Details of the Drug

General Information of Drug (ID: DMQ7VDM)

Drug Name

TDI-0033

Synonyms

Gene therapy program (NGF receptor agonist); TDI-0034; TDI-0035; TDI-0036; TDI-0038; TDI-0041; Gene therapy program (NGF receptor agonist), ALS Therapy Development Foundation

Indication

Disease Entry	ICD 11	Status	REF
Motor neurone disease	8B60	Investigative	[1]
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Cross-matching ID

TTD ID: D0Q8ZP

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Low-affinity nerve growth factor receptor (NGFR)	TTEDJN4	TNR16_HUMAN	Agonist	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Motor neurone disease

ICD Disease Classification

8B60

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Low-affinity nerve growth factor receptor (NGFR)	DTT	NGFR	5.08E-01	0.38	0.37

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1888).