Details of the Drug

General Information of Drug (ID: DMPWZOK)

Drug Name
CRB-0022
Synonyms Anti-NGF monoclonal antibody (osteoarthritis pain/chronic pain), Rottapharm Madaus; Anti-nerve growth factor monoclonal antibody (osteoarthritis pain/chronic pain), Rottapharm Madaus
Indication
Disease Entry ICD 11 Status REF
Pain MG30-MG3Z Investigative [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D0F2QP

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Low-affinity nerve growth factor receptor (NGFR) TTEDJN4 TNR16_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Pain
ICD Disease Classification MG30-MG3Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Low-affinity nerve growth factor receptor (NGFR) DTT NGFR 5.08E-01 0.38 0.37
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1888).