| Drug Name |
GTPL-9088
|
| Synonyms |
Clobetasona; Clobetasona [INN-Spanish]; Clobetasone; Clobetasone (INN); Clobetasone [INN:BAN]; Clobetasonum; Clobetasonum [INN-Latin]; LT69WY1J6D; SCHEMBL3581; XXIFVOHLGBURIG-OZCCCYNHSA-N; ZINC5752185; (8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione; 21-Chlor-9-fluor-17-hydroxy-16beta-methyl-1,4-pregnadien-3,11,20-trion; 54063-32-0; AC1L2G2H; API0002061; D07717; DB13158; EINECS 258-953-5; GTPL9088; UNII-LT69WY1J6D
|
| ATC Code |
- D07AB01: GTPL-9088
- D07AB: Corticosteroids, moderately potent (group II)
- D07A: CORTICOSTEROIDS, PLAIN
- D07: CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
- D: DERMATOLOGICALS
- S01BA09: GTPL-9088
- S01BA: Corticosteroids, plain
- S01B: ANTIINFLAMMATORY AGENTS
- S01: OPHTHALMOLOGICALS
- S: SENSORY ORGANS
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| Structure |
|
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3D MOL
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2D MOL
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| #Ro5 Violations (Lipinski): 0 |
Molecular Weight (mw) |
408.9 |
|
| Logarithm of the Partition Coefficient (xlogp) |
2.6 |
| Rotatable Bond Count (rotbonds) |
2 |
| Hydrogen Bond Donor Count (hbonddonor) |
1 |
| Hydrogen Bond Acceptor Count (hbondacc) |
5 |
| ADMET Property |
- Metabolism
-
The drug is metabolized via skin
[]
|
| Chemical Identifiers |
- Formula
- C22H26ClFO4
- IUPAC Name
(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione - Canonical SMILES
-
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(=O)CC2(C1(C(=O)CCl)O)C)F)C
- InChI
-
XXIFVOHLGBURIG-OZCCCYNHSA-N
- InChIKey
-
1S/C22H26ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-16,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,19-,20-,21-,22-/m0/s1
|
| Cross-matching ID |
- PubChem CID
- 71387
- CAS Number
-
- UNII
-
- DrugBank ID
-
- INTEDE ID
- DR0345
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