General Information of Drug (ID: )

Drug Name
Synonyms
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw)
Logarithm of the Partition Coefficient (xlogp)
Rotatable Bond Count (rotbonds)
Hydrogen Bond Donor Count (hbonddonor)
Hydrogen Bond Acceptor Count (hbondacc)
ADMET Property
Absorption AUC
The area under the plot of plasma concentration (AUC) of drug is 642870000 mgh/L [1]
Absorption Tmax
The time to maximum plasma concentration (Tmax) is 2-4 h [1]
Bioavailability
The bioavailability of drug is 90% [1]
Clearance
The clearance of drug is 45 mL/min [2]
Half-life
The concentration or amount of drug in body reduced by one-half in 2.7 - 5.5 hours [2]
Metabolism
The drug is metabolized via the cytochrome P450 3A4, 2C8, and 2C9 isoenzymes [2]
Vd
The volume of distribution (Vd) of drug is 8-11 L [2]
Cross-matching ID

References

1 Summary of product characteristics
2 Singulair (montelukast sodium) US FDA Label 2019