Details of the Drug

General Information of Drug (ID: DMPW5SB)

Drug Name
BAY 86-9766
Synonyms
923032-37-5; RDEA119; BAY 869766; RDEA 119; UNII-JPX07AFM0N; RDEA-119; Refametinib (RDEA119, Bay 86-9766); JPX07AFM0N; (S)-N-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide; N-[3,4-difluoro-2-(2-fluoro-4-iodoanilino)-6-methoxyphenyl]-1-[(2S)-2,3-dihydroxypropyl]cyclopropane-1-sulfonamide; Refametinib [INN]; 923032-38-6; BAY-869766; BAY 8697661; 3e8n; Refametinib R enantiomer; Refametinib (RDEA119); SCHEMBL345333
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 572.3
Logarithm of the Partition Coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C19H20F3IN2O5S
IUPAC Name
N-[3,4-difluoro-2-(2-fluoro-4-iodoanilino)-6-methoxyphenyl]-1-[(2S)-2,3-dihydroxypropyl]cyclopropane-1-sulfonamide
Canonical SMILES
COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)C[C@@H](CO)O)NC3=C(C=C(C=C3)I)F)F)F
InChI
InChI=1S/C19H20F3IN2O5S/c1-30-15-7-13(21)16(22)18(24-14-3-2-10(23)6-12(14)20)17(15)25-31(28,29)19(4-5-19)8-11(27)9-26/h2-3,6-7,11,24-27H,4-5,8-9H2,1H3/t11-/m0/s1
InChIKey
RDSACQWTXKSHJT-NSHDSACASA-N
Cross-matching ID
PubChem CID
44182295
CAS Number
923032-37-5
UNII
JPX07AFM0N
DrugBank ID
DB06309
TTD ID
D03SKL
INTEDE ID
DR1879
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MAPK/ERK kinase kinase (MAP3K) TTROQ37 NOUNIPROTAC Modulator [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [3]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 2.5082 8.4353 0.059 22.2582
H-EMC-SS GDSC1; GDSC2 -0.1709 3.0474 -0.4186 36.1703
SJSA-1 GDSC1; GDSC2 0.359 10.9795 -3.189 40.4976
CHSA0011 GDSC1; GDSC2 0.7452 3.8727 0.3423 27.9424
U2OS GDSC1; GDSC2 1.0714 3.5305 0.8058 23.9844
G-292 clone A141B1 GDSC1; GDSC2 1.9582 5.7047 0.8648 19.9264
CHSA0108 GDSC1; GDSC2 2.5085 7.3527 0.5941 19.4458
CAL-72 GDSC1; GDSC2 2.6685 7.7878 0.5235 19.2883
MG-63 GDSC1; GDSC2 2.85 11.1413 -0.9877 25.7472
CHSA8926 GDSC1; GDSC2 3.3922 7.8801 1.1011 13.7078
SK-PN-DW GDSC1; GDSC2 3.7948 5.7124 2.4942 4.0151
NY GDSC1; GDSC2 3.916 6.5782 2.1585 5.8066
ES1 GDSC1; GDSC2 3.9364 5.9455 2.4802 3.7853
EW-24 GDSC1; GDSC2 4.2294 5.768 2.7467 1.6999
ES7 GDSC1; GDSC2 4.4133 7.1745 2.2115 4.4166
U-CH2 GDSC2 4.6774 13.8635 -0.8663 20.1199
TC-71 GDSC1; GDSC2 4.7644 11.6251 0.3025 14.509
EW-7 GDSC1; GDSC2 4.7767 9.1997 1.4892 7.9242
HuO-3N1 GDSC1; GDSC2 4.8161 7.5937 2.2654 3.3917
HuO9 GDSC1; GDSC2 4.8473 11.0206 0.6578 12.4478
EW-22 GDSC1; GDSC2 4.875 9.1492 1.5787 7.2018
EW-16 GDSC1; GDSC2 4.9069 13.6229 -0.5747 18.3205
CAL-78 GDSC1; GDSC2 5.0649 9.8195 1.3856 7.9251
ES8 GDSC1; GDSC2 5.2301 8.9846 1.8785 4.8396
NOS-1 [Human HNSCC] GDSC1; GDSC2 5.2571 14.1581 -0.5803 17.5179
EW-12 GDSC2 5.2667 7.0702 2.7155 0.7365
EW-11 GDSC1; GDSC2 5.3347 8.0582 2.3462 2.2375
CADO-ES1 GDSC1; GDSC2 5.3777 7.0653 2.7636 0.5129
HOS GDSC1; GDSC2 5.5267 14.5914 -0.5977 16.9819
EW-13 GDSC1; GDSC2 5.5984 7.6517 2.6342 0.7867
MHH-ES-1 GDSC1; GDSC2 5.7828 9.6491 1.8973 3.8823
EW-1 GDSC1; GDSC2 5.9861 8.2121 2.5838 0.7077
SK-ES-1 GDSC1; GDSC2 6.1516 12.3392 0.8965 8.5174
ES4 GDSC1; GDSC2 6.1764 14.6495 -0.1759 13.7247
EW-18 GDSC1; GDSC2 6.2559 14.3808 0.0049 12.7297
EW-3 GDSC1; GDSC2 6.3158 15.0531 -0.2753 13.8961
ES5 GDSC1; GDSC2 6.3234 12.0525 1.1318 7.0103
A-673 GDSC1; GDSC2 7.715 20.6028 -1.9885 17.9092
ES6 GDSC1; GDSC2 7.7565 18.9626 -1.1837 14.9632
SaOS-2 GDSC1; GDSC2 8.2122 19.7735 -1.2732 14.5224
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 4.6071 6.3571 2.6942 1.4518
SU-DHL-1 GDSC2 -5.9387 13.2598 -10.5391 61.7041
OCI-AML-3 GDSC1; GDSC2 -5.2433 4.1543 -6.2655 68.0886
NB4 GDSC1; GDSC2 -5.2381 2.7916 -5.8806 70.2223
SKM-1 GDSC1; GDSC2 -4.729 3.479 -5.5076 67.3048
OCI-AML-2 GDSC1; GDSC2 -4.4654 5.889 -5.9939 63.3315
KMOE-2 GDSC1; GDSC2 -3.6056 -0.639 -3.6215 68.2403
JURL-MK1 GDSC1; GDSC2 -3.2475 0.1621 -3.2919 64.4946
Ku812 GDSC1; GDSC2 -2.8461 1.9108 -3.0833 59.651
HL-60 GDSC1; GDSC2 -2.7656 6.7247 -4.4839 55.7469
NOMO-1 GDSC1; GDSC2 -2.3483 19.9317 -10.0787 51.6615
KY821 GDSC1; GDSC2 -1.715 13.6071 -6.4477 50.1872
LAMA-84 GDSC1; GDSC2 -1.392 1.6788 -1.4847 47.4537
EoL-1 GDSC1; GDSC2 -1.2682 3.8593 -1.8438 46.8976
PL-21 GDSC1; GDSC2 -1.2014 8.3826 -3.539 47.623
ML-2 GDSC1; GDSC2 -1.1957 11.8264 -5.1025 48.1478
OCI-AML-5 GDSC1; GDSC2 -0.8947 4.7512 -1.7363 44.2656
Kasumi-1 GDSC1; GDSC2 -0.8826 2.0844 -0.9976 42.593
H9 GDSC1; GDSC2 -0.7625 7.8088 -2.837 44.9327
MEG-01 GDSC1; GDSC2 -0.6756 3.4884 -1.0873 41.4946
NCI-H929 GDSC1; GDSC2 -0.6678 3.8091 -1.1743 41.6752
TALL-1 [Human adult T-ALL] GDSC2 -0.5882 8.3365 -2.893 44.1428
MV4-11 GDSC1; GDSC2 -0.3842 4.6517 -1.1504 39.9037
A4/Fukuda GDSC1; GDSC2 0.2168 4.8065 -0.5626 34.6625
BV-173 GDSC1; GDSC2 0.6835 6.5819 -0.8164 33.3373
MOLT-13 GDSC1; GDSC2 0.7446 11.9342 -3.2839 39.2115
EM-2 GDSC1; GDSC2 0.7671 9.7163 -2.1924 36.9863
MOLM-13 GDSC1; GDSC2 0.9409 3.5274 0.6645 25.3429
Karpas-620 GDSC1; GDSC2 1.1478 13.1281 -3.493 38.1639
NKM-1 GDSC1; GDSC2 1.205 9.4553 -1.6484 33.824
MY-M12 GDSC1; GDSC2 1.2292 8.8933 -1.3548 32.8299
KCL-22 GDSC1; GDSC2 1.2673 7.0301 -0.435 29.2632
IM-9 GDSC1; GDSC2 1.5005 4.9239 0.7475 22.4247
JSC-1 GDSC1; GDSC2 1.5625 12.0201 -2.5683 34.9072
MHH-CALL-2 GDSC1 1.5761 5.1559 0.2438 19.071
KOPN-8 GDSC1; GDSC2 1.6899 16.5145 -4.6793 38.3295
YT GDSC1; GDSC2 1.7945 6.4968 0.333 23.4768
AMO1 GDSC1; GDSC2 2.0548 9.4359 -0.8461 27.8803
DND-41 GDSC1; GDSC2 2.0841 9.4269 -0.8149 27.6515
OCI-M1 GDSC1; GDSC2 2.1031 5.8494 0.9397 18.9446
MHH-CALL-4 GDSC2 2.1876 11.9968 -1.9937 31.3007
P31/FUJ GDSC1; GDSC2 2.3044 11.0881 -1.4386 29.1707
Hs 445 GDSC1; GDSC2 2.4114 9.3317 -0.4718 25.0702
MOLP-8 GDSC1; GDSC2 2.4612 11.0553 -1.2835 28.1095
OCI-Ly7 GDSC1; GDSC2 2.5208 3.644 2.3425 9.0118
U266B1 GDSC1; GDSC2 2.5563 11.5132 -1.428 28.3033
Mono-Mac-6 GDSC1; GDSC2 2.5972 5.7536 1.4596 14.0593
SUP-B15 GDSC1; GDSC2 2.7841 8.6415 0.2016 20.6098
CML-T1 GDSC1; GDSC2 2.8211 8.3446 0.382 19.5455
RPMI-8226 GDSC1; GDSC2 2.9056 9.723 -0.2318 22.3383
MOLM-16 GDSC1; GDSC2 2.9094 12.8527 -1.7914 28.4021
A3/Kawakami GDSC1; GDSC2 2.9161 9.6308 -0.1768 22.0458
OPM-2 GDSC1; GDSC2 3.1024 5.4832 2.0533 8.6925
WSU-NHL GDSC1 3.1278 4.7103 1.7137 2.5447
MM1.S GDSC1; GDSC2 3.262 17.9924 -4.0633 33.1042
P12-Ichikawa GDSC1 3.3267 7.3384 0.5937 10.2291
HT GDSC1; GDSC2 3.354 4.216 2.9013 2.5711
BONNA-12 GDSC2 3.4119 9.4187 0.3482 17.883
MC116 GDSC1; GDSC2 3.442 4.7665 2.6971 3.6209
SUP-B8 GDSC1; GDSC2 3.4449 5.2362 2.4653 5.0766
CTB-1 GDSC1; GDSC2 3.4613 5.4964 2.3486 5.7691
RL GDSC1; GDSC2 3.5088 4.8093 2.7277 3.2528
VL51 GDSC1; GDSC2 3.5285 10.6198 -0.1563 20.0722
RPMI-8402 GDSC1; GDSC2 3.5646 4.9404 2.705 3.255
ME1 GDSC1; GDSC2 3.5887 30.1278 -9.8593 39.4453
SR GDSC1; GDSC2 3.5959 7.2493 1.5817 10.212
SIG-M5 GDSC2 3.5992 5.1893 2.608 3.7751
SUP-T1 GDSC1; GDSC2 3.6094 5.3461 2.5383 4.1861
SCC-3 GDSC2 3.6238 7.325 1.5661 10.2321
JVM-3 GDSC1; GDSC2 3.6633 14.2459 -1.8583 26.4423
KE-37 GDSC1; GDSC2 3.6735 5.5946 2.4637 4.4934
WSU-DLCL2 GDSC1; GDSC2 3.6804 5.0453 2.7376 2.7785
KG-1 GDSC1; GDSC2 3.6841 12.186 -0.812 22.5371
Farage GDSC1; GDSC2 3.7334 14.8912 -2.1235 27.0898
Namalwa GDSC1; GDSC2 3.7462 6.8796 1.8831 7.9384
NALM-6 GDSC1; GDSC2 3.778 9.6883 0.5104 15.9639
GDM-1 GDSC1; GDSC2 3.7992 6.1878 2.2646 5.4272
BC-1 GDSC1; GDSC2 3.8119 7.2982 1.7259 8.7453
KMS-12-BM GDSC2 3.87 6.4014 2.2116 5.5867
ST486 GDSC1 3.883 6.5713 1.314 3.7592
WIL2 NS GDSC1; GDSC2 3.8964 5.8953 2.4769 3.893
HAL-01 GDSC1; GDSC2 3.9017 13.6563 -1.3704 24.1046
TUR GDSC1; GDSC2 3.9054 6.166 2.352 4.6378
U-698-M GDSC1; GDSC2 3.9254 6.5053 2.2009 5.5226
Karpas-299 GDSC1; GDSC2 3.9532 9.6204 0.6821 14.5444
NK-92MI GDSC2 3.968 6.5142 2.227 5.2635
SU-DHL-16 GDSC1; GDSC2 4.0097 5.4044 2.7827 1.8566
L-540 GDSC1; GDSC2 4.0576 6.4853 2.3034 4.5971
DB GDSC1; GDSC2 4.0695 6.4731 2.3174 4.4864
SU-DHL-10 GDSC1; GDSC2 4.0793 5.445 2.8054 1.6156
GR-ST GDSC1; GDSC2 4.0798 6.0715 2.5158 3.2751
CCRF-CEM GDSC1; GDSC2 4.1305 6.2256 2.476 3.4107
RPMI-8866 GDSC1; GDSC2 4.1439 7.2112 2.0124 6.1785
Loucy GDSC1; GDSC2 4.1467 7.0032 2.115 5.5472
Reh GDSC1; GDSC2 4.1493 6.1312 2.5324 3.0432
OCI-Ly19 GDSC1; GDSC2 4.1633 16.3607 -2.5103 27.1184
Jurkat GDSC1; GDSC2 4.1714 6.0817 2.5694 2.7874
RC-K8 GDSC1 4.1981 5.7596 1.8044 0.6122
EHEB GDSC1 4.2176 11.5424 -0.8199 16.6098
LC4-1 GDSC1; GDSC2 4.2253 7.8664 1.7514 7.581
VAL GDSC1; GDSC2 4.269 6.4358 2.4657 3.207
HC-1 GDSC1; GDSC2 4.2861 15.1878 -1.8279 24.6904
MOLT-4 GDSC1; GDSC2 4.289 7.5604 1.9444 6.2691
697 GDSC1; GDSC2 4.3035 10.7328 0.3994 15.1507
SK-MM-2 GDSC1; GDSC2 4.31 6.8346 2.3049 4.0684
Karpas-422 GDSC1; GDSC2 4.3289 8.3099 1.6092 8.2008
BALL-1 GDSC1; GDSC2 4.3852 6.5027 2.506 2.7709
DG-75 GDSC1; GDSC2 4.4317 6.5266 2.5227 2.5998
SUP-M2 GDSC1; GDSC2 4.4397 10.5081 0.6125 13.6693
HH [Human lymphoma] GDSC1; GDSC2 4.451 7.4044 2.1275 4.8372
RS4;11 GDSC1; GDSC2 4.4718 6.9412 2.3572 3.4627
MN-60 GDSC1; GDSC2 4.4765 8.8187 1.4662 8.716
SU-DHL-5 GDSC1; GDSC2 4.5016 14.7572 -1.4448 22.805
PF-382 GDSC1; GDSC2 4.5107 11.5818 0.136 15.9743
ARH-77 GDSC1; GDSC2 4.5404 9.4085 1.2246 9.985
KM-H2 GDSC1; GDSC2 4.6069 6.9831 2.4189 2.8869
CMK GDSC1 4.6116 9.7176 0.3134 8.8703
P32/ISH GDSC1; GDSC2 4.6127 6.3531 2.6988 1.4227
KMS-11 GDSC1; GDSC2 4.6173 10.1757 0.9054 11.6259
THP-1 GDSC1; GDSC2 4.6236 12.6614 -0.3124 17.8424
BL-41 GDSC1; GDSC2 4.6363 5.996 2.8571 0.7013
K-562 GDSC1; GDSC2 4.6625 15.4664 -1.6725 23.2152
BE-13 GDSC1; GDSC2 4.6901 9.7738 1.1529 10.0565
Sc-1 GDSC1 4.6975 6.0741 1.8806 0.1747
LP-1 GDSC1; GDSC2 4.7219 6.9533 2.4975 2.2899
DEL GDSC1; GDSC2 4.7627 11.5505 0.3379 14.3315
DoHH2 GDSC1; GDSC2 4.7644 6.0993 2.8732 0.5426
JeKo-1 GDSC1; GDSC2 4.7976 9.788 1.2207 9.4289
Jiyoye GDSC1; GDSC2 4.819 6.722 2.6479 1.4204
CTV-1 GDSC1; GDSC2 4.8535 9.9193 1.1959 9.448
L-428 GDSC1; GDSC2 4.8706 6.3167 2.8352 0.5999
Ramos.2G6.4C10 GDSC1; GDSC2 4.9047 10.8777 0.768 11.7199
Raji GDSC1; GDSC2 4.9136 6.4477 2.8031 0.6826
TK [Human B-cell lymphoma] GDSC1; GDSC2 4.9816 6.9093 2.6501 1.2365
JVM-2 GDSC1; GDSC2 5.0077 12.7653 -0.0792 15.8171
SU-DHL-8 GDSC1; GDSC2 5.0315 6.5002 2.8332 0.5005
MLMA GDSC1; GDSC2 5.0583 8.2281 2.1203 3.7952
Karpas-231 GDSC1; GDSC2 5.065 6.3004 2.9197 0.2487
L-1236 GDSC1; GDSC2 5.0722 8.4834 2.0128 4.3628
EB2 GDSC1; GDSC2 5.0807 6.7599 2.7549 0.7317
ATN-1 GDSC1; GDSC2 5.0915 7.8119 2.3237 2.6666
RPMI-6666 GDSC1; GDSC2 5.1141 13.584 -0.403 17.0672
ALL-PO GDSC1; GDSC2 5.1467 12.2177 0.2878 13.6924
CRO-AP2 GDSC1; GDSC2 5.1553 11.4612 0.6604 11.7402
SU-DHL-4 GDSC1; GDSC2 5.1763 6.5235 2.8822 0.2919
CA46 GDSC1; GDSC2 5.1853 7.1443 2.6504 1.0434
EJM GDSC1; GDSC2 5.2507 8.9524 1.9054 4.657
HDLM-2 GDSC1; GDSC2 5.2985 8.0426 2.3341 2.3407
Daudi GDSC1; GDSC2 5.3564 6.7573 2.867 0.2579
ALL-SIL GDSC1; GDSC2 5.3987 13.9497 -0.3764 16.2931
RCH-ACV GDSC1; GDSC2 5.4107 8.577 2.1632 3.0454
GA-10 GDSC1; GDSC2 5.4753 12.5285 0.3662 12.5721
NU-DUL-1 GDSC1; GDSC2 5.4804 12.7341 0.2706 13.0412
L-363 GDSC1; GDSC2 5.4822 10.9175 1.1382 8.4784
HEL GDSC1; GDSC2 5.5008 6.6862 2.9433 0.0945
SUP-HD1 GDSC1; GDSC2 5.5046 13.4656 -0.0662 14.6255
MOLT-16 GDSC1; GDSC2 5.5244 11.5147 0.8836 9.7729
P30/OHK GDSC1; GDSC2 5.5936 7.4562 2.7058 0.5642
Granta-519 GDSC1; GDSC2 5.6109 7.2218 2.7978 0.3173
Karpas-45 GDSC1; GDSC2 5.7788 14.1822 -0.2221 14.7588
QIMR-WIL GDSC1; GDSC2 5.8064 15.2124 -0.7016 16.8119
BC-3 GDSC2 5.9072 7.4069 2.8412 0.1534
MHH-PREB-1 GDSC1; GDSC2 5.9406 7.4096 2.8519 0.1322
ROS-50 GDSC1; GDSC2 6.2083 7.9518 2.7615 0.2069
CESS GDSC1; GDSC2 6.4255 16.3896 -0.8413 16.1039
SU-DHL-6 GDSC1; GDSC2 6.7439 18.1056 -1.449 17.8306
Karpas-1106P GDSC1; GDSC2 6.9887 17.5799 -1.0314 15.7692
JJN-3 GDSC1; GDSC2 7.3672 22.7101 -3.2428 22.3324
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-GT-4 GDSC1; GDSC2 -0.6295 6.6486 -2.2002 43.447
ESO-51 GDSC1; GDSC2 -0.2779 3.0832 -0.5441 37.2809
OACP4 C GDSC1; GDSC2 0.1795 5.2654 -0.7813 35.6644
TE-12 GDSC1; GDSC2 2.3406 9.3023 -0.5209 25.529
KYSE-220 GDSC1; GDSC2 2.5372 10.794 -1.0866 27.1386
KYSE-50 GDSC1; GDSC2 4.1391 7.7756 1.7339 7.8886
OACM5.1 C GDSC1; GDSC2 4.6635 6.6235 2.6096 1.7965
FLO-1 GDSC1; GDSC2 4.7036 15.9894 -1.9004 23.8901
KYAE-1 GDSC1; GDSC2 5.0884 10.5227 1.0661 9.6747
ESO-26 GDSC1; GDSC2 5.1117 8.3364 2.1025 3.8067
HCE-4 GDSC1; GDSC2 5.4392 12.9419 0.1417 13.7675
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 3.9995 6.7297 2.1444 5.6987
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 GDSC1; GDSC2 -6.3669 0.1592 -6.5861 79.0427
SK-N-AS GDSC1; GDSC2 -1.7533 3.6098 -2.2981 50.7168
NB69 GDSC1; GDSC2 -1.6566 2.7544 -1.9675 49.9659
LA-N-6 GDSC1; GDSC2 -0.2664 6.8827 -1.923 41.0645
SJNB-5 GDSC1; GDSC2 0.1796 4.3539 -0.4358 34.3517
NH-12 GDSC1; GDSC2 0.5194 5.1771 -0.3864 32.4375
GI-ME-N GDSC1; GDSC2 0.6533 10.4086 -2.6333 38.3806
MHH-NB-11 GDSC1; GDSC2 0.7802 11.6468 -3.1108 38.7876
SK-N-BE(2)-M17 GDSC1; GDSC2 1.3632 5.9786 0.1435 26.1907
SK-N-FI GDSC1; GDSC2 1.6005 9.7601 -1.4243 31.6173
SiMa GDSC1; GDSC2 1.7887 7.7903 -0.2906 26.5352
NB(TU)1 GDSC1; GDSC2 1.9529 4.4091 1.4362 16.6229
SK-N-SH GDSC1; GDSC2 2.3732 6.9302 0.6769 19.4584
NB1 GDSC1; GDSC2 2.5994 5.8178 1.4304 14.2299
SJNB-14 GDSC1; GDSC2 3.6089 10.2929 0.0726 18.7218
SK-N-DZ GDSC1; GDSC2 3.6591 6.6949 1.9075 8.0138
Kelly GDSC1; GDSC2 4.0602 18.4518 -3.6369 30.2435
SJNB-17 GDSC1; GDSC2 4.0843 6.2999 2.4104 3.8948
IMR-5 GDSC1; GDSC2 4.3281 6.6508 2.4026 3.4627
SJNB-10 GDSC1; GDSC2 4.3481 14.445 -1.4093 23.0661
KP-N-YN GDSC1; GDSC2 4.3761 8.1539 1.7181 7.4403
GOTO GDSC1; GDSC2 4.3886 6.3015 2.5992 2.2497
CHP-134 GDSC1 4.5668 5.9883 1.8635 0.2478
SJNB-13 GDSC1; GDSC2 4.6521 7.0571 2.4118 2.8533
SJNB-12 GDSC1; GDSC2 4.7666 10.3456 0.9291 11.1471
CHP-126 GDSC1; GDSC2 4.8801 6.9055 2.6016 1.5661
SJNB-6 GDSC1; GDSC2 4.8867 7.0718 2.5345 1.8803
SK-N-MC-IXC GDSC1; GDSC2 4.9874 6.0481 2.9797 0.1514
KP-N-YS GDSC1; GDSC2 5.7366 14.4387 -0.3754 15.5441
KP-N-RT-BM-1 GDSC2 5.928 8.1817 2.5713 0.7807
TGW GDSC1; GDSC2 6.6797 17.0285 -0.9753 16.1411
SJNB-7 GDSC1; GDSC2 7.0895 16.4694 -0.4398 13.1489
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 -0.2467 9.4219 -3.0452 42.774
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1; GDSC2 -4.7088 -2.8996 -4.7089 79.8363
MDA-MB-231 GDSC1; GDSC2 0.4021 5.1144 -0.4854 33.4203
HCC1143 GDSC1; GDSC2 1.0609 7.3684 -0.7964 31.5873
Hs 578T GDSC1; GDSC2 1.5918 11.7816 -2.4241 34.4626
HDQ-P1 GDSC1; GDSC2 2.0894 9.7021 -0.9457 28.1414
MDA-MB-175-VII GDSC1; GDSC2 2.5882 6.6432 1.0162 16.7581
MFM-223 GDSC1; GDSC2 2.6322 4.5872 2.0512 10.3041
UACC-893 GDSC1; GDSC2 2.6654 7.5308 0.6481 18.6101
HCC1569 GDSC1; GDSC2 2.8577 6.5879 1.2876 14.2337
CAL-85-1 GDSC1; GDSC2 2.9018 10.8155 -0.7805 24.7548
JIMT-1 GDSC1; GDSC2 3.5176 8.9037 0.6924 15.7019
COLO 824 GDSC1; GDSC2 3.6525 9.7507 0.3787 17.0223
MDA-MB-453 GDSC1; GDSC2 3.6538 5.8634 2.3161 5.4659
MDA-MB-468 GDSC1; GDSC2 3.7658 8.3185 1.1833 12.1679
MRK-nu-1 GDSC1; GDSC2 3.8362 5.301 2.7212 2.5425
CAMA-1 GDSC1; GDSC2 3.8728 6.0147 2.4024 4.402
MDA-MB-436 GDSC1; GDSC2 3.8814 14.808 -1.9618 26.186
HCC70 GDSC1; GDSC2 3.8927 14.5444 -1.8211 25.6976
Evsa-T GDSC1; GDSC2 4.0656 7.058 2.0315 6.2396
HCC1954 GDSC1; GDSC2 4.0938 9.6795 0.7613 13.7316
HCC1395 GDSC1; GDSC2 4.1035 9.7292 0.744 13.8028
CAL-120 GDSC1; GDSC2 4.1482 11.2313 0.033 17.4242
HCC1419 GDSC1; GDSC2 4.1752 6.3571 2.4429 3.5184
HCC1428 GDSC1; GDSC2 4.1969 6.1561 2.5507 2.8483
EFM-192A GDSC1; GDSC2 4.2474 7.2257 2.0771 5.5584
BT-483 GDSC1; GDSC2 4.2788 6.3542 2.5096 2.9364
MCF-7 GDSC1; GDSC2 4.3512 7.2107 2.1539 4.8809
UACC-812 GDSC2 4.3872 7.5371 2.0223 5.5914
BT-20 GDSC1; GDSC2 4.5183 13.3299 -0.7233 19.9234
EFM-19 GDSC1; GDSC2 4.6256 7.046 2.4014 2.9527
HCC1187 GDSC1; GDSC2 4.7151 12.7466 -0.2857 17.4922
MDA-MB-415 GDSC1; GDSC2 4.7423 11.955 0.1243 15.4607
MDA-MB-157 GDSC1; GDSC2 4.8366 11.1007 0.6112 12.7223
ZR-75-30 GDSC1; GDSC2 4.8411 7.7003 2.2317 3.536
YMB-1-E GDSC2 4.8916 7.4517 2.3719 2.7014
CAL-148 GDSC2 4.9637 6.4917 2.8078 0.6291
HCC202 GDSC1 5.059 7.197 1.6187 0.7088
BT-474 GDSC1; GDSC2 5.2649 11.3677 0.7805 10.8616
AU565 GDSC1; GDSC2 5.307 8.0912 2.3178 2.4099
T-47D GDSC1; GDSC2 5.3786 11.5862 0.7526 10.7705
HCC2157 GDSC1; GDSC2 5.4194 7.2267 2.7203 0.6206
HCC2218 GDSC1; GDSC2 5.4433 11.1283 1.0135 9.2346
OCUB-M GDSC1; GDSC2 5.5624 7.2112 2.7831 0.371
HCC38 GDSC1; GDSC2 5.5793 8.4799 2.2926 2.2013
CAL-51 GDSC1; GDSC2 5.7136 14.089 -0.2222 14.8992
HCC1599 GDSC2 5.859 7.505 2.7901 0.25
MDA-MB-361 GDSC1; GDSC2 5.9498 17.1768 -1.5563 19.8477
BT-549 GDSC1; GDSC2 6.0901 14.6123 -0.2162 14.0834
HCC1806 GDSC1; GDSC2 6.5727 23.6944 -4.2984 26.4115
HCC1937 GDSC1; GDSC2 6.6768 16.8359 -0.885 15.7845
HCC1500 GDSC1; GDSC2 6.7233 15.2628 -0.1077 12.356
MDA-MB-330 GDSC1; GDSC2 6.8074 8.7967 2.6848 0.1913
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ONS-76 GDSC1; GDSC2 -1.2338 2.2062 -1.3957 46.0617
D-245MG GDSC2 0.2243 4.3599 -0.3897 33.9307
D-263MG GDSC1; GDSC2 0.3634 10.0197 -2.7269 39.7133
DK-MG GDSC1; GDSC2 0.6557 5.7916 -0.4995 32.2502
YKG-1 GDSC1; GDSC2 1.241 5.1245 0.3925 25.442
MOG-G-UVW GDSC1; GDSC2 1.4987 4.2121 1.034 20.8288
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 1.6437 9.9653 -1.4845 31.6503
YH-13 GDSC1; GDSC2 1.7019 4.2542 1.2341 18.8303
A-172 GDSC1; GDSC2 1.7813 7.468 -0.1424 25.8834
KALS-1 GDSC1; GDSC2 1.8251 7.8633 -0.2913 26.3986
SF539 GDSC1; GDSC2 1.8901 7.3676 0.0097 24.739
D-247MG GDSC1; GDSC2 1.9718 8.4268 -0.4276 26.4508
H4 GDSC1; GDSC2 2.0104 8.8554 -0.6016 27.0517
GB-1 GDSC1; GDSC2 2.1564 4.6358 1.5497 15.1399
CAS-1 GDSC1; GDSC2 2.3815 6.8841 0.7071 19.2592
D-566MG GDSC1; GDSC2 2.4148 5.7512 1.2879 15.7445
AM-38 GDSC1; GDSC2 2.6327 4.8589 1.9239 11.0819
D-336MG GDSC1; GDSC2 2.7215 9.564 -0.3126 23.3114
NMC-G1 GDSC1; GDSC2 2.7722 10.3427 -0.6565 24.6555
Becker GDSC1; GDSC2 2.8387 13.6881 -2.2692 30.0528
D-423MG GDSC1; GDSC2 2.8528 9.5611 -0.1967 22.3444
U-87MG ATCC GDSC1 2.9191 8.8414 -0.4545 18.4673
SF126 GDSC1; GDSC2 2.9972 8.533 0.4411 18.6618
KINGS-1 GDSC1; GDSC2 3.2866 12.9988 -1.546 26.4639
U-118MG GDSC1; GDSC2 3.442 8.6108 0.7769 15.4459
MOG-G-CCM GDSC1; GDSC2 3.5316 11.1902 -0.4389 21.3697
SW1088 GDSC1; GDSC2 3.6368 10.7199 -0.118 19.5749
LN-229 GDSC1; GDSC2 3.6648 15.6911 -2.5793 28.6022
PFSK-1 GDSC1 3.7173 6.2431 1.3659 3.7335
GaMG GDSC1; GDSC2 3.9036 12.4577 -0.7708 21.7516
Daoy GDSC1; GDSC2 3.9288 9.4036 0.7709 14.115
DBTRG-05MG GDSC1; GDSC2 3.9303 16.2495 -2.6421 28.0828
SF268 GDSC1; GDSC2 4.0115 9.6113 0.7318 14.1129
Hs 683 GDSC1; GDSC2 4.0361 12.5245 -0.6986 21.0848
KNS-81-FD GDSC1; GDSC2 4.074 12.5899 -0.7011 20.993
SK-MG-1 GDSC1; GDSC2 4.2778 11.3492 0.0744 16.8777
42-MG-BA GDSC1; GDSC2 4.453 10.6426 0.5561 13.9404
U-251MG GDSC1; GDSC2 4.4578 12.0242 -0.1226 17.3726
SW1783 GDSC1; GDSC2 4.4725 9.9279 0.9219 11.8781
D-392MG GDSC1; GDSC2 4.6453 16.2972 -2.0985 24.6767
M059J GDSC1; GDSC2 4.7152 14.1679 -0.9882 20.5218
D-502MG GDSC1; GDSC2 4.7527 17.0337 -2.3811 25.2933
GI-1 GDSC1; GDSC2 4.763 11.2632 0.4788 13.5974
Onda 11 GDSC1; GDSC2 4.8258 11.9698 0.1783 14.99
SNB-75 GDSC1; GDSC2 4.8628 16.1724 -1.8687 23.3998
SF295 GDSC1; GDSC2 4.9473 10.8423 0.815 11.368
D283 Med GDSC1; GDSC2 4.9483 10.7768 0.8475 11.188
LNZTA3WT4 GDSC1; GDSC2 5.0367 13.9036 -0.6167 18.1921
LN-405 GDSC1; GDSC2 5.138 11.3377 0.708 11.524
D-542MG GDSC1; GDSC2 5.1696 16.7531 -1.9229 22.8591
T98G GDSC1; GDSC2 5.2768 9.144 1.8337 5.0078
LN-18 GDSC1; GDSC2 5.7713 14.2469 -0.2585 14.9415
Onda 10 GDSC1; GDSC2 6.5338 16.7107 -0.9218 16.2144
KNS-42 GDSC1; GDSC2 6.8741 15.0422 0.0913 11.1694
8-MG-BA GDSC1; GDSC2 7.4283 19.8626 -1.8271 17.8792
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 3.3696 8.1648 0.9401 14.7209
TGBC1TKB GDSC1; GDSC2 3.7909 10.2213 0.2548 17.2787
ETK-1 GDSC1; GDSC2 4.5764 11.3789 0.2851 15.056
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1; GDSC2 -0.6938 4.4945 -1.4287 42.4371
MFE-296 GDSC1; GDSC2 2.2299 9.7403 -0.8373 27.2233
ESS-1 GDSC1; GDSC2 2.855 5.7737 1.6881 11.777
AN3-CA GDSC1; GDSC2 3.7382 8.741 0.951 13.6063
KLE GDSC1; GDSC2 3.9897 8.3777 1.3267 10.7221
MFE-280 GDSC1; GDSC2 4.9946 9.5472 1.4685 7.5941
MFE-319 GDSC1; GDSC2 5.2729 13.0186 -0.0124 14.8852
EN GDSC1; GDSC2 8.7425 19.7152 -0.9188 12.3327
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC1; GDSC2 0.5006 7.3523 -1.3483 35.9288
LB1047-RCC GDSC1; GDSC2 0.6911 5.3371 -0.2712 31.1228
RXF 393L GDSC1; GDSC2 0.9398 5.6808 -0.1577 29.4693
SW13 GDSC1; GDSC2 1.5035 10.1483 -1.7042 32.8471
786-O GDSC1; GDSC2 1.527 6.4207 0.1053 25.7022
TK-10 GDSC1; GDSC2 1.7065 8.7891 -0.8521 29.193
LB2241-RCC GDSC1; GDSC2 1.8631 6.913 0.2019 23.8861
BB65-RCC GDSC1; GDSC2 1.9745 10.0762 -1.2348 29.6104
A-704 GDSC1; GDSC2 2.0946 5.3757 1.1526 17.7333
KTCTL-1M GDSC1; GDSC2 2.113 7.5678 0.1231 23.3435
CAL-54 GDSC1; GDSC2 2.5362 15.0488 -3.2085 33.2937
VMRC-RCW GDSC1; GDSC2 2.8026 7.3545 0.858 16.9623
KTCTL-195 GDSC1; GDSC2 2.874 8.3327 0.4342 19.0941
769-P GDSC1; GDSC2 3.1232 10.8723 -0.6201 23.3901
UO-31 GDSC1; GDSC2 3.2596 6.4716 1.6948 10.4678
NCC021 GDSC1; GDSC2 3.2962 6.7367 1.5931 10.9935
KTCTL-13 GDSC1; GDSC2 3.3469 6.6135 1.6969 10.1982
KMRC-1 GDSC1; GDSC2 3.6901 12.1701 -0.7992 22.4675
A-498 GDSC1; GDSC2 3.7209 12.8 -1.0889 23.5429
Caki-1 GDSC1; GDSC2 3.8047 14.8822 -2.061 26.7048
KTCTL-26A GDSC1; GDSC2 4.1889 10.164 0.5938 14.407
LB996-RCC GDSC1; GDSC2 4.2821 10.1892 0.652 13.8504
SW156 GDSC1; GDSC2 4.4845 13.0653 -0.618 19.5585
BFTC-909 GDSC1; GDSC2 4.5926 9.1391 1.3922 8.8904
RCC10RGB GDSC1; GDSC2 4.5942 19.9891 -3.9765 29.7564
KMRC-20 GDSC1; GDSC2 4.6956 13.5694 -0.7069 19.4078
SN12C GDSC1; GDSC2 5.1339 17.5156 -2.3272 24.2381
HA7-RCC GDSC1; GDSC2 5.1813 12.479 0.1852 14.1277
ACHN GDSC1; GDSC2 5.2987 18.5557 -2.7168 25.0217
NCC010 GDSC1; GDSC2 5.3049 14.8734 -0.8961 18.7395
KTCTL-21 GDSC1; GDSC2 5.4048 17.5204 -2.125 22.9864
OS-RC-2 GDSC1; GDSC2 5.5377 15.785 -1.1733 19.3158
VMRC-RCZ GDSC1; GDSC2 5.7168 17.6355 -1.9503 21.7221
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO205 GDSC1; GDSC2 -3.6184 2.5345 -4.0526 63.6951
HT-29 GDSC1; GDSC2 -2.6677 3.3483 -3.2219 57.248
CL-11 GDSC1; GDSC2 -2.4687 3.1424 -2.9494 56.069
MDST8 GDSC1; GDSC2 -2.2688 4.2257 -3.0482 54.1873
HCC2998 GDSC1; GDSC2 -2.0977 3.4132 -2.6178 53.3245
LS513 GDSC1; GDSC2 -1.9906 1.6803 -2.1241 52.9901
SK-CO-1 GDSC1; GDSC2 -1.7748 1.9511 -1.9349 51.0305
SW620 GDSC1; GDSC2 -1.1394 6.6552 -2.7366 46.8355
LS411N GDSC1; GDSC2 -0.9775 9.6767 -3.892 46.7629
RCM-1 [Human ESC] GDSC1; GDSC2 -0.9678 4.9939 -1.903 44.9724
NCI-H747 GDSC1; GDSC2 -0.9147 5.7032 -2.1157 44.9319
SW626 GDSC1; GDSC2 -0.563 5.6379 -1.7165 42.2531
SNU-C1 GDSC1; GDSC2 -0.5518 13.4888 -5.2649 45.8782
LoVo GDSC1; GDSC2 -0.4741 4.888 -1.3335 40.9025
HCT 116 GDSC1; GDSC2 -0.4523 3.8707 -0.959 39.7494
NCI-H508 GDSC1; GDSC2 -0.4338 8.385 -2.7584 43.2458
SNU-407 GDSC1; GDSC2 -0.4248 9.7346 -3.3668 43.9252
DiFi GDSC1; GDSC2 0.0155 4.1639 -0.547 35.6634
SW1116 GDSC1; GDSC2 0.4156 7.6697 -1.5783 36.9661
SW1463 GDSC1; GDSC2 0.5529 4.8445 -0.2188 31.5533
LS1034 GDSC1; GDSC2 0.5618 7.0337 -1.1425 35.0137
NCI-H716 GDSC1; GDSC2 0.8256 7.5722 -1.1242 33.7682
RKO GDSC1; GDSC2 0.9801 5.8103 -0.1725 29.3556
HT-55 GDSC1; GDSC2 1.1687 6.5912 -0.3305 29.2317
C2BBe1 GDSC1; GDSC2 1.2986 5.3192 0.3691 25.3164
SNU-C5 GDSC1; GDSC2 1.3042 9.3942 -1.5248 33.0664
HT115 GDSC1; GDSC2 1.5292 5.7941 0.3945 24.2172
SW1417 GDSC1; GDSC2 1.5429 11.8121 -2.4837 34.7756
KM12 GDSC1; GDSC2 1.7698 6.6359 0.2432 24.0376
SNU-81 GDSC1; GDSC2 1.9131 9.9027 -1.2055 29.7282
SNU-175 GDSC2 1.9688 8.9257 -0.6745 27.5055
SW837 GDSC1; GDSC2 2.1198 12.393 -2.2507 32.2415
LS180 GDSC1; GDSC2 2.2078 10.6466 -1.3058 29.0424
SW948 GDSC1; GDSC2 2.2646 9.7214 -0.7967 26.9407
LS123 GDSC1; GDSC2 2.2959 10.5007 -1.1547 28.2015
HCT 15 GDSC1; GDSC2 2.3672 8.8918 -0.2938 24.4286
COLO 678 GDSC1; GDSC2 2.7135 19.6432 -5.3511 36.606
GP5d GDSC1; GDSC2 2.7596 15.4 -3.1919 32.619
SNU-61 GDSC1; GDSC2 3.2566 9.5658 0.1454 19.3999
CW-2 GDSC1; GDSC2 3.4768 13.1243 -1.4508 25.5804
T84 GDSC1; GDSC2 3.5015 7.608 1.3266 12.0385
SNU-1040 GDSC1 3.7816 9.894 -0.3274 15.0228
SW48 GDSC1; GDSC2 3.8305 17.006 -3.1011 29.541
SNU-C2B GDSC1; GDSC2 4.0719 20.4171 -4.6089 32.2082
CaR-1 GDSC1; GDSC2 4.0836 15.9899 -2.389 26.9684
CCK-81 GDSC1; GDSC2 4.2433 17.3304 -2.93 28.0744
SNU-283 GDSC2 4.8929 11.9885 0.2179 14.6319
COLO 320HSR GDSC1; GDSC2 5.0786 6.935 2.6851 0.9989
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 4.4177 9.1127 1.2812 9.9411
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC1; GDSC2 -1.4747 3.7308 -2.0299 48.5411
Hep 3B2.1-7 GDSC1; GDSC2 0.3487 1.4477 0.3461 29.8499
SK-HEP-1 GDSC1; GDSC2 0.8576 6.2364 -0.4854 31.26
JHH-4 GDSC1; GDSC2 0.8948 2.9699 0.7602 25.0526
Huh-7 GDSC1; GDSC2 1.1043 3.9648 0.7 24.4057
JHH-7 GDSC1; GDSC2 1.831 6.4409 0.395 23.0086
JHH-2 GDSC1; GDSC2 1.9648 8.9117 -0.6713 27.5077
SNU-449 GDSC1; GDSC2 2.1243 8.0905 -0.1216 24.4957
SNU-398 GDSC1; GDSC2 2.4124 9.4462 -0.5277 25.3097
SNU-387 GDSC1; GDSC2 2.614 12.5937 -1.9164 29.7021
Hep-G2/C3A GDSC1; GDSC2 2.6892 10.3002 -0.7075 25.1397
SNU-423 GDSC1; GDSC2 2.7766 8.0746 0.4771 19.1811
HuH-1 GDSC1; GDSC2 3.6504 8.9747 0.7644 14.9176
HLE GDSC1; GDSC2 4.484 10.8634 0.4704 14.3197
JHH-6 GDSC1; GDSC2 6.7947 19.1975 -1.9411 19.4667
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-549 GDSC1; GDSC2 -1.7523 3.4393 -2.2482 50.7209
NCI-H2291 GDSC1; GDSC2 -1.4273 4.045 -2.0752 48.2175
EBC-1 GDSC1; GDSC2 -1.1454 1.4452 -1.1976 44.9836
HCC44 GDSC1; GDSC2 -0.9234 4.2524 -1.595 44.2131
NCI-H1437 GDSC1; GDSC2 -0.8723 7.6002 -2.8589 45.5095
HCC15 GDSC1; GDSC2 -0.8239 10.8463 -4.2784 46.3334
NCI-H292 GDSC1; GDSC2 -0.8043 5.725 -2.007 44.136
NCI-H2795 GDSC1; GDSC2 -0.7114 1.2917 -0.733 40.5701
NCI-H1915 GDSC1; GDSC2 -0.5599 3.0746 -0.8495 40.0568
NCI-H1666 GDSC1; GDSC2 -0.5521 8.4571 -2.9106 43.9919
LCLC-97TM1 GDSC1; GDSC2 -0.175 5.3238 -1.1805 38.8144
EPLC-272H GDSC1; GDSC2 0.1113 10.8964 -3.3878 41.7482
NCI-H1792 GDSC1; GDSC2 0.1514 2.5577 0.0365 32.3857
HOP-92 GDSC1; GDSC2 0.1606 5.0183 -0.7041 35.4848
Calu-6 GDSC1; GDSC2 0.3305 4.9279 -0.4881 33.7893
NCI-H2009 GDSC1; GDSC2 0.3834 6.0829 -0.9065 35.0779
SK-MES-1 GDSC1; GDSC2 0.4186 4.3252 -0.1678 31.9862
RERF-LC-MS GDSC1; GDSC2 0.6359 4.8355 -0.1271 30.7416
KNS-62 GDSC1; GDSC2 0.6524 4.6736 -0.0466 30.2909
NCI-H1734 GDSC2 0.7759 4.3498 0.2078 28.478
NCI-H2347 GDSC1; GDSC2 0.8306 13.2954 -3.8677 39.8124
NCI-H460 GDSC1; GDSC2 0.8355 12.1033 -3.2809 38.881
NCI-H3122 GDSC1; GDSC2 0.8744 5.2502 -0.0431 29.2374
HOP-62 GDSC1; GDSC2 0.9257 5.9305 -0.2809 30.0833
NCI-H2122 GDSC1; GDSC2 0.9318 2.8671 0.8221 24.5514
EMC-BAC-2 GDSC1; GDSC2 1.0948 7.6447 -0.8921 31.7982
Lu-99A GDSC1; GDSC2 1.2956 3.5603 1.0411 21.6856
NCI-H1944 GDSC1; GDSC2 1.3661 8.9933 -1.2724 32.018
NCI-H2405 GDSC1; GDSC2 1.385 9.8282 -1.659 33.1592
NCI-H358 GDSC1; GDSC2 1.397 6.6707 -0.1396 27.4096
NCI-H1975 GDSC1; GDSC2 1.456 6.5958 -0.0464 26.7284
LXF 289 GDSC1; GDSC2 1.503 4.2887 1.0091 20.9504
CAL-12T GDSC1; GDSC2 1.5364 8.6743 -0.9569 30.2437
SW1271 GDSC1; GDSC2 1.5429 8.3648 -0.8013 29.6292
RERF-LC-Sq1 GDSC1; GDSC2 1.5618 7.5412 -0.3883 27.8569
NCI-H2087 GDSC1; GDSC2 1.6931 7.0416 -0.0236 25.6646
NCI-H1755 GDSC1; GDSC2 1.694 5.3278 0.771 21.4984
PC-14 GDSC1; GDSC2 1.8309 5.845 0.6736 21.4978
EMC-BAC-1 GDSC1; GDSC2 1.8407 6.3867 0.4301 22.7847
NCI-H2228 GDSC1; GDSC2 1.8578 6.6314 0.3309 23.2416
COR-L23 GDSC1; GDSC2 1.9194 5.4793 0.9301 19.7022
NCI-H1568 GDSC1; GDSC2 1.9386 9.1669 -0.8206 28.2026
A-427 GDSC1; GDSC2 1.9582 7.2461 0.133 23.8717
NCI-H290 GDSC1; GDSC2 1.9637 10.9239 -1.6629 31.0648
NCI-H1623 GDSC1; GDSC2 1.969 8.5811 -0.5056 26.7985
NCI-H2373 GDSC1; GDSC2 2.0272 8.586 -0.4541 26.3614
Calu-3 GDSC1; GDSC2 2.0611 6.4727 0.6029 21.0069
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 2.1811 7.0967 0.4161 21.5769
NCI-H1869 GDSC1 2.2 9.0792 -1.1588 24.8564
Lu-65 GDSC1; GDSC2 2.2558 7.961 0.0633 23.1232
NCI-H513 GDSC1; GDSC2 2.3906 7.054 0.6324 19.6448
SK-LU-1 GDSC1 2.4888 7.5475 -0.1531 18.1064
COR-L105 GDSC1; GDSC2 2.4925 6.1764 1.1557 16.2616
NCI-H2023 GDSC1; GDSC2 2.5217 7.6031 0.4826 20.0101
NCI-H322M GDSC1; GDSC2 2.5283 7.9094 0.3373 20.7642
NCI-H2030 GDSC1; GDSC2 2.5799 10.622 -0.9635 26.5277
EKVX GDSC1; GDSC2 2.5894 10.21 -0.7502 25.6455
NCI-H1573 GDSC1; GDSC2 2.6832 8.4145 0.2256 20.8211
NCI-H2227 GDSC1; GDSC2 2.7403 9.3536 -0.1913 22.6866
NCI-H2369 GDSC1; GDSC2 2.7709 6.8567 1.0766 15.786
LC-2/ad GDSC1; GDSC2 2.7886 4.998 2.0065 10.0203
NCI-H727 GDSC1; GDSC2 2.8641 20.6284 -5.7157 36.7494
NCI-H2110 GDSC1; GDSC2 2.8648 8.2311 0.4767 18.8946
NCI-H1299 GDSC1; GDSC2 2.9111 9.7067 -0.219 22.2609
NCI-H23 GDSC1; GDSC2 2.9496 8.9845 0.1747 20.2101
HCC78 GDSC1; GDSC2 2.9505 9.3257 0.0051 21.0578
NCI-H1563 GDSC1; GDSC2 2.9522 7.4811 0.9267 16.0799
NCI-H1355 GDSC1; GDSC2 2.9561 10.6693 -0.6609 24.085
NCI-H510A GDSC1; GDSC2 3.0194 8.2815 0.5857 17.8029
NCI-H2591 GDSC1; GDSC2 3.1213 12.1207 -1.2457 25.8843
NCI-H1648 GDSC1; GDSC2 3.1745 8.7231 0.4975 17.8016
NCI-H1993 GDSC1; GDSC2 3.2114 5.4046 2.1871 7.5128
NCI-H2135 GDSC1; GDSC2 3.2793 4.4442 2.7249 3.9057
NCI-H2810 GDSC1; GDSC2 3.3535 11.0013 -0.4915 22.1302
LK-2 GDSC1; GDSC2 3.4887 6.3485 1.9453 8.238
NCI-H211 GDSC1; GDSC2 3.5297 5.3754 2.4628 4.8649
NCI-H647 GDSC1; GDSC2 3.5338 11.7507 -0.7172 22.573
SHP-77 GDSC1; GDSC2 3.5751 4.9584 2.7039 3.2353
RERF-LC-KJ GDSC1; GDSC2 3.593 8.4887 0.9608 13.9546
IA-LM GDSC1; GDSC2 3.6271 9.6946 0.3862 17.055
NCI-H2461 GDSC1; GDSC2 3.6367 11.2009 -0.3585 20.7016
NCI-H2731 GDSC1; GDSC2 3.64 9.6149 0.4364 16.7509
BEN GDSC1; GDSC2 3.6563 5.6259 2.4354 4.7126
NCI-H2066 GDSC1; GDSC2 3.7183 6.1222 2.2369 5.7994
NCI-H1703 GDSC1; GDSC2 3.7984 6.1696 2.2731 5.3768
NCI-H1688 GDSC1; GDSC2 3.8423 8.1337 1.3348 11.0565
NCI-H3255 GDSC1; GDSC2 3.8659 11.7521 -0.4488 20.462
Lu-165 GDSC1; GDSC2 3.8694 5.5891 2.6058 3.1678
NCI-H1793 GDSC1; GDSC2 3.8813 9.2136 0.8283 13.9189
NCI-H446 GDSC1; GDSC2 3.904 6.6839 2.0979 6.2097
Ms-1 GDSC1; GDSC2 3.9472 5.781 2.5663 3.2424
LC-1/sq GDSC1; GDSC2 3.9561 9.8749 0.5578 15.2187
SBC-3 GDSC1; GDSC2 3.9725 6.998 1.9938 6.6897
NCI-H82 GDSC1; GDSC2 3.9764 5.4759 2.7292 2.2221
PaCa-3 GDSC1; GDSC2 3.9849 8.5998 1.2131 11.4107
NCI-H1435 GDSC1; GDSC2 4.0066 8.725 1.1677 11.6233
NCI-H2722 GDSC1; GDSC2 4.0126 8.3719 1.3469 10.5427
NCI-H1581 GDSC1; GDSC2 4.0339 14.3726 -1.6219 24.646
NCI-H524 GDSC1; GDSC2 4.0568 6.8968 2.1037 5.8175
NCI-H650 GDSC1; GDSC2 4.0703 11.784 -0.3027 19.2364
NCI-H2170 GDSC1; GDSC2 4.1389 6.1534 2.5153 3.1628
SBC-5 GDSC1; GDSC2 4.1457 10.2379 0.5242 14.8959
LCLC-103H GDSC1; GDSC2 4.1677 5.7679 2.7112 1.9905
NCI-H1304 GDSC1 4.2037 5.7851 1.7972 0.6356
NCI-H810 GDSC1; GDSC2 4.2179 6.0563 2.6096 2.4746
NCI-H1781 GDSC1; GDSC2 4.2209 6.6865 2.3169 4.1745
NCI-H596 GDSC1; GDSC2 4.2677 13.0485 -0.7774 20.7991
DMS 53 GDSC1; GDSC2 4.3031 9.1644 1.1726 10.8504
NCI-H2804 GDSC1; GDSC2 4.3116 8.9888 1.265 10.2888
NCI-H187 GDSC1 4.3664 5.573 1.9347 0.1639
NCI-H1836 GDSC1; GDSC2 4.3978 5.941 2.7631 1.379
COR-L279 GDSC1; GDSC2 4.4012 6.4526 2.5383 2.5638
NCI-H2803 GDSC2 4.4231 10.8822 0.4157 14.7611
NCI-H1876 GDSC1; GDSC2 4.4234 7.7152 1.9616 5.8788
IST-SL1 GDSC1; GDSC2 4.442 6.8869 2.3639 3.478
NCI-H522 GDSC1; GDSC2 4.4451 7.8506 1.9114 6.1327
NCI-H1838 GDSC1; GDSC2 4.4814 8.7756 1.4905 8.5608
COR-L88 GDSC1; GDSC2 4.4827 6.7866 2.4347 3.0049
NCI-H1963 GDSC2 4.5028 7.2787 2.2198 4.1974
NCI-H1694 GDSC1; GDSC2 4.5181 7.8522 1.9593 5.697
NCI-H1693 GDSC1; GDSC2 4.5546 14.078 -1.0665 21.2356
NCI-H1105 GDSC1; GDSC2 4.6 6.5461 2.6091 1.8849
COR-L32 GDSC1; GDSC2 4.6231 9.4525 1.2617 9.5814
NCI-H226 GDSC1; GDSC2 4.6612 11.4505 0.3126 14.7064
ChaGo-K-1 GDSC1; GDSC2 4.6638 7.5203 2.2077 3.9731
NCI-H146 GDSC1; GDSC2 4.6795 6.7195 2.5766 1.9416
NCI-H2171 GDSC2 4.7027 6.8318 2.5402 2.0959
NCI-H2869 GDSC1; GDSC2 4.7052 8.7219 1.6695 7.021
Lu-135 GDSC1; GDSC2 4.7155 6.7273 2.5924 1.8141
NCI-H196 GDSC1; GDSC2 4.725 7.9472 2.0478 4.7777
NCI-H2818 GDSC1; GDSC2 4.7328 9.1645 1.4764 8.0919
NCI-H2196 GDSC2 4.7462 7.369 2.326 3.1718
HCC366 GDSC1; GDSC2 4.7947 10.3507 0.9464 10.9863
NCI-H520 GDSC1; GDSC2 4.875 9.3005 1.5068 7.6175
NCI-H69 GDSC1; GDSC2 4.8873 11.9036 0.2554 14.4561
LOU-NH91 GDSC1; GDSC2 4.8989 14.2566 -0.8933 19.6868
NCI-H2085 GDSC1; GDSC2 4.9145 14.8747 -1.1869 20.8172
NCI-H250 GDSC2 4.9541 8.9148 1.7406 6.1135
NCI-H526 GDSC1; GDSC2 4.9575 11.1084 0.6932 12.0056
COLO 668 GDSC1; GDSC2 4.9613 15.7499 -1.5843 22.1802
ABC-1 GDSC1; GDSC2 4.9679 8.5679 1.9108 5.1163
UMC-11 GDSC1; GDSC2 5.0504 7.0542 2.6237 1.2811
NCI-H345 GDSC1; GDSC2 5.0924 5.7408 3.117 0.0073
NCI-H838 GDSC1; GDSC2 5.1138 18.2377 -2.7003 25.3905
NCI-H1650 GDSC1; GDSC2 5.1463 8.0117 2.2662 2.8857
NCI-H1436 GDSC1; GDSC2 5.1724 6.7609 2.7934 0.5405
NCI-H64 GDSC1; GDSC2 5.1782 6.3078 2.9587 0.1376
COR-L303 GDSC2 5.192 6.755 2.8037 0.4973
NCI-H847 GDSC1; GDSC2 5.195 13.2012 -0.157 15.7492
DMS 114 GDSC1; GDSC2 5.2113 10.7376 1.0459 9.529
NCI-H720 GDSC1; GDSC2 5.2203 6.3927 2.9445 0.1505
NCI-H209 GDSC1; GDSC2 5.2342 8.6457 2.0342 3.9821
NCI-H2172 GDSC1; GDSC2 5.2445 9.1673 1.8036 5.2294
NCI-H2029 GDSC1; GDSC2 5.3013 11.1622 0.9034 10.1217
CPC-N GDSC1; GDSC2 5.3196 7.3582 2.6265 1.0228
NCI-H661 GDSC1; GDSC2 5.3439 8.6615 2.0894 3.5214
SW1573 GDSC1; GDSC2 5.3546 12.9778 0.0652 14.3273
DMS 273 GDSC1; GDSC2 5.3594 11.3726 0.8418 10.3338
COR-L321 GDSC1; GDSC2 5.3961 6.9868 2.7998 0.4026
NCI-H841 GDSC1; GDSC2 5.4713 13.5526 -0.1317 15.0072
NCI-H748 GDSC2 5.5544 7.549 2.6547 0.7474
DMS 79 GDSC1; GDSC2 5.587 7.1452 2.816 0.286
VMRC-LCD GDSC1; GDSC2 5.6369 7.9074 2.5521 1.0486
NCI-H2141 GDSC1; GDSC2 5.6518 7.4657 2.7255 0.4787
NCI-H1092 GDSC1; GDSC2 5.6775 7.6214 2.6783 0.5988
NCI-H2595 GDSC1; GDSC2 5.6877 12.3995 0.5711 11.0839
COR-L95 GDSC1; GDSC2 5.6995 7.5556 2.7115 0.4934
COR-L311 GDSC2 5.7294 7.7674 2.6451 0.6696
LB647-SCLC GDSC1; GDSC2 5.7439 7.3748 2.7934 0.2798
HCC33 GDSC2 5.8357 7.5094 2.78 0.2769
NCI-H2081 GDSC1; GDSC2 5.8374 8.3299 2.4755 1.1764
SBC-1 GDSC1; GDSC2 5.9255 12.431 0.7113 9.8921
HCC827 GDSC1; GDSC2 5.9376 14.863 -0.4409 15.4067
IST-SL2 GDSC1; GDSC2 6.0047 11.5188 1.1848 7.271
NCI-H2342 GDSC1; GDSC2 6.1222 8.2373 2.6288 0.5129
NCI-H740 GDSC2 6.1669 8.391 2.5903 0.5935
NCI-H1341 GDSC1; GDSC2 6.1842 16.2238 -0.9274 16.9466
NCI-H1155 GDSC1; GDSC2 6.2034 15.1252 -0.3853 14.6118
NCI-H1770 GDSC1; GDSC2 6.2565 17.9843 -1.7309 19.8245
NCI-H2444 GDSC1; GDSC2 6.3421 15.5403 -0.4905 14.7933
NCI-H835 GDSC1; GDSC2 6.3449 8.2708 2.7006 0.2752
NCI-H1048 GDSC1; GDSC2 6.5729 16.9074 -0.9896 16.4088
Lu-134-A GDSC1; GDSC2 6.5874 8.8641 2.5818 0.4355
NCI-H441 GDSC1; GDSC2 7.1575 19.1534 -1.6704 17.8353
NCI-H1651 GDSC1; GDSC2 7.3804 21.6447 -2.7173 20.8157
Lu-139 GDSC1; GDSC2 7.5944 20.2287 -1.8906 17.7949
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 4.7056 6.9058 2.5094 2.2512
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EC-GI-10 GDSC1; GDSC2 0.3745 5.8331 -0.8097 34.784
OE21 GDSC1; GDSC2 0.8455 5.3953 -0.134 29.7908
TE-15 GDSC1; GDSC2 1.0104 12.4855 -3.3047 38.3074
TE-4 GDSC1; GDSC2 1.2352 3.7021 0.9305 22.5631
TE-8 GDSC1; GDSC2 1.3605 8.1374 -0.8669 30.6062
KYSE-520 GDSC1; GDSC2 1.5219 7.4036 -0.3614 27.8989
KYSE-410 GDSC1; GDSC2 1.7341 9.9566 -1.3965 31.0314
KYSE-140 GDSC1; GDSC2 1.8226 5.02 1.0387 19.459
OE33 GDSC1; GDSC2 2.0474 5.2726 1.1529 17.9122
TE-5 GDSC1; GDSC2 2.6468 7.8207 0.4878 19.5556
KYSE-450 GDSC1; GDSC2 2.7869 8.0485 0.4992 19.027
KYSE-150 GDSC1; GDSC2 2.9453 6.9737 1.1734 14.6412
TE-1 GDSC1; GDSC2 3.2337 11.4255 -0.8036 23.8218
TE-6 GDSC1; GDSC2 3.9512 9.3271 0.8263 13.7423
TE-10 GDSC1; GDSC2 4.0966 15.0312 -1.9003 25.4193
KYSE-510 GDSC1; GDSC2 4.2723 8.2795 1.5836 8.4854
OE19 GDSC1; GDSC2 4.2804 11.8355 -0.1648 18.0317
T.T GDSC1; GDSC2 4.4454 12.9638 -0.5977 19.5704
TE-11 GDSC1; GDSC2 4.5929 10.6094 0.6755 12.9528
KYSE-270 GDSC1; GDSC2 4.7037 12.0462 0.0509 15.9173
KYSE-70 GDSC1; GDSC2 5.6343 17.0965 -1.7461 21.2062
KYSE-180 GDSC1; GDSC2 5.9457 12.5447 0.6709 10.0616
TE-9 GDSC1; GDSC2 6.7175 21.7547 -3.2407 23.5418
COLO 680N GDSC1; GDSC2 6.9432 18.3207 -1.4163 17.3238
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OV-90 GDSC1; GDSC2 -2.5919 0.8921 -2.6663 58.5329
OVCAR-5 GDSC1; GDSC2 -1.6827 4.5712 -2.5256 50.156
JHOS-2 GDSC1; GDSC2 -0.3814 5.461 -1.4537 40.6634
TYK-nu GDSC1; GDSC2 -0.2148 4.8547 -1.043 38.6322
ES-2 GDSC1; GDSC2 -0.0709 5.4606 -1.1244 38.0908
IGROV-1 GDSC1; GDSC2 0.3313 6.8998 -1.3168 36.6287
EFO-27 GDSC1; GDSC2 1.1014 6.4631 -0.3398 29.5631
OV56 GDSC1; GDSC2 1.4013 6.7779 -0.1852 27.6018
Caov-4 GDSC1; GDSC2 1.4302 6.5126 -0.0334 26.7726
TOV-21G GDSC1; GDSC2 1.7077 7.0782 -0.0268 25.6222
OVK18 GDSC1; GDSC2 1.8666 12.81 -2.6836 34.1576
OVTOKO GDSC1; GDSC2 1.9541 6.6371 0.4213 22.3956
OAW42 GDSC1 1.9607 6.7296 -0.1897 20.3651
DOV13 GDSC1; GDSC2 2.2044 12.6556 -2.3061 32.1161
A2780 GDSC1; GDSC2 2.5134 4.2582 2.0816 10.5711
OVCAR-4 GDSC1; GDSC2 2.7027 8.148 0.3752 19.9726
JHOS-4 GDSC1; GDSC2 2.8096 7.1278 0.9768 16.2476
OVCAR-8 GDSC1; GDSC2 3.182 10.5367 -0.4027 22.2542
OVISE GDSC1; GDSC2 3.2551 10.126 -0.1359 20.7912
Caov-3 GDSC2 3.3687 9.1904 0.4266 17.595
TOV-112D GDSC1; GDSC2 3.477 8.1964 1.0127 13.9836
OC 314 GDSC1; GDSC2 3.5722 9.1917 0.5929 16.0963
OAW28 GDSC1; GDSC2 3.5796 9.3753 0.5072 16.5432
RMG-I GDSC1; GDSC2 3.8292 17.5871 -3.3925 30.2473
FU-OV-1 GDSC1; GDSC2 4.396 13.9681 -1.1347 21.9067
EFO-21 GDSC1; GDSC2 4.4564 9.9567 0.8959 12.0636
OVKATE GDSC1; GDSC2 5.4515 12.0835 0.5637 11.6109
Kuramochi GDSC1; GDSC2 5.7461 14.7155 -0.5029 16.0876
SK-OV-3 GDSC1; GDSC2 5.7534 13.4161 0.1293 13.1559
OVCAR-3 GDSC1; GDSC2 6.7445 14.6142 0.2094 10.8502
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PSN1 GDSC1; GDSC2 -2.1006 1.2289 -2.1829 54.0935
KP-2 GDSC1; GDSC2 -1.5333 7.3525 -3.4392 49.2997
Panc 02.03 GDSC1; GDSC2 -1.0759 4.359 -1.796 45.5225
SUIT-2 GDSC1; GDSC2 -0.663 5.4649 -1.7548 42.8997
HuP-T4 GDSC1; GDSC2 -0.273 10.2799 -3.471 43.3978
HPAF-II GDSC1 -0.1535 3.0866 -0.6212 33.6672
PaTu 8902 GDSC1; GDSC2 0.006 5.9789 -1.2555 38.0667
MIA PaCa-2 GDSC1; GDSC2 0.0595 5.4519 -0.9831 36.967
PL4 GDSC1; GDSC2 0.2067 4.9642 -0.634 34.9869
AsPC-1 GDSC1; GDSC2 0.3656 7.6164 -1.6042 37.2642
Panc 03.27 GDSC1; GDSC2 0.4547 9.912 -2.5873 39.0838
HPAC GDSC1; GDSC2 0.8047 6.7459 -0.7672 32.6036
Panc 04.03 GDSC1; GDSC2 0.8852 11.1558 -2.7737 37.7725
MZ-PC-1 GDSC1; GDSC2 0.889 9.5563 -1.9988 36.0296
BxPC-3 GDSC1; GDSC2 0.9776 7.1735 -0.7889 31.9187
PaTu 8988t GDSC1; GDSC2 1.4461 10.3088 -1.8359 33.4417
DAN-G GDSC1; GDSC2 1.4574 7.373 -0.4096 28.3695
Hs 766T GDSC1; GDSC2 1.6909 14.1101 -3.4852 36.3965
Panc 10.05 GDSC1; GDSC2 1.7469 15.1346 -3.9434 37.0357
KP-3 GDSC1; GDSC2 1.9774 6.1041 0.6968 20.8025
HuP-T3 GDSC1; GDSC2 2.0005 10.825 -1.5807 30.6773
CFPAC-1 GDSC1; GDSC2 2.4766 8.7193 -0.1099 23.1899
Capan-1 GDSC1; GDSC2 2.5039 9.3988 -0.4226 24.5364
QGP-1 GDSC1; GDSC2 2.6564 15.1543 -3.1576 32.8347
Capan-2 GDSC1 2.9434 23.9772 -7.9923 38.32
SW1990 GDSC1; GDSC2 2.9822 8.487 0.451 18.6558
SU.86.86 GDSC1; GDSC2 3.0493 9.0088 0.2482 19.5154
KP-4 GDSC1; GDSC2 3.8611 10.478 0.1827 17.453
KP-1N GDSC1; GDSC2 4.5692 11.8743 0.0355 16.3256
Panc 08.13 GDSC1; GDSC2 4.8147 10.2079 1.0297 10.4747
YAPC GDSC1; GDSC2 5.8491 16.4277 -1.2628 18.9747
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2 2.014 7.7653 -0.0658 24.6365
MPP 89 GDSC1; GDSC2 3.371 13.5097 -1.7311 26.8453
NCI-H2452 GDSC1; GDSC2 4.5278 14.5697 -1.3313 22.32
NCI-H2052 GDSC1; GDSC2 5.0761 14.7275 -0.9932 19.6678
NCI-H28 GDSC1; GDSC2 5.4517 18.921 -2.7816 24.8687
IST-Mes1 GDSC1; GDSC2 7.5974 22.2127 -2.8414 20.7863
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC1; GDSC2 0.8773 7.7215 -1.1423 33.6026
LNCaP clone FGC GDSC1; GDSC2 4.2973 6.5383 2.4357 3.3282
VCaP GDSC1; GDSC2 4.6173 6.797 2.5083 2.3868
NCI-H660 GDSC2 5.2549 6.7628 2.826 0.4001
22Rv1 GDSC1; GDSC2 5.8936 17.7601 -1.8822 21.1102
PC-3 GDSC1; GDSC2 6.4652 13.3989 0.5998 9.4605
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 2.3287 9.2468 -0.5041 25.4983
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IGR-37 GDSC1; GDSC2 -5.2997 0.603 -5.5084 74.8063
CP50-MEL-B GDSC1; GDSC2 -4.8209 6.0853 -6.4475 64.3234
IPC-298 GDSC1; GDSC2 -4.5294 0.4866 -4.6714 71.8667
G-mel GDSC1; GDSC2 -4.4196 -1.2433 -4.4332 74.9326
M14 GDSC1 -4.3722 1.8013 -4.8483 69.6558
COLO 679 GDSC1; GDSC2 -3.4797 6.9422 -5.3287 58.7118
451Lu GDSC1; GDSC2 -3.2344 2.1878 -3.5585 61.9224
LB2518-MEL GDSC1; GDSC2 -3.1579 3.6164 -3.8323 59.9365
Mel Ho GDSC1; GDSC2 -3.0927 6.6073 -4.7866 57.2988
WT2-iPS GDSC1; GDSC2 -3.0047 0.1839 -3.0413 62.5324
HT-144 GDSC1; GDSC2 -2.9786 3.6282 -3.64 58.9126
UACC-257 GDSC1; GDSC2 -2.9756 0.7394 -3.0553 61.765
A-375 GDSC1; GDSC2 -2.9685 0.7058 -3.0445 61.7428
SH-4 GDSC1; GDSC2 -2.9589 3.0638 -3.4638 59.3045
WM35 GDSC1; GDSC2 -2.7944 4.239 -3.6243 57.3709
CP66-MEL GDSC1; GDSC2 -2.7728 7.5605 -4.8256 55.3959
SK-MEL-28 GDSC1; GDSC2 -2.5479 3.3833 -3.1009 56.4486
SK-MEL-30 GDSC1; GDSC2 -2.343 2.4725 -2.6509 55.5545
MZ-MEL-7 GDSC1; GDSC2 -2.0496 8.0172 -4.2577 51.9349
SK-MEL-2 GDSC1; GDSC2 -1.9263 2.9126 -2.2992 52.1626
LOX-IMVI GDSC1; GDSC2 -1.8821 4.2145 -2.6241 51.5898
MMAc-SF GDSC1; GDSC2 -1.8292 18.1922 -8.7463 50.4515
G-361 GDSC1; GDSC2 -1.6989 3.4978 -2.2064 50.3009
Hs 938.T GDSC1; GDSC2 -1.372 11.2905 -5.0275 48.8208
A101D GDSC1; GDSC2 -1.2327 8.4852 -3.6162 47.8095
HMV-II GDSC1; GDSC2 -1.218 4.2114 -1.9013 46.6063
GAK GDSC1; GDSC2 -1.0195 3.5844 -1.4903 44.6721
RVH-421 GDSC1; GDSC2 -1.0053 5.8797 -2.2814 45.6605
MZ-MEL-2 GDSC1; GDSC2 -0.9458 4.9693 -1.8704 44.7895
WM115 GDSC1; GDSC2 -0.6346 5.7199 -1.8249 42.8624
COLO 792 GDSC1; GDSC2 -0.5664 12.6031 -4.8555 45.692
WM278 GDSC1; GDSC2 -0.5314 24.0174 -10.3897 47.5164
SK-MEL-5 GDSC1; GDSC2 -0.5298 7.4771 -2.4527 43.2955
Mel JuSo GDSC1; GDSC2 -0.36 4.7893 -1.1746 39.8313
RPMI-7951 GDSC1; GDSC2 -0.3139 11.3328 -4.0072 44.104
SK-MEL-1 GDSC1; GDSC2 -0.2103 6.4642 -1.6856 40.2754
COLO 829 GDSC1; GDSC2 0.1148 11.7236 -3.7797 42.2298
MeWo GDSC1; GDSC2 0.3087 4.4286 -0.3235 33.2204
COLO 783 GDSC1; GDSC2 0.4966 5.4362 -0.5163 33.0796
LB373-MEL-D GDSC1; GDSC2 0.8311 11.7111 -3.0942 38.5728
CHL-1 GDSC1; GDSC2 0.8546 7.1664 -0.9084 32.8966
COLO 800 GDSC1; GDSC2 0.9676 12.1584 -3.1846 38.2458
SK-MEL-3 GDSC1; GDSC2 1.4582 13.1148 -3.2029 36.6071
WM1552C GDSC1; GDSC2 1.4707 13.607 -3.4346 37.0017
WM793 GDSC1; GDSC2 1.5208 10.4547 -1.8378 33.171
IST-MEL1 GDSC1; GDSC2 1.863 10.8339 -1.7098 31.5622
SK-MEL-24 GDSC1; GDSC2 1.9315 20.7746 -6.5886 39.9483
A-431 GDSC1; GDSC2 2.0498 8.4762 -0.3794 25.9507
A2058 GDSC1; GDSC2 2.1589 8.1787 -0.1328 24.4227
IGR-1 GDSC1; GDSC2 2.5501 8.9413 -0.1543 23.1491
A-388 GDSC1; GDSC2 2.7229 10.6417 -0.8483 25.6045
UACC-62 GDSC1; GDSC2 2.7292 9.7776 -0.4123 23.7364
DJM-1 GDSC1; GDSC2 3.0657 9.2418 0.1458 19.9888
Hs 940.T GDSC1; GDSC2 3.3839 5.7869 2.1407 7.2994
SK-MEL-31 GDSC1; GDSC2 4.1002 12.5726 -0.6719 20.798
VMRC-MELG GDSC2 4.1254 7.6695 1.776 7.6645
EquiPSC Line K2 GDSC1; GDSC2 -2.1265 5.8405 -3.4615 52.7848
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 0.8634 5.208 -0.0371 29.2597
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC1; GDSC2 -0.8974 5.5447 -2.0355 44.7241
SK-LMS-1 GDSC1; GDSC2 0.2523 3.7375 -0.1501 32.7456
HT-1080 GDSC1; GDSC2 0.5473 5.8717 -0.6462 33.342
SW872 GDSC1; GDSC2 0.5507 10.4068 -2.7307 38.9703
MFH-ino GDSC1; GDSC2 0.5985 7.9065 -1.5045 35.939
SW982 GDSC1; GDSC2 0.6077 11.2021 -3.0586 39.337
G-401 GDSC1; GDSC2 0.798 4.8438 0.0418 29.1874
RKN GDSC1; GDSC2 1.4178 8.8688 -1.1632 31.4449
STS-0421 GDSC1; GDSC2 1.6629 5.825 0.515 23.0325
RD GDSC1; GDSC2 2.2471 12.7961 -2.3382 32.0648
A-204 GDSC1; GDSC2 2.4931 6.928 0.7889 18.4042
G-402 GDSC1; GDSC2 3.18 11.6054 -0.9387 24.5306
VA-ES-BJ GDSC1; GDSC2 3.4028 6.9086 1.5955 10.6683
Rh18 GDSC1 3.5178 12.9873 -2.0499 24.3562
MES-SA GDSC1; GDSC2 3.7078 7.4373 1.5763 9.9417
Rh41 GDSC1; GDSC2 3.936 6.5576 2.1829 5.6088
EW-8 GDSC1; GDSC2 4.2136 6.7827 2.2664 4.4908
SW684 GDSC1; GDSC2 4.8087 16.1458 -1.897 23.6243
GCT GDSC1; GDSC2 4.9859 16.2256 -1.8011 22.8775
TE 441.T GDSC2 5.2805 6.4682 2.9401 0.1429
Rh30 GDSC1; GDSC2 5.8469 8.4206 2.444 1.2881
KYM-1 GDSC1; GDSC2 6.4575 18.7126 -1.9427 20.1418
SK-UT-1 GDSC1; GDSC2 6.8883 17.5059 -1.0632 16.0851
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUM-1 GDSC1; GDSC2 -4.0175 0.6383 -4.1462 68.8986
AGS GDSC1; GDSC2 -2.3549 2.213 -2.6096 55.7883
TMK-1 GDSC1; GDSC2 0.2843 8.4664 -2.0757 38.7644
RERF-GC-1B GDSC1; GDSC2 0.4692 7.2992 -1.3559 36.0957
GCIY GDSC1; GDSC2 0.8334 6.2343 -0.5091 31.4667
SNU-5 GDSC1; GDSC2 0.9606 10.0511 -2.1681 36.1622
Fu97 GDSC1; GDSC2 1.3072 7.8894 -0.8003 30.5704
ECC10 GDSC1; GDSC2 1.4783 5.6392 0.4126 24.3318
MKN45 GDSC1; GDSC2 1.5317 6.6362 0.0096 26.1505
MKN28 GDSC1; GDSC2 1.7886 7.8123 -0.3013 26.5836
TGBC11TKB GDSC1; GDSC2 1.8148 9.4434 -1.0705 29.604
Hs 746.T GDSC1; GDSC2 1.9164 6.3828 0.5057 22.087
NUGC-3 GDSC1; GDSC2 2.0518 8.8434 -0.5576 26.7153
KATO III GDSC1; GDSC2 2.1415 5.8265 0.9879 18.5211
23132/87 GDSC1; GDSC2 2.1819 7.3576 0.2899 22.2391
NUGC-4 GDSC1; GDSC2 2.2649 10.3432 -1.1044 28.1232
HSC-39 GDSC1; GDSC2 2.3789 4.2882 1.9304 12.0008
SNU-1 GDSC1; GDSC2 2.7732 7.605 0.7075 17.9181
SK-GT-2 GDSC1; GDSC2 2.8451 6.9257 1.1088 15.3512
NCI-N87 GDSC1 3.1092 6.9068 0.6479 10.4768
SNU-16 GDSC1; GDSC2 3.5407 5.0074 2.6538 3.635
MKN7 GDSC1; GDSC2 3.5798 13.1288 -1.3683 24.991
ECC12 GDSC2 4.8689 6.5189 2.755 0.9042
SCH GDSC1; GDSC2 5.1349 15.2795 -1.2214 20.4258
IM95 GDSC1; GDSC2 5.3681 13.5941 -0.2249 15.6715
MKN1 GDSC1; GDSC2 5.4631 14.0786 -0.3933 16.2245
RF-48 GDSC1; GDSC2 5.939 14.5606 -0.2942 14.7492
HGC-27 GDSC1; GDSC2 6.7679 14.7945 0.1401 11.1331
SNG-M GDSC1; GDSC2 4.4907 16.1988 -2.1703 25.2822
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1; GDSC2 -3.6895 1.1049 -3.8583 66.1926
K5 GDSC1; GDSC2 -2.7367 3.685 -3.3926 57.4325
BHT-101 GDSC1; GDSC2 -2.575 0.4323 -2.6113 58.6738
HTC-C3 GDSC1; GDSC2 -1.8732 5.4021 -3.0262 51.3581
IHH-4 GDSC1; GDSC2 -1.0453 3.7341 -1.5628 44.9719
TT2609-C02 GDSC1; GDSC2 -0.8519 4.8821 -1.7376 44.0015
ASH-3 GDSC1; GDSC2 0.0042 5.8017 -1.1839 37.8704
CAL-62 GDSC1; GDSC2 0.8395 6.06 -0.4261 31.0963
8305C GDSC1; GDSC2 1.1026 15.7072 -4.8053 40.1908
B-CPAP GDSC1; GDSC2 1.3935 7.9052 -0.7243 29.9246
8505C GDSC1; GDSC2 1.7521 8.4721 -0.6552 28.2387
ML-1 [Human leukemia] GDSC1; GDSC2 2.1718 5.5732 1.1369 17.5341
CGTH-W-1 GDSC1; GDSC2 3.0115 10.1593 -0.3587 22.5855
TT GDSC1; GDSC2 3.8571 6.4385 2.1841 5.788
WRO GDSC1; GDSC2 3.863 10.0862 0.3794 16.428
FTC-133 GDSC1; GDSC2 4.5231 13.1403 -0.6257 19.493
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H3118 GDSC1; GDSC2 -3.6038 8.3558 -6.0253 58.2782
DOK GDSC1; GDSC2 -2.7085 16.8386 -8.9431 52.867
JHU-022 GDSC1; GDSC2 -1.3913 21.8135 -10.0954 49.3742
UPCI-SCC-090 GDSC1; GDSC2 -0.9419 6.4153 -2.4304 45.4555
HSC-3 GDSC1; GDSC2 -0.4346 4.234 -1.0587 39.9397
BICR 78 GDSC1; GDSC2 -0.3655 6.0724 -1.6837 41.0926
BICR 22 GDSC1; GDSC2 -0.2733 3.3288 -0.6035 37.4838
JHU-011 GDSC1; GDSC2 -0.024 8.666 -2.4746 40.925
BB30-HNC GDSC1; GDSC2 0.0775 5.2192 -0.8712 36.5044
HO-1-N-1 GDSC1; GDSC2 0.1556 4.2178 -0.4139 34.3879
PCI-04B GDSC1; GDSC2 0.2159 5.5208 -0.8461 35.7046
PE/CA-PJ15 GDSC1; GDSC2 0.3071 5.8198 -0.8743 35.3435
CAL-33 GDSC1; GDSC2 0.4301 8.106 -1.7641 37.3828
Ca9-22 GDSC1; GDSC2 0.5826 4.613 -0.0979 30.8639
JHU-029 GDSC1; GDSC2 0.6092 6.3096 -0.772 33.5207
CAL-27 GDSC1; GDSC2 0.7816 6.94 -0.8782 33.1141
SCC-25 GDSC1; GDSC2 0.7938 7.887 -1.3019 34.4782
SAS GDSC1; GDSC2 0.8509 8.1214 -1.3552 34.3967
PCI-15A GDSC1; GDSC2 0.8619 7.6461 -1.1225 33.6034
PCI-38 GDSC1 0.9464 7.0578 -1.2714 30.676
KON GDSC1; GDSC2 0.9643 7.3528 -0.8849 32.3314
BB49-HNC GDSC1 0.9658 11.0968 -3.2412 36.8016
HSC-4 GDSC1; GDSC2 1.0391 8.6765 -1.4341 33.8497
KOSC-2 GDSC1; GDSC2 1.0775 6.4515 -0.3586 29.7487
FaDu GDSC1; GDSC2 1.5128 12.0888 -2.6475 35.26
OSC-19 GDSC1; GDSC2 1.5959 7.2908 -0.2361 27.0436
SAT [Human HNSCC] GDSC1; GDSC2 2.0744 14.865 -3.5196 35.2935
HSC-2 GDSC1; GDSC2 2.3069 8.6117 -0.2101 24.2546
SKN-3 GDSC1; GDSC2 2.3552 10.4728 -1.088 27.7539
BICR 10 GDSC1 2.4707 7.8638 -0.326 19.2607
BHY GDSC1; GDSC2 2.5496 7.5537 0.5323 19.6438
SCC-4 GDSC1; GDSC2 2.7591 10.6715 -0.8318 25.4209
Detroit 562 GDSC1; GDSC2 2.8033 8.081 0.4974 18.9828
PCI-06A GDSC1; GDSC2 2.8375 9.5103 -0.1847 22.3373
BICR 31 GDSC2 3.404 9.9423 0.0799 19.286
OSC-20 GDSC1; GDSC2 3.8696 10.9934 -0.0675 18.6728
SCC-15 GDSC1; GDSC2 4.3868 15.209 -1.7592 24.2023
PCI-30 GDSC1; GDSC2 4.5085 7.8764 1.9414 5.8224
SCC-9 GDSC1; GDSC2 4.6463 20.3574 -4.1188 29.946
HO-1-u-1 GDSC1; GDSC2 4.8449 14.6183 -1.1127 20.6974
LB771-HNC GDSC1; GDSC2 4.9624 9.1378 1.6411 6.6687
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC1; GDSC2 -1.6063 2.9807 -1.9672 49.5467
BFTC-905 GDSC1; GDSC2 -0.2564 1.7106 -0.2887 36.0656
SW780 GDSC1; GDSC2 0.8301 6.559 -0.6573 32.0708
RT-112 GDSC1; GDSC2 0.9276 6.6079 -0.5806 31.3314
SW1710 GDSC1; GDSC2 1.1202 6.0043 -0.1145 28.4705
CAL-29 GDSC1; GDSC2 1.5797 9.6064 -1.3687 31.5139
UM-UC-3 GDSC1; GDSC2 2.9571 8.2177 0.5638 18.1215
5637 GDSC1; GDSC2 3.5617 9.5023 0.4292 17.014
RT-4 GDSC1; GDSC2 3.6515 7.3284 1.5863 10.0317
639V GDSC1; GDSC2 4.0135 9.8496 0.615 14.7526
TCCSUP GDSC1; GDSC2 4.6105 12.3999 -0.193 17.3203
HT-1197 GDSC1; GDSC2 4.615 12.6588 -0.3176 17.8879
T24 GDSC1; GDSC2 5.0167 11.6632 0.4654 13.0768
HT-1376 GDSC1; GDSC2 5.1442 14.8033 -0.9799 19.4538
647V GDSC1; GDSC2 6.294 17.8537 -1.6407 19.4286
J82 GDSC1; GDSC2 6.6927 23.2952 -4.0138 25.5338
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BPH-1 GDSC1; GDSC2 -1.6262 6.4269 -3.1571 49.7959
CAL-39 GDSC1; GDSC2 -1.0628 6.4755 -2.5823 46.2826
OVCA420 GDSC1; GDSC2 -0.7431 7.0765 -2.4998 44.455
HEY GDSC1; GDSC2 -0.4498 3.7629 -0.9226 39.6214
SW756 GDSC1; GDSC2 0.9176 4.9874 0.1104 28.3044
OVCA433 GDSC1; GDSC2 0.9589 10.4414 -2.3581 36.6131
SW962 GDSC1; GDSC2 0.9803 8.0304 -1.1855 33.3044
JHOS-3 GDSC1; GDSC2 1.0164 7.8176 -1.0501 32.6933
OVMIU GDSC1; GDSC2 1.4356 8.9459 -1.1836 31.4454
ACC-OV7 GDSC1; GDSC2 1.6161 6.1985 0.2966 24.3736
SW954 GDSC1; GDSC2 1.9887 10.3868 -1.375 30.0431
NT2-D1 GDSC1; GDSC2 1.9931 7.4709 0.0574 24.1161
C-33 A GDSC1; GDSC2 2.0957 6.3239 0.7073 20.2975
PEO1 GDSC1; GDSC2 2.2245 8.3504 -0.1567 24.2983
SiSo GDSC1; GDSC2 2.459 11.6026 -1.5578 29.0581
SKN GDSC1; GDSC2 2.6064 8.2939 0.2171 21.1234
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 3.007 8.844 0.2942 19.4097
TC-YIK GDSC1; GDSC2 3.0748 11.1165 -0.7832 24.2241
DSH1 GDSC1; GDSC2 3.1304 6.3851 1.6279 11.2755
KGN GDSC1; GDSC2 3.2599 12.5141 -1.326 25.7635
OV17R GDSC1; GDSC2 3.2681 7.0159 1.4299 12.0851
HeLa GDSC1; GDSC2 3.3641 7.3943 1.3208 12.4693
HT-3 GDSC1; GDSC2 3.4824 11.116 -0.4422 21.5288
ME-180 GDSC1; GDSC2 3.7887 15.2097 -2.2376 27.2884
SKG-IIIa GDSC1; GDSC2 3.9215 9.8238 0.5561 15.3216
PA-1 GDSC1; GDSC2 3.9858 7.0984 1.9543 6.9014
NCC-IT GDSC2 4.1743 6.8199 2.2222 4.8385
C-4-I GDSC1; GDSC2 4.3058 16.8322 -2.6318 27.1083
NEC8 GDSC1; GDSC2 4.5899 7.2348 2.2941 3.6128
DoTc2 4510 GDSC1; GDSC2 4.6076 9.0664 1.4378 8.5899
JEG-3 GDSC1; GDSC2 4.631 8.4774 1.7366 6.7809
UWB1.289 GDSC1; GDSC2 4.7543 11.8953 0.1625 15.2411
LB831-BLC GDSC1; GDSC2 5.0598 13.0943 -0.2025 16.2761
PWR-1E GDSC1; GDSC2 5.0721 10.7282 0.9564 10.3174
JAR GDSC1; GDSC2 5.2393 6.7814 2.813 0.4441
HEC-1 GDSC1; GDSC2 5.3887 7.155 2.7346 0.5943
SiHa GDSC1; GDSC2 5.693 14.8122 -0.5871 16.5692
MS751 GDSC1; GDSC2 6.498 14.7263 -0.0004 12.2868
Ca Ski GDSC1; GDSC2 6.9103 19.1565 -1.841 18.9012
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7942).
2 RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer.Cancer Res.2009 Sep 1;69(17):6839-47.
3 Multicenter phase I trial of the mitogen-activated protein kinase 1/2 inhibitor BAY 86-9766 in patients with advanced cancer. Clin Cancer Res. 2013 Mar 1;19(5):1232-43.