Details of the Drug

General Information of Drug (ID: DMQ2AIJ)

Drug Name
Lestaurtinib
Synonyms A 1544750; CEP 701; KT 5555; KT5555; SP 924; CEP-701; KT-5555; SPM-924; Lestaurtinib (USAN/INN)
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Approved (orphan drug) [1]
Myeloid leukaemia 2B33.1 Phase 3 [1]
Psoriasis vulgaris EA90 Phase 2/3 [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 439.5
Logarithm of the Partition Coefficient (xlogp) 2.2
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C26H21N3O4
IUPAC Name
(15S,16S,18R)-16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaen-3-one
Canonical SMILES
C[C@@]12[C@](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
InChI
InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1
InChIKey
UIARLYUEJFELEN-LROUJFHJSA-N
Cross-matching ID
PubChem CID
126565
ChEBI ID
CHEBI:91471
CAS Number
111358-88-4
UNII
DO989GC5D1
DrugBank ID
DB06469
TTD ID
D0V9WF
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fms-like tyrosine kinase 3 (FLT-3) TTGJCWZ FLT3_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Acute myeloid leukaemia
ICD Disease Classification 2A60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fms-like tyrosine kinase 3 (FLT-3) DTT FLT3 2.11E-01 -0.05 -0.16
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 -0.5091 4.0025 -1.8898 22.8825
ES5 GDSC1; GDSC2 -3.7611 3.5016 -5.0428 48.584
ES7 GDSC1; GDSC2 -3.1579 0.6913 -3.4572 42.6634
ES8 GDSC1; GDSC2 -2.9875 -0.9429 -3.0128 40.1279
U2OS GDSC1; GDSC2 -2.938 0.6318 -3.2029 40.5072
EW-12 GDSC2 -2.8945 0.6351 -3.1563 40.0847
ES1 GDSC1; GDSC2 -2.3705 2.8863 -3.3228 37.5954
EW-11 GDSC1; GDSC2 -2.3447 3.1351 -3.394 37.678
SK-PN-DW GDSC1; GDSC2 -2.3265 1.0875 -2.6546 34.8987
TC-71 GDSC1; GDSC2 -2.0725 1.8624 -2.6228 33.4262
HuO9 GDSC1; GDSC2 -1.6041 4.0069 -2.9911 32.6292
MHH-ES-1 GDSC1; GDSC2 -1.5716 3.132 -2.5799 30.787
HOS GDSC1; GDSC2 -1.5408 0.8904 -1.7437 26.5481
CHSA0108 GDSC1; GDSC2 -1.5193 5.5181 -3.5932 34.3438
SK-ES-1 GDSC1; GDSC2 -1.4195 3.1632 -2.4346 29.4323
ES4 GDSC1; GDSC2 -1.2514 6.3329 -3.7153 33.5947
MG-63 GDSC1; GDSC2 -1.1499 3.8787 -2.4718 28.409
SJSA-1 GDSC1; GDSC2 -1.0438 4.2464 -2.5325 28.2322
A-673 GDSC1; GDSC2 -0.9104 3.151 -1.9037 24.5806
EW-3 GDSC1; GDSC2 -0.9027 5.8752 -3.1609 30.2646
HuO-3N1 GDSC1; GDSC2 -0.7066 5.1999 -2.6494 27.3766
H-EMC-SS GDSC1; GDSC2 -0.6783 5.1345 -2.5909 27.003
SaOS-2 GDSC1; GDSC2 -0.6121 9.7879 -4.8005 34.1905
EW-18 GDSC1; GDSC2 -0.55 3.3742 -1.6387 21.6765
EW-16 GDSC1; GDSC2 -0.3466 5.7671 -2.5815 25.6869
EW-22 GDSC1; GDSC2 -0.2673 5.4668 -2.361 24.3573
EW-7 GDSC1; GDSC2 -0.0842 3.7175 -1.3421 18.2121
CHSA0011 GDSC1; GDSC2 -0.046 8.3341 -3.5715 28.6116
EW-1 GDSC1; GDSC2 0.3011 3.843 -1.039 15.0454
CAL-72 GDSC1; GDSC2 0.321 5.9826 -2.0776 20.8594
CADO-ES1 GDSC1; GDSC2 0.4351 5.0449 -1.5106 17.3808
NOS-1 [Human HNSCC] GDSC1; GDSC2 0.4403 7.2899 -2.6227 23.1231
CAL-78 GDSC1; GDSC2 0.7794 11.2747 -4.3223 28.4852
NY GDSC1; GDSC2 0.8504 7.7628 -2.5068 21.2777
EW-13 GDSC1; GDSC2 1.2043 5.3599 -1.0121 12.0701
U-CH2 GDSC2 1.53 5.9587 -1.0527 11.4245
EW-24 GDSC1; GDSC2 1.7771 8.2673 -2.0081 16.1318
ES6 GDSC1; GDSC2 1.975 11.5645 -3.4933 22.305
CHSA8926 GDSC1; GDSC2 2.0158 20.0139 -7.6743 32.9297
G-292 clone A141B1 GDSC1; GDSC2 2.4769 9.606 -2.1428 15.0503
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 -2.6179 -0.4119 -2.6711 36.5585
MV4-11 GDSC1; GDSC2 -8.4065 -5.4617 -8.4089 87.5973
MOLM-13 GDSC1; GDSC2 -7.1915 -4.3328 -7.1963 79.2519
MOLM-16 GDSC1; GDSC2 -7.1066 -2.9316 -7.1592 75.5296
EoL-1 GDSC1; GDSC2 -6.2854 -3.4605 -6.2943 71.6416
Mono-Mac-6 GDSC1; GDSC2 -5.8347 -1.1977 -5.9941 65.0712
OCI-Ly7 GDSC1; GDSC2 -5.6311 -3.5209 -5.633 66.2585
SUP-B8 GDSC1; GDSC2 -5.5039 0.6404 -6.0031 60.7367
KE-37 GDSC1; GDSC2 -5.3714 -2.6265 -5.3866 63.327
697 GDSC1; GDSC2 -5.3503 -2.4064 -5.3735 62.9665
TALL-1 [Human adult T-ALL] GDSC2 -4.9935 2.9603 -6.1644 56.0297
NKM-1 GDSC1; GDSC2 -4.9704 -0.5771 -5.1628 58.35
Kasumi-1 GDSC1; GDSC2 -4.9013 -2.2383 -4.9198 58.895
L-1236 GDSC1; GDSC2 -4.7712 -1.104 -4.8732 57.1289
KMS-12-BM GDSC1; GDSC2 -4.7353 -2.1587 -4.7528 57.3271
JVM-3 GDSC1; GDSC2 -4.6375 0.8476 -5.1114 54.9881
BONNA-12 GDSC2 -4.5498 0.4053 -4.9053 54.5582
JeKo-1 GDSC1; GDSC2 -4.5104 -2.3392 -4.5179 55.2262
NK-92MI GDSC2 -4.4066 -2.983 -4.4069 54.252
RCH-ACV GDSC1; GDSC2 -4.339 -1.5717 -4.3748 53.4414
OCI-Ly19 GDSC1; GDSC2 -4.3087 0.7759 -4.734 52.591
Karpas-231 GDSC1; GDSC2 -4.3041 -1.863 -4.3227 53.154
ATN-1 GDSC1; GDSC2 -4.2968 -2.889 -4.2972 53.1515
L-540 GDSC1; GDSC2 -4.2772 -2.2769 -4.2827 52.9318
ALL-PO GDSC1; GDSC2 -4.1856 -1.4672 -4.2224 51.9659
BV-173 GDSC1; GDSC2 -4.1626 0.4495 -4.4938 51.4987
Karpas-1106P GDSC1; GDSC2 -4.1368 -1.1826 -4.1944 51.4735
SR GDSC1; GDSC2 -4.1324 -1.748 -4.1514 51.4741
NB4 GDSC1; GDSC2 -4.0965 -1.5575 -4.1242 51.1134
SU-DHL-5 GDSC1; GDSC2 -4.0381 -1.6047 -4.0612 50.5452
SU-DHL-16 GDSC1; GDSC2 -4.0194 -2.9994 -4.0194 50.3698
MOLT-16 GDSC1; GDSC2 -3.9661 -1.8865 -3.976 49.8367
RS4;11 GDSC1; GDSC2 -3.9152 0.2332 -4.1759 49.4144
RPMI-8866 GDSC1; GDSC2 -3.8799 -0.0329 -4.0833 49.0834
MLMA GDSC1; GDSC2 -3.8147 -0.5485 -3.9269 48.4298
A3/Kawakami GDSC1; GDSC2 -3.7789 0.0645 -3.993 48.1811
A4/Fukuda GDSC1; GDSC2 -3.7696 0.9557 -4.1932 48.2475
NU-DUL-1 GDSC1; GDSC2 -3.7157 -1.1841 -3.7536 47.3936
Karpas-45 GDSC1; GDSC2 -3.6915 -1.847 -3.6978 47.0955
PL-21 GDSC1; GDSC2 -3.6657 0.5781 -3.9831 47.2701
Farage GDSC1; GDSC2 -3.5889 -0.564 -3.6838 46.2593
RPMI-8402 GDSC1; GDSC2 -3.5865 -2.2417 -3.5872 46.0283
WSU-NHL GDSC1 -3.5794 -0.925 -3.6328 56.7155
DEL GDSC1; GDSC2 -3.5632 -0.8018 -3.6281 45.952
KOPN-8 GDSC1; GDSC2 -3.5531 0.0339 -3.7424 46.0833
SUP-HD1 GDSC1; GDSC2 -3.5021 1.1669 -3.9598 46.0276
Hs 445 GDSC2 -3.5021 0.1986 -3.7199 45.6602
P30/OHK GDSC1; GDSC2 -3.4629 -1.1193 -3.4949 44.8859
JURL-MK1 GDSC1; GDSC2 -3.4606 0.9324 -3.8497 45.5705
SIG-M5 GDSC2 -3.4497 -2.5061 -3.4497 44.6531
SUP-M2 GDSC1; GDSC2 -3.4259 -2.234 -3.4262 44.4155
H9 GDSC1; GDSC2 -3.4219 -1.1243 -3.4519 44.4739
GA-10 GDSC1; GDSC2 -3.3722 0.3168 -3.6038 44.4854
CRO-AP2 GDSC1; GDSC2 -3.3528 -1.1204 -3.3805 43.7802
MHH-PREB-1 GDSC1; GDSC2 -3.3304 0.1758 -3.529 44.0213
BC-3 GDSC2 -3.3277 -1.4346 -3.339 43.4732
NALM-6 GDSC1; GDSC2 -3.3155 -0.8623 -3.3613 43.4677
SU-DHL-6 GDSC1; GDSC2 -3.2897 -0.9273 -3.3288 43.1903
YT GDSC1; GDSC2 -3.2648 -0.1967 -3.3907 43.209
MOLT-4 GDSC1; GDSC2 -3.2514 -0.9565 -3.2865 42.7969
OCI-M1 GDSC1; GDSC2 -3.0646 -1.4843 -3.0697 40.8122
QIMR-WIL GDSC1; GDSC2 -3.0643 1.7366 -3.6565 42.5323
BL-41 GDSC1; GDSC2 -3.023 -1.5907 -3.0258 40.3846
JSC-1 GDSC1; GDSC2 -3.0223 0.5673 -3.2795 41.2794
ALL-SIL GDSC1; GDSC2 -2.9888 -0.5107 -3.0527 40.2967
SKM-1 GDSC1; GDSC2 -2.9421 0.6548 -3.213 40.5651
P12-Ichikawa GDSC1 -2.9245 1.4279 -3.407 49.2777
LAMA-84 GDSC1; GDSC2 -2.9232 3.1068 -3.9969 42.3908
CTB-1 GDSC1; GDSC2 -2.9165 4.7878 -4.6821 43.4954
MOLP-8 GDSC1; GDSC2 -2.9081 -0.7285 -2.946 39.3877
P32/ISH GDSC1; GDSC2 -2.9074 -1.3069 -2.9142 39.2439
AMO1 GDSC1; GDSC2 -2.8864 -0.4291 -2.9536 39.2938
NCI-H929 GDSC1; GDSC2 -2.8687 -0.8456 -2.8958 38.9473
RPMI-6666 GDSC1; GDSC2 -2.791 2.7333 -3.7127 41.0121
JJN-3 GDSC1; GDSC2 -2.7773 -0.5982 -2.8204 38.1049
L-363 GDSC1; GDSC2 -2.7002 0.5782 -2.9313 38.113
SU-DHL-10 GDSC2 -2.6459 -1.4374 -2.6473 36.594
HAL-01 GDSC1; GDSC2 -2.5901 0.5624 -2.8078 36.9926
KY821 GDSC1; GDSC2 -2.5829 0.7621 -2.8478 37.1129
MOLT-13 GDSC1; GDSC2 -2.5807 0.5138 -2.7865 36.8523
VAL GDSC1; GDSC2 -2.5742 0.6185 -2.8035 36.8854
ML-2 GDSC1; GDSC2 -2.5736 -0.528 -2.6129 36.0509
DND-41 GDSC1; GDSC2 -2.5536 0.9638 -2.8683 37.0268
OCI-AML-5 GDSC1; GDSC2 -2.545 0.4126 -2.7257 36.3974
SCC-3 GDSC2 -2.4765 1.733 -3.0168 37.1491
Ramos.2G6.4C10 GDSC1; GDSC2 -2.4671 -0.5366 -2.5004 34.9557
WSU-DLCL2 GDSC1; GDSC2 -2.4387 -0.1332 -2.515 34.8767
NOMO-1 GDSC1; GDSC2 -2.4245 0.9526 -2.7244 35.7258
DoHH2 GDSC1; GDSC2 -2.3767 -1.248 -2.3781 33.8923
MEG-01 GDSC1; GDSC2 -2.3766 2.4393 -3.1583 37.0922
CTV-1 GDSC1; GDSC2 -2.3631 -0.3166 -2.4122 33.9908
MM1.S GDSC1; GDSC2 -2.3583 -0.2315 -2.4168 33.9883
Jurkat GDSC1; GDSC2 -2.3454 0.6247 -2.5557 34.5666
OCI-AML-2 GDSC1; GDSC2 -2.3434 2.0139 -2.9685 36.2404
Jiyoye GDSC1; GDSC2 -2.2686 -0.3127 -2.3128 33.0202
HL-60 GDSC1; GDSC2 -2.2565 2.0153 -2.8751 35.42
GR-ST GDSC1; GDSC2 -2.2323 1.1239 -2.5621 33.9944
SUP-B15 GDSC1; GDSC2 -2.2272 0.8668 -2.4864 33.628
CCRF-CEM GDSC1; GDSC2 -2.2185 0.5474 -2.4 33.1818
SU-DHL-1 GDSC2 -2.1723 0.9128 -2.4386 33.1229
GDM-1 GDSC1; GDSC2 -2.1698 0.0642 -2.256 32.2379
EJM GDSC1; GDSC2 -2.1238 0.441 -2.2744 32.0945
CMK GDSC1 -2.1157 0.6811 -2.3188 39.927
MHH-CALL-4 GDSC2 -2.1058 0.6566 -2.3023 32.1376
TUR GDSC1; GDSC2 -2.102 2.2556 -2.7954 34.2951
EM-2 GDSC1; GDSC2 -2.0715 1.5723 -2.5241 32.9897
OCI-AML-3 GDSC1; GDSC2 -2.0459 1.2032 -2.3817 32.2093
BE-13 GDSC1; GDSC2 -2.0208 3.3544 -3.1425 35.1861
Namalwa GDSC1; GDSC2 -1.9907 3.5769 -3.2043 35.2517
RL GDSC1; GDSC2 -1.9008 0.6284 -2.0726 29.9789
U266B1 GDSC1; GDSC2 -1.8822 5.252 -3.8324 36.671
TK [Human B-cell lymphoma] GDSC1; GDSC2 -1.8478 3.8333 -3.1657 34.4207
WIL2 NS GDSC1; GDSC2 -1.817 1.7783 -2.3172 30.7631
Granta-519 GDSC1; GDSC2 -1.8095 2.5518 -2.5952 31.9891
KMOE-2 GDSC1; GDSC2 -1.7699 1.9559 -2.3289 30.589
KG-1 GDSC1; GDSC2 -1.7586 2.8709 -2.6684 32.0561
HEL GDSC1; GDSC2 -1.6983 1.9887 -2.2635 29.9312
MC116 GDSC1; GDSC2 -1.5722 -0.6288 -1.5743 25.8231
RPMI-8226 GDSC1; GDSC2 -1.5606 0.9118 -1.7709 26.7846
Daudi GDSC1; GDSC2 -1.5306 1.0109 -1.7647 26.6102
PF-382 GDSC1; GDSC2 -1.4041 2.401 -2.1052 27.7774
P31/FUJ GDSC1; GDSC2 -1.4003 3.4211 -2.5254 29.7581
HDLM-2 GDSC1; GDSC2 -1.3859 2.4696 -2.1131 27.7338
MY-M12 GDSC1; GDSC2 -1.3836 3.1549 -2.3938 29.0806
CML-T1 GDSC1; GDSC2 -1.1353 2.0467 -1.6812 24.3587
Loucy GDSC1; GDSC2 -1.13 2.12 -1.7037 24.4568
KMS-11 GDSC1; GDSC2 -1.1152 2.132 -1.6926 24.3316
SU-DHL-4 GDSC1; GDSC2 -1.0625 -0.2843 -1.0646 20.708
SU-DHL-8 GDSC2 -0.9976 2.7458 -1.8187 24.499
OPM-2 GDSC1; GDSC2 -0.9387 0.0196 -0.9488 19.5059
Karpas-620 GDSC1; GDSC2 -0.9125 3.9487 -2.2647 26.4219
Karpas-422 GDSC1; GDSC2 -0.9083 1.5441 -1.253 21.0048
KCL-22 GDSC1; GDSC2 -0.8981 1.6925 -1.2946 21.1912
Reh GDSC1; GDSC2 -0.8657 3.6581 -2.0852 25.3343
SUP-T1 GDSC1; GDSC2 -0.8219 4.9509 -2.6426 27.808
MHH-CALL-2 GDSC1 -0.8137 2.2445 -1.4177 26.6494
DB GDSC1; GDSC2 -0.7892 5.3143 -2.7835 28.2887
Ku812 GDSC1; GDSC2 -0.7734 4.6802 -2.4674 26.8173
ST486 GDSC1 -0.7612 3.2719 -1.8053 28.702
THP-1 GDSC1; GDSC2 -0.7379 2.1874 -1.3147 20.6173
ARH-77 GDSC1; GDSC2 -0.6727 1.1697 -0.8744 17.8582
IM-9 GDSC1; GDSC2 -0.6399 1.7317 -1.0317 18.5951
HH [Human lymphoma] GDSC1; GDSC2 -0.5776 3.6387 -1.7879 22.6042
CESS GDSC1; GDSC2 -0.5523 4.4143 -2.1263 24.2812
EHEB GDSC1 -0.4491 3.2267 -1.4702 25.0416
Sc-1 GDSC1 -0.4392 2.0558 -0.9464 21.4676
DG-75 GDSC1; GDSC2 -0.2576 4.2984 -1.7866 21.3655
BALL-1 GDSC1; GDSC2 -0.2415 4.0025 -1.6296 20.4383
HT GDSC1; GDSC2 -0.0923 2.5667 -0.811 15.0873
BC-1 GDSC1; GDSC2 0.0222 2.647 -0.7333 14.1862
Karpas-299 GDSC1; GDSC2 0.0991 5.1308 -1.8571 20.4563
VL51 GDSC1; GDSC2 0.111 6.7114 -2.6266 24.2497
HC-1 GDSC1; GDSC2 0.1812 7.6046 -3.0072 25.667
U-698-M GDSC1; GDSC2 0.4375 4.1184 -1.0497 14.6498
LC4-1 GDSC1; GDSC2 0.6054 12.0202 -4.8423 30.4849
L-428 GDSC1; GDSC2 0.7574 3.9912 -0.7023 11.4846
Raji GDSC1; GDSC2 0.8394 3.2532 -0.2631 8.4756
MN-60 GDSC1; GDSC2 0.8704 8.819 -3.018 23.5006
CA46 GDSC1; GDSC2 0.9951 5.1362 -1.0722 13.0387
KM-H2 GDSC1; GDSC2 1.2509 3.74 -0.1669 6.6892
SK-MM-2 GDSC1; GDSC2 1.3152 5.413 -0.9496 11.3822
RC-K8 GDSC1 1.5961 3.4404 0.2337 4.1944
ME1 GDSC1; GDSC2 1.6505 7.8243 -1.8863 15.8313
EB2 GDSC1; GDSC2 1.688 4.7275 -0.3261 6.5888
K-562 GDSC1; GDSC2 1.8575 5.3389 -0.503 7.2767
JVM-2 GDSC1; GDSC2 1.9083 8.972 -2.2566 17.0474
LP-1 GDSC1; GDSC2 1.955 3.6409 0.3649 1.9489
ROS-50 GDSC1; GDSC2 2.5945 7.7527 -1.1576 9.491
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC1; GDSC2 -1.6599 6.3599 -4.1255 36.4712
OACP4 C GDSC1; GDSC2 -1.2743 3.6129 -2.4797 28.9883
ESO-51 GDSC1; GDSC2 -1.0916 0.964 -1.2729 21.9407
SK-GT-4 GDSC1; GDSC2 -1.0236 5.5382 -3.1169 30.5867
ESO-26 GDSC1; GDSC2 -0.7612 4.4805 -2.3616 26.2694
KYSE-220 GDSC1; GDSC2 -0.6303 4.1012 -2.0552 24.2257
TE-12 GDSC1; GDSC2 0.6502 9.9551 -3.7723 27.0717
HCE-4 GDSC1; GDSC2 0.789 8.4614 -2.908 23.2815
KYSE-50 GDSC1; GDSC2 0.8584 6.0855 -1.6617 16.8875
OACM5.1 C GDSC1; GDSC2 1.6472 3.9169 0.0394 4.438
KYAE-1 GDSC1; GDSC2 2.072 3.9193 0.3073 2.0788
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 -0.3539 1.8339 -0.7665 15.8678
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-14 GDSC1; GDSC2 -4.5021 -0.1098 -4.7421 54.4105
Kelly GDSC1; GDSC2 -4.0028 -1.8627 -4.0142 50.2016
SK-N-MC-IXC GDSC1; GDSC2 -3.5717 2.5667 -4.4904 47.0662
CHP-212 GDSC1; GDSC2 -3.1308 -0.2232 -3.2426 41.8653
NH-12 GDSC1; GDSC2 -2.7107 0.4911 -2.9228 38.1415
TGW GDSC1; GDSC2 -2.2883 -0.5159 -2.3152 33.1323
SK-N-AS GDSC1; GDSC2 -1.9723 1.3004 -2.3305 31.5967
IMR-5 GDSC1; GDSC2 -1.6606 0.2456 -1.7379 27.0942
SiMa GDSC1; GDSC2 -1.5638 1.2112 -1.8584 27.256
SK-N-BE(2)-M17 GDSC1; GDSC2 -1.4748 2.9156 -2.3883 29.4711
SK-N-SH GDSC1; GDSC2 -1.4263 3.0429 -2.3908 29.2603
CHP-126 GDSC1; GDSC2 -1.3702 1.7948 -1.8403 26.2615
MHH-NB-11 GDSC1; GDSC2 -1.3016 2.5089 -2.0396 26.9826
SJNB-17 GDSC1; GDSC2 -1.3012 0.9822 -1.5065 24.167
GI-ME-N GDSC1; GDSC2 -1.1377 8.2757 -4.5434 35.4365
NB69 GDSC1; GDSC2 -1.0329 0.9117 -1.1951 21.2502
KP-N-YS GDSC1; GDSC2 -0.9968 0.8946 -1.1513 20.847
SJNB-5 GDSC1; GDSC2 -0.9734 2.2566 -1.5912 23.1622
SJNB-13 GDSC1; GDSC2 -0.8964 5.0274 -2.7513 28.5842
SJNB-10 GDSC1; GDSC2 -0.8145 2.0345 -1.3347 21.0545
SJNB-6 GDSC1; GDSC2 -0.7148 2.8819 -1.5849 22.0413
SJNB-7 GDSC1; GDSC2 -0.6531 1.5635 -0.9842 18.3833
NB1 GDSC1; GDSC2 -0.6409 4.2731 -2.1463 24.7312
SJNB-12 GDSC1; GDSC2 -0.5674 7.3454 -3.5579 30.4136
GOTO GDSC1; GDSC2 -0.3974 3.8438 -1.7059 21.4527
KP-N-YN GDSC1; GDSC2 0.0836 4.0475 -1.3417 17.6053
KP-N-RT-BM-1 GDSC2 0.2699 3.8321 -1.0626 15.2949
NB(TU)1 GDSC1; GDSC2 0.4913 2.0612 0.0028 7.9667
SK-N-FI GDSC1; GDSC2 0.5665 10.0881 -3.9101 27.8002
SK-N-DZ GDSC1; GDSC2 0.6721 6.8052 -2.1802 20.2358
LA-N-6 GDSC1; GDSC2 0.6991 4.8912 -1.2017 14.7194
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 0.3864 6.7328 -2.3926 22.2172
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1; GDSC2 -2.9803 -1.2345 -2.9909 39.9916
HCC2157 GDSC1; GDSC2 -2.1494 1.1181 -2.47 33.1482
HCC1806 GDSC1; GDSC2 -1.9041 1.2204 -2.2322 30.7845
HCC1187 GDSC1; GDSC2 -1.827 2.8013 -2.7126 32.5744
MDA-MB-468 GDSC1; GDSC2 -1.3714 2.5902 -2.1462 27.8333
EFM-19 GDSC1; GDSC2 -1.3217 2.8115 -2.1847 27.7992
BT-549 GDSC1; GDSC2 -1.1327 5.1054 -3.0194 30.6625
MFM-223 GDSC1; GDSC2 -1.0559 2.4946 -1.7749 24.516
MDA-MB-361 GDSC1; GDSC2 -0.9903 1.7092 -1.4 22.1806
CAL-51 GDSC1; GDSC2 -0.8837 5.4082 -2.9196 29.2368
Evsa-T GDSC1; GDSC2 -0.8587 2.8404 -1.715 23.3533
MDA-MB-231 GDSC1; GDSC2 -0.6437 3.1092 -1.6132 21.9096
MDA-MB-330 GDSC1; GDSC2 -0.3265 2.9089 -1.2021 18.307
HDQ-P1 GDSC1; GDSC2 -0.2166 3.6262 -1.4267 19.1925
CAL-120 GDSC1; GDSC2 -0.2093 9.7656 -4.4273 31.8662
OCUB-M GDSC1; GDSC2 0.2619 3.8928 -1.0997 15.5462
MDA-MB-175-VII GDSC1; GDSC2 0.3467 4.5044 -1.3226 16.5841
MDA-MB-453 GDSC1; GDSC2 0.395 5.0923 -1.5699 17.8526
COLO 824 GDSC1; GDSC2 0.4177 6.262 -2.1308 20.8101
HCC1599 GDSC2 0.4529 6.6413 -2.2886 21.4887
Hs 578T GDSC1; GDSC2 0.4779 6.1631 -2.0286 20.0832
CAL-148 GDSC2 0.5478 6.3787 -2.0749 20.0954
HCC1143 GDSC1; GDSC2 0.7142 5.7699 -1.6271 17.1421
MDA-MB-436 GDSC1; GDSC2 0.7236 5.225 -1.3471 15.503
HCC1569 GDSC1; GDSC2 0.7822 4.6758 -1.0224 13.3798
MDA-MB-415 GDSC1; GDSC2 0.9395 3.64 -0.3707 8.8522
JIMT-1 GDSC1; GDSC2 1.0903 6.4215 -1.6359 16.045
MRK-nu-1 GDSC1; GDSC2 1.1158 6.1742 -1.4912 15.1518
MDA-MB-157 GDSC1; GDSC2 1.1545 7.7796 -2.2619 19.1706
EFM-192A GDSC1; GDSC2 1.2306 4.2446 -0.4343 8.4247
HCC38 GDSC1; GDSC2 1.2738 5.1015 -0.8273 10.7485
HCC1937 GDSC1; GDSC2 1.3099 6.181 -1.337 13.7051
AU565 GDSC1; GDSC2 1.3386 6.8472 -1.6464 15.3874
HCC70 GDSC1; GDSC2 1.4173 5.587 -0.9556 11.1408
HCC1419 GDSC1; GDSC2 1.5117 3.0989 0.3403 2.9024
HCC1395 GDSC1; GDSC2 1.5308 8.2346 -2.185 17.7087
BT-20 GDSC1; GDSC2 1.6919 7.4911 -1.6885 14.6505
HCC1428 GDSC1; GDSC2 1.7089 5.3778 -0.6299 8.4048
MCF-7 GDSC1; GDSC2 1.7792 11.0959 -3.4142 22.5148
BT-474 GDSC1; GDSC2 1.8355 9.2819 -2.4669 18.2623
ZR-75-30 GDSC1; GDSC2 1.9899 8.19 -1.8071 14.517
YMB-1-E GDSC2 2.0917 5.9075 -0.6142 7.419
HCC2218 GDSC1; GDSC2 2.2652 5.1021 -0.117 4.127
HCC202 GDSC1 2.4222 4.5348 0.2298 2.466
UACC-893 GDSC1; GDSC2 2.6641 10.4287 -2.4097 15.9091
CAMA-1 GDSC1; GDSC2 2.9089 12.8223 -3.4056 19.665
HCC1954 GDSC1; GDSC2 3.1431 8.8789 -1.3286 9.3004
UACC-812 GDSC2 3.2951 5.4277 0.2827 0.8747
BT-483 GDSC1; GDSC2 3.6734 12.3337 -2.6234 14.6645
HCC1500 GDSC1; GDSC2 3.9033 11.9641 -2.2922 12.6735
CAL-85-1 GDSC1; GDSC2 3.9174 13.5829 -3.0574 16.0441
T-47D GDSC1; GDSC2 4.861 15.0701 -3.1362 14.5402
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC1; GDSC2 -5.026 0.8891 -5.5464 57.5833
D283 Med GDSC1; GDSC2 -4.7074 -0.7912 -4.8468 56.4172
D-566MG GDSC1; GDSC2 -2.1254 3.1031 -3.1495 35.7393
SF539 GDSC1; GDSC2 -2.1223 2.2583 -2.8182 34.4915
ONS-76 GDSC1; GDSC2 -2.1187 2.0979 -2.7558 34.2214
42-MG-BA GDSC1; GDSC2 -1.8513 2.5468 -2.6378 32.3778
LNZTA3WT4 GDSC1; GDSC2 -1.7528 1.5314 -2.1644 29.7118
SW1088 GDSC1; GDSC2 -1.6563 1.341 -1.9987 28.4171
8-MG-BA GDSC1; GDSC2 -1.5477 11.2902 -6.3969 40.2884
MOG-G-UVW GDSC1; GDSC2 -1.5448 7.4651 -4.5386 37.0023
YH-13 GDSC1; GDSC2 -1.4433 1.8838 -1.951 27.1731
MOG-G-CCM GDSC1; GDSC2 -1.3193 4.9134 -3.1145 31.8238
D-336MG GDSC1; GDSC2 -1.3056 4.371 -2.8518 30.7351
T98G GDSC1; GDSC2 -1.2467 1.0208 -1.4576 23.6522
GI-1 GDSC1; GDSC2 -1.0326 2.4861 -1.7468 24.2642
YKG-1 GDSC1; GDSC2 -1.015 7.4504 -4.0272 33.5935
SF268 GDSC1; GDSC2 -0.9675 3.5375 -2.1337 26.0045
LN-18 GDSC1; GDSC2 -0.924 2.4041 -1.599 22.9939
GaMG GDSC1; GDSC2 -0.8798 5.0595 -2.7504 28.5126
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -0.8794 5.215 -2.8237 28.8221
KALS-1 GDSC1; GDSC2 -0.8585 1.6294 -1.2293 20.6536
A-172 GDSC1; GDSC2 -0.8414 4.2728 -2.3435 26.5095
SF126 GDSC1; GDSC2 -0.7912 3.2665 -1.8333 23.7113
Becker GDSC1; GDSC2 -0.7747 2.9194 -1.6629 22.7191
GB-1 GDSC1; GDSC2 -0.7645 6.8778 -3.5136 31.002
M059J GDSC1; GDSC2 -0.6654 4.8555 -2.4454 26.2829
SF295 GDSC1; GDSC2 -0.5651 3.053 -1.5082 21.0065
SK-MG-1 GDSC1; GDSC2 -0.5447 3.7186 -1.7923 22.4981
KINGS-1 GDSC1; GDSC2 -0.2896 9.3292 -4.2828 31.7236
D-247MG GDSC1; GDSC2 -0.2422 8.8827 -4.0191 30.7717
D-502MG GDSC1; GDSC2 -0.1983 9.9871 -4.5274 32.1064
Hs 683 GDSC1; GDSC2 -0.1362 5.3825 -2.1976 23.0717
D-263MG GDSC1; GDSC2 -0.0208 3.7234 -1.284 17.641
SW1783 GDSC1; GDSC2 0.0202 5.6266 -2.1732 22.3876
D-392MG GDSC1; GDSC2 0.0467 6.8828 -2.7693 25.1114
Daoy GDSC1; GDSC2 0.1191 6.3232 -2.4271 23.2903
D-423MG GDSC1; GDSC2 0.1353 7.4604 -2.9764 25.6942
DK-MG GDSC1; GDSC2 0.1807 10.8444 -4.6206 31.1548
U-118MG GDSC1; GDSC2 0.2883 7.0638 -2.6436 23.7232
CAS-1 GDSC1; GDSC2 0.4423 5.7409 -1.8499 19.2491
AM-38 GDSC1; GDSC2 0.7258 5.3107 -1.3879 15.7347
SNB-75 GDSC1; GDSC2 0.7409 2.9922 -0.2195 8.5081
D-245MG GDSC2 0.7685 8.1602 -2.7748 22.7618
NMC-G1 GDSC1; GDSC2 0.9432 9.5543 -3.3246 24.527
KNS-81-FD GDSC1; GDSC2 1.0402 6.4308 -1.682 16.4507
LN-405 GDSC1; GDSC2 1.0813 5.9739 -1.4195 14.8405
LN-229 GDSC1; GDSC2 1.2176 7.1453 -1.8932 17.0811
DBTRG-05MG GDSC1; GDSC2 1.2883 10.804 -3.6638 24.8084
Onda 10 GDSC1; GDSC2 1.2994 6.2787 -1.3942 14.0664
PFSK-1 GDSC1 1.4888 8.3898 -2.2959 21.73
U-87MG ATCC GDSC1 1.9294 7.241 -1.3839 14.9492
Onda 11 GDSC1; GDSC2 2.231 9.6831 -2.3632 16.7407
KNS-42 GDSC1; GDSC2 2.3705 7.9069 -1.3886 11.2942
U-251MG GDSC1; GDSC2 2.6535 6.3604 -0.4595 5.3774
D-542MG GDSC1; GDSC2 4.8288 12.7646 -2.0804 9.9939
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 0.104 4.9033 -1.7408 19.8049
TGBC24TKB GDSC1; GDSC2 2.6276 6.277 -0.4369 5.2961
TGBC1TKB GDSC1; GDSC2 3.3914 11.8411 -2.5801 15.0644
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-296 GDSC1; GDSC2 -2.9511 1.9437 -3.6021 41.6994
AN3-CA GDSC1; GDSC2 -1.3555 3.3819 -2.4621 29.2696
ESS-1 GDSC1; GDSC2 -0.9427 1.5351 -1.2871 21.3452
RL95-2 GDSC1; GDSC2 -0.8981 6.6324 -3.5207 31.5434
MFE-319 GDSC1; GDSC2 0.5705 4.3845 -1.0623 14.2906
MFE-280 GDSC1; GDSC2 1.0633 4.4445 -0.6698 10.3667
KLE GDSC1; GDSC2 1.109 7.9375 -2.3783 19.8787
EN GDSC1; GDSC2 1.9361 7.5064 -1.5098 13.0255
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ACHN GDSC1; GDSC2 -3.6924 7.8921 -6.8534 48.7186
KTCTL-140 GDSC1; GDSC2 -3.3593 2.3032 -4.1677 45.3367
CAL-54 GDSC1; GDSC2 -3.0687 4.7902 -4.8407 44.4971
VMRC-RCZ GDSC1; GDSC2 -2.768 5.1743 -4.6971 42.7621
LB996-RCC GDSC2 -2.6351 3.8345 -3.9855 40.7683
BB65-RCC GDSC1; GDSC2 -2.2215 5.7563 -4.4029 39.6082
A-498 GDSC1; GDSC2 -1.6344 3.8141 -2.9374 32.5616
KTCTL-26A GDSC1; GDSC2 -1.5132 5.1323 -3.4084 33.7162
KTCTL-195 GDSC1; GDSC2 -1.4664 3.85 -2.7809 31.1606
LB1047-RCC GDSC1; GDSC2 -1.4027 7.0678 -4.2119 35.6293
LB2241-RCC GDSC1; GDSC2 -1.3332 4.4872 -2.9324 31.1808
KMRC-20 GDSC1; GDSC2 -0.9106 5.2034 -2.8485 29.0526
SW13 GDSC1; GDSC2 -0.8962 5.5211 -2.9854 29.5532
Caki-1 GDSC1; GDSC2 -0.8706 30.8883 -15.5302 44.6901
KTCTL-1M GDSC1; GDSC2 -0.7477 3.7995 -2.0315 24.5749
NCC010 GDSC1; GDSC2 -0.6719 7.5972 -3.7779 31.5357
BFTC-909 GDSC1; GDSC2 -0.6643 4.6515 -2.3476 25.8147
TK-10 GDSC1; GDSC2 -0.6382 6.1488 -3.0409 28.7581
KTCTL-13 GDSC1; GDSC2 -0.4893 5.8213 -2.7418 26.9396
SN12C GDSC1; GDSC2 -0.2509 4.118 -1.6938 20.8307
769-P GDSC1; GDSC2 -0.1874 6.1938 -2.6425 25.3785
KTCTL-21 GDSC1; GDSC2 -0.1517 7.3111 -3.1602 27.4376
HA7-RCC GDSC1; GDSC2 0.0829 4.822 -1.7204 19.7657
RXF 393L GDSC1; GDSC2 0.229 5.6762 -2.0081 20.81
A-704 GDSC1; GDSC2 0.4041 8.9962 -3.5049 26.8829
OS-RC-2 GDSC1; GDSC2 0.4137 9.0798 -3.5383 26.9749
SW156 GDSC1; GDSC2 0.9661 10.3783 -3.7174 25.931
786-O GDSC1; GDSC2 1.2359 5.0783 -0.846 10.9687
UO-31 GDSC1; GDSC2 1.5387 3.6021 0.116 4.2111
KMRC-1 GDSC1; GDSC2 1.703 5.2086 -0.551 7.9359
NCC021 GDSC1; GDSC2 1.9198 8.7454 -2.1354 16.4096
VMRC-RCW GDSC1; GDSC2 2.1034 5.4905 -0.4056 6.145
RCC10RGB GDSC1; GDSC2 4.6663 20.3757 -5.8283 23.7292
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC1; GDSC2 -4.6036 1.4046 -5.2305 54.4887
KM12 GDSC1; GDSC2 -4.4959 2.0394 -5.3108 53.5223
SW48 GDSC1; GDSC2 -3.9612 -0.3942 -4.1073 49.8051
CaR-1 GDSC1; GDSC2 -2.4239 4.7482 -4.1571 40.0546
SNU-175 GDSC2 -2.4224 -0.1781 -2.4916 34.6806
HCT 116 GDSC1; GDSC2 -2.2261 1.8418 -2.7819 34.8902
SK-CO-1 GDSC1; GDSC2 -2.0601 3.4667 -3.2305 35.6866
GP5d GDSC1; GDSC2 -2.0267 3.4695 -3.1967 35.404
HCT 15 GDSC1; GDSC2 -2.0061 5.5966 -4.114 37.968
SNU-C5 GDSC1; GDSC2 -1.9762 3.8772 -3.3174 35.5616
MDST8 GDSC1; GDSC2 -1.8384 4.7186 -3.5467 35.635
COLO205 GDSC1; GDSC2 -1.5149 0.5985 -1.6463 25.9149
NCI-H716 GDSC1; GDSC2 -1.3914 2.0078 -1.9407 26.8819
RKO GDSC1; GDSC2 -1.2122 2.3242 -1.8711 25.7116
SNU-407 GDSC1; GDSC2 -1.0571 3.8776 -2.3776 27.5722
LS411N GDSC1; GDSC2 -0.8528 2.5459 -1.5834 22.6062
SNU-C1 GDSC1; GDSC2 -0.5678 2.986 -1.4809 20.8628
SW620 GDSC1; GDSC2 -0.5233 5.1593 -2.4542 25.7688
HT-29 GDSC1; GDSC2 -0.4902 3.0885 -1.4485 20.3706
C2BBe1 GDSC1; GDSC2 -0.4594 4.2255 -1.9466 22.9901
CL-11 GDSC1; GDSC2 -0.4274 3.6616 -1.6498 21.2582
DiFi GDSC1; GDSC2 -0.395 5.7921 -2.6389 26.1282
NCI-H508 GDSC1; GDSC2 -0.3521 5.8555 -2.6297 25.9265
LS513 GDSC1; GDSC2 -0.1872 2.827 -1.025 16.7264
NCI-H747 GDSC1; GDSC2 -0.0546 2.8724 -0.9139 15.5616
LS180 GDSC1; GDSC2 0.0232 3.4556 -1.1135 16.4712
SNU-C2B GDSC1; GDSC2 0.13 4.4007 -1.4705 18.1892
HCC2998 GDSC1; GDSC2 0.1508 7.4862 -2.9754 25.6371
HT115 GDSC1; GDSC2 0.1961 4.8178 -1.6143 18.7788
SW626 GDSC1; GDSC2 0.4432 5.0547 -1.5082 17.3404
SW1417 GDSC1; GDSC2 0.5033 9.5215 -3.6814 27.2073
RCM-1 [Human ESC] GDSC1; GDSC2 0.7185 9.2787 -3.3762 25.4099
CCK-81 GDSC1; GDSC2 0.8152 3.3467 -0.3307 8.9762
SW948 GDSC1; GDSC2 1.0656 5.0115 -0.9514 12.0983
SNU-283 GDSC2 1.0662 3.9378 -0.4141 8.7565
COLO 320HSR GDSC1; GDSC2 1.2002 3.6221 -0.1482 6.7072
SW1463 GDSC1; GDSC2 1.217 2.5751 0.3851 3.3059
SW1116 GDSC1; GDSC2 1.358 8.7998 -2.6057 20.2336
LS123 GDSC1; GDSC2 1.6012 11.7018 -3.8585 24.6437
LS1034 GDSC1; GDSC2 1.6598 3.2368 0.372 2.4174
SW837 GDSC1; GDSC2 1.8211 7.258 -1.4738 13.1166
SNU-81 GDSC1; GDSC2 2.1658 8.2695 -1.7149 13.5801
HT-55 GDSC1; GDSC2 2.3727 7.9362 -1.4014 11.3604
CW-2 GDSC1; GDSC2 2.568 6.1795 -0.4288 5.3599
T84 GDSC1; GDSC2 2.9297 8.9347 -1.4972 10.6515
COLO 678 GDSC1; GDSC2 3.7966 19.7386 -6.153 26.2092
SNU-61 GDSC1; GDSC2 3.8509 12.8564 -2.7535 14.878
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 0.9197 2.9718 -0.0536 6.9077
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-HEP-1 GDSC1; GDSC2 -3.0987 5.6958 -5.2654 45.1109
Hep 3B2.1-7 GDSC1; GDSC2 -2.9166 3.5947 -4.1834 42.7019
HuH-1 GDSC1; GDSC2 -1.1277 6.764 -3.8028 33.3652
JHH-7 GDSC1; GDSC2 -0.7745 5.3461 -2.7846 28.2345
JHH-2 GDSC1; GDSC2 -0.5538 5.2086 -2.507 26.1329
SNU-398 GDSC1; GDSC2 -0.3457 3.7575 -1.6147 20.7483
JHH-4 GDSC1; GDSC2 -0.2314 7.2981 -3.2261 27.9779
SNU-423 GDSC1; GDSC2 0.0114 5.1942 -1.9689 21.3631
JHH-1 GDSC1; GDSC2 0.0713 3.4634 -1.0711 16.0441
SNU-387 GDSC1; GDSC2 0.1514 4.4089 -1.4547 18.0231
HLE GDSC1; GDSC2 0.316 5.9476 -2.0647 20.8094
Hep-G2/C3A GDSC1; GDSC2 0.7939 6.1992 -1.7733 17.7045
SNU-449 GDSC1; GDSC2 1.112 5.4296 -1.1222 12.9983
JHH-6 GDSC1; GDSC2 1.2886 6.8054 -1.6659 15.6375
Huh-7 GDSC1; GDSC2 3.1412 12.6064 -3.1299 18.0157
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-427 GDSC1; GDSC2 -4.9976 -1.0497 -5.1209 58.9354
NCI-H524 GDSC1; GDSC2 -2.8383 0.4408 -3.0505 39.3754
LK-2 GDSC1; GDSC2 -2.8301 1.1745 -3.2288 39.9242
VMRC-LCD GDSC1; GDSC2 -2.8222 0.3016 -3.0034 39.1059
IST-SL1 GDSC1; GDSC2 -2.8075 0.256 -2.9783 38.924
SK-MES-1 GDSC1; GDSC2 -2.7883 4.1512 -4.2781 42.1709
EPLC-272H GDSC1; GDSC2 -2.7562 2.4689 -3.5769 40.4737
NCI-H2171 GDSC2 -2.7269 -1.5274 -2.7281 37.4056
NCI-H460 GDSC1; GDSC2 -2.651 2.3851 -3.4331 39.4765
NCI-H2795 GDSC1; GDSC2 -2.644 4.5014 -4.2768 41.4119
NCI-H1755 GDSC1; GDSC2 -2.5955 2.7117 -3.4953 39.3381
COR-L311 GDSC2 -2.5767 -0.8971 -2.5908 35.9615
NCI-H1703 GDSC1; GDSC2 -2.5757 2.6308 -3.4435 39.0813
NCI-H292 GDSC1; GDSC2 -2.5544 1.5369 -3.0379 37.6637
NCI-H2731 GDSC1; GDSC2 -2.2881 5.7775 -4.4795 40.0716
A-549 GDSC1; GDSC2 -2.2382 1.5541 -2.6995 34.6163
NCI-H2373 GDSC1; GDSC2 -2.1344 10.0564 -6.3472 42.2492
NCI-H1048 GDSC1; GDSC2 -2.0062 2.9116 -2.9464 34.3961
NCI-H1963 GDSC1; GDSC2 -2.0058 0.4059 -2.1393 30.8341
HCC44 GDSC1; GDSC2 -1.9474 1.6465 -2.4138 31.8606
SK-LU-1 GDSC1 -1.9155 6.2457 -4.3236 43.3688
NCI-H209 GDSC1; GDSC2 -1.9083 6.7096 -4.5333 38.4943
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 -1.9059 1.7233 -2.3946 31.5643
NCI-H1944 GDSC1; GDSC2 -1.8754 3.6729 -3.1253 34.4095
NCI-H1341 GDSC1; GDSC2 -1.8234 2.3339 -2.5261 31.7534
EMC-BAC-2 GDSC1; GDSC2 -1.8175 3.9029 -3.1646 34.2712
LOU-NH91 GDSC1; GDSC2 -1.7652 6.09 -4.1025 36.8659
NCI-H520 GDSC1; GDSC2 -1.6583 4.5986 -3.3104 34.0357
NCI-H720 GDSC1; GDSC2 -1.5648 1.9903 -2.1206 28.5983
PC-14 GDSC1; GDSC2 -1.5628 1.5033 -1.9488 27.7189
NCI-H847 GDSC1; GDSC2 -1.549 1.9661 -2.0947 28.3946
SBC-1 GDSC1; GDSC2 -1.4762 1.6902 -1.918 27.1554
NCI-H1155 GDSC1; GDSC2 -1.459 2.0391 -2.0248 27.6236
LXF 289 GDSC1; GDSC2 -1.3491 3.2631 -2.4043 28.9744
NCI-H2227 GDSC1; GDSC2 -1.3257 1.8799 -1.823 25.9679
LB647-SCLC GDSC1; GDSC2 -1.2729 1.3713 -1.5909 24.4892
LC-2/ad GDSC1; GDSC2 -1.1996 3.9392 -2.5493 28.976
NCI-H290 GDSC1; GDSC2 -1.1873 4.7875 -2.9252 30.5205
HCC33 GDSC2 -1.1858 1.3984 -1.505 23.6289
LCLC-97TM1 GDSC1; GDSC2 -1.1422 6.7799 -3.8243 33.4887
NCI-H1734 GDSC1; GDSC2 -1.1294 3.9616 -2.4885 28.397
HOP-62 GDSC1; GDSC2 -1.127 3.4764 -2.2689 27.352
Lu-99A GDSC1; GDSC2 -1.1036 5.8696 -3.3519 31.7797
SBC-5 GDSC1; GDSC2 -0.9712 5.6442 -3.1165 30.3711
Lu-134-A GDSC1; GDSC2 -0.9236 2.1237 -1.4856 22.3647
NCI-H1105 GDSC1; GDSC2 -0.8861 1.654 -1.2679 20.9894
NCI-H2023 GDSC1; GDSC2 -0.882 4.1646 -2.3336 26.6291
NCI-H2110 GDSC1; GDSC2 -0.8722 4.3748 -2.4214 27.0045
NCI-H647 GDSC1; GDSC2 -0.8625 2.7666 -1.6872 23.2178
NCI-H64 GDSC1; GDSC2 -0.8421 1.5148 -1.1712 20.2574
NCI-H2122 GDSC1; GDSC2 -0.8295 4.6503 -2.5083 27.2336
CPC-N GDSC1; GDSC2 -0.8238 2.5474 -1.5537 22.3196
HCC15 GDSC1; GDSC2 -0.7518 3.1013 -1.7196 22.9349
NCI-H1975 GDSC1; GDSC2 -0.7275 3.1816 -1.7307 22.8963
NCI-H3122 GDSC1; GDSC2 -0.6639 2.6835 -1.4461 21.0548
LC-1/sq GDSC1; GDSC2 -0.632 3.7758 -1.9054 23.4504
NCI-H510A GDSC1; GDSC2 -0.6266 2.7906 -1.4544 20.9495
NCI-H1876 GDSC1; GDSC2 -0.6134 1.3703 -0.8741 17.592
HCC827 GDSC1; GDSC2 -0.607 2.3246 -1.2339 19.6127
NCI-H211 GDSC1; GDSC2 -0.5937 1.6929 -0.9677 18.0341
UMC-11 GDSC1; GDSC2 -0.5916 6.0636 -2.9557 28.2344
NCI-H1694 GDSC1; GDSC2 -0.5841 3.6469 -1.7982 22.6857
RERF-LC-MS GDSC1; GDSC2 -0.5725 3.8349 -1.8739 23.0469
Lu-135 GDSC1; GDSC2 -0.5605 1.6459 -0.9146 17.5898
COR-L321 GDSC1; GDSC2 -0.4945 4.3281 -2.0293 23.5587
COR-L279 GDSC1; GDSC2 -0.4718 1.6533 -0.8222 16.6848
NCI-H526 GDSC1; GDSC2 -0.452 6.4113 -2.994 27.8623
NCI-H2030 GDSC1; GDSC2 -0.4054 7.9614 -3.7116 30.3485
NCI-H446 GDSC1; GDSC2 -0.3965 3.8765 -1.7203 21.5289
SBC-3 GDSC1; GDSC2 -0.2855 3.6136 -1.488 19.8036
HOP-92 GDSC1; GDSC2 -0.2688 5.4732 -2.3655 24.3843
NCI-H69 GDSC1; GDSC2 -0.2578 4.2235 -1.7509 21.1713
NCI-H1792 GDSC1; GDSC2 -0.2122 3.1999 -1.2222 17.9864
RERF-LC-KJ GDSC1; GDSC2 -0.2008 3.75 -1.47 19.3824
NCI-H2081 GDSC1; GDSC2 -0.185 3.7539 -1.4566 19.2463
PaCa-3 GDSC1; GDSC2 -0.1821 6.2882 -2.684 25.5452
NCI-H1437 GDSC1; GDSC2 -0.1524 3.3579 -1.2375 17.8518
CAL-12T GDSC1; GDSC2 -0.1433 2.809 -0.9729 16.2492
NCI-H1573 GDSC1; GDSC2 -0.0738 4.8272 -1.8686 21.1337
NCI-H810 GDSC1; GDSC2 -0.0328 6.5877 -2.6952 25.0619
NCI-H1581 GDSC1; GDSC2 -0.0036 4.3947 -1.5923 19.3574
NCI-H250 GDSC2 0.0317 4.0432 -1.3885 18.0628
COR-L32 GDSC2 0.0371 2.6408 -0.7156 14.0234
NCI-H650 GDSC1; GDSC2 0.0503 8.9276 -3.7806 29.0122
NCI-H1299 GDSC1; GDSC2 0.1018 5.5794 -2.0755 21.6012
EKVX GDSC1; GDSC2 0.1322 10.5623 -4.5223 31.0329
NCI-H841 GDSC1; GDSC2 0.1367 7.7198 -3.104 26.2144
NCI-H727 GDSC1; GDSC2 0.1851 7.6184 -3.0106 25.6681
IST-SL2 GDSC1; GDSC2 0.2134 7.604 -2.9784 25.4384
EMC-BAC-1 GDSC1; GDSC2 0.2245 4.5106 -1.4372 17.6691
NCI-H838 GDSC1; GDSC2 0.3642 11.2608 -4.6694 30.728
COR-L23 GDSC1; GDSC2 0.4007 10.0403 -4.0288 28.7049
HCC78 GDSC1; GDSC2 0.4619 8.0003 -2.9581 24.5322
NCI-H2291 GDSC1; GDSC2 0.4661 5.5173 -1.7177 18.4468
SW1271 GDSC1; GDSC2 0.4671 6.2348 -2.0737 20.3532
NCI-H1781 GDSC1; GDSC2 0.4907 4.7719 -1.3255 16.123
NCI-H2369 GDSC1; GDSC2 0.4996 14.0082 -5.9257 33.337
SW1573 GDSC1; GDSC2 0.526 4.7301 -1.2734 15.7003
NCI-H187 GDSC1 0.5381 5.2584 -1.5254 20.8633
NCI-H1666 GDSC1; GDSC2 0.5393 3.7575 -0.7793 12.658
NCI-H3255 GDSC1; GDSC2 0.5438 6.9421 -2.3593 21.5388
NCI-H2085 GDSC1; GDSC2 0.5627 4.5186 -1.1358 14.7594
NCI-H2405 GDSC1; GDSC2 0.586 4.84 -1.275 15.5155
NCI-H1623 GDSC1; GDSC2 0.5889 3.4021 -0.5588 11.1259
SHP-77 GDSC1; GDSC2 0.6126 5.974 -1.8168 18.5151
LCLC-103H GDSC1; GDSC2 0.691 7.8055 -2.6636 22.5038
NCI-H2170 GDSC1; GDSC2 0.7189 7.1135 -2.294 20.6581
Calu-3 GDSC1; GDSC2 0.7431 3.1305 -0.2862 8.9212
NCI-H1568 GDSC1; GDSC2 0.7604 10.8527 -4.1274 27.9292
NCI-H2810 GDSC1; GDSC2 0.7806 3.8178 -0.5957 10.7476
NCI-H23 GDSC1; GDSC2 0.7864 3.4269 -0.3958 9.4749
DMS 273 GDSC1; GDSC2 0.8257 5.786 -1.5398 16.3003
BEN GDSC1; GDSC2 0.8422 7.2089 -2.2369 19.9887
NCI-H1838 GDSC1; GDSC2 0.8993 9.4719 -3.3202 24.6412
NCI-H2009 GDSC1; GDSC2 0.9126 9.5414 -3.3437 24.6933
NCI-H1770 GDSC1; GDSC2 0.9728 5.0494 -1.0474 12.9549
NCI-H1355 GDSC1; GDSC2 1.0185 6.5148 -1.7421 16.8479
COR-L303 GDSC2 1.039 5.787 -1.3611 14.6255
DMS 114 GDSC1; GDSC2 1.0416 5.1811 -1.056 12.8043
NCI-H2591 GDSC1; GDSC2 1.0648 9.3733 -3.1328 23.3944
COR-L95 GDSC1; GDSC2 1.1015 5.46 -1.146 13.1713
EBC-1 GDSC1; GDSC2 1.1164 7.944 -2.3755 19.8432
NCI-H2803 GDSC1; GDSC2 1.1542 6.3633 -1.5542 15.3985
NCI-H1650 GDSC1; GDSC2 1.195 4.0305 -0.356 8.0303
NCI-H1436 GDSC1; GDSC2 1.1989 4.2916 -0.4831 8.8173
NCI-H2461 GDSC1; GDSC2 1.1992 5.3269 -0.9998 12.0101
NCI-H1869 GDSC1 1.2238 3.4702 -0.0539 7.5322
NCI-H2066 GDSC1; GDSC2 1.2769 3.3845 0.0299 5.3824
NCI-H2087 GDSC1; GDSC2 1.287 3.6844 -0.1112 6.2433
NCI-H1836 GDSC1; GDSC2 1.2949 4.649 -0.585 9.1916
NCI-H1993 GDSC1; GDSC2 1.4027 3.5049 0.0653 4.8453
ChaGo-K-1 GDSC1; GDSC2 1.407 3.2638 0.1868 4.0796
COR-L105 GDSC1; GDSC2 1.4692 4.9763 -0.6119 8.8975
NCI-H1304 GDSC1 1.5048 3.2946 0.2413 4.3837
DMS 79 GDSC1; GDSC2 1.5308 3.8148 0.0067 4.9032
NCI-H146 GDSC1; GDSC2 1.5599 6.405 -1.2513 12.5206
DMS 53 GDSC1; GDSC2 1.583 4.0476 -0.0695 5.2522
NCI-H1651 GDSC1; GDSC2 1.5963 7.761 -1.8973 16.0373
NCI-H2342 GDSC1; GDSC2 1.612 4.5092 -0.2744 6.4497
NCI-H661 GDSC1; GDSC2 1.639 4.6498 -0.3236 6.6897
Lu-165 GDSC1; GDSC2 1.6559 3.8992 0.0539 4.3303
NCI-H2141 GDSC1; GDSC2 1.7146 7.4963 -1.6736 14.5084
NCI-H345 GDSC1; GDSC2 1.7364 6.4371 -1.1319 11.3588
KNS-62 GDSC1; GDSC2 1.7754 5.7831 -0.7801 9.1563
ABC-1 GDSC1; GDSC2 1.7861 4.7317 -0.2583 5.9465
COLO 668 GDSC1; GDSC2 1.798 4.4421 -0.1099 5.0166
NCI-H2029 GDSC1; GDSC2 1.8126 6.1453 -0.9309 9.9728
NCI-H322M GDSC1; GDSC2 1.8373 4.3816 -0.0542 4.5961
Calu-6 GDSC1; GDSC2 1.8661 11.3553 -3.4747 22.5191
NCI-H2818 GDSC1; GDSC2 1.8764 10.2396 -2.9112 20.179
NCI-H2444 GDSC1; GDSC2 1.8799 7.0928 -1.3477 12.2492
NCI-H1915 GDSC1; GDSC2 1.9282 14.6253 -5.0554 27.5283
NCI-H522 GDSC2 1.9565 9.1984 -2.3319 17.2913
NCI-H748 GDSC2 1.9752 5.1466 -0.3276 5.9502
COR-L88 GDSC1; GDSC2 2.0157 8.3702 -1.8766 14.8212
NCI-H2869 GDSC1; GDSC2 2.0294 7.2532 -1.3157 11.6937
NCI-H740 GDSC2 2.0422 4.8953 -0.1626 4.8223
NCI-H835 GDSC1; GDSC2 2.065 6.2929 -0.82 8.7085
NCI-H1688 GDSC1; GDSC2 2.0855 8.2756 -1.7776 14.1172
Lu-139 GDSC1; GDSC2 2.0857 5.6133 -0.4766 6.6075
NCI-H2228 GDSC1; GDSC2 2.0932 8.7541 -2.0079 15.3108
Ms-1 GDSC1; GDSC2 2.1031 4.8676 -0.1099 4.3912
NCI-H1092 GDSC1; GDSC2 2.1647 7.0581 -1.1218 10.2525
NCI-H2196 GDSC2 2.1723 4.7571 -0.0147 3.7083
NCI-H1793 GDSC1; GDSC2 2.1875 10.5103 -2.8054 18.9043
NCI-H513 GDSC1; GDSC2 2.1959 4.391 0.167 2.6463
NCI-H226 GDSC1; GDSC2 2.2144 9.9995 -2.5321 17.5872
NCI-H2347 GDSC1; GDSC2 2.2623 11.3619 -3.1702 20.2792
NCI-H82 GDSC1; GDSC2 2.3027 12.2485 -3.5789 21.7972
HCC366 GDSC1; GDSC2 2.3547 5.5796 -0.2833 4.9213
NCI-H1435 GDSC1; GDSC2 2.3636 3.937 0.4522 0.9977
NCI-H358 GDSC1; GDSC2 2.3693 11.4512 -3.1329 19.8569
NCI-H1648 GDSC1; GDSC2 2.3733 9.7673 -2.2984 16.072
NCI-H2804 GDSC1; GDSC2 2.3937 9.6565 -2.2288 15.6799
NCI-H1563 GDSC1; GDSC2 2.4678 9.9463 -2.3167 15.9308
NCI-H2135 GDSC1; GDSC2 2.5092 4.2744 0.384 1.1463
NCI-H2722 GDSC1; GDSC2 2.7942 10.3445 -2.2745 14.9542
IA-LM GDSC1; GDSC2 2.7959 12.6078 -3.3836 19.8426
NCI-H596 GDSC1; GDSC2 2.8119 13.8924 -4.0055 22.1239
NCI-H1693 GDSC1; GDSC2 2.8412 5.7816 -0.0868 3.023
NCI-H2172 GDSC1; GDSC2 2.8529 5.6556 -0.0253 2.6897
RERF-LC-Sq1 GDSC1; GDSC2 2.8817 10.1248 -2.1052 13.9201
NCI-H196 GDSC1; GDSC2 3.2967 12.4101 -2.9228 16.7915
Lu-65 GDSC1; GDSC2 3.4227 5.1466 0.4385 0.351
NCI-H2595 GDSC1; GDSC2 3.6123 5.8487 0.2561 0.7558
NCI-H441 GDSC1; GDSC2 5.2594 16.4746 -3.5406 15.4046
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 2.4408 4.7719 0.1363 2.4362
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
T.T GDSC1; GDSC2 -1.7809 6.2432 -4.1896 37.1531
TE-11 GDSC1; GDSC2 -1.3454 1.7555 -1.7994 25.9329
TE-4 GDSC1; GDSC2 -1.3144 3.3255 -2.3954 28.7773
KYSE-140 GDSC1; GDSC2 -1.2422 4.3328 -2.7707 30.1227
EC-GI-10 GDSC1; GDSC2 -1.1804 3.9925 -2.554 28.9137
TE-9 GDSC1; GDSC2 -0.8745 7.3176 -3.8306 32.4643
KYSE-150 GDSC1; GDSC2 -0.8499 3.2545 -1.8876 24.243
OE21 GDSC1; GDSC2 -0.7335 8.2121 -4.1361 32.8559
TE-1 GDSC1; GDSC2 -0.7328 6.1568 -3.1343 29.4918
KYSE-270 GDSC1; GDSC2 -0.6198 4.8836 -2.4148 25.9589
TE-8 GDSC1; GDSC2 -0.5154 2.7509 -1.323 19.7523
KYSE-410 GDSC1; GDSC2 -0.2156 4.6322 -1.9073 21.86
TE-15 GDSC1; GDSC2 0.4717 6.3175 -2.1109 20.5303
KYSE-520 GDSC1; GDSC2 0.7131 5.6975 -1.592 16.9474
OE33 GDSC1; GDSC2 0.8432 5.1799 -1.222 14.3937
TE-10 GDSC1; GDSC2 1.0215 7.2443 -2.1043 18.768
OE19 GDSC1; GDSC2 1.1229 6.3179 -1.5572 15.5066
KYSE-70 GDSC1; GDSC2 1.192 3.5546 -0.121 6.558
KYSE-450 GDSC1; GDSC2 1.203 10.5715 -3.6177 24.8816
TE-5 GDSC1; GDSC2 1.5371 6.9233 -1.5268 14.1665
TE-6 GDSC1; GDSC2 1.561 4.941 -0.5248 8.1245
KYSE-510 GDSC1; GDSC2 2.0955 6.8964 -1.0926 10.2453
KYSE-180 GDSC1; GDSC2 2.2161 8.7015 -1.8902 14.3898
COLO 680N GDSC1; GDSC2 3.2131 11.6768 -2.6254 15.6593
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TOV-21G GDSC1; GDSC2 -3.8386 7.8319 -6.9732 49.3685
A2780 GDSC1; GDSC2 -3.3383 2.2283 -4.1189 45.1334
DOV13 GDSC1; GDSC2 -3.0714 4.3645 -4.6632 44.2898
Caov-3 GDSC2 -2.5359 0.248 -2.6826 36.161
ES-2 GDSC1; GDSC2 -2.3241 4.146 -3.793 38.6912
OVTOKO GDSC1; GDSC2 -1.7871 7.0757 -4.5874 38.0999
TYK-nu GDSC1; GDSC2 -1.6554 6.6618 -4.2635 36.8006
TOV-112D GDSC1; GDSC2 -1.5296 3.9407 -2.8857 31.8742
JHOS-2 GDSC1; GDSC2 -1.4394 5.5971 -3.5512 33.8643
OAW42 GDSC1 -1.3648 2.7728 -2.2139 34.3082
OVCAR-5 GDSC1; GDSC2 -0.7948 2.2864 -1.4149 21.422
SK-OV-3 GDSC1; GDSC2 -0.5794 8.1097 -3.9439 31.7219
OV-90 GDSC1; GDSC2 -0.1185 4.2637 -1.6373 20.0265
OVK18 GDSC1; GDSC2 -0.0803 2.9055 -0.9548 15.9033
OVCAR-8 GDSC1; GDSC2 -0.0656 2.9162 -0.9453 15.7911
JHOS-4 GDSC1; GDSC2 0.4121 6.6275 -2.3176 21.7663
OVCAR-3 GDSC1; GDSC2 0.4316 5.3091 -1.6448 18.1535
EFO-27 GDSC1; GDSC2 0.447 8.125 -3.0332 24.8951
IGROV-1 GDSC1; GDSC2 0.602 11.2292 -4.4499 29.3916
OC 314 GDSC1; GDSC2 0.8064 9.2572 -3.291 24.808
OVISE GDSC1; GDSC2 0.8514 9.664 -3.4564 25.3112
OV56 GDSC1; GDSC2 1.1639 7.7688 -2.2488 19.078
FU-OV-1 GDSC1; GDSC2 1.2062 2.9703 0.181 4.6161
Caov-4 GDSC1; GDSC2 1.8483 6.1455 -0.9046 9.7279
OVCAR-4 GDSC1; GDSC2 1.8937 10.5142 -3.0343 20.6623
RMG-I GDSC1; GDSC2 2.1012 9.686 -2.4629 17.5488
OAW28 GDSC1; GDSC2 2.2529 10.2151 -2.6096 17.8513
OVKATE GDSC1; GDSC2 2.3515 6.1264 -0.5433 6.446
Kuramochi GDSC1; GDSC2 3.1995 13.5239 -3.5369 19.5129
EFO-21 GDSC1; GDSC2 5.1396 17.5347 -4.1239 17.7317
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PSN1 GDSC1; GDSC2 -1.7717 0.4506 -1.8945 28.4409
Panc 03.27 GDSC1; GDSC2 -1.3372 1.4483 -1.6857 25.2915
KP-4 GDSC1; GDSC2 -1.051 1.9118 -1.5399 23.2178
PaTu 8988t GDSC1; GDSC2 -0.8221 3.2108 -1.84 23.8747
SUIT-2 GDSC1; GDSC2 -0.7308 6.6264 -3.3598 30.3283
Hs 766T GDSC1; GDSC2 -0.6488 4.9461 -2.4726 26.3447
SW1990 GDSC1; GDSC2 -0.5423 2.545 -1.2606 19.5016
HPAC GDSC1; GDSC2 -0.3648 3.3888 -1.461 19.9526
SU.86.86 GDSC1; GDSC2 -0.115 3.4938 -1.2653 17.8761
HuP-T3 GDSC1; GDSC2 -0.0375 4.2388 -1.5485 19.2312
MIA PaCa-2 GDSC1; GDSC2 0.0546 4.3446 -1.5134 18.7012
PaTu 8902 GDSC1; GDSC2 0.2492 4.1863 -1.2552 16.5181
Panc 02.03 GDSC1; GDSC2 0.3106 4.2015 -1.2062 16.0168
PL4 GDSC1; GDSC2 0.5871 4.4978 -1.1039 14.4888
HPAF-II GDSC1 0.5977 5.0353 -1.362 19.5585
HuP-T4 GDSC1; GDSC2 0.6338 4.2357 -0.9323 13.2954
Panc 10.05 GDSC1; GDSC2 0.6942 8.6171 -3.0663 24.2459
Capan-1 GDSC1; GDSC2 0.7269 5.0786 -1.2711 15.0454
KP-2 GDSC1; GDSC2 0.917 3.5064 -0.323 8.618
BxPC-3 GDSC1; GDSC2 1.0914 10.8135 -3.8308 25.9675
QGP-1 GDSC1; GDSC2 1.1849 5.6236 -1.1595 13.012
Panc 08.13 GDSC1; GDSC2 1.3671 3.5794 0.002 5.3282
AsPC-1 GDSC1; GDSC2 1.3743 5.4709 -0.9317 11.112
Panc 04.03 GDSC1; GDSC2 1.471 3.8002 -0.0296 5.2702
MZ-PC-1 GDSC1; GDSC2 1.5393 4.4125 -0.2803 6.6624
KP-3 GDSC1; GDSC2 1.592 9.6767 -2.8554 20.7049
KP-1N GDSC1; GDSC2 1.7843 4.145 0.0233 4.2405
CFPAC-1 GDSC1; GDSC2 2.1434 8.0016 -1.5997 13.0074
Capan-2 GDSC1 2.6656 9.897 -2.1483 17.283
DAN-G GDSC1; GDSC2 2.6924 11.4989 -2.9145 18.1406
YAPC GDSC1; GDSC2 2.8899 11.0898 -2.5698 16.1332
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1; GDSC2 -0.7463 8.5057 -4.2918 33.3419
MSTO-211H GDSC1; GDSC2 -0.6441 3.8196 -1.9377 23.6692
NCI-H2052 GDSC1; GDSC2 -0.563 4.8075 -2.3237 25.3007
NCI-H28 GDSC1; GDSC2 0.5309 10.3017 -4.0473 28.362
NCI-H2452 GDSC1; GDSC2 0.7517 7.5866 -2.5024 21.5638
IST-Mes1 GDSC1; GDSC2 1.1346 3.3387 -0.0592 6.3244
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2 -1.5502 1.6511 -1.9847 27.844
VCaP GDSC1; GDSC2 -0.1177 6.7929 -2.8736 26.141
DU145 GDSC1; GDSC2 0.6173 3.7275 -0.6945 11.8796
22Rv1 GDSC1; GDSC2 1.0303 8.537 -2.7433 21.8213
PC-3 GDSC1; GDSC2 1.2792 4.6877 -0.6167 9.4315
NCI-H660 GDSC2 1.3619 4.4792 -0.448 8.1581
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 3.1899 13.1648 -3.3679 18.8737
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IPC-298 GDSC1; GDSC2 -5.8884 3.5862 -7.3541 59.8481
CHL-1 GDSC1; GDSC2 -5.126 1.1731 -5.7336 57.9886
IGR-37 GDSC1; GDSC2 -4.3386 0.036 -4.5941 53.03
M14 GDSC1 -4.3022 1.6814 -4.986 60.069
SK-MEL-2 GDSC1; GDSC2 -4.0109 2.417 -4.9119 50.1969
G-mel GDSC1; GDSC2 -3.4118 0.676 -3.7303 45.0189
LOX-IMVI GDSC1; GDSC2 -2.4365 2.2491 -3.1528 37.4008
SH-4 GDSC1; GDSC2 -2.2787 5.3076 -4.2574 39.5667
A-375 GDSC1; GDSC2 -2.1388 1.4393 -2.5548 33.4734
RPMI-7951 GDSC1; GDSC2 -2.1214 2.2923 -2.8298 34.5326
SK-MEL-3 GDSC1; GDSC2 -1.9621 5.3576 -3.9607 37.3808
A101D GDSC1; GDSC2 -1.7416 7.0038 -4.5091 37.7384
COLO 800 GDSC1; GDSC2 -1.6634 7.2496 -4.55 37.5079
COLO 679 GDSC1; GDSC2 -1.5632 1.5919 -1.9787 27.874
Mel Ho GDSC1; GDSC2 -1.4803 10.1613 -5.7824 39.1555
GAK GDSC1; GDSC2 -1.4727 3.8484 -2.7867 31.2133
RVH-421 GDSC1; GDSC2 -1.4446 4.054 -2.8493 31.3422
MMAc-SF GDSC1; GDSC2 -1.4249 5.5386 -3.5096 33.667
WT2-iPS GDSC1; GDSC2 -1.4223 2.3082 -2.0882 27.7753
MZ-MEL-2 GDSC1; GDSC2 -1.2482 8.6467 -4.8275 36.51
SK-MEL-28 GDSC1; GDSC2 -1.1905 3.9108 -2.5273 28.8372
SK-MEL-5 GDSC1; GDSC2 -1.1729 5.5453 -3.2656 31.7577
WM35 GDSC1; GDSC2 -1.1266 1.8575 -1.6008 23.8841
WM278 GDSC1; GDSC2 -1.1153 6.6906 -3.7556 33.1692
WM793 GDSC1; GDSC2 -1.0376 4.5355 -2.6598 28.7727
A-431 GDSC1; GDSC2 -0.9582 6.6415 -3.5822 31.9868
451Lu GDSC1; GDSC2 -0.8468 4.9873 -2.6841 28.0917
Hs 938.T GDSC1; GDSC2 -0.7057 2.3997 -1.3685 20.7877
CP50-MEL-B GDSC1; GDSC2 -0.6744 3.7758 -1.9476 23.8427
HT-144 GDSC1; GDSC2 -0.4532 6.9248 -3.2462 28.8601
DJM-1 GDSC1; GDSC2 -0.4194 3.4469 -1.5421 20.6238
SK-MEL-30 GDSC1; GDSC2 -0.4127 12.0925 -5.7634 35.6395
Mel JuSo GDSC1; GDSC2 -0.3848 4.0648 -1.798 21.9083
IST-MEL1 GDSC1; GDSC2 -0.353 9.3282 -4.3392 32.0991
A2058 GDSC1; GDSC2 -0.2867 2.6366 -1.0391 17.1947
MeWo GDSC1; GDSC2 -0.2743 7.221 -3.2272 28.1358
SK-MEL-24 GDSC1; GDSC2 -0.2147 7.4855 -3.3034 28.214
IGR-1 GDSC1; GDSC2 -0.1814 4.6671 -1.8919 21.6514
UACC-62 GDSC1; GDSC2 -0.168 3.271 -1.2119 17.7595
HMV-II GDSC1; GDSC2 0.1557 7.9707 -3.2118 26.5806
SK-MEL-1 GDSC1; GDSC2 0.7519 6.8582 -2.1384 19.7713
COLO 792 GDSC1; GDSC2 0.7768 17.8166 -7.595 35.5719
LB2518-MEL GDSC1; GDSC2 0.8172 10.989 -4.1476 27.8267
COLO 783 GDSC1; GDSC2 0.9545 5.3358 -1.2059 13.9619
G-361 GDSC1; GDSC2 0.9826 10.142 -3.5855 25.4032
SK-MEL-31 GDSC1; GDSC2 1.1644 7.7093 -2.2187 18.9252
WM115 GDSC1; GDSC2 1.1758 7.8912 -2.3002 19.2982
A-388 GDSC1; GDSC2 1.3372 5.3634 -0.9074 11.0651
UACC-257 GDSC1; GDSC2 1.3704 6.1336 -1.265 13.1157
COLO 829 GDSC1; GDSC2 1.4476 11.3089 -3.7863 24.8066
WM1552C GDSC1; GDSC2 1.5463 9.0632 -2.5858 19.6104
LB373-MEL-D GDSC1; GDSC2 1.8787 6.7168 -1.1632 11.1842
VMRC-MELG GDSC1; GDSC2 1.8857 3.7651 0.2673 2.6082
CP66-MEL GDSC1; GDSC2 1.9004 5.8389 -0.7163 8.4703
Hs 940.T GDSC1; GDSC2 1.9214 8.9599 -2.2405 16.9329
MZ-MEL-7 GDSC1; GDSC2 3.5011 5.1796 0.4562 0.2849
EquiPSC Line K2 GDSC1; GDSC2 -0.0092 7.8646 -3.3058 27.5059
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -2.7449 1.0147 -3.0909 38.9569
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1080 GDSC1; GDSC2 -3.5806 2.5751 -4.503 47.135
Hs 633.T GDSC1; GDSC2 -3.2464 4.1427 -4.7542 45.36
SW982 GDSC1; GDSC2 -3.0605 3.8825 -4.452 43.9406
A-204 GDSC1; GDSC2 -2.6951 4.2568 -4.2255 41.5794
EW-8 GDSC1; GDSC2 -2.1881 1.1053 -2.5086 33.5244
STS-0421 GDSC1; GDSC2 -1.8658 3.0836 -2.8681 33.3956
Rh30 GDSC1; GDSC2 -1.814 2.0562 -2.4126 31.1941
G-402 GDSC1; GDSC2 -1.6663 4.8742 -3.4433 34.5164
MFH-ino GDSC1; GDSC2 -1.6457 2.8862 -2.5557 31.0281
SW872 GDSC1; GDSC2 -1.0307 3.0226 -1.9715 25.445
SK-LMS-1 GDSC1; GDSC2 -0.9075 3.2945 -1.9642 24.8855
RKN GDSC1; GDSC2 -0.6633 4.1076 -2.0907 24.539
MES-SA GDSC1; GDSC2 -0.4216 3.5025 -1.5701 20.7901
KYM-1 GDSC1; GDSC2 -0.4057 5.7946 -2.6502 26.2187
SK-UT-1 GDSC1; GDSC2 -0.3133 9.3375 -4.3082 31.8766
G-401 GDSC1; GDSC2 -0.2998 4.6959 -2.0181 22.7573
VA-ES-BJ GDSC1; GDSC2 -0.2575 7.8078 -3.5014 29.0951
GCT GDSC1; GDSC2 -0.0085 4.642 -1.7172 20.0728
Rh41 GDSC1; GDSC2 0.5506 5.9731 -1.8704 19.0055
SW684 GDSC1; GDSC2 0.9911 8.5088 -2.7618 22.0224
TE 441.T GDSC2 1.2588 6.07 -1.3227 13.7657
Rh18 GDSC1 2.1723 16.904 -5.9974 32.0753
RD GDSC1; GDSC2 5.8291 17.5367 -3.6737 14.9152
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC1; GDSC2 -3.7583 -1.5393 -3.7763 47.7827
AGS GDSC1; GDSC2 -3.2877 3.1082 -4.3863 45.1726
HGC-27 GDSC1; GDSC2 -3.02 0.6851 -3.3053 41.3425
ECC10 GDSC1; GDSC2 -2.3445 2.1458 -3.0165 36.4218
OCUM-1 GDSC1; GDSC2 -2.116 4.6084 -3.7802 37.6277
KATO III GDSC1; GDSC2 -1.9529 2.3164 -2.6581 32.9696
RF-48 GDSC1; GDSC2 -1.4375 2.9337 -2.3567 29.1521
SNU-16 GDSC1; GDSC2 -0.9883 2.1875 -1.5795 23.1625
Fu97 GDSC1; GDSC2 -0.6784 7.9169 -3.9405 32.0714
IM95 GDSC1; GDSC2 -0.5589 2.456 -1.2395 19.4479
SNU-1 GDSC1; GDSC2 -0.408 2.4729 -1.0908 17.977
23132/87 GDSC1; GDSC2 -0.1189 9.4924 -4.2113 30.9427
RERF-GC-1B GDSC1; GDSC2 0.1226 8.1109 -3.3107 27.0765
TMK-1 GDSC1; GDSC2 0.1674 5.9708 -2.2093 22.0553
TGBC11TKB GDSC1; GDSC2 0.2601 5.4274 -1.857 19.8989
Hs 746.T GDSC1; GDSC2 0.4259 6.0096 -1.998 20.0936
MKN45 GDSC1; GDSC2 0.8101 4.8242 -1.0725 13.5981
GCIY GDSC1; GDSC2 0.9474 4.5766 -0.8323 11.7138
MKN1 GDSC1; GDSC2 0.9622 5.6543 -1.3587 14.84
ECC12 GDSC2 1.0649 4.4229 -0.6577 10.2866
NUGC-4 GDSC1; GDSC2 1.0702 4.0576 -0.4707 9.1008
NCI-N87 GDSC1 1.2731 4.0488 -0.3032 9.3081
SNU-5 GDSC1; GDSC2 1.2889 3.7184 -0.1266 6.3349
NUGC-3 GDSC1; GDSC2 1.5766 9.9581 -3.0081 21.4085
MKN7 GDSC1; GDSC2 1.7686 8.0654 -1.9144 15.6636
MKN28 GDSC1; GDSC2 1.7735 5.394 -0.5904 8.0073
SK-GT-2 GDSC1; GDSC2 2.0473 5.8979 -0.6405 7.6756
SCH GDSC1; GDSC2 2.7754 13.7655 -3.9703 22.0855
SNG-M GDSC1; GDSC2 -0.4294 5.6662 -2.6101 26.1279
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CGTH-W-1 GDSC1; GDSC2 -3.4636 -1.0525 -3.5005 44.9064
K5 GDSC1; GDSC2 -2.8827 0.8914 -3.2081 40.1808
IHH-4 GDSC1; GDSC2 -2.6802 2.1808 -3.3911 39.5237
TT2609-C02 GDSC1; GDSC2 -2.56 2.5706 -3.4041 38.8789
FTC-133 GDSC1; GDSC2 -2.2653 0.9206 -2.5421 34.0803
HTC-C3 GDSC1; GDSC2 -1.7773 2.4727 -2.5301 31.5463
8505C GDSC1; GDSC2 -1.5641 4.2878 -3.0753 32.7648
TT GDSC1; GDSC2 -0.9933 5.5355 -3.0862 30.3445
ASH-3 GDSC1; GDSC2 -0.9357 1.7824 -1.368 21.7638
CAL-62 GDSC1; GDSC2 -0.8912 2.3535 -1.5438 22.5496
KMH-2 GDSC1; GDSC2 -0.5788 1.3816 -0.8405 17.2515
BHT-101 GDSC1; GDSC2 -0.0519 4.3906 -1.6356 19.7746
B-CPAP GDSC1; GDSC2 0.1666 4.1854 -1.3312 17.252
ML-1 [Human leukemia] GDSC1; GDSC2 0.6154 6.7047 -2.1789 20.4104
8305C GDSC1; GDSC2 1.2563 16.0542 -6.3146 32.1764
WRO GDSC1; GDSC2 2.272 19.4892 -7.2071 31.5714
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-06A GDSC1; GDSC2 -3.4144 0.2794 -3.6417 44.8677
HSC-3 GDSC1; GDSC2 -3.1753 2.9226 -4.1955 44.2266
JHU-011 GDSC1; GDSC2 -2.8648 4.3477 -4.4407 42.8574
BICR 10 GDSC1 -2.7488 0.9048 -3.0656 47.3817
KON GDSC1; GDSC2 -2.6252 3.4514 -3.8179 40.3328
Detroit 562 GDSC1; GDSC2 -2.3196 2.056 -2.9576 36.0708
BICR 78 GDSC1; GDSC2 -2.2496 3.8499 -3.5894 37.7606
PCI-38 GDSC1 -1.9921 2.7576 -2.8702 40.9017
OSC-19 GDSC1; GDSC2 -1.9604 2.8061 -2.8557 33.8151
HSC-4 GDSC1; GDSC2 -1.9057 4.9201 -3.7055 36.4217
DOK GDSC1; GDSC2 -1.8866 5.4289 -3.9175 36.9221
FaDu GDSC1; GDSC2 -1.639 4.0141 -3.0299 32.9382
CAL-27 GDSC1; GDSC2 -1.5329 1.7999 -2.0177 27.9311
HO-1-u-1 GDSC1; GDSC2 -1.3422 4.943 -3.1509 32.0593
HO-1-N-1 GDSC1; GDSC2 -1.2901 2.2344 -1.9187 26.3086
PCI-04B GDSC1; GDSC2 -1.2077 4.7344 -2.9207 30.5897
KOSC-2 GDSC1; GDSC2 -1.1482 5.1115 -3.0375 30.7981
BB30-HNC GDSC1; GDSC2 -0.9412 2.8687 -1.8125 24.2262
JHU-022 GDSC1; GDSC2 -0.9261 3.8741 -2.2442 26.3785
PCI-15A GDSC1; GDSC2 -0.8641 1.8428 -1.3138 21.1503
CAL-33 GDSC1; GDSC2 -0.8435 2.1222 -1.4 21.5448
SAS GDSC1; GDSC2 -0.8209 6.8461 -3.5512 31.3477
BICR 31 GDSC2 -0.2398 1.2716 -0.4359 13.4951
NCI-H3118 GDSC1; GDSC2 -0.209 5.6974 -2.4192 24.4215
BICR 22 GDSC1; GDSC2 -0.1592 4.155 -1.6236 20.099
OSC-20 GDSC1; GDSC2 -0.0609 4.4594 -1.6775 20.0412
SKN-3 GDSC1; GDSC2 0.3226 10.7997 -4.4752 30.3087
JHU-029 GDSC1; GDSC2 0.3768 7.4232 -2.7447 23.8836
SCC-25 GDSC1; GDSC2 0.4318 6.6969 -2.3348 21.7852
SCC-9 GDSC1; GDSC2 0.5153 5.6328 -1.7317 18.363
BB49-HNC GDSC1 0.5972 6.7389 -2.2117 24.5935
SCC-4 GDSC1; GDSC2 0.6453 9.9037 -3.7508 27.0116
HSC-2 GDSC1; GDSC2 0.6967 5.0316 -1.2739 15.1565
Ca9-22 GDSC1; GDSC2 0.7023 4.1806 -0.8447 12.5397
BHY GDSC1; GDSC2 0.8296 7.3781 -2.3322 20.5002
SAT [Human HNSCC] GDSC1; GDSC2 0.8938 8.2143 -2.696 22.0208
PCI-30 GDSC1; GDSC2 1.0317 7.2487 -2.098 18.7053
LB771-HNC GDSC1; GDSC2 1.3914 4.7281 -0.5488 8.7089
PE/CA-PJ15 GDSC1; GDSC2 1.7102 4.294 -0.0993 5.1451
UPCI-SCC-090 GDSC1; GDSC2 2.0582 11.3463 -3.3199 21.4089
SCC-15 GDSC1; GDSC2 2.925 12.0855 -3.0318 18.0979
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 GDSC1; GDSC2 -2.7736 2.0608 -3.4499 40.2358
BFTC-905 GDSC1; GDSC2 -2.2949 1.2058 -2.6541 34.7274
SW1710 GDSC1; GDSC2 -1.4791 4.0326 -2.8749 31.6014
SW780 GDSC1; GDSC2 -0.7016 3.7813 -1.9772 24.1069
647V GDSC1; GDSC2 -0.528 4.9136 -2.3408 25.2473
RT-112 GDSC1; GDSC2 -0.5274 3.4968 -1.6725 21.7745
KU-19-19 GDSC1; GDSC2 -0.5056 5.361 -2.5344 26.0731
CAL-29 GDSC1; GDSC2 0.0479 3.5567 -1.1383 16.5301
639V GDSC1; GDSC2 0.2975 3.6339 -0.9401 14.4573
UM-UC-3 GDSC1; GDSC2 1.0509 4.2131 -0.5643 9.7437
RT-4 GDSC1; GDSC2 1.3133 6.6767 -1.5816 15.0965
J82 GDSC1; GDSC2 1.5452 4.8055 -0.4697 7.8228
T24 GDSC1; GDSC2 1.5585 6.1596 -1.1304 11.8123
TCCSUP GDSC1; GDSC2 1.7435 7.0358 -1.4229 13.0283
HT-1376 GDSC1; GDSC2 1.9748 5.9985 -0.7408 8.4433
HT-1197 GDSC1; GDSC2 2.2355 5.3398 -0.247 4.9376
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1; GDSC2 -2.8951 7.0269 -5.6588 44.5442
TC-YIK GDSC1; GDSC2 -2.235 -0.7001 -2.2485 32.5313
HEY GDSC1; GDSC2 -2.114 1.9681 -2.7046 33.9861
SW962 GDSC1; GDSC2 -1.8796 2.1973 -2.535 32.0702
SKN GDSC1; GDSC2 -1.8003 3.8669 -3.1312 34.0702
SKG-IIIa GDSC1; GDSC2 -1.7273 4.6727 -3.4136 34.6978
NEC8 GDSC1; GDSC2 -1.6611 0.9793 -1.8985 27.927
MS751 GDSC1; GDSC2 -1.5432 2.6353 -2.3458 29.5885
C-4-I GDSC1; GDSC2 -1.4185 3.0507 -2.386 29.2028
OVCA433 GDSC1; GDSC2 -1.1601 4.4176 -2.7273 29.5845
PA-1 GDSC1; GDSC2 -1.1577 4.6724 -2.8424 30.0569
CAL-39 GDSC1; GDSC2 -1.1355 2.6954 -1.9414 25.7418
NT2-D1 GDSC1; GDSC2 -1.0847 4.8533 -2.8542 29.7967
SW954 GDSC1; GDSC2 -0.9932 3.4069 -2.1015 25.9509
BPH-1 GDSC1; GDSC2 -0.6978 2.9888 -1.6146 22.1366
ME-180 GDSC1; GDSC2 -0.4729 10.8602 -5.2056 34.671
Ca Ski GDSC1; GDSC2 -0.3138 7.0684 -3.1883 28.1277
SiSo GDSC1; GDSC2 -0.2967 3.638 -1.5104 19.9738
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 -0.2752 4.5756 -1.9366 22.2374
PWR-1E GDSC1; GDSC2 -0.2479 2.6424 -1.0024 16.8265
PEO1 GDSC1; GDSC2 -0.1938 6.6416 -2.8685 26.3918
SW756 GDSC1; GDSC2 -0.1662 3.0034 -1.0854 17.0053
OVMIU GDSC1; GDSC2 0.0882 4.7547 -1.6825 19.5368
HT-3 GDSC1; GDSC2 0.0903 4.2694 -1.4434 18.1725
DSH1 GDSC1; GDSC2 0.1027 5.0376 -1.8079 20.177
HeLa GDSC1; GDSC2 0.2961 5.3833 -1.8028 19.4826
C-33 A GDSC1; GDSC2 0.5417 5.2866 -1.5363 17.1784
LB831-BLC GDSC1; GDSC2 1.0575 6.4549 -1.6797 16.3863
UWB1.289 GDSC1; GDSC2 1.0974 7.2352 -2.0368 18.192
OVCA420 GDSC1; GDSC2 1.1803 7.7989 -2.2504 19.0373
JHOS-3 GDSC1; GDSC2 1.1895 3.1564 0.0754 5.3258
DoTc2 4510 GDSC1; GDSC2 1.2817 6.9666 -1.7519 16.1315
JAR GDSC1; GDSC2 1.2824 5.2092 -0.8741 11.0119
HEC-1 GDSC1; GDSC2 1.4298 6.9456 -1.6227 14.9996
NCC-IT GDSC2 1.4644 8.3735 -2.3073 18.504
JEG-3 GDSC1; GDSC2 1.7471 5.5902 -0.7062 8.7768
SiHa GDSC1; GDSC2 2.1303 8.7178 -1.9622 14.9802
ACC-OV7 GDSC1; GDSC2 2.3048 9.646 -2.2896 16.1981
OV17R GDSC1; GDSC2 2.4477 11.2617 -2.98 19.016
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5672).
2 Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with ... Blood. 2008 Jun 15;111(12):5663-71.