Details of the Drug

General Information of Drug (ID: DMQRZ4T)

Drug Name
NSC632839
Synonyms
157654-67-6; NSC 632839 hydrochloride; NSC-632839; Nsc 632839; NSC-632839 hydrochloride; 3,5-BIS[(4-METHYLPHENYL)METHYLENE]-4-PIPERIDONE HYDROCHLORIDE; 157654-67-6 (HCl); MLS002701647; C21H21NO.ClH; (3E,5E)-3,5-bis[(4-methylphenyl)methylidene]piperidin-4-one;hydrochloride; CHEMBL1990474; DTXSID10417701; AMY19345; BCP28077; EX-A4187; 2599AH; s4922; AKOS024457219; CS-6014; BS-15510; HY-100708; NSC 632839, >=98% (HPLC); J-009433; 3,5-bis((E)-4-methylbenzylidene)piperidin-4-one hydrochloride; 4-Piperidione,3,5-bis[(4-methylphenyl)methylene] hydrochloride; 4-Piperidinone,5-bis[(4-methylphenyl)methylene]-, hydrochloride; 4-Piperidinone, 3,5-bis[(4-methylphenyl)methylene]-, hydrochloride (1:1)
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Preclinical [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 339.9
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 2
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Chemical Identifiers
Formula
C21H22ClNO
IUPAC Name
(3E,5E)-3,5-bis[(4-methylphenyl)methylidene]piperidin-4-one;hydrochloride
Canonical SMILES
CC1=CC=C(C=C1)/C=C\\2/C(=O)/C(=C/C3=CC=C(C=C3)C)/CNC2.Cl
InChI
InChI=1S/C21H21NO.ClH/c1-15-3-7-17(8-4-15)11-19-13-22-14-20(21(19)23)12-18-9-5-16(2)6-10-18;/h3-12,22H,13-14H2,1-2H3;1H/b19-11+,20-12+;
InChIKey
ZOKZLTXPTLIWOJ-BYCVLTJGSA-N
Cross-matching ID
PubChem CID
5351362
CAS Number
157654-67-6
TTD ID
DRT90B

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ubiquitin thioesterase L1 (UCHL1) TTX9IFP UCHL1_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 148 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.7305 1.2971 0.7305 28.7396
JK1 CTRP2 0.8158 6.2322 0.0582 40.7239
JM1 CTRP2 0.4933 1.2182 0.4933 30.3203
OCI-AML-3 CTRP2; CTRP1 -0.8667 0.0489 -0.8667 39.4388
SK-MM-2 CTRP2 -0.6193 2.7663 -0.6954 37.9653
Ri-1 CTRP2 -0.457 1.7825 -0.4662 49.9667
KMS-11 CTRP2; CTRP1 -0.3136 1.4934 -0.316 38.3156
NU-DUL-1 CTRP2; CTRP1 0.0368 1.7483 0.0343 45.561
PL21 CTRP2; CTRP1 0.128 1.7864 0.1258 35.1662
Peer CTRP2 0.2585 2.285 0.2482 43.5049
SKM-1 CTRP2; CTRP1 0.3158 2.0431 0.312 33.8332
Granta-519 CTRP2 0.3258 1.7147 0.3251 31.4381
WSU-DLCL2 CTRP2; CTRP1 0.3613 1.279 0.3613 42.6095
OPM-2 CTRP2 0.3713 1.3443 0.3713 31.1328
SU-DHL-8 CTRP2 0.3734 1.9543 0.3712 42.4334
KMS-26 CTRP2 0.3956 1.0273 0.3956 30.9709
KMS-34 CTRP2 0.4415 1.1912 0.4415 30.6653
NCI-H929 CTRP2 0.4454 1.1321 0.4454 30.6393
SUP-M2 CTRP2 0.4856 1.1068 0.4856 30.3714
Daudi CTRP2 0.4941 1.2108 0.4941 30.3147
NCO2 CTRP2 0.5112 1.9412 0.51 41.1777
ST486 CTRP2 0.5181 1.1727 0.5181 30.1546
BL-70 CTRP2; CTRP1 0.527 1.1049 0.527 30.1631
A4/Fukuda CTRP2 0.5428 1.2903 0.5428 29.9906
KE-97 CTRP2; CTRP1 0.5574 1.4515 0.5573 29.9609
SEM CTRP2 0.5707 1.1244 0.5707 29.8045
GA-10 CTRP2 0.5734 1.1116 0.5734 29.7864
NALM-6 CTRP2 0.5881 1.269 0.5881 29.6886
MV4-11 CTRP2 0.606 1.5365 0.606 29.5692
KMS-27 CTRP2 0.6079 1.4386 0.6079 29.5567
Ki-JK CTRP2 0.608 1.3741 0.608 40.2935
EoL-1 CTRP2 0.6351 1.354 0.6351 29.3755
HuT 78 CTRP2 0.6462 1.8658 0.6458 29.3025
RPMI-8226 CTRP2; CTRP1 0.6583 1.832 0.658 31.3785
MC116 CTRP2; CTRP1 0.6909 1.0945 0.6909 39.6202
JVM-3 CTRP2 0.6966 1.4889 0.6966 28.9656
GDM-1 CTRP2; CTRP1 0.6975 2.2887 0.694 31.1108
KMS-18 CTRP2 0.7077 1.599 0.7077 28.8916
KMS-28BM CTRP2 0.7178 2.2586 0.7148 28.8345
EB1 CTRP2 0.7423 1.9801 0.7418 28.6629
MOLP-8 CTRP2 0.823 1.9433 0.8227 28.1246
KMS-21-BM CTRP2 0.8305 1.9462 0.8303 38.2737
DoHH2 CTRP2 0.8636 1.7818 0.8632 32.0702
MOLM-13 CTRP2 0.9159 2.4983 0.9113 37.5174
KHM-1B CTRP2 0.9199 1.752 0.9199 27.4782
KMS-20 CTRP2 0.9385 2.3214 0.9366 27.3605
EJM CTRP2; CTRP1 0.9453 1.8863 0.9453 27.3789
KM-H2 CTRP2 0.9513 1.8674 0.9512 29.2154
Mono-Mac-1 CTRP2 0.9697 3.807 0.8641 27.5034
THP-1 CTRP2; CTRP1 0.9734 1.8679 0.9733 27.1922
HT CTRP2; CTRP1 0.9925 1.7966 0.9925 36.8846
NU-DHL-1 CTRP2 1.0208 2.0549 1.0206 26.8062
SU-DHL-10 CTRP2 1.0233 2.8302 1.011 36.5764
Namalwa CTRP2 1.058 1.8362 1.058 26.558
OCI-Ly19 CTRP2 1.094 3.1773 1.0651 26.4152
CA46 CTRP2 1.0978 2.0909 1.0977 26.2933
Ku812 CTRP2; CTRP1 1.1306 2.4899 1.1285 26.1524
KE-37 CTRP2 1.1565 2.1243 1.1564 35.3121
HDLM-2 CTRP2 1.1856 2.512 1.1836 25.7146
SU-DHL-5 CTRP1 1.1997 2.1192 1.1996 55.1286
OCI-Ly3 CTRP2 1.2056 2.4164 1.2046 25.5778
Kasumi-2 CTRP2 1.2109 1.9525 1.2109 25.5395
Pfeiffer CTRP2 1.2464 2.1632 1.2463 25.303
697 CTRP2 1.2723 1.9644 1.2722 25.1306
KO52 CTRP2 1.282 1.8933 1.282 25.0659
RCH-ACV CTRP2 1.2906 2.318 1.2902 34.0957
Hs 611.T CTRP2 1.2968 2.4174 1.2962 24.969
EHEB CTRP2 1.3118 2.2445 1.3116 33.9023
DB CTRP2 1.3138 2.2085 1.3137 24.8542
RL CTRP2 1.3279 1.9905 1.3279 24.7598
DND-41 CTRP2 1.3309 3.0539 1.3173 24.7855
RS4;11 CTRP2 1.3317 2.1556 1.3317 24.7344
AMO1 CTRP2; CTRP1 1.3601 2.3874 1.3598 33.5511
MHH-CALL-4 CTRP2 1.3632 3.5628 1.3138 33.6554
MOTN-1 CTRP2 1.3642 2.2792 1.3641 24.5185
SU-DHL-1 CTRP2 1.3675 1.8657 1.3675 33.3955
SUP-B15 CTRP2 1.3785 2.3874 1.3782 24.4235
PF-382 CTRP2 1.3811 2.301 1.381 24.4055
SET-2 CTRP2 1.3872 1.9766 1.3872 24.3647
HPB-ALL CTRP2 1.4096 2.0542 1.4096 24.2158
DEL CTRP2 1.415 1.8692 1.415 32.9641
P31/FUJ CTRP2 1.44 1.9137 1.44 32.7372
TALL-1 [Human adult T-ALL] CTRP2 1.4554 3.4784 1.4188 24.0336
AML-193 CTRP2 1.4638 1.9531 1.4638 23.8547
JJN-3 CTRP2 1.4688 2.0611 1.4688 23.821
MOLT-16 CTRP2 1.4768 2.0241 1.4768 32.4025
U266B1 CTRP2 1.4847 2.2185 1.4847 23.7152
ALL-SIL CTRP2 1.4879 2.292 1.4879 32.3017
JURL-MK1 CTRP2 1.5006 2.46 1.5004 32.1873
JeKo-1 CTRP2 1.5083 1.9656 1.5083 23.5582
EM-2 CTRP2 1.5128 2.0662 1.5128 32.0754
Ci-1 CTRP2 1.5238 1.9712 1.5238 23.4547
SU-DHL-4 CTRP2; CTRP1 1.5286 2.9179 1.5238 32.0434
P12-Ichikawa CTRP2 1.5346 2.1581 1.5346 31.8774
RPMI-8402 CTRP2 1.5485 2.1193 1.5485 31.7512
OCI-AML-5 CTRP2 1.5503 1.9789 1.5503 23.2784
CML-T1 CTRP2 1.5525 2.085 1.5525 31.715
HEL CTRP2 1.5589 2.0304 1.5589 19.3715
L-428 CTRP2 1.559 3.3814 1.5346 23.302
M-07e CTRP2 1.5686 2.0713 1.5686 23.1565
MOLT-3 CTRP2 1.5688 1.9107 1.5688 23.1551
LAMA-84 CTRP2 1.5976 2.693 1.5966 24.6055
F-36P CTRP2 1.6068 2.8387 1.6044 22.9098
SIG-M5 CTRP2 1.6086 1.9201 1.6086 22.8901
MOLM-16 CTRP2; CTRP1 1.609 3.8526 1.5417 31.5971
Jurkat CTRP2 1.6153 2.2506 1.6152 18.9394
L-363 CTRP2 1.6187 2.1666 1.6187 24.4517
KMS-12-BM CTRP2 1.6238 2.2112 1.6238 22.7883
TF-1 CTRP2 1.6245 2.0699 1.6245 22.7836
A3/Kawakami CTRP2 1.626 2.0077 1.626 22.7736
L-540 CTRP2 1.6292 2.2075 1.6292 31.0188
HD-MY-Z CTRP2 1.636 2.0907 1.636 22.7072
HL-60 CTRP2 1.6413 2.1438 1.6413 22.6722
SUP-T11 CTRP2 1.6672 2.4273 1.6672 22.4994
BV-173 CTRP2 1.7004 2.6199 1.7002 23.8691
OCI-M1 CTRP2 1.7119 2.2345 1.7119 22.2015
MOLP-2 CTRP2 1.7202 3.1235 1.7132 23.7519
MOLT-13 CTRP2 1.7209 3.9164 1.6515 23.9736
K-562 CTRP2 1.7721 2.5185 1.7721 21.8006
SUP-T1 CTRP2 1.7872 2.9957 1.7843 23.2591
LP-1 CTRP2; CTRP1 1.7911 2.7417 1.7907 21.7507
HEL 92.1.7 CTRP2 1.8924 2.5576 1.8924 20.9992
MM1.S CTRP2 1.8967 2.7022 1.8966 20.9705
U-937 CTRP2; CTRP1 2.0235 2.9507 2.0229 20.2045
Mono-Mac-6 CTRP2 2.0843 8.4027 0.534 33.3201
SUP-HD1 CTRP2 2.1761 3.8547 2.1411 19.2269
MOLM-6 CTRP2 2.2476 3.2636 2.2454 25.4119
P3HR-1 CTRP2; CTRP1 2.3472 4.177 2.2854 24.8817
Karpas-299 CTRP2 2.3618 3.1271 2.3615 19.1485
SR CTRP2 2.3679 4.2295 2.2988 19.3557
RPMI-6666 CTRP2 2.4959 3.7664 2.482 17.0248
Raji CTRP2 2.6448 3.161 2.6448 17.1275
OCI-Ly10 CTRP2; CTRP1 2.6485 3.846 2.6356 16.0859
Karpas-422 CTRP2 2.695 3.9534 2.6764 15.7147
Toledo CTRP2 2.7368 5.3863 2.425 16.4789
KCL-22 CTRP2 2.7532 4.4259 2.6816 16.6151
KYO-1 CTRP2 2.7643 3.7238 2.7596 15.2063
NB4 CTRP2 2.8019 3.6077 2.8002 16.0123
NOMO-1 CTRP2; CTRP1 2.8473 3.6129 2.8461 15.7733
OCI-AML-2 CTRP2 2.8487 3.509 2.8483 15.6739
Kasumi-1 CTRP2 2.8619 4.4132 2.8005 14.7488
ME1 CTRP2 2.8731 4.1037 2.8503 15.5801
MHH-CALL-3 CTRP2 2.9045 7.9196 1.5844 20.5676
Reh CTRP2 3.3185 4.2796 3.3019 12.379
CMK CTRP2 4.462 4.8748 4.4458 3.9354
KMM-1 CTRP2 4.5035 11.4862 1.3623 21.5167
Karpas-620 CTRP2 6.1562 12.236 2.3279 10.0345
REC-1 CTRP2 7.9313 18.2768 0.6524 12.8844
⏷ Show the Full List of 148 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 1.2106 2.9848 1.1967 25.588
TE8 CTRP2 1.9417 3.2248 1.9359 20.6901
TE-10 CTRP2 1.3408 2.3417 1.3386 19.5523
TE-5 CTRP2 1.4697 2.2811 1.4696 23.8154
TE-9 CTRP2 1.4822 1.9739 1.4822 23.7322
KYSE-140 CTRP2; CTRP1 1.5289 2.5362 1.5285 23.4959
KYSE-30 CTRP2 1.5578 1.9957 1.5578 23.2282
KYSE-450 CTRP2; CTRP1 1.5898 2.5083 1.5896 23.0901
KYSE-180 CTRP2 1.615 2.1466 1.615 22.8472
OE21 CTRP2 1.6454 3.3975 1.6233 22.7188
KYSE-150 CTRP2 1.7503 2.2469 1.7503 21.946
KYSE-510 CTRP2 1.7565 2.5637 1.7564 21.9047
TE-11 CTRP2 1.8182 2.8527 1.8172 21.497
KYSE-410 CTRP2; CTRP1 2.1477 3.6681 2.1274 20.8306
TE-14 CTRP2 2.3096 3.983 2.2687 18.3579
TE-4 CTRP2 2.5912 3.8278 2.577 16.3914
TE-6 CTRP2 2.6286 4.3209 2.5644 16.3128
COLO 680N CTRP2 2.6333 4.3928 2.558 22.2487
OE33 CTRP2 2.9487 4.4065 2.8946 14.146
KYSE-70 CTRP2 3.8658 5.2241 3.7049 8.4227
EC-GI-10 CTRP2 4.2749 8.3477 2.7146 11.3815
KYSE-520 CTRP2 4.4543 6.6812 3.694 6.928
OE19 CTRP2 4.5128 5.0035 4.4748 3.6735
TE-1 CTRP2 5.0414 6.7631 4.1825 3.6285
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.9136 4.9867 3.8256 7.8399
KP-3 CTRP2; CTRP1 1.2753 3.1804 1.2535 25.2553
BxPC-3 CTRP2 1.4927 2.2206 1.4927 32.2585
KP-4 CTRP2 1.5382 2.0828 1.5382 31.845
Panc 08.13 CTRP2 1.6907 2.5018 1.6906 22.3431
SW1990 CTRP2 1.6928 4.4017 1.54 22.8527
SU.86.86 CTRP2 1.7302 2.3262 1.7302 22.0798
MIA PaCa-2 CTRP2 1.7478 2.3202 1.7478 21.9623
DAN-G CTRP2 1.8305 2.8833 1.8293 21.4155
Hs 766T CTRP2 1.8393 3.6219 1.8086 21.456
Panc 03.27 CTRP2; CTRP1 1.8403 2.4511 1.8403 21.4221
HuP-T4 CTRP2; CTRP1 1.958 2.6806 1.9579 20.6389
QGP-1 CTRP2; CTRP1 2.0057 4.1196 1.9284 28.0493
Capan-1 CTRP2 2.4437 4.1605 2.3896 17.5093
KP-2 CTRP2 2.4649 4.8768 2.2733 17.8507
PSN1 CTRP2 2.5158 4.2124 2.4595 17.0369
Panc 10.05 CTRP2; CTRP1 2.5196 3.2897 2.5191 16.9026
Panc 04.03 CTRP2 2.5458 4.4758 2.4492 16.9766
PaTu 8988s CTRP2 2.5491 4.7129 2.404 17.1252
L3.3 CTRP2 2.6531 4.5615 2.549 16.2884
PANC-1 CTRP2 2.6678 4.1932 2.624 15.9815
CFPAC-1 CTRP2; CTRP1 2.8744 4.2898 2.8324 20.0081
HPAF-II CTRP2 2.8907 4.4548 2.8247 14.5732
SUIT-2 CTRP2; CTRP1 2.9925 4.7953 2.8699 14.1768
PaTu 8902 CTRP2; CTRP1 3.1731 4.1595 3.1598 12.5959
SNU-410 CTRP2 3.3149 6.4513 2.6481 13.9994
PaTu 8988t CTRP2 3.4886 4.566 3.4492 10.4988
Panc 05.04 CTRP2 3.5613 4.0084 3.561 9.8818
AsPC-1 CTRP2 3.6106 5.7874 3.2286 10.9467
HuP-T3 CTRP2 3.6634 8.1837 2.2148 14.84
Capan-2 CTRP2; CTRP1 3.8187 6.9772 2.9391 11.6219
Panc 02.03 CTRP2 3.8836 4.8236 3.8303 7.9164
YAPC CTRP2 3.9146 4.6928 3.8866 7.6219
HPAC CTRP2; CTRP1 3.9945 5.4664 3.7652 7.9123
PK-59 CTRP2 4.0254 5.4037 3.817 7.5406
TCC-Pan2 CTRP2 4.0646 5.3264 3.8867 7.1659
SNU-213 CTRP2 4.3099 5.3055 4.1589 7.4133
PK-45H CTRP2 5.086 7.2038 3.9991 4.3139
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.8106 23.5573 -1.2921 17.5391
RPMI-7951 CTRP2 0.6605 1.2344 0.6605 39.817
Hs 294T CTRP2 1.5215 1.9261 1.5215 23.4699
Mel Ho CTRP2 1.5445 2.0616 1.5445 23.3165
CJM [Human melanoma] CTRP2 1.6525 2.1774 1.6525 22.5976
WM983B CTRP2 1.6672 2.9131 1.6643 22.5092
WM115 CTRP2 1.7715 4.0218 1.6909 22.0783
HT-144 CTRP2 1.8009 2.9007 1.7994 21.6137
A-375 CTRP2; CTRP1 1.8696 3.2267 1.8626 21.2505
SK-MEL-1 CTRP2; CTRP1 1.9116 3.1578 1.9072 20.9619
WT2-iPS CTRP2 1.9416 3.3597 1.9312 20.706
MeWo CTRP2 1.9497 3.2562 1.9432 20.6393
IGR-37 CTRP2 2.0946 3.274 2.0902 19.6666
G-361 CTRP2; CTRP1 2.1322 3.0695 2.1313 19.4821
Hs 936.T CTRP2; CTRP1 2.3402 2.9162 2.3401 18.0951
SK-MEL-5 CTRP2; CTRP1 2.4926 3.0743 2.4926 17.0803
IGR-1 CTRP2 2.6491 4.6443 2.5277 16.3758
COLO 741 CTRP2; CTRP1 2.9912 5.4599 2.6814 20.253
IGR-39 CTRP2 3.0537 5.1841 2.8322 14.042
WM88 CTRP2 3.1522 4.628 3.0763 12.8662
LOX-IMVI CTRP2 3.1691 4.2625 3.1467 12.5689
Hs 944.T CTRP2; CTRP1 3.2252 4.1229 3.2162 16.6736
RVH-421 CTRP2 3.2778 4.4342 3.2424 11.8891
WM266-4 CTRP2 3.3084 4.5977 3.2505 11.763
Hs 895.T CTRP2 3.3743 4.5061 3.3355 11.2583
Hs 852.T CTRP2; CTRP1 3.3909 4.3836 3.3689 11.1756
UACC-257 CTRP2 3.5106 4.7273 3.4452 10.4424
COLO 829 CTRP2 3.5908 6.4169 2.9499 12.0819
SK-MEL-28 CTRP2; CTRP1 3.6178 4.3262 3.6106 9.6155
WM1799 CTRP2 3.7219 4.1606 3.7214 8.8124
SK-MEL-30 CTRP2 3.7733 4.4857 3.7607 8.5106
COLO 800 CTRP2 3.7994 4.9166 3.7183 8.5751
IPC-298 CTRP2 3.8274 4.4889 3.817 8.1428
MDA-MB-435S CTRP2 3.8856 5.6376 3.5797 8.8363
Hs 688(A).T CTRP2 4.0413 7.2085 3.0441 10.5673
SK-MEL-31 CTRP2 4.2358 6.5256 3.5557 8.0155
COLO 792 CTRP2 4.3452 5.1375 4.254 4.9811
K029AX CTRP2 4.3544 4.9281 4.3197 4.7161
SK-MEL-2 CTRP2 4.3699 8.5283 2.7127 11.1793
SK-MEL-24 CTRP2 4.4678 7.6915 3.2142 8.8826
HMCB CTRP2 4.5687 4.8909 4.5577 3.2063
Hs 940.T CTRP2 4.5985 14.2976 0.0411 20.8416
A101D CTRP2 4.6014 5.178 4.5188 3.248
SK-MEL-3 CTRP2 4.6857 5.5795 4.4403 3.3284
UACC-62 CTRP2 4.7182 5.2287 4.6254 2.5129
A2058 CTRP2 4.9213 5.4617 4.726 1.5967
Mel JuSo CTRP2 5.3647 7.9877 3.8304 4.8394
WM793 CTRP2 5.8292 8.4414 3.9471 3.2996
Hs 839.T CTRP2 6.8505 7.81 4.7382 0.0461
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 2.5367 5.2879 2.2375 17.7625
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 0.6055 1.0013 0.6055 29.5725
SK-N-DZ CTRP2 0.7561 1.4148 0.7561 28.5695
NH-6 CTRP2 1.0783 2.3223 1.0773 26.426
SK-N-BE(2) CTRP2 1.1083 2.3661 1.1071 26.2268
MHH-NB-11 CTRP2 1.1914 2.6992 1.1864 35.0172
SiMa CTRP2 1.3522 2.6569 1.3499 33.5447
SK-N-AS CTRP2 1.388 3.1207 1.3729 24.4099
SK-N-SH CTRP2 1.4044 2.3301 1.4042 24.251
CHP-126 CTRP2 1.5447 2.3133 1.5446 31.7864
SK-N-FI CTRP2 1.5583 2.1275 1.5583 23.2247
Kelly CTRP2 1.6652 2.3166 1.6652 24.1193
CHP-212 CTRP2 1.7196 3.4392 1.6975 22.2243
KP-N-YN CTRP2 2.8103 10.6001 0.2395 24.3327
NB1 CTRP2 3.0368 3.9376 3.0307 14.3515
KP-N-SI9s CTRP2 3.4105 4.0618 3.4081 11.6705
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 0.8552 2.4475 0.8507 38.0686
SNU-245 CTRP2 1.43 4.4016 1.255 33.5961
HuH-28 CTRP2 1.4929 2.1518 1.4928 23.6609
SNU-478 CTRP2 1.562 2.1208 1.562 23.2003
HuCC-T1 CTRP2 1.5637 2.565 1.5633 31.6154
SNU-308 CTRP2 1.8891 3.0361 1.8867 21.029
SNU-869 CTRP2 2.7637 4.9389 2.5834 15.8224
SNU-1196 CTRP2 4.3504 7.1382 3.3748 11.5616
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-78 CTRP2 -0.6171 5.3115 -1.2091 41.7848
A-673 CTRP2 0.8793 1.533 0.8793 27.7482
MHH-ES-1 CTRP2 1.0511 1.9143 1.0511 26.6038
SK-N-MC CTRP2 1.2867 1.864 1.2867 25.0341
SK-ES-1 CTRP2 1.4454 2.0849 1.4454 23.9769
U2OS CTRP2; CTRP1 1.5334 2.5808 1.5328 23.4664
HOS CTRP2 1.5696 2.0766 1.5696 23.1493
SaOS-2 CTRP2 1.5924 2.1577 1.5924 22.9976
TC71 CTRP2 1.7602 2.2462 1.7602 21.8795
MG-63 CTRP2 1.8903 3.8974 1.8342 21.2026
SJSA-1 CTRP2 2.4104 3.2768 2.4094 17.5512
G-292 clone A141B1 CTRP2 2.4812 5.6913 2.047 18.6278
Hs 888.T CTRP2 3.3426 10.2223 0.9293 20.5934
SW1353 CTRP2 3.4055 4.1707 3.3992 14.9139
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-157 CTRP2 1.3653 4.4369 1.1773 25.1552
AU565 CTRP2 1.4044 6.4393 0.6196 26.9808
HCC1954 CTRP2 1.4993 2.2101 1.4993 23.618
HMC-1-8 CTRP2 1.563 1.9877 1.563 23.1935
HCC1806 CTRP2 1.5823 2.1005 1.5823 23.065
DU4475 CTRP2 1.6377 2.1228 1.6377 22.6959
Hs 578T CTRP2 1.6591 3.3539 1.6402 22.6166
CAL-148 CTRP2 1.6681 3.4884 1.6404 22.5863
SK-BR-3 CTRP2 1.7196 4.1691 1.612 22.5171
CAL-51 CTRP2 1.7332 2.5628 1.733 22.0603
MDA-MB-453 CTRP2 1.7897 3.15 1.7832 21.7049
HCC38 CTRP2 1.7968 3.5298 1.7716 21.7205
BT-20 CTRP2 1.8118 4.0098 1.7358 21.794
HCC1500 CTRP2 1.8145 2.7209 1.8142 21.5193
CAL-120 CTRP2 1.8611 3.9383 1.798 29.2012
Hs 578Bst CTRP2 1.9286 3.3186 1.9195 20.7886
EFM-192A CTRP2 2.213 4.0657 2.1563 19.0552
T-47D CTRP2 2.3833 4.6839 2.2302 18.2571
CAL-85-1 CTRP2 2.4944 4.7617 2.3333 17.546
HCC1419 CTRP2 2.6837 5.1253 2.4455 16.5631
HCC2218 CTRP2 2.7207 5.5363 2.3589 16.7704
MDA-MB-468 CTRP2 2.8059 5.2684 2.5368 15.8635
HCC1937 CTRP2 2.9206 5.4325 2.6101 15.2532
BT-474 CTRP2 2.9807 5.4886 2.6569 14.9034
BT-549 CTRP2 3.0523 4.8949 2.9093 13.7685
HCC1395 CTRP2 3.6096 6.1445 3.0843 11.506
HCC1143 CTRP2 3.7309 6.8887 2.8846 11.9782
ZR-75-1 CTRP2 4.0543 4.9308 3.9926 6.8095
HDQ-P1 CTRP2 4.1453 7.3677 3.0688 13.9185
JIMT-1 CTRP2 4.188 6.6968 3.4286 11.7887
HCC202 CTRP2 4.227 6.1136 3.7358 7.3127
CAMA-1 CTRP2 4.5364 14.2934 -0.6464 24.4745
ZR-75-30 CTRP2 4.6238 8.5283 2.9406 9.6868
MCF-7 CTRP2; CTRP1 4.7567 9.2213 2.7208 14.1027
KPL-1 CTRP2 5.0496 7.0598 4.041 5.7359
MDA-MB-361 CTRP2 5.2566 10.1242 2.6791 9.5249
HCC1428 CTRP2 5.5909 9.1691 3.4179 5.8512
MDA-MB-231 CTRP2 7.2354 9.23 4.3755 0.5553
BT 145 CTRP2 1.4571 1.9301 1.4571 23.8992
BT 139 CTRP2 1.5169 1.905 1.5169 23.5008
BT 239 CTRP2 1.5451 1.9135 1.5451 23.3128
BT164 CTRP2 1.5633 1.9632 1.5633 23.1917
BT 231 CTRP2 1.6365 3.6748 1.5906 22.8585
BT 504 CTRP2 1.6498 2.0112 1.6498 22.615
BT 416 CTRP2 1.6512 2.2745 1.6512 22.6059
BT 248 CTRP2 1.6516 3.034 1.6459 22.6223
BT 159 CTRP2 1.7058 2.1046 1.7058 22.2424
BT 428 CTRP2 1.71 2.3422 1.71 22.2142
BT 271 CTRP2 1.7286 2.658 1.7283 22.0914
BT 245 CTRP2 1.8034 2.6105 1.8033 21.5922
BT 482 CTRP2 1.81 2.4867 1.81 21.548
BT 216 CTRP2 1.8202 2.7023 1.8199 21.4812
BT 187 CTRP2 1.8503 2.7973 1.8498 21.2811
BT 330 CTRP2 1.887 2.8349 1.8864 21.0371
BT 172 CTRP2 1.9623 3.5937 1.9392 20.6109
BT 359 CTRP2 1.9713 3.1202 1.9684 20.4829
BT 112 CTRP2 1.9796 3.0404 1.978 20.4234
BT 333 CTRP2 2.0904 3.4836 2.0785 19.7197
BT 440 CTRP2 2.4994 4.0695 2.46 17.0883
BT 228 CTRP2 2.503 4.5871 2.381 17.3504
BT 131 CTRP2 2.6548 3.579 2.6519 15.9296
BT 232 CTRP2 2.9429 3.8881 2.9364 14.0222
BT147 CTRP2 2.9657 4.8542 2.8249 14.3368
BT 286 CTRP2 3.1321 4.0714 3.1225 12.7722
BT 422 CTRP2 3.1665 4.5904 3.0988 12.7422
BT 179 CTRP2 3.283 4.4148 3.2503 11.8452
BT 340 CTRP2 3.4885 4.1086 3.4862 10.3731
BT 444 CTRP2 3.8391 4.4174 3.8338 8.0476
BT 224 CTRP2 4.1459 4.9632 4.0847 6.1982
BT 328 CTRP2 4.4176 5.0375 4.3623 4.3691
BT 320 CTRP2 5.569 8.0029 3.9763 3.5728
BT 498 CTRP2 5.8101 7.6257 4.3224 1.8359
⏷ Show the Full List of 72 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 1.6314 1.9518 1.6314 22.7377
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AM-38 CTRP2 -8.5772 3.9952 -9.5484 73.8936
SNU-466 CTRP2 1.048 1.8716 1.0479 26.6249
D283 Med CTRP2 1.1771 2.0421 1.177 25.7647
LN-18 CTRP2 1.2745 1.8582 1.2745 20.0163
LN-229 CTRP2; CTRP1 1.3088 2.2247 1.3087 24.9597
SF539 CTRP2 1.6276 2.0758 1.6276 22.7629
Daoy CTRP2 1.644 2.6273 1.6436 22.6554
Hs 683 CTRP2 1.6714 2.1405 1.6714 22.4714
SNU-626 CTRP2 1.6769 2.9416 1.6736 30.6004
U-118MG CTRP2 1.6994 2.3512 1.6993 22.2852
SF126 CTRP2 1.7359 2.3133 1.7359 22.0415
SF295 CTRP2; CTRP1 1.8322 3.5324 1.8087 21.5548
GB-1 CTRP2 1.8473 3.0162 1.8447 21.3084
KNS-60 CTRP2 1.9478 2.6797 1.9478 20.63
SNU-738 CTRP2 1.9526 3.6646 1.9237 28.2135
42-MG-BA CTRP2 1.9921 3.5428 1.9736 20.3967
DK-MG CTRP2 2.1535 3.2294 2.1509 19.2683
CCF-STTG1 CTRP2 2.4359 4.235 2.3709 17.5991
M059K CTRP2 2.6379 4.0162 2.6114 16.1217
ONS-76 CTRP2 2.6608 4.0174 2.6353 21.7663
SNU-1105 CTRP2 2.871 3.7894 2.8278 12.3203
KNS-42 CTRP2 2.8842 4.9289 2.7175 14.9717
SW1088 CTRP2 2.9034 4.1739 2.8755 14.3577
CAS-1 CTRP2 2.9994 5.1102 2.7943 19.5538
Becker CTRP2 3.0427 5.3035 2.784 14.2513
SNB-75 CTRP2 3.0869 5.8242 2.654 14.6075
GMS-10 CTRP2 3.1703 5.5594 2.8385 13.6748
SF268 CTRP2 3.2149 5.9331 2.7503 13.8799
YH-13 CTRP2 3.2555 5.0592 3.0881 12.5041
T98G CTRP2 3.4467 4.9643 3.322 11.0784
TM-31 CTRP2 3.4581 4.7243 3.389 10.8053
KALS-1 CTRP2 3.4769 5.2606 3.2702 11.973
A-172 CTRP2 3.5454 5.3375 3.3201 10.7887
GOS-3 CTRP2 3.565 5.3347 3.3422 10.6491
SNU-201 CTRP2 3.5751 5.3708 3.3412 14.483
GaMG CTRP2; CTRP1 3.7039 4.5302 3.684 9.0854
KNS-81 CTRP2 4.03 5.0841 3.9263 7.1222
U-87MG ATCC CTRP2 4.0536 6.8328 2.6865 8.8861
8-MG-BA CTRP2 4.2095 4.9378 4.16 5.733
YKG-1 CTRP2 4.6075 7.6036 3.3847 7.868
DBTRG-05MG CTRP2 5.0467 6.7085 4.2143 3.7335
SNU-489 CTRP2 5.0477 6.687 4.2258 4.682
U-251MG CTRP2 5.4109 8.2142 3.7536 4.758
KG-1-C CTRP2 6.7073 7.7737 4.7002 0.1035
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP2; CTRP1 0.6693 1.2475 0.6693 29.2161
HEC-6 CTRP2; CTRP1 0.9848 1.6987 0.9848 29.0491
RL95-2 CTRP2 1.3734 1.9752 1.3734 33.3418
HEC-265 CTRP2; CTRP1 1.3816 2.0846 1.3816 24.4747
JHUEM-2 CTRP2; CTRP1 1.4878 2.021 1.4878 25.4631
JHUEM-1 CTRP2 1.5071 1.8629 1.5071 23.5661
MFE-296 CTRP2 1.5725 2.7014 1.5713 23.1343
ESS-1 CTRP2 1.6176 2.1155 1.6176 22.8297
JHUEM-7 CTRP2 1.6238 2.3859 1.6238 22.7885
JHUEM-3 CTRP2 1.7778 3.5426 1.7507 21.8535
HEC-50B CTRP2 2.2892 4.4237 2.1814 25.5255
HEC-59 CTRP2; CTRP1 2.3906 3.505 2.3854 19.0441
AN3-CA CTRP2 2.4011 4.6849 2.2493 18.1342
HEC-108 CTRP2; CTRP1 2.6881 3.7578 2.6807 16.9308
MFE-319 CTRP2; CTRP1 2.7425 4.2044 2.7028 15.5514
HEC-251 CTRP2; CTRP1 2.7668 4.8415 2.6133 16.9126
KLE CTRP2; CTRP1 3.5063 5.2806 3.2991 11.0673
HEC-1-B CTRP2 4.4828 7.8469 2.5262 8.7002
EFE-184 CTRP2 4.5787 7.0064 3.6526 6.8158
HEC-1-A CTRP2 4.7105 7.7502 3.4041 7.5675
EN CTRP2 4.9321 5.7608 4.5888 2.1435
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 1.4975 2.067 1.4975 25.3937
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-909 CTRP2 0.5459 1.1525 0.5459 40.8574
KMRC-3 CTRP2 1.4433 2.9821 1.4352 24.0181
UO-31 CTRP2 1.5439 2.7138 1.5424 23.3257
CAL-54 CTRP2 1.6024 2.2307 1.6024 22.9311
TUHR4TKB CTRP2 1.661 2.88 1.6585 30.7414
VMRC-RCW CTRP2; CTRP1 1.9091 2.8134 1.9087 20.9656
RCC10RGB CTRP2; CTRP1 2.0991 3.0664 2.098 19.7032
KMRC-2 CTRP2 2.1915 4.3954 2.0811 19.3841
786-O CTRP2 2.2537 3.2136 2.2522 18.5972
OS-RC-2 CTRP2 2.9363 4.7636 2.814 19.7224
TUHR10TKB CTRP2 3.1065 4.0047 3.0994 17.6335
769-P CTRP2 3.1953 4.3329 3.1669 12.4149
KMRC-20 CTRP2 3.5277 5.0094 3.3986 14.3897
VMRC-RCZ CTRP2 4.3769 7.3099 3.3165 8.6628
KMRC-1 CTRP2 4.5233 5.0135 4.4838 3.6092
SNU-1272 CTRP2 4.6744 6.5846 3.9477 5.3776
ACHN CTRP2 4.6854 5.2046 4.5997 2.7029
Caki-1 CTRP2 5.0008 6.8356 4.1122 4.0031
Caki-2 CTRP2 5.0146 6.6938 4.1947 3.6297
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C5 CTRP2; CTRP1 0.2526 1.6325 0.252 31.9912
T84 CTRP2 0.3705 2.0872 0.3666 31.1509
HCT 116 CTRP2; CTRP1 1.0583 2.0811 1.0581 26.6272
LS180 CTRP2; CTRP1 1.0615 1.9929 1.0615 26.6055
KM12 CTRP2; CTRP1 1.1102 2.6765 1.1046 28.1751
CW-2 CTRP2; CTRP1 1.1681 2.7756 1.161 35.3235
COLO 320 CTRP2; CTRP1 1.1867 3.0824 1.1675 25.8362
SNU-81 CTRP1 1.421 2.3305 1.4209 51.9689
SNU-175 CTRP2; CTRP1 1.4369 3.7451 1.3721 33.1436
SW48 CTRP2; CTRP1 1.5624 2.0742 1.5624 31.7153
SNU-C1 CTRP2 1.578 2.2128 1.578 23.0937
LS513 CTRP2; CTRP1 1.6058 2.091 1.6058 31.3217
LS1034 CTRP2 1.6229 2.2034 1.6229 22.7945
NCI-H747 CTRP2 1.6487 3.5214 1.6175 22.7273
CL-34 CTRP1 1.6575 3.0183 1.6525 48.6008
SNU-C4 CTRP2; CTRP1 1.671 2.0822 1.671 22.5486
SNU-1033 CTRP2 1.6828 4.257 1.5569 22.8258
OUMS-23 CTRP2 1.6878 2.1358 1.6878 30.486
HCT 15 CTRP2 1.733 2.5188 1.7329 22.0615
COLO 678 CTRP2; CTRP1 1.8147 3.4634 1.7951 21.6582
LoVo CTRP2; CTRP1 1.827 3.0499 1.8236 21.5218
DLD-1 CTRP2; CTRP1 1.8294 2.2609 1.8294 29.2932
HT115 CTRP2; CTRP1 1.8638 2.6714 1.8636 21.2662
GP2d CTRP2; CTRP1 1.8833 2.9947 1.8814 21.142
NCI-H508 CTRP2; CTRP1 1.9257 3.0132 1.924 22.3465
CCK-81 CTRP2 1.9782 3.8748 1.9301 22.0596
SW948 CTRP2; CTRP1 1.9796 2.6386 1.9796 20.4946
SW480 CTRP1 2.0226 4.4958 1.8803 43.9551
COLO205 CTRP2; CTRP1 2.1536 2.8016 2.1536 26.3528
SNU-C2A CTRP2; CTRP1 2.2596 3.739 2.2389 18.7007
C2BBe1 CTRP2; CTRP1 2.2666 3.393 2.2622 18.5991
RKO CTRP2; CTRP1 2.3827 3.3354 2.3809 19.0886
CL-11 CTRP2 2.3892 4.1086 2.3383 19.1364
SW620 CTRP2; CTRP1 2.4067 3.557 2.4001 17.6743
SNU-1040 CTRP1 2.5206 4.0529 2.4849 36.5029
LS123 CTRP2; CTRP1 2.5249 3.4138 2.5234 16.8706
SNU-407 CTRP2 2.5885 3.4899 2.5864 16.3684
SK-CO-1 CTRP2; CTRP1 2.624 3.77 2.6143 22.1296
MDST8 CTRP2; CTRP1 2.6619 3.3822 2.6614 15.9553
HCT 8 CTRP2; CTRP1 2.7046 4.2373 2.6584 15.8255
LS411N CTRP2; CTRP1 2.8719 3.993 2.858 19.9007
CL-40 CTRP1 2.9413 4.4381 2.883 30.6695
HT-55 CTRP2; CTRP1 2.987 4.0373 2.9746 13.8313
SNU-61 CTRP1 3.0125 4.1055 2.9965 29.3495
SNU-503 CTRP2 3.0518 5.044 2.87 13.9109
NCI-H716 CTRP2 3.0739 4.5023 3.014 13.3318
HT-29 CTRP2; CTRP1 3.32 5.3155 3.0853 13.2894
HCC-56 CTRP2 3.3944 5.5594 3.0808 12.1201
RCM-1 [Human ESC] CTRP2; CTRP1 3.6552 5.0051 3.5413 9.7389
COLO201 CTRP2 3.6807 4.1045 3.6804 9.7348
SW1417 CTRP2 4.083 8.8052 2.313 13.4615
SW403 CTRP1 5.1959 7.6494 3.876 10.081
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP2; CTRP1 0.8723 2.8896 0.8533 38.0568
SNU-886 CTRP2 1.132 8.0459 -0.3011 30.7701
HLF CTRP2 1.5187 1.9566 1.5187 23.4886
JHH-2 CTRP2 1.576 2.1436 1.576 23.107
Li-7 CTRP2 1.6105 2.5878 1.6101 31.1901
SNU-387 CTRP2 1.6908 3.2705 1.6773 22.3873
SNU-182 CTRP2 1.7199 4.7872 1.4831 22.9685
SNU-423 CTRP2 1.7714 3.4217 1.7524 21.8689
PLC/PRF/5 CTRP2 2.2348 3.9868 2.1892 18.872
SNU-449 CTRP2; CTRP1 2.2683 3.0829 2.2679 18.5743
SNU-761 CTRP2 2.3572 3.1179 2.3569 17.9036
SNU-878 CTRP2 2.8411 4.3438 2.7887 20.2539
JHH-6 CTRP2; CTRP1 3.0753 3.9058 3.0713 13.2157
JHH-5 CTRP2 3.2355 4.4469 3.1956 12.1864
Hep-G2 CTRP2; CTRP1 3.5001 4.232 3.4939 10.3955
JHH-1 CTRP2 3.736 5.0377 3.6184 9.1278
Hep 3B2.1-7 CTRP2 3.7923 4.6376 3.7637 11.5046
HuH-1 CTRP2 4.422 5.099 4.3495 4.402
JHH-4 CTRP2 4.5342 5.442 4.3447 4.102
SNU-475 CTRP2 4.5365 5.3046 4.4024 3.873
SK-HEP-1 CTRP2 4.9283 5.9379 4.4976 2.5329
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 159 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1963 CTRP1 -0.032 2.4652 -0.0575 70.1345
NCI-H1048 CTRP1 0.355 1.0964 0.355 67.1881
SCLC-21H CTRP1 0.4167 1.0276 0.4167 66.3157
NCI-H810 CTRP2; CTRP1 0.4506 1.4547 0.4505 30.6718
NCI-H2029 CTRP2; CTRP1 0.5425 1.587 0.5424 30.06
SHP-77 CTRP2; CTRP1 0.7226 1.3355 0.7226 39.3325
NCI-H596 CTRP1 0.7271 1.333 0.7271 61.8822
NCI-H1341 CTRP2 0.7946 1.7758 0.7946 28.3128
DMS 53 CTRP2 0.9334 2.2921 0.9318 27.3933
NCI-H1836 CTRP1 0.9907 2.5668 0.9858 57.9815
VMRC-LCD CTRP2; CTRP1 1.0936 3.4931 1.0372 26.5816
DV-90 CTRP2; CTRP1 1.1075 2.4927 1.1051 26.3071
ChaGo-K-1 CTRP2; CTRP1 1.1221 3.1071 1.0993 26.2783
COR-L23 CTRP1 1.1485 1.9888 1.1485 55.8612
COR-L51 CTRP2; CTRP1 1.1667 3.3566 1.1274 26.0373
NCI-H1734 CTRP2 1.1957 2.1735 1.1943 20.5821
NCI-H82 CTRP1 1.2012 2.2531 1.2009 55.0982
NCI-H1573 CTRP2; CTRP1 1.2196 2.4689 1.2183 27.3797
NCI-H446 CTRP2 1.2771 3.4945 1.2299 25.2571
NCI-H1781 CTRP1 1.2834 2.3363 1.283 53.9307
COR-L95 CTRP2 1.2958 2.1361 1.2958 24.9737
NCI-H520 CTRP2 1.3202 3.1113 1.3035 24.867
NCI-H1155 CTRP2 1.3436 2.2497 1.3435 33.6127
NCI-H1105 CTRP2; CTRP1 1.362 3.0839 1.3481 24.652
NCI-H1694 CTRP2; CTRP1 1.362 2.6705 1.3597 24.6131
NCI-H211 CTRP2 1.3939 2.624 1.3922 24.3258
DMS 79 CTRP2 1.4093 2.12 1.4093 24.2176
NCI-H2106 CTRP2 1.4107 4.9904 1.0934 34.3551
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 1.4235 1.9798 1.4235 32.9753
NCI-H1568 CTRP2; CTRP1 1.4261 2.6465 1.4245 24.1844
DMS 273 CTRP2; CTRP1 1.4624 2.2248 1.4624 23.9373
NCI-H2196 CTRP2 1.5106 2.3224 1.5106 23.5426
SK-MES-1 CTRP2 1.5774 3.2497 1.5615 23.1509
HCC44 CTRP2; CTRP1 1.6007 2.4474 1.6006 23.0173
RERF-LC-A1 CTRP2 1.6136 2.0061 1.6136 22.8566
HCC2279 CTRP2 1.624 2.2898 1.624 22.7871
NCI-H292 CTRP2 1.6275 2.1651 1.6275 22.7639
HCC1438 CTRP2 1.6295 2.1781 1.6295 22.7505
NCI-H2087 CTRP2 1.6451 3.0583 1.6387 24.2859
COLO 668 CTRP1 1.6475 3.0585 1.6412 48.7412
NCI-H1092 CTRP2 1.6483 3.2349 1.6353 22.6686
HCC1588 CTRP2 1.6577 2.143 1.6577 22.5624
NCI-H727 CTRP2; CTRP1 1.6652 3.6671 1.6223 30.9777
NCI-H526 CTRP2 1.6688 2.9105 1.6659 22.4986
NCI-H358 CTRP2; CTRP1 1.6695 2.2202 1.6695 30.7436
Lu-99 CTRP2; CTRP1 1.6732 2.0938 1.6732 30.7097
NCI-H1563 CTRP2 1.6817 2.2502 1.6817 22.4031
NCI-H647 CTRP2 1.6934 3.3819 1.6741 22.3895
HCC1833 CTRP2; CTRP1 1.7204 2.3826 1.7203 22.2203
LC-1/sq-SF CTRP2; CTRP1 1.7233 2.8406 1.7219 22.2054
NCI-H1581 CTRP2 1.7236 3.196 1.7142 30.2036
NCI-H23 CTRP2; CTRP1 1.7263 3.0268 1.722 22.195
DMS 114 CTRP2 1.7281 2.6341 1.7278 22.0946
NCI-H2009 CTRP2; CTRP1 1.7301 2.9691 1.727 30.2083
MOR/CPR CTRP2 1.7351 2.105 1.7351 22.0468
LCLC-97TM1 CTRP2; CTRP1 1.7382 3.467 1.7154 23.7594
NCI-H522 CTRP2; CTRP1 1.7461 2.9231 1.7439 22.0563
NCI-H69 CTRP2 1.7699 4.3087 1.6415 22.2544
NCI-H1385 CTRP2 1.7987 4.5091 1.6328 22.1937
HCC366 CTRP2 1.799 3.8672 1.7409 29.7417
NCI-H1703 CTRP2 1.7993 2.5748 1.7993 21.6193
NCI-H1339 CTRP2 1.8137 2.9053 1.8122 21.5285
LK2 CTRP2 1.856 2.2612 1.856 21.2417
NCI-H1915 CTRP2; CTRP1 1.8802 2.9594 1.8786 21.1618
HCC15 CTRP2; CTRP1 1.9073 3.0537 1.9048 28.5982
NCI-H1975 CTRP1 1.9551 3.1839 1.9508 44.3602
EPLC-272H CTRP2; CTRP1 1.9902 3.3604 1.9811 21.9132
KNS-62 CTRP2; CTRP1 2.0108 3.5552 1.9926 20.3481
NCI-H1876 CTRP1 2.0367 3.0498 2.0354 43.1825
HCC1359 CTRP1 2.0415 3.0933 2.0398 43.1164
NCI-H838 CTRP2 2.0535 2.9163 2.0531 19.9271
EBC-1 CTRP2; CTRP1 2.1054 3.1627 2.1034 19.6642
NCI-H1944 CTRP2; CTRP1 2.1204 3.403 2.1128 19.5832
HCC4006 CTRP2; CTRP1 2.1275 2.8882 2.1274 19.5107
NCI-H2122 CTRP2; CTRP1 2.1285 3.1612 2.1267 20.901
T3M-10 CTRP2; CTRP1 2.1355 3.6298 2.1173 19.5183
NCI-H1437 CTRP1 2.192 3.0821 2.1913 40.9576
HCC78 CTRP2; CTRP1 2.2066 3.0544 2.2061 25.8742
NCI-H1666 CTRP2; CTRP1 2.2094 3.9227 2.17 20.46
NCI-H841 CTRP2; CTRP1 2.2235 3.1524 2.2225 18.8749
EKVX CTRP2 2.2698 4.2434 2.1915 18.751
COR-L279 CTRP1 2.3216 2.9996 2.3215 39.102
NCI-H1755 CTRP2; CTRP1 2.3874 3.2038 2.3869 17.7822
DMS 454 CTRP2 2.4005 4.8649 2.206 18.2901
NCI-H1299 CTRP2; CTRP1 2.404 4.355 2.3189 19.2411
NCI-H2286 CTRP2; CTRP1 2.4195 3.932 2.3904 18.9242
HCC33 CTRP1 2.4631 3.0383 2.4631 37.0801
Calu-6 CTRP2; CTRP1 2.4748 4.1016 2.4309 17.3473
RERF-LC-KJ CTRP1 2.4786 3.2621 2.4781 36.8627
LOU-NH91 CTRP2 2.519 3.7846 2.5048 23.0018
PC-14 CTRP2 2.5208 3.6468 2.5134 16.8376
NCI-H1693 CTRP2 2.5405 5.2834 2.2429 17.7312
NCI-H1355 CTRP2; CTRP1 2.558 3.7295 2.5483 17.867
HCC827 CTRP2; CTRP1 2.5605 3.9147 2.5395 17.8898
NCI-H1838 CTRP2 2.5679 4.2914 2.5039 16.7162
LCLC-103H CTRP2; CTRP1 2.5828 3.8161 2.5693 22.5213
SK-LU-1 CTRP2; CTRP1 2.591 3.4592 2.5894 16.4308
Sq-1 CTRP2; CTRP1 2.643 3.3221 2.6427 16.0803
NCI-H889 CTRP2 2.657 3.3299 2.6568 21.6845
NCI-H2085 CTRP2 2.7075 3.9745 2.6878 21.3152
NCI-H3255 CTRP1 2.7695 4.1513 2.7373 32.9338
LXF 289 CTRP2; CTRP1 2.7791 3.5888 2.7776 15.1784
NCI-H2073 CTRP1 2.7972 4.5902 2.701 32.9821
NCI-H650 CTRP2; CTRP1 2.8063 4.6628 2.6963 20.9467
NCI-H2081 CTRP2; CTRP1 2.8909 6.1046 2.3432 16.4202
COR-L105 CTRP2 2.8914 5.7246 2.4793 15.8251
CAL-12T CTRP2; CTRP1 2.9513 5.4802 2.6313 15.1662
NCI-H1184 CTRP2 3.0257 4.7584 2.9123 13.8403
NCI-H2030 CTRP2; CTRP1 3.0508 3.9885 3.0432 14.3454
NCI-H2170 CTRP2 3.1601 4.6216 3.0861 12.8068
NCI-H196 CTRP2 3.26 4.9745 3.1157 12.3906
HCC2935 CTRP2; CTRP1 3.2631 4.7679 3.1702 12.272
NCI-H441 CTRP2; CTRP1 3.2847 4.8629 3.1725 13.0659
HCC2108 CTRP2; CTRP1 3.306 4.0913 3.3007 11.6843
NCI-H1869 CTRP2 3.3217 5.2831 3.0942 12.2829
NCI-H661 CTRP2; CTRP1 3.3397 4.7306 3.261 15.962
COLO 699 CTRP2; CTRP1 3.3597 4.497 3.3222 11.4365
BEN CTRP2; CTRP1 3.3755 5.6316 3.0387 16.9201
NCI-H2405 CTRP2; CTRP1 3.3787 5.571 3.0637 16.7806
NCI-H1435 CTRP2; CTRP1 3.3921 4.6984 3.3241 11.3262
NCI-H1793 CTRP2; CTRP1 3.484 4.9191 3.3762 10.8555
SW1573 CTRP2 3.4885 5.0828 3.3358 14.8615
NCI-H1651 CTRP2 3.493 7.1934 2.5068 14.091
Lu-65 CTRP2; CTRP1 3.5215 4.1597 3.5186 10.2422
A-549 CTRP2; CTRP1 3.5338 5.2239 3.3467 10.8108
NCI-H1373 CTRP2; CTRP1 3.5481 4.5056 3.5218 10.8675
NCI-H2110 CTRP2; CTRP1 3.6472 6.0922 3.1506 11.2312
HOP-92 CTRP2 3.6798 6.8271 2.8608 12.2034
Calu-3 CTRP2; CTRP1 3.7165 6.1175 3.2129 10.8019
HOP-62 CTRP2 3.74 8.3392 2.2146 14.6571
NCI-H2126 CTRP2; CTRP1 3.7697 4.912 3.6892 8.8588
HCC95 CTRP2 3.8089 7.0215 2.9023 15.9501
NCI-H2291 CTRP2 3.846 8.0125 1.9202 10.2302
HCC1195 CTRP2; CTRP1 3.8595 5.0977 3.7392 8.4043
NCI-H322 CTRP2 3.873 6.6265 3.1466 10.5693
NCI-H1792 CTRP2; CTRP1 3.8961 5.0352 3.7963 8.6639
NCI-H1930 CTRP1 4.0513 7.2937 3.0208 22.6532
NCI-H2141 CTRP2; CTRP1 4.0595 5.571 3.7955 7.6139
COR-L88 CTRP1 4.0693 7.5682 2.9074 23.4001
SW1271 CTRP2 4.1003 5.9444 3.6803 7.862
NCI-H226 CTRP2 4.1188 5.263 3.9672 6.708
NCI-H1395 CTRP2 4.2156 5.6858 3.9097 6.6558
RERF-LC-Ad2 CTRP2 4.2918 5.273 4.151 5.5199
NCI-H460 CTRP2; CTRP1 4.353 5.4767 4.1446 5.4619
NCI-H2228 CTRP2 4.4593 6.9964 3.5463 7.5256
NCI-H2172 CTRP2; CTRP1 4.5419 5.8504 4.1789 5.1746
NCI-H1650 CTRP2 4.603 7.4024 3.4799 7.4806
SBC-5 CTRP2 4.6062 5.1357 4.5385 3.1607
RERF-LC-MS CTRP2 4.6511 5.9483 4.2339 4.2506
IA-LM CTRP2 4.718 6.6276 3.9666 5.2024
NCI-H2444 CTRP2 5.012 6.343 4.3679 2.9067
LUDLU-1 CTRP2 5.1105 9.1094 3.0667 8.1834
HCC1171 CTRP2 5.2532 6.9396 4.2647 2.8957
NCI-H2342 CTRP2; CTRP1 5.5651 8.93 3.5273 5.5189
RERF-LC-Ad1 CTRP2 5.5959 6.6088 3.7593 0.1221
NCI-H2023 CTRP2; CTRP1 5.7023 8.4101 3.8845 3.8207
NCI-H1623 CTRP2 6.2323 10.1973 3.3781 5.0147
Calu-1 CTRP2 8.3478 16.5579 1.7528 8.4232
Hs 888.Lu CTRP2 4.1187 5.5419 3.8652 7.0937
⏷ Show the Full List of 159 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 1.6092 2.3635 1.6092 22.8858
Yamato-SS CTRP2 1.651 2.0985 1.651 22.6075
G-401 CTRP2; CTRP1 1.2407 2.2552 1.2404 25.4138
KYM-1 CTRP2 1.4113 1.9917 1.4113 24.2039
TE 617.T CTRP2 1.469 2.1046 1.469 23.8199
TE 441.T CTRP2 1.5332 2.4139 1.5331 23.3923
Rh41 CTRP2 1.5511 2.0628 1.5511 31.7282
Rh18 CTRP2 1.5806 2.1879 1.5806 24.7237
RKN CTRP2; CTRP1 1.5904 2.2174 1.5904 23.0854
A-204 CTRP2 1.6003 3.361 1.5788 23.0171
RD CTRP2 1.6066 3.6232 1.5643 23.0457
GCT CTRP2 1.622 2.9742 1.6173 22.8163
SK-LMS-1 CTRP2 1.641 3.9638 1.5597 22.9496
TTC-709 CTRP2 1.6422 2.1209 1.6422 22.6657
MES-SA CTRP2 1.7038 2.1609 1.7038 22.2553
SW982 CTRP2 1.7141 2.3123 1.7141 22.1867
Hs 729.T CTRP2 1.7358 2.8095 1.7347 22.0462
BT-16 CTRP2 1.8063 2.4905 1.8063 21.5729
Tm87-16 CTRP2 1.8778 3.0944 1.8742 21.1083
G-402 CTRP2 2.071 3.2778 2.0661 19.8257
HT-1080 CTRP2; CTRP1 2.0827 2.89 2.0824 19.8096
BT-12 CTRP2 2.602 2.8691 2.602 16.2719
SK-UT-1 CTRP2 3.8699 6.3772 3.2547 10.1466
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 1.6842 2.6735 1.6837 22.388
HEY A8 CTRP2; CTRP1 0.3546 1.2817 0.3546 31.3103
OVCAR-8 CTRP2; CTRP1 0.4775 1.4135 0.4775 32.6667
TOV-21G CTRP2 0.879 1.6464 0.879 27.7504
OVKATE CTRP1 1.4059 3.1807 1.3885 52.1293
COV434 CTRP2; CTRP1 1.4083 2.1146 1.4083 24.2972
OV-90 CTRP2; CTRP1 1.4981 2.3456 1.498 23.6997
SNU-119 CTRP2 1.5299 3.3164 1.5086 23.4857
OVTOKO CTRP2 1.5933 2.3983 1.5932 31.3452
OC 314 CTRP2 1.5988 2.0383 1.5988 22.9549
ONCO-DG-1 CTRP2 1.5991 3.2278 1.585 31.3561
OV56 CTRP2 1.6166 1.9751 1.6166 22.8362
A2780 CTRP2; CTRP1 1.7097 2.8752 1.7078 23.8872
JHOC-5 CTRP2; CTRP1 1.8571 2.3546 1.8571 21.3101
RMUG-S CTRP1 1.886 3.3714 1.8738 45.3811
COV644 CTRP2; CTRP1 2.0495 3.0103 2.0486 20.0324
JHOM-1 CTRP2; CTRP1 2.1223 3.226 2.1194 19.5549
DOV13 CTRP2 2.2845 4.5509 2.1514 18.8443
Caov-3 CTRP2; CTRP1 2.4968 3.2807 2.4962 17.0546
OAW42 CTRP2; CTRP1 2.5152 3.0469 2.5151 16.9304
OVCAR-4 CTRP2; CTRP1 2.5839 3.9468 2.5613 17.7285
TYK-nu CTRP2; CTRP1 2.6261 3.718 2.6187 16.2164
JHOS-4 CTRP1 2.6355 3.3888 2.6349 34.6215
OVK18 CTRP2; CTRP1 2.6492 3.5136 2.6475 16.0437
IGROV-1 CTRP2; CTRP1 2.6637 3.9895 2.6413 17.1589
MCAS CTRP2 2.7333 3.9722 2.7149 16.562
JHOS-2 CTRP2 2.889 6.1946 2.3019 16.5029
SNU-840 CTRP2; CTRP1 2.9745 3.953 2.9663 13.9007
ES2 CTRP2 3.0012 4.8342 2.8682 14.0728
TOV-112D CTRP2 3.1394 4.6739 3.0536 12.9862
RMG-I CTRP2; CTRP1 3.1812 4.8336 3.0666 12.8931
OV7 CTRP2; CTRP1 3.2622 4.7052 3.1821 12.2328
OVMANA CTRP1 3.3103 3.9075 3.3094 24.9841
SNU-8 CTRP2 3.4533 4.1162 3.4502 14.4652
EFO-27 CTRP2; CTRP1 3.6327 6.3141 3.0428 11.6904
OAW28 CTRP2 3.67 5.5711 3.3737 10.2273
OVISE CTRP2 3.6893 4.1759 3.6883 9.0311
EFO-21 CTRP2; CTRP1 3.8449 5.4912 3.5951 8.9804
SK-OV-3 CTRP2; CTRP1 3.9726 5.2289 3.8229 7.7607
COV318 CTRP1 4.0515 5.9181 3.6464 17.6148
OVCAR-5 CTRP2 4.2668 8.6188 2.574 11.9794
Kuramochi CTRP2 4.8827 9.2052 2.8278 13.0624
OVSAHO CTRP2 5.317 7.5426 4.0145 5.222
FU-OV-1 CTRP2 5.4081 7.345 4.1813 4.0674
COV362 CTRP1 5.5123 9.1793 3.3633 13.2339
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 2.0315 2.93 2.031 20.0742
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.7788 5.5216 3.5088 9.4069
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 0.2156 1.9986 0.2114 43.9466
NCI-H28 CTRP2; CTRP1 2.3239 3.3446 2.3213 24.8197
MPP 89 CTRP2 2.7118 5.1569 2.4671 16.3998
NCI-H2052 CTRP2; CTRP1 2.7789 4.493 2.6992 21.0515
NCI-H2452 CTRP2 3.1 5.3479 2.8324 13.9035
ACC-MESO-1 CTRP2 3.6206 4.9332 3.5195 13.4101
IST-Mes1 CTRP2 4.4013 5.0848 4.3311 4.5313
JL-1 CTRP2 4.9504 5.5187 4.725 1.5356
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP CTRP2 2.2992 4.1848 2.2319 18.5174
22Rv1 CTRP2 2.5999 4.5085 2.5016 16.6223
LNCaP clone FGC CTRP2 2.6097 4.403 2.531 16.4886
PaCa-3 CTRP2; CTRP1 3.3018 5.3941 3.0404 12.6241
DU145 CTRP2 4.6775 8.0652 3.2183 8.4139
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 1.0044 1.6317 1.0044 21.9382
A-253 CTRP2 3.5568 5.8578 3.144 11.4204
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-StC-K140 CTRP2 0.5251 2.1719 0.5215 30.1199
SNU-16 CTRP2 0.8699 1.5989 0.8699 27.8109
ECC10 CTRP2 1.3741 3.0733 1.3608 24.4964
HGC-27 CTRP2 1.3873 2.77 1.3835 24.3766
OCUM-1 CTRP2 1.4109 9.4524 -0.6185 32.6786
NCI-N87 CTRP2 1.4453 2.7254 1.4429 23.9856
SNU-1 CTRP2 1.4652 2.6771 1.4635 23.8508
SNU-719 CTRP2 1.4982 3.2133 1.4817 25.3707
AGS CTRP2; CTRP1 1.5715 2.3322 1.5714 24.8663
SNU-5 CTRP2 1.6135 2.1179 1.6135 22.8571
23132/87 CTRP2 1.6143 2.0993 1.6143 31.1538
SNU-601 CTRP2 1.6186 2.4276 1.6186 22.8232
Hs 746.T CTRP2 1.6189 2.0993 1.6189 22.8214
SNU-216 CTRP2 1.6251 3.9275 1.5478 23.0422
GSS CTRP2 1.6321 2.1942 1.6321 30.9921
HuG1-N CTRP2 1.7042 2.4598 1.7041 22.2532
ECC12 CTRP2 1.7138 2.1706 1.7138 30.2502
SNU-620 CTRP2 1.7492 2.254 1.7492 29.9289
NUGC-4 CTRP2; CTRP1 2.012 3.3979 2.002 20.3123
SNU-668 CTRP2 2.1006 3.5158 2.0442 14.3435
IM95 CTRP2 2.2377 3.7003 2.2183 18.7636
MKN74 CTRP2; CTRP1 2.3945 4.3287 2.313 18.0108
LMSU CTRP2 2.4244 4.4145 2.3292 17.7801
KE-39 CTRP2 2.9922 5.8385 2.5469 15.2815
MKN7 CTRP2; CTRP1 3.2802 5.6766 2.9198 13.1365
Fu97 CTRP2; CTRP1 3.3466 4.092 3.3423 15.5508
NUGC-3 CTRP2 3.5872 4.1167 3.5861 9.7119
GSU CTRP2 3.9313 4.3037 3.9308 10.1116
MKN1 CTRP2 3.9919 6.7029 3.2314 13.5335
KATO III CTRP2 4.2939 8.1667 2.8208 10.9002
SH-10-TC CTRP2; CTRP1 4.629 5.3515 4.4868 3.3854
MKN45 CTRP2 4.7989 5.3763 4.6465 3.0205
SNG-M CTRP2; CTRP1 2.5768 3.1665 2.5767 17.6983
SNU-685 CTRP2 3.5863 4.2946 3.5794 9.7372
SNU-1077 CTRP2 3.6228 5.0169 3.5003 13.4947
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-62 CTRP2 -0.3542 0.3878 -0.3542 49.0324
B-CPAP CTRP2 1.5308 2.0836 1.5308 31.9121
FTC-238 CTRP2 1.5344 1.9025 1.5344 23.384
BHT-101 CTRP2 1.5537 2.0292 1.5537 23.2555
8305C CTRP2 1.5738 2.0761 1.5738 31.5213
SW579 CTRP2 1.5986 2.0352 1.5986 22.9564
CGTH-W-1 CTRP2 1.6645 3.1512 1.6554 30.7395
TT CTRP2 1.7621 2.7641 1.7615 21.8692
ML-1 [Human leukemia] CTRP2 2.0963 3.4141 2.0875 19.6701
TT2609-C02 CTRP2 4.0069 5.5209 3.7538 7.8319
FTC-133 CTRP2 4.2143 5.4524 4.0016 6.3051
8505C CTRP2 5.8763 9.2517 3.5873 4.693
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-2 CTRP2; CTRP1 0.396 0.9619 0.396 31.0345
YD-10B CTRP2 0.999 1.8614 0.9987 21.9783
SCC-4 CTRP2 1.1138 2.365 1.1127 26.1899
PE/CA-PJ34 (clone C12) CTRP2 1.2133 2.1028 1.2132 25.5235
SNU-1214 CTRP2 1.2454 2.1265 1.2453 25.3097
SCC-25 CTRP2 1.3804 2.472 1.3798 26.1544
PE/CA-PJ49 CTRP2 1.387 2.1632 1.387 24.366
CAL-33 CTRP2 1.5247 2.9704 1.5185 23.4695
BHY CTRP2 1.5274 2.1076 1.5274 31.943
SNU-899 CTRP2 1.5498 2.5398 1.5465 18.0692
PE/CA-PJ15 CTRP2 1.6049 2.1885 1.6049 22.9145
BICR 6 CTRP2 1.6375 2.054 1.6375 22.6975
BICR 22 CTRP2 1.6574 2.2123 1.6574 22.5643
BICR 16 CTRP2 1.7201 3.2105 1.7101 22.1803
SNU-1076 CTRP2 1.7515 2.1644 1.7515 29.9073
SCC-9 CTRP2; CTRP1 2.162 3.2708 2.1587 19.2919
BICR 56 CTRP2 2.3475 5.0277 2.1058 18.8116
SNU-1066 CTRP2 2.4029 4.0315 2.3621 24.1791
YD-8 CTRP2 2.5292 4.3097 2.4595 16.9939
CAL-27 CTRP2 2.7848 4.4169 2.7171 15.2842
Detroit 562 CTRP2 2.8202 4.4234 2.7541 20.5082
FaDu CTRP2 2.8884 4.786 2.7567 14.8189
SNU-1041 CTRP2 3.2472 4.9112 3.1177 16.9362
BICR 31 CTRP2 3.5465 6.8995 2.6929 13.2136
SNU-46 CTRP2 3.9836 7.867 2.1105 9.0875
HSC-4 CTRP2 4.3929 6.691 3.6305 7.3329
BICR 18 CTRP2 4.5803 5.2247 4.4794 3.4568
PE/CA-PJ41 (clone D2) CTRP2 4.709 8.6677 2.9462 9.4856
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J-BV CTRP2 0.6392 1.7241 0.6391 40.0109
RT-4 CTRP2; CTRP1 1.258 2.5528 1.2561 25.304
JMSU-1 CTRP2 1.4725 2.0243 1.4725 32.4422
BFTC-905 CTRP2 1.5169 4.737 1.2741 33.1066
639V CTRP2 1.5284 1.9543 1.5284 31.934
VM-CUB-1 CTRP2 1.5398 2.351 1.5397 31.8311
253J CTRP2 1.6353 2.1023 1.6353 30.9634
CAL-29 CTRP2 1.6364 3.8475 1.5705 31.2523
UM-UC-1 CTRP2 1.6603 2.5584 1.6601 22.5459
T24 CTRP2 1.6846 2.7297 1.6838 22.386
TCCSUP CTRP2 1.6894 2.2083 1.6894 22.3512
HT-1197 CTRP2 1.7153 2.6903 1.7148 22.1807
647V CTRP2 1.8098 2.3728 1.8098 21.5494
SCaBER CTRP2 1.8199 2.5778 1.8198 21.4823
BC-3C CTRP2 1.8476 3.5479 1.8231 21.3797
KU-19-19 CTRP2 1.8836 3.0382 1.8811 28.7194
U-BLC1 CTRP2 1.922 5.0116 1.6457 21.7656
5637 CTRP2; CTRP1 2.346 3.0012 2.346 18.0562
UM-UC-3 CTRP2; CTRP1 2.5421 3.157 2.542 16.7511
KMBC-2 CTRP2; CTRP1 2.9146 4.524 2.8401 14.5258
RT-112 CTRP2 3.3483 4.2004 3.3386 12.141
J82 CTRP2 3.4553 6.038 2.9651 12.3888
HT-1376 CTRP2; CTRP1 3.7615 7.5932 2.5965 13.1434
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 3.8076 4.202 3.8073 8.2408

References

1 Emerging therapies targeting the ubiquitin proteasome system in cancer. J Clin Invest. 2014 Jan;124(1):6-12.
2 Ubiquitin C-Terminal Hydrolase L1 regulates autophagy by inhibiting autophagosome formation through its deubiquitinating enzyme activity. Biochem Biophys Res Commun. 2018 Mar 4;497(2):726-733.