Details of the Drug

General Information of Drug (ID: DMQXO1I)

• Drug Name: Salicylamide
• Synonyms: Sodium salicylamide; SALICYLAMIDE SODIUM; UNII-OZV98V4536; 2-Hydroxybenzamide monosodium salt; Salicylamide, monosodium salt; OZV98V4536; sodium 2-carbamoylphenolate; Benzamide, 2-hydroxy-, monosodium salt; 2-(Sodiooxy)benzamide; 87-17-2 (Parent); 65-45-2 (Parent); Sodium 2-(anilinocarbonyl)phenolate; EINECS 219-990-2; 36205-82-0; LS-144175; Benzamide, 2-hydroxy-, monosodium salt (9CI); Benzamide, 2-hydroxy-N-phenyl-, monosodium salt

Indication

Disease Entry	ICD 11	Status	REF
Back pain	ME84.Z	Approved	[1]
Fever	MG26	Approved	[2]
Headache	8A80-8A84	Approved	[3]
Pain	MG30-MG3Z	Approved	[4]

• Affected Organisms: Humans and other mammals
• ATC Code:
  N02BA05: Salicylamide
  N02BA: Salicylic acid and derivatives
  N02B: OTHER ANALGESICS AND ANTIPYRETICS
  N02: ANALGESICS
  N: NERVOUS SYSTEM
• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C7H7NO2
  Canonical SMILES: C1=CC=C(C(=C1)C(=O)N)O
  InChI: InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
  InChIKey: SKZKKFZAGNVIMN-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 5147
  ChEBI ID: CHEMBL27577
  CAS Number: 65-45-2
  UNII: EM8BM710ZC
  DrugBank ID: DB08797
  TTD ID: D07MCK
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

References

• [1] Augmentation of musculoskeletal soft tissue morphology within low back pain patients may suggest the presence of physiological stress shielding: An in vivo study. J Biomech. 2024 Jan;162:111894.
• [2] The influence of pyrogen-induced fever on salicylamide metabolism in man. J Clin Invest. 1972 Nov;51(11):2959-66.
• [3] Evaluation of acetaminophen-salicylamide combinations in treatment of headache. J Clin Pharmacol J New Drugs. 1967 May-Jun;7(3):150-5.
• [4] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015