Details of the Drug

General Information of Drug (ID: DMQP0X5)

Drug Name
Lebrikizumab
Synonyms RG3637
Indication
Disease Entry ICD 11 Status REF
Severe asthma CA23 Phase 3 [1]
Atopic dermatitis EA80 Phase 2 [2]
Chronic obstructive pulmonary disease CA22 Phase 2 [3]
Idiopathic pulmonary fibrosis CB03.4 Phase 2 [4]
Drug Type
Monoclonal antibody
Cross-matching ID
UNII
U9JLP7V031
DrugBank ID
DB11914
TTD ID
D0SM8S
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-13 (IL13) TT0GVCH IL13_HUMAN Modulator [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7684).
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 ClinicalTrials.gov (NCT00971035) A Study to Evaluate Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Not Taking Inhaled Corticosteroids
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 The potential of biologics for the treatment of asthma. Nat Rev Drug Discov. 2012 Dec;11(12):958-72.