1; GDSC2 0.8796 5.4531 -2.8269 7.0372
BT-20 GDSC1; GDSC2 0.9008 2.655 -1.5894 0.7084
HCC1937 GDSC1; GDSC2 0.941 6.2182 -3.1479 8.7143
BT-483 GDSC1 0.9577 4.131 -2.1762 4.1225
MDA-MB-468 GDSC1; GDSC2 1.016 2.8258 -1.6058 0.6857
MDA-MB-175-VII GDSC1; GDSC2 1.0341 2.7437 -1.5673 0.5518
HCC38 GDSC1; GDSC2 1.0901 3.324 -1.7678 1.2287
AU565 GDSC2 1.0929 13.1162 -6.3988 22.808
CAMA-1 GDSC1; GDSC2 1.1032 2.7743 -1.5508 0.466
JIMT-1 GDSC1; GDSC2 1.132 3.1479 -1.6798 0.86
CAL-51 GDSC1; GDSC2 1.1688 3.3771 -1.7531 1.1029
HCC1500 GDSC1; GDSC2 1.1748 3.0813 -1.6361 0.6828
MCF-7 GDSC1; GDSC2 1.183 3.3742 -1.7456 1.0626
MDA-MB-361 GDSC1; GDSC2 1.1856 3.5371 -1.8091 1.3099
HCC70 GDSC1; GDSC2 1.2395 3.1669 -1.6415 0.6598
HDQ-P1 GDSC1; GDSC2 1.2434 7.4647 -3.5405 10.2339
BT-549 GDSC1; GDSC2 1.2463 3.9488 -1.9478 1.8421
EFM-192A GDSC1; GDSC2 1.2498 3.593 -1.802 1.2249
MFM-223 GDSC1; GDSC2 1.2877 3.0276 -1.5706 0.4302
CAL-85-1 GDSC1; GDSC2 1.3001 4.715 -2.2448 3.193
COLO 824 GDSC1; GDSC2 1.3113 4.0166 -1.9442 1.7586
HCC1806 GDSC1; GDSC2 1.3391 2.9662 -1.5288 0.3091
OCUB-M GDSC1; GDSC2 1.3398 3.5746 -1.7547 0.9746
ZR-75-30 GDSC1; GDSC2 1.3558 3.1519 -1.5892 0.4472
Hs 578T GDSC1; GDSC2 1.3622 3.338 -1.6552 0.6299
UACC-893 GDSC1; GDSC2 1.3657 4.0228 -1.9208 1.6044
HCC2218 GDSC1; GDSC2 1.4403 3.4963 -1.6825 0.6676
MDA-MB-453 GDSC1; GDSC2 1.4714 3.5355 -1.6844 0.6557
HCC1143 GDSC1; GDSC2 1.477 4.1681 -1.9275 1.5272
HCC1428 GDSC1; GDSC2 1.4879 3.0924 -1.5182 0.2389
MDA-MB-157 GDSC1; GDSC2 1.5035 3.3364 -1.5987 0.4063
MDA-MB-436 GDSC1; GDSC2 1.519 3.7318 -1.7385 0.7963
HCC1954 GDSC1; GDSC2 1.5657 3.122 -1.5003 0.1874
HCC1395 GDSC1; GDSC2 1.6306 7.0251 -3.0898 7.1113
YMB-1-E GDSC2 1.7151 10.229 -4.5447 14.2219
MDA-MB-330 GDSC1; GDSC2 1.8128 4.457 -1.8909 1.1132
HCC1569 GDSC1; GDSC2 1.9547 8.6543 -3.6432 9.4041
T-47D GDSC1; GDSC2 2.1146 4.3716 -1.7365 0.4854
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LN-18 GDSC1; GDSC2 -0.0142 1.6793 -1.6347 1.8993
42-MG-BA GDSC1; GDSC2 0.3291 6.6582 -3.7858 13.5622
U-251MG GDSC1; GDSC2 0.5833 3.3926 -2.0593 3.2643
SK-MG-1 GDSC1; GDSC2 0.7013 7.8707 -4.1099 14.3562
GaMG GDSC1; GDSC2 0.75 2.7619 -1.7 1.2675
LN-229 GDSC1; GDSC2 0.8223 9.2964 -4.7197 16.9733
CAS-1 GDSC1; GDSC2 0.8295 8.5876 -4.3678 15.323
ONS-76 GDSC1; GDSC2 0.8313 2.8176 -1.6843 1.1238
DK-MG GDSC1; GDSC2 0.8997 2.747 -1.6255 0.8378
D-502MG GDSC1; GDSC2 0.939 4.174 -2.2056 3.5029
D-263MG GDSC1; GDSC2 0.9549 2.7823 -1.6152 0.7599
SF295 GDSC1; GDSC2 0.9818 2.8576 -1.6327 0.8021
U-87MG ATCC GDSC1; GDSC2 0.9832 2.27 -1.4158 0.1956
DBTRG-05MG GDSC1; GDSC2 0.9878 3.0778 -1.7164 1.1134
H4 GDSC1; GDSC2 1.0107 3.6102 -1.9235 1.9923
Daoy GDSC1; GDSC2 1.0208 6.816 -3.3793 9.8232
AM-38 GDSC1; GDSC2 1.043 3.1341 -1.7137 1.0557
YKG-1 GDSC1; GDSC2 1.0436 2.6406 -1.5253 0.4258
YH-13 GDSC1; GDSC2 1.0547 2.5264 -1.4797 0.3058
A-172 GDSC1; GDSC2 1.0638 3.0376 -1.6667 0.8634
NMC-G1 GDSC1; GDSC2 1.0943 2.6344 -1.5033 0.3458
GI-1 GDSC1; GDSC2 1.1006 5.0622 -2.5111 4.8898
U-118MG GDSC1; GDSC2 1.1042 3.1698 -1.7005 0.956
KNS-42 GDSC1; GDSC2 1.1077 2.4287 -1.4257 0.1785
MOG-G-CCM GDSC1; GDSC2 1.1225 3.3373 -1.7583 1.1623
D-566MG GDSC1; GDSC2 1.132 2.91 -1.5894 0.5625
LNZTA3WT4 GDSC1; GDSC2 1.1363 2.9499 -1.6026 0.6002
KNS-81-FD GDSC1; GDSC2 1.1451 3.2991 -1.733 1.0455
M059J GDSC1; GDSC2 1.1548 3.2127 -1.695 0.8974
LN-405 GDSC1; GDSC2 1.1787 2.9262 -1.5765 0.4996
GB-1 GDSC1; GDSC2 1.1842 2.7474 -1.5095 0.3239
Hs 683 GDSC1; GDSC2 1.2418 2.9954 -1.5769 0.4687
SF539 GDSC1; GDSC2 1.2471 2.7869 -1.4998 0.2792
Onda 10 GDSC1; GDSC2 1.2967 3.0923 -1.5907 0.4793
SF126 GDSC1; GDSC2 1.3033 2.6772 -1.4412 0.1558
KINGS-1 GDSC1; GDSC2 1.3224 3.2362 -1.6335 0.5874
D283 Med GDSC1; GDSC2 1.3507 2.8722 -1.4915 0.2293
MOG-G-UVW GDSC1; GDSC2 1.3508 3.626 -1.7699 1.0213
D-245MG GDSC2 1.3793 6.2278 -2.8762 6.4019
D-542MG GDSC1; GDSC2 1.4019 2.9644 -1.5049 0.2395
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 1.4198 4.7765 -2.2081 2.8562
Becker GDSC1; GDSC2 1.4492 6.2149 -2.8284 6.0261
SW1783 GDSC1; GDSC2 1.5397 4.2383 -1.9266 1.4671
D-336MG GDSC1; GDSC2 1.5468 3.7808 -1.7455 0.8012
D-247MG GDSC1; GDSC2 1.5908 3.7615 -1.72 0.695
SF268 GDSC1; GDSC2 1.5967 4.1752 -1.8759 1.2223
SW1088 GDSC1; GDSC2 1.6689 3.3549 -1.5436 0.2341
T98G GDSC1; GDSC2 1.7322 15.6701 -7.1822 23.8122
8-MG-BA GDSC1; GDSC2 1.7491 12.3315 -5.5369 18.3174
D-392MG GDSC1; GDSC2 1.7561 4.0208 -1.7494 0.6899
SNB-75 GDSC1; GDSC2 1.7945 3.7803 -1.6467 0.4027
PFSK-1 GDSC2 1.8833 3.6257 -1.56 0.207
D-423MG GDSC1; GDSC2 2.0689 4.3636 -1.7512 0.5407
Onda 11 GDSC1; GDSC2 2.3328 4.1959 -1.596 0.1655
KALS-1 GDSC1; GDSC2 2.5582 10.3901 -4.0735 10.4262
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1; GDSC2 1.0574 3.0875 -1.689 0.9499
ETK-1 GDSC1; GDSC2 1.2296 4.8356 -2.336 3.7574
TGBC24TKB GDSC1; GDSC2 1.764 3.741 -1.6443 0.409
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1; GDSC2 0.8736 2.957 -1.7208 1.2353
ESS-1 GDSC1; GDSC2 1.1557 4.4277 -2.1977 3.1515
MFE-296 GDSC1; GDSC2 1.2191 3.2092 -1.6661 0.7523
MFE-319 GDSC1; GDSC2 1.2572 3.0447 -1.5889 0.494
KLE GDSC1; GDSC2 1.2764 3.3431 -1.6929 0.8039
EN GDSC1; GDSC2 1.6266 3.2856 -1.5349 0.2302
AN3-CA GDSC1; GDSC2 1.6543 3.6038 -1.637 0.4362
MFE-280 GDSC1; GDSC2 1.9748 4.5449 -1.8559 0.8881
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RCC10RGB GDSC1; GDSC2 -0.0024 3.603 -2.5325 7.137
KTCTL-1M GDSC1; GDSC2 0.4656 2.734 -1.8335 2.2438
A-498 GDSC1; GDSC2 0.5402 3.4474 -2.1091 3.6059
SW13 GDSC1; GDSC2 0.7475 3.1996 -1.8844 2.1244
786-O GDSC1; GDSC2 0.7824 3.936 -2.1885 3.6506
OS-RC-2 GDSC1; GDSC2 0.8449 3.5015 -1.9629 2.3864
KTCTL-13 GDSC1; GDSC2 0.8965 3.1759 -1.7992 1.5514
BFTC-909 GDSC1; GDSC2 0.9168 3.5977 -1.9664 2.3115
A-704 GDSC1; GDSC2 0.9622 2.973 -1.6864 1.0175
SN12C GDSC1; GDSC2 0.9744 2.828 -1.6244 0.7782
CAL-54 GDSC1; GDSC2 1.1072 3.2195 -1.7186 1.0215
VMRC-RCZ GDSC1; GDSC2 1.1465 2.9778 -1.6089 0.6137
RXF 393L GDSC1; GDSC2 1.1941 4.1186 -2.0448 2.3483
KTCTL-195 GDSC1; GDSC2 1.2083 11.0366 -5.2918 18.5277
VMRC-RCW GDSC2 1.2091 2.784 -1.5131 0.3225
TK-10 GDSC1; GDSC2 1.2178 5.0362 -2.4316 4.277
UO-31 GDSC1; GDSC2 1.2974 3.2444 -1.6468 0.6416
769-P GDSC1; GDSC2 1.3264 5.3691 -2.5183 4.5692
LB2241-RCC GDSC1; GDSC2 1.3572 3.4046 -1.6823 0.717
KTCTL-140 GDSC1; GDSC2 1.388 3.39 -1.6641 0.6419
LB996-RCC GDSC1; GDSC2 1.4801 3.8855 -1.8142 1.0847
KMRC-20 GDSC1; GDSC2 1.5622 3.358 -1.5841 0.3493
NCC021 GDSC1; GDSC2 1.6151 3.4292 -1.5895 0.3417
BB65-RCC GDSC1; GDSC2 1.6388 4.1775 -1.8583 1.1248
ACHN GDSC1; GDSC2 1.6391 3.2462 -1.5168 0.1963
NCC010 GDSC1; GDSC2 1.6429 4.2661 -1.8911 1.2425
KMRC-1 GDSC2 1.7075 12.5618 -5.6784 18.9427
KTCTL-26A GDSC1; GDSC2 1.7515 3.6147 -1.6041 0.3254
SW156 GDSC1; GDSC2 1.762 3.712 -1.6347 0.3878
KTCTL-21 GDSC1; GDSC2 1.97 4.3968 -1.8025 0.7286
HA7-RCC GDSC1; GDSC2 2.0315 4.4615 -1.8017 0.6936
LB1047-RCC GDSC1; GDSC2 2.0752 4.8081 -1.9135 1.0108
Caki-1 GDSC1; GDSC2 2.4136 4.391 -1.6339 0.2012
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2998 GDSC1; GDSC2 0.0215 3.4929 -2.4626 6.6633
SNU-283 GDSC2 0.0563 2.2656 -1.859 3.026
KM12 GDSC1; GDSC2 0.1804 3.984 -2.5901 7.081
LoVo GDSC1; GDSC2 0.4541 3.2865 -2.0869 3.6258
SNU-175 GDSC2 0.4797 5.2199 -2.9799 8.7233
COLO 678 GDSC1; GDSC2 0.4979 2.1073 -1.5536 0.8941
SNU-C1 GDSC1; GDSC2 0.7183 3.4464 -2.0072 2.7851
SNU-1040 GDSC1 0.7655 5.2965 -2.8265 8.9001
HT-55 GDSC2 0.7723 6.3086 -3.3036 9.9278
LS513 GDSC1; GDSC2 0.7862 8.7033 -4.4555 15.8398
SK-CO-1 GDSC1; GDSC2 0.8269 3.0283 -1.7723 1.5049
HT-29 GDSC1; GDSC2 0.8677 2.307 -1.4727 0.3693
COLO205 GDSC1; GDSC2 0.8707 2.5684 -1.5691 0.6598
SW1417 GDSC1; GDSC2 0.898 2.7559 -1.6297 0.8545
NCI-H747 GDSC1; GDSC2 0.9265 10.481 -5.2249 18.8983
COLO 320HSR GDSC1; GDSC2 0.9876 4.3471 -2.2551 3.6917
SW626 GDSC1; GDSC2 0.993 3.2614 -1.7879 1.4034
DiFi GDSC1; GDSC2 1.0012 4.7342 -2.4209 4.5618
LS1034 GDSC1; GDSC2 1.0155 2.6533 -1.5412 0.4847
CCK-81 GDSC1; GDSC2 1.0285 3.3984 -1.8269 1.536
SW48 GDSC1; GDSC2 1.0382 3.2792 -1.7738 1.3008
SW1463 GDSC1; GDSC2 1.0645 2.8947 -1.6116 0.6731
C2BBe1 GDSC1; GDSC2 1.0759 3.2398 -1.7407 1.1332
SNU-61 GDSC1; GDSC2 1.0812 3.5345 -1.8573 1.6149
LS411N GDSC1; GDSC2 1.0997 2.3226 -1.3921 0.127
NCI-H716 GDSC1; GDSC2 1.1224 3.1145 -1.6711 0.836
SW837 GDSC1; GDSC2 1.1792 3.0757 -1.6322 0.6672
SW948 GDSC1; GDSC2 1.1913 2.7851 -1.5203 0.3465
SW620 GDSC1; GDSC2 1.2021 6.8047 -3.2551 8.786
GP5d GDSC1; GDSC2 1.2026 2.6618 -1.4723 0.2374
SNU-81 GDSC1; GDSC2 1.2166 2.6474 -1.4621 0.2137
RCM-1 [Human ESC] GDSC1; GDSC2 1.222 2.7665 -1.502 0.2927
LS180 GDSC1; GDSC2 1.3128 2.7631 -1.4673 0.1962
T84 GDSC1; GDSC2 1.3371 4.0442 -1.9431 1.7276
LS123 GDSC1; GDSC2 1.3505 3.1143 -1.5776 0.4198
CaR-1 GDSC1; GDSC2 1.4231 3.6871 -1.7622 0.9405
SW1116 GDSC1; GDSC2 1.4386 3.8194 -1.8067 1.0888
HCT 15 GDSC1; GDSC2 1.528 3.1421 -1.5209 0.2324
SNU-C5 GDSC1; GDSC2 1.5322 3.9499 -1.8164 1.0535
NCI-H508 GDSC1; GDSC2 1.5324 3.3628 -1.5971 0.3907
CL-11 GDSC1; GDSC2 1.6322 4.0646 -1.8175 0.9855
HCT 116 GDSC1; GDSC2 1.6407 13.3185 -6.0956 20.5899
HT115 GDSC1; GDSC2 1.6553 2.8747 -1.387 0.0463
CW-2 GDSC1; GDSC2 1.6675 3.4168 -1.5657 0.2753
SNU-407 GDSC1; GDSC2 1.7199 3.7351 -1.659 0.4624
RKO GDSC1; GDSC2 1.8211 3.7461 -1.6246 0.3444
SNU-C2B GDSC1; GDSC2 2.0825 5.4575 -2.1646 1.941
MDST8 GDSC1; GDSC2 2.4408 15.424 -6.5512 20.4784
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 1.0869 2.9368 -1.6182 0.6803
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-6 GDSC1; GDSC2 -0.2001 6.754 -4.2323 17.2132
JHH-1 GDSC1; GDSC2 0.0511 2.4238 -1.9354 3.4729
HuH-1 GDSC1; GDSC2 0.4854 1.907 -1.4803 0.6229
Hep 3B2.1-7 GDSC1; GDSC2 0.5415 3.2596 -2.0237 3.1373
Hep-G2/C3A GDSC1; GDSC2 0.8113 2.1968 -1.4547 0.3482
Huh-7 GDSC1; GDSC2 0.8831 5.713 -2.9468 7.7056
JHH-7 GDSC1; GDSC2 0.9395 2.3918 -1.4755 0.3436
SK-HEP-1 GDSC1; GDSC2 0.9444 11.9125 -5.9161 21.5005
SNU-398 GDSC1; GDSC2 1.1083 4.3824 -2.2037 3.2478
JHH-4 GDSC1; GDSC2 1.1221 3.2464 -1.7225 1.0243
HLE GDSC1; GDSC2 1.2579 3.3473 -1.7024 0.8492
SNU-449 GDSC1; GDSC2 1.2885 3.4626 -1.7337 0.9371
SNU-387 GDSC1; GDSC2 1.3055 8.9639 -4.2161 13.5355
SNU-423 GDSC1; GDSC2 1.3412 3.4313 -1.6991 0.7817
JHH-2 GDSC1; GDSC2 1.5424 11.7935 -5.4216 18.3099
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2444 GDSC1; GDSC2 0.0649 1.8044 -1.6457 1.8391
NCI-H1304 GDSC1 0.1109 23.3525 -12.2634 38.2819
NCI-H841 GDSC1 0.2752 4.0843 -2.574 8.3814
RERF-LC-KJ GDSC1; GDSC2 0.3409 2.9957 -2.0219 3.4537
NCI-H647 GDSC1; GDSC2 0.3837 2.8863 -1.9471 2.9697
NCI-H1975 GDSC1; GDSC2 0.4434 3.0738 -1.9968 3.1461
LCLC-97TM1 GDSC1; GDSC2 0.5822 4.7115 -2.6693 6.7167
SHP-77 GDSC1; GDSC2 0.5859 5.8924 -3.2308 9.9229
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 0.5884 5.2712 -2.9311 8.2124
NCI-H2009 GDSC1; GDSC2 0.5971 2.5883 -1.7028 1.4406
NCI-H1703 GDSC1; GDSC2 0.599 3.2154 -1.9715 2.7715
NCI-H250 GDSC2 0.61 4.0458 -2.3408 4.7824
NCI-H1355 GDSC1; GDSC2 0.6711 6.6593 -3.5423 11.4583
NCI-H226 GDSC1; GDSC2 0.6902 2.4113 -1.5869 0.8597
NCI-H345 GDSC1; GDSC2 0.7157 1.6748 -1.3068 0.0851
NCI-H720 GDSC1 0.7234 1.8205 -1.354 0.1948
NCI-H1436 GDSC1; GDSC2 0.7442 3.0685 -1.8303 1.8666
NCI-H1092 GDSC1; GDSC2 0.7545 2.9529 -1.7766 1.6033
NCI-H2291 GDSC1; GDSC2 0.7576 4.7016 -2.5532 5.7184
NCI-H1793 GDSC1; GDSC2 0.7896 11.0161 -5.5897 20.6577
KNS-62 GDSC1; GDSC2 0.8 2.656 -1.6342 0.9511
COR-L23 GDSC1; GDSC2 0.8024 2.3662 -1.5211 0.5462
NCI-H2171 GDSC2 0.8084 2.7175 -1.6549 1.0253
NCI-H2066 GDSC1; GDSC2 0.8087 6.4059 -3.3256 9.9721
COR-L303 GDSC2 0.8111 16.6158 -8.3478 28.6857
Lu-134-A GDSC1; GDSC2 0.8118 3.9644 -2.1844 3.583
NCI-H2196 GDSC2 0.8437 2.8789 -1.7032 1.1904
NCI-H1915 GDSC1; GDSC2 0.8568 2.453 -1.5312 0.5449
NCI-H64 GDSC2 0.8884 13.0768 -6.5333 23.7021
NCI-H69 GDSC1; GDSC2 0.9032 4.8273 -2.5217 5.2818
NCI-H810 GDSC1; GDSC2 0.9073 5.2789 -2.7281 6.4291
SBC-5 GDSC1; GDSC2 0.9074 2.0772 -1.3764 0.1465
NCI-H1694 GDSC1; GDSC2 0.9175 2.5197 -1.5313 0.5095
NCI-H1944 GDSC1; GDSC2 0.9201 5.3833 -2.7686 6.6331
NCI-H2122 GDSC1; GDSC2 0.9215 2.6087 -1.563 0.6064
NCI-H2227 GDSC1; GDSC2 0.924 11.0583 -5.5105 20.04
NCI-H2029 GDSC1; GDSC2 0.9274 2.9409 -1.6895 1.0592
NCI-H522 GDSC1; GDSC2 0.9278 3.0903 -1.7493 1.303
NCI-H23 GDSC1; GDSC2 0.9313 3.0318 -1.724 1.1946
EBC-1 GDSC1; GDSC2 0.9374 3.5508 -1.9357 2.1373
NCI-H524 GDSC1; GDSC2 0.9441 3.048 -1.7246 1.1853
NCI-H1781 GDSC1; GDSC2 0.9507 2.5647 -1.5345 0.5005
NCI-H2810 GDSC1; GDSC2 0.9563 3.7113 -1.9943 2.3985
IST-SL2 GDSC1; GDSC2 0.9729 3.4174 -1.8618 1.7503
IA-LM GDSC1; GDSC2 0.9747 3.0477 -1.7104 1.101
NCI-H187 GDSC1 0.9821 2.5512 -1.5169 0.5397
COR-L279 GDSC1; GDSC2 0.9932 2.7524 -1.5875 0.6403
SW1271 GDSC1; GDSC2 0.9965 3.2524 -1.7826 1.3776
NCI-H1105 GDSC1; GDSC2 1.0104 2.665 -1.5476 0.5062
NCI-H2369 GDSC1; GDSC2 1.0184 7.2444 -3.5856 10.9381
NCI-H211 GDSC1 1.0313 4.0245 -2.0896 3.4468
COR-L321 GDSC1; GDSC2 1.0409 2.4653 -1.4631 0.2734
NCI-H1341 GDSC1; GDSC2 1.0413 2.9635 -1.6478 0.8125
NCI-H526 GDSC1; GDSC2 1.0424 2.5625 -1.4974 0.3535
NCI-H650 GDSC1; GDSC2 1.0467 4.8266 -2.4361 4.5703
BEN GDSC1; GDSC2 1.0478 2.0869 -1.3309 0.0621
NCI-H460 GDSC1; GDSC2 1.052 2.3693 -1.4252 0.1931
NCI-H2818 GDSC1; GDSC2 1.0569 11.8217 -5.7878 20.7786
Lu-165 GDSC1; GDSC2 1.0607 2.6062 -1.5061 0.3672
NCI-H2135 GDSC1; GDSC2 1.072 2.9023 -1.6113 0.6675
NCI-H292 GDSC1; GDSC2 1.0774 7.3583 -3.6003 10.892
PC-14 GDSC1; GDSC2 1.0777 3.0465 -1.6641 0.844
NCI-H2461 GDSC1; GDSC2 1.0801 4.7471 -2.381 4.2205
NCI-H838 GDSC1; GDSC2 1.0808 2.7284 -1.5428 0.4552
NCI-H520 GDSC1; GDSC2 1.0819 2.7417 -1.5472 0.4671
NCI-H146 GDSC1; GDSC2 1.0834 2.8979 -1.6049 0.6395
NCI-H835 GDSC1 1.0861 3.4177 -1.8073 1.7373
NCI-H1581 GDSC1; GDSC2 1.0922 3.0478 -1.6583 0.813
UMC-11 GDSC1; GDSC2 1.0931 2.9763 -1.6305 0.7172
NCI-H1568 GDSC1; GDSC2 1.0997 3.3404 -1.7699 1.2288
NCI-H2141 GDSC1; GDSC2 1.1031 2.8909 -1.5941 0.5937
NCI-H1435 GDSC1; GDSC2 1.1068 2.9937 -1.6314 0.711
Lu-99A GDSC1; GDSC2 1.108 3.7125 -1.9177 1.856
Lu-65 GDSC1; GDSC2 1.1236 2.9947 -1.6247 0.6783
EKVX GDSC1; GDSC2 1.1263 3.6846 -1.8972 1.7442
NCI-H2023 GDSC1; GDSC2 1.1303 3.2383 -1.7157 0.9923
NCI-H441 GDSC1; GDSC2 1.1304 8.7783 -4.2477 14.0675
NCI-H1876 GDSC1; GDSC2 1.1374 5.6489 -2.7571 6.1742
NCI-H1651 GDSC1; GDSC2 1.139 4.0225 -2.0323 2.3554
NCI-H1792 GDSC1; GDSC2 1.149 4.2988 -2.1454 2.8968
A-549 GDSC1; GDSC2 1.1511 5.5998 -2.7262 5.9807
NCI-H2170 GDSC1; GDSC2 1.1576 2.7303 -1.5135 0.3442
CPC-N GDSC1; GDSC2 1.1659 3.2159 -1.6914 0.8763
NCI-H1623 GDSC1; GDSC2 1.166 4.2403 -2.1112 2.705
DMS 53 GDSC1; GDSC2 1.1809 9.6808 -4.6501 15.8426
HCC78 GDSC1; GDSC2 1.1911 5.0595 -2.4572 4.4547
NCI-H1048 GDSC1; GDSC2 1.1935 2.752 -1.5076 0.316
SK-LU-1 GDSC1 1.1947 3.1176 -1.6415 0.8563
NCI-H1155 GDSC1; GDSC2 1.2052 2.6492 -1.4669 0.2262
EPLC-272H GDSC1; GDSC2 1.213 10.2361 -4.8976 16.8683
NCI-H727 GDSC1; GDSC2 1.219 3.3633 -1.7254 0.9594
HOP-62 GDSC1; GDSC2 1.2225 3.4869 -1.7723 1.1325
NCI-H661 GDSC1; GDSC2 1.2275 3.6484 -1.8343 1.3748
NCI-H3122 GDSC1; GDSC2 1.2278 3.9426 -1.9543 1.8909
NCI-H2731 GDSC1; GDSC2 1.2282 6.8567 -3.2628 8.777
Ms-1 GDSC1; GDSC2 1.234 3.2747 -1.6847 0.8051
NCI-H2081 GDSC1; GDSC2 1.2358 3.1087 -1.6212 0.5994
HCC15 GDSC1; GDSC2 1.2368 5.8311 -2.7804 6.1284
NCI-H847 GDSC1; GDSC2 1.2425 2.7384 -1.4844 0.249
Lu-139 GDSC1; GDSC2 1.2439 3.1558 -1.6355 0.6386
NCI-H82 GDSC1; GDSC2 1.2492 3.2234 -1.6588 0.709
CAL-12T GDSC1; GDSC2 1.2638 4.0474 -1.98 1.9676
HCC33 GDSC2 1.2668 8.8345 -4.1804 13.4448
LCLC-103H GDSC1; GDSC2 1.2691 2.5851 -1.4219 0.1345
Calu-3 GDSC1; GDSC2 1.2735 3.3083 -1.6808 0.7655
NCI-H1755 GDSC1; GDSC2 1.2736 3.6961 -1.8322 1.3244
COR-L32 GDSC1; GDSC2 1.2747 3.0212 -1.5733 0.4434
NCI-H748 GDSC2 1.2749 3.353 -1.6973 0.8199
NCI-H596 GDSC1; GDSC2 1.2751 9.8421 -4.6619 15.6882
COR-L95 GDSC1; GDSC2 1.2804 2.6862 -1.4525 0.1793
LB647-SCLC GDSC1; GDSC2 1.2958 3.214 -1.6361 0.6099
Calu-6 GDSC1; GDSC2 1.3058 4.0174 -1.9471 1.777
PaCa-3 GDSC1; GDSC2 1.3093 4.7734 -2.2652 3.2832
NCI-H2795 GDSC1; GDSC2 1.3196 3.6062 -1.7759 1.0675
NCI-H2087 GDSC1; GDSC2 1.3222 5.4741 -2.5678 4.8386
EMC-BAC-2 GDSC1; GDSC2 1.3227 3.741 -1.8276 1.2632
NCI-H510A GDSC2 1.3236 11.5586 -5.4639 18.9534
NCI-H1666 GDSC1; GDSC2 1.3239 3.8363 -1.8651 1.4126
LXF 289 GDSC1; GDSC2 1.3278 3.6315 -1.7822 1.0845
NCI-H1836 GDSC1; GDSC2 1.3293 3.0469 -1.5615 0.3888
HOP-92 GDSC1; GDSC2 1.3311 5.5293 -2.5875 4.9292
NCI-H1573 GDSC1; GDSC2 1.338 3.1174 -1.5836 0.4408
SBC-3 GDSC1; GDSC2 1.3384 3.0191 -1.548 0.3527
NCI-H1734 GDSC2 1.3487 3.2222 -1.6177 0.5279
NCI-H196 GDSC1; GDSC2 1.357 9.9505 -4.657 15.4876
SK-MES-1 GDSC1; GDSC2 1.36 3.8321 -1.8469 1.307
NCI-H1993 GDSC1; GDSC2 1.3685 3.4656 -1.7006 0.7691
COLO 668 GDSC1; GDSC2 1.3797 3.1432 -1.5768 0.405
NCI-H2172 GDSC1; GDSC2 1.384 2.7736 -1.4456 0.1447
NCI-H358 GDSC1; GDSC2 1.401 4.0202 -1.9033 1.4979
NCI-H446 GDSC1; GDSC2 1.4025 3.4064 -1.6643 0.6344
HCC827 GDSC1; GDSC2 1.4086 3.656 -1.7564 0.9305
NCI-H1563 GDSC1; GDSC2 1.412 3.0751 -1.5401 0.3075
NCI-H1770 GDSC1; GDSC2 1.4203 2.9726 -1.5011 0.2269
DMS 114 GDSC1; GDSC2 1.4221 3.4488 -1.6722 0.6469
NCI-H1437 GDSC1; GDSC2 1.4307 3.1901 -1.5741 0.3772
NCI-H1693 GDSC1; GDSC2 1.432 3.6502 -1.7442 0.8721
NCI-H1963 GDSC2 1.4377 3.3681 -1.6359 0.5334
VMRC-LCD GDSC1; GDSC2 1.4579 11.3358 -5.2589 17.8434
NCI-H1650 GDSC2 1.4607 5.5396 -2.5183 4.3661
NCI-H1688 GDSC1; GDSC2 1.4641 3.4081 -1.6401 0.5317
NCI-H2342 GDSC1; GDSC2 1.4663 3.3994 -1.6361 0.5196
A-427 GDSC1; GDSC2 1.4666 3.4586 -1.6578 0.5801
IST-SL1 GDSC1; GDSC2 1.4668 3.1451 -1.5444 0.2975
Lu-135 GDSC1; GDSC2 1.4679 3.4692 -1.6612 0.5891
RERF-LC-MS GDSC1; GDSC2 1.4778 3.0331 -1.5012 0.2112
NCI-H209 GDSC1; GDSC2 1.4865 5.8502 -2.642 4.9745
DMS 273 GDSC1; GDSC2 1.4875 3.0482 -1.503 0.2116
NCI-H2803 GDSC1; GDSC2 1.4934 3.2965 -1.5882 0.3853
NCI-H2228 GDSC2 1.5029 3.8033 -1.7726 0.9205
NCI-H2373 GDSC1; GDSC2 1.5219 3.4086 -1.6176 0.4451
NCI-H3255 GDSC1; GDSC2 1.5311 3.3593 -1.5963 0.3893
NCI-H2030 GDSC1; GDSC2 1.5363 3.6418 -1.6976 0.6585
NCI-H2085 GDSC1; GDSC2 1.5363 3.9708 -1.8228 1.0733
NCI-H2722 GDSC1; GDSC2 1.5427 3.7374 -1.7308 0.7567
COR-L88 GDSC1; GDSC2 1.5589 3.3687 -1.5892 0.3618
LK-2 GDSC1; GDSC2 1.5709 3.4571 -1.6163 0.4207
NCI-H1869 GDSC1 1.5835 3.5299 -1.6376 0.5835
ChaGo-K-1 GDSC1; GDSC2 1.6035 3.4111 -1.5874 0.3414
SW1573 GDSC1; GDSC2 1.6048 6.6113 -2.9164 6.2358
DMS 79 GDSC1; GDSC2 1.6163 3.3922 -1.576 0.3126
SBC-1 GDSC1; GDSC2 1.6185 3.2425 -1.523 0.2116
COR-L311 GDSC2 1.6216 3.1492 -1.4899 0.1589
NCI-H1299 GDSC1; GDSC2 1.636 8.459 -3.7544 10.5656
HCC366 GDSC1; GDSC2 1.636 3.6669 -1.667 0.5206
NCI-H1838 GDSC1; GDSC2 1.6525 3.585 -1.6309 0.4222
NCI-H290 GDSC1; GDSC2 1.6544 3.2444 -1.5108 0.183
NCI-H2347 GDSC1; GDSC2 1.6558 4.1581 -1.8434 1.0591
NCI-H513 GDSC1; GDSC2 1.6761 3.7788 -1.6921 0.5689
RERF-LC-Sq1 GDSC1; GDSC2 1.678 4.2844 -1.8827 1.1841
NCI-H2591 GDSC1; GDSC2 1.6962 4.0219 -1.7743 0.8005
NCI-H2869 GDSC1; GDSC2 1.7127 4.1101 -1.8008 0.8752
NCI-H2110 GDSC1; GDSC2 1.7275 3.8806 -1.7091 0.59
NCI-H2804 GDSC1; GDSC2 1.7492 5.0182 -2.1441 2.1817
LC-2/ad GDSC1; GDSC2 1.7635 3.8366 -1.6789 0.493
NCI-H2405 GDSC1; GDSC2 1.8224 10.2124 -4.4643 13.6352
NCI-H1648 GDSC1; GDSC2 1.851 3.9593 -1.6894 0.4811
NCI-H322M GDSC1; GDSC2 1.8529 8.4951 -3.6329 9.5378
EMC-BAC-1 GDSC1; GDSC2 1.8615 4.4674 -1.874 1.0207
LC-1/sq GDSC1; GDSC2 1.8669 4.2303 -1.7823 0.726
ABC-1 GDSC1; GDSC2 1.8815 4.2374 -1.7791 0.7083
NCI-H740 GDSC2 1.888 4.2623 -1.7857 0.7242
HCC44 GDSC1 1.9562 3.9814 -1.6573 0.4569
NCI-H2595 GDSC1; GDSC2 2.0068 10.9637 -4.6997 14.3264
LOU-NH91 GDSC1; GDSC2 2.1427 13.6603 -5.905 18.8743
COR-L105 GDSC1; GDSC2 2.238 4.7224 -1.8156 0.6295
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 1.3675 4.4007 -2.0758 2.2906
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-1 GDSC1; GDSC2 0.6181 2.4894 -1.6517 1.1913
OE19 GDSC1; GDSC2 0.6607 2.261 -1.5412 0.7118
T.T GDSC1; GDSC2 0.7574 3.6501 -2.0753 3.0847
TE-10 GDSC1; GDSC2 0.8871 3.309 -1.8593 1.8352
EC-GI-10 GDSC1; GDSC2 0.904 4.0417 -2.1666 3.3492
COLO 680N GDSC1; GDSC2 0.9128 2.648 -1.5817 0.6738
KYSE-450 GDSC1; GDSC2 0.9948 5.86 -2.9442 7.4748
KYSE-180 GDSC1; GDSC2 1.0512 3.4113 -1.8213 1.4889
TE-4 GDSC1; GDSC2 1.0923 3.0156 -1.6459 0.7698
TE-11 GDSC1; GDSC2 1.1225 3.2124 -1.709 0.9734
KYSE-150 GDSC1; GDSC2 1.1765 2.762 -1.5176 0.3463
KYSE-510 GDSC1; GDSC2 1.2667 3.0279 -1.579 0.4622
TE-15 GDSC1; GDSC2 1.3637 3.4833 -1.7094 0.8011
OE33 GDSC1; GDSC2 1.3962 3.9821 -1.8902 1.4488
KYSE-70 GDSC1; GDSC2 1.4475 3.3066 -1.6096 0.4581
TE-9 GDSC1; GDSC2 1.5112 2.9371 -1.4566 0.1345
KYSE-270 GDSC1; GDSC2 1.586 3.777 -1.7278 0.7215
TE-5 GDSC1; GDSC2 1.6143 3.4037 -1.5808 0.3233
TE-6 GDSC1; GDSC2 1.6336 3.4482 -1.5893 0.3347
KYSE-520 GDSC1; GDSC2 1.6542 4.0726 -1.8112 0.9485
KYSE-140 GDSC2 1.6585 12.5906 -5.7274 19.2297
OE21 GDSC1; GDSC2 1.7774 4.1989 -1.8074 0.8556
TE-8 GDSC1; GDSC2 1.8809 4.3956 -1.8386 0.8911
KYSE-410 GDSC2 4.6252 20.5695 -7.5339 19.5531
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OV56 GDSC1; GDSC2 0.5861 12.1091 -6.2842 23.6029
OVKATE GDSC1; GDSC2 0.6043 4.6799 -2.6402 6.5053
TOV-21G GDSC1; GDSC2 0.6552 7.7932 -4.1051 14.4395
A2780 GDSC1; GDSC2 0.71 2.9774 -1.8093 1.8073
Kuramochi GDSC1; GDSC2 0.7367 2.9601 -1.7885 1.6786
OVISE GDSC1; GDSC2 0.7983 2.7307 -1.6647 1.074
OAW42 GDSC1; GDSC2 0.8562 2.3908 -1.5082 0.475
SK-OV-3 GDSC1; GDSC2 0.9015 3.1448 -1.784 1.4788
OVCAR-8 GDSC1; GDSC2 0.9402 4.7831 -2.4792 4.9828
OV-90 GDSC1; GDSC2 0.9497 7.5757 -3.7918 12.1712
JHOS-2 GDSC1; GDSC2 0.9682 2.6634 -1.5643 0.5815
OVCAR-4 GDSC1; GDSC2 0.982 3.7948 -2.0167 2.4754
IGROV-1 GDSC1; GDSC2 1.0178 3.0484 -1.6913 0.9902
DOV13 GDSC1; GDSC2 1.1229 3.1435 -1.6821 0.8747
ES-2 GDSC1; GDSC2 1.1956 2.8069 -1.5264 0.3597
OVCAR-5 GDSC1; GDSC2 1.1967 3.1522 -1.6538 0.7265
EFO-21 GDSC1; GDSC2 1.2169 3.0538 -1.6084 0.5717
JHOS-4 GDSC1; GDSC2 1.3237 2.9974 -1.5458 0.3535
Caov-3 GDSC2 1.3845 3.4575 -1.6909 0.7274
RMG-I GDSC1; GDSC2 1.388 4.5282 -2.1191 2.4691
OVCAR-3 GDSC1; GDSC2 1.4382 3.3664 -1.6351 0.5309
TYK-nu GDSC1; GDSC2 1.5357 3.4372 -1.6227 0.4518
OVK18 GDSC1; GDSC2 1.5524 3.5368 -1.6524 0.5216
FU-OV-1 GDSC1; GDSC2 1.5995 8.0778 -3.5985 9.8373
EFO-27 GDSC1; GDSC2 1.6551 3.5387 -1.6133 0.3801
Caov-4 GDSC1; GDSC2 1.6691 5.9084 -2.5652 4.304
TOV-112D GDSC1; GDSC2 1.8473 3.6867 -1.5941 0.2754
OAW28 GDSC1; GDSC2 1.8685 4.0786 -1.7258 0.5666
OVTOKO GDSC1; GDSC2 2.0001 9.7384 -4.1221 11.6782
OC 314 GDSC1; GDSC2 5.4942 16.0916 -4.9329 9.6225
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-4 GDSC1; GDSC2 0.3937 2.8064 -1.9055 2.7289
SU.86.86 GDSC1; GDSC2 0.3943 2.6189 -1.8221 2.2856
MIA PaCa-2 GDSC1; GDSC2 0.4383 3.534 -2.2099 4.3459
Capan-1 GDSC2 0.6113 8.173 -4.3228 15.6164
Panc 04.03 GDSC2 0.7502 14.3318 -7.2606 26.1493
HuP-T4 GDSC2 0.8717 6.8724 -3.5067 10.8265
HPAC GDSC2 0.935 2.5515 -1.536 0.5137
KP-3 GDSC1; GDSC2 1.0387 5.8077 -2.8919 7.1005
DAN-G GDSC2 1.0833 4.8438 -2.4226 4.4387
SUIT-2 GDSC1; GDSC2 1.0891 3.0988 -1.6794 0.8904
PSN1 GDSC1; GDSC2 1.1104 2.8678 -1.5825 0.554
QGP-1 GDSC1; GDSC2 1.1378 2.9428 -1.5993 0.5893
Hs 766T GDSC1; GDSC2 1.1527 3.0077 -1.6176 0.6372
KP-2 GDSC1; GDSC2 1.1599 2.645 -1.4822 0.2722
Panc 10.05 GDSC1; GDSC2 1.1848 3.4177 -1.7619 1.1235
CFPAC-1 GDSC1; GDSC2 1.2342 3.2922 -1.6914 0.8277
PaTu 8988t GDSC1; GDSC2 1.2566 2.5802 -1.4246 0.1411
YAPC GDSC1; GDSC2 1.3657 2.6029 -1.3945 0.084
KP-1N GDSC1; GDSC2 1.4355 3.8438 -1.8176 1.1319
Panc 08.13 GDSC1; GDSC2 1.4879 3.5195 -1.6717 0.609
Panc 03.27 GDSC1; GDSC2 1.5303 3.0548 -1.4899 0.1792
HPAF-II GDSC1 1.5902 3.4086 -1.5915 0.4427
MZ-PC-1 GDSC1; GDSC2 1.5918 3.5245 -1.6325 0.4519
BxPC-3 GDSC1; GDSC2 1.6132 8.1152 -3.6073 9.8564
Capan-2 GDSC1; GDSC2 1.6944 4.1059 -1.8069 0.9071
HuP-T3 GDSC1; GDSC2 1.7132 3.9489 -1.74 0.6859
SW1990 GDSC1; GDSC2 1.719 10.2075 -4.5316 14.1542
Panc 02.03 GDSC1; GDSC2 1.7577 3.5998 -1.5966 0.3079
PL4 GDSC1; GDSC2 1.865 8.6263 -3.6865 9.7872
AsPC-1 GDSC1; GDSC2 1.9532 4.3886 -1.8062 0.7487
PaTu 8902 GDSC1; GDSC2 2.0411 20.0042 -9.0879 27.8049
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC2 0.7685 3.4099 -1.9639 2.4933
NCI-H2052 GDSC2 0.9218 3.2627 -1.8228 1.6296
NCI-H2452 GDSC1; GDSC2 1.1634 3.38 -1.7567 1.1214
MPP 89 GDSC1; GDSC2 1.2396 3.1417 -1.632 0.6302
NCI-H28 GDSC1; GDSC2 1.3432 4.1447 -1.9814 1.8892
IST-Mes1 GDSC1; GDSC2 1.3542 3.5075 -1.7227 0.8522
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2 -0.2951 3.0616 -2.4775 7.4796
NCI-H660 GDSC2 0.6987 2.3846 -1.5727 0.7985
VCaP GDSC1; GDSC2 0.8929 4.8181 -2.5238 5.3113
22Rv1 GDSC1; GDSC2 1.1625 3.4471 -1.7837 1.2284
PC-3 GDSC1; GDSC2 1.2959 3.8024 -1.8645 1.4355
DU145 GDSC1; GDSC2 1.7532 3.5702 -1.5879 0.292
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 1.0186 3.6441 -1.9338 2.0313
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-30 GDSC1; GDSC2 -0.0358 2.6837 -2.1136 4.6889
A2058 GDSC2 0.2647 3.0675 -2.1012 4.0374
CP50-MEL-B GDSC1; GDSC2 0.2726 3.6093 -2.35 5.4688
SK-MEL-28 GDSC1; GDSC2 0.3945 1.8247 -1.4883 0.7249
UACC-62 GDSC1; GDSC2 0.3945 2.3299 -1.6966 1.6508
M14 GDSC1 0.4518 3.5065 -2.189 5.221
G-mel GDSC1; GDSC2 0.5276 2.1181 -1.5443 0.8309
IGR-1 GDSC2 0.5519 9.0117 -4.7787 17.8804
WT2-iPS GDSC1; GDSC2 0.5546 2.214 -1.5702 0.9105
WM793 GDSC1; GDSC2 0.6003 4.9374 -2.7644 7.2286
COLO 792 GDSC1; GDSC2 0.6341 2.7537 -1.7535 1.6332
COLO 783 GDSC1; GDSC2 0.6463 2.2407 -1.5396 0.7167
RVH-421 GDSC1; GDSC2 0.6861 2.4539 -1.6057 0.9365
A-375 GDSC1; GDSC2 0.7045 4.1836 -2.3467 4.6498
IPC-298 GDSC1; GDSC2 0.7187 3.7 -2.1193 3.3775
SK-MEL-2 GDSC1 0.7666 1.8458 -1.3471 0.166
SH-4 GDSC1; GDSC2 0.7883 3.3014 -1.9067 2.1817
SK-MEL-5 GDSC1; GDSC2 0.8424 3.8461 -2.1146 3.1664
MMAc-SF GDSC1; GDSC2 0.8426 2.7631 -1.6574 1.0054
SK-MEL-31 GDSC1; GDSC2 0.8444 6.3852 -3.2916 9.7091
CHL-1 GDSC1; GDSC2 0.8575 2.7463 -1.644 0.9409
SK-MEL-3 GDSC1; GDSC2 0.8694 2.5029 -1.5448 0.5805
LB2518-MEL GDSC1; GDSC2 0.8738 2.5072 -1.5446 0.5769
UACC-257 GDSC1; GDSC2 0.9038 2.2939 -1.4539 0.3057
G-361 GDSC1; GDSC2 0.914 2.639 -1.5777 0.6596
RPMI-7951 GDSC2 0.9246 3.5362 -1.9361 2.1547
MeWo GDSC1; GDSC2 0.9319 2.8675 -1.6584 0.9352
LOX-IMVI GDSC1; GDSC2 1.0121 2.8689 -1.624 0.75
COLO 679 GDSC1; GDSC2 1.0313 2.8439 -1.6062 0.677
LB373-MEL-D GDSC1; GDSC2 1.0418 2.2457 -1.3863 0.1308
SK-MEL-1 GDSC1; GDSC2 1.0517 2.902 -1.6197 0.7087
VMRC-MELG GDSC1; GDSC2 1.0693 2.446 -1.4457 0.2272
A101D GDSC1; GDSC2 1.0695 8.0046 -3.9161 12.5514
WM35 GDSC1; GDSC2 1.0898 3.5572 -1.8625 1.6288
Hs 938.T GDSC1; GDSC2 1.1014 2.594 -1.4861 0.3024
COLO 829 GDSC1; GDSC2 1.1326 7.7693 -3.7599 11.6131
SK-MEL-24 GDSC1; GDSC2 1.141 2.7619 -1.5313 0.3956
IGR-37 GDSC1; GDSC2 1.1642 2.6226 -1.4727 0.2508
WM1552C GDSC1; GDSC2 1.2517 2.9735 -1.565 0.4322
Mel JuSo GDSC1; GDSC2 1.257 2.7115 -1.4697 0.216
MZ-MEL-7 GDSC1; GDSC2 1.2778 3.0674 -1.589 0.4841
IST-MEL1 GDSC1; GDSC2 1.3017 4.555 -2.175 2.8442
CP66-MEL GDSC1; GDSC2 1.3712 2.7293 -1.4351 0.1324
HT-144 GDSC1; GDSC2 1.3918 7.7261 -3.567 10.0773
HMV-II GDSC1; GDSC2 1.3987 3.9322 -1.8691 1.3614
A-388 GDSC1; GDSC2 1.4148 3.3089 -1.6233 0.51
GAK GDSC1; GDSC2 1.4337 3.0057 -1.5077 0.2353
DJM-1 GDSC1; GDSC2 1.5001 3.3729 -1.6132 0.4436
COLO 800 GDSC1; GDSC2 1.5722 3.7891 -1.7381 0.7618
Hs 940.T GDSC1; GDSC2 1.5889 3.5731 -1.6512 0.5012
Mel Ho GDSC1; GDSC2 1.5991 2.9595 -1.4338 0.0927
451Lu GDSC1; GDSC2 1.6004 3.4965 -1.6191 0.4153
MZ-MEL-2 GDSC1; GDSC2 1.6037 11.4934 -5.2323 17.4215
A-431 GDSC1; GDSC2 1.6903 3.4227 -1.5594 0.2566
WM278 GDSC1; GDSC2 3.8687 16.0128 -5.8718 15.5657
WM115 GDSC1; GDSC2 5.21 19.2475 -6.5352 15.6657
EquiPSC Line K2 GDSC1; GDSC2 0.8223 7.2573 -3.7263 12.1075
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 1.6593 3.2775 -1.5204 0.1971
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW684 GDSC1; GDSC2 0.552 2.7883 -1.8106 2.0111
TE 441.T GDSC2 0.5739 2.0323 -1.4904 0.5946
EW-8 GDSC1; GDSC2 0.6005 2.6683 -1.7345 1.5836
Rh18 GDSC1 0.8171 3.2845 -1.8845 2.5366
MES-SA GDSC1; GDSC2 0.8938 2.2592 -1.4453 0.2892
SW982 GDSC1; GDSC2 0.9211 2.8005 -1.637 0.8635
VA-ES-BJ GDSC1; GDSC2 0.9666 2.904 -1.6573 0.9033
SW872 GDSC1; GDSC2 0.9716 6.5458 -3.2834 9.4001
Hs 633.T GDSC1; GDSC2 0.9927 3.1139 -1.7286 1.1578
HT-1080 GDSC1; GDSC2 0.9984 2.5573 -1.5127 0.4135
RKN GDSC1; GDSC2 1.0297 2.3876 -1.4398 0.2281
SK-UT-1 GDSC1; GDSC2 1.0439 2.6977 -1.5462 0.4839
KYM-1 GDSC1; GDSC2 1.1608 2.6797 -1.4942 0.298
G-402 GDSC1; GDSC2 1.2434 3.617 -1.8145 1.2801
G-401 GDSC1; GDSC2 1.3732 3.8183 -1.8354 1.2506
Rh30 GDSC1; GDSC2 1.3988 6.3474 -2.9193 6.6009
SK-LMS-1 GDSC1; GDSC2 1.4906 3.6057 -1.7028 0.7005
Rh41 GDSC1; GDSC2 1.513 11.4566 -5.2785 17.8033
MFH-ino GDSC1; GDSC2 1.5852 3.8336 -1.7494 0.7897
A-204 GDSC1; GDSC2 1.7144 5.2017 -2.2375 2.642
GCT GDSC1; GDSC2 1.7521 3.6128 -1.6033 0.3233
RD GDSC1; GDSC2 1.7548 4.1924 -1.8144 0.8925
STS-0421 GDSC1; GDSC2 2.5119 4.7023 -1.7056 0.291
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
23132/87 GDSC1; GDSC2 0.0953 2.8124 -2.089 4.2834
RF-48 GDSC1; GDSC2 0.3364 3.2006 -2.1186 4.0075
SNU-16 GDSC1; GDSC2 0.4905 2.7981 -1.8478 2.2829
SCH GDSC1; GDSC2 0.5377 2.9131 -1.8724 2.3434
ECC10 GDSC1; GDSC2 0.6098 2.5939 -1.6988 1.4084
SNU-5 GDSC1; GDSC2 0.7171 2.314 -1.5372 0.6565
HGC-27 GDSC1; GDSC2 0.7537 3.8761 -2.1781 3.6396
TGBC11TKB GDSC1; GDSC2 0.8402 2.864 -1.6989 1.1755
GCIY GDSC2 0.8973 5.1113 -2.6565 6.0456
MKN45 GDSC1; GDSC2 0.9092 2.3543 -1.4737 0.3526
IM95 GDSC2 1.0117 7.8114 -3.8628 12.4034
KATO III GDSC1; GDSC2 1.0463 3.386 -1.8133 1.4596
ECC12 GDSC2 1.1271 7.2356 -3.5085 10.3007
RERF-GC-1B GDSC1; GDSC2 1.2153 4.8791 -2.3632 3.9205
HSC-39 GDSC1; GDSC2 1.2329 2.7303 -1.4851 0.2535
MKN28 GDSC2 1.2452 15.6574 -7.5396 25.8091
MKN7 GDSC1; GDSC2 1.2491 2.9691 -1.5644 0.4319
MKN1 GDSC1 1.2929 3.0178 -1.565 0.5151
NUGC-3 GDSC1; GDSC2 1.3336 3.5431 -1.7453 0.9455
OCUM-1 GDSC1; GDSC2 1.3355 3.844 -1.8629 1.3928
NCI-N87 GDSC1; GDSC2 1.3537 6.6917 -3.106 7.691
Fu97 GDSC1; GDSC2 1.4277 3.258 -1.5997 0.4415
Hs 746.T GDSC1; GDSC2 1.484 3.4181 -1.636 0.5105
SNU-1 GDSC1; GDSC2 1.5072 3.5373 -1.6705 0.5951
SK-GT-2 GDSC1; GDSC2 1.5843 4.093 -1.8493 1.1334
TMK-1 GDSC1; GDSC2 1.6616 3.5405 -1.6116 0.3736
NUGC-4 GDSC1; GDSC2 1.6692 12.6726 -5.7597 19.3265
AGS GDSC2 2.6929 18.2031 -7.7249 23.41
SNG-M GDSC1; GDSC2 1.2824 4.0577 -1.9751 1.9255
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C GDSC1; GDSC2 0.3566 4.0606 -2.5087 6.2325
IHH-4 GDSC1; GDSC2 0.5419 7.0227 -3.8102 13.1869
BHT-101 GDSC1; GDSC2 0.597 3.2623 -1.9933 2.8898
TT GDSC1; GDSC2 0.5994 2.6681 -1.735 1.587
8505C GDSC1; GDSC2 0.6049 3.1606 -1.9441 2.6193
WRO GDSC1; GDSC2 0.7816 2.885 -1.7352 1.3886
K5 GDSC1; GDSC2 0.8551 7.9019 -4.0157 13.5301
B-CPAP GDSC1; GDSC2 0.925 2.4032 -1.4853 0.3755
CAL-62 GDSC1; GDSC2 1.1199 6.2717 -3.0575 7.8637
CGTH-W-1 GDSC1; GDSC2 1.1354 10.4502 -5.0577 17.7265
ASH-3 GDSC1; GDSC2 1.2341 2.6618 -1.4608 0.2062
KMH-2 GDSC1; GDSC2 1.2392 3.0168 -1.5858 0.4945
TT2609-C02 GDSC1; GDSC2 1.2635 3.4673 -1.7464 1.0022
HTC-C3 GDSC1; GDSC2 1.2747 12.8616 -6.1386 21.5332
FTC-133 GDSC1; GDSC2 1.4733 3.0541 -1.5102 0.2284
ML-1 [Human leukemia] GDSC1; GDSC2 1.519 4.0603 -1.8654 1.245
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FaDu GDSC2 0.2565 2.1113 -1.6754 1.7241
BICR 22 GDSC1; GDSC2 0.6539 3.1797 -1.9257 2.4554
HSC-2 GDSC1; GDSC2 0.6785 3.1019 -1.8788 2.1852
PCI-15A GDSC1; GDSC2 0.8089 2.3371 -1.5074 0.4997
HSC-3 GDSC1; GDSC2 0.8173 2.5902 -1.6006 0.8096
OSC-20 GDSC1; GDSC2 0.8783 5.2724 -2.7433 6.5686
HO-1-u-1 GDSC1; GDSC2 0.937 4.4771 -2.3423 4.2384
PCI-30 GDSC1; GDSC2 0.9655 5.6356 -2.8577 7.0474
SCC-9 GDSC1; GDSC2 0.978 2.5875 -1.5319 0.478
JHU-022 GDSC1; GDSC2 0.9797 3.3396 -1.8263 1.5839
OSC-19 GDSC1; GDSC2 1.0308 2.8993 -1.6276 0.7495
UPCI-SCC-090 GDSC1; GDSC2 1.0648 4.2647 -2.176 3.1664
PCI-38 GDSC1 1.0996 3.7388 -1.9329 2.4069
SCC-25 GDSC1; GDSC2 1.1016 3.0457 -1.6535 0.7896
SKN-3 GDSC1; GDSC2 1.1324 4.5796 -2.2771 3.5927
SCC-15 GDSC1; GDSC2 1.1517 8.7109 -4.2002 13.7903
BICR 31 GDSC2 1.2254 2.9513 -1.5672 0.4506
SCC-4 GDSC1; GDSC2 1.2355 3.1675 -1.6434 0.6683
SAT [Human HNSCC] GDSC1; GDSC2 1.2426 4.8658 -2.3421 3.7705
CAL-27 GDSC1; GDSC2 1.2447 2.7865 -1.5005 0.2816
CAL-33 GDSC1; GDSC2 1.2665 3.3957 -1.7173 0.8953
SAS GDSC1; GDSC2 1.2823 3.8208 -1.8783 1.5055
BB49-HNC GDSC1 1.3011 3.8734 -1.8907 1.9161
JHU-029 GDSC1; GDSC2 1.317 3.5551 -1.7571 1.0004
Detroit 562 GDSC1; GDSC2 1.3238 3.3953 -1.6927 0.7719
LB771-HNC GDSC1; GDSC2 1.3662 3.6492 -1.7721 1.0178
NCI-H3118 GDSC1; GDSC2 1.3704 3.6931 -1.7874 1.0706
KON GDSC1; GDSC2 1.4072 3.4876 -1.6928 0.7197
HO-1-N-1 GDSC1; GDSC2 1.4783 3.4002 -1.6316 0.5017
KOSC-2 GDSC1; GDSC2 1.5009 3.6509 -1.7155 0.734
PCI-06A GDSC1; GDSC2 1.518 3.7659 -1.7519 0.8406
Ca9-22 GDSC1; GDSC2 1.5233 3.4889 -1.6464 0.5195
BHY GDSC1; GDSC2 1.5827 3.4755 -1.6183 0.4208
BB30-HNC GDSC1; GDSC2 1.6043 3.2053 -1.5152 0.2022
BICR 78 GDSC1; GDSC2 1.6635 9.3435 -4.1559 12.5015
BICR 10 GDSC1 1.7343 3.5181 -1.5766 0.3438
PE/CA-PJ15 GDSC1; GDSC2 1.7449 3.5805 -1.5946 0.308
JHU-011 GDSC2 1.8026 3.8797 -1.6793 0.4771
PCI-04B GDSC1; GDSC2 2.3317 4.4092 -1.6692 0.2757
DOK GDSC1; GDSC2 2.4654 11.9807 -4.8792 14.2118
HSC-4 GDSC1; GDSC2 4.8435 21.2852 -7.7297 19.7422
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC1; GDSC2 0.3391 2.5376 -1.8168 2.3385
647V GDSC1; GDSC2 0.4176 3.0086 -1.9825 3.1091
CAL-29 GDSC1; GDSC2 0.4722 2.7016 -1.8157 2.1436
RT-112 GDSC1; GDSC2 0.5093 8.1821 -4.402 16.242
TCCSUP GDSC1; GDSC2 0.6067 4.9404 -2.7616 7.1999
T24 GDSC1; GDSC2 0.6123 2.8065 -1.7869 1.8185
639V GDSC1; GDSC2 0.7088 2.0472 -1.4404 0.359
HT-1197 GDSC1; GDSC2 0.9571 3.5575 -1.9285 2.079
KU-19-19 GDSC1; GDSC2 1.0331 2.7292 -1.5623 0.5372
HT-1376 GDSC1; GDSC2 1.0531 7.6745 -3.7685 11.8264
5637 GDSC1; GDSC2 1.2355 3.4497 -1.7519 1.0443
RT-4 GDSC1; GDSC2 1.2998 3.3997 -1.7046 0.8277
SW780 GDSC1; GDSC2 1.3149 2.9102 -1.5181 0.2945
UM-UC-3 GDSC1; GDSC2 1.3782 2.8175 -1.4627 0.172
J82 GDSC1; GDSC2 1.6056 3.5 -1.6184 0.4114
SW1710 GDSC1; GDSC2 2.3075 17.4208 -7.6205 23.8662
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa GDSC1; GDSC2 0.2727 10.1824 -5.5692 21.8353
MS751 GDSC1; GDSC2 0.4166 3.2453 -2.0905 3.7093
NCC-IT GDSC2 0.4427 6.2066 -3.4832 11.6529
HEC-1 GDSC1; GDSC2 0.6866 5.461 -2.9561 8.1522
SW756 GDSC1; GDSC2 0.8412 3.6927 -2.0478 2.8211
SiHa GDSC1; GDSC2 0.8585 8.0473 -4.084 13.8666
PA-1 GDSC2 0.9151 2.9905 -1.7149 1.1723
C-4-I GDSC2 0.9249 2.4774 -1.5126 0.4506
SiSo GDSC1; GDSC2 0.9266 3.601 -1.9626 2.2809
HT-3 GDSC1; GDSC2 0.9291 3.4917 -1.9149 2.0479
SW954 GDSC1; GDSC2 0.984 3.1203 -1.7351 1.1921
JEG-3 GDSC1; GDSC2 0.9881 8.1367 -4.0363 13.3378
KGN GDSC1; GDSC2 0.9892 11.2075 -5.5357 19.9863
PWR-1E GDSC1; GDSC2 1.0058 2.9259 -1.6486 0.8415
DoTc2 4510 GDSC1; GDSC2 1.0246 3.4939 -1.8681 1.7225
NEC8 GDSC2 1.0647 9.8891 -4.8344 16.9257
JAR GDSC1; GDSC2 1.1024 2.6195 -1.4948 0.3222
PEO1 GDSC1; GDSC2 1.132 3.9073 -1.9872 2.1494
BPH-1 GDSC1; GDSC2 1.1764 4.2366 -2.1042 2.657
C-33 A GDSC1; GDSC2 1.23 3.7784 -1.8857 1.5877
OVMIU GDSC1; GDSC2 1.2307 4.3585 -2.128 2.7046
OVCA420 GDSC1; GDSC2 1.2571 3.1096 -1.6129 0.5625
HEY GDSC1; GDSC2 1.2885 3.21 -1.6376 0.6187
NT2-D1 GDSC1; GDSC2 1.3059 3.1883 -1.6224 0.5638
LB831-BLC GDSC1; GDSC2 1.3071 3.5729 -1.7684 1.0495
SW962 GDSC1; GDSC2 1.308 3.0065 -1.5551 0.3822
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 1.3242 3.039 -1.5606 0.3888
TC-YIK GDSC1 1.3386 3.1898 -1.6098 0.6364
OVCA433 GDSC1; GDSC2 1.3855 3.7399 -1.7991 1.1021
UWB1.289 GDSC1; GDSC2 1.4742 3.5618 -1.6931 0.6803
SKG-IIIa GDSC1; GDSC2 1.477 3.4822 -1.6623 0.5876
CAL-39 GDSC1; GDSC2 1.4849 3.3241 -1.6015 0.4209
ME-180 GDSC1; GDSC2 1.5454 4.4295 -2.001 1.7691
SKN GDSC1; GDSC2 1.5739 4.2121 -1.9007 1.3352
JHOS-3 GDSC1; GDSC2 1.5953 3.76 -1.7176 0.6852
Ca Ski GDSC1; GDSC2 1.6085 4.5039 -2.0014 1.7102
DSH1 GDSC1; GDSC2 1.6776 3.4823 -1.5849 0.3105
ACC-OV7 GDSC1; GDSC2 1.9855 4.3944 -1.7953 0.6996
OV17R GDSC1; GDSC2 2.4117 4.7589 -1.7621 0.4309
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun. 2012;3:1288.