Details of the Drug

General Information of Drug (ID: DMQ0X7I)

Drug Name
IOX2
Synonyms compound 6
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 352.3
Logarithm of the Partition Coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C19H16N2O5
IUPAC Name
2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid
Canonical SMILES
C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O
InChI
InChI=1S/C19H16N2O5/c22-15(23)10-20-18(25)16-17(24)13-8-4-5-9-14(13)21(19(16)26)11-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23)
InChIKey
CAOSCCRYLYQBES-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
54685215
ChEBI ID
CHEBI:95087
CAS Number
931398-72-0
TTD ID
D0WA3E

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HIF-prolyl hydroxylase 2 (HPH-2) TT9ISBX EGLN1_HUMAN Inhibitor [1]
Lysine-specific demethylase 2A (KDM2A) TT8XTY2 KDM2A_HUMAN Inhibitor [1]
Lysine-specific demethylase 5C (KDM5C) TT94UCF KDM5C_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 -0.0761 3.4936 -4.5546 2.5626
ES6 GDSC1 -0.0578 7.7755 -6.4434 13.1507
CADO-ES1 GDSC1 -0.013 2.491 -4.1427 0.7597
SK-PN-DW GDSC1 0.0058 2.7152 -4.2174 1.0022
EW-18 GDSC1 0.1607 2.4651 -4.0677 0.4651
HuO9 GDSC1 0.1633 3.3487 -4.3909 1.5609
ES1 GDSC1 0.1722 3.7184 -4.5307 2.1754
NY GDSC1 0.1883 3.6937 -4.5137 2.0803
NOS-1 [Human HNSCC] GDSC1 0.1969 2.7006 -4.1375 0.6344
H-EMC-SS GDSC1 0.2149 20.9793 -12.6656 31.2944
SaOS-2 GDSC1 0.2226 2.4001 -4.0226 0.3415
ES8 GDSC1 0.2441 2.5774 -4.0763 0.4539
EW-3 GDSC1 0.2549 4.0272 -4.6157 2.4931
EW-22 GDSC1 0.2629 2.4958 -4.0412 0.3677
HOS GDSC1 0.2979 2.0791 -3.8885 0.1159
A-673 GDSC1 0.3009 1.9992 -3.8612 0.0886
MG-63 GDSC1 0.3412 3.0362 -4.2027 0.7537
SK-ES-1 GDSC1 0.382 2.0585 -3.8538 0.074
CAL-72 GDSC1 0.4126 3.3726 -4.2972 1.0185
SJSA-1 GDSC1 0.4369 5.4509 -5.1135 4.8597
CHSA8926 GDSC1 0.4658 3.2712 -4.2394 0.7996
EW-7 GDSC1 0.495 2.348 -3.911 0.1135
EW-12 GDSC2 0.5169 2.6177 -1.7559 1.7861
TC-71 GDSC1 0.5754 2.1351 -3.8154 0.0365
G-292 clone A141B1 GDSC1 0.5854 2.7724 -4.0216 0.243
EW-24 GDSC1 0.6191 2.1081 -3.7927 0.0252
HuO-3N1 GDSC1 0.6425 3.3757 -4.2096 0.6281
CAL-78 GDSC1 0.6619 2.7073 -3.9736 0.16
CHSA0108 GDSC1; GDSC2 0.7708 4.7798 -2.5812 5.6555
EW-13 GDSC1 0.8314 2.8493 -3.9635 0.124
ES4 GDSC1 0.8468 3.4586 -4.1635 0.4384
EW-11 GDSC1 0.8955 3.6266 -4.2042 0.5128
EW-1 GDSC1 0.9206 3.2892 -4.0796 0.2605
EW-16 GDSC1 0.9724 3.9887 -4.3032 0.7334
ES7 GDSC1 1.1726 3.5249 -4.072 0.1995
U-CH2 GDSC2 1.3971 3.5682 -1.7276 0.8399
CHSA0011 GDSC1; GDSC2 1.7374 3.9534 -1.7319 0.6267
U2OS GDSC1; GDSC2 1.9375 3.8588 -1.6212 0.2895
MHH-ES-1 GDSC1; GDSC2 1.9498 3.7181 -1.5681 0.1971
ES5 GDSC1; GDSC2 1.9543 4.8424 -1.9788 1.2784
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 163 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 1.0455 3.5142 -1.8663 1.6336
WSU-DLCL2 GDSC1 -9.0308 -7.6575 -9.0309 71.1645
K-562 GDSC1 -0.5313 1.936 -4.1461 1.1222
Daudi GDSC1 -0.468 2.6906 -4.4139 2.3032
SU-DHL-10 GDSC1 -0.4108 0.8386 -3.7178 0.0424
RC-K8 GDSC1 -0.3464 6.4226 -5.994 11.3443
JJN-3 GDSC1 -0.3062 2.0388 -4.0928 0.7677
MV4-11 GDSC1 -0.2922 2.9234 -4.4258 2.1636
JVM-2 GDSC1 -0.272 2.815 -4.3737 1.8906
TUR GDSC1 -0.2715 1.9124 -4.0337 0.5641
OCI-AML-2 GDSC1 -0.1837 1.6351 -3.905 0.2309
JURL-MK1 GDSC1 -0.1685 2.6779 -4.2755 1.358
AMO1 GDSC1 -0.1281 2.5456 -4.2087 1.0625
L-540 GDSC1 -0.1115 2.3836 -4.1422 0.8155
RPMI-8402 GDSC1 -0.1018 1.6566 -3.8838 0.1773
P32/ISH GDSC1 -0.1007 2.1455 -4.0522 0.5355
MOLP-8 GDSC1 -0.0952 2.1832 -4.0635 0.5644
KE-37 GDSC1 -0.0823 1.9246 -3.9681 0.3242
EB2 GDSC1 -0.0756 2.3249 -4.1068 0.6819
L-363 GDSC1 -0.0725 1.2679 -3.7463 0.037
BC-1 GDSC1 -0.0565 3.0701 -4.3782 1.7015
EM-2 GDSC1 -0.0498 1.6258 -3.8557 0.1296
MOLT-16 GDSC1 -0.0482 1.4356 -3.7927 0.066
SK-MM-2 GDSC1 -0.0359 2.2806 -4.0758 0.5709
IM-9 GDSC1 -0.0316 1.484 -3.803 0.0728
Jurkat GDSC1 -0.0162 1.8615 -3.9231 0.2209
P31/FUJ GDSC1 0.0017 1.4773 -3.7898 0.0593
SU-DHL-5 GDSC1 0.0048 1.2481 -3.7149 0.0198
NCI-H929 GDSC1 0.0196 2.1643 -4.0143 0.3914
JVM-3 GDSC1 0.0239 2.5772 -4.1596 0.793
KOPN-8 GDSC1 0.0261 1.8203 -3.8947 0.1677
BV-173 GDSC1 0.0539 2.1082 -3.9825 0.3116
OCI-AML-3 GDSC1 0.0871 3.1904 -4.3627 1.5075
TK [Human B-cell lymphoma] GDSC1 0.0906 2.7929 -4.2122 0.9286
MEG-01 GDSC1 0.0924 2.272 -4.0253 0.3905
VAL GDSC1 0.1125 2.2755 -4.0192 0.37
RPMI-6666 GDSC1 0.1172 2.2493 -4.0084 0.3454
GA-10 GDSC1 0.1181 1.8679 -3.8792 0.1316
MHH-CALL-2 GDSC1 0.1226 2.6128 -4.1343 0.6618
EJM GDSC1 0.1285 2.2871 -4.0174 0.3609
DEL GDSC1 0.1376 1.4581 -3.7394 0.0237
H9 GDSC1 0.139 2.4434 -4.0681 0.4747
MHH-PREB-1 GDSC1 0.1444 1.8819 -3.875 0.1226
697 GDSC1 0.1525 1.9071 -3.8806 0.1279
WIL2 NS GDSC1 0.1635 1.695 -3.8074 0.0585
ALL-SIL GDSC1 0.168 2.0881 -3.9357 0.1995
OCI-M1 GDSC1 0.1754 1.6029 -3.7737 0.0372
BL-41 GDSC1 0.1865 5.2179 -5.1441 5.4123
Karpas-299 GDSC1 0.1908 2.2231 -3.9734 0.2563
KMOE-2 GDSC1 0.1985 3.3289 -4.3684 1.4393
P12-Ichikawa GDSC1 0.209 1.6478 -3.7773 0.0372
MOLT-13 GDSC1 0.2131 3.1444 -4.293 1.1357
CESS GDSC1 0.2174 2.0272 -3.8985 0.1392
MLMA GDSC1 0.2228 2.7228 -4.1355 0.6167
HDLM-2 GDSC1 0.2237 2.6299 -4.1023 0.5267
PF-382 GDSC1 0.2265 2.1712 -3.9434 0.199
Namalwa GDSC1 0.2293 2.9063 -4.199 0.803
CCRF-CEM GDSC1 0.2301 2.1299 -3.9283 0.1762
Reh GDSC1 0.2312 2.0297 -3.8946 0.1324
CMK GDSC1 0.2361 2.0501 -3.8997 0.1378
CA46 GDSC1 0.2378 2.2839 -3.9775 0.2518
KY821 GDSC1 0.2503 1.7513 -3.7973 0.0456
EHEB GDSC1 0.2554 2.2508 -3.9602 0.2188
HAL-01 GDSC1 0.259 2.844 -4.1651 0.6839
Karpas-620 GDSC1 0.2625 1.889 -3.8379 0.0727
SUP-T1 GDSC1 0.2633 2.4253 -4.0167 0.3175
BALL-1 GDSC1 0.2647 2.1884 -3.936 0.1805
P30/OHK GDSC1 0.2658 2.2685 -3.9626 0.2202
Granta-519 GDSC1 0.2689 2.3908 -4.003 0.2895
Loucy GDSC1 0.2733 2.1688 -3.9266 0.1658
SUP-M2 GDSC1 0.2759 1.7489 -3.7882 0.039
NOMO-1 GDSC1 0.2761 2.1154 -3.9078 0.1412
Hs 445 GDSC1 0.3078 8.7518 -6.6685 13.5048
HH [Human lymphoma] GDSC1 0.3125 2.9275 -4.1746 0.685
HT GDSC1; GDSC2 0.315 1.9442 -1.5744 1.1263
L-428 GDSC1 0.3374 2.8094 -4.1233 0.5333
SR GDSC1 0.3563 2.2244 -3.9168 0.1395
MOLM-13 GDSC1 0.3597 2.4052 -3.9761 0.2209
ME1 GDSC1 0.3705 2.1356 -3.8828 0.1008
Sc-1 GDSC1 0.3705 2.1805 -3.8976 0.1158
LAMA-84 GDSC1 0.389 2.3805 -3.9577 0.1873
Jiyoye GDSC1 0.3917 2.9324 -4.1465 0.5703
CTV-1 GDSC1 0.3938 2.1245 -3.8714 0.0876
CML-T1 GDSC1 0.3947 1.9515 -3.8149 0.0465
SU-DHL-8 GDSC1 0.404 2.5385 -4.0057 0.2594
DG-75 GDSC1 0.4058 2.5222 -3.9996 0.2484
L-1236 GDSC1 0.4088 2.8575 -4.1138 0.4811
MOLT-4 GDSC1 0.4147 2.1578 -3.8754 0.0889
ARH-77 GDSC1 0.423 2.8536 -4.1073 0.4602
Ramos.2G6.4C10 GDSC1 0.4262 2.6214 -4.0261 0.2898
GR-ST GDSC1 0.4327 4.0335 -4.5387 1.9581
SUP-B8 GDSC1; GDSC2 0.4408 4.5748 -2.6974 6.9249
Karpas-231 GDSC1 0.4468 2.3735 -3.9357 0.148
SU-DHL-1 GDSC2 0.4561 4.0431 -2.4359 5.6123
LP-1 GDSC1; GDSC2 0.4621 2.3335 -1.6636 1.3633
SIG-M5 GDSC2 0.4622 1.5012 -1.3384 0.2107
A4/Fukuda GDSC1 0.4662 2.4921 -3.9686 0.1878
HC-1 GDSC1 0.4664 2.4595 -3.9576 0.1728
ALL-PO GDSC1 0.4706 3.1703 -4.2013 0.6846
SU-DHL-16 GDSC1; GDSC2 0.4819 1.8871 -1.4741 0.5824
RPMI-8226 GDSC1 0.4855 2.6916 -4.0291 0.2797
Karpas-1106P GDSC1 0.4957 2.4905 -3.958 0.1681
BE-13 GDSC1 0.5148 2.7979 -4.055 0.3195
RS4;11 GDSC1 0.5156 2.3226 -3.8958 0.0962
VL51 GDSC1 0.5172 2.4645 -3.942 0.1446
OPM-2 GDSC1 0.5183 2.0565 -3.8086 0.0362
ST486 GDSC1 0.5188 2.3884 -3.9163 0.1159
RPMI-8866 GDSC1 0.5236 2.2822 -3.88 0.0816
KCL-22 GDSC1 0.5281 5.8814 -5.2495 5.4686
TALL-1 [Human adult T-ALL] GDSC2 0.5357 7.6769 -4.1347 14.8694
YT GDSC1 0.5434 2.5069 -3.9473 0.1468
NALM-6 GDSC1 0.5478 2.7819 -4.0379 0.2794
KG-1 GDSC1 0.5513 2.3752 -3.9012 0.0971
MHH-CALL-4 GDSC2 0.5517 3.817 -2.271 4.4914
ATN-1 GDSC1 0.5733 2.4171 -3.9076 0.1006
LC4-1 GDSC1 0.5948 3.0457 -4.1116 0.4099
KM-H2 GDSC1 0.5991 2.3917 -3.8908 0.0831
NKM-1 GDSC1 0.6015 3.0097 -4.0968 0.3765
MN-60 GDSC1 0.6086 2.9651 -4.079 0.3388
U266B1 GDSC1 0.6161 2.5943 -3.9517 0.1409
GDM-1 GDSC1 0.6282 2.9475 -4.066 0.3089
Karpas-45 GDSC1 0.6362 2.3606 -3.8685 0.0631
HL-60 GDSC1 0.6403 2.2845 -3.8425 0.0468
OCI-AML-5 GDSC1 0.6414 1.9899 -3.7478 0.012
DB GDSC1 0.6457 2.3003 -3.8458 0.0483
DoHH2 GDSC2 0.6541 1.9448 -1.4245 0.3427
Farage GDSC1; GDSC2 0.6675 7.2827 -3.8473 12.7057
U-698-M GDSC1 0.6706 2.4443 -3.8843 0.0715
Ku812 GDSC1 0.6902 2.5276 -3.905 0.0858
Raji GDSC1 0.71 3.661 -4.2858 0.8119
Karpas-422 GDSC1 0.7234 2.6325 -3.9283 0.1028
EoL-1 GDSC1 0.7723 2.5689 -3.8914 0.0681
SU-DHL-6 GDSC1 0.8141 2.5197 -3.8619 0.047
MOLM-16 GDSC1; GDSC2 0.8187 2.5668 -1.5909 0.7464
ML-2 GDSC1 0.8202 2.6132 -3.8901 0.0635
WSU-NHL GDSC1 0.8209 2.7618 -3.9383 0.101
A3/Kawakami GDSC1 0.8336 2.0843 -3.7167 0.0048
SUP-HD1 GDSC1 0.8641 3.0035 -4.0034 0.1641
NB4 GDSC1; GDSC2 0.8691 2.0743 -1.3892 0.1731
QIMR-WIL GDSC1; GDSC2 0.8893 4.4046 -2.3375 4.1426
NK-92MI GDSC2 0.896 3.4989 -1.935 2.1849
DND-41 GDSC1 0.9051 3.0528 -4.0059 0.1607
NU-DUL-1 GDSC1; GDSC2 0.9809 2.6765 -1.564 0.553
HEL GDSC1; GDSC2 1.0434 2.3197 -1.4112 0.1645
MC116 GDSC1; GDSC2 1.0641 2.2471 -1.379 0.1116
Mono-Mac-6 GDSC1 1.0758 4.0369 -4.2816 0.6309
RCH-ACV GDSC1; GDSC2 1.1482 3.3902 -1.7676 1.1362
OCI-Ly19 GDSC1; GDSC2 1.1669 3.1387 -1.6613 0.7445
SKM-1 GDSC1; GDSC2 1.246 2.3538 -1.3524 0.0564
OCI-Ly7 GDSC1; GDSC2 1.2833 2.5205 -1.3952 0.0938
BC-3 GDSC2 1.2884 2.9506 -1.5425 0.3599
ROS-50 GDSC1; GDSC2 1.3364 3.6765 -1.796 1.0906
RL GDSC1; GDSC2 1.374 2.8645 -1.4804 0.1956
MY-M12 GDSC2 1.387 4.0727 -1.931 1.6268
JeKo-1 GDSC1; GDSC2 1.4239 3.4347 -1.6661 0.606
SU-DHL-4 GDSC1; GDSC2 1.4285 2.8266 -1.448 0.1341
CRO-AP2 GDSC1; GDSC2 1.475 3.3212 -1.6042 0.4171
THP-1 GDSC1; GDSC2 1.4944 3.4453 -1.6418 0.5032
KMS-11 GDSC1; GDSC2 1.5191 3.787 -1.7594 0.8352
Kasumi-1 GDSC1; GDSC2 1.5603 3.6308 -1.6838 0.584
PL-21 GDSC1; GDSC2 1.6737 3.7031 -1.6654 0.4817
BONNA-12 GDSC2 1.7032 4.0841 -1.7949 0.8623
CTB-1 GDSC1; GDSC2 2.1396 4.1299 -1.6419 0.27
⏷ Show the Full List of 163 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-GT-4 GDSC1 0.0793 4.0997 -4.7275 3.2677
FLO-1 GDSC1 0.1744 23.8135 -14.0974 33.4222
KYSE-220 GDSC1 0.1832 4.5982 -4.883 3.9631
OACP4 C GDSC1 0.2785 3.3331 -4.3368 1.2533
KYAE-1 GDSC1 0.3007 2.2331 -3.9387 0.1773
ESO-26 GDSC1 0.3037 2.1145 -3.8982 0.1258
HCE-4 GDSC1; GDSC2 0.3684 4.085 -2.5125 6.0194
ESO-51 GDSC1 0.3994 3.8827 -4.4948 1.7974
KYSE-50 GDSC1 0.7212 2.5926 -3.916 0.092
OACM5.1 C GDSC1 0.8536 3.4468 -4.157 0.4222
TE-12 GDSC1; GDSC2 2.6233 5.1345 -1.816 0.4554
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 0.3192 2.8328 -4.1384 0.5806
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-7 GDSC1 -1.6129 5.4019 -6.3546 16.5301
TGW GDSC1 -0.358 2.6597 -4.351 1.8713
SJNB-13 GDSC1 -0.1553 3.3255 -4.5238 2.4987
SK-N-AS GDSC1 -0.072 4.7376 -5.0741 5.4278
NB1 GDSC1 -0.011 2.0555 -3.9877 0.3427
GI-ME-N GDSC1 0.0141 2.8419 -4.2613 1.159
CHP-212 GDSC1 0.1135 5.9446 -5.5022 7.591
NB69 GDSC1 0.1817 14.877 -9.6925 25.1153
IMR-5 GDSC1 0.1825 2.0319 -3.9119 0.1624
NB(TU)1 GDSC1 0.2721 2.6637 -4.0963 0.4916
KP-N-YN GDSC1 0.309 7.1326 -5.9229 9.5943
GOTO GDSC1 0.3632 6.4399 -5.5816 7.5923
SJNB-10 GDSC1 0.3647 2.4403 -3.9862 0.236
SJNB-12 GDSC1 0.3931 2.5597 -4.0167 0.2815
NH-12 GDSC1 0.405 2.3324 -3.9362 0.1555
SK-N-FI GDSC1 0.4568 2.2134 -3.8796 0.0881
SJNB-14 GDSC1 0.5262 2.934 -4.0977 0.4026
SK-N-DZ GDSC1 0.5337 2.4519 -3.9323 0.131
SiMa GDSC1 0.5978 2.8959 -4.0592 0.3045
Kelly GDSC1 0.7023 2.5612 -3.912 0.0905
SK-N-BE(2)-M17 GDSC1 0.8055 2.6674 -3.9125 0.0809
MHH-NB-11 GDSC2 0.8207 2.8599 -1.7063 1.2252
SK-N-SH GDSC1 0.9422 10.9586 -7.2985 15.1231
SJNB-6 GDSC1; GDSC2 0.9622 4.6915 -2.4245 4.4875
SK-N-MC-IXC GDSC1; GDSC2 1.0332 2.2351 -1.3858 0.1273
CHP-126 GDSC1; GDSC2 1.0455 2.7052 -1.5484 0.4724
SJNB-17 GDSC2 1.1266 2.8257 -1.5604 0.481
KP-N-RT-BM-1 GDSC2 1.3569 3.5948 -1.7551 0.9636
SJNB-5 GDSC1; GDSC2 1.3864 3.2505 -1.6132 0.4792
LA-N-6 GDSC1; GDSC2 1.4812 2.9242 -1.4627 0.1438
KP-N-YS GDSC2 1.7627 3.705 -1.6319 0.3813
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 0.7524 2.7574 -3.9597 0.1304
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-415 GDSC1 -3.6854 1.7941 -6.1888 22.536
CAMA-1 GDSC1 -0.3976 3.8824 -4.8779 4.8092
BT-483 GDSC1 -0.3704 5.4939 -5.5806 8.9906
Hs 578T GDSC1 -0.1415 3.1618 -4.452 2.1281
HCC202 GDSC1 -0.0585 3.0128 -4.3569 1.6095
HCC1395 GDSC1 -0.0039 2.5019 -4.1431 0.7558
CAL-120 GDSC1 0.0011 1.9623 -3.9513 0.2663
HCC70 GDSC1 0.0201 2.5364 -4.1463 0.7526
OCUB-M GDSC1 0.0438 2.4149 -4.0935 0.5832
HCC38 GDSC1 0.0583 2.6653 -4.1782 0.8338
MFM-223 GDSC1 0.0983 1.9214 -3.9038 0.1668
Evsa-T GDSC1 0.1051 2.8367 -4.2225 0.9553
MDA-MB-157 GDSC1 0.1143 6.5871 -5.7903 9.2338
HCC1187 GDSC1 0.1252 1.8816 -3.8814 0.1331
AU565 GDSC1 0.1452 3.8979 -4.6144 2.6084
HCC1428 GDSC1 0.2348 5.4086 -5.2007 5.6557
HCC1419 GDSC1 0.271 4.6054 -4.8428 3.6292
HCC2157 GDSC1 0.2754 2.2144 -3.9411 0.1856
COLO 824 GDSC1 0.2963 2.8068 -4.1377 0.589
MDA-MB-453 GDSC1 0.3026 2.6486 -4.0798 0.4402
CAL-51 GDSC1 0.3046 8.0896 -6.3633 11.9627
HDQ-P1 GDSC1 0.3271 2.2693 -3.9417 0.1766
T-47D GDSC1 0.3292 2.4675 -4.0079 0.2823
HCC1806 GDSC1 0.3329 2.0209 -3.8577 0.0821
MDA-MB-231 GDSC1 0.3426 2.7641 -4.1055 0.4864
HCC1937 GDSC1 0.3565 2.6998 -4.078 0.4168
BT-474 GDSC1 0.4214 11.8173 -8.0449 19.2653
DU4475 GDSC1 0.4266 2.2988 -3.9178 0.13
BT-549 GDSC1 0.4306 3.1055 -4.1933 0.6811
HCC1143 GDSC1 0.4312 3.7243 -4.4208 1.4647
JIMT-1 GDSC1 0.4359 3.5405 -4.3499 1.1904
ZR-75-30 GDSC1 0.4623 4.0223 -4.5215 1.8563
BT-20 GDSC1 0.4672 2.3931 -3.9353 0.1443
MDA-MB-468 GDSC1 0.4682 2.2505 -3.888 0.0944
MRK-nu-1 GDSC1 0.4935 2.5372 -3.9743 0.1907
HCC1954 GDSC1 0.5035 2.9899 -4.1254 0.473
MDA-MB-175-VII GDSC1 0.5046 2.5635 -3.9793 0.1956
HCC1500 GDSC1 0.5719 2.5047 -3.9369 0.1307
EFM-192A GDSC1 0.5849 2.8508 -4.0484 0.2884
MDA-MB-436 GDSC1 0.7239 2.7377 -3.9627 0.1378
EFM-19 GDSC1 0.8246 2.9849 -4.0106 0.1797
MCF-7 GDSC1 0.9074 3.4388 -4.1351 0.3616
MDA-MB-361 GDSC1 0.9112 3.0114 -3.9901 0.1416
CAL-85-1 GDSC1 1.1572 3.4028 -4.0367 0.1586
YMB-1-E GDSC2 1.3097 3.1151 -1.5939 0.4815
MDA-MB-330 GDSC1; GDSC2 1.3211 3.4403 -1.711 0.8063
HCC1569 GDSC1; GDSC2 1.4905 4.0812 -1.8865 1.3043
HCC2218 GDSC1; GDSC2 1.5193 3.7137 -1.7315 0.7469
HCC1599 GDSC2 1.5312 3.588 -1.6796 0.6085
UACC-893 GDSC1; GDSC2 1.5916 3.5508 -1.6421 0.4598
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1783 GDSC1 -3.4472 -0.9025 -4.6376 10.8227
U-251MG GDSC1 -1.0037 3.9164 -5.24 8.2282
SF539 GDSC1 -0.5854 2.291 -4.3079 1.9031
Becker GDSC1 -0.4962 2.4383 -4.3258 1.895
D-392MG GDSC1 -0.1703 6.3189 -5.8378 10.078
SF268 GDSC1 -0.1199 2.5584 -4.2101 1.0621
MOG-G-UVW GDSC1 -0.0135 2.9948 -4.3307 1.4584
PFSK-1 GDSC1 0.0054 7.6506 -6.3453 12.4985
M059J GDSC1 0.084 4.1316 -4.7384 3.3191
KINGS-1 GDSC1 0.1354 6.6875 -5.8233 9.3785
YH-13 GDSC1 0.1662 2.2942 -4.0063 0.3257
SK-MG-1 GDSC1 0.1734 5.3049 -5.1885 5.6858
Daoy GDSC1 0.1881 2.0988 -3.9323 0.1903
CAS-1 GDSC1 0.1953 2.3803 -4.0256 0.3565
D-263MG GDSC1 0.2252 3.6465 -4.479 1.8873
ONS-76 GDSC1 0.2369 2.0085 -3.8857 0.1213
GB-1 GDSC1 0.2748 2.6023 -4.0738 0.4364
D283 Med GDSC1 0.2883 2.2178 -3.9378 0.1784
LN-229 GDSC1 0.3013 2.041 -3.8748 0.1014
8-MG-BA GDSC1 0.319 3.2544 -4.291 1.0571
GaMG GDSC1 0.3416 2.0495 -3.8642 0.0868
T98G GDSC1 0.3727 2.4606 -3.9903 0.2408
LN-405 GDSC1 0.4051 2.129 -3.8692 0.0845
DBTRG-05MG GDSC1 0.4103 7.5595 -6.0568 10.1268
LN-18 GDSC1 0.4122 9.4779 -6.9419 14.6028
U-118MG GDSC1 0.4762 2.3818 -3.9285 0.135
KS-1 [Human Krukenberg tumour] GDSC1 0.4818 3.4106 -4.2837 0.9313
H4 GDSC1 0.5257 3.1158 -4.1613 0.5522
MOG-G-CCM GDSC1 0.5409 2.7597 -4.0328 0.2722
U-87MG ATCC GDSC1 0.5416 2.4999 -3.9455 0.145
DK-MG GDSC1 0.5616 2.2391 -3.8535 0.0588
A-172 GDSC1 0.5678 15.4268 -9.6857 24.289
AM-38 GDSC1 0.6455 3.1754 -4.1382 0.4513
42-MG-BA GDSC1 0.6455 2.2677 -3.8354 0.0427
GI-1 GDSC1 0.7535 3.0539 -4.0582 0.264
SW1088 GDSC1 0.762 2.5896 -3.9015 0.0764
KNS-81-FD GDSC1; GDSC2 0.764 3.0496 -1.8123 1.6974
D-566MG GDSC1; GDSC2 0.8876 2.619 -1.5813 0.6658
LNZTA3WT4 GDSC1 0.9237 2.8602 -3.9364 0.0888
KNS-42 GDSC1; GDSC2 0.9536 2.4052 -1.4749 0.3243
Onda 11 GDSC1; GDSC2 0.9696 6.2249 -3.1324 8.2966
NMC-G1 GDSC1; GDSC2 0.9783 2.8761 -1.6413 0.8068
D-423MG GDSC1; GDSC2 1.0293 6.7031 -3.32 9.1855
Hs 683 GDSC1; GDSC2 1.0391 8.3296 -4.0941 13.1326
KALS-1 GDSC1 1.0748 3.455 -4.0821 0.2317
D-542MG GDSC1; GDSC2 1.1322 2.8603 -1.5709 0.4903
Onda 10 GDSC1; GDSC2 1.1565 3.3387 -1.7434 1.0388
SF295 GDSC1; GDSC2 1.1733 3.0571 -1.6276 0.6335
YKG-1 GDSC1; GDSC2 1.2842 2.5979 -1.4209 0.1256
D-336MG GDSC1; GDSC2 1.2889 4.0449 -1.9667 1.8162
D-247MG GDSC1; GDSC2 1.4441 3.8703 -1.8241 1.1097
D-502MG GDSC1; GDSC2 1.4943 3.2718 -1.5791 0.3511
SF126 GDSC1; GDSC2 1.5526 3.0446 -1.4785 0.1515
SNB-75 GDSC1; GDSC2 1.5529 3.4065 -1.6049 0.387
D-245MG GDSC2 1.9803 4.9506 -2.0096 1.4185
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 -0.0266 3.7541 -4.6369 2.9256
TGBC1TKB GDSC1 0.2266 2.1576 -3.9388 0.1921
TGBC24TKB GDSC1 0.5199 3.488 -4.297 0.9524
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EN GDSC1 -0.3782 2.5752 -4.3268 1.7776
KLE GDSC1 0.3023 4.1238 -4.6325 2.5229
MFE-319 GDSC1 0.3151 9.5099 -7.0191 15.1717
MFE-296 GDSC1 0.3638 3.1622 -4.2395 0.8561
AN3-CA GDSC1 0.5494 2.4359 -3.9218 0.1175
RL95-2 GDSC1 0.581 2.4606 -3.9193 0.111
MFE-280 GDSC1 0.7636 3.0859 -4.0655 0.2738
ESS-1 GDSC1 0.9152 15.8218 -9.634 23.4407
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
769-P GDSC1 -0.6871 2.0067 -4.2412 1.6875
A-704 GDSC1 -0.1818 1.9046 -3.9973 0.4269
SW13 GDSC1 0.0109 2.1164 -4.0008 0.3641
KTCTL-195 GDSC1 0.0903 8.3145 -6.6017 13.6377
BFTC-909 GDSC1 0.132 1.8953 -3.8836 0.1347
KMRC-1 GDSC1 0.1517 1.9535 -3.8963 0.1472
SN12C GDSC1 0.1821 2.5987 -4.1068 0.5565
LB996-RCC GDSC1 0.2007 3.2447 -4.3356 1.3067
CAL-54 GDSC1 0.2063 2.5839 -4.0925 0.5089
ACHN GDSC1 0.4812 2.5088 -3.969 0.1856
KMRC-20 GDSC1 0.5345 2.8289 -4.0586 0.3208
VMRC-RCZ GDSC1 0.622 3.3245 -4.1991 0.6093
BB65-RCC GDSC1; GDSC2 0.6681 5.6195 -3.044 8.4086
TK-10 GDSC1 0.723 8.1408 -6.1364 9.9543
A-498 GDSC1 0.7488 2.498 -3.8761 0.0597
786-O GDSC1 0.7576 2.758 -3.9581 0.1281
OS-RC-2 GDSC1 0.8378 2.8458 -3.9602 0.1198
KTCTL-140 GDSC1; GDSC2 1.2344 3.4779 -1.7634 1.051
NCC010 GDSC1; GDSC2 1.3392 3.9264 -1.8943 1.4662
KTCTL-13 GDSC1; GDSC2 1.3526 5.5393 -2.5795 4.6902
UO-31 GDSC1; GDSC2 1.3711 3.6605 -1.7744 0.9872
VMRC-RCW GDSC2 1.4444 3.1024 -1.5377 0.291
SW156 GDSC1; GDSC2 1.4555 3.4211 -1.6484 0.5398
KTCTL-26A GDSC1; GDSC2 1.4646 3.4422 -1.6525 0.5465
KTCTL-1M GDSC1; GDSC2 1.5529 3.785 -1.7445 0.7667
LB1047-RCC GDSC1; GDSC2 1.6079 4.1094 -1.8453 1.0631
KTCTL-21 GDSC1; GDSC2 1.6526 4.8362 -2.1161 2.0853
Caki-1 GDSC1; GDSC2 1.6871 3.4949 -1.5859 0.2986
NCC021 GDSC1; GDSC2 1.7127 3.4972 -1.5772 0.274
LB2241-RCC GDSC1; GDSC2 1.9004 3.9153 -1.6548 0.3682
RXF 393L GDSC1; GDSC2 1.9443 4.0923 -1.7014 0.4549
HA7-RCC GDSC1; GDSC2 1.9979 4.1579 -1.7044 0.4408
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RCM-1 [Human ESC] GDSC1 -0.4517 1.54 -3.9691 0.4677
SNU-1040 GDSC1 -0.2448 4.0383 -4.8645 4.487
CL-11 GDSC1 -0.1981 4.1822 -4.9016 4.6292
C2BBe1 GDSC1 -0.1596 3.2498 -4.4954 2.361
MDST8 GDSC1 -0.0902 3.0742 -4.3946 1.8069
HCT 116 GDSC1 -0.0732 1.726 -3.8972 0.1919
SW48 GDSC1 -0.0303 2.8277 -4.2743 1.2426
LoVo GDSC1 -0.0127 3.2749 -4.4388 1.9339
SW837 GDSC1 0.0257 2.3626 -4.0817 0.5588
HCC2998 GDSC1 0.0287 2.142 -4.0032 0.3634
RKO GDSC1 0.0823 3.5027 -4.486 2.0578
CW-2 GDSC1 0.0985 2.8481 -4.2293 0.9834
LS513 GDSC1 0.1269 1.8145 -3.8586 0.1071
GP5d GDSC1 0.1279 2.7798 -4.1927 0.8404
SNU-61 GDSC1 0.1582 2.5922 -4.1135 0.5854
SW1417 GDSC1 0.1951 2.5918 -4.0995 0.5316
T84 GDSC1 0.2121 3.2103 -4.318 1.2304
HT-55 GDSC1 0.2584 1.9955 -3.8742 0.1061
COLO 320HSR GDSC1 0.2622 2.1387 -3.9203 0.1594
SNU-407 GDSC1 0.2798 2.2257 -3.9433 0.188
SW1463 GDSC1 0.284 2.3104 -3.9704 0.2287
LS123 GDSC1 0.2855 2.1282 -3.9089 0.141
SNU-C5 GDSC1 0.3123 4.5168 -4.7864 3.2819
SK-CO-1 GDSC1 0.3394 4.6924 -4.8453 3.554
COLO205 GDSC1 0.3618 2.1231 -3.8816 0.1007
CCK-81 GDSC1 0.3944 2.7235 -4.0725 0.3918
HCT 15 GDSC1 0.4039 2.7807 -4.0889 0.4247
KM12 GDSC1 0.4078 3.7235 -4.4303 1.5213
COLO 678 GDSC1 0.446 2.3462 -3.9269 0.1377
LS1034 GDSC1 0.4503 3.1152 -4.1894 0.6605
SNU-C1 GDSC1 0.4609 5.3569 -5.0617 4.5433
CaR-1 GDSC1 0.5138 2.6241 -3.9965 0.2192
LS411N GDSC1 0.5219 2.1342 -3.8325 0.0486
DiFi GDSC1 0.5475 3.8528 -4.421 1.3768
SW948 GDSC1 0.5966 2.2166 -3.8348 0.0452
LS180 GDSC1 0.6059 2.6527 -3.9745 0.1705
NCI-H747 GDSC1 0.612 3.8434 -4.3911 1.2195
SW1116 GDSC1 0.691 2.8351 -4.0063 0.198
HT115 GDSC1; GDSC2 0.7587 2.3377 -1.5285 0.5777
NCI-H716 GDSC1 0.7864 2.8733 -3.9865 0.156
SW626 GDSC1 0.7973 2.8928 -3.9893 0.1576
SNU-283 GDSC2 0.9284 2.3756 -1.4739 0.3445
HT-29 GDSC1; GDSC2 0.9639 2.5274 -1.5154 0.4232
NCI-H508 GDSC1; GDSC2 1.0698 2.3727 -1.42 0.1725
SNU-C2B GDSC1 1.0782 3.5885 -4.1259 0.3
SNU-81 GDSC1; GDSC2 1.532 2.8971 -1.4359 0.1014
SW620 GDSC1; GDSC2 1.6847 3.4558 -1.573 0.2744
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 0.8563 3.2475 -4.0879 0.2893
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC1 -0.0793 3.6845 -4.6337 2.974
Hep 3B2.1-7 GDSC1; GDSC2 0.0008 2.2996 -1.909 3.2952
SK-HEP-1 GDSC1 0.0299 1.6911 -3.8505 0.1116
Hep-G2/C3A GDSC1 0.2027 2.3905 -4.0265 0.3559
HuH-1 GDSC1 0.2381 2.7849 -4.1519 0.6559
Huh-7 GDSC1 0.2626 2.4156 -4.0137 0.3117
HLE GDSC1 0.2902 2.9339 -4.1854 0.7283
SNU-423 GDSC1 0.304 2.3557 -3.9787 0.2378
SNU-398 GDSC1 0.3544 2.5745 -4.0355 0.3277
JHH-6 GDSC1 0.3953 1.7691 -3.7561 0.0204
SNU-449 GDSC1 0.4433 2.8106 -4.085 0.4025
JHH-2 GDSC1 0.5217 2.917 -4.0935 0.395
JHH-7 GDSC1 0.6334 2.3937 -3.8801 0.0716
JHH-4 GDSC1 0.6987 2.4412 -3.8741 0.0621
SNU-387 GDSC1 0.7225 17.3703 -10.5218 26.1214
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 182 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2795 GDSC1 -3.9229 4.6121 -7.8002 30.8196
NCI-H2461 GDSC1 -2.7108 3.4278 -6.202 19.0296
A-549 GDSC1 -1.7321 2.1163 -4.8578 7.3291
NCI-H1299 GDSC1 -1.5232 1.4323 -4.4202 3.9087
NCI-H1648 GDSC1 -0.754 2.7658 -4.5859 3.6449
NCI-H1869 GDSC1 -0.6663 2.234 -4.3223 2.066
RERF-LC-KJ GDSC1 -0.3436 2.8267 -4.4108 2.1462
COR-L23 GDSC1 -0.3308 2.7845 -4.3882 2.0213
LCLC-103H GDSC1 -0.329 3.268 -4.5832 3.0246
NCI-H2369 GDSC1 -0.2618 2.6792 -4.316 1.6153
PaCa-3 GDSC1 -0.236 2.7566 -4.3349 1.6756
NCI-H1304 GDSC1 -0.2182 2.445 -4.208 1.1259
NCI-H1792 GDSC1 -0.1898 4.4972 -5.033 5.383
SK-MES-1 GDSC1 -0.1855 2.5997 -4.2529 1.2789
NCI-H513 GDSC1 -0.1607 3.6239 -4.648 3.1542
NCI-H847 GDSC1 -0.1445 2.7955 -4.3102 1.484
NCI-H810 GDSC1 -0.1145 1.9293 -3.9814 0.364
NCI-H2731 GDSC1 -0.1017 21.3331 -13.0794 32.5117
NCI-H1793 GDSC1 -0.0813 5.3926 -5.3668 7.1602
HCC78 GDSC1 -0.0626 4.1364 -4.8127 3.9221
Calu-3 GDSC1 -0.0547 3.143 -4.4058 1.8238
NCI-H1975 GDSC1 -0.0498 2.5549 -4.1805 0.9081
IA-LM GDSC1 -0.0206 1.9725 -3.9625 0.2939
NCI-H1341 GDSC1 -0.0087 2.1895 -4.0334 0.4475
DMS 53 GDSC1 -0.0029 4.8661 -5.0928 5.4232
NCI-H1876 GDSC1 0.0255 3.0323 -4.3285 1.4169
NCI-H2170 GDSC1 0.0624 2.0035 -3.9438 0.2369
NCI-H1915 GDSC1 0.0759 2.1624 -3.9933 0.3268
NCI-H1581 GDSC1 0.0867 1.9992 -3.9339 0.2145
COLO 668 GDSC1 0.1007 3.2698 -4.3874 1.6
DMS 114 GDSC1 0.1048 8.2202 -6.5485 13.337
EPLC-272H GDSC1 0.1063 2.8826 -4.239 1.0125
Lu-139 GDSC1 0.1089 2.7909 -4.2042 0.8902
NCI-H2373 GDSC1 0.109 2.9316 -4.256 1.0722
NCI-H211 GDSC1 0.114 2.7039 -4.1704 0.7768
NCI-H596 GDSC1 0.1157 2.4329 -4.073 0.4965
NCI-H1092 GDSC1 0.138 3.0442 -4.2862 1.1637
NCI-H1781 GDSC1 0.1418 1.9479 -3.8977 0.1508
NCI-H2023 GDSC1 0.143 2.4912 -4.0834 0.5119
NCI-H526 GDSC1 0.1471 1.7718 -3.8378 0.0844
SW1271 GDSC1 0.179 4.2694 -4.7491 3.2546
VMRC-LCD GDSC1 0.1848 2.3922 -4.0335 0.3769
NCI-H2122 GDSC1 0.2084 4.8713 -4.985 4.4871
LCLC-97TM1 GDSC1 0.218 2.7036 -4.1305 0.605
NCI-H841 GDSC1 0.2252 7.2205 -6.0125 10.2505
NCI-H1650 GDSC1 0.2417 2.4149 -4.0209 0.3322
NCI-H2087 GDSC1 0.2447 18.6276 -11.4847 29.1403
NCI-H1568 GDSC1 0.2451 3.1712 -4.2899 1.1026
CPC-N GDSC1 0.2475 2.7261 -4.1274 0.583
NCI-H82 GDSC1 0.2511 2.0661 -3.9 0.1357
NCI-H1573 GDSC1 0.2626 2.469 -4.032 0.3485
NCI-H1355 GDSC1 0.2733 2.6242 -4.082 0.4563
NCI-H2595 GDSC1 0.2857 12.9332 -8.6747 21.8102
NCI-H1944 GDSC1 0.2937 13.4461 -8.9173 22.5859
NCI-H1694 GDSC1 0.2939 7.2938 -6.0049 10.0731
NCI-H2347 GDSC1 0.296 3.5264 -4.4025 1.4988
NCI-H1105 GDSC1; GDSC2 0.3079 2.8027 -1.9536 3.0204
NCI-H196 GDSC1 0.3092 2.0391 -3.8716 0.0973
NCI-H146 GDSC1; GDSC2 0.3109 2.2822 -1.7203 1.8132
EMC-BAC-2 GDSC1 0.3264 3.188 -4.2636 0.9576
LC-1/sq GDSC1 0.3276 8.0657 -6.3381 11.7842
Lu-135 GDSC1 0.3394 2.3875 -3.9772 0.2271
SBC-5 GDSC1 0.341 10.4137 -7.4295 16.9503
SBC-3 GDSC1 0.3414 2.6079 -4.0516 0.3646
Ms-1 GDSC1 0.351 2.1325 -3.8883 0.1087
NCI-H69 GDSC1 0.351 2.7853 -4.1098 0.4938
Lu-165 GDSC1 0.3558 2.1832 -3.9034 0.1241
NCI-H23 GDSC1 0.3691 11.2442 -7.8061 18.4488
NCI-H187 GDSC1 0.3734 1.9252 -3.8134 0.047
NCI-H1688 GDSC1 0.3755 2.1558 -3.8878 0.105
COR-L279 GDSC1 0.3761 2.1911 -3.8992 0.1167
LOU-NH91 GDSC1 0.3776 2.6521 -4.0539 0.3577
NCI-H441 GDSC1 0.3804 2.6009 -4.0353 0.3197
COR-L105 GDSC1 0.3838 3.043 -4.1888 0.6909
HOP-92 GDSC1 0.384 3.2906 -4.2784 0.9724
NCI-H727 GDSC1 0.3918 3.1353 -4.2189 0.7763
NCI-H2085 GDSC1 0.3992 3.9911 -4.5369 1.9813
Calu-6 GDSC1 0.4018 2.0494 -3.8443 0.0651
NCI-H1435 GDSC1 0.4148 2.2143 -3.8939 0.1063
HCC827 GDSC1 0.4281 2.4442 -3.9656 0.1909
NCI-H1623 GDSC1 0.4358 3.2276 -4.2352 0.8029
Lu-99A GDSC1 0.4386 2.8531 -4.1014 0.441
NCI-H2405 GDSC1 0.4582 2.8052 -4.0777 0.382
NCI-H1703 GDSC1 0.4608 2.2503 -3.8904 0.0974
NCI-H2722 GDSC1 0.4631 2.4149 -3.9439 0.1556
NCI-H209 GDSC1 0.4661 3.8835 -4.4666 1.6217
NCI-H2066 GDSC1 0.4669 12.3953 -8.2912 20.0814
SHP-77 GDSC1 0.4721 2.2425 -3.884 0.0904
NCI-H2818 GDSC1 0.4759 3.1495 -4.1919 0.6555
NCI-H2444 GDSC1; GDSC2 0.4905 1.887 -1.4703 0.5635
NCI-H520 GDSC1 0.5021 2.8641 -4.0823 0.3776
NCI-H522 GDSC1 0.5099 2.4492 -3.9395 0.1427
NCI-H1838 GDSC1 0.5103 2.6053 -3.9913 0.2122
HCC15 GDSC1 0.5116 2.4694 -3.9456 0.1497
COR-L95 GDSC1 0.5121 2.493 -3.9532 0.1592
BEN GDSC1; GDSC2 0.5167 2.285 -1.6167 1.1025
NCI-H1155 GDSC1 0.5172 2.3303 -3.8978 0.0979
NCI-H1693 GDSC1 0.5215 2.7895 -4.0498 0.3078
SK-LU-1 GDSC1 0.5343 2.8753 -4.0746 0.352
NCI-H524 GDSC1 0.5408 3.3699 -4.2461 0.7804
NCI-H1770 GDSC1; GDSC2 0.543 2.7686 -1.8069 1.9349
NCI-H1755 GDSC1 0.5441 7.376 -5.896 9.003
NCI-H446 GDSC1 0.5456 2.4655 -3.9328 0.1298
NCI-H2141 GDSC1 0.5504 2.4548 -3.9276 0.1236
LK-2 GDSC1 0.5535 2.6776 -4.0007 0.2174
NCI-H720 GDSC1 0.5584 2.0621 -3.7975 0.0294
KNS-62 GDSC1 0.5657 2.4677 -3.9268 0.1206
COR-L88 GDSC1 0.57 3.3176 -4.2162 0.6793
NCI-H1651 GDSC1 0.6254 2.6789 -3.9766 0.1698
NCI-H1993 GDSC1 0.6262 2.8385 -4.0298 0.2469
HCC366 GDSC1; GDSC2 0.6312 3.4346 -2.0507 3.0354
UMC-11 GDSC1 0.6352 2.481 -3.908 0.0941
HCC44 GDSC1 0.6376 2.6768 -3.9717 0.1616
NCI-H358 GDSC1 0.6379 2.8168 -4.0184 0.2264
NCI-H322M GDSC1 0.6573 4.8085 -4.7431 2.6706
DMS 273 GDSC1 0.6694 2.8863 -4.0309 0.239
NCI-H2009 GDSC1 0.6715 2.906 -4.0368 0.248
NCI-H2135 GDSC1; GDSC2 0.6724 2.8424 -1.7714 1.6151
EBC-1 GDSC1 0.6759 3.2737 -4.1614 0.4935
NCI-H661 GDSC1 0.6783 2.7296 -3.9755 0.1596
COR-L303 GDSC2 0.6788 3.5762 -2.0868 3.2642
NCI-H345 GDSC1; GDSC2 0.6863 1.8009 -1.3607 0.1738
NCI-H2591 GDSC1 0.6876 3.2044 -4.133 0.4254
NCI-H1563 GDSC1 0.6967 2.7566 -3.9782 0.1601
LXF 289 GDSC1 0.7002 2.7798 -3.9847 0.1676
HARA [Human squamous cell lung carcinoma] GDSC1 0.705 2.4766 -3.8835 0.068
Lu-65 GDSC1 0.714 2.7523 -3.9709 0.1486
NCI-H2228 GDSC1 0.7166 3.1716 -4.1114 0.3709
NCI-H835 GDSC1 0.7191 3.0314 -4.0626 0.2796
NCI-H226 GDSC1 0.723 25.2419 -14.3889 32.8801
HOP-62 GDSC1 0.7414 10.8363 -7.3689 15.8389
NCI-H1836 GDSC1; GDSC2 0.7993 2.3019 -1.4982 0.4606
NCI-H2342 GDSC1 0.8155 3.2147 -4.091 0.305
NCI-H650 GDSC1 0.846 22.6296 -13.0092 30.716
NCI-H1048 GDSC1 0.8545 2.4713 -3.8332 0.0315
COR-L321 GDSC1; GDSC2 0.871 2.6577 -1.6034 0.7521
NCI-H2227 GDSC1; GDSC2 0.8876 4.5776 -2.4169 4.5672
NCI-H2029 GDSC1; GDSC2 0.8935 2.7531 -1.6307 0.8317
NCI-H292 GDSC1; GDSC2 0.9024 2.8827 -1.6777 0.9984
IST-SL1 GDSC1; GDSC2 0.9083 3.4642 -1.914 1.997
NCI-H2171 GDSC2 0.9371 2.3074 -1.4461 0.2741
NCI-H1734 GDSC2 0.9697 2.8717 -1.6434 0.8497
SW1573 GDSC1 0.9851 14.1056 -8.7602 20.6257
NCI-H3255 GDSC1; GDSC2 1.0031 3.0407 -1.6948 0.9807
HCC33 GDSC2 1.0075 2.9547 -1.6591 0.8783
NCI-H1436 GDSC1; GDSC2 1.0316 2.8767 -1.6186 0.6935
NCI-H748 GDSC2 1.0558 3.2027 -1.7351 1.1285
COR-L32 GDSC1; GDSC2 1.0627 3.5126 -1.8572 1.5774
RERF-LC-MS GDSC1; GDSC2 1.0829 2.95 -1.6248 0.6806
NCI-H1666 GDSC1 1.0847 3.147 -3.9768 0.1067
NCI-H460 GDSC1; GDSC2 1.0915 2.3955 -1.42 0.167
NCI-H2172 GDSC1; GDSC2 1.1064 2.579 -1.4789 0.2743
NCI-H250 GDSC2 1.1184 3.0303 -1.6405 0.7336
NCI-H2804 GDSC1; GDSC2 1.1288 3.9311 -1.9988 2.1321
Lu-134-A GDSC1; GDSC2 1.1393 3.4085 -1.7789 1.1873
NCI-H838 GDSC1; GDSC2 1.1494 2.6943 -1.5037 0.313
NCI-H2196 GDSC2 1.1641 2.8456 -1.5528 0.4413
IST-SL2 GDSC1; GDSC2 1.1828 3.8337 -1.9313 1.7726
LB647-SCLC GDSC1; GDSC2 1.1961 2.9289 -1.5706 0.4578
NCI-H2810 GDSC1; GDSC2 1.2352 8.8759 -4.2221 13.3371
CAL-12T GDSC1; GDSC2 1.2373 3.1678 -1.6428 0.6421
RERF-LC-Sq1 GDSC1 1.2407 3.5649 -4.0622 0.1757
NCI-H290 GDSC1; GDSC2 1.2836 2.9712 -1.5518 0.3712
NCI-H510A GDSC2 1.3237 3.3396 -1.6717 0.7037
NCI-H2081 GDSC1; GDSC2 1.3536 3.2861 -1.6394 0.5674
NCI-H740 GDSC2 1.4391 4.2505 -1.9786 1.7784
ChaGo-K-1 GDSC1; GDSC2 1.446 3.3628 -1.6307 0.4971
ABC-1 GDSC1; GDSC2 1.4721 3.721 -1.7542 0.8485
SBC-1 GDSC1; GDSC2 1.5286 11.2497 -5.1669 16.9024
LC-2/ad GDSC1; GDSC2 1.5503 4.1832 -1.8999 1.3054
DMS 79 GDSC1; GDSC2 1.5629 3.5686 -1.6598 0.5182
NCI-H1437 GDSC1; GDSC2 1.6016 3.4412 -1.5988 0.3548
NCI-H2803 GDSC1; GDSC2 1.6449 3.5739 -1.6299 0.4082
PC-14 GDSC1; GDSC2 1.6816 3.3885 -1.5507 0.2348
NCI-H2030 GDSC1; GDSC2 1.7736 3.4493 -1.5386 0.1921
NCI-H2869 GDSC1; GDSC2 1.7812 4.5145 -1.927 1.2238
NCI-H2110 GDSC1; GDSC2 1.792 4.1074 -1.767 0.6973
NCI-H2291 GDSC1; GDSC2 1.8857 3.8183 -1.626 0.3145
NCI-H647 GDSC2 1.9371 3.8799 -1.6287 0.3146
A-427 GDSC1; GDSC2 2.0616 16.0503 -7.1277 22.5778
EKVX GDSC1; GDSC2 2.2518 4.3619 -1.6818 0.3097
EMC-BAC-1 GDSC1; GDSC2 2.384 4.9222 -1.8311 0.5824
⏷ Show the Full List of 182 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 0.7007 3.2395 -4.1405 0.4372
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-4 GDSC1 -3.3437 1.9036 -5.9529 19.7899
T.T GDSC1 -0.2281 5.9103 -5.6855 9.3173
KYSE-70 GDSC1 -0.1604 3.913 -4.7681 3.8127
TE-5 GDSC1 -0.077 4.4841 -4.9675 4.8197
KYSE-150 GDSC1 -0.0181 1.688 -3.8657 0.1368
TE-8 GDSC1 0.0361 4.2633 -4.8165 3.8038
TE-6 GDSC1 0.0743 2.3175 -4.0477 0.4501
TE-1 GDSC1 0.1706 3.8321 -4.5765 2.3949
KYSE-410 GDSC1 0.3063 3.7338 -4.4776 1.8062
KYSE-140 GDSC1 0.3615 5.9966 -5.3878 6.5046
KYSE-450 GDSC1 0.3681 2.5266 -4.0143 0.2836
TE-9 GDSC1 0.3968 2.5874 -4.0249 0.2954
OE21 GDSC1 0.4473 2.7191 -4.052 0.333
COLO 680N GDSC1 0.4682 2.5835 -3.9986 0.2325
KYSE-270 GDSC1 0.4896 2.8752 -4.0906 0.3993
EC-GI-10 GDSC1 0.5885 2.6397 -3.976 0.1756
OE19 GDSC1 0.6979 2.6988 -3.9586 0.1369
OE33 GDSC1 0.7024 2.8345 -4.0022 0.1902
KYSE-180 GDSC1 0.7046 3.0748 -4.0825 0.3186
KYSE-520 GDSC1 0.8384 3.0383 -4.0238 0.1947
TE-15 GDSC1 0.8909 3.2007 -4.0601 0.2366
KYSE-510 GDSC1; GDSC2 1.1591 2.587 -1.4621 0.2231
TE-11 GDSC1; GDSC2 1.261 3.3501 -1.7022 0.817
TE-10 GDSC1; GDSC2 1.3355 3.9855 -1.92 1.5737
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TOV-112D GDSC1 -3.9277 -2.5215 -4.2953 10.195
TYK-nu GDSC1 -3.78 -2.7815 -4.0291 7.4932
OC 314 GDSC1 -0.9135 1.8744 -4.2931 2.2102
EFO-21 GDSC1 -0.0743 3.8411 -4.6956 3.297
OVCAR-4 GDSC1 -0.004 3.5589 -4.5474 2.4446
OAW28 GDSC1 0.0054 3.3038 -4.4421 1.9312
DOV13 GDSC1 0.1048 12.124 -8.4092 21.2972
OV56 GDSC1 0.1519 1.9489 -3.8947 0.1452
OVCAR-3 GDSC1 0.1644 2.0456 -3.9227 0.1809
ES-2 GDSC1 0.2106 2.0468 -3.9072 0.1513
OVKATE GDSC1 0.3224 25.9229 -15.0293 34.3003
RMG-I GDSC1 0.3594 2.6505 -4.0598 0.3761
A2780 GDSC1 0.3682 2.7006 -4.074 0.4039
OVISE GDSC1 0.3714 2.3412 -3.9506 0.1806
OVCAR-8 GDSC1 0.3754 6.038 -5.3983 6.5404
OVCAR-5 GDSC1 0.3794 2.7061 -4.0719 0.3954
OAW42 GDSC1 0.3812 1.7589 -3.7574 0.0213
OVTOKO GDSC1 0.4958 9.7449 -7.0137 14.7616
Kuramochi GDSC1 0.5074 15.6689 -9.8461 24.8493
OVK18 GDSC1; GDSC2 0.5147 3.0085 -1.9271 2.5694
FU-OV-1 GDSC1 0.5688 4.2479 -4.5626 1.9379
Caov-4 GDSC1 0.5875 3.7664 -4.3725 1.169
SK-OV-3 GDSC1 0.7527 2.4749 -3.8674 0.054
TOV-21G GDSC1 0.7637 3.0478 -4.0526 0.2526
IGROV-1 GDSC1 0.7951 3.3388 -4.1408 0.4068
OV-90 GDSC1 0.8248 2.9606 -4.0025 0.1693
Caov-3 GDSC2 0.9507 2.4977 -1.5097 0.4292
JHOS-4 GDSC2 1.2167 3.1146 -1.6313 0.6416
EFO-27 GDSC1; GDSC2 1.4156 3.9452 -1.8665 1.2905
JHOS-2 GDSC1; GDSC2 1.4621 3.0455 -1.5112 0.2255
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuP-T3 GDSC1 -2.0683 5.2561 -6.6163 19.2615
SU.86.86 GDSC1 -0.4902 7.9293 -6.7985 15.9452
Capan-1 GDSC1 -0.3677 3.6881 -4.7788 4.1804
PaTu 8902 GDSC1 -0.1841 2.2991 -4.1399 0.8524
DAN-G GDSC1 0.0576 1.9799 -3.9375 0.2273
SUIT-2 GDSC1 0.0744 1.9024 -3.9056 0.174
Hs 766T GDSC1 0.0876 3.0839 -4.322 1.3406
PSN1 GDSC1 0.1441 1.9223 -3.8884 0.1387
KP-1N GDSC1 0.1483 3.1885 -4.3362 1.3497
KP-2 GDSC1 0.1553 1.8441 -3.8588 0.1036
Capan-2 GDSC1 0.1664 3.8403 -4.5816 2.4246
KP-4 GDSC1 0.2223 1.9975 -3.887 0.1249
Panc 03.27 GDSC1 0.3136 1.9894 -3.8538 0.0808
Panc 08.13 GDSC1 0.3183 2.6249 -4.0658 0.4028
Panc 02.03 GDSC1 0.3339 2.4747 -4.0087 0.2825
HuP-T4 GDSC1 0.3434 14.3444 -9.3182 23.7092
HPAC GDSC1 0.3503 2.2827 -3.9383 0.1676
CFPAC-1 GDSC1 0.3542 2.6052 -4.0461 0.3491
PaTu 8988t GDSC1 0.473 3.2426 -4.2263 0.7563
Panc 10.05 GDSC1 0.497 2.7052 -4.0297 0.2778
Panc 04.03 GDSC1 0.5021 2.5966 -3.9913 0.2138
YAPC GDSC1 0.516 2.1756 -3.8478 0.0585
QGP-1 GDSC1; GDSC2 0.5416 2.6758 -1.7678 1.7508
PL4 GDSC1 0.6265 2.6345 -3.9615 0.1509
AsPC-1 GDSC1 0.7021 3.1041 -4.0934 0.3399
KP-3 GDSC1 0.7458 11.9686 -7.9009 18.0193
HPAF-II GDSC1 0.793 3.1983 -4.0934 0.315
BxPC-3 GDSC1 0.8164 3.1068 -4.0543 0.2435
SW1990 GDSC1 0.9874 3 -3.961 0.1032
MZ-PC-1 GDSC1; GDSC2 1.5232 3.5644 -1.6742 0.5764
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1 -0.6222 7.3089 -6.5907 15.2157
NCI-H28 GDSC1 0.009 4.9218 -5.1105 5.5064
IST-Mes1 GDSC1 0.4347 19.8358 -11.9387 29.6383
NCI-H2452 GDSC1 0.557 3.3877 -4.2463 0.7726
MPP 89 GDSC1 0.6319 3.0261 -4.0916 0.3567
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1 -2.9916 4.836 -7.129 24.748
22Rv1 GDSC1 -0.0165 3.8729 -4.6807 3.1424
DU145 GDSC1 0.3019 2.9203 -4.1761 0.6945
VCaP GDSC1 0.3853 2.6724 -4.0581 0.3641
PC-3 GDSC1 0.4332 2.5809 -4.0099 0.2593
NCI-H660 GDSC2 0.9674 2.4589 -1.489 0.3655
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 0.3538 2.5977 -4.0437 0.3443
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-31 GDSC1; GDSC2 -0.9119 0.6303 -1.743 4.3003
WM793 GDSC1 -0.4528 2.8308 -4.4635 2.543
GAK GDSC1 -0.2942 2.5686 -4.2873 1.5177
Mel JuSo GDSC1 -0.142 1.7314 -3.9231 0.2527
WM35 GDSC1 -0.0171 2.6063 -4.1864 0.9077
UACC-62 GDSC1 0.0367 1.8436 -3.8988 0.1716
COLO 679 GDSC1 0.0819 2.1884 -4.0001 0.3392
SK-MEL-2 GDSC1 0.1673 8.0585 -6.4338 12.6151
IST-MEL1 GDSC1 0.1823 6.9507 -5.9151 9.799
SK-MEL-24 GDSC1 0.2356 2.3203 -3.9907 0.2758
CHL-1 GDSC1 0.2411 2.1903 -3.9448 0.198
WM115 GDSC1 0.2484 2.781 -4.1466 0.6358
IPC-298 GDSC1; GDSC2 0.2588 3.3391 -2.2316 4.6381
RPMI-7951 GDSC1 0.2761 16.0249 -10.1853 26.2019
WM1552C GDSC1 0.298 8.4215 -6.521 12.7863
COLO 792 GDSC1 0.308 3.7723 -4.4917 1.8665
LOX-IMVI GDSC1 0.314 2.8941 -4.1621 0.6484
A2058 GDSC1 0.3158 15.5214 -9.9109 25.4174
HMV-II GDSC1 0.3702 5.7068 -5.2575 5.7588
SK-MEL-1 GDSC1 0.3769 2.1341 -3.8802 0.0975
UACC-257 GDSC1 0.3785 2.2384 -3.914 0.1328
IGR-37 GDSC1 0.4103 3.2804 -4.2643 0.9097
SH-4 GDSC1 0.4131 2.5008 -3.9898 0.2307
M14 GDSC1 0.4544 3.1924 -4.2154 0.7333
G-361 GDSC1 0.463 2.1228 -3.848 0.0627
IGR-1 GDSC1 0.5648 18.4935 -11.1845 27.91
MeWo GDSC1 0.5869 2.2395 -3.8453 0.0519
HT-144 GDSC1 0.637 5.6049 -5.0774 4.3822
A101D GDSC1 0.6734 9.287 -6.6895 12.8542
MZ-MEL-7 GDSC1; GDSC2 0.7599 2.6103 -1.6343 0.9515
WM278 GDSC1 0.7719 4.402 -4.535 1.6506
MMAc-SF GDSC1; GDSC2 0.81 2.466 -1.5558 0.6332
SK-MEL-3 GDSC1; GDSC2 0.8351 2.6476 -1.6152 0.8204
CP66-MEL GDSC1; GDSC2 0.8585 2.3361 -1.487 0.3985
Hs 940.T GDSC1; GDSC2 0.9248 3.7826 -2.0417 2.5835
RVH-421 GDSC1; GDSC2 0.9617 2.7017 -1.5815 0.6188
VMRC-MELG GDSC1; GDSC2 1.0112 2.2284 -1.3913 0.1404
COLO 829 GDSC1 1.0193 13.5937 -8.4928 19.645
Hs 938.T GDSC1; GDSC2 1.0439 3.0098 -1.6646 0.8406
SK-MEL-30 GDSC1; GDSC2 1.0971 2.4173 -1.4256 0.1748
COLO 783 GDSC1; GDSC2 1.1074 2.4276 -1.4254 0.1719
LB373-MEL-D GDSC1; GDSC2 1.1525 2.7152 -1.51 0.3262
DJM-1 GDSC2 1.1845 3.3647 -1.7412 1.0448
A-375 GDSC1; GDSC2 1.2279 2.6691 -1.4655 0.2092
Mel Ho GDSC1; GDSC2 1.2767 2.986 -1.5598 0.3934
451Lu GDSC1; GDSC2 1.2817 3.394 -1.7101 0.8296
A-431 GDSC1; GDSC2 1.3058 3.342 -1.68 0.7163
SK-MEL-5 GDSC1; GDSC2 1.3827 3.1573 -1.5807 0.3992
WT2-iPS GDSC1; GDSC2 1.4072 2.7899 -1.443 0.1315
G-mel GDSC1; GDSC2 1.4246 2.9986 -1.5086 0.2313
CP50-MEL-B GDSC1; GDSC2 1.453 3.1153 -1.539 0.2809
LB2518-MEL GDSC1; GDSC2 1.4566 3.1894 -1.564 0.3318
COLO 800 GDSC1; GDSC2 1.5765 3.1568 -1.5085 0.1912
A-388 GDSC1; GDSC2 1.6571 3.7154 -1.6764 0.5171
SK-MEL-28 GDSC1; GDSC2 1.7319 13.024 -5.8862 19.2367
MZ-MEL-2 GDSC1; GDSC2 1.7962 3.5969 -1.5814 0.2576
EquiPSC Line K2 GDSC1; GDSC2 1.8785 4.7343 -1.97 1.3044
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 1.3886 7.2952 -3.366 8.7422
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-LMS-1 GDSC1 -0.5564 3.2309 -4.6817 3.9042
RD GDSC1 -0.3319 2.8092 -4.3985 2.0727
MES-SA GDSC1 -0.3302 3.0343 -4.4882 2.5225
VA-ES-BJ GDSC1 -0.163 4.7765 -5.1402 5.9693
SW684 GDSC1 -0.0269 3.518 -4.5416 2.4416
SK-UT-1 GDSC1 0.024 2.436 -4.1086 0.6357
KYM-1 GDSC1 0.0302 1.8112 -3.8902 0.1608
SW982 GDSC1 0.0819 2.4659 -4.0973 0.5759
RKN GDSC1 0.0932 6.4054 -5.7204 8.8791
Hs 633.T GDSC1 0.0964 1.6317 -3.8089 0.0653
GCT GDSC1 0.1054 5.7333 -5.413 7.0913
EW-8 GDSC1 0.1667 3.0215 -4.2661 1.0695
Rh18 GDSC1 0.2297 2.038 -3.8979 0.1365
SW872 GDSC1 0.3606 2.1582 -3.8936 0.1129
Rh30 GDSC1 0.3715 2.7234 -4.0807 0.4178
A-204 GDSC1 0.3857 3.4162 -4.3241 1.1307
HT-1080 GDSC1 0.4419 1.8279 -3.76 0.0202
MFH-ino GDSC1 0.4842 3.4911 -4.3123 1.0255
G-401 GDSC1 0.4856 2.7233 -4.0399 0.2991
G-402 GDSC1 0.6401 2.9714 -4.07 0.313
Rh41 GDSC1 0.6913 2.7575 -3.9803 0.1635
TE 441.T GDSC2 1.1966 2.689 -1.4841 0.2634
STS-0421 GDSC1; GDSC2 2.2436 4.7175 -1.8115 0.5951
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS GDSC1 -2.9449 4.9383 -7.1422 24.6467
HSC-39 GDSC1 -0.9339 2.8682 -4.7264 4.8003
NCI-N87 GDSC1 -0.3418 4.158 -4.9674 5.2491
HGC-27 GDSC1 -0.0228 1.9148 -3.9436 0.2585
SNU-16 GDSC1 -0.019 1.9048 -3.9388 0.2489
KATO III GDSC1 -0.017 2.1342 -4.0172 0.4114
SNU-1 GDSC1 0.0524 2.3673 -4.0734 0.5245
SNU-5 GDSC1 0.0582 2.3827 -4.0767 0.5307
ECC12 GDSC2 0.1012 3.8543 -2.582 7.2049
IM95 GDSC1 0.1158 2.0971 -3.9569 0.2463
RF-48 GDSC1 0.1435 2.3022 -4.0173 0.3556
NUGC-4 GDSC1 0.1525 21.7256 -13.0812 32.0522
ECC10 GDSC1 0.1982 2.4973 -4.0652 0.4446
NUGC-3 GDSC1 0.2581 2.3378 -3.9887 0.2663
SK-GT-2 GDSC1 0.2786 2.994 -4.2117 0.8154
MKN28 GDSC1 0.3196 4.3958 -4.7337 3.0038
MKN1 GDSC1 0.3327 2.5895 -4.0484 0.3605
MKN45 GDSC1 0.3503 2.5418 -4.0258 0.3099
TGBC11TKB GDSC1 0.4081 2.2085 -3.8942 0.1074
23132/87 GDSC1 0.5224 2.505 -3.9537 0.1581
Fu97 GDSC1 0.697 2.7263 -3.968 0.1478
Hs 746.T GDSC1 0.7424 2.4738 -3.8704 0.0565
RERF-GC-1B GDSC1 0.8758 3.5438 -4.1826 0.4704
SCH GDSC1; GDSC2 0.9944 2.5707 -1.5192 0.4183
TMK-1 GDSC1; GDSC2 1.2934 3.3416 -1.6851 0.7401
MKN7 GDSC1; GDSC2 1.6299 3.472 -1.5991 0.3453
SNG-M GDSC1 0.3866 2.4901 -3.9954 0.2461
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CGTH-W-1 GDSC1 -2.8962 2.0705 -5.6721 16.3783
BHT-101 GDSC1 -0.6 4.6064 -5.313 7.8375
8305C GDSC1 -0.1081 2.2071 -4.077 0.6091
TT GDSC1 0.0444 2.4523 -4.1066 0.62
CAL-62 GDSC1 0.1351 11.6353 -8.1524 20.2998
WRO GDSC1 0.1794 5.4214 -5.2358 5.9458
K5 GDSC1 0.2022 3.6911 -4.5066 2.0337
IHH-4 GDSC1 0.3021 6.8483 -5.7986 8.9194
8505C GDSC1 0.4149 11.0112 -7.6645 17.7764
TT2609-C02 GDSC1 0.4172 2.9535 -4.1444 0.5542
ASH-3 GDSC1 0.47 10.3848 -7.3314 16.2468
B-CPAP GDSC1 0.5776 2.15 -3.8195 0.0384
KMH-2 GDSC1; GDSC2 0.6228 2.4946 -1.6516 1.1452
ML-1 [Human leukemia] GDSC1; GDSC2 0.7212 2.5003 -1.6082 0.8845
FTC-133 GDSC1 0.8169 2.3091 -3.7935 0.0191
HTC-C3 GDSC1 0.99 3.4099 -4.0963 0.2716
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-27 GDSC1 -3.7857 -2.8431 -4.0078 7.3629
HSC-4 GDSC1 -3.6146 -1.8853 -4.2967 8.8167
UPCI-SCC-090 GDSC1 -3.0218 7.1792 -8.3245 29.4015
CAL-33 GDSC1 -0.7793 13.1532 -9.5484 26.8671
HSC-2 GDSC1 -0.6388 4.4888 -5.2826 7.728
PCI-38 GDSC1 -0.3577 4.0303 -4.9206 4.997
SCC-9 GDSC1 -0.1952 8.6225 -6.9325 15.902
HSC-3 GDSC1 -0.1809 1.318 -3.7982 0.0849
BICR 22 GDSC1 -0.046 2.0589 -4.0015 0.3854
HO-1-N-1 GDSC1 0.0366 2.4012 -4.0914 0.5805
SAS GDSC1 0.1043 2.5089 -4.1041 0.5845
HO-1-u-1 GDSC1 0.1835 2.069 -3.9239 0.179
DOK GDSC1 0.2217 4.6772 -4.8968 3.9851
FaDu GDSC1 0.3249 3.0088 -4.199 0.7512
BB49-HNC GDSC1 0.3314 3.7184 -4.4608 1.7119
Detroit 562 GDSC1 0.3327 2.2626 -3.9375 0.1698
BICR 78 GDSC1 0.3511 2.2376 -3.923 0.1478
NCI-H3118 GDSC1 0.36 3.3998 -4.3284 1.1641
LB771-HNC GDSC1 0.3899 6.8419 -5.7453 8.4589
OSC-20 GDSC1 0.394 3.3295 -4.2887 1.0012
BICR 10 GDSC1 0.4684 3.2254 -4.2219 0.7455
SKN-3 GDSC1 0.4822 2.7282 -4.0428 0.3054
SCC-15 GDSC1 0.4866 2.9084 -4.1032 0.428
SCC-4 GDSC1 0.4877 4.8631 -4.844 3.3614
JHU-022 GDSC1 0.5265 3.3158 -4.2321 0.7463
Ca9-22 GDSC1 0.5789 2.7082 -4.0023 0.2144
PCI-30 GDSC1 0.6406 5.3246 -4.9595 3.7626
PCI-15A GDSC1; GDSC2 0.9466 2.624 -1.5584 0.556
KON GDSC1; GDSC2 1.0031 3.1165 -1.7248 1.0943
KOSC-2 GDSC1; GDSC2 1.0205 3.4764 -1.8628 1.6445
JHU-011 GDSC1; GDSC2 1.1793 3.3682 -1.7449 1.0262
BICR 31 GDSC2 1.271 2.7541 -1.4795 0.2303
OSC-19 GDSC1; GDSC2 1.2877 3.2097 -1.6377 0.5983
BHY GDSC1; GDSC2 1.3162 3.3505 -1.6789 0.7065
JHU-029 GDSC1; GDSC2 1.444 4.0411 -1.8918 1.3637
PCI-04B GDSC1; GDSC2 1.5525 4.3086 -1.9489 1.4923
SCC-25 GDSC1; GDSC2 1.667 3.664 -1.6538 0.4561
PE/CA-PJ15 GDSC1; GDSC2 1.7124 3.5222 -1.5861 0.291
BB30-HNC GDSC2 1.8819 3.3865 -1.4797 0.1014
PCI-06A GDSC1; GDSC2 2.0983 4.0293 -1.622 0.2471
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC1 -0.2349 2.0706 -4.0765 0.6739
BFTC-905 GDSC1 -0.2031 2.4355 -4.1982 1.0769
RT-4 GDSC1 -0.1353 3.2463 -4.4828 2.2716
TCCSUP GDSC1 0.0087 2.3696 -4.0907 0.5917
CAL-29 GDSC1 0.098 2.4038 -4.0693 0.4944
SW1710 GDSC1 0.1952 2.8303 -4.1847 0.7768
639V GDSC1 0.2191 1.4817 -3.7208 0.0151
SW780 GDSC1 0.2575 2.5468 -4.0608 0.4126
RT-112 GDSC1 0.2594 1.5536 -3.7309 0.0168
HT-1197 GDSC1 0.3615 2.383 -3.968 0.208
647V GDSC1 0.3697 2.0741 -3.8629 0.0828
5637 GDSC1 0.4185 10.0287 -7.1967 15.7606
UM-UC-3 GDSC1 0.5015 2.4324 -3.9367 0.1407
HT-1376 GDSC1 0.555 2.5939 -3.9722 0.1764
J82 GDSC1 0.7835 2.7113 -3.9342 0.1014
T24 GDSC1; GDSC2 1.9445 4.0159 -1.674 0.3934
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB831-BLC GDSC1 -3.7112 3.5175 -7.0712 27.1302
C-33 A GDSC1 -2.6959 0.0826 -4.5348 7.5058
HEY GDSC1 -0.6206 11.3948 -8.5685 23.5274
PWR-1E GDSC1 -0.6038 2.381 -4.3524 2.1473
OVMIU GDSC1 -0.5668 6.441 -6.1426 12.678
HEC-1 GDSC1 -0.1476 1.8376 -3.9616 0.3316
KGN GDSC1 0.0352 9.0455 -6.9815 15.6108
CAL-39 GDSC1 0.0519 2.0471 -3.9623 0.2729
HeLa GDSC1 0.1048 1.7796 -3.8545 0.1057
SiHa GDSC1 0.1134 3.8878 -4.6251 2.6981
HT-3 GDSC1 0.1978 2.1526 -3.9471 0.2107
SKG-IIIa GDSC1 0.2037 2.3543 -4.0136 0.329
C-4-I GDSC1 0.236 2.3246 -3.992 0.2781
PEO1 GDSC1 0.3003 3.3953 -4.3511 1.2921
NEC8 GDSC1 0.332 2.2237 -3.9249 0.1534
DoTc2 4510 GDSC1 0.3553 9.6582 -7.063 15.2884
Ca Ski GDSC1 0.3778 3.0069 -4.1782 0.6634
OVCA420 GDSC1 0.4254 2.5554 -4.004 0.2512
SW756 GDSC1 0.4682 2.1476 -3.8544 0.0668
JAR GDSC1; GDSC2 0.4696 2.4895 -1.7257 1.6398
BPH-1 GDSC1 0.4959 3.1637 -4.1894 0.6394
TC-YIK GDSC1 0.5159 2.929 -4.0997 0.4103
NT2-D1 GDSC1 0.5641 2.4185 -3.9111 0.105
MS751 GDSC1 0.6385 3.9283 -4.412 1.2773
DSH1 GDSC1 0.6632 2.4786 -3.8979 0.0827
SKN GDSC1 0.694 4.1031 -4.4546 1.3967
SiSo GDSC1 0.6977 2.7689 -3.9819 0.1645
ME-180 GDSC1 0.7564 3.2736 -4.1322 0.4012
SW954 GDSC2 0.9353 3.0788 -1.7411 1.2617
JEG-3 GDSC1; GDSC2 0.9729 2.5123 -1.5063 0.3945
UWB1.289 GDSC1; GDSC2 1.3319 3.9084 -1.8904 1.4571
OVCA433 GDSC1; GDSC2 1.4151 7.3228 -3.362 8.6725
SW962 GDSC1; GDSC2 1.5283 3.17 -1.5305 0.2415
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 1.6306 3.539 -1.6228 0.3975
ACC-OV7 GDSC1; GDSC2 1.7466 4.6052 -1.9783 1.4402
JHOS-3 GDSC1; GDSC2 1.8422 3.8564 -1.6558 0.3911
OV17R GDSC1; GDSC2 2.0779 4.3805 -1.7538 0.5245
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases. ACS Chem Biol. 2013 Jul 19;8(7):1488-96.