Details of the Drug

General Information of Drug (ID: DMR0U4V)

Drug Name
XEN-D0103
Synonyms KCNA voltage-gated potassium channel-5 inhibitor (atrial fibrillation), Xention
Indication
Disease Entry ICD 11 Status REF
Atrial fibrillation BC81.3 Phase 1 [1]
Cross-matching ID
TTD ID
D05DXT

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Voltage-gated potassium channel Kv1.5 (KCNA5) TTW0CMT KCNA5_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT02390258) Fed-Fasted, Single and Multiple Ascending Dose Trial of XEN-D0103. U.S. National Institutes of Health.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 542).