Details of the Drug

General Information of Drug (ID: DMP9RBK)

Drug Name
WZ4003
Synonyms WZ-4003
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 497
Logarithm of the Partition Coefficient (xlogp) 4.1
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C25H29ClN6O3
IUPAC Name
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide
Canonical SMILES
CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC
InChI
InChI=1S/C25H29ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h5-9,14-16H,4,10-13H2,1-3H3,(H,28,33)(H,27,29,30)
InChIKey
SDGJBAUIGHSMRI-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
72200024
CAS Number
1214265-58-3
TTD ID
D00HLW
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
NUAK family SNF1-like kinase 2 (NUAK2) TTHVOTQ NUAK2_HUMAN Inhibitor [1]
Omphalocele kinase 1 (NUAK1) TT65FL0 NUAK1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
NUAK family SNF1-like kinase 1 (NUAK1) OTLLHJJQ NUAK1_HUMAN Drug Response [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 3.4253 5.0027 2.566 4.4938
CHSA8926 GDSC2 2.2251 7.5811 0.2211 22.4377
CAL-72 GDSC2 2.2278 4.725 1.5829 14.6638
EW-7 GDSC2 2.6327 3.5806 2.4861 7.7143
EW-11 GDSC2 2.6855 7.5187 0.6722 18.4082
NOS-1 [Human HNSCC] GDSC2 2.7971 4.1565 2.4143 7.4796
EW-22 GDSC2 2.9372 4.2675 2.4998 6.4433
ES8 GDSC2 2.9654 4.3298 2.4969 6.3616
SaOS-2 GDSC2 2.9989 5.7342 1.837 10.3795
EW-24 GDSC2 3.0573 4.2474 2.6237 5.2554
ES6 GDSC2 3.0673 6.6132 1.4596 12.5135
HuO9 GDSC2 3.1605 4.8472 2.4209 6.192
SK-ES-1 GDSC2 3.1833 5.1654 2.2822 6.997
EW-18 GDSC2 3.3951 5.6636 2.2114 6.8207
EW-1 GDSC2 3.4812 6.05 2.0882 7.3583
EW-16 GDSC2 3.4956 5.5287 2.3597 5.6053
HOS GDSC2 3.5421 5.0244 2.6465 3.6773
TC-71 GDSC2 3.5453 5.3504 2.4873 4.6699
ES5 GDSC2 3.6389 7.2802 1.6003 9.9797
EW-3 GDSC2 3.6445 8.0401 1.226 12.2447
HuO-3N1 GDSC2 3.6967 7.7661 1.4039 11.0274
ES7 GDSC2 3.7622 9.6321 0.5258 15.9243
A-673 GDSC2 3.998 8.8048 1.1215 11.9173
CADO-ES1 GDSC2 4.1023 6.4027 2.3733 4.0801
CAL-78 GDSC2 4.2075 8.4599 1.4484 9.4514
H-EMC-SS GDSC2 4.2442 7.4216 1.9805 6.149
MG-63 GDSC2 4.3189 8.1274 1.6908 7.7329
G-292 clone A141B1 GDSC2 4.4005 9.8767 0.8942 12.2094
CHSA0108 GDSC2 4.404 8.6374 1.5031 8.6621
MHH-ES-1 GDSC2 4.6549 7.552 2.1876 4.1034
U2OS GDSC2 4.666 8.2126 1.8855 5.834
NY GDSC2 5.4072 13.0626 0.061 14.2313
SK-PN-DW GDSC2 5.44 7.9636 2.4384 1.6922
ES4 GDSC2 5.5444 9.2279 1.9509 3.9509
U-CH2 GDSC2 5.7601 7.3537 2.8068 0.2481
EW-13 GDSC2 6.0056 7.7104 2.772 0.2413
EW-12 GDSC2 6.166 7.8789 2.7715 0.2011
CHSA0011 GDSC2 6.6423 8.9714 2.5643 0.4541
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 157 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 5.1172 7.6347 2.414 2.1788
AMO1 GDSC2 0.3175 6.8099 -1.291 36.6194
MOLM-13 GDSC2 0.7751 2.5993 0.7012 25.9359
Karpas-299 GDSC2 1.3288 3.1522 1.1907 20.7223
LAMA-84 GDSC2 1.6646 3.1331 1.561 17.1715
SR GDSC2 1.767 3.2052 1.6554 16.1875
A3/Kawakami GDSC2 1.8982 3.2945 1.7756 14.9322
L-540 GDSC2 1.9762 4.1576 1.5634 15.7879
BE-13 GDSC2 2.0682 4.4477 1.5401 15.5477
L-363 GDSC2 2.0941 4.1597 1.6871 14.5821
H9 GDSC2 2.2094 4.0268 1.8625 13.0857
MEG-01 GDSC2 2.2366 3.4777 2.0915 11.666
A4/Fukuda GDSC2 2.2419 3.2714 2.1566 11.2856
BC-1 GDSC2 2.3574 4.9131 1.6277 13.9004
ML-2 GDSC2 2.401 4.8317 1.7086 13.2479
ST486 GDSC2 2.4348 3.5495 2.2833 9.7191
DND-41 GDSC2 2.4626 4.865 1.7543 12.7406
KY821 GDSC2 2.5445 4.7294 1.8983 11.5606
ALL-PO GDSC2 2.548 7.9142 0.3527 20.6154
SU-DHL-10 GDSC2 2.568 4.1328 2.1927 9.6939
EoL-1 GDSC2 2.6013 3.6244 2.4362 8.1334
L-1236 GDSC2 2.613 4.7213 1.9696 10.8729
DEL GDSC2 2.6209 3.4282 2.5255 7.5444
SU-DHL-6 GDSC2 2.6709 3.7413 2.4651 7.6738
SCC-3 GDSC2 2.6952 3.5951 2.5479 7.0942
JVM-3 GDSC2 2.7022 10.3694 -0.7307 25.1932
GDM-1 GDSC2 2.749 5.7371 1.609 12.6208
MHH-CALL-2 GDSC2 2.7934 4.1809 2.3995 7.5837
SUP-M2 GDSC2 2.8152 3.7885 2.5968 6.3144
Namalwa GDSC2 2.8173 5.577 1.7504 11.5147
Loucy GDSC2 2.8249 5.2604 1.9126 10.4793
CML-T1 GDSC2 2.8265 3.65 2.6663 5.8607
GR-ST GDSC2 2.8574 4.4278 2.3463 7.675
U-698-M GDSC2 2.8579 4.3697 2.3745 7.4992
SU-DHL-5 GDSC2 2.8649 3.6451 2.7088 5.4548
MN-60 GDSC2 2.962 4.2101 2.5511 6.0385
Karpas-45 GDSC2 3.0899 4.5219 2.5191 5.8005
JVM-2 GDSC2 3.0917 6.139 1.7172 10.8375
IM-9 GDSC2 3.115 4.8996 2.3546 6.7539
RPMI-8226 GDSC2 3.1438 5.1224 2.2692 7.2019
KE-37 GDSC2 3.1606 4.5542 2.5666 5.2728
JURL-MK1 GDSC2 3.1689 5.2906 2.2073 7.5148
P32/ISH GDSC2 3.1742 4.2672 2.7212 4.2557
HAL-01 GDSC2 3.1752 5.8579 1.9297 9.2471
SUP-T1 GDSC2 3.1762 4.9248 2.3961 6.2998
PF-382 GDSC2 3.21 4.9165 2.4295 5.9843
Daudi GDSC2 3.2186 4.4943 2.6475 4.5801
MOLT-16 GDSC2 3.2201 4.9134 2.4399 5.8879
MLMA GDSC2 3.2222 8.2944 0.7521 16.2426
WSU-NHL GDSC2 3.2271 4.4016 2.7012 4.2147
K-562 GDSC2 3.2445 4.4404 2.6969 4.1882
Karpas-1106P GDSC2 3.308 5.3859 2.2783 6.6481
697 GDSC2 3.3082 5.6017 2.1706 7.3286
KOPN-8 GDSC2 3.3283 5.3122 2.3321 6.2486
P12-Ichikawa GDSC2 3.3338 5.6028 2.1913 7.1232
NALM-6 GDSC2 3.3408 5.6449 2.1761 7.1995
MOLT-13 GDSC2 3.3637 5.1945 2.4202 5.5889
CESS GDSC2 3.3793 5.6241 2.2183 6.822
DoHH2 GDSC2 3.3976 4.9218 2.5842 4.4555
P30/OHK GDSC2 3.4095 5.78 2.1651 7.0725
RPMI-6666 GDSC2 3.427 6.3152 1.9119 8.6203
OCI-AML-2 GDSC2 3.4515 5.7705 2.2038 6.7107
BL-41 GDSC2 3.4666 4.7419 2.7286 3.3563
DB GDSC2 3.4735 5.2384 2.4869 4.8628
ARH-77 GDSC2 3.4885 5.2561 2.4899 4.8033
SUP-HD1 GDSC2 3.5162 5.6614 2.3099 5.8646
SUP-B8 GDSC2 3.5426 5.5912 2.3655 5.4433
Ku812 GDSC2 3.5512 6.0933 2.1224 6.9524
Kasumi-1 GDSC2 3.5586 5.0509 2.6459 3.6398
CCRF-CEM GDSC2 3.5824 6.3933 1.9975 7.6539
MOLP-8 GDSC2 3.611 5.3687 2.5283 4.2443
Reh GDSC2 3.632 5.1998 2.6272 3.575
OCI-AML-3 GDSC2 3.6332 7.5145 1.4791 10.7411
EB2 GDSC2 3.6402 6.9534 1.7641 8.9595
Farage GDSC2 3.6536 5.3554 2.5666 3.9001
OCI-AML-5 GDSC2 3.6581 5.5804 2.4592 4.5595
HDLM-2 GDSC2 3.6586 5.4522 2.5227 4.1613
GA-10 GDSC2 3.6845 5.4046 2.5652 3.8345
SKM-1 GDSC2 3.6856 6.025 2.2602 5.7354
VAL GDSC2 3.7058 6.4529 2.0638 6.9141
RS4;11 GDSC2 3.7337 6.3117 2.1548 6.2734
SU-DHL-1 GDSC2 3.7426 10.3741 0.14 18.0016
BALL-1 GDSC2 3.7625 5.5794 2.5359 3.8324
MM1.S GDSC2 3.8251 7.0048 1.8811 7.7497
NCI-H929 GDSC2 3.8305 5.6655 2.5421 3.64
Jurkat GDSC2 3.8314 5.4801 2.6322 3.0891
OPM-2 GDSC2 3.8341 5.3286 2.7067 2.6338
TALL-1 [Human adult T-ALL] GDSC2 3.8649 6.7199 2.0515 6.5921
NOMO-1 GDSC2 3.889 5.4676 2.6769 2.6996
KM-H2 GDSC2 3.9132 6.5939 2.1487 5.8737
HEL GDSC2 3.9264 5.5622 2.6566 2.7451
Karpas-422 GDSC2 3.9938 7.379 1.8224 7.6947
BONNA-12 GDSC2 4.035 7.1003 1.989 6.572
Raji GDSC2 4.0773 15.7565 -2.2776 26.6532
KG-1 GDSC2 4.1625 5.9838 2.6092 2.5743
CTV-1 GDSC2 4.1676 8.7628 1.2701 10.6111
Jiyoye GDSC2 4.1704 10.211 0.5564 14.6582
WIL2 NS GDSC2 4.2089 5.933 2.6606 2.2036
RPMI-8866 GDSC2 4.2939 7.8266 1.8192 7.0147
U266B1 GDSC2 4.2957 10.1317 0.6906 13.6045
CA46 GDSC2 4.3222 6.7265 2.3636 3.7011
HC-1 GDSC2 4.336 6.6471 2.4093 3.4097
VL51 GDSC2 4.3541 6.5305 2.4745 3.0028
JeKo-1 GDSC2 4.362 6.1419 2.6553 1.9875
MOLM-16 GDSC2 4.377 6.0768 2.6926 1.7676
JSC-1 GDSC2 4.3773 6.6633 2.4274 3.2304
Hs 445 GDSC2 4.4389 6.4192 2.5753 2.3001
Ramos.2G6.4C10 GDSC2 4.4757 7.3821 2.154 4.6331
JJN-3 GDSC2 4.4919 6.9616 2.3601 3.4105
TUR GDSC2 4.5009 6.2165 2.6989 1.5641
HL-60 GDSC2 4.5394 6.3032 2.682 1.5981
SK-MM-2 GDSC2 4.5747 6.7167 2.5199 2.3892
NB4 GDSC2 4.5769 6.3526 2.6804 1.5571
LC4-1 GDSC2 4.5956 7.1308 2.3452 3.3149
SIG-M5 GDSC2 4.6508 5.5583 3.0274 0.1629
L-428 GDSC2 4.6784 7.0463 2.4319 2.7031
EM-2 GDSC2 4.7115 6.4574 2.7049 1.279
NK-92MI GDSC2 4.7215 6.4457 2.7147 1.2231
KMS-12-BM GDSC2 4.7283 6.5349 2.6808 1.3712
CTB-1 GDSC2 4.7428 7.1433 2.4251 2.6408
MC116 GDSC2 4.7433 6.1921 2.8278 0.7251
ME1 GDSC2 4.7463 6.2289 2.8146 0.7741
RC-K8 GDSC2 4.7786 6.6543 2.656 1.4291
HT GDSC2 4.795 6.2427 2.8309 0.6716
KCL-22 GDSC2 4.822 6.7356 2.6437 1.4365
OCI-Ly19 GDSC2 4.9127 6.7677 2.6749 1.1985
THP-1 GDSC2 5.0248 7.423 2.4564 2.0884
OCI-M1 GDSC2 5.051 6.2372 2.9368 0.2159
Karpas-231 GDSC2 5.1147 6.2221 2.9655 0.1422
HH [Human lymphoma] GDSC2 5.1507 7.8846 2.324 2.5837
SUP-B15 GDSC2 5.1734 6.8502 2.76 0.6486
OCI-Ly7 GDSC2 5.179 6.6758 2.8278 0.4336
MHH-PREB-1 GDSC2 5.2233 6.866 2.7749 0.5678
TK [Human B-cell lymphoma] GDSC2 5.2323 7.0427 2.7112 0.7761
NU-DUL-1 GDSC2 5.2804 6.9242 2.7766 0.5287
Karpas-620 GDSC2 5.2809 6.8257 2.8133 0.422
MHH-CALL-4 GDSC2 5.2839 7.5002 2.5531 1.3526
SU-DHL-8 GDSC2 5.3035 6.8121 2.8271 0.3741
SU-DHL-4 GDSC2 5.3052 6.6815 2.8747 0.2597
SU-DHL-16 GDSC2 5.3077 6.5527 2.9207 0.1684
CRO-AP2 GDSC2 5.4245 7.1199 2.7622 0.4917
ATN-1 GDSC2 5.4247 7.268 2.7069 0.6599
KMS-11 GDSC2 5.4903 7.5266 2.6359 0.8555
MOLT-4 GDSC2 5.5221 7.0436 2.8277 0.2838
RL GDSC2 5.5999 7.0553 2.8523 0.21
EJM GDSC2 5.6806 7.4446 2.7444 0.4159
ROS-50 GDSC2 5.7226 7.819 2.6228 0.7436
ALL-SIL GDSC2 5.7317 7.4117 2.7758 0.3214
LP-1 GDSC2 5.7444 7.2025 2.8534 0.1708
BC-3 GDSC2 5.7857 7.4584 2.7794 0.2945
Granta-519 GDSC2 5.868 7.7321 2.713 0.4133
RCH-ACV GDSC2 5.8709 7.4708 2.8063 0.2172
KMOE-2 GDSC2 5.902 7.8012 2.7012 0.4277
MY-M12 GDSC2 6.0719 8.0464 2.6782 0.4131
DG-75 GDSC2 6.2623 8.1961 2.6964 0.3073
QIMR-WIL GDSC2 6.3702 8.2477 2.7177 0.2387
PL-21 GDSC2 6.7191 8.8645 2.6302 0.2975
⏷ Show the Full List of 157 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 2.4921 3.5519 2.3444 9.1249
OACP4 C GDSC2 3.7154 6.6678 1.9646 7.5099
KYSE-50 GDSC2 3.7933 6.8995 1.9091 7.6561
KYAE-1 GDSC2 3.8125 7.0246 1.8618 7.9011
FLO-1 GDSC2 3.8911 9.7204 0.5837 15.2537
ESO-51 GDSC2 4.12 6.6553 2.2643 4.6995
SK-GT-4 GDSC2 4.5057 8.7555 1.5172 8.3484
TE-12 GDSC2 4.6086 8.0821 1.9098 5.806
OACM5.1 C GDSC2 4.7476 10.5929 0.7952 11.9319
HCE-4 GDSC2 5.2331 9.0399 1.855 4.9641
ESO-26 GDSC2 5.6353 7.7378 2.6169 0.8199
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 2.5128 3.655 2.3299 9.1177
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-14 GDSC2 2.0359 3.1483 1.9617 13.2912
Kelly GDSC2 2.1309 4.8123 1.4454 15.8592
SJNB-13 GDSC2 2.4554 3.9085 2.17 10.2811
NB69 GDSC2 2.6522 4.982 1.8842 11.2557
SK-N-DZ GDSC2 2.7693 4.5312 2.2119 8.8191
TGW GDSC2 2.9285 4.3791 2.438 6.8562
GOTO GDSC2 2.9747 4.9314 2.2123 8.1047
CHP-134 GDSC2 3.1671 4.5355 2.5817 5.157
NB(TU)1 GDSC2 3.2157 5.4218 2.1822 7.5302
CHP-212 GDSC2 3.295 6.4184 1.7512 10.0104
GI-ME-N GDSC2 3.6781 7.2681 1.6372 9.6456
SJNB-7 GDSC2 4.4578 6.3137 2.633 1.963
CHP-126 GDSC2 4.5739 6.5836 2.5784 2.0804
NH-12 GDSC2 4.6825 6.5553 2.6488 1.5786
SJNB-10 GDSC2 4.7615 10.018 1.0845 10.2848
SJNB-5 GDSC2 4.8191 6.7372 2.6416 1.4498
SK-N-MC-IXC GDSC2 4.8637 6.1074 2.9113 0.361
KP-N-RT-BM-1 GDSC2 5.0114 7.376 2.4695 2.041
SK-N-BE(2)-M17 GDSC2 5.0224 7.8494 2.2691 3.0509
SiMa GDSC2 5.1375 7.0339 2.6726 0.9972
LA-N-6 GDSC2 5.2264 7.0484 2.7065 0.7976
MHH-NB-11 GDSC2 5.2668 7.6193 2.4961 1.6185
KP-N-YN GDSC2 5.3059 7.8379 2.4245 1.9017
SJNB-6 GDSC2 5.3714 7.0481 2.7674 0.505
IMR-5 GDSC2 5.4063 11.4843 0.8199 10.3541
SK-N-AS GDSC2 5.4768 7.5443 2.6232 0.9107
KP-N-YS GDSC2 5.605 7.7957 2.5816 0.9651
SJNB-17 GDSC2 5.959 7.8717 2.6977 0.4125
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 3.7334 6.9815 1.8227 8.3482
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC2 2.2173 3.3793 2.1003 11.7045
CAL-85-1 GDSC2 2.7909 4.2509 2.3646 7.8054
Evsa-T GDSC2 2.7993 3.7719 2.5874 6.4341
HCC1500 GDSC2 2.8454 3.9179 2.5713 6.3483
HCC1806 GDSC2 3.0089 4.102 2.6479 5.2738
MDA-MB-415 GDSC2 3.5406 5.3103 2.5036 4.5792
HCC2157 GDSC2 3.7693 6.4961 2.0905 6.5858
HCC1569 GDSC2 3.7694 6.3395 2.1679 6.1029
JIMT-1 GDSC2 3.7731 6.0422 2.317 5.1647
HCC1937 GDSC2 3.9156 6.324 2.2823 5.0433
AU565 GDSC2 3.9344 7.3513 1.7921 8.027
MDA-MB-453 GDSC2 4.0428 7.1952 1.9482 6.8039
COLO 824 GDSC2 4.0596 6.2362 2.4242 3.8628
CAL-120 GDSC2 4.144 6.7182 2.2504 4.7326
BT-549 GDSC2 4.2497 6.4649 2.44 3.3926
HDQ-P1 GDSC2 4.407 7.1281 2.2293 4.3242
MDA-MB-361 GDSC2 4.4627 10.9527 0.4105 14.6887
BT-474 GDSC2 4.4901 6.5171 2.5608 2.2989
MDA-MB-157 GDSC2 4.5061 9.2812 1.2622 9.846
HCC70 GDSC2 4.5179 6.7711 2.4627 2.7904
MDA-MB-330 GDSC2 4.5704 9.0529 1.4184 8.7861
HCC1599 GDSC2 4.6675 6.5365 2.6491 1.5959
HCC1419 GDSC2 4.6931 7.8463 2.0748 4.6811
OCUB-M GDSC2 4.7901 6.8653 2.5724 1.8167
MCF-7 GDSC2 4.8811 8.1976 2.0284 4.605
BT-20 GDSC2 4.8933 13.8487 -0.6962 18.877
MFM-223 GDSC2 4.9188 7.1189 2.5311 1.8568
MDA-MB-231 GDSC2 4.9544 7.0888 2.5621 1.6653
MRK-nu-1 GDSC2 4.9932 6.5983 2.7794 0.7085
CAL-51 GDSC2 5.0881 6.7862 2.7479 0.7515
T-47D GDSC2 5.1349 7.8259 2.341 2.5193
CAMA-1 GDSC2 5.1838 7.1012 2.6668 0.9801
HCC2218 GDSC2 5.2002 7.6305 2.4584 1.8652
ZR-75-30 GDSC2 5.2114 9.5352 1.6133 6.3531
HCC1143 GDSC2 5.2126 8.3031 2.1746 3.2676
HCC38 GDSC2 5.2199 7.4832 2.5294 1.5198
Hs 578T GDSC2 5.2718 7.8563 2.3996 2.0585
UACC-893 GDSC2 5.3323 7.3835 2.6222 1.0289
MDA-MB-468 GDSC2 5.3509 9.1852 1.8589 4.7458
HCC1187 GDSC2 5.3617 7.2348 2.6929 0.7481
HCC1428 GDSC2 5.5192 7.9275 2.4907 1.3899
HCC1954 GDSC2 5.5999 7.3981 2.7297 0.4927
EFM-192A GDSC2 5.6044 7.4356 2.7177 0.524
MDA-MB-436 GDSC2 6.0708 7.6073 2.8304 0.1364
YMB-1-E GDSC2 6.3861 8.3887 2.6745 0.3117
EFM-19 GDSC2 6.4082 8.4546 2.6595 0.334
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC2 2.4401 3.3381 2.3551 9.2974
H4 GDSC2 2.9025 6.6807 1.2814 14.1261
8-MG-BA GDSC2 2.9859 3.8445 2.7462 4.7561
PFSK-1 GDSC2 2.9904 8.512 0.4457 18.6582
KINGS-1 GDSC2 3.143 7.1316 1.266 13.4639
AM-38 GDSC2 3.2824 5.9378 1.9809 8.6027
KS-1 [Human Krukenberg tumour] GDSC2 3.2954 5.9179 2.0018 8.4333
GI-1 GDSC2 3.4443 5.3911 2.3875 5.5702
SW1088 GDSC2 3.5642 6.175 2.0919 7.1089
Daoy GDSC2 3.6775 5.4136 2.5556 3.911
SF268 GDSC2 3.8305 5.8261 2.4642 4.1182
ONS-76 GDSC2 3.84 5.7091 2.5277 3.7073
CAS-1 GDSC2 3.9205 6.8132 2.0466 6.4881
D-392MG GDSC2 3.9422 8.8227 1.0699 12.3653
U-87MG ATCC GDSC2 3.9424 7.3148 1.8161 7.8595
DK-MG GDSC2 3.9751 5.7258 2.611 2.9189
YH-13 GDSC2 4.1505 6.1392 2.5295 3.058
LN-18 GDSC2 4.186 5.5952 2.799 1.4874
42-MG-BA GDSC2 4.2435 7.6931 1.8486 6.9503
GB-1 GDSC2 4.3308 7.7019 1.905 6.4155
T98G GDSC2 4.3533 7.419 2.0561 5.4601
D-263MG GDSC2 4.5446 10.3401 0.7723 12.5385
D-247MG GDSC2 4.5641 7.666 2.0773 4.9107
M059J GDSC2 4.9495 6.9221 2.6292 1.3618
GaMG GDSC2 5.1094 10.4717 1.1046 9.4157
NMC-G1 GDSC2 5.1215 6.6022 2.8319 0.4527
LN-229 GDSC2 5.1216 6.8919 2.7214 0.8229
D-542MG GDSC2 5.2115 6.7228 2.8235 0.4288
Hs 683 GDSC2 5.2221 6.5949 2.8741 0.2926
A-172 GDSC2 5.2311 8.1638 2.246 2.8709
U-118MG GDSC2 5.3356 7.3872 2.6222 1.0259
Becker GDSC2 5.43 7.4647 2.6337 0.908
SF295 GDSC2 5.4326 7.274 2.7079 0.6518
LN-405 GDSC2 5.4361 7.2649 2.7128 0.634
DBTRG-05MG GDSC2 5.492 7.5848 2.6142 0.9322
D-245MG GDSC2 5.5036 8.4633 2.2611 2.4401
YKG-1 GDSC2 5.5375 7.1117 2.8092 0.3192
SF126 GDSC2 5.5787 7.2076 2.7906 0.3462
KNS-81-FD GDSC2 5.6806 7.6746 2.6598 0.653
KALS-1 GDSC2 5.6861 8.1262 2.488 1.2527
U-251MG GDSC2 5.6931 7.2584 2.8155 0.2518
Onda 10 GDSC2 5.7679 7.7044 2.684 0.5347
KNS-42 GDSC2 5.7864 7.1643 2.8811 0.1225
D-336MG GDSC2 5.79 12.0371 0.8095 9.6425
SK-MG-1 GDSC2 5.9255 7.9533 2.6552 0.5357
D-423MG GDSC2 6.0333 8.5164 2.4884 0.9854
D-566MG GDSC2 6.2755 8.0021 2.7681 0.1817
D-502MG GDSC2 6.3053 8.395 2.6423 0.4057
Onda 11 GDSC2 6.3501 8.3438 2.677 0.318
SNB-75 GDSC2 6.3946 8.2628 2.7212 0.2268
SF539 GDSC2 7.3107 16.0226 -0.0921 11.2385
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC2 3.6851 6.9253 1.8132 8.5338
TGBC24TKB GDSC2 5.2385 7.8569 2.3822 2.182
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC2 3.516 6.1427 2.0698 7.3787
ESS-1 GDSC2 3.5417 6.0806 2.1212 6.9855
MFE-296 GDSC2 3.629 5.5078 2.4732 4.5443
KLE GDSC2 3.9918 7.8669 1.5807 9.1813
RL95-2 GDSC2 4.0367 7.5671 1.7615 7.9648
EN GDSC2 4.0859 6.194 2.4618 3.5842
MFE-319 GDSC2 4.8048 7.7398 2.1923 3.8154
AN3-CA GDSC2 5.5663 7.8291 2.5515 1.1073
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 GDSC2 1.4125 6.149 0.116 26.1211
KTCTL-195 GDSC2 2.2724 4.4203 1.7632 13.4148
A-704 GDSC2 3.1095 4.6343 2.4812 5.9744
SW13 GDSC2 3.3804 5.1758 2.4433 5.3956
HA7-RCC GDSC2 3.4507 5.3569 2.4096 5.4126
KMRC-20 GDSC2 3.771 9.1101 0.793 14.4196
A-498 GDSC2 3.7791 6.8609 1.9175 7.6397
KTCTL-140 GDSC2 4.0554 6.4981 2.2957 4.6483
NCC010 GDSC2 4.1409 6.971 2.1266 5.4898
769-P GDSC2 4.2311 6.6541 2.339 4.023
TK-10 GDSC2 4.2648 7.3992 2.0055 5.9528
ACHN GDSC2 4.2912 10.9141 0.3003 15.6985
OS-RC-2 GDSC2 4.2982 6.4919 2.4579 3.1984
LB996-RCC GDSC2 4.3004 11.2298 0.1509 16.4366
SW156 GDSC2 4.3053 6.6748 2.377 3.6546
RCC10RGB GDSC2 4.3075 7.8049 1.8392 6.8636
786-O GDSC2 4.5414 7.586 2.1003 4.8202
BFTC-909 GDSC2 4.6 23.4885 -5.717 32.9747
RXF 393L GDSC2 5.0369 8.9102 1.7949 5.6486
SN12C GDSC2 5.413 7.516 2.6061 1.024
VMRC-RCZ GDSC2 5.4508 7.6432 2.5729 1.1206
Caki-1 GDSC2 5.5313 8.1538 2.4043 1.7471
UO-31 GDSC2 5.5767 7.5641 2.6583 0.7211
NCC021 GDSC2 5.5834 7.4121 2.718 0.5342
KTCTL-13 GDSC2 5.7981 7.4345 2.7924 0.2642
VMRC-RCW GDSC2 5.9656 7.4761 2.8381 0.1459
LB1047-RCC GDSC2 5.9978 8.053 2.6472 0.5224
LB2241-RCC GDSC2 6.0265 7.9788 2.6851 0.415
KTCTL-26A GDSC2 6.0345 8.1024 2.6436 0.5148
BB65-RCC GDSC2 6.0438 7.9752 2.693 0.39
KTCTL-1M GDSC2 6.0914 8.0803 2.6735 0.4165
KTCTL-21 GDSC2 7.0092 9.446 2.5334 0.3934
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 15 GDSC2 1.9949 3.7578 1.735 14.7254
LoVo GDSC2 2.8932 4.7338 2.2332 8.2501
HT-55 GDSC2 3.1273 4.2532 2.6856 4.6328
KM12 GDSC2 3.1335 5.7107 1.9671 9.1388
HT-29 GDSC2 3.3243 5.214 2.3779 5.97
CL-11 GDSC2 3.4068 6.2098 1.9481 8.4497
LS513 GDSC2 3.4559 5.0444 2.5697 4.3875
SW626 GDSC2 3.5252 5.3547 2.4696 4.8335
NCI-H747 GDSC2 3.559 5.9163 2.2166 6.3383
NCI-H716 GDSC2 3.6126 5.289 2.5689 3.9864
HCT 116 GDSC2 3.7154 5.4038 2.5879 3.6207
SNU-175 GDSC2 3.8664 6.2859 2.2656 5.261
LS180 GDSC2 3.901 5.7181 2.5653 3.3456
LS411N GDSC2 4.0826 5.7288 2.6779 2.3245
SNU-C5 GDSC2 4.0877 6.6784 2.2311 4.9709
C2BBe1 GDSC2 4.1174 12.648 -0.6959 20.8541
GP5d GDSC2 4.1382 6.0844 2.5473 2.9774
MDST8 GDSC2 4.2005 5.9031 2.6692 2.1694
HCC2998 GDSC2 4.397 6.5841 2.4759 2.92
SNU-C2B GDSC2 4.5086 7.7958 1.9798 5.5946
SW1463 GDSC2 4.5788 9.2814 1.3136 9.38
RKO GDSC2 4.5904 8.6279 1.6372 7.4535
SNU-61 GDSC2 4.6355 8.1476 1.8964 5.8311
DiFi GDSC2 4.7077 7.5414 2.2247 3.7998
SNU-283 GDSC2 4.7181 6.6362 2.6328 1.6121
COLO205 GDSC2 4.7223 6.9849 2.4838 2.3608
SW620 GDSC2 4.7747 7.087 2.4679 2.3685
SNU-C1 GDSC2 4.9901 8.1363 2.1219 3.8967
SW1116 GDSC2 5.0243 13.4287 -0.3924 17.2312
SNU-1040 GDSC2 5.1048 6.5682 2.8378 0.4445
SW48 GDSC2 5.1417 7.1243 2.6384 1.1313
SNU-81 GDSC2 5.1477 7.1585 2.6274 1.1711
SW948 GDSC2 5.1878 6.4891 2.8989 0.2492
SK-CO-1 GDSC2 5.1922 6.7871 2.7917 0.5338
SW1417 GDSC2 5.1939 7.9142 2.3343 2.4745
CaR-1 GDSC2 5.1957 7.1992 2.6333 1.1029
HT115 GDSC2 5.3182 6.6809 2.8797 0.2442
NCI-H508 GDSC2 5.408 7.232 2.7135 0.6491
CCK-81 GDSC2 5.6091 7.7092 2.6167 0.8384
RCM-1 [Human ESC] GDSC2 5.648 7.0834 2.8599 0.1838
COLO 678 GDSC2 5.6626 8.2511 2.4272 1.5188
LS123 GDSC2 5.6994 7.4213 2.7601 0.3697
CW-2 GDSC2 5.7398 7.7869 2.642 0.673
LS1034 GDSC2 5.8813 7.3547 2.8498 0.1464
SW837 GDSC2 5.9546 7.8268 2.7121 0.3806
SNU-407 GDSC2 5.9986 8.2567 2.5723 0.7356
COLO 320HSR GDSC2 6.0919 7.7404 2.7926 0.1854
T84 GDSC2 6.2104 8.2671 2.652 0.4196
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 4.5362 6.3696 2.6515 1.756
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-423 GDSC2 2.4066 4.5625 1.837 12.4514
SNU-449 GDSC2 2.5969 4.9055 1.867 11.56
Hep 3B2.1-7 GDSC2 3.2462 5.6362 2.1011 7.9514
Hep-G2/C3A GDSC2 3.5047 6.5729 1.8462 8.8158
HLE GDSC2 3.6928 5.976 2.2899 5.5316
JHH-2 GDSC2 3.8128 5.8309 2.4493 4.2509
SNU-387 GDSC2 3.9497 13.3422 -1.1751 23.2431
JHH-6 GDSC2 4.0158 9.0275 1.0248 12.4348
JHH-7 GDSC2 4.0921 7.3948 1.8863 7.0685
HuH-1 GDSC2 4.292 7.6597 1.8986 6.5395
SK-HEP-1 GDSC2 4.46 7.9788 1.8601 6.4072
SNU-398 GDSC2 4.7424 7.4408 2.2913 3.369
JHH-1 GDSC2 5.0321 6.1717 2.9529 0.1891
Huh-7 GDSC2 5.1808 7.2983 2.5863 1.3121
JHH-4 GDSC2 6.7398 13.7857 0.5896 9.0329
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 166 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H209 GDSC2 1.9266 4.6851 1.2917 17.5725
NCI-H82 GDSC2 2.0886 3.0512 2.039 12.6323
NCI-H211 GDSC2 2.2631 3.6149 2.0749 11.6416
NCI-H322M GDSC2 2.3562 9.0039 -0.3592 24.763
NCI-H2795 GDSC2 2.3594 4.1729 1.9597 11.9048
SBC-3 GDSC2 2.428 3.8138 2.1787 10.3443
NCI-H2731 GDSC2 2.4918 4.3306 2.0274 10.9796
NCI-H524 GDSC2 2.5252 3.4238 2.4226 8.5424
Ms-1 GDSC2 2.5781 3.5456 2.4397 8.2133
HCC78 GDSC2 2.6501 6.2887 1.2472 15.1687
Lu-65 GDSC2 2.6502 3.9045 2.376 8.28
Lu-139 GDSC2 2.7051 3.7641 2.492 7.3765
NCI-H2122 GDSC2 2.8767 4.6171 2.274 8.054
Calu-3 GDSC2 2.9199 4.4123 2.4138 7.0361
HCC827 GDSC2 2.9266 3.968 2.6303 5.6822
CPC-N GDSC2 2.9276 3.9583 2.6357 5.6459
NCI-H2023 GDSC2 2.9663 4.7925 2.2726 7.7554
A-549 GDSC2 3.0071 5.7404 1.8413 10.3268
NCI-H1792 GDSC2 3.0087 4.5944 2.409 6.7604
DMS 273 GDSC2 3.0131 4.6305 2.3953 6.8312
NCI-H2461 GDSC2 3.0714 4.8134 2.3583 6.8709
COR-L105 GDSC2 3.1523 5.3915 2.1426 7.9741
NCI-H1755 GDSC2 3.1606 9.9952 -0.1501 21.1488
NCI-H650 GDSC2 3.161 4.9768 2.3568 6.5949
LCLC-103H GDSC2 3.1779 6.0251 1.8485 9.7498
NCI-H1666 GDSC2 3.2149 5.3882 2.1983 7.4309
HARA [Human squamous cell lung carcinoma] GDSC2 3.2377 4.5039 2.6594 4.4465
SK-MES-1 GDSC2 3.2523 5.2731 2.2878 6.7529
LXF 289 GDSC2 3.2669 9.1761 0.3489 18.3151
NCI-H810 GDSC2 3.3135 4.9225 2.5146 5.1359
COR-L311 GDSC2 3.3286 5.4167 2.2801 6.5767
NCI-H1299 GDSC2 3.3442 6.8061 1.5984 10.8201
EMC-BAC-2 GDSC2 3.3646 5.2918 2.3723 5.8892
LK-2 GDSC2 3.3722 5.4742 2.2874 6.405
EPLC-272H GDSC2 3.3985 5.6565 2.2178 6.7705
SK-LU-1 GDSC2 3.4323 5.6595 2.2438 6.5114
KNS-62 GDSC2 3.5265 5.5511 2.3729 5.4397
EBC-1 GDSC2 3.6006 6.9257 1.7467 9.1752
NCI-H1993 GDSC2 3.6092 7.1606 1.6365 9.8365
NCI-H2228 GDSC2 3.6096 7.602 1.4167 11.1877
SHP-77 GDSC2 3.6649 5.3033 2.6005 3.662
NCI-H358 GDSC2 3.7012 6.9912 1.793 8.6174
HCC44 GDSC2 3.7092 7.226 1.6825 9.2821
NCI-H1355 GDSC2 3.7427 11.4473 -0.3956 20.5681
Lu-135 GDSC2 3.7446 5.5874 2.5192 3.9775
NCI-H1915 GDSC2 3.7456 6.8488 1.8979 7.848
LOU-NH91 GDSC2 3.7832 6.5997 2.0498 6.8052
NCI-H526 GDSC2 3.7954 7.1948 1.7645 8.5488
NCI-H1975 GDSC2 3.8025 6.6835 2.0229 6.9246
UMC-11 GDSC2 3.8104 5.7715 2.4765 4.0887
NCI-H2087 GDSC2 3.8223 6.3343 2.2097 5.7128
NCI-H2170 GDSC2 3.8307 5.8085 2.4729 4.064
Lu-99A GDSC2 3.8471 6.0403 2.3717 4.6506
IST-SL2 GDSC2 3.8789 6.4844 2.1774 5.7774
NCI-H446 GDSC2 3.898 5.7467 2.5495 3.4477
NCI-H2141 GDSC2 3.9021 5.758 2.5469 3.4545
IA-LM GDSC2 3.9638 8.4803 1.2561 11.2101
NCI-H1869 GDSC2 4.0018 9.808 0.6266 14.7205
NCI-H1581 GDSC2 4.0052 7.5819 1.7311 8.2281
RERF-LC-Sq1 GDSC2 4.0437 12.8339 -0.8468 21.6843
NCI-H2227 GDSC2 4.0452 12.1198 -0.4897 20.1519
NCI-H2373 GDSC2 4.0773 7.219 1.9614 6.6427
NCI-H3255 GDSC2 4.0821 6.2205 2.4467 3.6818
LCLC-97TM1 GDSC2 4.0824 6.5588 2.285 4.6547
PC-14 GDSC2 4.1509 7.3839 1.9335 6.6442
HOP-92 GDSC2 4.1645 12.9012 -0.7849 21.1036
BEN GDSC2 4.165 5.3111 2.9109 0.9487
NCI-H2803 GDSC2 4.1788 6.9199 2.1772 5.1003
NCI-H596 GDSC2 4.1812 6.5058 2.3765 3.8999
NCI-H1563 GDSC2 4.26 7.8862 1.7665 7.4102
NCI-H1623 GDSC2 4.2701 7.3512 2.0322 5.7801
NCI-H647 GDSC2 4.2779 6.6522 2.3701 3.7474
NCI-H1651 GDSC2 4.3354 8.7968 1.3763 9.5753
NCI-H2818 GDSC2 4.3574 7.5487 1.9968 5.8069
NCI-H250 GDSC2 4.3582 7.004 2.2563 4.2609
NCI-H1568 GDSC2 4.3803 9.8694 0.8829 12.3226
NCI-H2804 GDSC2 4.4046 6.6683 2.4418 3.0998
COR-L23 GDSC2 4.4322 6.444 2.5604 2.3922
VMRC-LCD GDSC2 4.4663 8.4576 1.6339 7.743
NCI-H345 GDSC2 4.4689 5.5112 2.9724 0.4064
NCI-H2810 GDSC2 4.4858 7.1401 2.2737 3.917
NCI-H522 GDSC2 4.5031 8.744 1.521 8.3322
Calu-6 GDSC2 4.5465 6.8732 2.4333 2.9063
DMS 79 GDSC2 4.5491 7.0155 2.37 3.2551
SBC-5 GDSC2 4.5657 5.4819 3.0225 0.2068
HOP-62 GDSC2 4.5783 7.6044 2.1153 4.6619
RERF-LC-KJ GDSC2 4.6213 7.6415 2.1251 4.5246
NCI-H2171 GDSC2 4.6219 6.2412 2.7505 1.1699
NCI-H2591 GDSC2 4.6256 11.6838 0.1715 15.5107
NCI-H23 GDSC2 4.6434 6.9615 2.4497 2.661
NCI-H1105 GDSC2 4.6638 6.8145 2.5265 2.2223
HCC366 GDSC2 4.6756 7.2301 2.3475 3.1686
COR-L321 GDSC2 4.688 6.5035 2.6736 1.4524
SW1271 GDSC2 4.7107 7.2769 2.3469 3.1146
NCI-H2722 GDSC2 4.7289 7.0826 2.4443 2.5597
NCI-H441 GDSC2 4.7361 13.2529 -0.5199 18.4975
NCI-H513 GDSC2 4.8086 6.8824 2.5748 1.7815
NCI-H1876 GDSC2 4.8102 6.6798 2.6612 1.3693
NCI-H2869 GDSC2 4.821 7.0148 2.5244 2.0154
NCI-H2081 GDSC2 4.8425 6.9359 2.5696 1.7645
NCI-H2369 GDSC2 4.8516 6.4687 2.7671 0.8707
NCI-H2110 GDSC2 4.8788 7.2744 2.4428 2.3513
NCI-H2444 GDSC2 4.8859 5.9227 2.9864 0.1691
NCI-H1944 GDSC2 4.9137 8.9943 1.6773 6.5554
COR-L32 GDSC2 4.9296 7.9694 2.1619 3.7757
NCI-H1092 GDSC2 4.9339 6.7961 2.6735 1.1833
NCI-H1781 GDSC2 5.0099 14.5335 -0.9468 19.6384
NCI-H196 GDSC2 5.0334 6.6617 2.7723 0.7043
NCI-H1836 GDSC2 5.0623 6.8733 2.7022 0.9451
IST-SL1 GDSC2 5.0651 7.2626 2.5448 1.6186
NCI-H661 GDSC2 5.0964 7.0755 2.6369 1.1799
NCI-H460 GDSC2 5.1135 6.5214 2.8585 0.3811
COR-L303 GDSC2 5.1173 6.7652 2.7686 0.6573
NCI-H1693 GDSC2 5.1546 6.7697 2.7827 0.5857
NCI-H1048 GDSC2 5.1622 6.933 2.7232 0.7851
NCI-H720 GDSC2 5.1826 6.7375 2.8063 0.4946
NCI-H748 GDSC2 5.1977 7.1676 2.6468 1.047
NCI-H1793 GDSC2 5.2041 6.887 2.7589 0.6318
NCI-H1694 GDSC2 5.2662 7.0411 2.7264 0.6992
NCI-H1436 GDSC2 5.28 7.1367 2.6956 0.797
COLO 668 GDSC2 5.2803 7.0136 2.7428 0.6351
Lu-165 GDSC2 5.3343 7.1122 2.7281 0.6487
NCI-H838 GDSC2 5.3651 6.9235 2.8107 0.3884
A-427 GDSC2 5.4092 9.3282 1.8284 4.8163
LB647-SCLC GDSC2 5.41 7.214 2.7212 0.6236
NCI-H2029 GDSC2 5.4454 6.8585 2.8644 0.2334
HCC33 GDSC2 5.4459 6.803 2.884 0.1958
DMS 53 GDSC2 5.4576 7.5157 2.6259 0.9154
ChaGo-K-1 GDSC2 5.4594 7.5188 2.6255 0.9155
NCI-H740 GDSC2 5.481 7.8243 2.5145 1.3274
NCI-H2135 GDSC2 5.4827 7.0673 2.8042 0.353
NCI-H290 GDSC2 5.5248 7.3041 2.7344 0.5183
NCI-H1435 GDSC2 5.5295 7.0385 2.8322 0.2715
RERF-LC-MS GDSC2 5.5328 7.4073 2.6992 0.6185
SBC-1 GDSC2 5.5403 6.9037 2.8832 0.1721
NCI-H1770 GDSC2 5.558 6.9276 2.8813 0.1707
EKVX GDSC2 5.5874 8.842 2.1429 2.9112
NCI-H146 GDSC2 5.5993 7.0277 2.8616 0.1935
NCI-H2291 GDSC2 5.6084 7.888 2.547 1.0902
NCI-H2172 GDSC2 5.6137 7.418 2.7279 0.4907
NCI-H2030 GDSC2 5.6437 7.4946 2.7117 0.5207
NCI-H1963 GDSC2 5.6456 7.8461 2.5797 0.9418
NCI-H2196 GDSC2 5.6538 7.3117 2.782 0.3368
HCC15 GDSC2 5.6552 13.1609 0.1849 13.0913
NCI-H841 GDSC2 5.6697 7.1396 2.8483 0.1979
NCI-H3122 GDSC2 5.6751 13.5002 0.0353 13.7738
NCI-H292 GDSC2 5.7051 7.289 2.8092 0.2605
NCI-H510A GDSC2 5.711 7.4751 2.7452 0.4009
DMS 114 GDSC2 5.7387 7.3497 2.8002 0.2675
Lu-134-A GDSC2 5.8242 17.8309 -1.9676 21.5471
NCI-H2595 GDSC2 5.8456 7.7047 2.7143 0.4195
CAL-12T GDSC2 5.8542 7.9959 2.6107 0.7022
LC-2/ad GDSC2 5.8755 7.8094 2.688 0.4725
NCI-H2085 GDSC2 5.8978 9.3508 2.087 2.7931
NCI-H1437 GDSC2 5.9138 8.8857 2.2884 1.8621
SW1573 GDSC2 5.9353 8.4007 2.4908 1.0462
NCI-H520 GDSC2 5.964 7.616 2.7897 0.2214
NCI-H1155 GDSC2 5.9832 7.3441 2.8884 0.0841
NCI-H727 GDSC2 6.0508 8.1553 2.6307 0.5409
NCI-H1734 GDSC2 6.1068 8.0001 2.7078 0.3348
ABC-1 GDSC2 6.1325 8.0169 2.7114 0.3188
NCI-H2405 GDSC2 6.1797 8.0557 2.7152 0.2963
NCI-H1650 GDSC2 6.1849 8.3841 2.5999 0.5592
NCI-H226 GDSC2 6.464 20.0959 -2.6125 22.2577
EMC-BAC-1 GDSC2 6.4995 8.9915 2.5019 0.6707
LC-1/sq GDSC2 6.73 8.8792 2.629 0.2966
⏷ Show the Full List of 166 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 4.0486 7.9204 1.5966 8.9435
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-140 GDSC2 2.3938 4.1886 1.9887 11.5961
OE33 GDSC2 2.7324 4.6225 2.1328 9.4381
KYSE-450 GDSC2 3.2429 4.286 2.7726 3.715
KYSE-510 GDSC2 3.5954 5.763 2.3211 5.5846
COLO 680N GDSC2 3.621 5.3796 2.5305 4.2057
KYSE-180 GDSC2 3.6478 5.6429 2.4206 4.8266
EC-GI-10 GDSC2 3.6716 5.2573 2.6279 3.4762
OE19 GDSC2 3.7781 5.4918 2.5897 3.4659
OE21 GDSC2 4.0131 7.8021 1.6285 8.8362
TE-15 GDSC2 4.0736 6.3749 2.3673 4.1759
KYSE-410 GDSC2 4.091 8.4422 1.3711 10.2003
KYSE-520 GDSC2 4.2374 6.3711 2.476 3.2059
TE-9 GDSC2 4.2507 6.2908 2.5216 2.9178
TE-8 GDSC2 4.2656 8.6923 1.3768 9.7383
KYSE-270 GDSC2 4.5311 7.052 2.3424 3.4422
TE-5 GDSC2 4.5505 8.3705 1.7336 6.9676
TE-4 GDSC2 4.7025 6.6288 2.6279 1.6555
TE-1 GDSC2 5.0573 11.1877 0.7246 11.6131
KYSE-70 GDSC2 5.0782 10.6902 0.9788 10.1808
TE-6 GDSC2 5.1972 7.0921 2.6765 0.9318
TE-11 GDSC2 6.1097 7.8392 2.765 0.2255
TE-10 GDSC2 6.2842 8.1199 2.7309 0.2384
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TOV-21G GDSC2 2.8325 4.6686 2.2071 8.6232
A2780 GDSC2 3.001 5.5978 1.9066 9.9362
IGROV-1 GDSC2 3.1375 6.5191 1.5672 11.6316
Kuramochi GDSC2 3.2222 5.1274 2.3348 6.5457
DOV13 GDSC2 3.6473 5.3319 2.5736 3.8719
TYK-nu GDSC2 3.6523 7.973 1.2656 11.9857
OVCAR-5 GDSC2 3.6773 7.9982 1.2729 11.8729
OVISE GDSC2 3.6931 5.094 2.7229 2.8398
OVTOKO GDSC2 3.8076 7.5801 1.5828 9.6387
TOV-112D GDSC2 3.899 5.6762 2.5841 3.2364
EFO-21 GDSC2 3.9748 8.8416 1.0855 12.1883
OVCAR-8 GDSC2 4.0179 6.1709 2.4274 3.9311
ES-2 GDSC2 4.3165 6.0494 2.6708 1.9742
JHOS-4 GDSC2 4.4054 6.8275 2.3688 3.5161
OV56 GDSC2 4.7852 6.2053 2.8412 0.6413
OVK18 GDSC2 5.0472 6.77 2.7362 0.8267
OVCAR-3 GDSC2 5.0767 6.7393 2.7611 0.7125
JHOS-2 GDSC2 5.159 6.5355 2.8712 0.3263
SK-OV-3 GDSC2 5.1632 7.8894 2.3287 2.5434
EFO-27 GDSC2 5.1741 8.9541 1.8588 5.0442
OAW42 GDSC2 5.3469 11.0403 0.9918 9.5467
Caov-3 GDSC2 5.5277 7.4423 2.6839 0.6694
OV-90 GDSC2 5.5749 12.9728 0.2205 13.0869
OAW28 GDSC2 5.8013 8.9613 2.2022 2.3662
OVCAR-4 GDSC2 5.8592 8.3011 2.4963 1.0828
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Capan-2 GDSC2 3.1511 4.9202 2.3763 6.5032
MIA PaCa-2 GDSC2 3.3822 5.4399 2.3127 6.2164
Panc 10.05 GDSC2 3.5009 5.1193 2.5677 4.2797
PaTu 8902 GDSC2 3.5646 4.8431 2.7528 2.9563
CFPAC-1 GDSC2 3.5963 7.5473 1.4333 11.123
PSN1 GDSC2 3.6221 5.5629 2.4407 4.7651
YAPC GDSC2 3.8023 6.5035 2.1116 6.3724
SUIT-2 GDSC2 3.8047 5.7301 2.4926 4.0022
BxPC-3 GDSC2 3.8226 6.8447 1.9584 7.2758
DAN-G GDSC2 4.0097 9.3013 0.8843 13.2582
HPAC GDSC2 4.1049 9.778 0.7209 13.9276
KP-4 GDSC2 4.1079 6.0292 2.5539 2.9962
Capan-1 GDSC2 4.5221 6.747 2.476 2.7103
PaTu 8988t GDSC2 4.579 13.0806 -0.5534 19.037
AsPC-1 GDSC2 4.7829 7.6708 2.2107 3.7498
KP-3 GDSC2 4.8086 7.7833 2.1747 3.9075
PL4 GDSC2 4.9288 6.9667 2.6005 1.5154
Panc 08.13 GDSC2 5.0369 7.4795 2.4384 2.1614
QGP-1 GDSC2 5.116 10.5144 1.0887 9.4909
HuP-T3 GDSC2 5.1336 8.5625 2.0132 4.2587
HPAF-II GDSC2 5.281 7.8759 2.396 2.0645
Panc 02.03 GDSC2 5.3612 13.612 -0.2385 15.7498
KP-1N GDSC2 5.4181 7.6014 2.5747 1.1415
KP-2 GDSC2 5.4355 6.7124 2.9115 0.1516
SU.86.86 GDSC2 5.5315 6.7903 2.9188 0.1202
HuP-T4 GDSC2 5.7371 7.6787 2.6811 0.5586
MZ-PC-1 GDSC2 6.2795 8.2939 2.6684 0.3584
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC2 3.074 5.089 2.2242 7.7061
MPP 89 GDSC2 3.6588 5.8259 2.3384 5.3138
IST-Mes1 GDSC2 4.2136 6.6477 2.3305 4.1083
MSTO-211H GDSC2 5.2222 7.3899 2.5687 1.3465
NCI-H2052 GDSC2 5.5376 8.0363 2.4554 1.5202
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC2 3.3496 4.9213 2.5452 4.838
22Rv1 GDSC2 3.972 5.9973 2.4795 3.7133
PC-3 GDSC2 4.1551 6.7372 2.2488 4.7188
LNCaP clone FGC GDSC2 4.259 6.3318 2.5078 2.9826
NCI-H660 GDSC2 5.495 6.7294 2.9267 0.1166
DU145 GDSC2 6.091 7.7432 2.7913 0.1875
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 4.8437 8.3244 1.9466 5.1393
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2058 GDSC2 1.7249 11.4038 -2.1165 33.2123
SK-MEL-24 GDSC2 2.0533 3.1234 1.9862 13.0793
GAK GDSC2 2.068 3.3549 1.9444 13.2361
HT-144 GDSC2 2.1539 4.0328 1.8013 13.6713
HMV-II GDSC2 2.1729 3.6956 1.9491 12.7437
SH-4 GDSC2 2.3067 4.0851 1.9413 12.2262
WM1552C GDSC2 2.469 4.7106 1.8321 12.2443
IGR-37 GDSC2 2.6078 3.393 2.5221 7.6221
A101D GDSC2 2.634 3.6414 2.4649 7.8296
G-361 GDSC2 2.666 3.6445 2.4979 7.505
COLO 792 GDSC2 2.7435 3.9716 2.4435 7.5098
IGR-1 GDSC2 2.8782 3.7722 2.669 5.6359
M14 GDSC2 2.896 4.1533 2.5139 6.506
LOX-IMVI GDSC2 2.9213 4.9533 2.1523 8.6588
UACC-62 GDSC2 2.9224 3.7782 2.7118 5.2068
COLO 679 GDSC2 2.973 3.9616 2.6793 5.2113
WM115 GDSC2 2.9953 4.8687 2.2619 7.7257
UACC-257 GDSC2 2.9999 3.8175 2.7727 4.543
WM278 GDSC2 3.0237 4.367 2.5339 5.93
WM793 GDSC2 3.2205 5.2354 2.2794 6.9015
RPMI-7951 GDSC2 3.3844 9.239 0.4153 17.6089
COLO 829 GDSC2 3.5 5.1053 2.5739 4.2429
G-mel GDSC2 3.509 5.0151 2.6258 3.893
Mel JuSo GDSC2 3.5518 5.0178 2.6571 3.5867
A-375 GDSC2 3.5672 5.7556 2.303 5.7725
WT2-iPS GDSC2 3.6157 5.1857 2.6221 3.6465
WM35 GDSC2 3.7299 8.7377 0.9461 13.6578
MZ-MEL-7 GDSC2 3.8773 6.3485 2.2428 5.3759
SK-MEL-5 GDSC2 3.9914 5.883 2.5471 3.2666
VMRC-MELG GDSC2 4.0556 5.929 2.5673 3.0181
A-431 GDSC2 4.347 7.0693 2.2182 4.5078
Mel Ho GDSC2 4.3583 6.6361 2.4282 3.2597
COLO 800 GDSC2 4.4899 10.0283 0.8853 12.042
CHL-1 GDSC2 4.4977 6.5631 2.5446 2.3745
SK-MEL-2 GDSC2 4.5412 9.7934 1.0375 11.0591
SK-MEL-28 GDSC2 4.7303 5.7335 2.9951 0.205
LB2518-MEL GDSC2 4.8167 6.1261 2.8851 0.468
SK-MEL-3 GDSC2 4.8187 6.8213 2.606 1.6184
LB373-MEL-D GDSC2 4.9146 6.2542 2.8774 0.4332
DJM-1 GDSC2 5.1166 7.029 2.665 1.0457
SK-MEL-30 GDSC2 5.1925 6.3026 2.9655 0.1235
IPC-298 GDSC2 5.2159 6.5103 2.9019 0.2327
COLO 783 GDSC2 5.2509 6.6141 2.8782 0.2719
Hs 938.T GDSC2 5.2579 6.5609 2.8996 0.2232
CP66-MEL GDSC2 5.2687 6.5077 2.9222 0.1764
SK-MEL-31 GDSC2 5.3273 6.9756 2.7765 0.5025
MZ-MEL-2 GDSC2 5.3486 7.1111 2.7345 0.619
451Lu GDSC2 5.3759 6.9713 2.7975 0.4183
RVH-421 GDSC2 5.6911 7.0349 2.8917 0.1262
Hs 940.T GDSC2 5.7804 7.8624 2.6304 0.685
MMAc-SF GDSC2 5.8966 7.364 2.852 0.1404
CP50-MEL-B GDSC2 5.9065 7.5677 2.7856 0.2445
A-388 GDSC2 6.1557 8.2306 2.6442 0.4601
EquiPSC Line K2 GDSC2 6.6145 8.8088 2.6114 0.3641
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 3.7997 6.0849 2.3156 5.1096
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh41 GDSC2 2.0148 3.1651 1.935 13.5325
KYM-1 GDSC2 2.6608 3.6619 2.4856 7.5975
SW982 GDSC2 2.7817 5.2004 1.9017 10.6943
G-401 GDSC2 3.0192 4.4504 2.4891 6.2246
G-402 GDSC2 3.5685 12.0829 -0.8548 23.0437
RD GDSC2 3.5895 5.5835 2.4057 5.0682
Rh30 GDSC2 3.6604 6.5789 1.9662 7.6432
HT-1080 GDSC2 4.0751 10.0961 0.5402 14.9957
SK-LMS-1 GDSC2 4.2299 6.2567 2.5245 2.939
MES-SA GDSC2 4.2502 6.9184 2.226 4.6569
SK-UT-1 GDSC2 4.323 7.1101 2.1831 4.7639
GCT GDSC2 4.3345 10.1285 0.7213 13.3375
SW684 GDSC2 4.4731 6.6477 2.4922 2.7007
A-204 GDSC2 5.0271 7.361 2.484 1.9507
VA-ES-BJ GDSC2 5.0311 7.3841 2.4762 1.9834
SW872 GDSC2 5.2749 10.9492 0.9874 9.7191
TE 441.T GDSC2 5.6198 6.8558 2.9273 0.0942
EW-8 GDSC2 5.6387 7.2485 2.7987 0.3048
STS-0421 GDSC2 5.7786 8.4565 2.3986 1.5291
RKN GDSC2 5.81 7.1826 2.8832 0.1157
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 GDSC2 2.2982 3.4276 2.1741 10.9336
NCI-N87 GDSC2 2.3266 4.479 1.793 13.0247
AGS GDSC2 2.8036 4.3702 2.3214 8.0225
MKN1 GDSC2 3.1649 5.7878 1.9558 9.114
MKN28 GDSC2 3.2657 5.7858 2.0428 8.2619
MKN45 GDSC2 3.375 5.0078 2.5228 4.9073
OCUM-1 GDSC2 3.4607 6.6355 1.7793 9.3581
IM95 GDSC2 3.582 6.2279 2.0795 7.1396
GCIY GDSC2 3.6093 5.749 2.3388 5.4378
SNU-1 GDSC2 3.8497 5.8604 2.4611 4.0937
RF-48 GDSC2 3.8844 7.3507 1.7549 8.3817
RERF-GC-1B GDSC2 3.8896 12.0551 -0.5811 20.9806
Hs 746.T GDSC2 3.979 6.134 2.4187 4.0671
KATO III GDSC2 4.0586 6.4651 2.3138 4.5317
SCH GDSC2 4.1112 6.4429 2.3601 4.1408
SNU-5 GDSC2 4.4014 8.4632 1.5859 8.175
23132/87 GDSC2 4.4602 9.9519 0.9011 12.0251
NUGC-4 GDSC2 4.4926 7.2754 2.2148 4.2455
ECC12 GDSC2 4.6893 5.8229 2.9464 0.3533
HGC-27 GDSC2 4.8564 6.5978 2.7174 1.0719
NUGC-3 GDSC2 5.1431 6.8696 2.7395 0.7408
MKN7 GDSC2 5.4946 7.2339 2.7482 0.4949
SK-GT-2 GDSC2 5.6369 7.7006 2.6318 0.7692
TMK-1 GDSC2 5.9615 7.9246 2.6797 0.4555
SNG-M GDSC2 4.3069 8.1678 1.6627 7.9297
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC2 2.8112 4.3232 2.3509 7.8139
B-CPAP GDSC2 3.3514 5.5883 2.2133 6.9336
8305C GDSC2 3.3578 5.0665 2.4794 5.2312
HTC-C3 GDSC2 3.6918 10.1366 0.2177 17.7496
IHH-4 GDSC2 3.9693 6.4846 2.2422 5.1667
WRO GDSC2 4.3476 8.5773 1.4922 8.8575
TT2609-C02 GDSC2 4.4343 7.8344 1.9119 6.1524
BHT-101 GDSC2 4.8113 15.178 -1.4152 21.929
FTC-133 GDSC2 5.1075 7.9315 2.2801 2.8689
CAL-62 GDSC2 5.3219 6.7819 2.8451 0.3209
ASH-3 GDSC2 5.3371 6.7002 2.88 0.2372
8505C GDSC2 5.6464 13.3778 0.0745 13.6465
ML-1 [Human leukemia] GDSC2 5.9337 7.6589 2.7637 0.2781
KMH-2 GDSC2 5.9916 7.7087 2.7675 0.2534
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SAS GDSC2 2.7796 5.3963 1.8041 11.3081
NCI-H3118 GDSC2 2.877 4.3171 2.418 7.1633
HSC-2 GDSC2 2.9175 3.739 2.724 5.1532
Detroit 562 GDSC2 3.158 5.0934 2.2962 6.9873
BB49-HNC GDSC2 3.1832 5.5069 2.1118 8.074
SKN-3 GDSC2 3.2943 6.493 1.7134 10.2493
SCC-9 GDSC2 3.3085 5.9479 1.9978 8.42
HO-1-N-1 GDSC2 3.3221 4.7713 2.5974 4.5871
HSC-3 GDSC2 3.3618 4.6635 2.6841 3.9241
DOK GDSC2 3.4529 6.8944 1.6437 10.2262
BICR 10 GDSC2 3.5656 6.9492 1.7072 9.5165
FaDu GDSC2 3.5944 5.0675 2.6645 3.4344
SAT [Human HNSCC] GDSC2 3.698 6.3008 2.1331 6.5003
JHU-022 GDSC2 3.7245 7.3317 1.6419 9.4932
CAL-27 GDSC2 3.7376 6.2226 2.2018 5.9705
BICR 22 GDSC2 3.8236 5.7881 2.4778 4.0505
SCC-4 GDSC2 3.9201 6.8274 2.0392 6.5345
UPCI-SCC-090 GDSC2 3.9699 13.5894 -1.2823 23.5939
KON GDSC2 4.2716 7.4795 1.9715 6.1436
CAL-33 GDSC2 4.6718 6.5461 2.6473 1.5995
PCI-04B GDSC2 4.9648 7.1578 2.5382 1.7659
HSC-4 GDSC2 5.0709 6.6854 2.7794 0.6526
LB771-HNC GDSC2 5.0837 8.1962 2.1493 3.5977
OSC-19 GDSC2 5.1283 7.517 2.4698 1.896
SCC-25 GDSC2 5.134 7.2754 2.5733 1.416
PCI-15A GDSC2 5.2222 7.0468 2.7052 0.8051
BICR 31 GDSC2 5.3476 7.2904 2.6654 0.8551
JHU-011 GDSC2 5.4606 11.4153 0.8888 9.8734
SCC-15 GDSC2 5.5499 10.3503 1.4453 6.6701
BICR 78 GDSC2 5.5859 7.5477 2.6684 0.6829
BB30-HNC GDSC2 5.7472 7.4339 2.7737 0.3202
KOSC-2 GDSC2 5.7605 8.4943 2.3748 1.6449
Ca9-22 GDSC2 5.761 7.7951 2.6476 0.6436
OSC-20 GDSC2 5.7891 7.9396 2.605 0.7594
PE/CA-PJ15 GDSC2 6.0577 7.7311 2.7836 0.2076
PCI-06A GDSC2 6.0763 7.9462 2.7155 0.3292
BHY GDSC2 6.3639 8.108 2.7632 0.1707
JHU-029 GDSC2 6.4653 9.0701 2.4591 0.8107
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC2 2.7072 4.4779 2.1762 9.2645
BFTC-905 GDSC2 2.8772 4.2155 2.4662 6.8662
RT-112 GDSC2 3.1598 4.5512 2.5675 5.2699
SW1710 GDSC2 3.5884 6.6279 1.8854 8.3409
HT-1197 GDSC2 3.6797 12.7766 -1.1107 23.7432
639V GDSC2 4.6152 5.8177 2.9174 0.494
5637 GDSC2 4.7334 7.0762 2.4497 2.5245
TCCSUP GDSC2 5.1222 9.2626 1.6843 6.1176
647V GDSC2 5.197 11.4105 0.7135 11.3658
SW780 GDSC2 5.2421 8.9106 1.9193 4.5951
RT-4 GDSC2 5.3874 7.135 2.7415 0.5737
CAL-29 GDSC2 5.4487 7.1634 2.7559 0.497
J82 GDSC2 5.5595 7.5225 2.6669 0.7041
T24 GDSC2 5.9266 7.8242 2.7024 0.4146
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC2 1.3962 3.6949 1.1078 20.8662
DoTc2 4510 GDSC2 2.0933 3.4972 1.9294 13.2044
CAL-39 GDSC2 2.613 4.7334 1.9638 10.9086
DSH1 GDSC2 2.8853 4.5093 2.3342 7.6511
NEC8 GDSC2 3.1754 4.6074 2.5533 5.3098
TC-YIK GDSC2 3.5447 6.0324 2.1476 6.8109
SKN GDSC2 3.5476 5.5751 2.3774 5.3551
MS751 GDSC2 3.5688 5.5114 2.4255 4.997
LB831-BLC GDSC2 3.6906 6.3881 2.0842 6.8253
C-4-I GDSC2 3.973 6.2579 2.3547 4.4696
HeLa GDSC2 3.9908 7.0897 1.9623 6.8407
Ca Ski GDSC2 4.159 7.1665 2.0447 5.948
BPH-1 GDSC2 4.2267 10.1933 0.6081 14.232
PEO1 GDSC2 4.231 6.9387 2.2035 4.8316
JEG-3 GDSC2 4.2473 6.8 2.2805 4.3381
HEY GDSC2 4.3372 6.4594 2.4968 2.9055
SKG-IIIa GDSC2 4.4445 10.5296 0.6055 13.6956
OVMIU GDSC2 4.5902 8.9514 1.4812 8.373
PWR-1E GDSC2 4.5915 6.6269 2.5691 2.1038
HEC-1 GDSC2 4.6326 7.0059 2.4236 2.8199
ME-180 GDSC2 4.8548 7.6909 2.244 3.446
SiSo GDSC2 5.0911 7.9441 2.2655 2.9685
SW756 GDSC2 5.0935 10.4473 1.1056 9.4437
HT-3 GDSC2 5.244 7.5114 2.5295 1.4946
OVCA420 GDSC2 5.4477 7.0176 2.8087 0.3569
JAR GDSC2 5.4534 6.8647 2.8652 0.2292
C-33 A GDSC2 5.6148 7.671 2.6337 0.7772
SW954 GDSC2 5.9009 7.7281 2.727 0.3673
ACC-OV7 GDSC2 5.9548 8.1888 2.5797 0.7384
OMC-1 [Human cervical carcinoma] GDSC2 6.0703 7.7485 2.7821 0.207
UWB1.289 GDSC2 6.0809 8.3518 2.5703 0.6948
SW962 GDSC2 6.0928 7.8218 2.765 0.23
OVCA433 GDSC2 6.4983 8.2432 2.7642 0.1447
OV17R GDSC2 6.5242 8.6776 2.6241 0.3677
JHOS-3 GDSC2 6.5932 8.3938 2.7464 0.1505
SiHa GDSC2 8.2519 25.5762 -4.0127 22.7717
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug

References

1 Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochem J. 2014 Jan 1;457(1):215-25.