General Information of Drug (ID: DMQKNLN)

Drug Name
CX-5461
Synonyms RNA ppolymerase I inhibitor (oral, cancer), Cylene
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C27H27N7O2S
Canonical SMILES
CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)C
InChI
1S/C27H27N7O2S/c1-17-14-29-18(15-28-17)16-30-26(36)23-24(35)19-8-9-22(33-11-5-10-32(2)12-13-33)31-25(19)34-20-6-3-4-7-21(20)37-27(23)34/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3,(H,30,36)
InChIKey
XGPBJCHFROADCK-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
25257557
ChEBI ID
CHEBI:95090
CAS Number
1138549-36-6
UNII
3R4C5YLB9I
DrugBank ID
DB16846
TTD ID
D0B7LU
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 2.9598 8.392 0.5008 22.6023
SK-ES-1 GDSC1 -3.1334 29.0338 -15.224 54.215
EW-7 GDSC1 -2.5357 7.5517 -4.5602 59.5835
ES1 GDSC1 -2.4986 3.6791 -3.1243 63.8615
ES7 GDSC1 -1.1993 2.9071 -1.5003 55.4664
SK-PN-DW GDSC1 -0.4493 2.9291 -0.6885 47.9046
CADO-ES1 GDSC1 -0.2891 4.0086 -0.8175 46.5851
EW-13 GDSC1 0.6107 5.1261 -0.2576 38.3952
ES8 GDSC1 0.7005 5.4981 -0.3157 38.0148
EW-1 GDSC1 0.9514 7.6979 -1.0417 38.752
ES5 GDSC1 1.2281 7.2541 -0.5617 35.7713
ES4 GDSC1 1.839 6.9681 0.17 29.4605
EW-18 GDSC1 2.3423 7.5566 0.3609 26.0478
EW-16 GDSC1 2.3582 9.039 -0.3545 29.4694
U2OS GDSC1 2.3615 6.6777 0.8078 23.3309
EW-3 GDSC1 2.4398 9.023 -0.273 28.7574
EW-11 GDSC1 2.586 8.9771 -0.1194 27.4251
MHH-ES-1 GDSC1 2.5937 9.6693 -0.4563 28.9044
MG-63 GDSC1 2.6041 4.4957 2.0816 13.1519
SJSA-1 GDSC1 2.9391 6.206 1.5704 15.5576
TC-71 GDSC1 2.9432 8.4094 0.4777 22.8032
ES6 GDSC1 3.4042 9.5981 0.2751 22.1536
H-EMC-SS GDSC1 3.6428 9.6802 0.4297 20.419
HOS GDSC1 4.4071 6.7404 2.4391 4.1924
EW-24 GDSC1 4.798 5.994 2.9599 0.465
NOS-1 [Human HNSCC] GDSC1 4.8712 13.7489 -0.6379 21.8419
HuO-3N1 GDSC1 5.1142 9.906 1.405 9.7556
CHSA8926 GDSC1 5.2351 6.7387 2.8602 0.5323
CAL-72 GDSC1 5.4191 6.6539 2.9595 0.1765
G-292 clone A141B1 GDSC1 5.4208 7.9464 2.4678 2.2037
A-673 GDSC1 5.5668 6.8934 2.9299 0.1915
CAL-78 GDSC1 5.8251 10.1729 1.719 6.12
CHSA0108 GDSC1 5.8466 8.3289 2.5124 1.4765
CHSA0011 GDSC1 5.9815 10.5888 1.6225 6.4269
NY GDSC1 6.0385 8.3296 2.5943 0.9586
SaOS-2 GDSC1 6.0453 7.4453 2.9098 0.1162
HuO9 GDSC1 6.1169 8.2299 2.6627 0.6622
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 144 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 -0.1942 3.0685 -0.4439 45.1007
OCI-AML-2 GDSC1 -3.8787 -0.6698 -3.8992 82.073
RS4;11 GDSC1 -3.8591 -2.1427 -3.8592 87.1445
MOLT-4 GDSC1 -3.5208 -2.4932 -3.5208 85.4551
Loucy GDSC1 -3.4603 2.8504 -3.951 70.159
OCI-Ly19 GDSC1 -3.4184 -1.4516 -3.4193 82.152
SR GDSC1 -3.3667 -0.3674 -3.3863 78.5112
CESS GDSC1 -3.3312 0.9746 -3.4563 74.2623
BV-173 GDSC1 -3.212 -2.0188 -3.212 81.6324
Reh GDSC1 -3.199 0.1568 -3.2402 75.9353
697 GDSC1 -3.1913 -1.5516 -3.1915 80.5995
Ku812 GDSC1 -3.1354 0.8645 -3.2356 73.5343
RPMI-8402 GDSC1 -3.1015 -0.3831 -3.1148 76.8963
CCRF-CEM GDSC1 -2.8246 1.7542 -3.029 69.4761
QIMR-WIL GDSC1 -2.7051 0.8087 -2.7758 71.0058
HAL-01 GDSC1 -2.579 -0.0257 -2.5929 72.0063
MY-M12 GDSC1 -2.5479 0.526 -2.5884 70.5275
SUP-B15 GDSC1 -2.3863 -0.6487 -2.3874 71.2338
SU-DHL-5 GDSC1 -2.0921 0.7181 -2.1277 66.289
WIL2 NS GDSC1 -2.0072 0.0179 -2.0127 66.4352
NALM-6 GDSC1 -1.9142 1.2792 -1.9896 63.7725
SIG-M5 GDSC1 -1.8909 1.7208 -2.0207 62.8869
NKM-1 GDSC1 -1.8616 5.2609 -2.9521 58.2887
Namalwa GDSC1 -1.8525 3.7025 -2.4265 59.8504
P30/OHK GDSC1 -1.5845 0.7674 -1.6055 61.1438
OCI-AML-5 GDSC1 -1.5551 6.1674 -2.9673 55.8383
P12-Ichikawa GDSC1 -1.1956 4.1399 -1.8455 54.6582
DND-41 GDSC1 -1.1378 2.9847 -1.452 54.8544
EoL-1 GDSC1 -1.0716 1.4772 -1.1215 55.0104
PF-382 GDSC1 -0.9702 4.387 -1.6823 52.7523
RPMI-8866 GDSC1 -0.7506 2.0556 -0.8492 51.2225
NB4 GDSC1 -0.7156 3.6872 -1.1821 50.6818
HC-1 GDSC1 -0.4747 3.5017 -0.8652 48.3039
HEL GDSC1 -0.4513 2.1377 -0.5409 47.75
GDM-1 GDSC1 -0.3481 4.4164 -1.0186 47.314
CA46 GDSC1 -0.2174 4.783 -1.009 46.2432
ST486 GDSC1 -0.21 9.1556 -2.8697 47.6288
KOPN-8 GDSC1 -0.127 2.8039 -0.3098 44.1664
MOLP-8 GDSC1 -0.0576 7.946 -2.1651 46.3433
OCI-M1 GDSC1 -0.0225 2.8825 -0.2134 42.9756
CTB-1 GDSC1 0.113 8.5081 -2.2496 45.4671
Daudi GDSC1 0.2516 2.4989 0.1577 39.3013
P32/ISH GDSC1 0.2558 2.2278 0.2008 39.0558
Ramos.2G6.4C10 GDSC1 0.4452 2.0556 0.4181 36.5488
A4/Fukuda GDSC1 0.4856 5.8953 -0.7072 40.6194
RPMI-6666 GDSC1 0.5891 6.7321 -0.9649 40.6317
WSU-NHL GDSC1 0.7073 10.1225 -2.4266 42.6928
MV4-11 GDSC1 0.7583 7.0807 -0.9503 39.594
CTV-1 GDSC1 0.7705 6.1664 -0.5296 38.2976
ALL-PO GDSC1 0.7892 7.4981 -1.1103 39.8244
YT GDSC1 0.8082 3.4969 0.5358 33.4696
VL51 GDSC1 0.9316 5.4333 -0.0472 35.5164
SU-DHL-8 GDSC1 0.9718 6.0719 -0.2816 36.2102
MOLM-13 GDSC1 0.9908 10.7383 -2.4532 41.4451
A3/Kawakami GDSC1 1.0612 4.8439 0.3321 32.9536
BL-41 GDSC1 1.0824 2.3679 1.0588 28.5705
RPMI-8226 GDSC1 1.1445 4.2702 0.6432 30.7521
SCC-3 GDSC1 1.2409 3.5857 0.9811 28.1093
LAMA-84 GDSC1 1.2428 8.4196 -1.0974 37.3759
U-698-M GDSC1 1.2857 5.4693 0.3046 31.7597
KE-37 GDSC1 1.3517 6.9502 -0.2981 34.1143
ALL-SIL GDSC1 1.4475 7.2763 -0.3566 33.835
U266B1 GDSC1 1.6033 9.5693 -1.3096 36.2354
MN-60 GDSC1 1.6174 6.8435 0.0134 31.3541
JSC-1 GDSC1 1.6548 11.2114 -2.0661 37.876
KMOE-2 GDSC1 1.7359 6.0476 0.5015 28.2298
SUP-M2 GDSC1 1.7363 7.1599 -0.0207 30.8999
MHH-PREB-1 GDSC1 1.8251 5.473 0.8536 25.6689
KMS-12-BM GDSC1 1.8552 7.3169 0.0188 30.1179
SK-MM-2 GDSC1 1.8779 9.4026 -0.9728 33.9576
BE-13 GDSC1 2.0291 12.2045 -2.2174 36.7126
NU-DUL-1 GDSC1 2.0395 6.4237 0.623 25.9903
Sc-1 GDSC1 2.0611 5.3342 1.1541 22.5013
VAL GDSC1 2.0731 9.9547 -1.0652 33.4001
HH [Human lymphoma] GDSC1 2.1594 7.5886 0.1752 27.8779
SUP-HD1 GDSC1 2.1709 5.2399 1.307 20.9042
SUP-T1 GDSC1 2.2288 8.0986 -0.0096 28.4737
JVM-2 GDSC1 2.29 8.8819 -0.3388 29.7015
KCL-22 GDSC1 2.3431 6.6073 0.8247 23.3101
OPM-2 GDSC1 2.4277 7.3352 0.5483 24.5999
SU-DHL-16 GDSC1 2.5459 6.039 1.2914 19.2621
MEG-01 GDSC1 2.6789 7.2511 0.819 21.8455
DB GDSC1 2.7454 10.3168 -0.6454 29.0712
SU-DHL-1 GDSC1 2.7491 3.7113 2.5715 8.8094
GR-ST GDSC1 2.7757 5.9469 1.5501 16.3901
JURL-MK1 GDSC1 2.8995 6.4786 1.3998 16.9692
MLMA GDSC1 2.9002 4.0161 2.5975 7.8687
SU-DHL-4 GDSC1 2.9678 7.3074 1.0482 19.1409
Farage GDSC1 2.9764 6.9854 1.2161 17.958
LC4-1 GDSC1 3.0677 7.0309 1.2732 17.1913
KG-1 GDSC1 3.1875 9.1005 0.3422 22.6034
Karpas-45 GDSC1 3.2071 10.5883 -0.3848 26.1752
ATN-1 GDSC1 3.2343 4.9206 2.4702 7.4414
ARH-77 GDSC1 3.2829 7.4846 1.2305 16.6557
Raji GDSC1 3.4471 7.4318 1.3936 14.8913
AMO1 GDSC1 3.5147 9.085 0.6227 19.7463
MOLT-13 GDSC1 3.5404 9.0623 0.6551 19.4565
Karpas-620 GDSC1 3.5784 7.4785 1.4771 13.8186
EB2 GDSC1 3.6398 6.2437 2.1414 8.5877
BALL-1 GDSC1 3.661 12.2153 -0.822 26.4157
RL GDSC1 3.6962 8.9842 0.8202 17.8762
SU-DHL-6 GDSC1 3.8607 7.5009 1.6878 11.3179
Karpas-422 GDSC1 3.8817 6.5468 2.1748 7.564
THP-1 GDSC1 3.9332 10.6184 0.194 20.7216
BC-1 GDSC1 3.947 19.2912 -4.1245 34.5121
Granta-519 GDSC1 3.9547 7.4591 1.7797 10.336
ML-2 GDSC1 4.0232 11.7631 -0.3052 22.9406
TK [Human B-cell lymphoma] GDSC1 4.1578 7.9528 1.6869 10.3989
KY821 GDSC1 4.1609 8.0633 1.635 10.7677
TUR GDSC1 4.1896 8.9814 1.2043 13.7108
ME1 GDSC1 4.1981 8.0856 1.6511 10.5389
L-363 GDSC1 4.2341 9.2167 1.1215 14.1288
EJM GDSC1 4.2642 7.172 2.1416 6.7266
HL-60 GDSC1 4.3121 11.376 0.1124 19.9173
Hs 445 GDSC1 4.368 8.4238 1.6081 10.3504
JJN-3 GDSC1 4.3928 6.0606 2.7389 2.1565
Karpas-299 GDSC1 4.407 8.0958 1.7947 8.8941
OCI-AML-3 GDSC1 4.4083 10.9688 0.3872 18.1121
DG-75 GDSC1 4.5062 6.9636 2.3969 4.2701
Jiyoye GDSC1 4.5086 9.8391 1.0177 13.9751
P31/FUJ GDSC1 4.5983 8.3987 1.7799 8.4846
RC-K8 GDSC1 4.6164 7.0605 2.419 3.8793
JVM-3 GDSC1 4.671 12.1445 0.0038 19.3776
DEL GDSC1 4.693 11.8575 0.1616 18.485
BC-3 GDSC1 4.7002 8.2807 1.9037 7.3383
MC116 GDSC1 4.7076 5.7555 3.0118 0.3405
KMS-11 GDSC1 4.9601 12.275 0.1525 17.7542
WSU-DLCL2 GDSC1 4.9721 6.2432 2.9377 0.4297
LP-1 GDSC1 5.0264 6.6904 2.7906 0.9896
EM-2 GDSC1 5.1353 10.7638 1.0096 12.2725
SU-DHL-10 GDSC1 5.1435 14.3355 -0.7245 21.4487
HT GDSC1 5.275 16.5652 -1.7253 24.9383
L-1236 GDSC1 5.2793 7.611 2.5373 2.005
K-562 GDSC1 5.326 11.3906 0.8383 12.8358
MOLT-16 GDSC1 5.6526 14.3688 -0.3736 18.499
L-428 GDSC1 5.7704 7.4544 2.8087 0.402
H9 GDSC1 5.7907 7.4363 2.8226 0.3559
KM-H2 GDSC1 5.9092 7.417 2.8722 0.2053
Mono-Mac-6 GDSC1 5.9123 9.0213 2.2637 2.6792
L-540 GDSC1 5.9507 7.6114 2.8202 0.3003
NOMO-1 GDSC1 6.0822 15.7765 -0.755 19.1319
PL-21 GDSC1 6.1532 8.8124 2.4587 1.4281
HDLM-2 GDSC1 6.2055 7.8642 2.8243 0.2141
ROS-50 GDSC1 7.1964 23.7436 -3.8413 26.5198
⏷ Show the Full List of 144 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 0.1539 5.42 -0.8586 43.2235
OACM5.1 C GDSC1 0.6073 5.1254 -0.2609 38.4301
ESO-51 GDSC1 2.291 8.763 -0.2792 29.4365
KYSE-50 GDSC1 4.305 8.4872 1.532 11.0776
OACP4 C GDSC1 4.4665 9.7298 1.0406 13.9522
FLO-1 GDSC1 4.7519 8.8911 1.6477 9.0186
KYSE-220 GDSC1 4.7532 8.1643 1.9927 6.5755
KYAE-1 GDSC1 4.9836 10.1692 1.192 11.5016
TE-12 GDSC1 5.2643 12.7033 0.1615 16.8581
HCE-4 GDSC1 5.8854 7.6783 2.7723 0.4496
SK-GT-4 GDSC1 6.0471 12.5061 0.7822 11.4178
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 3.0962 12.6872 -1.5277 30.912
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 GDSC1 -3.5801 -0.678 -3.5939 80.6901
SJNB-17 GDSC1 -3.3682 -1.1556 -3.3708 80.9459
IMR-5 GDSC1 -3.2338 -0.297 -3.253 77.5029
CHP-134 GDSC1 -2.6745 2.6535 -3.0476 66.6696
NH-12 GDSC1 -2.1665 2.0316 -2.3678 64.5507
GOTO GDSC1 -1.6391 2.757 -1.9441 59.3904
Kelly GDSC1 -1.2463 2.9933 -1.5724 55.8291
CHP-126 GDSC1 -1.1862 0.8387 -1.1994 56.5946
SiMa GDSC1 -0.862 2.3377 -1.0146 52.3976
KP-N-YS GDSC1 -0.0988 7.0289 -1.7999 46.2675
NB(TU)1 GDSC1 0.0387 5.7952 -1.1326 44.5314
NB1 GDSC1 0.3322 5.0344 -0.5166 41.1318
SJNB-13 GDSC1 0.5211 4.7266 -0.1963 38.7808
TGW GDSC1 0.7583 5.6802 -0.3323 37.706
GI-ME-N GDSC1 1.1863 7.9309 -0.9204 37.1543
SK-N-MC-IXC GDSC1 1.3699 4.4461 0.8172 28.384
NB69 GDSC1 1.7713 7.7224 -0.2563 31.7715
SK-N-SH GDSC1 1.9557 11.5472 -1.9579 36.4007
SJNB-12 GDSC1 1.9828 7.0106 0.2879 28.1403
SJNB-5 GDSC1 2.2278 11.471 -1.6761 34.5935
SK-N-DZ GDSC1 3.3303 5.9694 2.0279 10.5498
SJNB-7 GDSC1 3.6143 9.1812 0.6559 19.1856
CHP-212 GDSC1 3.8474 12.1654 -0.646 25.0557
SJNB-10 GDSC1 4.1866 8.819 1.2821 13.1882
SJNB-6 GDSC1 4.3437 11.4737 0.0881 19.9454
SK-N-AS GDSC1 5.0929 8.7646 1.9258 6.2641
KP-N-YN GDSC1 5.1362 10.8834 0.9528 12.6265
SK-N-BE(2)-M17 GDSC1 5.2365 6.8263 2.8282 0.6488
SK-N-FI GDSC1 5.4625 6.763 2.9375 0.2078
LA-N-6 GDSC1 5.7122 7.3208 2.8341 0.3593
SJNB-14 GDSC1 5.7479 7.3008 2.8544 0.2946
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 1.8601 7.7432 -0.1818 31.0123
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1599 GDSC1 -0.2905 2.4598 -0.4195 45.9341
CAL-148 GDSC1 0.1829 5.4684 -0.8476 42.997
CAL-85-1 GDSC1 0.276 3.9343 -0.1793 40.4849
MRK-nu-1 GDSC1 1.3665 9.3148 -1.4091 37.6065
DU4475 GDSC1 2.8047 15.6622 -3.2622 36.1704
HCC1806 GDSC1 3.4861 8.0197 1.1318 16.581
HDQ-P1 GDSC1 3.6157 9.8868 0.3045 21.2213
HCC38 GDSC1 3.6734 10.8124 -0.111 23.1921
MDA-MB-453 GDSC1 3.6912 7.983 1.3157 14.5793
OCUB-M GDSC1 4.0258 11.1908 -0.0181 21.5237
HCC2218 GDSC1 4.1874 9.1396 1.1245 14.255
CAL-120 GDSC1 4.2044 8.6152 1.3957 12.3437
Evsa-T GDSC1 4.3493 6.2854 2.6131 3.0908
JIMT-1 GDSC1 4.3874 6.6116 2.4865 3.8984
COLO 824 GDSC1 4.6114 9.8934 1.0654 13.3635
BT-474 GDSC1 4.6467 10.1596 0.9608 13.9351
CAMA-1 GDSC1 4.6514 7.6251 2.1803 5.4807
HCC70 GDSC1 4.6784 12.2929 -0.0638 19.7006
HCC1569 GDSC1 4.789 10.7313 0.7838 14.6316
UACC-812 GDSC1 4.824 6.7218 2.6819 1.8122
EFM-192A GDSC1 4.9002 11.2924 0.5896 15.4796
HCC1187 GDSC1 4.9019 7.2046 2.5162 2.6974
HCC1500 GDSC1 4.9048 7.1362 2.5474 2.4983
BT-20 GDSC1 4.9216 6.6712 2.7503 1.3042
EFM-19 GDSC1 5.0342 7.1649 2.6016 1.977
MDA-MB-436 GDSC1 5.0465 12.6436 0.0348 18.1264
HCC1419 GDSC1 5.0926 6.9973 2.6987 1.3711
CAL-51 GDSC1 5.0952 7.0586 2.6751 1.491
ZR-75-30 GDSC1 5.1407 13.1665 -0.1529 18.8118
BT-549 GDSC1 5.1842 10.1572 1.3318 10.066
HCC202 GDSC1 5.1945 8.0162 2.321 3.4323
HCC1395 GDSC1 5.2897 8.0263 2.3675 2.9843
MFM-223 GDSC1 5.2945 6.7417 2.8825 0.423
UACC-893 GDSC1 5.415 7.689 2.5703 1.6579
HCC1428 GDSC1 5.4155 7.0036 2.8345 0.5084
MDA-MB-157 GDSC1 5.4491 7.3836 2.7059 0.9766
MDA-MB-415 GDSC1 5.4766 7.01 2.8559 0.4082
T-47D GDSC1 5.5682 11.3019 1.0409 10.9854
MDA-MB-468 GDSC1 5.58 15.2874 -0.873 20.9054
HCC1937 GDSC1 5.6443 9.243 2.03 4.486
MDA-MB-361 GDSC1 5.6807 7.6405 2.7056 0.794
HCC2157 GDSC1 5.7163 7.2517 2.8599 0.2932
MDA-MB-175-VII GDSC1 5.7304 7.1782 2.8905 0.2213
YMB-1-E GDSC1 5.7766 8.5878 2.3763 2.2417
MDA-MB-231 GDSC1 5.8409 9.5019 2.0235 4.1897
HCC1954 GDSC1 5.9366 7.8986 2.7127 0.6037
Hs 578T GDSC1 5.9974 7.6735 2.8155 0.2944
MCF-7 GDSC1 6.1273 7.7311 2.842 0.2026
AU565 GDSC1 6.2427 8.4825 2.6199 0.7292
MDA-MB-330 GDSC1 6.4161 8.4847 2.6855 0.4475
BT-483 GDSC1 7.3661 20.2494 -2.0274 21.0546
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AM-38 GDSC1 -2.5582 2.9338 -2.9881 65.4664
GB-1 GDSC1 -1.6096 0.9332 -1.6408 61.2533
MOG-G-UVW GDSC1 0.6231 5.5825 -0.432 38.9101
SF268 GDSC1 1.102 10.4509 -2.209 40.5434
ONS-76 GDSC1 1.1256 5.2465 0.2337 33.0553
KNS-81-FD GDSC1 1.6718 5.3349 0.7598 27.0581
SNB-75 GDSC1 1.8745 7.0115 0.1834 29.2154
YKG-1 GDSC1 2.0073 8.9302 -0.6217 32.122
GaMG GDSC1 2.174 6.5362 0.6985 24.8866
Daoy GDSC1 2.2416 9.1231 -0.5018 30.5988
D-566MG GDSC1 2.2587 7.131 0.491 25.7058
MOG-G-CCM GDSC1 2.6464 6.6095 1.1058 20.1044
KINGS-1 GDSC1 2.6589 8.7164 0.0749 26.1638
GI-1 GDSC1 2.6908 8.4915 0.2149 25.3041
U-251MG GDSC1 2.9529 10.0492 -0.3321 26.9124
D-336MG GDSC1 3.1356 11.0203 -0.6612 27.6318
KS-1 [Human Krukenberg tumour] GDSC1 3.2966 8.1438 0.9126 18.7443
LNZTA3WT4 GDSC1 3.4257 4.4588 2.8617 3.6551
NMC-G1 GDSC1 3.512 7.2794 1.5229 13.7204
KNS-42 GDSC1 3.5794 11.3527 -0.4576 25.151
SF295 GDSC1 3.5886 8.4379 1.0063 17.0534
8-MG-BA GDSC1 3.732 8.3015 1.1893 15.3165
Onda 11 GDSC1 3.973 8.6055 1.2261 14.2546
M059J GDSC1 4.0607 11.0559 0.0765 20.9199
D-392MG GDSC1 4.1888 7.5762 1.8934 8.7852
D-423MG GDSC1 4.3731 10.8648 0.4119 18.0818
D283 Med GDSC1 4.5292 6.7335 2.5159 3.3906
Onda 10 GDSC1 4.583 8.8588 1.548 10.1705
Hs 683 GDSC1 4.5844 8.4983 1.7227 8.9298
LN-18 GDSC1 4.7142 5.706 3.0322 0.272
D-263MG GDSC1 4.7414 6.402 2.7741 1.4018
A-172 GDSC1 4.7809 10.9122 0.6896 15.2268
KALS-1 GDSC1 4.8091 12.7955 -0.2141 20.0603
U-87MG ATCC GDSC1 4.86 8.4718 1.9167 6.8585
SF126 GDSC1 4.8727 12.2964 0.0783 18.3968
DK-MG GDSC1 4.8933 7.6107 2.3322 3.9121
SK-MG-1 GDSC1 4.9756 7.7887 2.2997 3.9702
LN-229 GDSC1 5.268 6.9767 2.7846 0.7979
D-502MG GDSC1 5.3179 14.3018 -0.5804 20.3365
D-542MG GDSC1 5.4147 6.8095 2.9039 0.3039
YH-13 GDSC1 5.448 6.9498 2.8665 0.3913
42-MG-BA GDSC1 5.4875 10.3287 1.4455 8.5967
SF539 GDSC1 5.514 6.8411 2.9291 0.2091
LN-405 GDSC1 5.556 6.832 2.9471 0.1625
PFSK-1 GDSC1 5.6567 7.4385 2.7706 0.5772
CAS-1 GDSC1 5.7106 7.1055 2.9084 0.1921
U-118MG GDSC1 5.7757 7.3116 2.8607 0.2701
H4 GDSC1 5.8056 8.5578 2.4023 2.0681
D-247MG GDSC1 5.9916 8.2774 2.5946 0.9931
DBTRG-05MG GDSC1 6.0341 12.5033 0.7753 11.4876
Becker GDSC1 6.1476 7.4835 2.9316 0.0767
SW1088 GDSC1 6.2863 8.0113 2.8026 0.2322
SW1783 GDSC1 6.4244 8.3171 2.7469 0.3014
T98G GDSC1 6.8319 8.5657 2.8044 0.1198
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 -0.1877 4.7723 -0.9732 45.9622
TGBC1TKB GDSC1 5.6683 6.9384 2.9502 0.1312
TGBC24TKB GDSC1 6.111 7.8286 2.8028 0.2839
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1 1.3619 10.8933 -2.1807 39.3499
RL95-2 GDSC1 4.0041 12.2727 -0.5744 24.2274
MFE-296 GDSC1 5.0042 10.5408 1.0273 12.5097
KLE GDSC1 5.161 12.5518 0.1619 17.1398
MFE-319 GDSC1 5.7475 7.1968 2.8902 0.2168
EN GDSC1 5.7547 12.7507 0.4761 13.8646
MFE-280 GDSC1 6.0443 13.1877 0.4596 13.2561
AN3-CA GDSC1 6.1006 7.5866 2.8815 0.1449
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O GDSC1 1.6949 8.2805 -0.598 33.5045
KTCTL-21 GDSC1 2.4398 9.9375 -0.7263 30.6357
KTCTL-140 GDSC1 3.3283 11.8896 -0.9339 28.0144
769-P GDSC1 4.1549 15.6975 -2.1621 29.4382
RXF 393L GDSC1 4.2416 12.0666 -0.285 22.1367
LB1047-RCC GDSC1 4.4296 9.2101 1.2684 12.544
KTCTL-1M GDSC1 4.6015 9.07 1.4587 10.7427
BB65-RCC GDSC1 4.7256 7.3049 2.3726 3.9731
A-498 GDSC1 4.9025 6.5295 2.7984 1.081
OS-RC-2 GDSC1 4.999 7.4137 2.4776 2.7777
KTCTL-195 GDSC1 5.2045 7.3685 2.6008 1.7531
VMRC-RCW GDSC1 5.2724 7.4993 2.5799 1.7805
UO-31 GDSC1 5.4456 7.6748 2.5902 1.5214
SW13 GDSC1 5.4736 7.0854 2.8275 0.4977
LB996-RCC GDSC1 5.5957 7.717 2.6406 1.1314
KTCTL-26A GDSC1 5.7065 7.6407 2.716 0.7366
SN12C GDSC1 5.7269 7.3238 2.8386 0.3416
BFTC-909 GDSC1 5.7552 7.2601 2.8712 0.254
CAL-54 GDSC1 5.7972 7.705 2.7286 0.6337
HA7-RCC GDSC1 5.8604 7.7786 2.7266 0.6026
KMRC-1 GDSC1 5.8679 7.2276 2.9219 0.1325
TK-10 GDSC1 5.9462 8.2828 2.5735 1.1148
RCC10RGB GDSC1 6.1021 14.474 -0.1143 16.1213
KMRC-20 GDSC1 6.162 7.4576 2.9449 0.063
SW156 GDSC1 6.1888 8.0146 2.7665 0.338
ACHN GDSC1 6.211 14.0638 0.1538 14.5021
KTCTL-13 GDSC1 6.3261 8.0208 2.8134 0.2029
VMRC-RCZ GDSC1 6.4181 12.185 1.157 8.4135
Caki-1 GDSC1 6.4414 14.8689 -0.0767 15.134
LB2241-RCC GDSC1 6.5883 8.2585 2.8239 0.1343
NCC021 GDSC1 6.8877 8.5726 2.8208 0.0953
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RKO GDSC1 -0.4891 2.5853 -0.6577 48.2757
SW48 GDSC1 1.1539 10.3635 -2.1176 40.1443
SW837 GDSC1 1.3616 5.5273 0.3573 31.0533
HCT 15 GDSC1 1.4808 6.0665 0.2375 31.0019
SW620 GDSC1 1.5588 5.5463 0.5507 28.8999
CCK-81 GDSC1 1.6445 5.6486 0.5918 28.2007
HCT 116 GDSC1 1.82 4.898 1.1033 24.0755
SNU-81 GDSC1 2.292 6.6535 0.7541 23.9881
KM12 GDSC1 3.0612 7.0905 1.2379 17.4652
SNU-407 GDSC1 3.1183 10.2921 -0.312 26.1809
NCI-H716 GDSC1 3.475 7.0554 1.6046 13.2506
LS411N GDSC1 3.7189 17.2457 -3.2887 33.5008
SW626 GDSC1 4.0282 6.1041 2.4939 4.7159
SNU-1040 GDSC1 4.1108 11.5251 -0.1177 21.7451
LS1034 GDSC1 4.1964 16.4357 -2.4973 30.2521
CW-2 GDSC1 4.2202 10.459 0.4966 18.0792
T84 GDSC1 4.2956 12.3697 -0.3936 22.4755
COLO 320HSR GDSC1 4.5557 8.1314 1.879 7.8833
COLO205 GDSC1 4.6857 8.4732 1.8028 8.0938
SW948 GDSC1 4.7008 7.6555 2.197 5.2497
HCC2998 GDSC1 4.7337 9.0717 1.5489 9.7563
CaR-1 GDSC1 4.9537 8.7988 1.8232 7.2904
SNU-175 GDSC1 4.9564 9.4111 1.536 9.2673
GP5d GDSC1 4.9895 11.1417 0.7263 14.4156
C2BBe1 GDSC1 5.0387 12.4753 0.1114 17.7483
LS513 GDSC1 5.0493 11.3065 0.6883 14.4779
SW1417 GDSC1 5.1479 6.6238 2.8676 0.5636
SNU-61 GDSC1 5.1628 11.5665 0.6417 14.4445
SW1116 GDSC1 5.1671 6.6955 2.8487 0.6209
SNU-C5 GDSC1 5.1773 8.3721 2.1541 4.5476
SW1463 GDSC1 5.2991 7.149 2.7317 0.9981
HT-29 GDSC1 5.4441 10.5294 1.3244 9.4841
SNU-C1 GDSC1 5.4606 7.6847 2.5931 1.4902
HT115 GDSC1 5.4687 6.8975 2.8929 0.3095
HT-55 GDSC1 5.4694 6.6336 2.984 0.1216
RCM-1 [Human ESC] GDSC1 5.5047 6.9171 2.8993 0.2791
NCI-H747 GDSC1 5.5889 12.3591 0.552 13.8504
SNU-C2B GDSC1 5.5926 11.8117 0.8155 12.2999
LS180 GDSC1 5.6223 18.1299 -2.2377 25.7079
LS123 GDSC1 5.655 12.6658 0.4497 14.2612
COLO 678 GDSC1 5.8249 7.8128 2.6999 0.7154
CL-11 GDSC1 5.9689 7.7732 2.7701 0.4175
LoVo GDSC1 6.3026 8.2044 2.7419 0.3537
MDST8 GDSC1 8.454 19.0009 -0.7364 14.0217
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 2.7171 12.4059 -1.7117 32.8313
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 GDSC1 1.1039 7.4736 -0.7867 37.1875
JHH-1 GDSC1 1.3773 10.6474 -2.0463 39.0157
JHH-2 GDSC1 2.0453 12.6577 -2.4276 37.1064
JHH-7 GDSC1 2.9156 3.48 2.8366 6.0384
JHH-6 GDSC1 4.072 4.896 3.0694 0.648
JHH-4 GDSC1 5.0351 7.2254 2.5768 2.1202
HLE GDSC1 5.1618 15.7729 -1.4191 24.1601
HuH-1 GDSC1 5.1741 6.3102 2.9901 0.1893
Hep 3B2.1-7 GDSC1 5.2868 6.8388 2.8439 0.5561
SK-HEP-1 GDSC1 5.5553 9.9826 1.6468 7.1326
SNU-475 GDSC1 5.6639 11.9531 0.7953 12.245
Hep-G2/C3A GDSC1 5.8574 7.2916 2.8967 0.1749
SNU-423 GDSC1 6.0615 7.5559 2.8784 0.1578
SNU-387 GDSC1 6.2722 8.0183 2.7952 0.25
Huh-7 GDSC1 6.4269 7.9262 2.8794 0.0942
SNU-449 GDSC1 6.4277 8.2689 2.7647 0.2647
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC44 GDSC1 -0.7247 3.4919 -1.1352 50.7873
NCI-H520 GDSC1 -0.5386 2.6092 -0.7161 48.8362
COR-L95 GDSC1 -0.4003 70.9183 -33.6042 49.8127
SBC-3 GDSC1 -0.3554 4.156 -0.938 47.296
NCI-H358 GDSC1 -0.1122 5.972 -1.364 45.8989
NCI-H847 GDSC1 -0.0919 2.5699 -0.2249 43.6053
NCI-H2135 GDSC1 0.3214 6.9198 -1.3212 43.0134
NCI-H292 GDSC1 0.5098 4.4137 -0.0918 38.4672
CAL-12T GDSC1 0.6139 7.5202 -1.2957 41.2388
Lu-134-A GDSC1 0.6869 13.4401 -4.0526 44.506
Ms-1 GDSC1 0.7164 3.9047 0.3088 35.2765
NCI-H211 GDSC1 0.9877 3.3183 0.7816 30.8904
LCLC-97TM1 GDSC1 1.0951 7.2135 -0.6745 36.8794
NCI-H2110 GDSC1 1.1445 3.4562 0.9144 29.1087
EPLC-272H GDSC1 1.1529 6.2302 -0.1675 34.6965
NCI-H510A GDSC1 1.1545 10.0229 -1.9522 39.8241
NCI-H446 GDSC1 1.2657 3.6401 0.9914 27.8968
NCI-H1648 GDSC1 1.891 7.6403 -0.1028 30.5071
Lu-139 GDSC1 1.9746 5.0453 1.1971 22.6434
SBC-1 GDSC1 2.0792 19.453 -5.7797 41.6471
NCI-H647 GDSC1 2.1108 6.2108 0.7932 24.6101
COR-L23 GDSC1 2.1481 6.8704 0.5129 26.1033
DMS 273 GDSC1 2.1643 7.1927 0.3723 26.8123
NCI-H1876 GDSC1 2.1648 8.1435 -0.0907 29.153
NCI-H187 GDSC1 2.2435 13.1655 -2.504 36.5369
HOP-62 GDSC1 2.2935 9.6187 -0.6995 31.1524
NCI-H1963 GDSC1 2.3512 5.2334 1.489 18.7416
NCI-H810 GDSC1 2.3616 6.3778 0.9533 22.3992
IST-SL1 GDSC1 2.3903 8.2522 0.063 27.3889
SHP-77 GDSC1 2.3934 4.8051 1.7289 16.7847
NCI-H748 GDSC1 2.5033 6.9849 0.7898 22.8
NCI-H1975 GDSC1 2.6684 7.949 0.4641 24.0275
LC-2/ad GDSC1 2.7641 11.8588 -1.3981 31.705
UMC-11 GDSC1 2.7908 3.55 2.6772 7.8346
NCI-H3122 GDSC1 2.8557 10.2236 -0.5031 28.0438
LB647-SCLC GDSC1 2.8779 3.6101 2.7481 6.8678
NCI-H1436 GDSC1 2.9903 4.5033 2.4551 8.5523
HARA [Human squamous cell lung carcinoma] GDSC1 3.0717 9.7912 -0.1013 25.3658
SW1271 GDSC1 3.0982 7.7096 0.9609 19.1985
NCI-H2087 GDSC1 3.229 8.6835 0.5858 21.0388
NCI-H2731 GDSC1 3.2564 6.1195 1.8904 11.8881
NCI-H596 GDSC1 3.2627 4.423 2.743 5.1847
Lu-135 GDSC1 3.2691 15.183 -2.63 33.364
NCI-H1155 GDSC1 3.3076 7.9761 1.0056 18.092
SBC-5 GDSC1 3.4071 5.0945 2.529 6.3407
NCI-H1915 GDSC1 3.4426 8.5235 0.8442 18.6378
NCI-H2085 GDSC1 3.4491 9.3943 0.4142 21.2102
COR-L321 GDSC1 3.4647 6.9675 1.6401 13.0228
NCI-H2196 GDSC1 3.6326 9.238 0.6423 19.203
NCI-H1048 GDSC1 3.6652 9.7704 0.4028 20.493
NCI-H1694 GDSC1 3.6928 13.062 -1.2191 27.8263
Calu-6 GDSC1 3.6957 7.6392 1.4906 13.3143
NCI-H526 GDSC1 3.8333 10.468 0.1896 21.0863
NCI-H1755 GDSC1 3.9767 6.2097 2.4076 5.5075
NCI-H2171 GDSC1 4.0735 5.6452 2.7398 2.7943
COR-L105 GDSC1 4.1529 8.4689 1.4295 12.2644
A-427 GDSC1 4.2349 8.9908 1.2334 13.3714
SK-LU-1 GDSC1 4.2692 9.3733 1.0704 14.3585
NCI-H1836 GDSC1 4.337 13.1088 -0.7288 23.8329
NCI-H1688 GDSC1 4.3378 6.1044 2.6882 2.5979
LXF 289 GDSC1 4.3704 11.0849 0.301 18.713
NCI-H1734 GDSC1 4.451 9.8582 0.9663 14.4795
NCI-H226 GDSC1 4.4701 11.8156 0.0151 19.9311
PC-14 GDSC1 4.4711 8.0221 1.8742 8.1413
BEN GDSC1 4.4989 5.6362 2.9697 0.675
DMS 79 GDSC1 4.508 14.1804 -1.1286 24.9278
COR-L303 GDSC1 4.5483 10.7762 0.5867 16.528
Lu-65 GDSC1 4.5713 10.2964 0.8393 14.924
NCI-H2009 GDSC1 4.6083 6.433 2.6933 2.0761
LCLC-103H GDSC1 4.6541 7.3876 2.292 4.6844
NCI-H650 GDSC1 4.6704 11.0319 0.5508 16.3739
NCI-H2227 GDSC1 4.6757 13.2689 -0.5481 22.0159
NCI-H2029 GDSC1 4.7369 7.792 2.1561 5.4569
CPC-N GDSC1 4.7854 11.4406 0.4343 16.708
NCI-H2172 GDSC1 4.8144 7.2724 2.4383 3.3568
NCI-H2869 GDSC1 4.8423 7.7632 2.2334 4.6875
IA-LM GDSC1 4.8575 10.1774 1.1012 12.4342
SK-MES-1 GDSC1 4.8672 8.6566 1.8345 7.4179
NCI-H2803 GDSC1 4.8958 9.0533 1.6659 8.5246
NCI-H2347 GDSC1 4.9004 8.5669 1.8978 6.8958
NCI-H64 GDSC1 4.9065 6.2016 2.9267 0.5128
NCI-H2444 GDSC1 4.9128 6.0635 2.9799 0.3268
NCI-H322M GDSC1 4.9536 9.3972 1.5407 9.2418
NCI-H2081 GDSC1 4.9556 8.7669 1.8392 7.1744
HCC78 GDSC1 4.9581 8.8052 1.8229 7.2818
NCI-H1563 GDSC1 5.0075 7.3922 2.4914 2.6775
NCI-H838 GDSC1 5.0584 9.6179 1.5049 9.2231
NCI-H2795 GDSC1 5.1389 7.1305 2.6666 1.4835
Lu-165 GDSC1 5.1554 9.5616 1.5941 8.3836
RERF-LC-KJ GDSC1 5.1796 6.7997 2.8146 0.7461
IST-SL2 GDSC1 5.186 7.4433 2.561 1.9983
NCI-H720 GDSC1 5.1959 6.6675 2.8708 0.5203
NCI-H2170 GDSC1 5.2066 8.2067 2.2441 3.9034
NCI-H2373 GDSC1 5.2113 7.4958 2.5516 2.0165
EMC-BAC-1 GDSC1 5.2199 12.6431 0.1593 16.991
Lu-99A GDSC1 5.2234 12.3004 0.3284 16.0663
NCI-H2369 GDSC1 5.2282 6.683 2.8779 0.4757
EBC-1 GDSC1 5.2439 9.2009 1.817 6.672
NCI-H345 GDSC1 5.252 13.3411 -0.158 18.5291
NCI-H1437 GDSC1 5.26 7.9832 2.3704 3.0147
NCI-H1993 GDSC1 5.2698 6.929 2.8034 0.7204
NCI-H1435 GDSC1 5.2716 6.6824 2.895 0.3964
ABC-1 GDSC1 5.3041 10.7039 1.1513 10.9384
COLO 668 GDSC1 5.3179 7.8669 2.4497 2.4506
NCI-H2141 GDSC1 5.3202 12.8335 0.1378 16.832
NCI-H1781 GDSC1 5.3238 6.913 2.8314 0.5765
NCI-H727 GDSC1 5.3519 8.6754 2.118 4.453
RERF-LC-MS GDSC1 5.3622 10.1143 1.4667 8.7464
NCI-H513 GDSC1 5.3809 7.8764 2.4772 2.2048
NCI-H23 GDSC1 5.3994 8.699 2.134 4.2629
NCI-H1944 GDSC1 5.4584 16.9268 -1.7668 24.6008
RERF-LC-Sq1 GDSC1 5.4747 9.243 1.9346 5.413
NCI-H522 GDSC1 5.4774 7.4631 2.6875 1.0315
HCC33 GDSC1 5.5196 10.8553 1.2198 9.9773
NCI-H2722 GDSC1 5.5208 7.5206 2.684 1.0085
NCI-H1092 GDSC1 5.5979 12.7828 0.3549 14.9317
NCI-H1792 GDSC1 5.5991 7.2192 2.8276 0.4299
COR-L88 GDSC1 5.6068 7.4771 2.7364 0.7306
NCI-H1869 GDSC1 5.6174 10.441 1.4739 8.1222
NCI-H196 GDSC1 5.6219 7.3971 2.772 0.5936
NCI-H841 GDSC1 5.6269 11.8506 0.8196 12.1909
NCI-H1838 GDSC1 5.6439 7.3781 2.7876 0.5292
NCI-H3255 GDSC1 5.6487 7.995 2.5554 1.4741
NCI-H1770 GDSC1 5.6543 7.0402 2.9107 0.2036
NCI-H524 GDSC1 5.6731 7.5679 2.7295 0.7101
ChaGo-K-1 GDSC1 5.6984 7.8833 2.6208 1.1261
LOU-NH91 GDSC1 5.6993 7.4775 2.7731 0.5444
NCI-H460 GDSC1 5.7086 6.8538 2.992 0.071
NCI-H1304 GDSC1 5.7157 7.2604 2.8567 0.3011
NCI-H1651 GDSC1 5.7176 7.6707 2.7093 0.7537
NCI-H1650 GDSC1 5.7289 8.4042 2.4284 2.0237
NCI-H82 GDSC1 5.7497 13.9652 -0.1104 16.9769
HCC827 GDSC1 5.7555 7.4955 2.7883 0.4671
NCI-H441 GDSC1 5.7853 7.4388 2.8197 0.3657
NCI-H2228 GDSC1 5.7996 14.4051 -0.2883 17.7176
NCI-H69 GDSC1 5.8057 7.6641 2.7468 0.5684
NCI-H1573 GDSC1 5.8114 7.894 2.6643 0.8565
NCI-H1581 GDSC1 5.8284 7.2162 2.9121 0.156
NCI-H1666 GDSC1 5.9042 8.5542 2.4494 1.7183
NCI-H2122 GDSC1 5.9184 7.1661 2.9594 0.0775
LC-1/sq GDSC1 5.9283 9.9177 1.8898 4.8612
NCI-H2804 GDSC1 5.9347 8.6169 2.4383 1.7396
NCI-H1623 GDSC1 5.9373 7.7691 2.7596 0.461
EKVX GDSC1 5.944 7.9716 2.689 0.6778
NCI-H2591 GDSC1 5.9662 12.3363 0.8102 11.4394
NCI-H2595 GDSC1 5.9719 14.5289 -0.2292 17.0012
NCI-H661 GDSC1 5.9752 14.2615 -0.0985 16.3528
Calu-3 GDSC1 6.0167 7.6406 2.8338 0.2491
NCI-H209 GDSC1 6.0303 7.8398 2.7694 0.3927
NCI-H2405 GDSC1 6.033 9.0362 2.3156 2.2476
HOP-92 GDSC1 6.0554 7.9113 2.7535 0.4237
DMS 53 GDSC1 6.0621 7.5808 2.8702 0.1706
NCI-H2342 GDSC1 6.0636 8.1574 2.6682 0.6755
NCI-H1693 GDSC1 6.1088 7.7724 2.8214 0.2463
NCI-H1703 GDSC1 6.1269 7.9606 2.7627 0.3704
A-549 GDSC1 6.1283 7.7037 2.8517 0.1857
DMS 114 GDSC1 6.1705 7.8202 2.8269 0.2185
NCI-H1793 GDSC1 6.1783 7.7236 2.8623 0.1575
HCC15 GDSC1 6.1932 8.1417 2.7235 0.4432
NCI-H2818 GDSC1 6.2611 7.9123 2.8274 0.1948
NCI-H1299 GDSC1 6.266 7.9625 2.8121 0.2203
NCI-H1568 GDSC1 6.3207 8.2205 2.7429 0.3449
EMC-BAC-2 GDSC1 6.3534 15.7156 -0.5394 17.5274
PaCa-3 GDSC1 6.3581 15.7154 -0.5361 17.501
LK-2 GDSC1 6.4984 16.4574 -0.7969 18.3176
NCI-H1355 GDSC1 6.5484 8.6212 2.6864 0.3932
NCI-H2291 GDSC1 6.5484 8.1456 2.8478 0.1118
NCI-H2461 GDSC1 6.5677 8.3717 2.7788 0.2034
SW1573 GDSC1 7.0704 9.2584 2.654 0.295
NCI-H2023 GDSC1 7.2205 15.3864 0.1751 12.1931
NCI-H2030 GDSC1 7.5428 19.9319 -1.7558 19.754
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 2.9047 10.6791 -0.6881 28.6181
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-450 GDSC1 -0.1026 4.6004 -0.8188 45.0553
TE-15 GDSC1 1.5328 8.2947 -0.7591 34.8736
TE-6 GDSC1 1.9402 7.1708 0.1703 28.956
KYSE-180 GDSC1 2.0381 6.5523 0.5604 26.3626
TE-10 GDSC1 3.3305 8.3233 0.8512 19.0113
TE-9 GDSC1 3.8429 7.5158 1.6667 11.5317
KYSE-410 GDSC1 3.9993 9.5552 0.7749 17.125
KYSE-510 GDSC1 4.5145 8.3947 1.7247 9.1042
T.T GDSC1 4.5623 6.7429 2.531 3.2212
TE-8 GDSC1 4.5778 13.2783 -0.6272 22.6591
KYSE-150 GDSC1 4.9313 8.5302 1.9344 6.5685
TE-5 GDSC1 4.9408 9.3089 1.5741 9.0453
TE-11 GDSC1 4.9454 7.1764 2.5514 2.4083
KYSE-70 GDSC1 4.9761 7.7089 2.3355 3.7317
OE21 GDSC1 5.0539 7.6543 2.4026 3.1572
OE19 GDSC1 5.4913 6.7586 2.9493 0.1757
TE-4 GDSC1 5.7197 7.4104 2.8052 0.4358
COLO 680N GDSC1 5.9139 7.6143 2.8057 0.3486
KYSE-270 GDSC1 6.0472 8.2763 2.6178 0.8632
KYSE-140 GDSC1 6.0726 8.165 2.669 0.6674
TE-1 GDSC1 6.1807 13.2671 0.5104 12.6567
KYSE-520 GDSC1 6.299 8.2897 2.7107 0.4314
EC-GI-10 GDSC1 6.3598 7.949 2.8491 0.141
OE33 GDSC1 6.4302 14.5274 0.0777 14.3853
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC1 -0.277 5.5896 -1.3826 47.0928
OVCAR-8 GDSC1 -0.1432 3.9818 -0.6503 45.0811
ES-2 GDSC1 0.4549 3.9248 0.0182 38.4157
OVK18 GDSC1 1.1462 4.3567 0.6127 30.9174
TOV-112D GDSC1 1.1531 6.1621 -0.1368 34.5683
IGROV-1 GDSC1 2.6406 9.1392 -0.1514 27.3455
OVCAR-4 GDSC1 3.0493 7.2162 1.1648 18.0197
DOV13 GDSC1 3.3331 6.7168 1.6565 13.3801
OV56 GDSC1 3.4173 10.8126 -0.3213 25.1111
EFO-21 GDSC1 3.9792 11.5342 -0.226 22.7087
RMG-I GDSC1 4.3782 8.0274 1.8077 8.8789
OAW42 GDSC1 4.4965 6.7233 2.5013 3.5591
OVKATE GDSC1 4.5478 8.1101 1.884 7.8681
JHOS-2 GDSC1 4.6145 9.4598 1.2788 11.9375
TYK-nu GDSC1 4.8216 8.9017 1.689 8.5507
OC 314 GDSC1 4.8492 7.6413 2.2928 4.2663
EFO-27 GDSC1 4.9287 9.3935 1.526 9.4062
OVISE GDSC1 4.9713 13.7132 -0.5457 21.1451
Caov-3 GDSC1 5.0556 10.5486 1.0588 12.1711
TOV-21G GDSC1 5.1013 6.573 2.8676 0.5966
SK-OV-3 GDSC1 5.3845 12.0918 0.5413 14.4377
FU-OV-1 GDSC1 5.4477 7.1401 2.7972 0.617
OVCAR-5 GDSC1 5.4657 9.2029 1.9474 5.3465
OVCAR-3 GDSC1 5.4823 7.2393 2.7744 0.6765
OAW28 GDSC1 5.7289 7.8569 2.6439 1.0019
OVTOKO GDSC1 5.7988 12.4657 0.6408 12.8211
Kuramochi GDSC1 5.8047 8.8539 2.2802 2.7335
OV-90 GDSC1 7.0721 15.7215 -0.0722 13.7245
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PSN1 GDSC1 -0.5047 2.3184 -0.6261 48.4095
SUIT-2 GDSC1 0.5702 8.0752 -1.5946 42.0676
MZ-PC-1 GDSC1 1.2207 8.3643 -1.0924 37.4742
HuP-T4 GDSC1 1.31 5.881 0.1482 32.3935
HPAC GDSC1 2.3792 9.368 -0.4983 29.9858
PaTu 8902 GDSC1 2.6112 8.2269 0.2751 25.322
Panc 10.05 GDSC1 2.7126 9.4633 -0.249 27.4994
Capan-1 GDSC1 3.3743 11.8066 -0.854 27.5403
PaTu 8988t GDSC1 3.4454 7.9897 1.1133 16.8552
KP-2 GDSC1 4.0648 5.47 2.8151 2.2811
HuP-T3 GDSC1 4.3686 9.6266 1.0195 14.3863
Panc 03.27 GDSC1 4.4237 10.6316 0.5652 17.0362
SU.86.86 GDSC1 4.4347 7.7131 1.9978 7.3368
PL4 GDSC1 4.4693 7.1606 2.2823 5.1754
KP-4 GDSC1 4.7314 11.6862 0.2742 17.7611
Panc 08.13 GDSC1 4.8105 8.8161 1.7223 8.3451
QGP-1 GDSC1 4.904 13.3303 -0.4071 20.7037
YAPC GDSC1 4.9447 10.9993 0.7639 14.3128
BxPC-3 GDSC1 4.9814 8.5417 1.9601 6.2757
SW1990 GDSC1 5.0106 7.3452 2.5132 2.5386
DAN-G GDSC1 5.1162 7.2307 2.6148 1.7908
KP-3 GDSC1 5.2763 11.7094 0.6512 14.0847
CFPAC-1 GDSC1 5.4926 8.3076 2.3526 2.7625
Hs 766T GDSC1 5.6209 7.099 2.8783 0.2853
Capan-2 GDSC1 5.6484 9.2046 2.049 4.3595
AsPC-1 GDSC1 5.6752 10.0031 1.7086 6.4826
Panc 02.03 GDSC1 5.7606 11.7596 0.9494 11.0882
HPAF-II GDSC1 5.805 13.2715 0.2609 14.9188
Panc 04.03 GDSC1 5.9124 7.57 2.8206 0.3131
MIA PaCa-2 GDSC1 6.0179 7.4536 2.8977 0.1378
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2052 GDSC1 5.4769 8.8139 2.1263 4.1735
MPP 89 GDSC1 5.6751 7.3243 2.819 0.4177
NCI-H2452 GDSC1 5.7261 7.6132 2.7341 0.6591
NCI-H28 GDSC1 5.9165 14.4759 -0.2417 17.1993
MSTO-211H GDSC1 6.1844 8.1657 2.7117 0.4792
IST-Mes1 GDSC1 8.1609 20.9119 -1.8131 18.7215
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1 3.1231 8.5531 0.561 21.5979
DU145 GDSC1 3.708 8.3548 1.1436 15.7118
PC-3 GDSC1 4.2122 7.55 1.9227 8.5
22Rv1 GDSC1 5.0925 14.6222 -0.9034 22.3459
VCaP GDSC1 6.3571 18.4898 -1.879 22.7799
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 5.1544 7.6306 2.4661 2.5988
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-431 GDSC1 -1.0721 3.036 -1.393 54.2182
IST-MEL1 GDSC1 1.0005 2.9473 0.8843 30.1766
Mel Ho GDSC1 1.1538 2.3623 1.1341 27.653
IGR-1 GDSC1 1.2265 2.4893 1.1989 26.7945
WM35 GDSC1 1.2612 3.1719 1.1175 27.1097
CHL-1 GDSC1 1.3127 4.0661 0.8986 28.2101
RPMI-7951 GDSC1 1.4682 5.7991 0.3457 30.5161
IPC-298 GDSC1 2.3245 4.5623 1.7684 16.8262
A-375 GDSC1 2.5289 9.0807 -0.2217 28.1435
SK-MEL-24 GDSC1 2.6252 3.279 2.5781 9.4423
Mel JuSo GDSC1 2.7542 8.2235 0.4043 24.0027
IGR-37 GDSC1 2.7978 3.2242 2.7771 7.1124
WM1552C GDSC1 3.1236 8.7053 0.4854 22.0388
SK-MEL-5 GDSC1 3.3783 5.291 2.4071 7.4038
MZ-MEL-2 GDSC1 3.6211 6.1377 2.1795 8.3526
SK-MEL-30 GDSC1 3.6757 6.5198 2.0321 9.3143
A-388 GDSC1 4.0222 10.342 0.4016 19.2738
COLO 679 GDSC1 4.073 11.4008 -0.0855 21.7085
WM115 GDSC1 4.2659 11.0861 0.2207 19.4842
SK-MEL-28 GDSC1 4.2872 5.3291 2.9953 0.7785
SK-MEL-2 GDSC1 4.3523 6.1594 2.6719 2.6802
COLO 800 GDSC1 4.3922 12.7233 -0.4945 22.635
451Lu GDSC1 4.4114 7.1043 2.2716 5.392
GAK GDSC1 4.4717 7.5347 2.1074 6.44
UACC-62 GDSC1 4.7686 5.7968 3.0205 0.2792
LB373-MEL-D GDSC1 4.7741 6.3431 2.8137 1.1485
G-361 GDSC1 4.8021 10.6732 0.8214 14.3627
LOX-IMVI GDSC1 4.9196 9.2236 1.6007 8.9158
A2058 GDSC1 4.9281 6.1135 2.9678 0.3563
LB2518-MEL GDSC1 4.9425 6.1379 2.9645 0.3587
CP66-MEL GDSC1 4.9434 6.3141 2.8997 0.5895
SK-MEL-3 GDSC1 5.0195 6.3017 2.935 0.41
COLO 783 GDSC1 5.034 6.5695 2.8408 0.7577
A101D GDSC1 5.045 6.3245 2.9367 0.3898
MZ-MEL-7 GDSC1 5.0962 11.2081 0.7687 13.8668
M14 GDSC1 5.103 7.0694 2.6744 1.4852
WT2-iPS GDSC1 5.1629 6.1437 3.0429 0.0966
WM278 GDSC1 5.1993 7.775 2.4278 2.7605
RVH-421 GDSC1 5.2215 12.6651 0.1498 17.0371
UACC-257 GDSC1 5.249 10.075 1.4128 9.3718
Hs 938.T GDSC1 5.2748 6.5828 2.9318 0.2906
HMV-II GDSC1 5.3277 8.9042 2.0019 5.2601
MMAc-SF GDSC1 5.376 6.574 2.9715 0.1657
MeWo GDSC1 5.3816 6.8305 2.884 0.3734
G-mel GDSC1 5.418 7.2581 2.7407 0.8566
SK-MEL-1 GDSC1 5.4964 6.7617 2.95 0.1729
SH-4 GDSC1 5.5085 7.9129 2.5237 1.7896
CP50-MEL-B GDSC1 5.5844 7.1051 2.8627 0.3392
COLO 792 GDSC1 5.5875 7.0572 2.8807 0.2923
HT-144 GDSC1 5.6459 12.0654 0.7301 12.6746
VMRC-MELG GDSC1 5.6808 7.0827 2.9056 0.2059
Hs 940.T GDSC1 5.776 7.4363 2.8172 0.3765
COLO 829 GDSC1 5.7872 14.5326 -0.3586 18.0827
DJM-1 GDSC1 6.1821 7.7908 2.841 0.1908
WM793 GDSC1 6.6441 13.2411 0.8107 9.9658
EquiPSC Line K2 GDSC1 6.5964 8.6624 2.6895 0.3687
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -2.7722 0.7064 -2.8369 71.7204
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-LMS-1 GDSC1 -1.6753 1.9107 -1.8185 60.741
EW-8 GDSC1 0.027 8.7185 -2.4321 46.0951
A-204 GDSC1 0.5192 8.2677 -1.7343 42.5875
G-401 GDSC1 0.6488 11.1927 -2.9969 43.6627
Hs 633.T GDSC1 1.8474 8.1737 -0.4022 32.0071
SW982 GDSC1 2.9053 11.2445 -0.9697 29.7014
RD GDSC1 3.8681 14.176 -1.6333 28.6829
HT-1080 GDSC1 4.5513 7.9316 1.9714 7.2267
G-402 GDSC1 4.6245 13.9753 -0.937 23.8255
VA-ES-BJ GDSC1 4.8864 6.9812 2.6041 2.1806
KYM-1 GDSC1 4.9143 6.7094 2.7313 1.4139
MES-SA GDSC1 5.0272 6.2679 2.9503 0.3568
SK-UT-1 GDSC1 5.1389 7.9043 2.3397 3.4101
MFH-ino GDSC1 5.2786 11.9185 0.5519 14.6568
RKN GDSC1 5.3911 6.8262 2.8891 0.3542
Rh41 GDSC1 5.4468 6.9912 2.8512 0.4377
SW684 GDSC1 5.5158 6.6801 2.9844 0.1115
SW872 GDSC1 5.5392 7.0467 2.8665 0.3488
GCT GDSC1 5.71 7.1128 2.9057 0.1974
Rh30 GDSC1 6.3006 8.0188 2.8051 0.2238
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC1 -2.1377 2.3274 -2.3932 63.825
RF-48 GDSC1 0.0431 3.1854 -0.2144 42.4325
MKN28 GDSC1 0.371 7.3575 -1.4663 42.9704
SNU-1 GDSC1 1.2754 6.8731 -0.338 34.6878
23132/87 GDSC1 1.7804 10.1707 -1.4394 35.8028
NUGC-4 GDSC1 4.0266 10.5652 0.294 19.8625
RERF-GC-1B GDSC1 4.0838 10.7595 0.242 19.959
MKN45 GDSC1 4.1985 8.8378 1.2817 13.1536
GCIY GDSC1 4.8822 7.872 2.2076 4.7812
MKN1 GDSC1 4.947 9.3855 1.5419 9.2503
ECC10 GDSC1 5.0231 8.7374 1.8953 6.6298
SNU-5 GDSC1 5.2924 6.5352 2.9549 0.2269
Fu97 GDSC1 5.2934 7.2597 2.6859 1.2153
SCH GDSC1 5.4743 6.8314 2.9181 0.2462
IM95 GDSC1 5.5494 10.7752 1.2763 9.5466
NUGC-3 GDSC1 5.5866 7.4768 2.7283 0.7757
SNU-16 GDSC1 5.6291 6.9513 2.9322 0.1702
MKN7 GDSC1 5.6437 7.6896 2.6717 0.9568
AGS GDSC1 5.6849 10.5523 1.4639 8.0397
OCUM-1 GDSC1 5.7159 7.5941 2.737 0.6553
TGBC11TKB GDSC1 5.844 7.5087 2.8169 0.3485
TMK-1 GDSC1 5.9406 7.794 2.752 0.4812
NCI-N87 GDSC1 6.433 8.6566 2.6308 0.5907
Hs 746.T GDSC1 7.2246 15.9448 -0.0807 13.4483
HGC-27 GDSC1 8.2843 19.9848 -1.2977 16.5949
SNG-M GDSC1 5.8535 7.477 2.8315 0.3092
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT2609-C02 GDSC1 0.9967 10.2459 -2.2095 41.0205
IHH-4 GDSC1 2.9087 11.4186 -1.0537 29.9945
CAL-62 GDSC1 4.0415 7.4135 1.8665 9.4207
8505C GDSC1 4.7897 11.2086 0.5511 16.0224
HTC-C3 GDSC1 4.8513 9.154 1.5886 9.1733
K5 GDSC1 4.9477 6.4826 2.837 0.8517
WRO GDSC1 5.1685 6.8072 2.8071 0.7865
CGTH-W-1 GDSC1 5.2078 7.2623 2.6456 1.5109
8305C GDSC1 5.3246 6.8159 2.8673 0.4544
ASH-3 GDSC1 5.4901 6.5877 3.0064 0.0865
KMH-2 GDSC1 5.5484 7.4097 2.7377 0.7675
TT GDSC1 5.6107 7.1644 2.8516 0.3572
ML-1 [Human leukemia] GDSC1 5.6363 14.1187 -0.2637 18.0188
FTC-133 GDSC1 5.6691 7.0703 2.9057 0.2093
B-CPAP GDSC1 6.5916 15.3856 -0.2231 15.5035
BHT-101 GDSC1 6.6659 16.7586 -0.8279 18.064
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-06A GDSC1 0.051 3.669 -0.3409 42.7529
SCC-25 GDSC1 0.1973 3.7076 -0.1932 41.1324
BB30-HNC GDSC1 1.3661 8.7479 -1.1362 36.8715
HO-1-u-1 GDSC1 1.5499 7.1402 -0.1923 32.6237
SAS GDSC1 2.3592 8.6518 -0.1623 28.6072
JHU-011 GDSC1 2.4716 8.626 -0.0479 27.5745
BHY GDSC1 2.7887 7.5886 0.7502 21.8092
PCI-04B GDSC1 3.0215 8.9952 0.2531 23.7433
NCI-H3118 GDSC1 3.1413 11.4421 -0.8672 28.4333
SCC-9 GDSC1 3.2194 10.9475 -0.5541 26.8713
HO-1-N-1 GDSC1 3.934 7.7472 1.6216 11.5704
Ca9-22 GDSC1 4.2657 8.2002 1.6439 10.3906
LB771-HNC GDSC1 4.5302 7.5985 2.1155 6.2359
FaDu GDSC1 4.5459 6.534 2.615 2.6898
CAL-27 GDSC1 4.5913 10.495 0.7565 15.3766
SCC-15 GDSC1 4.666 10.7027 0.7091 15.4445
SKN-3 GDSC1 4.6811 7.9285 2.0573 6.2878
PCI-38 GDSC1 4.7043 10.8584 0.6606 15.6237
OSC-20 GDSC1 4.7816 10.5628 0.8606 14.178
CAL-33 GDSC1 5.0469 11.1821 0.747 14.1326
KOSC-2 GDSC1 5.079 8.8387 1.883 6.5882
HSC-3 GDSC1 5.1137 6.3597 2.9504 0.3125
PCI-15A GDSC1 5.1195 6.8564 2.7669 1.0084
BICR 78 GDSC1 5.1593 9.1083 1.8078 6.9222
JHU-022 GDSC1 5.1912 10.0047 1.4086 9.5411
DOK GDSC1 5.2024 7.7528 2.4389 2.6886
OSC-19 GDSC1 5.2914 7.2454 2.6907 1.1945
Detroit 562 GDSC1 5.4401 6.9848 2.8509 0.4421
HSC-2 GDSC1 5.4434 6.8672 2.8942 0.317
KON GDSC1 5.5947 7.1931 2.8353 0.4097
HSC-4 GDSC1 5.6157 7.0882 2.8802 0.2827
BB49-HNC GDSC1 5.6291 8.0479 2.5254 1.6421
PCI-30 GDSC1 5.6594 7.405 2.7839 0.5324
BICR 22 GDSC1 5.697 7.1212 2.8982 0.2159
SAT [Human HNSCC] GDSC1 5.6989 11.3557 1.0995 10.3121
BICR 31 GDSC1 5.8227 7.4479 2.8304 0.3237
SCC-4 GDSC1 5.9253 10.7632 1.5114 7.2346
BICR 10 GDSC1 6.003 7.5747 2.8515 0.2183
PE/CA-PJ15 GDSC1 6.2393 8.0115 2.7858 0.2787
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 GDSC1 0.9716 5.96 -0.2326 36.0228
BFTC-905 GDSC1 3.3853 5.3358 2.3905 7.509
639V GDSC1 4.4557 9.1898 1.2972 12.2716
647V GDSC1 4.7505 7.5789 2.2626 4.6808
KU-19-19 GDSC1 4.9239 6.1033 2.9698 0.3523
SW1710 GDSC1 4.973 8.2117 2.1069 5.281
CAL-29 GDSC1 5.2116 6.886 2.7953 0.8
TCCSUP GDSC1 5.2349 6.885 2.8054 0.7394
RT-4 GDSC1 5.2768 15.3733 -1.1366 22.7794
HT-1197 GDSC1 5.3572 7.1621 2.7516 0.8612
T24 GDSC1 5.7854 10.1619 1.7011 6.3111
HT-1376 GDSC1 5.8843 7.6399 2.7856 0.4134
J82 GDSC1 6.0323 8.1688 2.6516 0.7515
SW780 GDSC1 6.1682 7.5829 2.9058 0.1014
5637 GDSC1 6.5976 17.5016 -1.2314 19.8632
RT-112 GDSC1 7.028 13.7262 0.8172 9.1736
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1 -2.894 5.4424 -4.1301 63.2922
NEC8 GDSC1 -2.537 -0.4024 -2.5415 72.3784
PA-1 GDSC1 -1.715 2.6664 -2.0062 60.1116
SW954 GDSC1 0.8267 10.9677 -2.7194 42.5507
HEY GDSC1 1.5765 6.8203 -0.0159 31.7041
OVMIU GDSC1 1.8435 10.1897 -1.3907 35.3911
CAL-39 GDSC1 2.3558 5.4634 1.3854 19.4645
C-33 A GDSC1 2.5267 9.4569 -0.4104 28.9885
SW962 GDSC1 2.5961 7.3459 0.6971 22.9635
Ca Ski GDSC1 2.6745 12.8931 -1.9916 33.7599
BPH-1 GDSC1 2.751 14.8926 -2.9238 35.6733
ME-180 GDSC1 4.4314 10.1922 0.7876 15.6679
SiSo GDSC1 4.4815 8.6406 1.5829 10.2071
HeLa GDSC1 4.616 6.0654 2.8518 1.1388
OMC-1 [Human cervical carcinoma] GDSC1 4.6202 8.0497 1.9607 7.1297
ACC-OV7 GDSC1 4.7857 9.175 1.5346 9.7174
SKN GDSC1 4.8949 17.8338 -2.6437 28.7378
DoTc2 4510 GDSC1 5.0812 8.3087 2.1269 4.9198
OV17R GDSC1 5.1897 8.1379 2.2651 3.7985
PEO1 GDSC1 5.3358 7.445 2.6316 1.4359
JEG-3 GDSC1 5.4367 6.574 2.9927 0.1152
HT-3 GDSC1 5.5438 11.0838 1.1279 10.5011
OVCA420 GDSC1 5.6065 7.4593 2.7429 0.7067
SKG-IIIa GDSC1 5.6966 7.4295 2.7894 0.4944
JHOS-3 GDSC1 5.7027 8.0169 2.5709 1.3464
NCC-IT GDSC1 5.7226 7.1077 2.9119 0.1824
OVCA433 GDSC1 5.8087 10.3839 1.6146 6.8163
SiHa GDSC1 5.8141 6.8281 3.0351 0.028
HEC-1 GDSC1 5.8147 7.1463 2.9308 0.13
C-4-I GDSC1 5.8297 7.5036 2.8134 0.3633
NT2-D1 GDSC1 5.9644 11.5445 1.1775 9.233
JAR GDSC1 5.9694 7.4304 2.8888 0.1616
MS751 GDSC1 5.9933 7.7335 2.7931 0.3482
SW756 GDSC1 6.1357 7.6395 2.8759 0.1461
UWB1.289 GDSC1 6.1739 8.2238 2.687 0.5553
DSH1 GDSC1 6.2219 8.2012 2.7132 0.4582
LB831-BLC GDSC1 6.3294 8.1405 2.7737 0.2758
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.