Details of the Drug

General Information of Drug (ID: DMPK32V)

Drug Name
BMS-754807
Synonyms
BMS-754807; 1001350-96-4; BMS 754807; BMS754807; UNII-W9E3353E8J; CHEMBL575448; CHEBI:88339; W9E3353E8J; 1-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoropyridin-3-yl)-2-methyl-L-prolinamide; W-204348; J-501009; 2-Pyrrolidinecarboxamide, 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-, (2S)-;2-Pyrrolidinecarboxamide, 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridin
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 461.5
Logarithm of the Partition Coefficient (xlogp) 2.9
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C23H24FN9O
IUPAC Name
(2S)-1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide
Canonical SMILES
C[C@]1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F
InChI
InChI=1S/C23H24FN9O/c1-23(21(34)26-15-7-8-18(24)25-13-15)9-3-10-32(23)22-28-20(17-4-2-11-33(17)31-22)27-19-12-16(29-30-19)14-5-6-14/h2,4,7-8,11-14H,3,5-6,9-10H2,1H3,(H,26,34)(H2,27,28,29,30,31)/t23-/m0/s1
InChIKey
LQVXSNNAFNGRAH-QHCPKHFHSA-N
Cross-matching ID
PubChem CID
24785538
ChEBI ID
CHEBI:88339
CAS Number
1001350-96-4
UNII
W9E3353E8J
DrugBank ID
DB15399
TTD ID
D02QWY
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
RAC-alpha serine/threonine-protein kinase (AKT1) TTWTSCV AKT1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cyclin-dependent kinase inhibitor 2A (CDKN2A) OTN0ZWAE CDN2A_HUMAN Drug Response [2]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Drug Response [2]
Insulin-like growth factor 1 receptor (IGF1R) OTXJIF13 IGF1R_HUMAN Post-Translational Modifications [2]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [2]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Drug Response [2]
Ribosomal protein S6 kinase beta-1 (RPS6KB1) OTAELNGX KS6B1_HUMAN Post-Translational Modifications [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
RAC-alpha serine/threonine-protein kinase (AKT1) DTT AKT1 2.63E-29 0.65 1.45
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 2.9807 8.2065 0.5898 17.9019
ES1 GDSC1; GDSC2 -5.1828 3.0925 -5.8979 69.5255
EW-1 GDSC1; GDSC2 -4.7336 0.5232 -4.8932 72.7253
EW-12 GDSC2 -4.6316 9.5746 -7.6075 60.7874
EW-16 GDSC1; GDSC2 -4.5287 6.3537 -6.2299 63.08
NOS-1 [Human HNSCC] GDSC1; GDSC2 -4.1526 7.4818 -6.2552 60.8054
EW-18 GDSC1; GDSC2 -3.7458 3.1902 -4.3557 63.4858
SK-ES-1 GDSC1; GDSC2; CTRP2 -3.6864 2.8593 -3.9884 56.9215
EW-7 GDSC1; GDSC2 -3.1083 3.4433 -3.7291 59.8229
EW-11 GDSC1; GDSC2 -3.098 5.9247 -4.5346 57.7569
SK-N-MC CTRP2 -3.0837 4.4037 -3.6597 53.3211
ES4 GDSC1; GDSC2 -3.0136 2.1481 -3.3107 60.5539
ES8 GDSC1; GDSC2 -2.3813 1.498 -2.5157 56.3975
MHH-ES-1 GDSC1; GDSC2; CTRP2 -1.7857 6.1605 -2.7417 46.5104
TC71 CTRP2 -1.5182 6.9138 -2.703 45.2877
ES5 GDSC1; GDSC2 -1.4445 8.9402 -4.0338 48.9507
SaOS-2 GDSC1; GDSC2; CTRP2 -1.1249 5.1625 -1.721 42.3409
SK-PN-DW GDSC1; GDSC2 -0.7048 5.0499 -1.6413 42.9325
H-EMC-SS GDSC1; GDSC2 -0.6896 6.3446 -2.1362 43.6758
A-673 GDSC1; GDSC2; CTRP2 -0.6498 4.8778 -1.1252 39.1857
EW-13 GDSC1; GDSC2 -0.2045 4.3902 -0.8633 38.0066
EW-22 GDSC2 -0.2023 6.1309 -1.5369 39.8891
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 0.0357 4.1685 -0.2099 34.1519
HuO9 GDSC1; GDSC2 0.2408 4.6624 -0.4826 34.2214
ES6 GDSC1; GDSC2 0.3371 13.8007 -4.5739 42.3271
NY GDSC1; GDSC2 0.8635 3.9 0.4615 26.7714
ES7 GDSC1; GDSC2 0.9192 4.2289 0.4061 26.8028
CHSA8926 GDSC1; GDSC2 1.5353 3.5941 1.2915 19.2284
HuO-3N1 GDSC1; GDSC2 1.5363 9.2213 -1.222 31.1856
CADO-ES1 GDSC2 1.5945 5.5554 0.5681 23.0221
CAL-78 GDSC1; GDSC2; CTRP2 1.6622 4.7073 1.4396 23.302
MG-63 GDSC1; GDSC2; CTRP2 1.7406 9.1943 -0.1679 28.5446
SJSA-1 GDSC1; GDSC2; CTRP2 1.9912 11.7216 -1.0867 30.4212
Hs 888.T CTRP2 2.1152 4.7877 1.9139 20.2125
SW1353 CTRP2 2.1839 4.7703 1.993 19.7182
TC-71 GDSC1; GDSC2 2.2295 5.0258 1.4482 15.4623
CHSA0108 GDSC1; GDSC2 2.7575 11.4999 -1.2464 27.0135
U-CH2 GDSC2 2.8378 5.2582 1.9257 10.3546
CAL-72 GDSC1; GDSC2 3.1129 14.6127 -2.4986 29.8928
EW-24 GDSC1; GDSC2 3.2356 4.9647 2.4275 5.9183
EW-3 GDSC1; GDSC2 3.3118 11.8626 -0.9569 24.2057
CHSA0011 GDSC1; GDSC2 3.3207 5.1873 2.3882 5.9151
Hs 822.T CTRP2 4.4656 8.4701 2.8281 10.4923
U2OS GDSC1; GDSC2; CTRP2; CTRP1 4.5228 16.2161 -0.9725 24.1261
HOS GDSC1; GDSC2; CTRP2 5.1995 10.1379 2.6257 9.8536
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 1.725 3.254 1.7133 22.1535
MEC1 CTRP2 1.954 5.1061 1.6547 21.6352
JM1 GDSC1; GDSC2; CTRP2 0.4774 4.6597 0.1598 31.4756
NCI-H929 GDSC2; CTRP2 -6.6823 -2.73 -6.6876 76.3521
KMS-26 CTRP2 -6.531 -5.4445 -6.531 77.1138
KMS-34 CTRP2 -6.4118 -4.4804 -6.4118 76.2207
A4/Fukuda GDSC1; GDSC2; CTRP2 -5.8892 0.3275 -6.0055 69.2275
MM1.S GDSC2; CTRP2 -4.8378 -1.6116 -4.8413 65.5549
KHM-1B CTRP2 -4.7865 -1.7135 -4.789 65.2763
KMS-11 GDSC2; CTRP2; CTRP1 -4.4351 6.1819 -5.6293 58.5198
ML-2 GDSC1; GDSC2 -3.659 1.7161 -3.9259 65.0752
PL21 CTRP2; CTRP1 -3.0055 4.0012 -3.4774 53.0356
MOLP-8 GDSC1; GDSC2; CTRP2 -2.9447 5.7316 -3.8712 52.3843
OCI-Ly7 GDSC2 -2.7361 2.5735 -3.1011 58.3019
NB4 GDSC1; GDSC2; CTRP2 -2.6482 1.7208 -2.7296 51.1933
RS4;11 GDSC1; GDSC2; CTRP2 -2.5779 4.1532 -3.0487 50.6566
SKM-1 GDSC2; CTRP2; CTRP1 -2.3726 2.0967 -2.4753 49.4881
KMS-18 CTRP2 -2.3012 1.0533 -2.3258 48.9526
KMS-12-BM GDSC1; GDSC2; CTRP2 -2.283 6.5687 -3.4149 49.1342
KMS-20 CTRP2 -2.2579 2.526 -2.4049 48.7321
OCI-AML-5 GDSC1; GDSC2; CTRP2 -2.1622 3.4231 -2.4445 48.2093
ALL-SIL GDSC1; GDSC2; CTRP2 -1.5048 2.8194 -1.6412 43.9173
KMS-28BM CTRP2 -1.3951 6.1878 -2.3257 44.366
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -1.2431 4.2453 -1.6168 42.6808
SUP-B8 GDSC2 -1.2091 0.6164 -1.2162 45.4928
OPM-2 GDSC1; GDSC2 -0.9108 2.1079 -1.0315 42.8808
KMS-21-BM CTRP2 -0.8973 3.8628 -1.1598 40.2674
PL-21 GDSC1; GDSC2 -0.6476 11.0882 -4.2178 45.584
CCRF-CEM GDSC1; GDSC2 -0.5851 0.2704 -0.5851 39.2044
HL-60 GDSC1; GDSC2; CTRP2 -0.5 6.3169 -1.3961 39.182
ALL-PO GDSC1; GDSC2 -0.4495 0.8685 -0.4517 37.8547
Kasumi-1 GDSC2; CTRP2 -0.4329 3.6734 -0.6224 37.0621
NOMO-1 GDSC1; GDSC2; CTRP1 -0.4289 5.2697 -0.989 47.4841
NALM-6 GDSC1; GDSC2; CTRP2 -0.4267 2.3749 -0.4611 36.5597
KE-37 GDSC1; GDSC2; CTRP2 -0.3779 0.1575 -0.3779 36.124
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 -0.3492 11.4492 -3.294 41.608
DEL GDSC1; GDSC2; CTRP2 -0.3391 0.6242 -0.3391 35.8654
697 GDSC1; GDSC2; CTRP2 -0.3389 0.2536 -0.3389 35.8645
SIG-M5 GDSC1; GDSC2; CTRP2 -0.2653 1.0071 -0.2654 35.3743
Mino CTRP2 -0.245 0.3933 -0.245 35.2387
OCI-Ly19 GDSC1; GDSC2; CTRP2 -0.2433 3.6825 -0.4195 35.7774
P32/ISH GDSC1; GDSC2 -0.2282 0.391 -0.2282 35.6236
L-363 GDSC1; GDSC2; CTRP2 -0.2065 5.3646 -0.7766 36.6316
P30/OHK GDSC1; GDSC2 -0.1941 1.9389 -0.2447 35.5256
WSU-NHL GDSC1 -0.1496 4.7512 -1.7159 28.8185
BC-1 GDSC1; GDSC2 -0.1464 3.7236 -0.58 36.6749
Karpas-45 GDSC1; GDSC2 -0.1271 2.4495 -0.2449 35.1692
SU-DHL-16 GDSC1; GDSC2 -0.1204 1.9442 -0.1673 34.7706
MOLT-4 GDSC1; GDSC2 -0.1201 0.5583 -0.1201 34.5386
ATN-1 GDSC1; GDSC2 -0.1036 3.1389 -0.3681 35.5842
BE-13 GDSC1; GDSC2 -0.0865 0.9135 -0.087 34.2038
MV4-11 GDSC1; GDSC2; CTRP2 -0.0453 1.2608 -0.0455 33.9089
OCI-AML-2 GDSC1; GDSC2; CTRP2 -0.0367 4.6801 -0.4057 34.9932
P12-Ichikawa GDSC1; CTRP2 -0.0092 0.4441 -0.0092 33.6677
KO52 CTRP2 -0.0025 1.4394 -0.0031 33.625
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 0.0595 6.3869 -0.8099 35.8042
MOLM-13 GDSC1; GDSC2; CTRP2 0.0945 1.2896 0.0943 32.9776
Reh GDSC1; GDSC2; CTRP2 0.1002 4.8073 -0.2885 34.163
QIMR-WIL GDSC1; GDSC2 0.1104 3.0389 -0.1099 33.2927
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 0.1191 6.5529 -0.8031 35.5748
ST486 GDSC1; CTRP2 0.1713 1.8816 0.1684 32.4749
Karpas-231 GDSC1; GDSC2 0.2257 1.3695 0.223 31.0824
AML-193 CTRP2 0.3591 6.9188 -0.6801 34.3588
BONNA-12 GDSC2 0.3802 3.5126 0.0575 31.1281
HAL-01 GDSC1; GDSC2 0.4061 2.5942 0.3048 29.771
BV-173 GDSC1; GDSC2; CTRP2 0.4932 2.3732 0.4848 30.3486
SEM CTRP2 0.5015 1.3181 0.5015 30.2655
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 0.5387 5.9898 -0.1565 32.3227
HPB-ALL CTRP2 0.6565 3.8793 0.5161 29.7047
KG-1 GDSC1; GDSC2 0.6689 2.3163 0.6265 26.8368
KOPN-8 GDSC1; GDSC2 0.6898 4.1983 0.17 29.0697
MOLT-3 CTRP2 0.694 1.125 0.694 28.9833
NCO2 CTRP2 0.6951 3.8161 0.568 29.4035
GA-10 GDSC2; CTRP2 0.7443 1.9199 0.744 28.6488
Peer CTRP2 0.758 3.2196 0.7102 28.7172
MOLT-16 GDSC1; GDSC2; CTRP2 0.7813 1.6675 0.7813 28.4011
SUP-M2 GDSC1; GDSC2; CTRP2 0.7837 1.2877 0.7837 28.3855
KMS-27 CTRP2 0.7864 8.9281 -1.0327 33.8432
BL-41 GDSC1; GDSC2 0.8172 2.1973 0.7943 25.2495
TK [Human B-cell lymphoma] GDSC1; GDSC2 0.8306 12.3258 -3.394 39.0849
NKM-1 GDSC1; GDSC2 0.9375 3.2115 0.7491 24.9076
Ki-JK CTRP2 0.9933 2.1459 0.9929 26.9902
SR GDSC1; GDSC2; CTRP2 1.0254 2.2108 1.0247 26.7774
MOLM-16 GDSC2; CTRP2; CTRP1 1.0324 3.0171 1.0117 26.8684
H9 GDSC1; GDSC2 1.1002 3.5599 0.8284 23.7288
SK-MM-2 GDSC1; GDSC2; CTRP2 1.1048 6.4216 0.3034 28.9707
CTB-1 GDSC1; GDSC2 1.1593 4.037 0.734 23.9727
EM-2 GDSC1; GDSC2; CTRP2 1.1842 4.3015 1.0087 26.3161
KMOE-2 GDSC1; GDSC2 1.2013 7.7831 -0.8529 31.2045
Kasumi-2 CTRP2 1.2348 4.9982 0.8994 26.5353
DoHH2 GDSC1; GDSC2 1.3161 2.2782 1.3072 20.1718
Karpas-299 GDSC1; GDSC2; CTRP2 1.3227 2.2957 1.3225 24.7952
MOLM-6 CTRP2 1.3326 3.8142 1.2511 25.0046
HC-1 GDSC1; GDSC2 1.3356 3.9508 0.9549 21.9792
CESS GDSC1; GDSC2 1.3435 5.0438 0.5334 24.254
CRO-AP2 GDSC2 1.3469 2.9549 1.2545 20.2974
EoL-1 GDSC1; GDSC2; CTRP2 1.3575 3.2218 1.3357 24.6357
KE-97 CTRP2 1.3668 4.1702 1.2314 24.9624
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 1.3941 2.3775 1.3939 24.3926
RPMI-8866 GDSC1; GDSC2 1.3952 2.5186 1.3721 19.4507
MEG-01 GDSC1; GDSC2 1.4076 5.3096 0.4857 24.2374
Farage GDSC1; GDSC2 1.4191 3.6046 1.1617 20.4654
SUP-T1 GDSC1; GDSC2; CTRP2 1.4257 8.5578 -0.2115 29.605
SUP-B15 GDSC1; GDSC2; CTRP2 1.4346 4.1006 1.3166 24.4509
P31/FUJ GDSC1; GDSC2; CTRP2 1.4411 2.7363 1.4385 24.014
CTV-1 GDSC1; GDSC2 1.5156 3.6863 1.2404 19.5994
IM-9 GDSC1; GDSC2 1.5182 3.002 1.4307 18.5524
SU-DHL-1 GDSC1; GDSC2; CTRP2 1.5327 2.1116 1.5327 23.3953
BALL-1 GDSC1; GDSC2 1.5422 5.2876 0.6337 22.8771
BL-70 CTRP2; CTRP1 1.5562 3.9127 1.4774 23.5797
MC116 GDSC1; GDSC2; CTRP2 1.5598 1.886 1.5598 23.2149
Loucy GDSC1; GDSC2 1.5685 5.8408 0.413 23.9573
SCC-3 GDSC1; GDSC2 1.5795 2.229 1.5779 17.4925
SU-DHL-10 GDSC2; CTRP2 1.6288 3.9103 1.5542 23.0081
MHH-CALL-4 GDSC2; CTRP2 1.631 5.4164 1.2114 24.2094
RPMI-8402 GDSC1; GDSC2; CTRP2 1.6334 4.9836 1.3383 23.75
VAL GDSC1; GDSC2 1.6821 4.4431 1.1376 19.4635
LC4-1 GDSC1; GDSC2 1.6823 4.8154 0.9827 20.3472
MY-M12 GDSC1; GDSC2 1.6833 4.13 1.2625 18.7458
JURL-MK1 GDSC1; GDSC2; CTRP2 1.6987 4.0117 1.6145 22.5755
JSC-1 GDSC1; GDSC2 1.7871 4.641 1.1657 18.8683
JVM-3 GDSC1; GDSC2; CTRP2 1.8099 4.0544 1.7273 21.8293
KM-H2 GDSC1; GDSC2; CTRP2 1.8676 5.087 1.5657 22.2185
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 1.8832 5.4016 1.4938 22.5045
SUP-HD1 GDSC1; GDSC2; CTRP2 1.9028 5.811 1.3796 22.7852
Mono-Mac-1 CTRP2 1.9248 6.5499 1.1364 23.6045
BC-3 GDSC1; GDSC2 1.931 5.3643 0.9943 19.2859
Hs 611.T CTRP2 1.9559 7.5953 0.749 24.9009
A3/Kawakami GDSC1; GDSC2; CTRP2 1.9595 4.0781 1.8839 20.8088
CMK CTRP2 1.9662 4.0986 1.888 20.773
Daudi GDSC1; GDSC2; CTRP2 2.0052 4.5306 1.8524 20.7731
MOLT-13 GDSC2; CTRP2 2.0228 6.1294 1.3978 22.3651
PF-382 GDSC1; GDSC2; CTRP2 2.0277 5.878 1.4919 22.0058
Sc-1 GDSC1 2.0491 4.698 0.2216 6.7169
Ramos.2G6.4C10 GDSC1; GDSC2 2.0614 4.7859 1.3863 16.4796
SUP-T11 CTRP2 2.0713 5.3401 1.7144 21.0643
RPMI-6666 GDSC1; GDSC2; CTRP2 2.1856 5.9249 1.6464 20.9744
L-540 GDSC1; GDSC2; CTRP2 2.2045 4.7571 2.0186 19.5634
LAMA-84 GDSC1; GDSC2; CTRP2 2.2075 5.4798 1.8194 20.2738
JeKo-1 GDSC2; CTRP2 2.2218 6.6722 1.4055 21.7631
HuT 78 CTRP2 2.2305 8.1943 0.7755 24.0339
RCH-ACV GDSC2; CTRP2 2.2384 5.8932 1.7146 20.5685
Ri-1 CTRP2 2.3155 6.5779 1.542 20.989
JJN-3 GDSC1; GDSC2; CTRP2 2.3556 7.9668 1.0037 22.8697
MOTN-1 CTRP2 2.3656 6.2967 1.7039 20.2413
Namalwa GDSC1; GDSC2; CTRP2 2.3748 4.5723 2.245 18.2316
Ku812 GDSC1; GDSC2; CTRP2 2.3862 5.7053 1.9394 19.3043
NK-92MI GDSC1; GDSC2 2.3969 7.1922 0.5705 19.9639
Granta-519 GDSC1; GDSC2; CTRP2 2.4456 5.4361 2.0923 18.5657
JVM-2 GDSC1; GDSC2; CTRP2 2.5211 5.0921 2.2775 17.664
KY821 GDSC1; GDSC2 2.6018 3.6878 2.4127 8.265
Jurkat GDSC2; CTRP2 2.6482 6.4982 1.9267 18.6039
RC-K8 GDSC1 2.6683 4.5231 0.6862 2.0227
Mono-Mac-6 GDSC1; GDSC2; CTRP2 2.7018 7.9506 1.3648 20.5968
WIL2 NS GDSC1; GDSC2 2.7271 5.7544 1.5802 12.8719
F-36P CTRP2 2.7615 6.7894 1.928 18.2867
ARH-77 GDSC1; GDSC2 2.7775 8.2809 0.3753 19.7226
CML-T1 GDSC2; CTRP2 2.7911 6.4867 2.0826 17.6126
EJM GDSC1; GDSC2; CTRP2; CTRP1 2.8061 11.4259 -0.1533 25.6694
SET-2 CTRP2 2.8281 9.0542 0.9872 21.6708
M-07e CTRP2 2.85 11.0317 0.0706 24.7851
GR-ST GDSC1; GDSC2 2.8743 7.4652 0.8664 16.6786
SU-DHL-6 GDSC1; GDSC2; CTRP2 3.0414 5.3952 2.7536 14.3672
NU-DHL-1 CTRP2 3.0567 6.9501 2.1678 16.5632
Pfeiffer CTRP2 3.079 6.1235 2.5319 15.0941
HD-MY-Z CTRP2 3.2354 6.6378 2.4866 14.8428
Karpas-1106P GDSC2 3.2516 6.4627 1.6926 10.5057
DG-75 GDSC1; GDSC2 3.2805 5.339 2.2787 6.7255
Karpas-422 GDSC1; GDSC2; CTRP2 3.4462 6.644 2.7025 13.4369
EB1 CTRP2 3.4592 6.7861 2.6539 13.5944
EHEB GDSC1; CTRP2 3.4861 7.622 2.3038 14.9185
HDLM-2 GDSC1; GDSC2; CTRP2 3.5448 6.9808 2.6549 13.3691
MHH-PREB-1 GDSC1; GDSC2 3.626 5.6849 2.3833 5.1151
SU-DHL-5 GDSC1; GDSC2; CTRP1 3.6524 8.4745 2.0731 19.7836
CA46 GDSC1; GDSC2; CTRP2 3.7023 7.4479 2.5991 13.1968
TF-1 CTRP2 3.7153 7.7507 2.4701 13.6853
OCI-M1 GDSC1; GDSC2; CTRP2 3.73 6.6928 2.9719 11.6322
Jiyoye GDSC1; GDSC2 3.7305 8.6388 0.9958 13.3666
Hs 445 GDSC1; GDSC2 3.7791 7.4102 1.6452 9.3282
L-1236 GDSC1; GDSC2 3.8142 5.818 2.4566 4.2022
DND-41 GDSC1; GDSC2; CTRP2 3.8176 7.3631 2.7523 12.2949
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 3.8261 6.2927 3.2524 10.3555
MHH-CALL-3 CTRP2 3.8402 8.0296 2.459 13.4301
MLMA GDSC1; GDSC2 3.8639 6.4516 2.1826 5.7806
SU-DHL-8 GDSC1; GDSC2; CTRP2 3.8925 6.4474 3.2466 10.1205
KYO-1 CTRP2 3.9017 6.6506 3.1647 10.4243
EB2 GDSC1; GDSC2 3.9441 7.7959 1.5799 9.305
OCI-Ly10 CTRP2; CTRP1 3.9786 9.7295 1.7718 15.9538
KCL-22 GDSC1; GDSC2; CTRP2 4.0833 8.0327 2.6894 11.9201
YT GDSC1; GDSC2 4.097 7.4641 1.8558 7.2428
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 4.2022 8.6608 2.5021 12.4988
DB GDSC1; GDSC2 4.2297 7.7478 1.8123 7.201
K-562 GDSC1; GDSC2; CTRP2 4.3921 5.956 3.9738 5.9408
OCI-Ly3 CTRP2 4.4209 8.1499 2.9457 10.1013
VL51 GDSC1; GDSC2 4.5476 8.5452 1.6477 7.483
RL GDSC1; GDSC2; CTRP2 4.7359 5.3752 4.5828 2.6316
U-698-M GDSC1; GDSC2 4.7654 10.413 0.8955 11.3361
ME1 GDSC1; GDSC2 4.9452 6.1913 2.9128 0.3162
U-937 CTRP2; CTRP1 4.9781 8.5834 3.2288 7.8409
MN-60 GDSC1; GDSC2 5.0055 8.3245 2.0454 4.2938
HEL 92.1.7 CTRP2 5.0334 10.318 2.3984 11.1121
HEL GDSC1; GDSC2; CTRP2 5.0465 12.2978 1.4195 15.0014
HT GDSC1; GDSC2; CTRP2 5.083 9.8881 2.6546 9.9559
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 5.11 6.6276 4.3167 3.0195
ROS-50 GDSC1; GDSC2 5.164 10.0633 1.3351 8.0116
TUR GDSC1; GDSC2 5.1795 7.2604 2.6011 1.2506
MOLP-2 CTRP2 5.22 17.4007 -0.9881 22.7071
L-428 GDSC1; GDSC2; CTRP2 5.2987 9.7271 2.9114 8.4798
U266B1 GDSC1; GDSC2; CTRP2 5.6483 15.0144 0.5533 17.0245
HH [Human lymphoma] GDSC1; GDSC2 5.8468 11.5124 1.0908 8.0481
P3HR-1 CTRP2 6.429 9.4221 3.8737 2.8028
ME1 CTRP2 6.5658 12.755 2.3717 8.5629
REC-1 CTRP2 6.9428 14.0711 1.9986 9.4523
KMM-1 CTRP2 6.9776 18.3117 -0.0551 16.717
Toledo CTRP2 7.0651 11.8085 3.1614 4.7535
Raji GDSC1; GDSC2; CTRP2 7.1097 8.3778 4.6364 0.1058
Karpas-620 GDSC1; GDSC2; CTRP2 7.1115 8.3381 4.6506 0.0906
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 1.6019 7.403 0.4568 26.9404
TE15 CTRP2 1.8824 7.1438 0.8578 24.7282
TE-8 GDSC1; GDSC2 -3.8188 15.8997 -9.591 55.8354
TE-11 GDSC1; GDSC2; CTRP2 -2.9699 2.1614 -3.1162 53.1281
T.T GDSC1; GDSC2 -0.27 9.0438 -2.8939 42.6742
KYSE-270 GDSC1; GDSC2 -0.0057 3.036 -0.2357 34.4776
TE-1 GDSC1; GDSC2; CTRP2 1.9055 10.2876 -0.4995 29.0581
OE21 GDSC1; GDSC2 2.2178 12.3623 -2.1485 31.6407
KYSE-140 GDSC1; GDSC2; CTRP2 2.3361 7.5108 1.1807 22.2749
OE33 GDSC1; GDSC2; CTRP2 2.556 7.1446 1.5647 20.2339
TE-15 GDSC1; GDSC2 2.5903 7.5286 0.5816 19.2327
TE-9 GDSC1; GDSC2; CTRP2 2.8802 8.5069 1.2923 20.402
KYSE-70 GDSC1; GDSC2; CTRP2 2.9629 6.9906 2.0533 17.2585
KYSE-520 GDSC1; GDSC2; CTRP2 3.3859 7.955 2.0502 16.1784
TE-6 GDSC1; GDSC2; CTRP2 3.4273 6.9379 1.601 8.5856
TE-10 GDSC1; GDSC2; CTRP2 3.7236 10.1832 1.3055 18.2807
EC-GI-10 GDSC1; GDSC2; CTRP2 3.725 7.3068 2.687 12.7864
KYSE-410 GDSC1; GDSC2; CTRP2 3.8067 9.0689 1.9262 15.6586
TE-4 GDSC2; CTRP2 3.8368 7.5415 2.6875 12.5107
KYSE-180 GDSC1; GDSC2; CTRP2 3.9576 7.8858 2.6406 12.413
KYSE-150 GDSC1; GDSC2; CTRP2 4.85 9.3238 2.7406 10.0561
KYSE-30 CTRP2 5.0226 12.6787 1.209 15.8511
TE-14 CTRP2 5.1439 7.4376 3.9296 4.4972
KYSE-450 GDSC1; GDSC2; CTRP2 5.3573 8.1131 3.7623 4.8144
TE-5 GDSC1; GDSC2 6.063 7.7969 2.7628 0.2418
COLO 680N GDSC1; GDSC2; CTRP2 6.3687 11.766 2.7131 7.4985
KYSE-510 GDSC1; GDSC2; CTRP2 8.1193 18.0889 0.8728 11.8567
OE19 GDSC1; GDSC2; CTRP2 9.7482 23.2024 -0.4771 13.9465
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.8413 15.7551 -1.3439 26.543
MZ-PC-1 GDSC1; GDSC2 -1.3968 15.6411 -7.1066 49.1765
PaTu 8988s CTRP2 -0.4315 17.2677 -6.0689 44.1466
Panc 08.13 GDSC1; GDSC2; CTRP2 -0.1449 5.5938 -0.7779 36.4073
HPAC GDSC1; GDSC2; CTRP2 0.4145 5.0676 -0.0147 32.2426
KP-4 GDSC1; GDSC2; CTRP2 0.6478 2.5678 0.6364 29.3289
Capan-2 GDSC1; CTRP2 0.6515 7.8931 -0.7445 33.5462
TCC-Pan2 CTRP2 0.8957 10.5305 -1.6241 34.8662
PL4 GDSC1; GDSC2 1.1618 4.3295 0.629 24.5298
BxPC-3 GDSC1; GDSC2; CTRP2 1.3988 5.9469 0.7873 26.4177
HuP-T4 GDSC1; GDSC2; CTRP2 1.542 5.8454 0.9769 25.3145
PaTu 8902 GDSC1; GDSC2; CTRP2; CTRP1 1.5423 7.6172 0.3117 27.6681
KP-1N GDSC1; GDSC2 1.6208 8.249 -0.6713 28.809
Panc 03.27 GDSC1; GDSC2; CTRP2 1.917 6.5478 1.1288 23.6548
PK-59 CTRP2 1.9582 6.3335 1.2536 23.0812
KP-3 GDSC1; GDSC2; CTRP2 1.9661 10.6669 -0.6155 29.2194
DAN-G GDSC1; GDSC2; CTRP2 2.0011 6.4443 1.258 22.9403
Capan-1 GDSC1; GDSC2; CTRP2 2.1319 9.3845 0.1415 26.4626
KP-2 GDSC1; GDSC2; CTRP2 2.2636 7.2573 1.212 22.361
HuP-T3 GDSC1; GDSC2; CTRP2 2.587 13.4346 -1.3409 29.5017
SNU-213 CTRP2 2.7828 16.6513 -2.737 32.1129
YAPC GDSC1; GDSC2; CTRP2 2.9055 10.7815 0.2439 24.0753
SW1990 GDSC1; GDSC2; CTRP2 2.9131 5.7159 2.5057 15.6635
Panc 10.05 GDSC1; GDSC2; CTRP2 3.0977 8.7765 1.3827 19.5034
Panc 05.04 CTRP2 3.2133 10.7704 0.5417 22.2933
AsPC-1 GDSC1; GDSC2; CTRP2 3.3699 9.8377 1.1409 19.7438
Panc 02.03 GDSC1; GDSC2; CTRP2 3.9528 6.7553 3.1683 10.2812
SU.86.86 GDSC1; GDSC2; CTRP2 4.1796 8.3361 2.632 11.9355
Panc 04.03 GDSC1; GDSC2; CTRP2 4.3516 11.6174 1.1641 17.4103
MIA PaCa-2 GDSC1; GDSC2; CTRP2 4.5638 14.2605 0.03 20.9506
PK-45H CTRP2 4.6954 6.7771 3.8724 5.6438
SUIT-2 GDSC1; GDSC2; CTRP2 4.8866 16.0104 -0.5706 22.16
PSN1 GDSC1; GDSC2; CTRP2 4.9763 10.4735 2.2729 11.7394
L3.3 CTRP2 4.9767 8.6844 3.1677 8.0182
Hs 766T GDSC1; GDSC2; CTRP2 5.4056 7.4261 4.1395 3.1609
PaTu 8988t GDSC1; GDSC2; CTRP2 5.9294 14.2819 1.1409 14.3935
SNU-410 CTRP2 6.2912 12.3042 2.3939 8.9054
CFPAC-1 GDSC1; GDSC2; CTRP2 6.7043 10.8975 3.3586 4.4476
HPAF-II GDSC1; CTRP2 7.0325 21.2416 -1.4629 20.7447
QGP-1 GDSC2; CTRP2 7.2784 16.3432 1.1312 12.1877
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 4.8908 24.7289 -4.9262 31.5963
WM35 GDSC1; GDSC2 -2.1742 6.4643 -3.753 52.8841
Hs 852.T CTRP2; CTRP1 -0.6487 9.7692 -2.8775 42.1302
HMV-II GDSC1; GDSC2 -0.2502 22.1871 -9.2311 46.6182
Hs 688(A).T CTRP2 -0.0997 7.6931 -1.4636 37.8283
VMRC-MELG GDSC1; GDSC2 0.1298 5.5035 -0.9298 36.4263
COLO 792 GDSC1; GDSC2; CTRP2 0.8584 9.5479 -1.2261 34.0824
SH-4 GDSC1; GDSC2 1.169 6.8085 -0.4299 29.656
M14 GDSC1 1.3162 5.5891 -0.7937 16.698
A-431 GDSC1; GDSC2 1.5532 5.8131 0.4101 24.0349
A-388 GDSC1; GDSC2 1.568 6.5803 0.0715 25.7003
A-375 GDSC1; GDSC2; CTRP2; CTRP1 1.7234 8.8937 -0.0458 28.2799
WM1552C GDSC1; GDSC2 1.7609 7.4276 -0.1425 25.9614
Hs 940.T GDSC1; GDSC2; CTRP2 2.065 8.6719 0.3951 25.8112
CP66-MEL GDSC1; GDSC2 2.3039 16.6754 -4.221 35.9115
MZ-MEL-2 GDSC1; GDSC2 2.3225 16.7367 -4.2355 35.8851
Hs 934.T CTRP2 2.4011 3.8082 2.3807 17.6786
Hs 895.T CTRP2 2.4145 6.4666 1.6909 20.151
SK-MEL-24 GDSC1; GDSC2; CTRP2 2.7769 12.4124 -0.6658 27.2134
COLO 783 GDSC1; GDSC2 2.834 14.6204 -2.7388 31.3222
A2058 GDSC1; GDSC2; CTRP2 3.0318 5.8838 2.5728 15.0714
RPMI-7951 GDSC1; GDSC2; CTRP2 3.0386 8.0483 1.661 18.5839
LOX-IMVI GDSC1; GDSC2; CTRP2 3.0386 5.9042 2.5725 15.0529
CJM [Human melanoma] CTRP2 3.0908 5.7911 2.6703 14.5352
HMCB CTRP2 3.1438 5.5209 2.823 13.8094
Hs 294T CTRP2 3.2367 6.5773 2.5135 14.7345
DJM-1 GDSC1; GDSC2 3.3727 6.775 1.6375 10.4935
MMAc-SF GDSC1; GDSC2 3.382 16.4981 -3.2162 30.977
A101D GDSC1; GDSC2; CTRP2 3.4563 6.1317 2.9284 12.5274
CP50-MEL-B GDSC1; GDSC2 3.725 13.0829 -1.2269 24.058
HT-144 GDSC1; GDSC2; CTRP2 3.731 9.5244 1.6338 16.9928
LB2518-MEL GDSC1; GDSC2 3.7323 12.465 -0.9123 22.8095
G-mel GDSC1; GDSC2 3.8942 10.0829 0.4058 16.2017
UACC-257 GDSC1; GDSC2; CTRP2 4.136 9.9302 1.8085 15.3793
MZ-MEL-7 GDSC1; GDSC2 4.2033 8.8672 1.2452 10.6689
WM1799 CTRP2 4.2179 9.4719 2.1091 13.9897
GAK GDSC1; GDSC2 4.2544 7.663 1.8708 6.7904
Hs 944.T CTRP2 4.273 13.4318 0.1917 21.0394
Hs 839.T CTRP2 4.2759 6.7666 3.4816 8.22
MDA-MB-435S CTRP2 4.4053 12.1239 0.9588 18.0597
G-361 GDSC1; GDSC2; CTRP2 4.4054 10.66 1.6877 15.2718
Hs 938.T GDSC1; GDSC2 4.407 9.2939 1.1848 10.5286
IGR-39 CTRP2 4.419 8.693 2.6759 11.2245
IGR-1 GDSC1; GDSC2; CTRP2 4.6285 12.4368 0.9962 17.4497
SK-MEL-2 GDSC1; GDSC2; CTRP2 4.635 5.0369 4.5996 2.8509
COLO 829 GDSC1; GDSC2; CTRP2 4.6493 11.7508 1.3565 16.0487
WT2-iPS GDSC1; GDSC2; CTRP2 4.7266 10.0686 2.2628 12.282
COLO 679 GDSC1; GDSC2 4.7409 14.5543 -1.16 21.1353
WM266-4 CTRP2 4.8943 10.174 2.3535 11.571
WM278 GDSC1; GDSC2 4.9963 12.0814 0.2471 14.2418
WM793 GDSC1; GDSC2; CTRP2 5.0311 10.5024 2.3043 11.5031
WM88 CTRP2 5.2511 11.9811 1.7468 13.3258
MeWo GDSC1; GDSC2; CTRP2 5.2514 10.2208 2.6266 9.7521
Mel Ho GDSC1; GDSC2; CTRP2 5.2834 8.4297 3.5466 5.8493
COLO 800 GDSC1; GDSC2; CTRP2 5.3159 12.2044 1.688 13.4337
451Lu GDSC1; GDSC2 5.4765 9.2455 1.9046 4.2985
IST-MEL1 GDSC1; GDSC2 5.5211 13.8382 -0.2353 15.3771
WM983B CTRP2 5.7141 16.5593 -0.1649 19.2939
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 5.7196 10.3746 2.9296 7.737
CHL-1 GDSC1; GDSC2 5.7618 7.7843 2.652 0.6302
RVH-421 GDSC1; GDSC2; CTRP2 5.7981 8.6449 3.827 3.8325
LB373-MEL-D GDSC1; GDSC2 5.8929 18.9916 -2.4872 23.0539
Mel JuSo GDSC1; GDSC2; CTRP2 6.1375 14.7595 1.065 14.3042
IPC-298 GDSC1; GDSC2; CTRP2 6.2486 14.5254 1.2663 13.3662
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 6.3873 11.9851 2.6308 7.8748
Hs 936.T CTRP2 6.4748 16.0862 0.6656 15.1512
SK-MEL-31 GDSC2; CTRP2 6.521 16.5943 0.4491 15.8201
IGR-37 GDSC1; GDSC2; CTRP2 6.7894 12.1421 2.8234 6.4395
K029AX CTRP2 6.8334 13.8098 2.0484 9.4249
WM115 GDSC1; GDSC2; CTRP2 7.062 15.1477 1.5595 10.944
COLO 741 CTRP2 7.1417 17.8948 0.2722 15.382
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 8.3623 14.3217 2.8048 4.6572
UACC-62 GDSC1; GDSC2; CTRP2 8.5901 17.2514 1.5822 8.7271
SK-MEL-30 GDSC1; GDSC2; CTRP2 9.5669 18.9648 1.3947 8.2014
SK-MEL-3 GDSC1; GDSC2; CTRP2 9.7464 33.2672 -5.3659 24.9785
EquiPSC Line K2 GDSC1; GDSC2 3.6054 15.9148 -2.7398 29.1932
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC2 -3.858 2.9064 -4.4042 64.4155
KYSE-50 GDSC1; GDSC2 -2.6969 1.5448 -2.8606 58.8758
TE-12 GDSC1; GDSC2 -0.5201 5.9809 -1.8089 42.1881
ESO-51 GDSC2 -0.1747 2.8271 -0.3712 35.9905
OACM5.1 C GDSC2 0.6316 6.4727 -0.8208 33.5937
KYSE-220 GDSC1; GDSC2 1.003 6.9821 -0.6754 31.3718
FLO-1 GDSC2 2.7635 5.8386 1.5725 12.7979
HCE-4 GDSC1; GDSC2 2.9001 8.2903 0.478 18.7721
SK-GT-4 GDSC2 4.8377 7.7418 2.211 3.6563
KYAE-1 GDSC2 5.5086 7.1877 2.7707 0.4266
ESO-26 GDSC2 5.5886 17.0816 -1.7724 21.3984
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 4.2913 6.7965 2.3108 4.0699
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB(TU)1 GDSC1; GDSC2 -4.8281 -0.6541 -4.8794 75.8379
IMR-32 CTRP2 -4.425 5.1253 -5.3121 59.0549
SK-N-BE(2)-M17 GDSC1; GDSC2 -3.6251 6.6821 -5.3838 59.4773
NH-6 CTRP2 -3.0128 3.2429 -3.3304 53.1837
SK-N-SH GDSC1; GDSC2; CTRP2 -2.7712 3.3499 -3.0893 51.8063
NH-12 GDSC1; GDSC2 -2.4781 3.2044 -2.9761 56.0924
SJNB-10 GDSC1; GDSC2 -2.263 3.8928 -2.9381 54.2874
CHP-212 GDSC1; GDSC2; CTRP2 -2.1217 2.8975 -2.3119 47.905
MHH-NB-11 GDSC1; GDSC2; CTRP2 -2.0056 3.2005 -2.2358 47.2142
SK-N-MC-IXC GDSC1; GDSC2 -1.9177 2.8708 -2.2796 52.0997
SK-N-DZ GDSC1; GDSC2; CTRP2 -1.87 5.665 -2.6797 46.861
KP-N-SI9s CTRP2 -1.8072 4.2315 -2.2277 46.1833
SiMa GDSC1; GDSC2; CTRP2 -1.7609 2.8186 -1.9143 45.5897
LA-N-6 GDSC1; GDSC2 -1.46 10.8367 -4.906 49.1575
SK-N-FI GDSC1; GDSC2; CTRP2 -1.4019 4.6035 -1.8753 43.8148
NB69 GDSC1; GDSC2 -1.1326 7.3787 -3.033 46.9967
TGW GDSC1; GDSC2 -1.0442 3.7544 -1.5678 44.9695
SJNB-14 GDSC1; GDSC2 -0.5655 11.6156 -4.3859 45.3801
KP-N-RT-BM-1 GDSC2 -0.3109 3.6672 -0.7421 38.2056
SJNB-17 GDSC2 -0.3088 4.1576 -0.8965 38.7112
NB1 GDSC1; GDSC2; CTRP2 -0.0749 2.8754 -0.133 34.2954
SJNB-13 GDSC1; GDSC2 -0.0267 5.2813 -1.0064 37.4934
CHP-126 GDSC1; GDSC2; CTRP2 0.005 4.7953 -0.3893 34.7967
SJNB-6 GDSC1; GDSC2 0.1851 4.1886 -0.3719 34.0572
KP-N-YS GDSC1; GDSC2 0.28 2.4393 0.1949 30.9514
GI-ME-N GDSC1; GDSC2 0.4219 12.7483 -3.9827 41.3656
SK-N-BE(2) CTRP2 0.4276 8.1115 -1.0691 35.1095
Kelly GDSC1; GDSC2; CTRP2 0.5482 5.3854 0.0403 31.6204
IMR-5 GDSC1; GDSC2 0.6788 4.011 0.2237 28.8549
SJNB-5 GDSC1; GDSC2 1.1727 9.026 -1.4726 33.4238
GOTO GDSC1; GDSC2 1.4213 4.9821 0.6405 23.3442
SJNB-7 GDSC1; GDSC2 1.8076 11.6229 -2.1495 33.0134
KP-N-YN GDSC1; GDSC2; CTRP2 1.8999 10.6652 -0.6801 29.5851
SJNB-12 GDSC1; GDSC2 2.4416 7.003 0.7046 19.0605
SK-N-AS GDSC1; GDSC2; CTRP2 3.0075 11.4782 0.0045 24.6013
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-245 CTRP2 0.1122 18.8898 -6.3216 42.9667
HuH-28 CTRP2 1.3661 6.1274 0.6898 26.8562
SNU-1079 CTRP2 1.8733 4.0461 1.7963 21.388
SNU-478 CTRP2 2.0848 10.8422 -0.5806 28.7926
SNU-1196 CTRP2 2.8115 9.6931 0.6714 22.8497
HuCC-T1 GDSC1; GDSC2; CTRP2 4.6908 8.0268 3.2492 8.2568
SNU-308 CTRP2 5.2432 8.6888 3.3851 6.5994
SNU-869 CTRP2 6.5674 12.4149 2.5383 7.897
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MCF-7 GDSC1; GDSC2; CTRP2; CTRP1 -2.5588 7.145 -3.905 50.4846
EFM-192A GDSC1; GDSC2 -2.0411 1.0834 -2.1051 53.5894
HCC2157 GDSC1; GDSC2 -1.2955 6.8741 -2.9909 47.8558
COLO 824 GDSC1; GDSC2 -0.0889 5.1803 -1.0328 37.9085
DU4475 GDSC1; GDSC2; CTRP2 0.1169 2.9555 0.0611 33.0121
MDA-MB-468 GDSC1; GDSC2; CTRP2 0.3685 3.1489 0.3072 31.3557
HCC1187 GDSC1; GDSC2 0.6328 2.3205 0.5878 27.212
HCC1599 GDSC1; GDSC2 0.7117 2.8589 0.5851 26.8426
HMC-1-8 CTRP2 1.1635 7.1969 0.0746 29.5246
CAL-51 GDSC1; GDSC2; CTRP2 1.3117 5.2295 0.9188 26.2274
HCC1569 GDSC1; GDSC2 1.5449 5.2056 0.6722 22.6544
MFM-223 GDSC1; GDSC2 1.5845 3.4262 1.3963 18.4307
BT-549 GDSC1; GDSC2 1.961 5.6787 0.8797 19.8288
Hs 578T GDSC1; GDSC2; CTRP2 2.3015 4.9903 2.0656 19.0967
MDA-MB-361 GDSC1; GDSC2; CTRP2 2.4576 9.3133 0.4997 24.3782
MDA-MB-157 GDSC1; GDSC2; CTRP2 2.7341 7.6622 1.5256 19.9012
HCC1395 GDSC1; GDSC2; CTRP2 2.7882 5.9139 2.2999 16.7954
Evsa-T GDSC1; GDSC2 3.0426 5.2277 2.1273 8.4159
OCUB-M GDSC1; GDSC2 3.2681 10.57 -0.3471 21.7375
KPL-1 CTRP2 3.4225 16.7261 -2.1976 29.529
CAL-120 GDSC1; GDSC2; CTRP2 3.6319 5.6142 3.3169 10.5508
CAL-148 GDSC1; GDSC2; CTRP2 3.8133 8.4874 2.2136 14.4876
MDA-MB-231 GDSC1; GDSC2; CTRP2 4.0393 9.7448 1.8117 15.5827
Hs 578Bst CTRP2 4.0501 8.9591 2.2072 13.9667
HCC1500 GDSC1; GDSC2; CTRP2 4.0849 8.1028 2.6569 12.0494
EFM-19 GDSC1; GDSC2 4.2476 10.1192 0.6606 13.8905
HCC1806 GDSC1; GDSC2; CTRP2 4.4991 8.6203 2.7838 10.6041
MDA-MB-330 GDSC1; GDSC2 4.5303 11.1681 0.3547 14.8104
ZR-75-1 CTRP2 4.543 16.7128 -1.2127 24.6906
BT-20 GDSC1; GDSC2; CTRP2 4.5908 8.4195 2.9654 9.6528
HCC1954 GDSC1; GDSC2; CTRP2 4.6337 7.6659 3.3774 7.842
BT-483 GDSC1; GDSC2 4.7367 8.5929 1.7518 6.4747
AU565 GDSC1; GDSC2; CTRP2 4.7689 8.6519 3.0062 9.1114
MDA-MB-175-VII GDSC1; GDSC2 5.1674 8.1557 2.2145 3.1241
MRK-nu-1 GDSC1; GDSC2 5.2179 10.7476 1.0455 9.5168
JIMT-1 GDSC1; GDSC2; CTRP2 5.2505 8.9469 3.2621 7.102
HCC1143 GDSC2; CTRP2 5.2615 10.377 2.5568 10.0226
HCC202 GDSC1; CTRP2 5.3101 7.0339 4.2615 2.8124
BT-474 GDSC1; GDSC2; CTRP2 5.3593 7.2417 4.1959 3.0031
YMB-1-E GDSC2 5.4499 8.8761 2.0536 3.5534
HCC70 GDSC1; GDSC2 5.4626 7.1744 2.7573 0.4856
MDA-MB-453 GDSC1; GDSC2; CTRP2 5.5113 7.7722 4.0473 3.3713
MDA-MB-436 GDSC1; GDSC2 5.6351 7.8313 2.5809 0.9453
T-47D GDSC1; GDSC2; CTRP2 5.6387 13.2134 1.444 13.7778
HCC2218 GDSC1; GDSC2; CTRP2 5.7584 9.3919 3.4332 5.5118
UACC-812 GDSC1; GDSC2 5.7721 7.6019 2.723 0.4296
CAL-85-1 GDSC1; GDSC2; CTRP2 5.7747 19.8328 -1.7503 23.6882
HCC1937 GDSC1; GDSC2; CTRP2 5.9048 10.4901 3.0011 7.0569
HCC38 GDSC1; GDSC2; CTRP2 5.9142 13.0019 1.7652 12.0377
HCC1428 GDSC1; GDSC2; CTRP2 6.1294 9.8845 3.458 4.8412
ZR-75-30 GDSC1; GDSC2; CTRP2 6.2249 9.024 3.9313 2.8306
HDQ-P1 GDSC1; GDSC2; CTRP2 6.2779 16.9476 0.087 17.4544
UACC-893 GDSC1; GDSC2 6.3216 8.3501 2.6642 0.3527
SK-BR-3 CTRP2 6.5 9.9981 3.65 3.5746
CAMA-1 GDSC1; GDSC2; CTRP2 6.8529 11.9146 2.9743 5.7568
MDA-MB-415 GDSC1; GDSC2; CTRP2 7.1037 14.0491 2.1212 8.7402
HCC1419 GDSC1; GDSC2; CTRP2 7.1439 8.6264 4.5618 0.1958
BT 239 CTRP2 -3.9501 12.7297 -7.5728 54.5295
BT 482 CTRP2 -3.5258 2.0923 -3.6989 56.3621
BT 286 CTRP2 -1.6013 4.0124 -1.9547 44.86
BT 416 CTRP2 -1.5609 2.5114 -1.663 44.2186
BT 131 CTRP2 -1.3277 6.4389 -2.335 44.0845
BT147 CTRP2 -0.5964 6.9963 -1.7367 40.209
BT 271 CTRP2 -0.4164 4.4007 -0.7525 37.357
BT 330 CTRP2 0.159 7.1231 -0.9706 35.7953
BT 172 CTRP2 0.4264 7.1125 -0.68 34.1289
BT 245 CTRP2 0.4902 7.7159 -0.8447 34.3426
BT 328 CTRP2 0.4916 5.0607 0.0714 31.7113
BT 504 CTRP2 0.655 5.3824 0.1577 30.8921
BT 440 CTRP2 0.802 3.1592 0.7617 28.3987
BT 228 CTRP2 1.3482 11.9396 -1.8188 33.9433
BT 112 CTRP2 1.5019 4.4297 1.3272 24.1998
BT 340 CTRP2 1.6859 9.4837 -0.3531 29.2587
BT164 CTRP2 1.7631 6.1884 1.0967 24.2236
BT 145 CTRP2 2.1359 5.9969 1.5673 21.4115
BT 248 CTRP2 2.4122 14.3413 -1.9459 31.3689
BT 159 CTRP2 2.8018 8.9783 0.9965 21.7051
BT 444 CTRP2 2.8084 9.5726 0.7251 22.6674
BT 231 CTRP2 2.9224 18.2039 -3.3779 32.9754
BT 333 CTRP2 2.9241 11.5548 -0.1113 25.1783
BT 187 CTRP2 2.9421 13.534 -1.0585 27.8865
BT 428 CTRP2 3.1439 8.8619 1.388 19.3668
BT 232 CTRP2 3.4762 10.3153 1.0102 19.9739
BT 139 CTRP2 3.8063 14.0515 -0.5284 24.3501
BT 179 CTRP2 4.9875 8.7016 3.1682 7.9952
BT 224 CTRP2 5.374 9.8221 2.9244 8.288
BT 498 CTRP2 5.4723 14.2054 0.8154 16.428
BT 216 CTRP2 6.01 10.9833 2.8362 7.5635
BT 320 CTRP2 6.236 17.0138 0.0214 17.7424
BT 422 CTRP2 6.9522 13.1915 2.4302 7.7572
BT 359 CTRP2 7.7811 15.9396 1.6742 9.4664
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.3678 8.7604 2.5963 11.665
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -4.5316 1.6525 -4.8576 69.5662
H4 GDSC1; GDSC2 -0.2798 1.0368 -0.2828 36.1559
GB-1 GDSC1; GDSC2; CTRP2 0.0393 5.1442 -0.4454 34.8358
D283 Med GDSC1; GDSC2; CTRP2 0.5127 7.2913 -0.6556 33.7716
D-336MG GDSC2 0.5673 4.9174 -0.2321 31.5427
MOG-G-UVW GDSC1; GDSC2 0.7655 2.7349 0.6675 26.1548
A-172 GDSC1; GDSC2; CTRP2 1.1589 3.4565 1.1092 26.0532
PFSK-1 GDSC1 1.2077 9.0155 -2.5979 27.1006
D-566MG GDSC1; GDSC2 1.2495 3.4497 1.0241 21.9861
MOG-G-CCM GDSC1; GDSC2 1.3556 3.9226 0.9864 21.7164
GI-1 GDSC1; GDSC2 1.4774 5.12 0.6398 23.113
Hs 683 GDSC1; GDSC2; CTRP2 1.5457 4.4475 1.371 23.9086
KNS-60 CTRP2 1.5984 4.8662 1.3308 23.8853
KINGS-1 GDSC1; GDSC2 1.8414 9.4737 -1.0607 29.4682
D-247MG GDSC2 1.9052 3.8713 1.5974 15.8927
DK-MG GDSC1; GDSC2; CTRP2 1.935 4.9788 1.6687 21.6431
SNB-75 GDSC1; GDSC2; CTRP2 1.9547 6.3141 1.2569 23.0793
M059J GDSC1; GDSC2 2.0178 4.6178 1.415 16.4837
CAS-1 GDSC1; GDSC2; CTRP2 2.0222 4.9638 1.7679 21.0204
D-263MG GDSC1; GDSC2 2.0436 4.6557 1.4251 16.3212
SF539 GDSC1; GDSC2; CTRP2 2.053 4.3147 1.9462 20.294
AM-38 GDSC1; GDSC2 2.0725 7.32 0.2055 23.0752
SNU-1105 CTRP2 2.0747 5.5671 1.647 21.2992
SF126 GDSC1; GDSC2; CTRP2 2.1558 5.665 1.7031 20.8534
SNU-201 CTRP2 2.2128 4.793 2.019 19.5363
GaMG GDSC1; GDSC2; CTRP2; CTRP1 2.3852 4.918 2.1783 18.5146
GOS-3 CTRP2 2.4068 7.4389 1.2847 21.6944
LN-18 GDSC1; GDSC2; CTRP2 2.4643 4.858 2.2773 17.8387
M059K CTRP2 2.4713 5.4648 2.1112 18.4201
KG-1-C CTRP2 2.4816 6.2146 1.8591 19.3289
D-542MG GDSC1; GDSC2 2.5153 15.2172 -3.3106 33.575
D-423MG GDSC1; GDSC2 2.5213 7.1619 0.6997 18.8108
YH-13 GDSC1; GDSC2; CTRP2 2.5892 4.7797 2.4324 16.8997
SNU-466 CTRP2 2.7109 4.7537 2.5708 16.0303
SW1088 GDSC1; GDSC2; CTRP2 2.7132 8.3149 1.2125 21.1376
YKG-1 GDSC1; GDSC2; CTRP2 2.7834 6.3318 2.136 17.4304
SNU-489 CTRP2 2.8907 5.2154 2.6452 15.2132
LNZTA3WT4 GDSC1; GDSC2 2.9846 5.7231 1.8298 10.4696
D-245MG GDSC2 3.0437 5.5908 1.948 9.5401
SF268 GDSC1; GDSC2; CTRP2 3.0644 6.4376 2.3909 15.6766
Becker GDSC1; GDSC2; CTRP2 3.0767 7.5648 1.9182 17.4854
LN-405 GDSC1; GDSC2 3.09 7.0078 1.2823 13.5273
DBTRG-05MG GDSC1; GDSC2; CTRP2 3.1013 8.4519 1.5377 18.9001
D-502MG GDSC1; GDSC2 3.2139 5.0897 2.3465 6.4966
D-392MG GDSC1; GDSC2 3.2799 5.889 2.0032 8.4686
42-MG-BA GDSC1; GDSC2; CTRP2 3.3865 7.5853 2.2213 15.4972
KNS-81-FD GDSC1; GDSC2 3.4044 6.9505 1.5759 10.7844
U-118MG GDSC1; GDSC2; CTRP2 3.4267 9.1437 1.5286 18.1278
SF295 GDSC1; GDSC2; CTRP2 3.5128 9.6299 1.3769 18.5051
SNU-626 CTRP2 3.7517 7.6971 2.531 13.3507
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 3.7908 9.1214 1.8936 15.9019
TM-31 CTRP2 4.1653 13.3043 0.1608 21.378
SW1783 GDSC1; GDSC2; CTRP2 4.3122 12.6503 0.6153 19.4997
U-251MG GDSC1; GDSC2; CTRP2 4.4016 7.5154 3.2394 8.926
KNS-81 CTRP2 4.4165 7.9902 3.0203 9.8012
Daoy GDSC1; GDSC2; CTRP2 4.4322 9.9371 2.0709 13.6797
CCF-STTG1 CTRP2 4.4658 6.1755 3.9459 5.8705
SK-MG-1 GDSC1; GDSC2 4.5123 9.7076 1.0586 11.006
KALS-1 GDSC1; GDSC2; CTRP2 4.6052 8.2748 3.05 9.2696
ONS-76 GDSC1; GDSC2; CTRP2 4.7479 9.3984 2.6156 10.7824
Onda 11 GDSC1; GDSC2 4.7792 11.1563 0.5428 13.2204
GMS-10 CTRP2 5.0208 11.7335 1.6802 14.0363
NMC-G1 GDSC1; GDSC2; CTRP2 5.3544 18.6141 -1.4839 23.7922
T98G GDSC1; GDSC2; CTRP2 5.578 12.0055 1.9979 11.7162
U-87MG ATCC GDSC1; CTRP2 5.6127 10.9232 2.5642 9.3531
Onda 10 GDSC1; GDSC2 5.639 7.5394 2.6932 0.5761
8-MG-BA GDSC1; GDSC2; CTRP2 6.2883 13.8395 1.6356 11.8984
KNS-42 GDSC1; GDSC2; CTRP2 6.2933 12.9056 2.0999 10.0751
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 -0.9965 3.8034 -1.5307 44.5833
ETK-1 GDSC1; GDSC2 3.5621 17.3388 -3.4874 31.1358
TGBC1TKB GDSC1; GDSC2 4.3717 7.4103 2.0725 5.3233
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 -0.4341 1.994 -0.4493 36.6091
JHUEM-7 CTRP2 0.549 2.5884 0.5344 29.9977
JHUEM-1 CTRP2 1.7647 4.1928 1.6565 22.2187
AN3-CA GDSC1; GDSC2; CTRP2 1.9482 5.241 1.6098 21.8147
ESS-1 GDSC1; GDSC2; CTRP2 2.3054 5.0066 2.0655 19.085
JHUEM-3 CTRP2 2.5091 5.2441 2.2206 17.9068
RL95-2 GDSC2; CTRP2 2.6227 7.4624 1.4983 20.3038
HEC-1-B CTRP2 2.9971 8.8476 1.2504 20.2597
MFE-280 GDSC1; GDSC2 3.2886 5.8339 2.0381 8.2233
KLE GDSC1; GDSC2; CTRP2; CTRP1 3.3138 7.2684 2.2979 15.459
HEC-151 CTRP2; CTRP1 3.3554 7.1333 2.4005 14.9463
HEC-6 CTRP2 3.5484 6.2846 2.9619 12.148
MFE-296 GDSC1; GDSC2; CTRP2 3.6895 7.4735 2.5745 13.3273
EN GDSC1; GDSC2; CTRP2 3.7155 8.3377 2.1917 14.808
HEC-59 CTRP2; CTRP1 3.91 7.3479 2.8573 11.7269
HEC-1-A CTRP2 4.0801 8.1162 2.6459 12.1055
HEC-251 CTRP2 4.3271 8.7553 2.5619 11.8961
HEC-50B CTRP2 4.5177 6.9413 3.6278 7.0556
MFE-319 GDSC1; GDSC2; CTRP2 4.9143 5.751 4.5776 2.2285
HEC-265 CTRP2 5.141 6.2462 4.522 2.0162
EFE-184 CTRP2 6.5558 13.7701 1.8681 10.5594
HEC-108 CTRP2; CTRP1 8.6301 17.2213 1.6339 8.5554
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 4.2234 6.3126 3.6485 7.7588
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB1047-RCC GDSC1; GDSC2 -0.0297 6.0605 -1.327 38.4479
KTCTL-13 GDSC2 0.2134 4.9169 -0.6086 34.8564
LB996-RCC GDSC1; GDSC2 0.6407 5.9535 -0.5846 32.658
NCC010 GDSC2 0.7155 3.2223 0.504 27.2479
TK-10 GDSC1; GDSC2 0.7494 9.6926 -2.1982 37.0695
LB2241-RCC GDSC1; GDSC2 1.0944 4.2909 0.5714 25.1388
A-704 GDSC1; GDSC2 1.3246 3.1796 1.1794 20.801
TUHR14TKB CTRP2 1.7303 9.7253 -0.4174 29.3187
NCC021 GDSC2 1.7983 4.3995 1.2778 18.1771
UO-31 GDSC1; GDSC2; CTRP2 1.8167 5.059 1.518 22.5454
Caki-1 GDSC1; GDSC2; CTRP2 2.2803 6.3716 1.5842 20.9317
CAL-54 GDSC1; GDSC2; CTRP2 2.7414 7.4896 1.6088 19.5644
TUHR4TKB CTRP2 3.11 8.6193 1.4683 19.1446
KTCTL-140 GDSC2 3.1447 5.9255 1.8697 9.7178
786-O GDSC1; GDSC2; CTRP2 3.2304 5.301 2.9892 12.9399
SNU-1272 CTRP2 3.3031 14.6752 -1.2894 27.6279
KMRC-2 CTRP2 3.3401 7.3171 2.2964 15.3178
KTCTL-26A GDSC2 3.394 4.9627 2.5608 4.6137
RXF 393L GDSC1; GDSC2 3.418 8.0687 1.0281 14.0627
HA7-RCC GDSC1; GDSC2 3.424 12.3187 -1.0917 24.4023
KTCTL-1M GDSC2 3.5728 6.7173 1.8285 8.7397
TUHR10TKB CTRP2 3.5875 6.4247 2.9431 12.1175
OS-RC-2 GDSC1; GDSC2; CTRP2 3.8097 7.2625 2.7916 12.1555
SW156 GDSC1; GDSC2 3.8715 8.4328 1.2088 11.7322
KMRC-1 GDSC1; GDSC2; CTRP2 3.98 7.4191 2.8848 11.3633
BFTC-909 GDSC1; GDSC2; CTRP2 4.022 7.574 2.8517 11.3986
ACHN GDSC1; GDSC2; CTRP2 4.0817 7.5229 2.9334 10.9232
VMRC-RCW GDSC1; GDSC2; CTRP2 4.1038 10.5951 1.4509 16.8564
SN12C GDSC1; GDSC2 4.2708 6.6169 2.3822 3.6897
SW13 GDSC1; GDSC2 4.3075 8.2064 1.6443 8.0382
A-498 GDSC1; GDSC2; CTRP2 4.375 8.0246 2.9653 10.1214
VMRC-RCZ GDSC1; GDSC2; CTRP2 4.4479 10.1807 1.9637 14.0794
KTCTL-21 GDSC2 4.4513 9.0746 1.3239 9.6125
BB65-RCC GDSC1; GDSC2 4.8667 15.7388 -1.6508 22.6409
769-P GDSC1; GDSC2; CTRP2 5.5029 11.9629 1.9595 12.0074
KTCTL-195 GDSC2 5.5238 7.4553 2.6774 0.6927
KMRC-20 GDSC1; GDSC2; CTRP2 5.8121 12.3154 2.0272 11.1808
Caki-2 CTRP2 5.8706 13.9783 1.246 14.1072
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 6.8004 14.8829 1.5118 11.5992
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KM12 GDSC1; GDSC2; CTRP2; CTRP1 -3.0028 0.2 -3.0143 53.6131
SK-CO-1 GDSC2; CTRP2 -2.766 8.0917 -4.4699 51.3028
SW48 GDSC1; GDSC2; CTRP2 -2.2868 4.2504 -2.7543 49.0135
SNU-C1 GDSC1; GDSC2; CTRP2 -2.236 5.1292 -2.9242 48.7915
COLO 320HSR GDSC1; GDSC2 -2.2292 9.0746 -4.8977 52.4837
SW948 GDSC1; GDSC2; CTRP2; CTRP1 -1.7022 3.1667 -1.9025 45.3314
SNU-175 GDSC2; CTRP2; CTRP1 -1.4185 3.9635 -1.7439 43.7405
LS513 GDSC1; GDSC2; CTRP2 -1.2325 5.2707 -1.8689 43.0457
GP5d GDSC1; GDSC2 -1.2173 10.4741 -4.497 47.9823
COLO 320 CTRP2; CTRP1 -1.0278 11.1497 -3.8597 44.4213
COLO205 GDSC1; GDSC2; CTRP2 -0.95 2.0909 -0.9859 40.0424
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 -0.5107 8.835 -2.3471 40.9245
NCI-H716 GDSC1; GDSC2; CTRP2 -0.3654 2.7365 -0.4252 36.2317
GP2d CTRP2 -0.1493 5.0889 -0.6359 36.0481
NCI-H508 GDSC2; CTRP2; CTRP1 0.6436 13.9172 -3.4308 38.7849
T84 GDSC1; GDSC2; CTRP2 0.8581 5.3904 0.3769 29.5138
LS1034 GDSC1; GDSC2; CTRP2 0.8906 7.3378 -0.2707 31.4443
CL-34 CTRP1 1.0947 23.8519 -7.8161 51.1097
SNU-1040 GDSC2; CTRP1 1.2187 4.6563 0.9706 33.7321
C2BBe1 GDSC1; GDSC2; CTRP2 1.2885 10.0305 -1.0015 32.2113
CaR-1 GDSC1; GDSC2 1.3952 4.9177 0.6404 23.3779
HCT 15 GDSC1; GDSC2; CTRP2 1.4677 4.7273 1.2228 24.6733
CCK-81 GDSC1; GDSC2; CTRP2 1.6779 11.2782 -1.185 31.5408
DiFi GDSC2 1.7706 9.3239 -1.0531 29.6284
SNU-407 GDSC2; CTRP2 1.8331 8.4427 0.2587 26.9241
SW620 GDSC1; GDSC2; CTRP2; CTRP1 1.8341 7.7628 0.5569 25.9869
LoVo GDSC1; GDSC2; CTRP2; CTRP1 1.8358 7.721 0.5763 25.9154
SNU-283 GDSC2 1.945 22.0141 -7.1951 40.4836
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 1.9944 6.2685 1.3207 22.8037
SW1463 GDSC1; GDSC2; CTRP2 2.304 10.3404 -0.13 26.8532
LS411N GDSC1; GDSC2; CTRP2 2.3136 9.4646 0.2865 25.4875
NCI-H747 GDSC1; GDSC2; CTRP2 2.4654 14.7325 -2.0871 31.5445
CL-11 GDSC1; GDSC2; CTRP2 2.4673 8.5267 0.8686 23.0544
HCC2998 GDSC1; GDSC2 2.5706 22.5977 -6.949 38.8179
CL-40 CTRP1 2.5837 8.6308 0.9452 41.8358
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 2.5908 11.3623 -0.3286 26.7604
HT115 GDSC1; GDSC2; CTRP1 2.8358 10.5404 0.3 29.7368
SNU-C2A CTRP2 2.9445 16.8909 -2.7086 31.6832
COLO201 CTRP2 3.0683 11.2891 0.1536 23.9656
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 3.1313 7.0036 2.2276 16.2112
SW626 GDSC1; GDSC2 3.2156 11.4557 -0.8339 23.9994
SNU-61 GDSC2; CTRP2; CTRP1 3.3012 9.8687 1.0682 20.253
HCC-56 CTRP2 3.3526 8.5925 1.719 17.5674
LS180 GDSC1; GDSC2; CTRP2; CTRP1 3.4799 10.1163 1.1182 19.6346
LS123 GDSC1; GDSC2; CTRP2; CTRP1 3.5247 8.7052 1.8398 16.7479
SNU-C5 GDSC2; CTRP2; CTRP1 3.5953 8.7633 1.8802 16.4181
DLD-1 CTRP2 3.6318 7.3671 2.5665 13.503
SW1417 GDSC1; GDSC2; CTRP2 3.6554 10.8371 0.9223 19.8733
SW480 CTRP1 3.77 10.9062 1.0021 34.8977
SNU-503 CTRP2 3.8778 16.8145 -1.8391 27.6983
SNU-81 GDSC2; CTRP2; CTRP1 3.9305 8.7822 2.1897 14.3893
HCT 8 CTRP2; CTRP1 4.0126 7.0941 3.077 10.5866
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 4.451 11.0939 1.521 15.9018
SNU-C4 CTRP2; CTRP1 4.4865 7.4719 3.3475 8.3721
OUMS-23 CTRP2 4.6502 8.6996 2.8787 9.8891
SNU-C2B GDSC1; GDSC2 4.7075 17.4599 -2.6281 26.0779
SW837 GDSC1; GDSC2 4.7548 19.4409 -3.5768 28.4417
RKO GDSC1; GDSC2; CTRP2; CTRP1 4.9716 10.4063 2.3121 11.6648
SW1116 GDSC2; CTRP2 5.0269 15.0091 0.0475 19.9414
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 5.3927 12.1622 1.7815 12.9928
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 8.8846 22.2254 -0.583 15.48
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 5.2739 7.5591 2.5243 1.4862
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 -1.3641 5.5924 -2.1064 43.9617
SNU-182 CTRP2 -0.3635 5.2548 -0.9161 37.5743
Li-7 CTRP2 0.0405 4.2836 -0.2292 34.1943
SNU-886 CTRP2 0.3183 6.4213 -0.5456 34.1355
SNU-878 CTRP2 2.202 8.2888 0.7047 24.363
HuH-6 CTRP2 2.3343 6.2756 1.6784 20.4258
HuH-1 GDSC1; GDSC2; CTRP2 2.3383 7.4823 1.1951 22.2157
JHH-5 CTRP2 2.5656 16.7117 -2.965 33.0527
JHH-4 GDSC1; GDSC2; CTRP2 2.8617 5.3558 2.5705 15.5734
SNU-761 CTRP2 2.9041 12.6635 -2.5484 21.6079
SNU-398 GDSC1; GDSC2; CTRP2; CTRP1 3.1103 10.0955 0.7766 21.7862
SNU-475 GDSC1 3.211 7.4501 -0.3187 7.6633
Huh-7 GDSC1; GDSC2 3.2154 15.5085 -2.8603 30.5564
HLF CTRP2 3.3877 5.55 3.0768 12.1541
SNU-423 GDSC1; GDSC2; CTRP2 3.4771 6.6075 2.7502 13.1678
HLE GDSC1; GDSC2 3.55 6.748 1.7951 9.0105
JHH-1 GDSC1; GDSC2; CTRP2 3.7105 12.1861 0.3089 21.9075
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 3.7825 7.1205 2.8371 12.122
JHH-7 GDSC1; GDSC2 3.9327 10.4531 0.2516 16.9018
SNU-387 GDSC1; GDSC2; CTRP2 4.1344 9.456 2.0408 14.4509
Hep-G2/C3A GDSC1; GDSC2 4.1501 11.0313 0.1338 16.9159
JHH-2 GDSC1; GDSC2; CTRP2 4.2925 9.1097 2.3555 12.8205
PLC/PRF/5 CTRP2 4.8214 6.9579 3.8959 5.2759
SK-HEP-1 GDSC1; GDSC2; CTRP2 6.027 10.8579 2.9103 7.2324
JHH-6 GDSC1; GDSC2; CTRP2; CTRP1 6.5073 10.3229 3.5139 4.1678
Hep-G2 CTRP2; CTRP1 6.7746 20.9795 -1.5207 21.3789
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 225 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L32 GDSC2 -3.4448 1.9532 -3.7391 63.494
HCC1588 CTRP2 -2.8173 3.8816 -3.248 52.0014
NCI-H1341 GDSC2; CTRP2 -2.7582 3.0319 -3.0178 51.7642
ABC-1 GDSC1; GDSC2 -2.2648 4.1089 -3.0067 54.2071
LCLC-97TM1 GDSC1; GDSC2; CTRP2 -2.2575 8.9732 -4.2589 49.1531
LB647-SCLC GDSC1; GDSC2 -2.1723 3.0776 -2.6092 53.9909
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 -1.8222 3.6109 -2.1106 46.1862
Lu-135 GDSC1; GDSC2 -1.6967 3.0551 -2.0846 50.2936
NCI-H2073 CTRP1 -1.5184 3.9884 -1.8577 74.5419
NCI-H2171 GDSC1; GDSC2; CTRP2 -1.5029 0.4872 -1.5042 43.6226
COR-L311 GDSC2 -1.4553 10.0035 -4.5213 49.0846
NCI-H847 GDSC1; GDSC2 -1.448 2.629 -1.7121 48.1361
NCI-H358 GDSC1; GDSC2; CTRP2 -1.4149 5.6651 -2.1836 44.2854
COR-L303 GDSC2 -1.3618 12.3736 -5.5219 48.8646
SBC-3 GDSC1; GDSC2 -1.3565 4.4285 -2.1238 47.7463
NCI-H1975 GDSC1; GDSC2; CTRP2 -1.2827 5.7472 -2.0646 43.5475
NCI-H727 GDSC1; GDSC2; CTRP2 -1.2752 7.5735 -2.6772 44.2426
NCI-H292 GDSC1; GDSC2; CTRP2 -1.1958 8.91 -3.1065 44.3499
A-427 GDSC1; GDSC2 -1.1705 3.0571 -1.5111 45.7715
LK-2 GDSC1; GDSC2 -1.1647 0.7785 -1.1757 45.0578
LC-2/ad GDSC1; GDSC2 -1.0975 4.9377 -2.022 45.9374
HCC44 GDSC1; GDSC2; CTRP2 -0.7869 4.4545 -1.1686 39.8359
Lu-134-A GDSC1; GDSC2 -0.7675 4.7447 -1.5969 43.2287
NCI-H1437 GDSC1; GDSC2 -0.7606 16.3893 -6.8628 47.2131
NCI-H2009 GDSC1; GDSC2; CTRP2; CTRP1 -0.5584 5.2586 -1.1272 38.8841
NCI-H524 GDSC1; GDSC2; CTRP2 -0.4768 3.048 -0.5763 37.0909
Lu-99A GDSC1; GDSC2 -0.4497 8.0378 -2.6188 43.1313
NCI-H1734 GDSC1; GDSC2; CTRP2 -0.4375 5.6919 -1.1268 38.358
NCI-H526 GDSC1; GDSC2; CTRP2 -0.2597 7.3153 -1.4913 38.468
NCI-H1770 GDSC1; GDSC2 -0.167 6.3249 -1.5815 39.8086
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 -0.1265 6.0969 -0.9141 36.7396
DMS 454 CTRP2 -0.1076 11.1864 -2.937 40.3354
NCI-H2141 GDSC1; GDSC2; CTRP2; CTRP1 -0.0335 5.5473 -0.6393 35.6943
NCI-H2373 GDSC1; GDSC2 -0.0098 11.0572 -3.5814 42.4666
DV-90 CTRP2 -0.005 5.5899 -0.6243 35.4919
NCI-H2228 GDSC1; GDSC2; CTRP2 0.036 5.4191 -0.5281 35.0806
NCI-H1876 GDSC1; GDSC2; CTRP1 0.0819 3.2515 -0.0069 42.7979
NCI-H1304 GDSC1 0.093 3.7232 -0.9943 23.336
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 0.1694 5.4447 -0.3873 34.2698
NCI-H810 GDSC1; GDSC2; CTRP2 0.2068 5.8294 -0.4685 34.3092
NCI-H1963 GDSC1; GDSC2; CTRP1 0.24 3.6321 0.1096 41.5946
NCI-H2106 CTRP2 0.3021 7.2731 -0.8737 35.0566
NCI-H2869 GDSC1; GDSC2 0.3154 7.4936 -1.5991 37.4809
SCLC-21H CTRP1 0.4091 4.5257 0.1194 61.8583
IST-SL1 GDSC1; GDSC2 0.4178 2.5183 0.3302 29.5847
EBC-1 GDSC1; GDSC2; CTRP2 0.4457 1.3768 0.4457 30.6369
NCI-H187 GDSC1 0.4477 3.135 -0.3701 17.2595
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 0.4499 8.8959 -1.3639 35.7691
CPC-N GDSC1; GDSC2 0.4618 13.7577 -4.4365 41.7658
LUDLU-1 CTRP2 0.566 9.5234 -1.5166 35.6722
NCI-H2731 GDSC1; GDSC2 0.6658 5.3584 -0.3066 31.3936
DMS 273 GDSC1; GDSC2; CTRP2 0.6854 4.9145 0.3221 30.2568
NCI-H1184 CTRP2 0.7066 5.1394 0.2842 30.312
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 0.7962 2.7782 0.7804 28.4241
EKVX GDSC1; GDSC2; CTRP2 0.8267 12.7288 -2.7015 37.1189
NCI-H211 GDSC1; GDSC2; CTRP2 0.9101 6.0918 0.2085 29.8984
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 0.9145 5.8054 0.3121 29.6125
NCI-H1105 GDSC2; CTRP2; CTRP1 0.9255 6.4418 0.1069 30.239
NCI-H446 GDSC1; GDSC2; CTRP2 0.9445 2.5156 0.9399 27.3295
Lu-99 CTRP2 0.9576 5.0263 0.5893 28.4807
HCC2108 CTRP2; CTRP1 0.9693 5.6211 0.4305 29.0454
NCI-H1648 GDSC1; GDSC2 0.9748 14.7542 -4.4514 40.1369
Ms-1 GDSC1; GDSC2 1.0301 11.3704 -2.742 37.1729
SBC-1 GDSC1; GDSC2 1.0313 2.4102 0.9995 23.1464
UMC-11 GDSC1; GDSC2 1.0852 3.236 0.9038 23.3927
NCI-H596 GDSC1; GDSC2; CTRP1 1.1603 5.2636 0.7466 34.9364
NCI-H1623 GDSC1; GDSC2; CTRP2 1.1696 11.492 -1.7877 34.3943
NCI-H2286 CTRP1 1.1733 3.3124 1.138 55.203
NCI-H2405 GDSC1; GDSC2; CTRP2 1.1905 6.6143 0.3253 28.6305
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 1.221 6.1878 0.5157 27.9671
NCI-H1048 GDSC1; GDSC2 1.2265 3.382 1.0184 22.1224
RERF-LC-MS GDSC1; GDSC2; CTRP2 1.2461 4.4212 1.0512 25.972
EMC-BAC-1 GDSC2 1.2627 4.5025 0.6698 23.8671
NCI-H2227 GDSC1; GDSC2 1.2705 4.5305 0.6671 23.8463
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 1.3217 5.7504 0.7726 26.7755
NCI-H82 GDSC1; GDSC2 1.3368 3.6727 1.0504 21.4469
NCI-H209 GDSC1; GDSC2 1.3569 5.087 0.529 24.2203
NCI-H838 GDSC1; GDSC2; CTRP2 1.3747 8.2812 -0.1462 29.561
COR-L23 GDSC1; GDSC2; CTRP1 1.3901 7.352 0.2587 35.5136
A-549 GDSC1; GDSC2; CTRP2 1.4172 7.1703 0.3547 27.8367
IST-SL2 GDSC1; GDSC2 1.5022 7.219 -0.2932 27.6753
EPLC-272H GDSC1; GDSC2; CTRP2 1.5167 8.413 -0.055 28.854
COR-L279 GDSC2 1.5702 4.6965 0.9158 21.1922
NCI-H720 GDSC1; GDSC2 1.5738 2.5793 1.5542 17.6406
COLO 699 CTRP2; CTRP1 1.5907 14.0339 -2.5679 34.8032
NCI-H2810 GDSC2 1.6541 4.7844 0.9666 20.5565
LOU-NH91 GDSC1; GDSC2; CTRP2 1.6778 6.7328 0.8025 25.5234
COR-L321 GDSC2 1.6893 5.8014 0.5523 22.7243
NCI-H1781 GDSC1; GDSC2; CTRP1 1.7288 5.4495 1.311 30.2477
NCI-H1568 GDSC1; GDSC2; CTRP2 1.7296 8.6074 0.0803 27.8016
Lu-65 GDSC1; GDSC2; CTRP2 1.7329 8.4398 0.1568 27.5464
HOP-92 GDSC1; GDSC2; CTRP2 1.781 5.4575 1.3621 23.2139
NCI-H2126 CTRP2 1.7974 8.2661 0.2986 26.8959
NCI-H1930 CTRP1 1.8069 6.0467 1.1983 47.4496
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 1.8129 8.5828 0.1827 27.2953
NCI-H23 GDSC1; GDSC2; CTRP2 1.8627 5.7518 1.3561 22.9902
NCI-H1581 GDSC1; GDSC2; CTRP2 1.8664 4.3736 1.7336 21.6271
NCI-H2461 GDSC1; GDSC2 1.943 7.0619 0.2072 23.5523
HCC366 GDSC2; CTRP2 1.9505 10.5345 -0.5692 29.1318
NCI-H3255 GDSC1; GDSC2; CTRP1 1.9771 6.1559 1.3431 29.0935
NCI-H1688 GDSC1; GDSC2 2.0366 10.2915 -1.2845 29.5623
NCI-H2795 GDSC1; GDSC2 2.0477 4.1537 1.6406 15.0428
NCI-H2085 GDSC1; GDSC2; CTRP2 2.0777 5.3868 1.7072 21.0712
NCI-H1563 GDSC1; GDSC2; CTRP2 2.0808 5.4436 1.693 21.1135
LK2 CTRP2 2.0911 5.2177 1.7724 20.7943
NCI-H1993 GDSC1; GDSC2 2.1099 6.1625 0.798 19.7305
DMS 53 GDSC1; GDSC2; CTRP2 2.1444 6.549 1.3712 22.1109
SK-LU-1 GDSC1; CTRP2; CTRP1 2.1534 6.8897 1.2514 22.5995
VMRC-LCD GDSC2; CTRP2 2.2085 6.7985 1.3412 22.039
NCI-H510A GDSC1; GDSC2 2.218 5.1303 1.3886 15.8622
ChaGo-K-1 GDSC1; GDSC2; CTRP2 2.2763 7.1086 1.287 22.0487
HCC1833 CTRP2; CTRP1 2.3508 16.6418 -3.1198 33.8799
HCC4006 CTRP2; CTRP1 2.4162 6.8233 1.5559 20.7286
HCC33 GDSC1; GDSC2 2.435 14.9488 -3.2462 33.6686
HCC78 GDSC1; GDSC2; CTRP2 2.4703 9.4267 0.46 24.4801
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 2.519 6.8938 1.6303 20.0875
RERF-LC-Sq1 GDSC1; GDSC2 2.5294 6.9827 0.7953 18.2404
NCI-H2029 GDSC1; GDSC2; CTRP2 2.5858 7.4364 1.4713 20.5056
NCI-H2804 GDSC1; GDSC2 2.6488 8.3549 0.2246 20.9404
HCC95 CTRP2 2.6722 7.4049 1.5743 19.8816
HCC1438 CTRP2 2.6794 9.4687 0.6472 23.2779
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 2.7702 14.871 -1.8644 30.3488
NCI-H1092 GDSC1; GDSC2; CTRP2 2.7914 9.3588 0.8088 22.4126
NCI-H647 GDSC1; GDSC2; CTRP2 2.7937 6.6328 2.0261 17.8222
NCI-H250 GDSC2 2.8012 9.0181 0.0291 21.4226
NCI-H322M GDSC1; GDSC2 2.8207 8.3651 0.3714 19.6019
NCI-H3122 GDSC1; GDSC2 2.87 5.1372 2.0148 9.6893
SK-MES-1 GDSC1; GDSC2; CTRP2 2.8859 7.6715 1.6765 18.9214
NCI-H1836 GDSC1; GDSC2; CTRP1 2.8958 8.7493 1.2028 26.2221
DMS 114 GDSC1; GDSC2; CTRP2 2.8988 6.071 2.3599 16.2549
NCI-H1436 GDSC1; GDSC2 2.9239 5.7456 1.7642 11.0761
NCI-H69 GDSC1; GDSC2; CTRP2 2.9266 7.0814 1.9768 17.6524
NCI-H2591 GDSC1; GDSC2 2.9316 5.0924 2.0935 8.9908
COR-L95 GDSC1; GDSC2; CTRP2 2.9882 12.7468 -0.6308 26.5853
COR-L88 GDSC1; GDSC2; CTRP2 3.0282 6.0455 2.5079 15.3277
RERF-LC-KJ GDSC1; GDSC2; CTRP1 3.0439 8.385 1.5185 24.3591
NCI-H2803 GDSC1; GDSC2 3.0577 10.7165 -0.5978 23.496
HOP-62 GDSC1; GDSC2; CTRP2 3.1009 8.8068 1.3717 19.5372
NCI-H290 GDSC1; GDSC2 3.1497 8.4729 0.6015 17.3071
NCI-H345 GDSC1; GDSC2 3.1706 7.2174 1.2467 13.4958
NCI-H64 GDSC1; GDSC2 3.1708 5.5487 2.0802 8.3108
NCI-H748 GDSC1; GDSC2 3.1865 7.8586 0.9397 15.2714
NCI-H1838 GDSC1; GDSC2; CTRP2 3.1904 7.7992 1.9269 17.1584
NCI-H520 GDSC1; GDSC2; CTRP2 3.1987 6.9377 2.3198 15.5929
SW1271 GDSC1; GDSC2; CTRP2 3.2195 9.7941 1.0183 20.5676
HCC1171 CTRP2 3.2262 11.4426 0.2274 23.3326
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 3.2407 8.5315 1.645 18.209
SW1573 GDSC1; GDSC2 3.2877 10.7689 -0.4302 22.0539
NCI-H2722 GDSC1; GDSC2 3.291 8.3271 0.7935 15.7982
NCI-H1703 GDSC1; GDSC2; CTRP2 3.3562 7.7617 2.1101 16.0151
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 3.4147 12.467 -0.0911 23.9752
NCI-H1355 GDSC1; GDSC2; CTRP2 3.4393 10.6311 0.822 20.7503
COR-L105 GDSC1; GDSC2; CTRP2 3.4494 11.7839 0.2678 22.659
PC-14 GDSC1; GDSC2; CTRP2 3.4688 7.1986 2.4799 14.2597
NCI-H1792 GDSC1; GDSC2; CTRP2 3.4888 12.659 -0.126 23.8492
Sq-1 CTRP2; CTRP1 3.5342 8.457 1.9671 16.221
NCI-H2818 GDSC1; GDSC2 3.5368 6.4421 1.9371 8.156
NCI-H2066 GDSC2 3.5417 14.397 -2.0336 27.3355
Calu-1 CTRP2 3.5432 8.3438 2.0221 15.9027
NCI-H1944 GDSC1; GDSC2; CTRP2 3.574 13.3632 -0.396 24.4857
NCI-H1693 GDSC1; GDSC2; CTRP2 3.6474 6.4571 2.991 11.7708
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 3.6737 10.7507 0.9897 19.6526
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 3.7376 6.3117 3.1527 10.9812
NCI-H2087 GDSC1; GDSC2; CTRP2 3.8074 12.6004 0.1918 22.0775
NCI-H1666 GDSC1; GDSC2; CTRP2 3.819 8.9365 2.002 15.3262
RERF-LC-Ad2 CTRP2 3.8191 5.9025 3.404 9.6958
HCC2279 CTRP2 3.8272 13.8856 -0.4274 23.9995
NCI-H2170 GDSC1; GDSC2; CTRP2 3.8935 9.1048 1.9902 15.201
NCI-H1373 CTRP2 3.8966 10.0284 1.5413 16.972
Lu-139 GDSC1; GDSC2 3.9356 6.813 2.0576 6.3833
NCI-H2595 GDSC1; GDSC2 3.988 8.329 1.3495 10.5891
NCI-H889 CTRP2 4.0025 9.0493 2.1189 14.4323
NCI-H1869 GDSC1; CTRP2 4.063 11.9786 0.7289 19.6433
NCI-H2291 GDSC1; GDSC2; CTRP2 4.1257 8.1742 2.6606 11.9406
NCI-H1155 GDSC1; GDSC2; CTRP2 4.1672 8.0548 2.7576 11.4467
NCI-H146 GDSC2 4.1672 6.3278 2.4515 3.4831
LCLC-103H GDSC1; GDSC2; CTRP2 4.1725 6.2954 3.5986 8.0001
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 4.1816 12.231 0.7178 19.4875
NCI-H1299 GDSC1; GDSC2; CTRP2 4.1908 14.6661 -0.4951 23.396
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 4.238 10.2891 1.7317 15.5346
IA-LM GDSC1; GDSC2; CTRP2 4.2759 6.7444 3.492 8.1776
EMC-BAC-2 GDSC2 4.2896 9.1504 1.1695 10.9016
Calu-3 GDSC1; GDSC2; CTRP2 4.2978 9.3996 2.2171 13.3748
RERF-LC-Ad1 CTRP2 4.3054 6.2617 3.747 7.0703
PaCa-3 GDSC1; GDSC2 4.3546 7.1879 2.167 4.7958
NCI-H522 GDSC1; GDSC2; CTRP2 4.3582 8.6404 2.6467 11.4776
LC-1/sq GDSC1; GDSC2 4.3632 13.2927 -0.8245 20.7448
NCI-H226 GDSC1; GDSC2; CTRP2 4.3655 10.4927 1.7357 15.1675
NCI-H1339 CTRP2 4.4065 9.7349 2.1484 13.4199
NCI-H835 GDSC2 4.4246 9.0606 1.3116 9.7471
RERF-LC-A1 CTRP2 4.4585 9.315 2.4031 12.2659
NCI-H1650 GDSC1; GDSC2; CTRP2 4.5273 8.5983 2.82 10.3935
NCI-H196 GDSC1; GDSC2; CTRP2 4.5328 8.3305 2.9577 9.8085
T3M-10 CTRP2; CTRP1 4.6084 7.3823 3.5033 7.4563
NCI-H1915 GDSC1; GDSC2; CTRP2; CTRP1 4.6856 9.4038 2.568 11.1874
NCI-H513 GDSC1; GDSC2 4.6879 8.1914 1.9097 5.6487
NCI-H1573 GDSC1; GDSC2; CTRP2 4.6939 10.3478 2.0953 13.0323
NCI-H661 GDSC1; GDSC2; CTRP2 4.7282 8.4676 3.0627 8.959
NCI-H2369 GDSC1; GDSC2 4.7699 9.913 1.1411 9.9437
NCI-H740 GDSC2 4.7891 11.3474 0.4565 13.6525
COR-L51 CTRP1 4.8691 13.9283 0.4651 31.8671
NCI-H2135 GDSC1; GDSC2 4.89 11.7711 0.3222 14.1085
NCI-H2444 GDSC1; GDSC2; CTRP2 4.9509 9.0212 1.6885 5.2259
Lu-165 GDSC1; GDSC2 4.9875 12.8378 -0.1294 16.1021
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 5.1466 13.0236 1.1494 15.8988
HCC1359 CTRP1 5.2665 7.2988 4.1069 7.7532
BEN GDSC1; GDSC2; CTRP2 5.2713 6.7093 4.3926 2.3317
MOR/CPR CTRP2 5.3741 11.2324 2.2207 11.1916
NCI-H322 CTRP2 5.3788 12.0306 1.8259 12.77
NCI-H1651 GDSC1; GDSC2; CTRP2 5.5199 8.411 3.739 4.6347
DMS 79 GDSC1; GDSC2; CTRP2 5.6737 11.9766 2.0877 11.1835
SHP-77 GDSC1; GDSC2; CTRP2 5.6961 8.7902 3.683 4.5807
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 5.788 12.1599 2.0962 11.0201
NCI-H1395 CTRP2 5.8614 17.1662 -0.3499 19.5996
LC-1/sq-SF CTRP2 5.8904 8.7524 3.8393 3.6466
NCI-H2347 GDSC1; GDSC2 6.1264 8.3971 2.5719 0.6655
NCI-H2196 GDSC1; GDSC2; CTRP2 6.3148 10.8365 3.1265 5.9095
HCC1195 CTRP2; CTRP1 6.482 18.372 -0.452 18.8555
Calu-6 GDSC1; GDSC2; CTRP2 6.5085 13.6269 1.9038 10.4968
SBC-5 GDSC1; GDSC2; CTRP2 6.7149 15.8909 0.9426 13.7653
KNS-62 GDSC2; CTRP2 6.9638 8.6117 4.4961 0.3723
NCI-H650 GDSC1; GDSC2; CTRP2 7.2261 16.9827 0.7814 13.5119
NCI-H1793 GDSC1; GDSC2; CTRP2 8.1137 17.7537 1.0299 11.3183
HCC2935 CTRP2; CTRP1 8.2604 15.8717 2.0308 7.5864
Hs 888.Lu CTRP2 2.5647 6.3411 1.8996 18.9408
⏷ Show the Full List of 225 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 5.6304 7.7819 2.5979 0.8886
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 1.0535 2.6489 1.0476 26.6074
H-STS CTRP2 1.2878 4.5223 1.0746 25.7583
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 1.0629 3.1513 1.0345 26.6209
OVKATE GDSC1; GDSC2; CTRP1 0.8857 5.0972 0.494 37.0995
RMUG-S CTRP1 1.3761 7.3637 0.2391 51.479
A2780 GDSC1; GDSC2; CTRP2; CTRP1 1.6463 4.7666 1.4102 23.5292
OV7 CTRP2; CTRP1 1.7981 6.1042 1.1685 23.9334
COV362 CTRP2; CTRP1 1.8271 6.7276 0.9685 24.5656
Caov-3 GDSC1; GDSC2; CTRP2; CTRP1 1.8528 4.733 1.6433 22.0629
OAW28 GDSC1; GDSC2; CTRP2 2.0901 8.2303 0.6157 24.9861
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 2.2177 5.5717 1.8044 20.3751
SNU-119 CTRP2 2.429 9.18 0.5326 24.3417
COV434 CTRP2; CTRP1 2.8643 9.5376 0.8035 22.3127
OVTOKO GDSC1; GDSC2; CTRP2 2.8827 6.7923 2.0536 17.4734
IGROV-1 GDSC1; GDSC2; CTRP2; CTRP1 3.1028 6.3707 2.4637 15.3709
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 3.3484 8.9337 1.5606 18.2698
OVCAR-8 GDSC1; GDSC2; CTRP2; CTRP1 3.3546 6.0602 2.8544 13.1754
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 3.4171 6.6569 2.6726 13.7131
Caov-4 GDSC1; GDSC2 3.4192 19.2104 -4.5414 33.6075
TOV-21G GDSC1; GDSC2; CTRP2 3.4246 6.2509 2.8462 12.9325
DOV13 GDSC2; CTRP2 3.4489 7.7412 2.2118 15.3785
OVCAR-5 GDSC1; GDSC2; CTRP2 3.4665 7.138 2.5049 14.1663
JHOS-4 GDSC2; CTRP1 3.4759 18.2426 -2.8946 35.4613
ES-2 GDSC1; GDSC2 3.6549 5.849 2.324 5.4129
JHOM-1 CTRP2; CTRP1 3.6957 6.0816 3.2059 10.885
TOV-112D GDSC1; GDSC2; CTRP2 3.8783 10.3508 1.3661 17.6919
MCAS CTRP2 3.8856 6.9468 3.0131 11.0736
OAW42 GDSC1; CTRP2; CTRP1 3.9507 6.0264 3.4956 9.0707
OVCAR-3 GDSC1; GDSC2 4.0327 15.7201 -2.2952 26.8199
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 4.2051 8.0401 2.8082 11.234
ONCO-DG-1 CTRP2 4.3044 8.7631 2.5373 12.0472
HEY A8 CTRP2 4.3729 9.3986 2.2851 12.9341
OV56 GDSC2; CTRP2 4.4383 5.2789 4.3067 4.5137
SK-OV-3 GDSC1; GDSC2; CTRP2 4.6804 10.9514 1.7823 14.3187
SNU-840 CTRP2; CTRP1 4.8353 10.6375 2.0811 12.8779
JHOS-2 GDSC2; CTRP2 4.8461 9.4395 2.6795 10.3185
SNU-8 CTRP2 4.9816 12.8412 1.0936 16.3659
COV318 CTRP1 4.9817 8.1421 3.4525 14.6341
OVK18 GDSC2; CTRP2; CTRP1 5.0073 11.3949 1.8478 13.4722
EFO-21 GDSC1; GDSC2; CTRP2 5.1718 9.1634 3.0901 7.9691
Kuramochi GDSC1; GDSC2; CTRP2 5.199 10.0164 2.686 9.6044
OVMANA CTRP1 5.2898 10.2627 2.6468 19.5041
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 5.2957 7.0292 4.2634 2.9107
COV644 CTRP2; CTRP1 5.4657 11.3049 2.2681 10.9052
OC 314 GDSC1; GDSC2; CTRP2 5.4739 11.1558 2.3388 10.5263
JHOC-5 CTRP2; CTRP1 6.3523 11.528 2.8286 7.1309
OVSAHO CTRP2 6.9609 13.1933 2.4353 7.7247
ES2 CTRP2 6.9955 8.3939 4.5886 0.1932
OVISE GDSC1; GDSC2; CTRP2 8.3158 16.1634 1.9173 7.8667
FU-OV-1 GDSC1; GDSC2; CTRP2 9.0068 24.3587 -1.5429 17.9298
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 1.4451 2.5146 1.4445 23.9808
Yamato-SS CTRP2 1.7868 5.3447 1.403 23.049
Rh41 GDSC1; GDSC2; CTRP2 -4.633 -0.887 -4.6446 64.0239
MFH-ino GDSC1; GDSC2 -3.788 0.757 -3.9169 67.3451
Rh30 GDSC1; GDSC2 -2.3338 2.1153 -2.5677 55.6745
Tm87-16 CTRP2 -2.1295 1.9311 -2.2042 47.869
G-401 GDSC1; GDSC2; CTRP2 -1.6595 5.7711 -2.4824 45.7157
TE 441.T GDSC1; GDSC2; CTRP2 -1.5802 6.1128 -2.5029 45.3744
EW-8 GDSC1; GDSC2 -1.4887 1.2425 -1.5395 48.3329
MES-SA GDSC1; GDSC2; CTRP2 -0.0667 2.6218 -0.1037 34.1725
STS-0421 GDSC1; GDSC2 0.0727 2.3066 -0.0073 32.9996
Rh18 CTRP2 0.8561 6.8684 -0.128 31.1282
SW982 GDSC1; GDSC2; CTRP2 1.0739 3.2385 1.0395 26.5674
Hs 633.T GDSC1; GDSC2 1.5134 5.5561 0.4855 23.7979
G-402 GDSC1; GDSC2; CTRP2 1.6068 5.344 1.2069 24.2995
RD GDSC1; GDSC2; CTRP2 1.6167 9.9959 -0.6546 30.3216
TTC-709 CTRP2 1.6306 3.568 1.5946 22.8644
VA-ES-BJ GDSC1; GDSC2 2.1195 8.939 -0.5424 26.4038
TE 617.T CTRP2 2.2986 8.052 0.9079 23.3729
KYM-1 GDSC1; GDSC2; CTRP2 2.3232 6.2039 1.6934 20.4015
BT-16 CTRP2 2.9487 6.7713 2.1314 16.9941
SK-LMS-1 GDSC1; GDSC2; CTRP2 2.986 5.5862 2.6298 14.9887
A-204 GDSC1; GDSC2; CTRP2 3.3506 8.5766 1.7245 17.5509
Hs 729.T CTRP2 3.4769 9.722 1.2984 18.8909
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 3.6869 7.8065 2.4232 14.0239
GCT GDSC1; GDSC2; CTRP2 4.0568 9.7362 1.832 15.4629
SK-UT-1 GDSC1; GDSC2; CTRP2 4.2879 6.6418 3.5523 7.9029
SW684 GDSC1; GDSC2 5.0031 6.1461 2.9512 0.2021
BT-12 CTRP2 5.4414 10.2884 2.7454 8.9104
SW872 GDSC1; GDSC2 5.7902 9.2388 2.0791 2.9639
RKN GDSC1; GDSC2; CTRP2; CTRP1 5.864 9.0902 3.6685 4.4568
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.0208 8.1476 4.2114 2.0049
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1; GDSC2; CTRP2 0.8572 3.896 0.7294 28.3275
IST-Mes1 GDSC1; GDSC2; CTRP2 1.427 4.9284 1.1277 25.1349
NCI-H28 GDSC1; GDSC2; CTRP2 1.9031 6.9258 0.967 24.2788
NCI-H2052 GDSC1; GDSC2; CTRP2 2.9451 8.329 1.4389 19.6783
JL-1 CTRP2 3.1457 8.9387 1.3536 19.4935
MSTO-211H GDSC1; GDSC2; CTRP2 3.4962 5.0516 3.3528 10.8161
NCI-H2452 GDSC1; GDSC2; CTRP2 3.9187 8.705 2.2083 14.2632
ACC-MESO-1 CTRP2 3.9302 6.2992 3.3508 9.6094
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2; CTRP2 -3.4546 5.413 -4.3341 54.8259
22Rv1 GDSC1; GDSC2; CTRP2 2.6104 12.2893 -0.7636 27.9136
LNCaP clone FGC GDSC1; GDSC2; CTRP2 3.9407 6.9591 3.0622 10.7389
PC-3 GDSC1; GDSC2 3.9871 7.27 1.8711 7.4111
NCI-H660 GDSC2; CTRP2 4.106 14.9396 -0.7054 24.203
PaCa-3 CTRP2; CTRP1 4.4656 7.946 3.0953 9.4647
DU145 GDSC1; GDSC2; CTRP2 4.4695 8.4855 2.824 10.501
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 1.5431 3.7347 1.4852 23.5218
A-253 GDSC1; GDSC2; CTRP2 5.5045 9.9637 2.9569 7.9191
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -2.2124 1.2966 -2.3093 55.0572
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RERF-GC-1B GDSC1; GDSC2 -3.7694 2.7008 -4.2567 64.2548
GSS CTRP2 -1.2594 5.4628 -1.9538 43.2899
ECC10 GDSC1; GDSC2; CTRP2 -1.1039 5.3901 -1.7629 42.3199
SNU-16 GDSC1; GDSC2; CTRP2 -0.3958 0.351 -0.3958 36.2436
SNU-620 CTRP2 0.008 1.0921 0.0079 33.5535
SNU-5 GDSC1; GDSC2 0.1862 1.1672 0.1855 31.4684
IM95 GDSC1; GDSC2; CTRP2 0.2076 6.389 -0.6541 34.8157
HGC-27 GDSC1; GDSC2; CTRP2 0.7214 3.5569 0.6339 29.0947
HuG1-N CTRP2 0.7356 16.4286 -4.5431 39.8688
SNU-719 CTRP2 0.7712 12.8585 -2.8167 37.468
HSC-39 GDSC1; GDSC2 0.8626 2.0928 0.8489 24.7469
GCIY GDSC1; GDSC2 1.2002 30.7721 -12.209 44.7642
OCUM-1 GDSC1; GDSC2; CTRP2 1.6162 10.376 -0.8287 30.7971
Hs 746.T GDSC2; CTRP2 1.6414 4.3521 1.4942 23.1756
KATO III GDSC2; CTRP2 2.013 5.1664 1.702 21.2854
SNU-668 CTRP2 2.587 8.2402 1.1186 21.8218
Fu97 GDSC1; GDSC2; CTRP2 2.913 5.6197 2.5392 15.5387
SNU-216 CTRP2 3.0192 9.2388 1.0885 20.8082
MKN45 GDSC1; GDSC2; CTRP2 3.0436 7.0431 2.1142 16.8067
SCH GDSC1; GDSC2 3.1421 4.8409 2.4078 6.3324
TMK-1 GDSC1; GDSC2 3.151 15.5957 -2.958 30.9763
MKN1 GDSC1; GDSC2; CTRP2 3.2706 6.8924 2.4136 15.0352
NUGC-4 GDSC1; GDSC2; CTRP2 3.3156 9.8549 1.081 20.0995
SNU-1 GDSC1; GDSC2; CTRP2 3.5506 11.7529 0.3763 22.0521
RF-48 GDSC1; GDSC2 3.8722 11.2494 -0.1931 19.2661
LMSU CTRP2 4.0943 7.4595 2.9759 10.7196
MKN28 GDSC1; GDSC2 4.1645 12.7593 -0.7143 20.8048
ECC12 GDSC2; CTRP2 4.2027 6.5664 3.504 8.3062
TGBC11TKB GDSC1; GDSC2 4.2231 8.2046 1.5848 8.5935
NUGC-3 GDSC1; GDSC2; CTRP2 4.5064 9.2465 2.4797 11.8481
MKN7 GDSC1; GDSC2; CTRP2 4.6234 8.9508 2.7301 10.5643
AGS GDSC1; GDSC2; CTRP2; CTRP1 4.9108 10.8698 2.0291 12.9367
SNU-601 CTRP2 4.9589 12.7985 1.0959 16.4028
SH-10-TC CTRP2 5.0387 7.3857 3.869 4.9517
SK-GT-2 GDSC2 5.3893 7.5658 2.5757 1.1624
MKN74 CTRP2; CTRP1 5.5621 14.1075 0.9469 15.8482
KE-39 CTRP2 5.5689 17.8158 -0.9096 21.8131
23132/87 GDSC1; GDSC2; CTRP2 5.6445 10.6632 2.7181 8.6633
GSU CTRP2 6.0348 6.8731 4.766 0.1828
NCI-N87 GDSC1; CTRP2 6.8569 12.8909 2.5096 7.5827
SNU-1077 CTRP2 2.5869 6.4993 1.8612 19.0238
SNU-685 CTRP2 3.8835 6.9364 3.0158 11.068
SNG-M GDSC1; GDSC2; CTRP2; CTRP1 4.1389 6.8375 3.3214 9.2879
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1; GDSC2 -0.8343 6.4479 -2.3307 44.7388
FTC-238 CTRP2 1.5703 4.2736 1.4322 23.6171
B-CPAP GDSC1; GDSC2; CTRP2 1.8596 7.679 0.6132 25.6514
TT GDSC1; GDSC2; CTRP2 2.1508 7.6296 0.9376 23.6773
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 2.1517 6.4221 1.4275 21.882
BHT-101 GDSC1; GDSC2; CTRP2 2.5693 9.4389 0.5523 23.8989
K5 GDSC1; GDSC2 2.8767 9.2426 -0.0172 21.4035
TT2609-C02 GDSC1; GDSC2; CTRP2 3.115 9.1255 1.2355 20.0175
HTC-C3 GDSC1; GDSC2 3.4904 6.8414 1.7005 9.7657
ASH-3 GDSC1; GDSC2 3.7247 7.4856 1.5655 9.963
SW579 CTRP2 3.9988 8.5451 2.3612 13.4568
8305C GDSC1; GDSC2; CTRP2 4.1297 12.7243 0.4179 20.5876
IHH-4 GDSC1; GDSC2 4.3123 8.1826 1.6593 7.937
CAL-62 GDSC1; GDSC2; CTRP2 4.547 6.5075 3.866 6.0049
CGTH-W-1 GDSC1; GDSC2; CTRP2 4.5597 6.7639 3.7535 6.4401
8505C GDSC1; GDSC2; CTRP2 4.6505 8.6003 2.9284 9.6815
WRO GDSC1; GDSC2 4.9276 10.6437 0.8974 10.9584
FTC-133 GDSC1; GDSC2; CTRP2 6.4597 11.5317 2.8912 6.644
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB771-HNC GDSC1; GDSC2 -4.4769 1.2138 -4.7202 70.1525
DOK GDSC1; GDSC2 -4.1883 14.4379 -9.2864 57.197
YD-10B CTRP2 -1.9908 5.0037 -2.6223 47.4126
NCI-H3118 GDSC1; GDSC2 -1.8706 8.4844 -4.272 51.0188
JHU-011 GDSC1; GDSC2 -1.4551 3.7559 -2.0161 48.3851
BB49-HNC GDSC1 -0.7834 12.3814 -6.0274 42.5668
BB30-HNC GDSC1; GDSC2 -0.1429 3.7729 -0.5915 36.6995
Ca9-22 GDSC1; GDSC2 0.0455 12.183 -4.0667 42.8085
KON GDSC1; GDSC2 0.2756 5.9046 -0.9428 35.7302
PCI-38 GDSC1 0.3152 5.8374 -1.8018 27.0393
KOSC-2 GDSC1; GDSC2 0.5601 5.8945 -0.6427 33.2656
JHU-029 GDSC1; GDSC2 0.882 8.8465 -1.667 35.1781
HO-1-N-1 GDSC1; GDSC2 0.9906 3.0904 0.837 24.1919
Detroit 562 GDSC1; GDSC2; CTRP2 1.0023 4.2545 0.821 27.5457
PE/CA-PJ49 CTRP2 1.0198 7.1903 -0.0757 30.4446
CAL-27 GDSC1; GDSC2; CTRP2 1.1739 2.5031 1.1719 25.7925
UPCI-SCC-090 GDSC1; GDSC2 1.3257 4.5645 0.7121 23.3609
BICR 10 GDSC1 1.5437 7.6842 -1.6529 21.2431
SCC-25 GDSC1; GDSC2; CTRP2 1.6438 5.1965 1.2906 23.8875
SNU-46 CTRP2 1.745 4.1783 1.6378 22.3467
CAL-33 GDSC1; GDSC2; CTRP2 1.7801 5.8964 1.2176 23.7373
BICR 18 CTRP2 2.1823 5.9432 1.6364 21.0212
YD-8 CTRP2 2.1976 5.6019 1.7692 20.487
HSC-3 GDSC1; GDSC2; CTRP2 2.2744 7.7445 1.0167 23.0463
HSC-2 GDSC1; GDSC2; CTRP2 2.3176 6.8564 1.4334 21.3887
PCI-06A GDSC1; GDSC2 2.5974 4.0356 2.2652 9.1459
PCI-30 GDSC1; GDSC2 2.7138 17.277 -4.1687 34.7163
SNU-1041 CTRP2 2.7166 9.5465 0.6474 23.1801
BICR 22 GDSC1; GDSC2; CTRP2 2.964 7.1357 1.9919 17.4942
PCI-15A GDSC1; GDSC2 2.9691 8.6133 0.3767 19.0939
PCI-04B GDSC1; GDSC2 3.0617 6.7607 1.3811 13.0126
BHY GDSC1; GDSC2; CTRP2 3.0896 8.9497 1.2935 19.8626
OSC-19 GDSC1; GDSC2 3.099 7.3626 1.1129 14.5191
SCC-15 GDSC1; GDSC2 3.1451 11.3437 -0.8372 24.2276
SCC-4 GDSC1; GDSC2; CTRP2 3.2227 13.0573 -0.5658 25.8241
JHU-022 GDSC1; GDSC2 3.2508 12.2377 -1.1953 25.307
BICR 31 GDSC1; GDSC2; CTRP2 3.3054 9.1016 1.4318 18.7978
SNU-899 CTRP2 3.4522 6.6496 2.7063 13.4061
BICR 6 CTRP2 3.4734 7.5291 2.334 14.8299
PE/CA-PJ34 (clone C12) CTRP2 3.6256 7.7634 2.3762 14.2828
OSC-20 GDSC1; GDSC2 3.6445 8.338 1.0774 13.127
SAS GDSC1; GDSC2 3.6815 6.5983 1.9729 7.5453
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 3.9114 9.8163 1.659 16.4769
SAT [Human HNSCC] GDSC1; GDSC2 3.993 8.9056 1.0677 12.2439
BICR 16 CTRP2 3.9962 7.1506 3.0274 10.7445
SNU-1076 CTRP2 4.0488 7.5742 2.8773 11.2304
SKN-3 GDSC1; GDSC2 4.5127 9.17 1.3211 9.4865
BICR 78 GDSC1; GDSC2 4.6481 7.532 2.1926 4.0869
FaDu GDSC1; GDSC2; CTRP2 4.7546 8.8873 2.8764 9.6829
HSC-4 GDSC1; GDSC2; CTRP2 5.2271 9.2277 3.103 7.8116
HO-1-u-1 GDSC1; GDSC2 5.3571 9.0045 1.944 4.274
SNU-1066 CTRP2 5.8952 10.5319 2.9734 7.1867
PE/CA-PJ41 (clone D2) CTRP2 6.3159 14.8792 1.1423 13.7104
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 6.6046 20.3397 -1.3346 21.1739
BICR 56 CTRP2 8.0543 16.9873 1.3568 10.2428
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-1 CTRP2 -2.0533 4.5863 -2.5814 47.7051
5637 GDSC1; GDSC2; CTRP2 -0.0508 6.3373 -0.9161 36.4115
BFTC-905 GDSC1; GDSC2; CTRP2 0.1115 8.3363 -1.4937 37.1452
RT-112 GDSC1; GDSC2; CTRP2 0.1412 4.9884 -0.2914 34.0277
JMSU-1 CTRP2 0.7761 2.5375 0.7684 28.4618
TCCSUP GDSC1; GDSC2; CTRP2 1.7525 6.4435 0.9919 24.6305
647V GDSC1; GDSC2; CTRP2 2.6404 4.8289 2.4764 16.5844
BC-3C CTRP2 2.7143 5.4714 2.3732 16.7363
U-BLC1 CTRP2 2.7604 5.8828 2.2813 16.9447
VM-CUB-1 CTRP2 3.3078 7.0151 2.3981 14.9992
J82 GDSC1; GDSC2; CTRP2 3.4724 7.0274 2.5605 13.9302
RT-4 GDSC1; GDSC2; CTRP2 3.5891 6.3915 2.9589 12.0509
639V GDSC1; GDSC2; CTRP2 3.8121 5.8515 3.4173 9.6638
SW780 GDSC1; GDSC2 3.9654 6.4492 2.2566 5.0868
SW1710 GDSC1; GDSC2; CTRP2 4.0148 5.6085 3.7287 7.9055
253J-BV CTRP2 4.1347 7.4752 3.0072 10.4964
KMBC-2 CTRP2 4.7087 12.5966 0.9851 17.3239
CAL-29 GDSC1; GDSC2; CTRP2 4.7345 6.7144 3.9389 5.2816
HT-1197 GDSC1; GDSC2; CTRP2 4.7802 9.4488 2.6183 10.7055
UM-UC-3 GDSC1; GDSC2; CTRP2 4.9009 9.7228 2.5846 10.6032
HT-1376 GDSC1; GDSC2; CTRP2 4.9222 9.7383 2.5948 10.5184
T24 GDSC1; GDSC2; CTRP2 5.0804 12.7874 1.2028 15.7598
KU-19-19 GDSC1; GDSC2; CTRP2 5.9847 10.8549 2.8807 7.4218
SCaBER CTRP2 6.8194 19.2553 -0.6415 18.7908
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-39 GDSC1; GDSC2 -2.5099 11.1978 -6.1258 53.2276
NT2-D1 GDSC1; GDSC2 -1.9703 4.2771 -2.7401 52.1856
SiSo GDSC1; GDSC2 -1.9079 3.5794 -2.4579 51.884
PA-1 GDSC1; GDSC2 -1.0037 0.5851 -1.0073 43.4201
TC-YIK GDSC2 -0.7441 2.0146 -0.8389 41.1733
BPH-1 GDSC1; GDSC2 -0.4852 4.6629 -1.2633 40.7897
SW954 GDSC1; GDSC2 0.1582 2.6193 0.0326 32.3675
ACC-OV7 GDSC2 0.4504 3.8414 0.0323 30.9001
SW962 GDSC1; GDSC2 0.7202 8.0333 -1.4427 35.223
KGN GDSC1; GDSC2 0.7727 6.944 -0.8891 33.1913
HeLa GDSC1; GDSC2; CTRP2 1.0256 3.3163 0.9823 26.9194
NCC-IT GDSC1; GDSC2 1.1502 6.7845 -0.4376 29.7691
PWR-1E GDSC2 1.2585 2.63 1.2143 20.9323
OVCA433 GDSC2 1.6131 13.2111 -3.1102 35.9159
OVMIU GDSC1; GDSC2 1.9515 4.8465 1.2471 17.733
C-4-I GDSC1; GDSC2 2.6113 6.0772 1.315 14.89
LB831-BLC GDSC1; GDSC2 3.0079 5.8607 1.7822 10.6935
JAR GDSC1; GDSC2 3.0927 4.9424 2.3135 7.0834
OV17R GDSC2 3.1536 5.9965 1.8419 9.8651
DSH1 GDSC1; GDSC2 3.1842 4.9068 2.412 6.1742
PEO1 GDSC2 3.2669 7.5964 1.1387 13.855
JHOS-3 GDSC2 3.3894 8.2797 0.899 14.9008
SKN GDSC1; GDSC2 3.5551 7.5974 1.3753 11.5908
MS751 GDSC1; GDSC2 3.6105 8.9746 0.7323 15.2103
HEY GDSC2 3.6393 6.4637 2.007 7.4428
NEC8 GDSC1; GDSC2 3.6871 13.1486 -1.2905 24.4017
SKG-IIIa GDSC1; GDSC2 3.7452 5.4837 2.5702 3.6605
UWB1.289 GDSC2 3.7896 8.2684 1.2268 11.8446
OVCA420 GDSC2 3.9059 8.1376 1.3818 10.607
ME-180 GDSC1; GDSC2 3.9475 8.1036 1.4304 10.2053
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 4.1309 7.5217 1.8521 7.1864
JEG-3 GDSC1; GDSC2 4.1361 8.6159 1.3191 10.3976
Ca Ski GDSC1; GDSC2 4.2128 9.305 1.0365 11.8629
HT-3 GDSC1; GDSC2 4.2837 12.1208 -0.3039 18.673
DoTc2 4510 GDSC1; GDSC2 4.5253 10.2129 0.8206 12.3168
SiHa GDSC1; GDSC2 4.827 7.6334 2.2538 3.4371
SW756 GDSC1; GDSC2 4.9073 10.2543 1.0715 10.034
HEC-1 GDSC1; GDSC2 5.0186 9.994 1.272 8.664
C-33 A GDSC1; GDSC2 5.1753 7.5934 2.4614 1.88
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Discovery of a 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitor (BMS-754807) of insulin-like growth factor receptor (IGF-1R) kinase in cli... J Med Chem. 2009 Dec 10;52(23):7360-3.
2 CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers. Cancer Res. 2014 Jul 15;74(14):3947-58. doi: 10.1158/0008-5472.CAN-13-2923. Epub 2014 Jul 1.