| Drug Name |
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| Synonyms |
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| #Ro5 Violations (Lipinski): 1 |
Molecular Weight (mw) |
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| Logarithm of the Partition Coefficient (xlogp) |
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| Rotatable Bond Count (rotbonds) |
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| Hydrogen Bond Donor Count (hbonddonor) |
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| Hydrogen Bond Acceptor Count (hbondacc) |
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| ADMET Property |
- Bioavailability
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The bioavailability of drug is 82%
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- Clearance
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The clearance of drug is 9.42 L/h
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- Elimination
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In a clinical pharmacology study, baricitinib was excreted predominately as the unchanged active substance in urine (69 %) and feces (15 %) and only 4 minor oxidative metabolites were identified (3 in urine; 1 in feces) constituting approximately 5 % and 1 % of the dose, respectively
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- Half-life
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The concentration or amount of drug in body reduced by one-half in 12.5 hours
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- Metabolism
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The drug is metabolized via the CYP3A4
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- Vd
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The volume of distribution (Vd) of drug is 76 L
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| Cross-matching ID |
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