Details of the Drug

General Information of Drug (ID: DMQX3W6)

Drug Name
I-CBP112
Synonyms
1640282-31-0; I-CBP 112; CHEMBL3774655; 1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one; 1-[7-(3,4-dimethoxyphenyl)-9-{[(3S)-1-methylpiperidin-3-yl]methoxy}-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one; GTPL8236; SCHEMBL17620385; MolPort-035-765-871; EX-A2474; ZINC96024493; BDBM50151663; AKOS024458402; CS-6146; NCGC00350526-04; HY-19541; I-CBP112, &gt
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 468.6
Logarithm of the Partition Coefficient (xlogp) 3.8
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C27H36N2O5
IUPAC Name
1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one
Canonical SMILES
CCC(=O)N1CCOC2=C(C1)C=C(C=C2OC[C@H]3CCCN(C3)C)C4=CC(=C(C=C4)OC)OC
InChI
InChI=1S/C27H36N2O5/c1-5-26(30)29-11-12-33-27-22(17-29)13-21(20-8-9-23(31-3)24(14-20)32-4)15-25(27)34-18-19-7-6-10-28(2)16-19/h8-9,13-15,19H,5-7,10-12,16-18H2,1-4H3/t19-/m0/s1
InChIKey
YKNAKDFZAWQEEO-IBGZPJMESA-N
Cross-matching ID
PubChem CID
90488984
TTD ID
D0J3JI

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CREB-binding protein (CREBBP) TTFRCTK CBP_HUMAN Inhibitor [2]
Histone acetyltransferase KAT6B (KAT6B) TTH4VJL KAT6B_HUMAN Inhibitor [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 6.2654 8.3008 2.6607 0.4729
EW-22 GDSC1 4.0966 6.5488 2.2995 5.6468
CHSA0108 GDSC1 4.167 7.8273 1.7288 9.7124
EW-11 GDSC1 4.336 11.2781 0.1541 19.3293
CHSA0011 GDSC1 4.3972 7.8903 1.8598 8.1036
MG-63 GDSC1 4.4106 13.797 -1.0383 24.6313
HuO9 GDSC1 4.4673 7.113 2.2747 4.9085
MHH-ES-1 GDSC1 4.4712 6.5459 2.537 3.0605
EW-3 GDSC1 4.5197 8.519 1.6411 9.3498
ES1 GDSC1 4.5986 7.0811 2.3696 3.95
H-EMC-SS GDSC1 4.6317 8.4792 1.7362 8.3754
CADO-ES1 GDSC1 4.6366 9.2039 1.3914 10.7792
NOS-1 [Human HNSCC] GDSC1 5.056 7.4835 2.4467 2.6092
CHSA8926 GDSC1 5.0565 7.056 2.6259 1.5762
TC-71 GDSC1 5.098 6.7081 2.7822 0.7776
CAL-72 GDSC1 5.1054 6.8044 2.7484 0.9178
SJSA-1 GDSC1 5.1251 7.1879 2.6048 1.6042
ES8 GDSC1 5.2077 7.1847 2.6446 1.3043
U2OS GDSC1 5.2439 8.1408 2.2629 3.4397
A-673 GDSC1 5.2668 6.7786 2.8249 0.4947
NY GDSC1 5.2783 7.7838 2.4334 2.355
HuO-3N1 GDSC1 5.3016 8.0367 2.3383 2.8817
EW-1 GDSC1 5.3499 7.2795 2.6706 1.0397
CAL-78 GDSC1 5.4297 7.2147 2.729 0.7313
SaOS-2 GDSC1 5.4336 7.3908 2.6638 0.9944
HOS GDSC1 5.5357 7.139 2.7988 0.4287
EW-13 GDSC1 5.6158 7.389 2.7394 0.5715
EW-18 GDSC1 5.76 8.4957 2.374 2.0508
G-292 clone A141B1 GDSC1 5.7891 8.1764 2.5141 1.3334
ES5 GDSC1 5.8265 8.6991 2.3228 2.2396
ES4 GDSC1 5.8408 8.032 2.5916 0.9589
EW-7 GDSC1 5.8586 7.5428 2.7768 0.3438
ES6 GDSC1 5.8632 7.66 2.737 0.447
SK-ES-1 GDSC1 6.0488 7.8724 2.7313 0.3811
SK-PN-DW GDSC1 6.2772 8.0133 2.7649 0.2318
EW-16 GDSC1 6.2979 8.4443 2.6219 0.5669
ES7 GDSC1 6.3012 8.6047 2.5651 0.7424
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 147 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 4.6095 6.4114 2.6723 1.9372
Kasumi-1 GDSC1 2.9975 6.0811 1.6634 14.2309
WSU-DLCL2 GDSC1 2.9983 4.3451 2.5208 7.5968
HH [Human lymphoma] GDSC1 3.2716 6.8721 1.5048 14.3549
OCI-AML-3 GDSC1 3.3074 4.7076 2.617 5.6123
NCI-H929 GDSC1 3.32 6.2594 1.8516 11.5603
P30/OHK GDSC1 3.336 7.5386 1.2253 16.1251
MOLT-13 GDSC1 3.3369 6.3015 1.8446 11.5526
A3/Kawakami GDSC1 3.4639 4.924 2.6359 4.918
SKM-1 GDSC1 3.5125 9.7381 0.2712 21.4641
DG-75 GDSC1 3.622 6.7865 1.8329 10.6441
L-540 GDSC1 3.6788 7.0195 1.7615 10.9961
MOLP-8 GDSC1 3.6865 6.4771 2.0369 8.8665
HAL-01 GDSC1 3.7127 6.0663 2.2602 7.0551
OCI-AML-2 GDSC1 3.7241 5.742 2.4285 5.7152
Daudi GDSC1 3.7606 5.47 2.5879 4.3801
Raji GDSC1 3.7671 6.8937 1.8921 9.7164
JVM-2 GDSC1 3.8269 8.5669 1.1075 15.2015
HT GDSC1 3.8374 8.0277 1.3836 13.2464
Mono-Mac-6 GDSC1 3.8469 7.1881 1.807 10.1062
Karpas-620 GDSC1 3.8901 8.9472 0.9677 15.9219
RL GDSC1 3.9262 5.7881 2.5488 4.2245
NB4 GDSC1 3.9513 6.3059 2.3164 5.9165
L-363 GDSC1 3.9561 6.1708 2.3852 5.3802
MOLT-16 GDSC1 4.0086 8.6683 1.1972 13.9914
DEL GDSC1 4.0186 8.3793 1.3478 12.9132
KMS-11 GDSC1 4.0921 9.3669 0.9148 15.6035
CRO-AP2 GDSC1 4.104 5.9217 2.6016 3.3943
MLMA GDSC1 4.1724 7.8445 1.7242 9.7298
Loucy GDSC1 4.1777 6.7196 2.2725 5.6352
P32/ISH GDSC1 4.214 5.9406 2.6602 2.7369
CA46 GDSC1 4.2334 7.3044 2.0296 7.2965
HC-1 GDSC1 4.2395 6.866 2.2439 5.6884
OCI-M1 GDSC1 4.2881 8.1029 1.6809 9.7103
MV4-11 GDSC1 4.2986 8.1458 1.6675 9.7771
MHH-PREB-1 GDSC1 4.3307 7.9714 1.7748 8.9066
Karpas-299 GDSC1 4.3344 9.1174 1.2186 12.8324
JVM-3 GDSC1 4.3491 7.4457 2.0405 6.907
MN-60 GDSC1 4.3511 6.5925 2.444 3.9625
H9 GDSC1 4.352 7.8151 1.865 8.1881
CESS GDSC1 4.3759 6.7548 2.3842 4.3337
SU-DHL-8 GDSC1 4.3807 6.0228 2.7184 2.0286
BC-1 GDSC1 4.3891 7.1593 2.203 5.6133
MOLM-13 GDSC1 4.399 7.2893 2.1481 5.9899
Jurkat GDSC1 4.4072 6.2886 2.6157 2.6546
HL-60 GDSC1 4.4112 6.4603 2.5407 3.1559
Karpas-422 GDSC1 4.422 7.1531 2.2272 5.358
BV-173 GDSC1 4.4327 6.8719 2.3651 4.341
BL-41 GDSC1 4.4423 14.5053 -1.3657 25.7809
RPMI-8402 GDSC1 4.4493 8.2207 1.7365 8.8577
HEL GDSC1 4.489 5.9605 2.8015 1.3505
NALM-6 GDSC1 4.519 8.3329 1.7303 8.7144
SU-DHL-10 GDSC1 4.5376 5.6135 2.9625 0.491
JJN-3 GDSC1 4.5435 6.2053 2.726 1.7146
CMK GDSC1 4.5568 9.6419 1.1226 12.8217
P31/FUJ GDSC1 4.5698 5.7173 2.9365 0.5725
MOLM-16 GDSC1 4.5717 6.7958 2.4828 3.2299
GDM-1 GDSC1 4.5749 8.3319 1.7685 8.2925
Jiyoye GDSC1 4.6134 6.9892 2.42 3.5733
NOMO-1 GDSC1 4.6186 17.9947 -2.9638 30.1181
ALL-SIL GDSC1 4.6395 6.4549 2.6694 1.9084
MC116 GDSC1 4.6695 5.5683 3.0309 0.1863
NKM-1 GDSC1 4.6726 8.8035 1.6087 9.1704
697 GDSC1 4.683 6.3871 2.72 1.5463
RPMI-8226 GDSC1 4.693 7.6952 2.1449 5.3167
SR GDSC1 4.7096 13.1174 -0.4729 21.3168
KG-1 GDSC1 4.7429 6.8444 2.5565 2.4386
THP-1 GDSC1 4.7517 6.7853 2.5866 2.2369
RCH-ACV GDSC1 4.7657 6.9155 2.5378 2.5174
P12-Ichikawa GDSC1 4.8274 6.0631 2.9131 0.4676
TK [Human B-cell lymphoma] GDSC1 4.8453 6.771 2.6406 1.7742
L-428 GDSC1 4.8486 7.7544 2.2117 4.5173
RPMI-6666 GDSC1 4.8669 6.6121 2.7165 1.3268
Sc-1 GDSC1 4.9011 6.5961 2.739 1.171
SU-DHL-5 GDSC1 4.9062 6.0107 2.9628 0.2633
Karpas-231 GDSC1 4.9429 6.2171 2.9025 0.4299
ME1 GDSC1 4.9706 6.3096 2.8795 0.4928
MHH-CALL-2 GDSC1 4.9735 6.5499 2.7896 0.8552
ATN-1 GDSC1 4.9766 6.667 2.7452 1.0587
MOLT-4 GDSC1 4.9802 6.7967 2.695 1.3045
CCRF-CEM GDSC1 4.9843 7.4183 2.437 2.7851
MEG-01 GDSC1 5.0201 7.2504 2.5273 2.1814
Farage GDSC1 5.0417 6.64 2.7843 0.8171
OCI-AML-5 GDSC1 5.0449 6.0808 2.9891 0.1505
U266B1 GDSC1 5.1009 6.9739 2.6798 1.2459
ARH-77 GDSC1 5.1082 7.0646 2.6468 1.4044
AMO1 GDSC1 5.1169 7.0034 2.6753 1.2508
KOPN-8 GDSC1 5.1394 6.703 2.8015 0.6661
SU-DHL-4 GDSC1 5.144 6.7264 2.7946 0.6899
GA-10 GDSC1 5.1749 6.6989 2.8176 0.5797
OPM-2 GDSC1 5.181 6.868 2.7564 0.8166
EJM GDSC1 5.1903 6.6559 2.8396 0.4917
QIMR-WIL GDSC1 5.2005 8.5799 2.0443 4.9364
Ramos.2G6.4C10 GDSC1 5.2078 6.9599 2.7326 0.8951
SUP-M2 GDSC1 5.2262 6.5239 2.9009 0.288
Ku812 GDSC1 5.2431 7.306 2.6124 1.4259
OCI-Ly19 GDSC1 5.245 8.0577 2.2995 3.2094
WSU-NHL GDSC1 5.2504 6.8904 2.7769 0.6788
RPMI-8866 GDSC1 5.2524 6.9464 2.7566 0.7574
Reh GDSC1 5.2823 6.7005 2.8592 0.3781
PL-21 GDSC1 5.3103 8.1825 2.2803 3.2212
ROS-50 GDSC1 5.3243 7.2871 2.6564 1.128
L-1236 GDSC1 5.3252 7.8671 2.422 2.3538
JeKo-1 GDSC1 5.3574 6.8369 2.839 0.3999
GR-ST GDSC1 5.3603 9.1056 1.9003 5.5716
KE-37 GDSC1 5.3617 6.6941 2.8912 0.2578
SU-DHL-16 GDSC1 5.3759 6.6149 2.9237 0.1822
KCL-22 GDSC1 5.3772 9.0014 1.957 5.1661
DND-41 GDSC1 5.3927 7.2271 2.709 0.8389
IM-9 GDSC1 5.4347 6.6253 2.9409 0.1359
Karpas-1106P GDSC1 5.4444 7.1695 2.7518 0.6363
RS4;11 GDSC1 5.4449 7.315 2.6976 0.8437
JURL-MK1 GDSC1 5.4534 7.373 2.6791 0.9128
EM-2 GDSC1 5.4781 6.9664 2.8385 0.3439
K-562 GDSC1 5.5011 7.2937 2.7287 0.682
Hs 445 GDSC1 5.5133 7.7681 2.5517 1.4323
SU-DHL-6 GDSC1 5.5242 7.2489 2.7544 0.5761
DB GDSC1 5.5353 7.4636 2.679 0.8473
CML-T1 GDSC1 5.5428 7.0606 2.8294 0.34
TUR GDSC1 5.5531 6.948 2.8725 0.2328
Namalwa GDSC1 5.555 7.2954 2.7496 0.5737
ML-2 GDSC1 5.5636 7.2279 2.7775 0.4786
BALL-1 GDSC1 5.6413 7.2978 2.7822 0.4249
EB2 GDSC1 5.6596 7.3658 2.7648 0.4669
U-698-M GDSC1 5.675 7.4417 2.7433 0.5246
NU-DUL-1 GDSC1 5.6877 7.4117 2.7591 0.4694
ALL-PO GDSC1 5.688 8.0667 2.5123 1.4409
KMOE-2 GDSC1 5.6905 8.1393 2.4848 1.5702
YT GDSC1 5.7831 7.0275 2.9257 0.0912
CTB-1 GDSC1 5.7849 8.0088 2.5769 1.0636
A4/Fukuda GDSC1 5.787 7.4126 2.796 0.3246
VL51 GDSC1 5.793 7.6126 2.7272 0.5108
SUP-B8 GDSC1 5.7965 7.4012 2.8035 0.3031
LP-1 GDSC1 5.8236 7.5112 2.7749 0.3626
KY821 GDSC1 5.8319 7.5055 2.78 0.3464
KM-H2 GDSC1 5.832 7.6856 2.7159 0.5247
Karpas-45 GDSC1 5.8573 7.5434 2.776 0.3461
LAMA-84 GDSC1 5.9124 7.7884 2.7098 0.5016
CTV-1 GDSC1 5.9291 7.7415 2.7329 0.4281
PF-382 GDSC1 5.944 7.4561 2.8373 0.1884
LC4-1 GDSC1 5.9446 7.9704 2.6564 0.6513
EHEB GDSC1 5.9553 7.6775 2.7652 0.3346
HDLM-2 GDSC1 5.9648 7.966 2.666 0.6086
SUP-HD1 GDSC1 6.0234 8.004 2.6749 0.5491
SUP-T1 GDSC1 6.0505 7.7338 2.7801 0.2681
RC-K8 GDSC1 6.1309 7.8098 2.7827 0.2388
ST486 GDSC1 6.139 7.7665 2.8003 0.2041
⏷ Show the Full List of 147 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYAE-1 GDSC1 4.9954 7.4518 2.4284 2.8201
SK-GT-4 GDSC1 5.0084 7.5805 2.3796 3.1056
KYSE-50 GDSC1 5.4218 7.3357 2.68 0.9356
KYSE-220 GDSC1 5.5508 7.9473 2.4974 1.6599
ESO-51 GDSC1 5.6581 7.5218 2.7074 0.6542
ESO-26 GDSC1 5.7639 7.6178 2.7141 0.5681
OACP4 C GDSC1 5.8259 9.0258 2.1875 2.9868
HCE-4 GDSC1 5.9192 7.9566 2.6514 0.6835
TE-12 GDSC1 6.0329 9.1618 2.2325 2.4629
OACM5.1 C GDSC1 6.2643 8.8254 2.4682 1.1216
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 5.3603 7.8296 2.4549 2.1198
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-DZ GDSC1 3.3778 4.6508 2.7035 4.6791
IMR-5 GDSC1 3.9949 7.3081 1.8581 9.2647
SK-N-SH GDSC1 4.0173 6.7118 2.1657 6.8745
GI-ME-N GDSC1 4.0938 7.3217 1.9232 8.4839
Kelly GDSC1 4.1836 19.1832 -3.9026 33.3319
GOTO GDSC1 4.2993 7.5804 1.9419 7.7666
SJNB-13 GDSC1 4.3787 8.0892 1.7512 8.9448
TGW GDSC1 4.4222 7.0577 2.2721 5.0327
NB1 GDSC1 4.5084 6.4813 2.5871 2.6538
SJNB-7 GDSC1 4.797 13.4616 -0.5772 21.5358
SK-N-MC-IXC GDSC1 5.1098 6.2707 2.9468 0.2203
SK-N-BE(2)-M17 GDSC1 5.1294 6.9013 2.7212 1.0183
NH-12 GDSC1 5.2216 7.0179 2.7162 0.9546
SJNB-10 GDSC1 5.4415 7.4388 2.6487 1.0532
SJNB-6 GDSC1 5.582 7.5229 2.6761 0.8232
CHP-126 GDSC1 5.6126 7.4628 2.711 0.6712
SiMa GDSC1 5.6464 7.832 2.5855 1.1467
NB(TU)1 GDSC1 5.7612 7.5706 2.7301 0.519
LA-N-6 GDSC1 5.7735 7.4914 2.7632 0.4158
SK-N-FI GDSC1 5.7939 7.3778 2.8107 0.2874
SJNB-5 GDSC1 5.9317 8.273 2.5383 1.1028
KP-N-YN GDSC1 6.0834 8.068 2.6749 0.5186
SJNB-12 GDSC1 6.3456 8.2564 2.7058 0.3309
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 4.32 6.5322 2.4527 3.9701
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-330 GDSC1 0.013 14.935 -5.4295 47.5289
HCC1428 GDSC1 4.1223 6.2828 2.4436 4.5064
CAMA-1 GDSC1 4.3049 7.8146 1.8327 8.5549
BT-474 GDSC1 4.4381 9.0788 1.3124 11.8844
HCC2157 GDSC1 4.458 6.181 2.6913 2.0677
HCC2218 GDSC1 4.4815 8.2775 1.7312 8.8082
JIMT-1 GDSC1 4.5949 9.8767 1.0353 13.2851
MDA-MB-415 GDSC1 4.9037 7.099 2.5318 2.3313
DU4475 GDSC1 4.9106 6.3393 2.8436 0.6771
HCC202 GDSC1 4.944 7.0044 2.5923 1.9129
HCC1500 GDSC1 4.9481 7.2665 2.4832 2.5575
BT-483 GDSC1 4.9587 9.6539 1.3941 9.9058
MDA-MB-231 GDSC1 4.9617 7.878 2.2218 4.2221
COLO 824 GDSC1 4.9659 7.7064 2.3007 3.6908
HCC1419 GDSC1 4.9802 6.6523 2.7526 1.0196
OCUB-M GDSC1 5.0678 7.1581 2.5895 1.7603
CAL-120 GDSC1 5.1014 6.6798 2.7945 0.7241
HCC1569 GDSC1 5.1226 7.8626 2.3184 3.2969
MDA-MB-361 GDSC1 5.1622 7.554 2.4714 2.3015
MDA-MB-453 GDSC1 5.2097 7.6027 2.4748 2.2136
MCF-7 GDSC1 5.2664 7.7245 2.4522 2.2634
EFM-192A GDSC1 5.3294 6.8608 2.8195 0.4757
EFM-19 GDSC1 5.3382 7.7084 2.4941 1.933
Hs 578T GDSC1 5.369 7.4876 2.5976 1.3619
HDQ-P1 GDSC1 5.3944 7.0864 2.7625 0.6312
MDA-MB-175-VII GDSC1 5.4544 7.1748 2.7539 0.6224
CAL-85-1 GDSC1 5.4748 7.8503 2.5012 1.7282
MDA-MB-436 GDSC1 5.529 7.3478 2.7199 0.6952
MDA-MB-468 GDSC1 5.5408 7.1244 2.806 0.4053
Evsa-T GDSC1 5.5852 7.2354 2.7831 0.4501
MRK-nu-1 GDSC1 5.6009 6.8759 2.914 0.1415
HCC70 GDSC1 5.6149 7.3351 2.7586 0.5095
MDA-MB-157 GDSC1 5.6237 7.7403 2.611 1.056
BT-20 GDSC1 5.7588 7.4289 2.7798 0.3774
HCC1806 GDSC1 5.8491 7.5077 2.7855 0.3261
HCC38 GDSC1 5.8609 7.6604 2.736 0.451
MFM-223 GDSC1 5.9096 7.7296 2.7298 0.4457
HCC1187 GDSC1 5.9369 7.607 2.783 0.2998
HCC1937 GDSC1 5.9574 7.7921 2.7256 0.4352
HCC1954 GDSC1 5.9604 7.9841 2.6576 0.6382
HCC1395 GDSC1 6.0221 7.8265 2.7375 0.3762
BT-549 GDSC1 6.084 7.8232 2.7613 0.2974
T-47D GDSC1 6.2187 8.3246 2.6345 0.5694
CAL-51 GDSC1 6.2239 7.9229 2.777 0.224
HCC1143 GDSC1 6.2515 8.6471 2.5297 0.8971
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC1 4.2384 7.6702 1.8561 8.569
U-87MG ATCC GDSC1 4.2484 6.314 2.5095 3.7261
KNS-42 GDSC1 4.349 7.5933 1.9697 7.4274
LN-405 GDSC1 4.4067 6.2526 2.6314 2.5508
42-MG-BA GDSC1 4.4419 6.8286 2.3907 4.1385
YH-13 GDSC1 4.4879 7.1101 2.2889 4.7591
LN-18 GDSC1 4.5139 5.4498 3.0139 0.3147
NMC-G1 GDSC1 4.5686 6.4236 2.6454 2.1708
D-263MG GDSC1 4.6 6.2382 2.7408 1.5435
SF268 GDSC1 4.6698 6.8679 2.5062 2.8886
GI-1 GDSC1 4.8315 6.9 2.5791 2.157
CAS-1 GDSC1 4.8653 6.4267 2.79 0.9587
DK-MG GDSC1 4.9509 6.4728 2.8096 0.7874
SF126 GDSC1 4.9802 7.0198 2.6038 1.7972
ONS-76 GDSC1 5.1083 6.964 2.6871 1.2021
D283 Med GDSC1 5.1513 6.6494 2.8264 0.5634
D-542MG GDSC1 5.1635 6.9954 2.6995 1.0859
Becker GDSC1 5.1712 12.6129 0.1129 17.0956
D-502MG GDSC1 5.1969 7.7326 2.4136 2.5907
SF295 GDSC1 5.2296 6.8274 2.7919 0.6369
A-172 GDSC1 5.2506 10.3004 1.2793 9.9375
LNZTA3WT4 GDSC1 5.2676 6.7737 2.827 0.4873
U-251MG GDSC1 5.3067 6.6847 2.8741 0.3241
KNS-81-FD GDSC1 5.3085 7.2742 2.6545 1.1523
SK-MG-1 GDSC1 5.3087 7.5241 2.5551 1.6441
YKG-1 GDSC1 5.318 6.6262 2.8989 0.256
Daoy GDSC1 5.3418 7.1405 2.7205 0.8329
Hs 683 GDSC1 5.3869 6.7785 2.8709 0.2981
SF539 GDSC1 5.5178 7.1775 2.778 0.5024
D-392MG GDSC1 5.5349 7.6346 2.6135 1.1239
8-MG-BA GDSC1 5.5785 7.1197 2.8218 0.3444
AM-38 GDSC1 5.6142 7.56 2.6754 0.8019
GB-1 GDSC1 5.7127 7.266 2.82 0.2953
GaMG GDSC1 5.7317 7.2842 2.8206 0.2869
U-118MG GDSC1 5.7821 7.5785 2.7353 0.4922
T98G GDSC1 5.8488 7.3785 2.8302 0.2278
MOG-G-UVW GDSC1 5.9935 7.9934 2.6672 0.5888
LN-229 GDSC1 6.075 7.5493 2.8513 0.1374
SNB-75 GDSC1 6.0866 8.3895 2.5586 0.9046
D-336MG GDSC1 6.1701 8.5609 2.5287 0.9574
KS-1 [Human Krukenberg tumour] GDSC1 6.1871 8.6113 2.5168 0.9903
SW1088 GDSC1 6.2307 8.4259 2.6026 0.6613
KINGS-1 GDSC1 6.2319 8.2347 2.6716 0.4585
KALS-1 GDSC1 6.2783 8.6677 2.5329 0.8679
Onda 10 GDSC1 6.2896 7.9245 2.7993 0.1708
MOG-G-CCM GDSC1 6.2983 8.337 2.6602 0.4597
Onda 11 GDSC1 6.403 8.2196 2.739 0.2458
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 5.0087 6.648 2.7669 0.9248
ETK-1 GDSC1 5.1804 8.0179 2.2821 3.4274
TGBC24TKB GDSC1 5.9477 7.8037 2.7178 0.4613
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EN GDSC1 -0.3971 181.8075 -89.0386 49.9153
KLE GDSC1 4.3679 7.236 2.1529 6.0323
MFE-296 GDSC1 5.2654 7.9758 2.3455 2.8949
AN3-CA GDSC1 5.645 7.6062 2.6707 0.7974
MFE-319 GDSC1 5.6496 7.1094 2.8515 0.2462
RL95-2 GDSC1 5.8793 7.5799 2.7714 0.3489
MFE-280 GDSC1 6.1309 8.4988 2.5359 0.9585
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 GDSC1 3.7003 5.9084 2.3289 6.5605
KTCTL-195 GDSC1 4.1904 6.7712 2.2564 5.7225
BB65-RCC GDSC1 4.4278 6.6509 2.4639 3.6544
Caki-1 GDSC1 4.4405 7.704 1.9784 7.1241
786-O GDSC1 4.5482 7.0897 2.3354 4.2954
LB2241-RCC GDSC1 4.5569 6.9498 2.4046 3.7947
KTCTL-13 GDSC1 4.6743 8.2305 1.8824 7.2251
CAL-54 GDSC1 4.6845 6.6011 2.6303 2.0754
A-498 GDSC1 4.776 6.4019 2.7589 1.2133
KTCTL-1M GDSC1 4.9168 7.8365 2.2145 4.3603
SW13 GDSC1 4.9963 7.4235 2.4412 2.7394
KMRC-1 GDSC1 5.0905 6.466 2.8697 0.4509
TK-10 GDSC1 5.0923 7.7623 2.3457 3.1761
BFTC-909 GDSC1 5.1464 6.7512 2.7862 0.7216
769-P GDSC1 5.3269 7.3581 2.6298 1.2503
LB996-RCC GDSC1 5.3714 7.9622 2.4052 2.3848
SW156 GDSC1 5.4374 7.5362 2.609 1.2372
OS-RC-2 GDSC1 5.4581 7.1859 2.7513 0.6292
NCC021 GDSC1 5.4624 8.3732 2.2782 2.994
LB1047-RCC GDSC1 5.4935 8.5899 2.2017 3.4058
KTCTL-21 GDSC1 5.5413 8.0767 2.4408 1.9649
HA7-RCC GDSC1 5.6817 7.9998 2.5358 1.3376
SN12C GDSC1 5.8086 7.5054 2.7714 0.3782
NCC010 GDSC1 5.836 8.7227 2.3178 2.2547
KMRC-20 GDSC1 5.8381 7.6189 2.7421 0.4445
KTCTL-26A GDSC1 5.8505 7.579 2.761 0.3874
A-704 GDSC1 5.9628 7.839 2.7109 0.4736
ACHN GDSC1 5.9771 7.5221 2.8265 0.1991
VMRC-RCZ GDSC1 6.0075 7.6083 2.8079 0.2254
KTCTL-140 GDSC1 6.3022 8.4103 2.6357 0.5251
RXF 393L GDSC1 6.665 8.9928 2.5653 0.5523
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-407 GDSC1 -2.312 67.0987 -33.3751 51.291
HT-29 GDSC1 3.9126 5.9503 2.4614 4.9211
RKO GDSC1 3.9521 6.0205 2.4548 4.864
HCC2998 GDSC1 4.4731 7.7776 1.965 7.1373
SK-CO-1 GDSC1 4.5648 6.5575 2.5849 2.5655
KM12 GDSC1 4.7491 6.5742 2.6748 1.713
SNU-1040 GDSC1 4.7923 7.1285 2.4593 2.9731
LS411N GDSC1 4.8231 6.8552 2.5939 2.0812
RCM-1 [Human ESC] GDSC1 5.0365 6.5973 2.7985 0.761
NCI-H716 GDSC1 5.054 7.482 2.4463 2.6149
SNU-81 GDSC1 5.0657 7.0122 2.6481 1.4478
SNU-C5 GDSC1 5.1212 7.8735 2.3129 3.3341
COLO205 GDSC1 5.1245 6.8168 2.7518 0.8851
SNU-C1 GDSC1 5.1547 7.9692 2.2894 3.4258
DiFi GDSC1 5.1897 7.819 2.373 2.8471
SW1417 GDSC1 5.2578 7.1135 2.6949 1.0163
LS1034 GDSC1 5.2622 6.7947 2.8172 0.5238
SW1116 GDSC1 5.4226 7.4409 2.6397 1.1107
SNU-61 GDSC1 5.4269 7.6518 2.5586 1.4912
LS123 GDSC1 5.5177 7.2318 2.7582 0.5674
SW837 GDSC1 5.5611 7.625 2.6285 1.0352
LS180 GDSC1 5.5836 6.904 2.8984 0.1723
LS513 GDSC1 5.7289 7.2842 2.8196 0.2903
SW1463 GDSC1 5.7837 7.6106 2.7244 0.5247
COLO 678 GDSC1 5.7841 7.5938 2.7306 0.5054
NCI-H508 GDSC1 5.8508 19.5757 -2.8058 26.6293
CL-11 GDSC1 5.9284 8.5565 2.427 1.6005
SW626 GDSC1 5.9564 8.6414 2.4061 1.6713
SW620 GDSC1 5.9891 7.8173 2.7285 0.4132
T84 GDSC1 5.9948 8.3362 2.5408 1.0419
NCI-H747 GDSC1 6.108 8.6921 2.4529 1.3136
CCK-81 GDSC1 6.1359 8.0886 2.6874 0.4586
COLO 320HSR GDSC1 6.2464 8.0259 2.7497 0.27
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 4.8129 7.0071 2.5234 2.5291
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-1 GDSC1 4.0451 6.0104 2.5221 4.1188
JHH-6 GDSC1 4.3231 5.3958 2.9531 0.7387
JHH-7 GDSC1 4.7849 6.7166 2.633 1.9056
Hep-G2/C3A GDSC1 5.1904 6.7425 2.8077 0.6056
Hep 3B2.1-7 GDSC1 5.2642 6.8128 2.8114 0.5428
SNU-423 GDSC1 5.4758 8.1089 2.3958 2.2942
JHH-4 GDSC1 5.5063 7.7601 2.5517 1.4398
JHH-1 GDSC1 5.5256 12.4132 0.4558 14.2762
SNU-449 GDSC1 5.5438 9.2908 1.9226 5.071
SK-HEP-1 GDSC1 5.6897 7.2418 2.82 0.3039
HLE GDSC1 5.7018 7.6034 2.6948 0.6704
Huh-7 GDSC1 5.7225 7.2625 2.8248 0.2805
SNU-398 GDSC1 5.8172 7.6597 2.7196 0.5214
JHH-2 GDSC1 5.8638 7.2546 2.8775 0.1414
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 165 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H196 GDSC1 -6.8326 2.5134 -7.5501 79.5977
NCI-H2291 GDSC1 1.9308 26.2689 -9.3305 44.2009
NCI-H727 GDSC1 3.5314 9.7537 0.2789 21.3533
BEN GDSC1 3.6877 5.7892 2.3783 6.2156
NCI-H1688 GDSC1 4.0687 6.1425 2.475 4.4088
NCI-H1944 GDSC1 4.1151 6.573 2.3005 5.5903
NCI-H1304 GDSC1 4.1279 7.2039 2.0047 7.7747
HARA [Human squamous cell lung carcinoma] GDSC1 4.1376 7.1708 2.0276 7.5759
NCI-H226 GDSC1 4.1899 6.2314 2.5112 3.8482
Calu-3 GDSC1 4.2592 6.5875 2.3886 4.5755
HCC78 GDSC1 4.2605 7.8017 1.8079 8.8614
RERF-LC-KJ GDSC1 4.274 7.6217 1.9045 8.1115
NCI-H1650 GDSC1 4.3451 6.5295 2.4694 3.7952
NCI-H2030 GDSC1 4.3678 6.2241 2.6219 2.6889
NCI-H1793 GDSC1 4.3873 7.3009 2.1348 6.1162
Lu-139 GDSC1 4.3925 7.5139 2.037 6.8194
COR-L23 GDSC1 4.3955 6.0567 2.7116 2.046
NCI-H2122 GDSC1 4.4071 8.0811 1.7748 8.6957
NCI-H2461 GDSC1 4.4648 10.2744 0.7461 15.5073
NCI-H345 GDSC1 4.4811 5.28 3.0625 0.1836
SHP-77 GDSC1 4.4893 6.95 2.3638 4.2241
NCI-H847 GDSC1 4.4977 6.4641 2.5887 2.6632
NCI-H2722 GDSC1 4.4998 6.872 2.406 3.9052
NCI-H82 GDSC1 4.5036 7.2661 2.2261 5.1724
NCI-H2595 GDSC1 4.5116 15.3525 -1.7329 26.8585
NCI-H2347 GDSC1 4.5268 7.1182 2.3092 4.5273
SBC-1 GDSC1 4.563 6.5084 2.6055 2.4352
NCI-H292 GDSC1 4.5637 8.7477 1.5612 9.7961
EMC-BAC-2 GDSC1 4.6282 7.0544 2.3991 3.686
NCI-H209 GDSC1 4.6469 9.305 1.3497 11.0368
NCI-H446 GDSC1 4.6542 7.6468 2.1432 5.4159
NCI-H2444 GDSC1 4.6567 5.6498 2.997 0.2873
LC-1/sq GDSC1 4.7114 9.6273 1.2387 11.61
NCI-H1876 GDSC1 4.7224 9.1768 1.4634 10.0503
SBC-5 GDSC1 4.7266 5.828 2.9595 0.369
NCI-H69 GDSC1 4.7347 8.0943 1.9853 6.3485
IST-SL1 GDSC1 4.7386 8.9145 1.6 9.0589
CPC-N GDSC1 4.7533 7.0834 2.4575 3.0548
NCI-H211 GDSC1 4.7868 9.0998 1.5437 9.325
EBC-1 GDSC1 4.7967 7.8537 2.1353 5.1541
COR-L279 GDSC1 4.8505 6.9097 2.5848 2.0934
NCI-H810 GDSC1 4.8616 6.4741 2.7695 1.0617
LC-2/ad GDSC1 4.8746 7.2375 2.4566 2.8466
Lu-165 GDSC1 4.8748 6.7728 2.6544 1.6551
NCI-H1666 GDSC1 4.9038 8.8231 1.7514 7.589
NCI-H2227 GDSC1 4.9078 7.0179 2.5683 2.1058
COR-L321 GDSC1 4.9135 6.4146 2.8159 0.7931
NCI-H526 GDSC1 4.9147 6.267 2.8726 0.5576
NCI-H2081 GDSC1 4.9302 7.6213 2.3184 3.6409
NCI-H1341 GDSC1 4.9499 6.6295 2.7479 1.0732
NCI-H1581 GDSC1 4.9688 6.9393 2.6316 1.6575
COLO 668 GDSC1 4.9693 7.3204 2.4712 2.5977
NCI-H1792 GDSC1 4.9914 7.29 2.4958 2.4127
IA-LM GDSC1 5.0042 7.4322 2.4416 2.7241
NCI-H2087 GDSC1 5.0206 7.4392 2.4472 2.6626
NCI-H290 GDSC1 5.0265 7.3692 2.4802 2.4525
LK-2 GDSC1 5.0296 6.8439 2.699 1.2288
NCI-H1993 GDSC1 5.0371 7.2916 2.5186 2.208
NCI-H841 GDSC1 5.0485 6.9116 2.6806 1.3003
NCI-H187 GDSC1 5.0511 6.2666 2.9265 0.2971
EPLC-272H GDSC1 5.0541 7.6665 2.3668 3.1081
NCI-H1694 GDSC1 5.0554 6.6001 2.8054 0.7164
HCC827 GDSC1 5.0592 6.7303 2.757 0.9221
NCI-H1105 GDSC1 5.0734 6.8615 2.7119 1.1186
LCLC-103H GDSC1 5.0754 6.4847 2.8568 0.5047
NCI-H1155 GDSC1 5.0756 6.6574 2.7921 0.7549
UMC-11 GDSC1 5.0879 6.9986 2.6639 1.3402
DMS 79 GDSC1 5.1172 7.0114 2.6723 1.2653
COR-L88 GDSC1 5.1227 7.4992 2.4745 2.3413
NCI-H838 GDSC1 5.1368 6.6449 2.8222 0.589
NCI-H1703 GDSC1 5.1576 7.0541 2.6737 1.2152
NCI-H524 GDSC1 5.1588 7.0704 2.6677 1.2429
ChaGo-K-1 GDSC1 5.1716 7.5443 2.4802 2.2369
NCI-H2369 GDSC1 5.1851 6.7729 2.7941 0.6609
NCI-H1092 GDSC1 5.1908 7.6927 2.4274 2.518
NCI-H2023 GDSC1 5.2282 7.4055 2.5652 1.6879
NCI-H1568 GDSC1 5.2314 8.0894 2.2785 3.3627
LCLC-97TM1 GDSC1 5.2335 8.1939 2.2341 3.6395
NCI-H460 GDSC1 5.2354 6.5419 2.898 0.2918
NCI-H720 GDSC1 5.2529 6.5563 2.8994 0.2807
VMRC-LCD GDSC1 5.2779 7.0653 2.7222 0.8791
COR-L95 GDSC1 5.2971 6.7552 2.8452 0.4124
Ms-1 GDSC1 5.3336 6.75 2.861 0.348
NCI-H146 GDSC1 5.3375 7.6105 2.5336 1.7221
NCI-H1836 GDSC1 5.3494 6.818 2.8427 0.3929
NCI-H2066 GDSC1 5.3503 7.043 2.7607 0.6683
DMS 114 GDSC1 5.3547 7.7714 2.4761 2.0099
SW1271 GDSC1 5.4108 7.7505 2.5115 1.7503
NCI-H2029 GDSC1 5.412 6.8255 2.8637 0.3062
NCI-H1573 GDSC1 5.4342 7.443 2.644 1.0809
NCI-H23 GDSC1 5.4349 8.9784 2.0001 4.7763
NCI-H1975 GDSC1 5.439 7.2066 2.7359 0.6987
NCI-H1435 GDSC1 5.451 7.292 2.7088 0.7941
HCC366 GDSC1 5.4707 7.3364 2.7002 0.8129
NCI-H1781 GDSC1 5.4837 6.8958 2.8654 0.2733
SW1573 GDSC1 5.4977 8.5199 2.2339 3.2042
NCI-H2141 GDSC1 5.5027 7.0817 2.8067 0.422
HCC15 GDSC1 5.5294 9.1577 1.9736 4.7716
NCI-H1436 GDSC1 5.5329 7.1029 2.8106 0.3958
NCI-H2172 GDSC1 5.5479 7.4716 2.6813 0.8289
Lu-135 GDSC1 5.5522 7.3694 2.7213 0.6745
HOP-62 GDSC1 5.5752 7.7295 2.5943 1.1726
Lu-99A GDSC1 5.5773 7.7799 2.5756 1.2553
LOU-NH91 GDSC1 5.5988 7.3196 2.758 0.5205
NCI-H441 GDSC1 5.6058 8.0053 2.4995 1.5889
NCI-H522 GDSC1 5.6132 7.819 2.5761 1.2189
DMS 53 GDSC1 5.6155 7.5395 2.6836 0.7698
HOP-92 GDSC1 5.6386 7.9296 2.5442 1.3408
NCI-H1355 GDSC1 5.6427 8.5346 2.3014 2.5974
NCI-H1623 GDSC1 5.6433 7.7356 2.6212 0.9966
NCI-H835 GDSC1 5.6694 7.9866 2.5355 1.3509
CAL-12T GDSC1 5.6812 7.3819 2.7672 0.4486
NCI-H513 GDSC1 5.6938 7.4924 2.7323 0.5494
NCI-H1048 GDSC1 5.7029 7.2549 2.8203 0.2983
NCI-H1693 GDSC1 5.7106 7.7735 2.635 0.8871
NCI-H1755 GDSC1 5.7604 7.4806 2.7621 0.425
NCI-H520 GDSC1 5.7636 7.6544 2.7006 0.6124
NCI-H2869 GDSC1 5.7707 7.8762 2.6212 0.8957
NCI-H1299 GDSC1 5.7732 7.6835 2.6937 0.6295
NCI-H1563 GDSC1 5.7794 8.0763 2.5487 1.1886
SK-MES-1 GDSC1 5.792 8.7384 2.2902 2.4592
SBC-3 GDSC1 5.7964 7.5239 2.7603 0.4134
PC-14 GDSC1 5.7973 7.3209 2.8316 0.2408
NCI-H596 GDSC1 5.7976 7.198 2.8736 0.1622
ABC-1 GDSC1 5.8078 7.7234 2.6928 0.612
RERF-LC-MS GDSC1 5.8483 7.6831 2.7231 0.4946
SK-LU-1 GDSC1 5.8701 7.619 2.7542 0.3969
NCI-H3255 GDSC1 5.8703 7.7859 2.6945 0.5706
Lu-134-A GDSC1 5.9128 8.7142 2.3572 1.9589
NCI-H2110 GDSC1 5.9352 8.5347 2.4386 1.5391
KNS-62 GDSC1 5.9363 7.6715 2.7603 0.3538
NCI-H2170 GDSC1 5.9376 7.6912 2.7538 0.3694
NCI-H1648 GDSC1 5.9385 8.305 2.529 1.1359
NCI-H2228 GDSC1 5.9545 8.0977 2.6135 0.7937
COR-L105 GDSC1 5.9622 8.79 2.3497 1.9412
NCI-H2818 GDSC1 5.9754 8.1319 2.6093 0.795
COR-L32 GDSC1 5.991 8.082 2.6339 0.6988
NCI-H650 GDSC1 5.9917 7.7586 2.7501 0.357
A-549 GDSC1 5.992 7.8082 2.7328 0.4007
NCI-H2135 GDSC1 6.0015 7.5872 2.8129 0.2175
NCI-H1770 GDSC1 6.0193 7.5299 2.8386 0.1683
IST-SL2 GDSC1 6.0247 8.8513 2.3538 1.8521
A-427 GDSC1 6.04 8.4082 2.5324 1.0401
Calu-6 GDSC1 6.0631 7.5369 2.8514 0.1397
EMC-BAC-1 GDSC1 6.0695 8.786 2.3997 1.5874
NCI-H1915 GDSC1 6.1173 7.7337 2.8038 0.2034
NCI-H2342 GDSC1 6.1252 8.1663 2.6556 0.5544
NCI-H2731 GDSC1 6.1296 8.4052 2.5702 0.8327
Lu-65 GDSC1 6.1357 7.7799 2.7946 0.2153
NCI-H322M GDSC1 6.1432 8.7969 2.4277 1.392
NCI-H2085 GDSC1 6.1684 7.9768 2.7386 0.3189
NCI-H2009 GDSC1 6.1725 8.1333 2.6853 0.4482
RERF-LC-Sq1 GDSC1 6.1822 8.8377 2.4288 1.3524
NCI-H1869 GDSC1 6.1859 8.0834 2.7078 0.3846
NCI-H2373 GDSC1 6.1896 7.9859 2.7431 0.3017
NCI-H358 GDSC1 6.1952 7.96 2.7541 0.2767
NCI-H1838 GDSC1 6.1977 7.8409 2.7956 0.1978
HCC44 GDSC1 6.201 7.9908 2.7455 0.2928
PaCa-3 GDSC1 6.2428 8.4465 2.5998 0.6634
NCI-H1651 GDSC1 6.3243 7.972 2.7953 0.1696
LXF 289 GDSC1 6.3248 7.9597 2.7996 0.163
NCI-H2591 GDSC1 6.3555 8.4427 2.6442 0.4774
NCI-H661 GDSC1 6.5208 8.2812 2.7592 0.1831
NCI-H2405 GDSC1 6.5666 8.6497 2.6494 0.3804
EKVX GDSC1 6.8054 9.5011 2.4362 0.8701
⏷ Show the Full List of 165 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.8906 8.2297 2.0195 5.7529
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-5 GDSC1 4.4036 8.4772 1.5806 10.1033
TE-10 GDSC1 5.1451 7.2883 2.5733 1.7486
KYSE-520 GDSC1 5.1827 7.6136 2.4567 2.3575
EC-GI-10 GDSC1 5.2795 7.4192 2.5838 1.5301
TE-9 GDSC1 5.313 6.6288 2.8962 0.2645
KYSE-70 GDSC1 5.339 6.9167 2.8029 0.525
OE19 GDSC1 5.423 6.5825 2.9512 0.122
COLO 680N GDSC1 5.5348 7.0538 2.8288 0.3449
KYSE-270 GDSC1 5.6361 7.9626 2.5301 1.4092
TE-11 GDSC1 5.6529 7.3939 2.752 0.5094
KYSE-150 GDSC1 5.6658 6.9511 2.9112 0.1318
TE-4 GDSC1 5.7254 7.5291 2.7312 0.5349
KYSE-450 GDSC1 5.7701 7.0332 2.9194 0.1009
OE33 GDSC1 5.8317 7.4059 2.8146 0.2656
TE-1 GDSC1 5.8716 7.6645 2.7386 0.4388
TE-6 GDSC1 5.8757 7.9504 2.6364 0.7642
KYSE-180 GDSC1 5.9235 7.8908 2.6771 0.5961
OE21 GDSC1 6.0032 8.0744 2.6415 0.6661
T.T GDSC1 6.0288 7.7628 2.7622 0.3145
TE-8 GDSC1 6.199 8.2707 2.6463 0.5446
KYSE-510 GDSC1 6.2326 7.6211 2.8808 0.0785
TE-15 GDSC1 6.2923 8.38 2.6427 0.51
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TYK-nu GDSC1 4.1246 6.3306 2.4224 4.6572
OC 314 GDSC1 4.2745 8.8424 1.3097 12.3871
OVISE GDSC1 4.3004 6.0279 2.6712 2.4879
A2780 GDSC1 4.3026 6.4603 2.4752 3.8489
TOV-112D GDSC1 4.3218 10.6564 0.451 17.7144
OAW42 GDSC1 4.3553 5.5489 2.9063 0.9443
OV-90 GDSC1 4.5076 6.4791 2.5877 2.6514
TOV-21G GDSC1 4.5789 6.9677 2.4095 3.7154
OVCAR-4 GDSC1 4.6258 6.8539 2.4877 3.0927
OVTOKO GDSC1 4.6788 8.2908 1.8569 7.3959
FU-OV-1 GDSC1 4.8656 7.0572 2.5297 2.4042
OVK18 GDSC1 4.9525 6.9389 2.6238 1.7224
Kuramochi GDSC1 5.0151 8.1869 2.1136 4.8434
OV56 GDSC1 5.0237 6.0108 3.0055 0.1258
Caov-4 GDSC1 5.2699 7.7198 2.4559 2.2372
ES-2 GDSC1 5.4432 7.0358 2.8004 0.4729
JHOS-2 GDSC1 5.5205 7.281 2.7412 0.6241
EFO-21 GDSC1 5.615 7.417 2.7288 0.6076
SK-OV-3 GDSC1 5.6469 7.0215 2.8807 0.188
RMG-I GDSC1 5.7122 7.9037 2.5862 1.0859
OVCAR-3 GDSC1 5.7242 7.3766 2.7854 0.3777
IGROV-1 GDSC1 5.7507 7.9471 2.586 1.0542
OVCAR-5 GDSC1 5.8251 7.7506 2.6897 0.6121
OVCAR-8 GDSC1 5.9793 7.9084 2.6923 0.5195
EFO-27 GDSC1 6.2398 7.8381 2.8112 0.1632
OAW28 GDSC1 6.2617 8.339 2.6457 0.5159
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SU.86.86 GDSC1 4.778 11.1121 0.5636 15.6832
SUIT-2 GDSC1 4.7808 6.8348 2.5806 2.2272
QGP-1 GDSC1 4.9279 7.3921 2.4181 2.9995
Capan-2 GDSC1 4.9317 7.092 2.5492 2.1838
YAPC GDSC1 5.0346 6.3071 2.9057 0.3666
PaTu 8988t GDSC1 5.0467 6.479 2.8474 0.5585
KP-3 GDSC1 5.0691 7.1897 2.5771 1.8273
Hs 766T GDSC1 5.1406 7.7976 2.3563 3.0288
PaTu 8902 GDSC1 5.2836 6.5913 2.8985 0.2705
CFPAC-1 GDSC1 5.2938 7.3667 2.6114 1.3747
KP-4 GDSC1 5.3265 6.6037 2.9099 0.2274
KP-2 GDSC1 5.3364 6.7029 2.8788 0.299
Panc 03.27 GDSC1 5.3767 7.3524 2.6541 1.0889
DAN-G GDSC1 5.5245 6.9564 2.8592 0.2727
SW1990 GDSC1 5.5409 7.572 2.6402 1.0029
Panc 08.13 GDSC1 5.5819 7.3477 2.7411 0.586
Panc 04.03 GDSC1 5.6058 7.6189 2.6498 0.9096
PL4 GDSC1 5.6364 7.7495 2.6129 1.037
KP-1N GDSC1 5.6534 8.1128 2.4784 1.6412
MZ-PC-1 GDSC1 5.6626 7.7559 2.6216 0.9789
HPAC GDSC1 5.7001 7.2437 2.8232 0.2925
AsPC-1 GDSC1 5.7231 9.7059 1.8392 5.2694
HPAF-II GDSC1 5.8292 7.6983 2.7103 0.5437
Panc 10.05 GDSC1 5.845 7.88 2.65 0.7355
PSN1 GDSC1 5.8759 7.4997 2.7981 0.287
Panc 02.03 GDSC1 6.0109 7.8545 2.7235 0.417
BxPC-3 GDSC1 6.501 8.721 2.6001 0.5316
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 4.703 6.8868 2.5163 2.763
NCI-H2452 GDSC1 5.98 7.9625 2.6731 0.5776
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1 4.1908 7.003 2.1455 6.5477
VCaP GDSC1 4.8126 6.5341 2.7225 1.3616
22Rv1 GDSC1 4.8464 7.6977 2.236 4.3562
DU145 GDSC1 5.9309 8.0882 2.6075 0.8318
PC-3 GDSC1 6.0555 8.1863 2.6212 0.7025
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 5.6847 7.2467 2.8165 0.3145
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB373-MEL-D GDSC1 3.8282 19.7538 -4.476 35.2777
SK-MEL-31 GDSC1 4.0328 6.1982 2.4244 4.8786
COLO 783 GDSC1 4.1408 8.088 1.5821 10.8607
UACC-62 GDSC1 4.1499 7.7049 1.7763 9.4126
IPC-298 GDSC1 4.1644 6.0643 2.5731 3.461
SK-MEL-30 GDSC1 4.2495 6.1412 2.5898 3.1531
COLO 792 GDSC1 4.2627 6.7782 2.3008 5.2095
SK-MEL-5 GDSC1 4.2725 7.9902 1.7247 9.4363
451Lu GDSC1 4.2879 7.8212 1.8176 8.7131
MMAc-SF GDSC1 4.3294 7.366 2.0653 6.7752
G-mel GDSC1 4.4318 7.096 2.2602 5.0955
MeWo GDSC1 4.4687 6.6365 2.4947 3.3548
RVH-421 GDSC1 4.4711 6.5979 2.5136 3.2203
IGR-37 GDSC1 4.4944 6.1192 2.7373 1.7224
A-375 GDSC1 4.5422 6.4176 2.6338 2.2895
WM115 GDSC1 4.5581 6.2075 2.7326 1.6533
WT2-iPS GDSC1 4.5641 6.3901 2.6576 2.1019
SK-MEL-2 GDSC1 4.5769 5.9209 2.8598 0.9244
CP66-MEL GDSC1 4.6036 6.1818 2.7661 1.3936
Mel Ho GDSC1 4.6292 6.7164 2.5505 2.6731
SK-MEL-3 GDSC1 4.6481 6.0751 2.8309 0.9906
COLO 800 GDSC1 4.6607 6.5842 2.6251 2.1459
HT-144 GDSC1 4.661 6.4312 2.6905 1.7493
G-361 GDSC1 4.6943 6.6168 2.6287 2.0698
CHL-1 GDSC1 4.754 6.7172 2.6169 2.0482
LB2518-MEL GDSC1 4.8478 6.0896 2.9115 0.4596
M14 GDSC1 4.8593 6.9528 2.571 2.1628
SK-MEL-28 GDSC1 4.8697 6.0024 2.9519 0.3124
SK-MEL-1 GDSC1 4.9194 6.3702 2.8355 0.7035
GAK GDSC1 5.1693 6.6298 2.8409 0.5004
MZ-MEL-7 GDSC1 5.2382 6.8489 2.7874 0.6476
WM793 GDSC1 5.2948 7.0799 2.7237 0.8581
Hs 940.T GDSC1 5.3232 7.1381 2.7135 0.8771
MZ-MEL-2 GDSC1 5.4019 9.069 1.9409 5.2233
UACC-257 GDSC1 5.5035 7.1241 2.7918 0.4668
Mel JuSo GDSC1 5.5411 7.0222 2.8423 0.3075
WM1552C GDSC1 5.5945 7.322 2.7554 0.5313
COLO 679 GDSC1 5.6125 7.3363 2.7572 0.5153
SK-MEL-24 GDSC1 5.6796 7.2358 2.8184 0.3118
LOX-IMVI GDSC1 5.7613 7.4788 2.7631 0.4219
IST-MEL1 GDSC1 5.8446 7.6802 2.7227 0.4977
SH-4 GDSC1 5.9296 7.6996 2.7479 0.3879
Hs 938.T GDSC1 5.9631 7.5668 2.8063 0.2414
WM278 GDSC1 6.0113 12.7778 0.6034 12.2544
WM35 GDSC1 6.0369 8.2032 2.6076 0.7608
A-431 GDSC1 6.074 7.8583 2.7455 0.3368
A101D GDSC1 6.2542 15.096 -0.3371 16.5872
HMV-II GDSC1 6.2691 8.3489 2.645 0.5144
A-388 GDSC1 6.3363 8.2814 2.6937 0.3615
EquiPSC Line K2 GDSC1 4.2977 7.6725 1.8964 8.1066
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 5.9483 7.8097 2.7159 0.4664
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh30 GDSC1 -2.0062 8.1181 -4.2554 56.7464
Rh41 GDSC1 4.1883 6.1303 2.5573 3.5199
A-204 GDSC1 4.2758 7.7142 1.861 8.4277
SW982 GDSC1 4.4292 6.9098 2.3454 4.4895
SW684 GDSC1 4.4496 6.3579 2.6088 2.6197
MES-SA GDSC1 4.5936 6.1328 2.7815 1.3208
SW872 GDSC1 4.6026 7.4856 2.1859 5.2309
VA-ES-BJ GDSC1 4.6383 6.6618 2.5794 2.4709
Rh18 GDSC1 4.7394 10.8171 0.68 15.0996
SK-UT-1 GDSC1 4.8279 7.0009 2.5341 2.4383
EW-8 GDSC1 4.8624 7.0068 2.5496 2.2874
HT-1080 GDSC1 4.9269 6.3182 2.8584 0.604
G-402 GDSC1 5.1266 9.2743 1.6816 7.5449
SK-LMS-1 GDSC1 5.2573 7.0104 2.7344 0.845
RD GDSC1 5.2988 7.9702 2.3651 2.7252
GCT GDSC1 5.4188 7.0707 2.7781 0.5606
RKN GDSC1 5.5005 6.7009 2.9382 0.1254
G-401 GDSC1 5.5303 8.045 2.4484 1.9379
Hs 633.T GDSC1 5.6404 7.0702 2.8617 0.2274
MFH-ino GDSC1 5.6979 7.5659 2.7071 0.6305
STS-0421 GDSC1 5.8911 8.2387 2.5342 1.154
KYM-1 GDSC1 5.9306 7.3427 2.8709 0.1375
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IM95 GDSC1 -1.3413 49.4569 -23.7384 50.7154
ECC10 GDSC1 3.4079 7.826 1.1411 16.444
NUGC-4 GDSC1 3.5992 5.3886 2.5096 5.4699
HGC-27 GDSC1 4.0629 20.2542 -4.5349 34.785
MKN45 GDSC1 4.8713 6.0084 2.9504 0.3162
RF-48 GDSC1 4.9129 7.1152 2.5296 2.33
Hs 746.T GDSC1 4.9351 6.8401 2.656 1.567
23132/87 GDSC1 5.0222 6.4717 2.84 0.604
MKN1 GDSC1 5.0903 6.4545 2.8738 0.4372
SNU-5 GDSC1 5.1753 6.6057 2.8521 0.459
TGBC11TKB GDSC1 5.2169 10.223 1.2941 9.9237
SCH GDSC1 5.2251 6.9354 2.7494 0.8091
NUGC-3 GDSC1 5.5226 6.9364 2.8655 0.2588
HSC-39 GDSC1 5.585 7.1371 2.8181 0.3516
Fu97 GDSC1 5.7075 7.5534 2.7154 0.5965
SK-GT-2 GDSC1 6.1024 8.5637 2.4996 1.1228
SNU-1 GDSC1 6.1363 8.0797 2.6907 0.4496
RERF-GC-1B GDSC1 6.3614 8.7449 2.5376 0.7984
MKN7 GDSC1 6.3742 8.2568 2.7159 0.2997
SNG-M GDSC1 4.3454 6.5021 2.4822 3.7036
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 4.1535 8.2844 1.495 11.4489
KMH-2 GDSC1 4.5062 6.9138 2.3907 3.9985
BHT-101 GDSC1 4.755 9.7247 1.2219 11.6027
K5 GDSC1 4.8282 6.9739 2.5458 2.3651
TT GDSC1 4.9915 7.7754 2.2845 3.7495
FTC-133 GDSC1 5.1631 6.7687 2.7866 0.707
ASH-3 GDSC1 5.2941 6.6688 2.875 0.3274
WRO GDSC1 5.3741 7.6807 2.5225 1.7365
8305C GDSC1 5.4202 6.7905 2.879 0.265
B-CPAP GDSC1 5.4932 6.9833 2.8382 0.3381
TT2609-C02 GDSC1 5.5628 7.7646 2.5752 1.2713
HTC-C3 GDSC1 5.8352 8.0282 2.5907 0.967
ML-1 [Human leukemia] GDSC1 5.8437 7.7032 2.7141 0.5242
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB771-HNC GDSC1 4.0517 8.2861 1.4187 12.3069
HSC-4 GDSC1 4.2089 14.0679 -1.3309 26.3568
BB49-HNC GDSC1 4.2908 6.4941 2.4522 4.0405
BICR 78 GDSC1 4.3463 6.2829 2.583 2.9977
HSC-2 GDSC1 4.3731 6.2932 2.594 2.8681
SKN-3 GDSC1 4.6429 6.6718 2.5776 2.4747
Ca9-22 GDSC1 4.6554 8.4079 1.7859 7.9602
JHU-022 GDSC1 5.061 8.1916 2.1383 4.5858
CAL-27 GDSC1 5.0612 6.8038 2.7292 1.0486
PCI-30 GDSC1 5.0741 8.5015 2.0057 5.4527
SCC-9 GDSC1 5.0855 6.8192 2.7339 1.0024
PCI-38 GDSC1 5.0874 7.2502 2.561 1.8931
SAS GDSC1 5.1032 7.7225 2.3689 3.0127
HSC-3 GDSC1 5.1196 6.6684 2.8063 0.6623
Detroit 562 GDSC1 5.1561 6.9141 2.7279 0.9626
BICR 10 GDSC1 5.1751 7.0052 2.7007 1.0685
SCC-4 GDSC1 5.3745 7.1675 2.724 0.7928
UPCI-SCC-090 GDSC1 5.4184 7.9918 2.4162 2.2577
PCI-04B GDSC1 5.4652 8.6266 2.171 3.6408
KOSC-2 GDSC1 5.4821 7.7985 2.5253 1.5965
KON GDSC1 5.4955 7.2327 2.749 0.6128
OSC-20 GDSC1 5.5279 7.2154 2.7682 0.5283
PCI-06A GDSC1 5.5553 7.8229 2.549 1.4019
PCI-15A GDSC1 5.596 7.6676 2.6271 1.0115
SCC-15 GDSC1 5.6435 7.5779 2.6807 0.7607
SCC-25 GDSC1 5.7112 7.6756 2.6719 0.7464
BHY GDSC1 5.8283 7.4768 2.7887 0.3263
HO-1-N-1 GDSC1 5.8616 7.588 2.762 0.3802
PE/CA-PJ15 GDSC1 5.9186 7.4056 2.8456 0.1804
BICR 22 GDSC1 5.9192 7.3871 2.852 0.1694
NCI-H3118 GDSC1 5.9222 8.2791 2.5319 1.1371
HO-1-u-1 GDSC1 5.9523 7.5724 2.8005 0.2566
OSC-19 GDSC1 5.9621 7.3973 2.8635 0.1421
JHU-011 GDSC1 6.2423 8.2592 2.6668 0.4667
JHU-029 GDSC1 6.5689 8.903 2.5609 0.6102
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC1 3.4821 6.6299 1.7994 11.3798
SW780 GDSC1 4.3866 8.0669 1.7674 8.8056
HT-1197 GDSC1 4.6514 7.7961 2.072 5.9287
639V GDSC1 5.1625 6.1964 2.9911 0.1165
J82 GDSC1 5.3689 7.9834 2.3951 2.4465
CAL-29 GDSC1 5.4498 7.0164 2.8099 0.4397
647V GDSC1 5.4948 6.7091 2.9335 0.1341
RT-4 GDSC1 5.5331 7.3573 2.718 0.6993
TCCSUP GDSC1 5.6443 7.2468 2.8014 0.3699
RT-112 GDSC1 5.6807 7.3502 2.7784 0.4167
SW1710 GDSC1 5.7506 8.1995 2.488 1.4923
5637 GDSC1 5.899 7.5405 2.7923 0.292
UM-UC-3 GDSC1 6.0616 7.5331 2.8522 0.1388
T24 GDSC1 6.3047 8.7375 2.5176 0.9049
HT-1376 GDSC1 6.3412 8.0188 2.7854 0.1812
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC1 3.0731 7.7536 0.8955 19.3663
NT2-D1 GDSC1 3.8661 6.248 2.2839 6.409
OVCA420 GDSC1 3.9509 7.4961 1.733 10.3342
SW962 GDSC1 3.9517 8.8498 1.0637 15.0809
BPH-1 GDSC1 4.0334 6.5712 2.2453 6.2268
JEG-3 GDSC1 4.0592 5.801 2.6298 3.2949
SiHa GDSC1 4.4567 11.026 0.3699 17.7609
MS751 GDSC1 4.6794 6.3238 2.7446 1.4126
Ca Ski GDSC1 4.6902 7.1561 2.3894 3.6283
SKN GDSC1 4.7642 7.564 2.2482 4.4416
OV17R GDSC1 4.801 7.9039 2.1148 5.2877
HeLa GDSC1 4.8208 5.7593 3.0195 0.1574
LB831-BLC GDSC1 4.8764 7.1702 2.4868 2.653
C-33 A GDSC1 5.0817 7.3197 2.5292 2.0816
PEO1 GDSC1 5.1803 7.7909 2.3802 2.8183
SKG-IIIa GDSC1 5.4687 7.2694 2.7246 0.7201
HEC-1 GDSC1 5.4732 7.329 2.704 0.796
DSH1 GDSC1 5.4763 7.4015 2.6779 0.8987
HT-3 GDSC1 5.492 7.582 2.6152 1.1561
SW756 GDSC1 5.5203 7.1226 2.7988 0.4366
PWR-1E GDSC1 5.5406 7.5134 2.6625 0.9101
OVCA433 GDSC1 5.5672 8.551 2.2565 2.9639
ME-180 GDSC1 5.5902 9.9196 1.6669 6.6343
KGN GDSC1 5.6875 7.7811 2.6225 0.9551
JAR GDSC1 5.694 7.3287 2.7911 0.3758
NEC8 GDSC1 5.8039 7.1633 2.8875 0.1388
OMC-1 [Human cervical carcinoma] GDSC1 5.8816 7.7406 2.7152 0.5012
SiSo GDSC1 5.9693 7.4945 2.8332 0.1894
CAL-39 GDSC1 6.0604 8.0913 2.6577 0.582
ACC-OV7 GDSC1 6.3386 8.5195 2.6105 0.5799
JHOS-3 GDSC1 6.5196 8.4076 2.716 0.2568
OVMIU GDSC1 6.5897 8.8361 2.5925 0.5123
UWB1.289 GDSC1 6.6246 9.0802 2.5185 0.7086
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug

References

1 CBP and p300: HATs for different occasions. Biochem Pharmacol. 2004 Sep 15;68(6):1145-55.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2734).
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2735).