Details of the Drug

General Information of Drug (ID: DMQG7ZM)

Drug Name

Belagenpumatucel-L

Synonyms

Lucanix (TN)

Indication

Disease Entry	ICD 11	Status	REF
Non-small-cell lung cancer	2C25.Y	Phase 3	[1]
Small-cell lung cancer	2C25.Y	Phase 3	[1]
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Drug Type

Vaccine

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TGF beta-2 messenger RNA (TGFB2 mRNA)	TTI0KH6	TGFB2_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Non-small-cell lung cancer

ICD Disease Classification

2C25.Y

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
TGF beta-2 messenger RNA (TGFB2 mRNA)	DTT	TGFB2	1.51E-17	-0.53	-0.77

Molecular Expression Atlas (MEA)

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References

1	ClinicalTrials.gov (NCT00676507) Phase III Lucanix Vaccine Therapy in Advanced Non-small Cell Lung Cancer (NSCLC) Following Front-line Chemotherapy. U.S. National Institutes of Health.
2	National Cancer Institute Drug Dictionary (drug id 590662).