Details of the Drug

General Information of Drug (ID: DMQEC6Z)

Drug Name
Melanoma vaccine
Synonyms NA17.A2 peptides, Institut Curie; Vaccine (melanoma), Institut Curie; Melanoma vaccine (NA17.A2/tyrosinase/MART-1, gp100); Melanoma vaccine (NA17.A2/tyrosinase/MART-1, gp100), Institut Curie
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Phase 3 [1]
ATC Code
L03AX12: Melanoma vaccine
L03AX: Other immunostimulants
L03A: IMMUNOSTIMULANTS
L03: IMMUNOSTIMULANTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Vaccine
Cross-matching ID
TTD ID
D0U9MJ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MART-1 melanoma antigen (MLANA) TT362RB MAR1_HUMAN Not Available [2]
Melanocytes lineage-specific antigen GP100 (PMEL) TT8MK59 PMEL_HUMAN Not Available [2]
Tyrosinase (TYR) TTULVH8 TYRO_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

ICD Disease Classification 02 Neoplasm
Disease Class ICD-11: 2C82 Prostate cancer
The Studied Tissue Skin
The Studied Disease Melanoma [ICD-11:2C82]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tyrosinase (TYR) DTT TYR 6.68E-04 2.54 1.15
Melanocytes lineage-specific antigen GP100 (PMEL) DTT PMEL 1.08E-03 1.89 1.06
MART-1 melanoma antigen (MLANA) DTT MLANA 3.29E-02 1.64 0.76
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00036816) Vaccine Therapy in Treating Patients With Melanoma of the Eye. U.S. National Institutes of Health.
2 National Cancer Institute Drug Dictionary (drug id 685201).