Details of the Drug

General Information of Drug (ID: DMP3NH6)

• Drug Name: Pegtarviliase
• Synonyms: AGLE-177

Indication

Disease Entry	ICD 11	Status	REF
Homocystinuria	5C50.B	Phase 1/2	[1]

• Drug Type: Enzyme replacement
• Cross-matching ID: TTD ID: DL6W8B

References

• [1] ClinicalTrials.gov (NCT05154890) A Phase 1/2 Multiple Ascending-Dose Study in Subjects With Homocystinuria Due to Cystathionine beta-Synthase (CBS) Deficiency to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of ACN00177. U.S.National Institutes of Health.