Details of the Drug

General Information of Drug (ID: DMR6LXM)

Drug Name
CAP-232
Synonyms
TT-232; UNII-49D4Q4254Z; TT 232; 49D4Q4254Z; 147159-51-1; Phe-cys-tyr-trp-lys-cys-thr-NH2 (2-6)-disulfide; TLN 232; CAP-232; CAP 232; Phenylalanyl-cysteinyl-tyrosyl-tryptophyl-lysyl-cysteinyl-threoninamide (2-6)-disulfide; AC1OCF7X; CHEMBL539934; TLN-232; L-Threoninamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-cysteinyl-, cyclic (2-6)-disulfide; TT2-32; ZINC169289417; AKOS024458270; DB12088; NCGC00249606-01
Indication
Disease Entry ICD 11 Status REF
Renal cell carcinoma 2C90 Phase 2a [1]
Pain MG30-MG3Z Phase 2 [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 4 Molecular Weight (mw) 947.1
Logarithm of the Partition Coefficient (xlogp) 0.5
Rotatable Bond Count (rotbonds) 16
Hydrogen Bond Donor Count (hbonddonor) 12
Hydrogen Bond Acceptor Count (hbondacc) 13
Chemical Identifiers
Formula
C45H58N10O9S2
IUPAC Name
(4R,7S,10R,13S,16R)-7-(4-aminobutyl)-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-16-[[(2R)-2-amino-3-phenylpropanoyl]amino]-13-[(4-hydroxyphenyl)methyl]-10-(1H-indol-3-ylmethyl)-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetrazacycloheptadecane-4-carboxamide
Canonical SMILES
C[C@H]([C@@H](C(=O)N)NC(=O)[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)[C@@H](CC5=CC=CC=C5)N)O
InChI
InChI=1S/C45H58N10O9S2/c1-25(56)38(39(48)58)55-45(64)37-24-66-65-23-36(53-40(59)31(47)19-26-9-3-2-4-10-26)44(63)51-34(20-27-14-16-29(57)17-15-27)42(61)52-35(21-28-22-49-32-12-6-5-11-30(28)32)43(62)50-33(41(60)54-37)13-7-8-18-46/h2-6,9-12,14-17,22,25,31,33-38,49,56-57H,7-8,13,18-21,23-24,46-47H2,1H3,(H2,48,58)(H,50,62)(H,51,63)(H,52,61)(H,53,59)(H,54,60)(H,55,64)/t25-,31-,33+,34+,35-,36+,37+,38+/m1/s1
InChIKey
SNAJPQVDGYDQSW-DYCFWDQMSA-N
Cross-matching ID
PubChem CID
6918265
CAS Number
147159-51-1
UNII
49D4Q4254Z
DrugBank ID
DB12088
TTD ID
D09EFC
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pyruvate kinase M2 (PKM) TT4LOT8 KPYM_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 5.921 10.3518 2.5128 9.1947
G-292 clone A141B1 GDSC1 2.718 4.1211 2.622 20.671
EW-3 GDSC1 2.7783 3.9356 2.7249 19.6375
EW-22 GDSC1 2.8173 3.6221 2.8054 18.8831
CAL-78 GDSC1 2.831 3.4035 2.8293 18.6471
CHSA8926 GDSC1 2.9243 3.6797 2.9127 17.5433
HuO9 GDSC1 3.0613 4.0646 3.0069 16.1081
SaOS-2 GDSC1 3.1687 4.4425 3.0285 15.3442
EW-13 GDSC1 3.3003 4.4115 3.1813 13.5583
U2OS GDSC1 3.4191 4.4389 3.3024 12.0605
ES8 GDSC1 3.5328 4.3315 3.4581 10.3553
SK-PN-DW GDSC1 3.5512 4.4246 3.4507 10.3014
SK-ES-1 GDSC1 3.5758 5.5322 3.0207 13.3249
CADO-ES1 GDSC1 3.5933 4.5839 3.4425 10.1283
ES1 GDSC1 3.5966 4.5682 3.4517 10.0465
HuO-3N1 GDSC1 3.6203 4.7297 3.4161 10.1748
CAL-72 GDSC1 3.6244 4.7731 3.4031 10.2473
EW-16 GDSC1 3.7469 4.5857 3.6067 8.1441
NOS-1 [Human HNSCC] GDSC1 3.768 4.6096 3.6202 7.936
EW-7 GDSC1 3.77 4.4454 3.6818 7.4899
ES4 GDSC1 3.8241 4.8072 3.598 7.813
ES6 GDSC1 3.8492 5.3603 3.3705 9.4109
NY GDSC1 3.9368 4.9813 3.6344 7
ES7 GDSC1 3.9924 5.2753 3.5489 7.4051
MG-63 GDSC1 4.316 5.4956 3.7301 4.6888
EW-24 GDSC1 4.9766 7.2779 3.3476 5.6085
HOS GDSC1 5.1931 11.1961 1.5812 17.3559
SJSA-1 GDSC1 5.3336 7.6184 3.4212 4.1653
MHH-ES-1 GDSC1 5.5324 10.6937 2.0799 13.1746
A-673 GDSC1 6.4579 7.7863 3.8941 0.2177
TC-71 GDSC1 6.6971 8.2352 3.825 0.2892
EW-1 GDSC1 7.4958 9.4644 3.688 0.3195
EW-18 GDSC1 7.6869 16.9864 0.5267 16.2236
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 152 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 4.0664 4.8114 3.8414 4.8295
IM-9 GDSC1 0.7396 2.5642 0.7177 44.8661
NU-DUL-1 GDSC1 2.736 3.529 2.7272 19.8798
BC-1 GDSC1 2.8378 3.7307 2.8172 18.682
SU-DHL-5 GDSC1 3.0761 3.6267 3.0726 15.5947
RPMI-8866 GDSC1 3.1918 4.4845 3.0406 15.1317
CML-T1 GDSC1 3.2139 5.2279 2.7848 16.8374
Ramos.2G6.4C10 GDSC1 3.325 4.0254 3.2982 12.6324
RCH-ACV GDSC1 3.4106 4.6892 3.2074 12.772
Ku812 GDSC1 3.4478 4.9757 3.1346 13.1023
HH [Human lymphoma] GDSC1 3.4515 4.555 3.2995 11.902
H9 GDSC1 3.5153 4.1993 3.4719 10.3634
SU-DHL-6 GDSC1 3.5476 4.8987 3.2712 11.5991
Karpas-231 GDSC1 3.6043 4.5086 3.4808 9.7997
BL-41 GDSC1 3.6175 4.9887 3.3062 10.9913
CTB-1 GDSC1 3.6682 4.5538 3.534 9.0794
SU-DHL-4 GDSC1 3.6964 4.2609 3.6549 8.0893
L-540 GDSC1 3.7252 5.4481 3.2079 11.2157
QIMR-WIL GDSC1 3.7323 6.0032 2.9505 13.1492
RPMI-6666 GDSC1 3.7383 4.6086 3.5888 8.3172
BV-173 GDSC1 3.7737 5.3795 3.2876 10.3868
GA-10 GDSC1 3.8165 4.9053 3.5474 8.2254
SU-DHL-16 GDSC1 3.8398 4.4122 3.7686 6.5016
AMO1 GDSC1 3.8549 4.4052 3.7872 6.2893
MLMA GDSC1 3.8729 5.6771 3.2415 10.299
EB2 GDSC1 3.8927 4.7523 3.6927 6.7735
JSC-1 GDSC1 3.949 5.0119 3.6322 6.9602
WIL2 NS GDSC1 3.9532 5.0641 3.6119 7.0956
ST486 GDSC1 3.9899 4.9541 3.6994 6.2613
697 GDSC1 3.9936 5.6887 3.3488 8.9526
SUP-HD1 GDSC1 4.056 5.2326 3.6296 6.5062
KOPN-8 GDSC1 4.085 7.5821 2.4904 15.1754
SR GDSC1 4.0865 5.55 3.5021 7.3718
Hs 445 GDSC1 4.2161 5.9831 3.4016 7.6505
MEG-01 GDSC1 4.2341 5.447 3.6846 5.3535
HDLM-2 GDSC1 4.2581 5.4879 3.685 5.2594
P32/ISH GDSC1 4.2609 5.2617 3.8003 4.34
P30/OHK GDSC1 4.2707 5.5725 3.6534 5.4606
Reh GDSC1 4.3485 5.9209 3.5444 6.0364
OCI-Ly19 GDSC1 4.4008 5.7869 3.6541 4.9883
Karpas-620 GDSC1 4.4034 5.666 3.7165 4.488
SU-DHL-10 GDSC1 4.4526 5.3895 3.8928 2.94
KCL-22 GDSC1 4.4926 12.7539 0.2473 26.4558
MOLT-16 GDSC1 4.533 6.3769 3.4646 6.0338
SU-DHL-8 GDSC1 4.55 5.7183 3.8035 3.3333
L-428 GDSC1 4.609 6.9948 3.2166 7.7251
HAL-01 GDSC1 4.6403 8.5519 2.4661 13.3164
DEL GDSC1 4.6822 6.3931 3.5691 4.753
JJN-3 GDSC1 4.6873 5.9061 3.8098 2.8917
EHEB GDSC1 4.6947 6.48 3.5356 4.9745
Granta-519 GDSC1 4.7395 10.944 1.3521 20.2057
KM-H2 GDSC1 4.8406 6.4447 3.6555 3.648
VAL GDSC1 4.8756 6.5349 3.6359 3.7032
HC-1 GDSC1 4.8911 6.8388 3.5005 4.6837
LC4-1 GDSC1 4.8969 7.3663 3.2483 6.5918
SIG-M5 GDSC1 4.9387 7.6139 3.1574 7.1641
NALM-6 GDSC1 4.9552 6.758 3.5826 3.8966
EJM GDSC1 4.9822 6.7085 3.6238 3.5231
DoHH2 GDSC1 4.99 8.1879 2.9135 8.8631
L-363 GDSC1 5.0031 7.6366 3.1922 6.7136
Sc-1 GDSC1 5.0359 7.4721 3.2949 5.8453
NOMO-1 GDSC1 5.0607 6.669 3.692 2.8434
U266B1 GDSC1 5.0687 6.8245 3.6247 3.3093
MHH-PREB-1 GDSC1 5.0739 7.8987 3.1149 7.099
RC-K8 GDSC1 5.1087 6.7294 3.6935 2.7271
ATN-1 GDSC1 5.1655 7.4913 3.3731 4.9196
JURL-MK1 GDSC1 5.1867 7.1589 3.543 3.6261
HT GDSC1 5.2154 7.3338 3.4795 4.0184
SU-DHL-1 GDSC1 5.246 6.9315 3.6831 2.5139
MOLP-8 GDSC1 5.2483 7.1083 3.6042 3.0551
SCC-3 GDSC1 5.2611 6.8859 3.7122 2.2876
Karpas-422 GDSC1 5.3087 7.3665 3.5223 3.5009
CA46 GDSC1 5.3158 8.4847 2.9993 7.2984
MC116 GDSC1 5.3418 6.2998 3.9992 0.5016
EoL-1 GDSC1 5.357 8.3528 3.0901 6.5212
BALL-1 GDSC1 5.36 7.655 3.4205 4.1097
L-1236 GDSC1 5.5629 8.1854 3.3003 4.5104
OPM-2 GDSC1 5.5645 6.9525 3.8414 1.0337
NK-92MI GDSC1 5.5901 7.0597 3.8099 1.1696
DND-41 GDSC1 5.6056 10.9002 2.0315 13.2788
ML-2 GDSC1 5.6516 7.4882 3.6614 1.9378
KY821 GDSC1 5.6738 8.5744 3.1889 5.0495
YT GDSC1 5.6825 7.6428 3.6114 2.1952
RS4;11 GDSC1 5.6929 8.272 3.3386 3.9685
OCI-AML-5 GDSC1 5.6969 6.7911 3.9612 0.3817
THP-1 GDSC1 5.6979 7.8913 3.5115 2.8033
OCI-AML-3 GDSC1 5.7152 7.551 3.6675 1.8053
WSU-DLCL2 GDSC1 5.7647 6.9734 3.921 0.4819
NB4 GDSC1 5.8181 7.0674 3.9077 0.494
GR-ST GDSC1 5.8205 10.6295 2.3128 10.8156
SKM-1 GDSC1 5.8373 7.1977 3.8665 0.6421
HEL GDSC1 5.8404 7.807 3.6231 1.8828
Farage GDSC1 5.8935 7.3266 3.8412 0.7015
TK [Human B-cell lymphoma] GDSC1 5.9019 7.4368 3.8023 0.8652
P31/FUJ GDSC1 5.9075 7.0462 3.9507 0.2969
ARH-77 GDSC1 5.9323 7.6633 3.7264 1.1993
Karpas-299 GDSC1 5.996 7.5591 3.7958 0.8075
KMS-11 GDSC1 6.0054 9.3096 3.0522 5.2804
ME1 GDSC1 6.0266 7.1005 3.9757 0.184
LAMA-84 GDSC1 6.0615 9.0715 3.1923 4.2252
EM-2 GDSC1 6.0944 7.6001 3.8216 0.6216
HL-60 GDSC1 6.1042 7.6282 3.8151 0.6397
MV4-11 GDSC1 6.1053 8.5052 3.463 2.435
RL GDSC1 6.1265 7.4191 3.9006 0.3345
Daudi GDSC1 6.1311 7.7782 3.7695 0.8031
SUP-T1 GDSC1 6.1386 8.0728 3.6575 1.3154
U-698-M GDSC1 6.1509 8.0271 3.6813 1.185
LP-1 GDSC1 6.1605 8.0086 3.693 1.1196
K-562 GDSC1 6.1858 7.7551 3.8011 0.6336
MN-60 GDSC1 6.2115 8.1239 3.6704 1.175
Raji GDSC1 6.2178 7.4738 3.9154 0.2546
DB GDSC1 6.2288 8.2328 3.6351 1.3282
ALL-SIL GDSC1 6.2521 7.7974 3.8122 0.5478
A3/Kawakami GDSC1 6.2538 19.3131 -1.6308 27.5972
P12-Ichikawa GDSC1 6.2775 7.4348 3.9505 0.1587
BE-13 GDSC1 6.2854 8.1118 3.7075 0.9355
Jurkat GDSC1 6.2911 8.3645 3.6111 1.3793
SK-MM-2 GDSC1 6.3035 8.1224 3.7112 0.9038
JVM-3 GDSC1 6.3039 8.195 3.6833 1.0252
OCI-AML-2 GDSC1 6.3056 7.6518 3.8853 0.295
RPMI-8226 GDSC1 6.3516 8.115 3.7343 0.7697
SUP-M2 GDSC1 6.3543 7.6289 3.9112 0.215
MOLT-4 GDSC1 6.3778 8.082 3.7574 0.6614
OCI-M1 GDSC1 6.3856 7.5097 3.9628 0.1123
KMS-12-BM GDSC1 6.3902 8.2973 3.6811 0.9577
SUP-B15 GDSC1 6.4002 7.8322 3.8569 0.3292
TUR GDSC1 6.4057 7.5555 3.9543 0.1209
Jiyoye GDSC1 6.5166 8.4447 3.6784 0.8644
MY-M12 GDSC1 6.5215 8.3112 3.7304 0.6621
MOLT-13 GDSC1 6.535 8.6161 3.6207 1.092
KMOE-2 GDSC1 6.5698 8.3077 3.751 0.5603
BC-3 GDSC1 6.5707 8.0273 3.8514 0.2742
WSU-NHL GDSC1 6.5766 8.7532 3.5857 1.2102
KE-37 GDSC1 6.6011 8.0165 3.8661 0.2307
CTV-1 GDSC1 6.6326 11.0777 2.6202 6.8499
MOLM-13 GDSC1 6.6534 8.3673 3.7619 0.4788
Loucy GDSC1 6.6561 8.0959 3.8585 0.2292
CCRF-CEM GDSC1 6.7445 8.3038 3.8184 0.2874
DG-75 GDSC1 6.7765 8.5638 3.7384 0.4857
VL51 GDSC1 6.7985 8.5566 3.7494 0.4428
Karpas-45 GDSC1 6.8764 8.4981 3.7989 0.2852
CESS GDSC1 6.9816 8.5435 3.8208 0.2083
RPMI-8402 GDSC1 7.0058 8.5713 3.8199 0.2036
NKM-1 GDSC1 7.0166 9.3746 3.5353 1.0467
KG-1 GDSC1 7.0225 8.7346 3.7697 0.2997
PF-382 GDSC1 7.0339 8.815 3.7459 0.3508
ROS-50 GDSC1 7.1001 8.7649 3.7871 0.239
ALL-PO GDSC1 7.1826 9.3603 3.6077 0.6723
GDM-1 GDSC1 7.2037 8.9714 3.7532 0.2759
JVM-2 GDSC1 7.2158 9.4297 3.5954 0.6929
PL-21 GDSC1 7.2892 9.3149 3.6646 0.4521
Mono-Mac-6 GDSC1 7.3659 9.9178 3.4754 1.0181
⏷ Show the Full List of 152 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-GT-4 GDSC1 3.2996 4.354 3.1973 13.4526
KYSE-220 GDSC1 4.1147 5.2699 3.6658 5.9778
KYAE-1 GDSC1 5.1312 7.2817 3.4499 4.4376
OACP4 C GDSC1 5.3504 7.4999 3.4863 3.6637
FLO-1 GDSC1 5.6225 8.5945 3.1477 5.4569
TE-12 GDSC1 6.1333 10.613 2.5274 8.5735
OACM5.1 C GDSC1 6.4042 8.7303 3.5166 1.7316
HCE-4 GDSC1 6.5818 8.4744 3.6942 0.754
KYSE-50 GDSC1 6.8439 8.7037 3.714 0.5243
ESO-26 GDSC1 7.0792 8.8688 3.7437 0.339
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 4.4431 6.6212 3.2716 7.8516
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-YS GDSC1 2.146 3.2512 2.1329 27.2812
IMR-5 GDSC1 2.4534 3.2498 2.4493 23.3824
MHH-NB-11 GDSC1 2.6495 3.4133 2.6439 20.9407
NB(TU)1 GDSC1 2.723 3.6608 2.7033 20.1107
SJNB-14 GDSC1 2.8157 3.5275 2.8096 18.8658
SJNB-6 GDSC1 2.8886 4.7072 2.6378 19.5985
NB1 GDSC1 2.9885 3.6411 2.9819 16.7099
NB69 GDSC1 3.0092 3.8014 2.9908 16.5258
CHP-134 GDSC1 3.0606 3.7206 3.0517 15.8229
TGW GDSC1 3.2054 4.0105 3.1722 14.1691
LA-N-6 GDSC1 3.2122 4.1747 3.1477 14.2893
SK-N-SH GDSC1 3.2904 4.1158 3.245 13.1868
SJNB-12 GDSC1 3.2961 4.5114 3.1455 13.828
Kelly GDSC1 3.3085 4.0796 3.2714 12.9063
SJNB-10 GDSC1 3.328 4.314 3.2394 13.0052
SK-N-MC-IXC GDSC1 3.5086 4.1479 3.4751 10.382
CHP-212 GDSC1 3.576 4.4699 3.4631 10.0783
KP-N-YN GDSC1 3.7094 5.2587 3.2798 10.7438
SJNB-7 GDSC1 3.7825 4.4265 3.7017 7.2827
SK-N-AS GDSC1 3.814 4.5895 3.677 7.2884
SK-N-FI GDSC1 4.0621 5.7392 3.3866 8.3741
SJNB-5 GDSC1 4.2119 5.1071 3.8342 4.2641
SJNB-17 GDSC1 4.3904 7.6889 2.6952 12.4972
GOTO GDSC1 4.5284 6.4225 3.4384 6.2545
SK-N-DZ GDSC1 4.9224 6.9891 3.4495 4.9846
SK-N-BE(2)-M17 GDSC1 5.0019 6.6735 3.653 3.2613
NH-12 GDSC1 5.8915 9.8717 2.7207 7.8323
SJNB-13 GDSC1 6.6306 8.437 3.7276 0.6019
SiMa GDSC1 6.8598 8.9535 3.6288 0.8025
GI-ME-N GDSC1 6.8942 9.1725 3.5607 1.0412
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 4.2595 5.2611 3.7994 4.3533
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 824 GDSC1 2.7186 3.7239 2.6919 20.2108
HCC38 GDSC1 2.7574 4.8287 2.4535 21.5957
BT-549 GDSC1 2.7762 3.7326 2.752 19.475
HCC1187 GDSC1 2.8246 3.3418 2.8238 18.7215
HCC1419 GDSC1 2.8277 3.4089 2.8259 18.689
HCC1395 GDSC1 2.9046 4.2133 2.8034 18.3759
HCC1569 GDSC1 3.091 4.4657 2.9367 16.4105
HCC1954 GDSC1 3.592 5.0217 3.2656 11.4168
HDQ-P1 GDSC1 3.7238 4.8465 3.4772 9.2019
Hs 578T GDSC1 3.7316 4.8846 3.4691 9.2228
MRK-nu-1 GDSC1 3.7704 5.1716 3.3807 9.6962
HCC1428 GDSC1 3.8874 4.7724 3.6784 6.9051
HCC2157 GDSC1 3.9764 4.7586 3.7756 5.7493
ZR-75-30 GDSC1 4.0875 8.129 2.2197 17.1135
BT-483 GDSC1 4.1449 4.7965 3.9247 3.839
HCC1806 GDSC1 4.1794 6.4373 3.1433 9.8188
YMB-1-E GDSC1 4.1911 5.6141 3.5638 6.4706
EFM-19 GDSC1 4.5015 6.2315 3.5123 5.7635
HCC202 GDSC1 4.5495 6.174 3.578 5.0927
UACC-893 GDSC1 4.6545 11.0194 1.2461 21.0957
DU4475 GDSC1 4.7729 8.4639 2.6138 11.7877
MFM-223 GDSC1 4.9005 8.9638 2.4638 12.4657
HCC2218 GDSC1 5.1851 8.4761 2.9128 8.2991
BT-20 GDSC1 5.1953 7.2828 3.4906 3.9848
OCUB-M GDSC1 5.3997 8.4589 3.068 6.574
MDA-MB-415 GDSC1 5.4038 8.5187 3.0422 6.7525
BT-474 GDSC1 5.9525 8.0774 3.5659 2.0542
MDA-MB-468 GDSC1 5.9659 8.1771 3.5306 2.2427
MDA-MB-361 GDSC1 6.0093 7.6932 3.7494 1.005
CAMA-1 GDSC1 6.016 12.0839 1.746 13.9217
CAL-148 GDSC1 6.109 7.6058 3.8255 0.5964
MDA-MB-453 GDSC1 6.1327 8.432 3.5077 2.133
Evsa-T GDSC1 6.1521 7.6937 3.8102 0.6233
HCC70 GDSC1 6.1822 8.5563 3.4805 2.2199
CAL-120 GDSC1 6.2603 7.5826 3.8929 0.2945
HCC1500 GDSC1 6.3625 8.0844 3.7503 0.6992
MCF-7 GDSC1 6.3794 8.4386 3.6216 1.2362
MDA-MB-330 GDSC1 6.4516 11.2625 2.4251 8.5105
CAL-51 GDSC1 6.5648 7.9468 3.8771 0.2192
EFM-192A GDSC1 6.6507 8.3201 3.7778 0.4331
MDA-MB-231 GDSC1 6.7008 8.6018 3.695 0.6703
UACC-812 GDSC1 6.8011 8.5758 3.7435 0.4584
MDA-MB-157 GDSC1 6.8045 8.6775 3.7082 0.5639
MDA-MB-175-VII GDSC1 6.8274 8.2798 3.8564 0.1845
MDA-MB-436 GDSC1 6.8903 8.3803 3.8443 0.1899
HCC1599 GDSC1 7.0456 8.555 3.8393 0.1613
HCC1937 GDSC1 7.1226 8.8833 3.7544 0.2994
CAL-85-1 GDSC1 7.2211 9.041 3.7354 0.3079
AU565 GDSC1 7.3704 9.5374 3.6161 0.5479
T-47D GDSC1 7.7233 9.7671 3.6652 0.2963
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAS-1 GDSC1 2.9597 3.5619 2.956 17.051
D-392MG GDSC1 2.9771 3.7573 2.9614 16.9096
SF268 GDSC1 3.0493 3.8938 3.0222 16.0806
D-336MG GDSC1 3.0716 4.894 2.7674 17.7007
D-566MG GDSC1 3.3039 4.1293 3.2569 13.0281
SNB-75 GDSC1 3.314 4.1095 3.2718 12.871
U-87MG ATCC GDSC1 3.3477 4.1369 3.3029 12.4662
GB-1 GDSC1 3.4251 4.0821 3.3967 11.3915
D-542MG GDSC1 3.429 4.4118 3.3215 11.8737
KALS-1 GDSC1 3.5138 4.3495 3.4323 10.6382
SK-MG-1 GDSC1 3.5572 4.2825 3.4978 9.9465
DK-MG GDSC1 3.5628 10.6742 0.493 28.9607
KINGS-1 GDSC1 3.5685 4.9261 3.2816 11.4174
NMC-G1 GDSC1 3.5987 4.7536 3.3837 10.5205
YKG-1 GDSC1 3.6475 4.176 3.62 8.6071
SW1783 GDSC1 3.6906 4.6505 3.5218 9.0479
KS-1 [Human Krukenberg tumour] GDSC1 3.706 4.6636 3.5332 8.8853
PFSK-1 GDSC1 3.7384 4.7294 3.5412 8.6607
42-MG-BA GDSC1 3.7422 4.2056 3.7168 7.4104
MOG-G-CCM GDSC1 3.7473 4.6003 3.6016 8.1784
SF539 GDSC1 3.7511 4.2072 3.7261 7.2961
GI-1 GDSC1 3.7912 4.4932 3.6883 7.3284
MOG-G-UVW GDSC1 3.8131 4.8005 3.5895 7.9301
M059J GDSC1 3.8221 4.7434 3.6231 7.6375
SW1088 GDSC1 3.8227 4.4478 3.7382 6.8077
U-118MG GDSC1 3.8608 5.2377 3.4397 8.8297
A-172 GDSC1 3.8941 4.5453 3.7794 6.1336
T98G GDSC1 3.9289 4.7049 3.7505 6.1677
LNZTA3WT4 GDSC1 3.932 4.667 3.7699 6.0091
U-251MG GDSC1 3.9367 4.478 3.8505 5.4012
Daoy GDSC1 3.9501 13.265 -0.4631 30.995
D-423MG GDSC1 4.0245 5.3836 3.5266 7.4392
D283 Med GDSC1 4.04 4.7303 3.8526 4.8672
LN-405 GDSC1 4.0696 4.8531 3.825 4.9396
YH-13 GDSC1 4.1156 4.8347 3.8784 4.3248
D-502MG GDSC1 4.234 5.9048 3.456 7.154
LN-229 GDSC1 4.2623 5.1701 3.8472 3.966
GaMG GDSC1 4.3184 5.1707 3.8947 3.3824
Hs 683 GDSC1 4.3415 5.4156 3.7913 4.1147
Becker GDSC1 4.4108 5.6551 3.7279 4.3728
DBTRG-05MG GDSC1 4.759 6.359 3.6406 3.9815
KNS-42 GDSC1 5.0795 7.1359 3.4852 4.3059
Onda 10 GDSC1 5.0901 6.8771 3.6137 3.3394
KNS-81-FD GDSC1 5.1544 7.799 3.2187 6.0982
LN-18 GDSC1 5.1549 7.2592 3.4759 4.1884
H4 GDSC1 5.2147 7.6145 3.347 4.9894
D-247MG GDSC1 5.2647 7.747 3.3169 5.0864
SF126 GDSC1 5.3363 7.6238 3.4203 4.1652
8-MG-BA GDSC1 5.3707 7.131 3.6651 2.394
Onda 11 GDSC1 5.4102 8.2603 3.1691 5.8091
SF295 GDSC1 5.4952 7.2817 3.6676 2.1553
ONS-76 GDSC1 6.4129 7.8941 3.8397 0.3706
AM-38 GDSC1 6.5662 8.392 3.7185 0.675
D-263MG GDSC1 6.5823 8.1067 3.8278 0.3274
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 4.4712 6.4881 3.3606 7.0563
TGBC1TKB GDSC1 4.6102 6.2267 3.5978 4.7484
TGBC24TKB GDSC1 7.1748 9.5344 3.5405 0.91
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1 4.5734 6.0008 3.6817 4.2082
MFE-319 GDSC1 5.2521 6.8633 3.7172 2.2716
KLE GDSC1 5.3964 8.4125 3.0879 6.4367
MFE-296 GDSC1 5.7744 7.8055 3.5898 2.1808
EN GDSC1 6.2196 7.3206 3.969 0.1403
RL95-2 GDSC1 6.7343 8.1816 3.857 0.2087
AN3-CA GDSC1 6.9354 8.6539 3.7661 0.3399
MFE-280 GDSC1 7.4762 9.4505 3.6858 0.3307
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O GDSC1 2.7782 3.452 2.7742 19.3213
OS-RC-2 GDSC1 2.967 3.5483 2.9638 16.9568
NCC021 GDSC1 3.0799 3.9188 3.0514 15.7066
RXF 393L GDSC1 3.1124 4.2121 3.0303 15.6534
A-704 GDSC1 3.2051 3.9902 3.175 14.1523
769-P GDSC1 3.2208 4.1489 3.1627 14.1401
TK-10 GDSC1 3.2383 4.2306 3.163 14.0352
RCC10RGB GDSC1 3.2424 4.0642 3.2029 13.7474
ACHN GDSC1 3.3775 4.3942 3.2707 12.5113
Caki-1 GDSC1 3.4619 4.4606 3.3421 11.548
KTCTL-140 GDSC1 3.4716 4.6973 3.2699 12.0031
LB2241-RCC GDSC1 3.6777 4.5361 3.5506 8.9117
KMRC-20 GDSC1 3.7105 4.3337 3.6514 8.0311
KMRC-1 GDSC1 3.7198 4.1967 3.6942 7.6912
VMRC-RCZ GDSC1 3.7381 4.5675 3.6041 8.2092
BFTC-909 GDSC1 3.7807 4.4823 3.6808 7.438
SW13 GDSC1 3.8395 4.5327 3.7259 6.8042
SW156 GDSC1 3.8413 4.7815 3.627 7.5134
CAL-54 GDSC1 3.8708 4.4885 3.7759 6.2822
KTCTL-21 GDSC1 3.9032 4.8277 3.6703 6.8888
BB65-RCC GDSC1 4.0765 5.0906 3.7178 5.7344
LB1047-RCC GDSC1 4.1782 5.6816 3.5189 6.8735
UO-31 GDSC1 4.5855 6.1238 3.6301 4.5725
A-498 GDSC1 5.9274 8.3445 3.4385 2.871
KTCTL-195 GDSC1 6.2744 7.8969 3.7843 0.6337
HA7-RCC GDSC1 6.3162 9.1924 3.2792 3.2185
KTCTL-13 GDSC1 6.6098 8.3476 3.7521 0.5333
VMRC-RCW GDSC1 6.7038 8.2959 3.8063 0.3322
SN12C GDSC1 6.9225 8.5233 3.8067 0.253
KTCTL-26A GDSC1 6.9279 8.5756 3.7906 0.2858
KTCTL-1M GDSC1 6.9651 8.9461 3.6733 0.5853
LB996-RCC GDSC1 7.4932 9.4045 3.7077 0.2802
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDST8 GDSC1 3.0942 3.6224 3.0913 15.3652
NCI-H747 GDSC1 3.7454 4.6422 3.5834 8.3187
SNU-C2B GDSC1 3.8352 5.2961 3.3871 9.3479
LS513 GDSC1 3.862 4.3461 3.8132 6.0709
HT-55 GDSC1 3.922 4.5738 3.7979 5.8556
COLO 678 GDSC1 3.9597 4.7306 3.771 5.8639
LS1034 GDSC1 4.1534 4.934 3.8662 4.255
KM12 GDSC1 4.167 5.8697 3.4154 7.7305
SNU-61 GDSC1 4.1846 5.4993 3.6152 6.0918
SNU-407 GDSC1 4.1981 5.088 3.8313 4.3423
SW48 GDSC1 4.2963 6.2749 3.324 7.9615
LS411N GDSC1 4.3133 5.1446 3.9034 3.3322
SW1463 GDSC1 4.3169 5.5002 3.7286 4.6978
HCT 116 GDSC1 4.3352 5.2212 3.8833 3.4113
CCK-81 GDSC1 4.4842 6.1166 3.556 5.4777
COLO205 GDSC1 4.5346 5.8996 3.7026 4.1665
COLO 320HSR GDSC1 4.5717 5.8027 3.778 3.4657
CaR-1 GDSC1 4.7156 6.649 3.4679 5.4361
NCI-H716 GDSC1 4.8599 6.5024 3.6409 3.7068
LS180 GDSC1 4.918 6.5598 3.6523 3.4723
HT115 GDSC1 5.0974 6.5166 3.7836 2.1248
HT-29 GDSC1 5.1132 6.9583 3.5903 3.4546
RKO GDSC1 5.1255 6.8476 3.6494 3.0029
SNU-175 GDSC1 5.1311 7.711 3.2451 5.9624
SNU-1040 GDSC1 5.159 7.312 3.4537 4.3414
GP5d GDSC1 5.2431 7.0842 3.6121 3.0108
T84 GDSC1 5.2449 7.1522 3.5819 3.2187
HCT 15 GDSC1 5.2577 6.8901 3.7084 2.3199
SNU-C1 GDSC1 5.2833 7.1673 3.5982 3.0228
CL-11 GDSC1 5.4741 7.4614 3.5766 2.7881
SNU-C5 GDSC1 5.6373 7.7543 3.5383 2.7377
SW626 GDSC1 5.8036 7.8547 3.584 2.1707
LoVo GDSC1 5.8466 7.8638 3.6023 1.9957
SNU-81 GDSC1 6.0635 8.4923 3.4469 2.5961
SW948 GDSC1 6.073 7.3974 3.8878 0.4016
RCM-1 [Human ESC] GDSC1 6.1967 7.4154 3.9281 0.2322
HCC2998 GDSC1 6.2516 8.0755 3.7069 0.9683
LS123 GDSC1 6.4083 7.8877 3.8402 0.3713
SW1116 GDSC1 6.5418 7.925 3.8764 0.2281
SW837 GDSC1 6.5753 8.7947 3.5689 1.2879
SW1417 GDSC1 6.6157 8.3681 3.7469 0.5467
SW620 GDSC1 6.8726 8.3754 3.8397 0.2028
CW-2 GDSC1 7.1734 8.9679 3.7435 0.3063
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 5.8412 8.6234 3.2666 4.1593
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-475 GDSC1 3.1184 3.692 3.1132 15.0767
JHH-6 GDSC1 3.2536 4.3089 3.1596 13.9706
Hep 3B2.1-7 GDSC1 3.8273 4.3623 3.7706 6.5581
SNU-449 GDSC1 3.8991 4.663 3.7373 6.4126
Huh-7 GDSC1 4.0069 6.2414 3.0885 10.925
SNU-423 GDSC1 4.1864 6.4446 3.1456 9.7735
JHH-4 GDSC1 4.2377 5.102 3.8596 3.9629
JHH-7 GDSC1 4.3145 5.3607 3.7963 4.1723
Hep-G2/C3A GDSC1 4.3533 5.2493 3.8841 3.3409
JHH-2 GDSC1 5.106 6.8167 3.6516 3.0305
SNU-387 GDSC1 5.1149 7.2557 3.4516 4.4661
SK-HEP-1 GDSC1 6.0721 7.4426 3.871 0.4577
JHH-1 GDSC1 6.1954 7.4725 3.9076 0.2837
HLE GDSC1 6.3845 8.1849 3.7215 0.7948
HuH-1 GDSC1 6.5574 8.0622 3.8342 0.3212
SNU-398 GDSC1 6.5734 8.3646 3.7315 0.6242
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H847 GDSC1 2.9658 3.7639 2.9489 17.0583
KNS-62 GDSC1 3.0018 4.0303 2.9491 16.8407
NCI-H1436 GDSC1 3.0637 3.9228 3.0336 15.9192
NCI-H650 GDSC1 3.1087 3.8596 3.0896 15.2869
HCC78 GDSC1 3.1369 4.0746 3.0868 15.1351
NCI-H1092 GDSC1 3.1686 5.1051 2.7879 17.0462
NCI-H196 GDSC1 3.2101 3.888 3.1938 14.0013
NCI-H2795 GDSC1 3.266 4.2229 3.195 13.6605
NCI-H187 GDSC1 3.2681 4.8696 2.9867 15.1
NCI-H1781 GDSC1 3.2755 4.1328 3.2254 13.4034
NCI-H2030 GDSC1 3.3088 4.0555 3.2759 12.8748
LK-2 GDSC1 3.3815 4.5348 3.2304 12.7674
NCI-H810 GDSC1 3.4153 4.4481 3.2954 12.1295
NCI-H2731 GDSC1 3.4337 5.2556 3.001 14.1546
NCI-H1975 GDSC1 3.4659 4.389 3.3686 11.3434
EPLC-272H GDSC1 3.4679 4.3619 3.3787 11.2632
NCI-H292 GDSC1 3.5566 4.2321 3.5094 9.8735
NCI-H661 GDSC1 3.5638 4.3414 3.4891 9.9679
COR-L303 GDSC1 3.5744 5.7665 2.9105 14.1626
Lu-134-A GDSC1 3.6074 4.82 3.3662 10.6023
NCI-H1581 GDSC1 3.619 4.3567 3.545 9.2742
NCI-H1563 GDSC1 3.639 4.2906 3.585 8.8893
LOU-NH91 GDSC1 3.6455 4.2605 3.5995 8.7548
NCI-H727 GDSC1 3.679 4.3947 3.5991 8.5665
HCC15 GDSC1 3.6819 4.3822 3.6061 8.5021
EMC-BAC-2 GDSC1 3.7076 4.4851 3.6008 8.3966
COR-L105 GDSC1 3.7708 4.5176 3.6576 7.6554
ChaGo-K-1 GDSC1 3.7826 4.4462 3.6953 7.3263
HCC44 GDSC1 3.7866 4.489 3.6849 7.3775
NCI-H322M GDSC1 3.7895 4.9577 3.4967 8.7342
NCI-H460 GDSC1 3.8094 4.1465 3.7989 6.4734
NCI-H1573 GDSC1 3.8494 4.43 3.7732 6.4171
NCI-H1651 GDSC1 3.8558 4.4996 3.7557 6.5053
NCI-H647 GDSC1 3.8634 4.5957 3.7271 6.6696
HARA [Human squamous cell lung carcinoma] GDSC1 3.8759 4.5028 3.7761 6.2537
NCI-H2291 GDSC1 3.879 4.998 3.5689 7.7652
RERF-LC-MS GDSC1 3.8971 4.604 3.7594 6.2623
HCC827 GDSC1 3.9158 4.4948 3.8219 5.7155
NCI-H1915 GDSC1 3.9244 4.4877 3.8337 5.5859
SW1271 GDSC1 3.9244 5.3738 3.4366 8.5685
NCI-H2595 GDSC1 3.9412 4.6452 3.7887 5.8247
DMS 53 GDSC1 3.9433 4.687 3.7731 5.9293
NCI-H1355 GDSC1 3.945 4.788 3.7306 6.2363
COR-L23 GDSC1 3.9524 4.6909 3.7808 5.8273
SK-MES-1 GDSC1 3.9599 4.6597 3.802 5.6338
NCI-H3255 GDSC1 3.9802 5.0911 3.6254 6.8703
NCI-H1793 GDSC1 4.0591 4.7816 3.8481 4.8119
LCLC-103H GDSC1 4.0602 4.8558 3.8146 5.0619
NCI-H596 GDSC1 4.1035 5.1868 3.6962 5.7873
NCI-H2369 GDSC1 4.1487 5.083 3.7888 4.8771
NCI-H2722 GDSC1 4.199 5.9837 3.3865 7.8341
NCI-H1944 GDSC1 4.2408 6.3339 3.2475 8.7691
NCI-H838 GDSC1 4.2596 5.0305 3.9145 3.4464
NCI-H2170 GDSC1 4.2637 5.375 3.7461 4.7571
NCI-H2066 GDSC1 4.2872 5.6323 3.6376 5.5243
DMS 273 GDSC1 4.304 5.7139 3.6109 5.6725
NCI-H526 GDSC1 4.3501 6.2338 3.3894 7.2525
NCI-H2122 GDSC1 4.3595 5.4142 3.8067 3.9294
RERF-LC-Sq1 GDSC1 4.3663 6.2336 3.4028 7.0889
NCI-H2029 GDSC1 4.3906 6.5416 3.2688 8.057
NCI-H1650 GDSC1 4.4183 6.7013 3.2116 8.409
NCI-H226 GDSC1 4.47 5.6693 3.7673 3.8661
NCI-H146 GDSC1 4.4917 6.2067 3.517 5.7592
NCI-H290 GDSC1 4.5398 5.8124 3.7495 3.7841
Calu-6 GDSC1 4.5523 5.806 3.762 3.6482
CAL-12T GDSC1 4.5925 6.2414 3.5773 4.9622
NCI-H720 GDSC1 4.6783 12.4585 0.5467 24.5145
A-549 GDSC1 4.6907 6.3669 3.5881 4.5808
NCI-H520 GDSC1 4.7234 6.7401 3.4289 5.7146
NCI-H1341 GDSC1 4.7308 6.4422 3.5802 4.5245
NCI-H841 GDSC1 4.7707 6.7246 3.471 5.2495
SW1573 GDSC1 4.8134 6.4368 3.6408 3.8313
NCI-H441 GDSC1 4.9251 6.7251 3.5782 4.0066
NCI-H345 GDSC1 4.9578 8.632 2.6711 10.7708
NCI-H1703 GDSC1 5.0033 6.6708 3.6552 3.2421
NCI-H209 GDSC1 5.0126 6.95 3.5293 4.1473
IST-SL1 GDSC1 5.0581 7.0066 3.5323 4.0109
SHP-77 GDSC1 5.1606 7.1817 3.516 3.8824
NCI-H2869 GDSC1 5.1917 7.2961 3.4822 4.0547
NCI-H2135 GDSC1 5.3341 7.1555 3.6333 2.6781
NCI-H2081 GDSC1 5.3647 8.9975 2.7858 8.7324
NCI-H1155 GDSC1 5.3812 6.93 3.759 1.7702
Lu-135 GDSC1 5.4459 10.3281 2.1962 12.6526
SBC-5 GDSC1 5.4529 6.3746 4.0173 0.3423
NCI-H2810 GDSC1 5.4779 7.8976 3.3809 4.1286
ABC-1 GDSC1 5.4821 8.0473 3.3145 4.5901
EBC-1 GDSC1 5.6218 7.6015 3.5968 2.3885
BEN GDSC1 5.7088 6.672 4.0089 0.2269
NCI-H1838 GDSC1 5.712 7.4181 3.7215 1.4983
NCI-H1299 GDSC1 5.728 7.6495 3.6323 1.9956
Lu-165 GDSC1 5.794 7.9172 3.5522 2.3809
NCI-H2444 GDSC1 5.7974 7.6717 3.6582 1.7405
PaCa-3 GDSC1 5.7998 8.0878 3.4813 2.8182
COR-L88 GDSC1 5.8133 8.1494 3.4617 2.9206
NCI-H2228 GDSC1 5.831 9.5552 2.8306 7.2102
NCI-H2141 GDSC1 5.8604 8.2779 3.4311 3.034
NCI-H2803 GDSC1 5.9222 8.1044 3.539 2.2591
NCI-H64 GDSC1 5.9437 8.8239 3.2357 4.1644
NCI-H2171 GDSC1 5.9775 7.9054 3.6497 1.5474
Lu-139 GDSC1 6.0094 8.8704 3.2524 3.9274
HCC33 GDSC1 6.0116 7.7621 3.7233 1.1281
NCI-H2196 GDSC1 6.0279 7.6786 3.7634 0.9225
PC-14 GDSC1 6.0752 7.9375 3.6825 1.2606
NCI-H2373 GDSC1 6.0878 8.3137 3.5348 2.041
NCI-H2347 GDSC1 6.1277 13.4187 1.1765 16.8757
NCI-H1694 GDSC1 6.1693 7.8663 3.7521 0.8448
NCI-H3122 GDSC1 6.1918 8.8825 3.3468 3.004
COLO 668 GDSC1 6.2091 8.2639 3.6135 1.4587
NCI-H1435 GDSC1 6.253 8.0145 3.731 0.8629
LB647-SCLC GDSC1 6.2631 8.0305 3.7291 0.8621
LCLC-97TM1 GDSC1 6.3225 8.6308 3.5183 1.8223
NCI-H2804 GDSC1 6.3289 8.8266 3.4407 2.2422
NCI-H82 GDSC1 6.3778 7.8456 3.8437 0.3761
NCI-H23 GDSC1 6.3911 8.3751 3.6515 1.0869
CPC-N GDSC1 6.4027 9.519 3.1841 3.6638
NCI-H1688 GDSC1 6.4312 8.4798 3.6283 1.1541
NCI-H522 GDSC1 6.4432 8.4618 3.6406 1.0876
SBC-3 GDSC1 6.4628 8.3436 3.6942 0.8432
RERF-LC-KJ GDSC1 6.5061 7.9651 3.8494 0.3037
Ms-1 GDSC1 6.5146 8.3308 3.7204 0.7034
NCI-H2591 GDSC1 6.5291 8.9883 3.4709 1.8213
NCI-H1105 GDSC1 6.5451 8.2691 3.7553 0.5606
Lu-65 GDSC1 6.5458 8.5766 3.6405 0.9973
NCI-H2009 GDSC1 6.5612 8.5683 3.6502 0.9436
NCI-H1792 GDSC1 6.5622 8.2861 3.7558 0.5487
NCI-H1770 GDSC1 6.5673 7.7609 3.9411 0.108
SK-LU-1 GDSC1 6.5906 8.6033 3.6493 0.9237
NCI-H1666 GDSC1 6.5941 8.8586 3.5522 1.3472
COR-L311 GDSC1 6.6033 8.5537 3.6733 0.8181
NCI-H2087 GDSC1 6.6064 8.7039 3.6176 1.0427
SBC-1 GDSC1 6.6086 8.1556 3.8203 0.3356
LC-2/ad GDSC1 6.6125 8.5565 3.676 0.8008
NCI-H510A GDSC1 6.6437 8.6005 3.6724 0.792
COR-L321 GDSC1 6.6518 8.0832 3.8613 0.2247
NCI-H69 GDSC1 6.6776 8.8521 3.5912 1.0943
Calu-3 GDSC1 6.68 8.3327 3.7844 0.4003
Lu-99A GDSC1 6.6812 8.8602 3.5896 1.098
EKVX GDSC1 6.6829 9.3217 3.4082 1.9649
IA-LM GDSC1 6.6908 8.3275 3.7903 0.3793
NCI-H211 GDSC1 6.6972 8.8049 3.6175 0.9675
NCI-H2110 GDSC1 6.7015 12.0072 2.2349 9.1671
NCI-H1304 GDSC1 6.7076 8.1711 3.8511 0.2285
HOP-62 GDSC1 6.7147 8.4465 3.7569 0.4622
DMS 114 GDSC1 6.7256 8.772 3.6417 0.8496
NCI-H2461 GDSC1 6.7282 8.524 3.7342 0.5242
NCI-H446 GDSC1 6.7378 8.3749 3.7911 0.3569
NCI-H1623 GDSC1 6.7532 8.8321 3.6306 0.8724
NCI-H1755 GDSC1 6.7663 8.4568 3.7728 0.393
NCI-H1836 GDSC1 6.773 8.2878 3.8343 0.2428
NCI-H524 GDSC1 6.7774 8.444 3.7814 0.3651
NCI-H513 GDSC1 6.78 8.6686 3.7019 0.5985
NCI-H2818 GDSC1 6.7844 8.4134 3.7948 0.3287
NCI-H2342 GDSC1 6.8118 8.5897 3.7426 0.4557
NCI-H358 GDSC1 6.851 9.1429 3.5538 1.1052
NCI-H2172 GDSC1 6.8576 8.3143 3.8552 0.1789
NCI-H1869 GDSC1 6.861 8.8903 3.6527 0.7159
NCI-H1734 GDSC1 6.8994 8.8248 3.6917 0.5635
NCI-H1876 GDSC1 6.9135 8.5582 3.7914 0.2889
NCI-H1993 GDSC1 6.9366 8.8377 3.7014 0.5143
NCI-H1048 GDSC1 6.9388 8.7105 3.7475 0.3852
UMC-11 GDSC1 6.9612 8.7675 3.7357 0.4063
IST-SL2 GDSC1 6.967 9.4605 3.4814 1.3151
NCI-H2085 GDSC1 6.976 8.8176 3.7235 0.4325
LXF 289 GDSC1 7.0196 8.7069 3.7783 0.2819
NCI-H1648 GDSC1 7.0615 9.1529 3.6358 0.6507
NCI-H1568 GDSC1 7.1524 8.8863 3.7641 0.2694
NCI-H2405 GDSC1 7.2076 9.0923 3.7127 0.3645
NCI-H2023 GDSC1 7.2355 8.652 3.8716 0.0873
A-427 GDSC1 7.3587 9.5987 3.5897 0.6318
NCI-H1437 GDSC1 7.4502 9.2023 3.7613 0.1953
EMC-BAC-1 GDSC1 7.7268 10.4549 3.422 0.9673
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 6.5876 8.6491 3.6306 1.0037
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-410 GDSC1 3.0618 4.0947 3.0015 16.1404
KYSE-450 GDSC1 3.0664 3.9328 3.0351 15.8935
TE-4 GDSC1 3.1968 4.2041 3.1241 14.5367
KYSE-520 GDSC1 3.3847 5.3916 2.891 15.2079
KYSE-150 GDSC1 3.7846 4.5114 3.6747 7.4597
T.T GDSC1 3.9311 4.924 3.655 6.8703
TE-5 GDSC1 3.9927 4.8381 3.7561 5.818
COLO 680N GDSC1 4.1159 8.8803 1.8688 19.3715
TE-10 GDSC1 4.1894 5.451 3.6435 5.851
OE21 GDSC1 4.4393 6.7305 3.214 8.317
TE-9 GDSC1 4.4953 5.7283 3.7575 3.8622
KYSE-70 GDSC1 4.7188 6.2535 3.6636 3.9188
TE-8 GDSC1 4.7195 6.8122 3.3906 6.0226
TE-15 GDSC1 4.78 8.0819 2.8087 10.3078
TE-1 GDSC1 4.8074 6.3982 3.6552 3.7381
OE33 GDSC1 5.3173 8.1366 3.1667 6.0594
KYSE-510 GDSC1 5.6133 7.7466 3.5284 2.8468
TE-11 GDSC1 5.7328 7.7096 3.6091 2.1287
OE19 GDSC1 6.4946 7.7128 3.9322 0.1363
KYSE-270 GDSC1 6.7788 9.0161 3.5715 1.0914
KYSE-180 GDSC1 6.8863 8.4597 3.8157 0.2458
EC-GI-10 GDSC1 6.9166 14.4847 1.2064 14.6684
KYSE-140 GDSC1 7.0662 10.1283 3.2619 2.2681
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Kuramochi GDSC1 3.3163 4.3088 3.228 13.149
OVCAR-4 GDSC1 3.7756 4.4657 3.681 7.4646
OC 314 GDSC1 3.787 4.1456 3.7752 6.7619
ES-2 GDSC1 3.8071 4.2537 3.7771 6.6298
EFO-27 GDSC1 3.811 4.3914 3.7439 6.833
EFO-21 GDSC1 3.8688 4.3388 3.8227 5.9681
FU-OV-1 GDSC1 3.9261 4.7305 3.7366 6.284
OVCAR-5 GDSC1 3.9559 4.6572 3.799 5.6755
IGROV-1 GDSC1 3.9717 4.9269 3.6942 6.3846
SK-OV-3 GDSC1 4.0045 4.6544 3.8504 5.055
Caov-3 GDSC1 4.0062 4.6392 3.8587 4.9853
JHOS-4 GDSC1 4.0416 4.8239 3.8112 5.1728
OV-90 GDSC1 4.0873 5.5139 3.5207 7.2234
OVISE GDSC1 4.2799 5.0077 3.9434 3.1409
A2780 GDSC1 4.3806 13.5732 -0.2549 28.7706
Caov-4 GDSC1 4.4666 6.1677 3.5167 5.8457
DOV13 GDSC1 4.5369 5.8311 3.7382 3.8813
OVCAR-3 GDSC1 4.5877 5.8967 3.7436 3.6842
OVKATE GDSC1 4.7272 6.3033 3.6453 4.0354
OVCAR-8 GDSC1 4.7598 6.015 3.8067 2.7245
TOV-21G GDSC1 4.975 6.5577 3.6902 3.0542
TYK-nu GDSC1 5.021 6.8632 3.576 3.7804
OV56 GDSC1 5.0989 7.1035 3.5131 4.0522
OVK18 GDSC1 5.9899 7.9148 3.6518 1.5205
JHOS-2 GDSC1 6.3052 7.8107 3.8283 0.4612
OAW42 GDSC1 6.4095 7.3734 4.016 0.0468
OAW28 GDSC1 6.542 9.3536 3.3268 2.5934
RMG-I GDSC1 6.6027 8.5738 3.6655 0.8493
TOV-112D GDSC1 6.9968 8.904 3.7006 0.4867
OVTOKO GDSC1 7.4697 9.5254 3.6574 0.3975
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuP-T4 GDSC1 3.8893 4.5876 3.7578 6.3143
YAPC GDSC1 3.8944 4.3001 3.8611 5.5613
Panc 10.05 GDSC1 4.1395 5.0355 3.8036 4.8002
Hs 766T GDSC1 4.2614 5.1639 3.8495 3.9507
SUIT-2 GDSC1 4.5117 5.5231 3.8712 2.9237
Capan-1 GDSC1 4.5399 6.1975 3.559 5.2719
PaTu 8988t GDSC1 4.5562 5.5151 3.9075 2.5116
Panc 02.03 GDSC1 4.5654 5.8097 3.7699 3.5471
AsPC-1 GDSC1 4.7911 7.859 2.9276 9.37
MZ-PC-1 GDSC1 4.8619 7.1527 3.3274 6.0868
KP-1N GDSC1 4.9268 6.5393 3.6678 3.3357
PL4 GDSC1 6.1058 8.2285 3.5789 1.7688
PaTu 8902 GDSC1 6.2297 7.4675 3.922 0.2343
Panc 08.13 GDSC1 6.2385 8.0511 3.7107 0.9634
SU.86.86 GDSC1 6.3292 7.6836 3.8829 0.2913
Capan-2 GDSC1 6.4272 8.7255 3.5293 1.6389
HuP-T3 GDSC1 6.4647 8.2971 3.7125 0.7692
CFPAC-1 GDSC1 6.5028 8.1762 3.7726 0.5283
Panc 04.03 GDSC1 6.6126 8.2985 3.7709 0.4728
MIA PaCa-2 GDSC1 6.6227 7.837 3.9346 0.1066
HPAC GDSC1 6.6824 8.0154 3.8952 0.1534
KP-4 GDSC1 6.6909 8.1549 3.8507 0.2346
QGP-1 GDSC1 6.6911 8.3757 3.7732 0.4264
BxPC-3 GDSC1 6.7135 8.7534 3.6437 0.8507
Panc 03.27 GDSC1 6.7737 8.2123 3.8604 0.1912
PSN1 GDSC1 6.8704 8.494 3.7981 0.289
HPAF-II GDSC1 6.9958 9.0998 3.6293 0.7118
DAN-G GDSC1 7.0431 8.4504 3.8734 0.1135
SW1990 GDSC1 7.0659 9.4037 3.5448 0.9717
KP-3 GDSC1 7.3286 9.1045 3.7519 0.242
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1 3.8877 5.2388 3.4655 8.5109
MPP 89 GDSC1 4.1972 5.3652 3.6931 5.4305
NCI-H2452 GDSC1 4.8064 7.0134 3.3555 6.0336
MSTO-211H GDSC1 6.3201 8.5515 3.5494 1.6605
IST-Mes1 GDSC1 6.6965 8.7727 3.6294 0.9201
NCI-H2052 GDSC1 7.2298 15.8779 0.7508 16.2246
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1 3.6602 4.9016 3.3876 10.179
DU145 GDSC1 3.8302 4.439 3.7493 6.6889
22Rv1 GDSC1 6.2653 8.119 3.696 1.0042
PC-3 GDSC1 6.3324 9.1234 3.3173 2.9603
LNCaP clone FGC GDSC1 6.9764 8.7965 3.7311 0.4119
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 3.2666 4.0354 3.2339 13.4013
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-144 GDSC1 2.8003 3.2358 2.8002 19.0211
COLO 829 GDSC1 2.8057 3.3965 2.8038 18.9643
A-431 GDSC1 2.8067 3.599 2.796 19.0077
WM278 GDSC1 2.8565 3.6061 2.8474 18.375
Mel Ho GDSC1 2.8638 3.3172 2.8634 18.2294
Hs 938.T GDSC1 2.8751 3.2786 2.875 18.0863
SK-MEL-30 GDSC1 2.9218 3.4405 2.9205 17.5096
COLO 679 GDSC1 2.9514 3.5675 2.9472 17.1581
IPC-298 GDSC1 2.9946 3.4248 2.9942 16.594
LB373-MEL-D GDSC1 3.0625 4.6586 2.8427 17.2193
WM793 GDSC1 3.0808 3.6788 3.0752 15.5492
CP50-MEL-B GDSC1 3.1178 4.0539 3.0701 15.3582
WM115 GDSC1 3.1882 3.8404 3.1755 14.252
SK-MEL-2 GDSC1 3.2804 4.5177 3.1263 14.0481
COLO 800 GDSC1 3.3105 4.1875 3.2517 13.0243
IGR-37 GDSC1 3.422 4.2901 3.3484 11.7306
MZ-MEL-7 GDSC1 3.5396 4.8819 3.2696 11.651
Mel JuSo GDSC1 3.5821 4.2892 3.5233 9.6323
SK-MEL-24 GDSC1 3.6396 4.3099 3.5805 8.9167
M14 GDSC1 3.6417 4.4521 3.5403 9.1803
A101D GDSC1 3.699 4.1168 3.6852 7.8747
A-388 GDSC1 3.7071 5.7172 3.0632 12.3999
IGR-1 GDSC1 3.7518 4.4656 3.6554 7.7737
LOX-IMVI GDSC1 3.8162 4.3417 3.7645 6.6626
IST-MEL1 GDSC1 3.8172 4.4562 3.7294 6.8989
G-361 GDSC1 3.8195 4.2842 3.7835 6.5149
MeWo GDSC1 3.878 4.3589 3.8269 5.8866
SK-MEL-28 GDSC1 3.9141 4.1924 3.9044 5.1594
CHL-1 GDSC1 3.9229 4.6667 3.7605 6.1235
SK-MEL-3 GDSC1 3.9257 4.4053 3.8642 5.3642
CP66-MEL GDSC1 3.9452 4.6795 3.7783 5.8815
HMV-II GDSC1 3.9505 4.8634 3.7022 6.4235
WT2-iPS GDSC1 4.0364 5.1465 3.6528 6.4112
GAK GDSC1 4.041 4.6221 3.902 4.4932
MMAc-SF GDSC1 4.0864 5.256 3.6465 6.2458
451Lu GDSC1 4.1127 4.9282 3.8306 4.7052
SK-MEL-1 GDSC1 4.1901 5.8118 3.4644 7.2556
RPMI-7951 GDSC1 4.1925 5.0391 3.8506 4.2143
WM1552C GDSC1 4.2056 6.628 3.0706 10.2875
A2058 GDSC1 4.3727 5.167 3.9409 2.8263
A-375 GDSC1 4.5083 5.742 3.7606 3.7961
RVH-421 GDSC1 4.5628 6.6362 3.3589 6.7647
LB2518-MEL GDSC1 4.639 6.6369 3.4169 6.0673
COLO 783 GDSC1 4.7133 6.2742 3.6497 4.0413
G-mel GDSC1 4.7454 6.3181 3.651 3.9407
UACC-62 GDSC1 4.7762 6.5474 3.5613 4.5398
SK-MEL-5 GDSC1 6.1649 7.7015 3.8126 0.6052
MZ-MEL-2 GDSC1 6.4456 8.4842 3.633 1.1196
SH-4 GDSC1 6.6367 8.6211 3.6618 0.8381
UACC-257 GDSC1 6.7039 8.3031 3.8038 0.3384
DJM-1 GDSC1 7.3108 9.323 3.6698 0.4296
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 4.5147 6.399 3.4394 6.292
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh41 GDSC1 2.8266 3.5137 2.8214 18.724
Hs 633.T GDSC1 2.8512 3.3598 2.8504 18.3894
G-401 GDSC1 2.8815 3.6822 2.8678 18.0915
Rh18 GDSC1 3.0827 3.651 3.0785 15.5168
GCT GDSC1 3.3627 4.1589 3.3147 12.3
TE 441.T GDSC1 3.5658 4.6456 3.3903 10.6459
G-402 GDSC1 3.7708 5.5873 3.1868 11.1697
SW684 GDSC1 3.8133 4.1969 3.7954 6.4726
SW982 GDSC1 3.828 5.0585 3.4902 8.5987
RKN GDSC1 3.8482 4.2945 3.8122 6.1564
MES-SA GDSC1 6.0457 7.2838 3.9183 0.323
Rh30 GDSC1 6.1978 8.322 3.5848 1.6217
SW872 GDSC1 6.3549 8.2278 3.6927 0.9385
HT-1080 GDSC1 6.4239 7.7244 3.9032 0.2092
KYM-1 GDSC1 6.6416 8.0706 3.862 0.2265
VA-ES-BJ GDSC1 6.6787 8.3623 3.7733 0.4321
MFH-ino GDSC1 6.7522 8.4511 3.7695 0.4083
SK-LMS-1 GDSC1 6.8658 8.4569 3.8093 0.2658
EW-8 GDSC1 6.8868 8.4692 3.8126 0.2521
SK-UT-1 GDSC1 7.1841 8.8847 3.7759 0.2367
A-204 GDSC1 7.4328 9.6104 3.6137 0.5253
RD GDSC1 7.769 17.0001 0.574 15.8225
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCH GDSC1 2.7056 3.3273 2.7037 20.2161
HGC-27 GDSC1 2.7893 3.7868 2.7593 19.3483
MKN1 GDSC1 2.8682 3.3459 2.8677 18.1749
RERF-GC-1B GDSC1 2.8977 3.8972 2.8596 18.0456
MKN7 GDSC1 2.9074 3.7486 2.8888 17.7991
MKN45 GDSC1 3.0392 3.4792 3.0385 16.0387
NCI-N87 GDSC1 3.4625 4.7066 3.2567 12.1449
Fu97 GDSC1 3.5381 4.2469 3.4858 10.1382
OCUM-1 GDSC1 3.7208 4.8262 3.4826 9.1773
IM95 GDSC1 3.7794 4.4072 3.7045 7.2804
HSC-39 GDSC1 3.8377 4.5739 3.7083 6.9394
SNU-5 GDSC1 4.1052 4.8678 3.8525 4.5697
23132/87 GDSC1 4.2808 5.3325 3.782 4.4098
ECC10 GDSC1 4.4453 6.2279 3.4697 6.287
NUGC-3 GDSC1 4.5868 8.3724 2.513 13.1588
NUGC-4 GDSC1 5.0528 6.8588 3.5986 3.5372
Hs 746.T GDSC1 5.2582 8.5155 2.9448 7.8575
SNU-1 GDSC1 5.4873 7.8116 3.4261 3.7917
SNU-16 GDSC1 6.3066 7.4779 3.946 0.1592
AGS GDSC1 6.5824 8.0412 3.8508 0.2712
GCIY GDSC1 6.6179 8.2042 3.8067 0.3676
RF-48 GDSC1 6.7597 8.1895 3.8632 0.1898
KATO III GDSC1 6.8276 8.5819 3.7514 0.4235
MKN28 GDSC1 6.9598 8.8183 3.7172 0.4573
TGBC11TKB GDSC1 7.4147 9.1172 3.7777 0.1773
SNG-M GDSC1 5.9465 8.1587 3.5285 2.2849
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CGTH-W-1 GDSC1 2.8407 3.2561 2.8406 18.5157
KMH-2 GDSC1 3.0519 3.8153 3.0344 15.9858
ML-1 [Human leukemia] GDSC1 4.1604 5.1153 3.7837 4.868
BHT-101 GDSC1 4.5471 5.9996 3.6626 4.4395
ASH-3 GDSC1 4.5539 5.7656 3.7831 3.4797
WRO GDSC1 5.0235 7.5569 3.2453 6.2542
TT2609-C02 GDSC1 5.2412 7.5264 3.4057 4.4939
IHH-4 GDSC1 5.5292 7.2935 3.6807 2.0151
CAL-62 GDSC1 6.1894 7.5199 3.8885 0.3388
B-CPAP GDSC1 6.283 7.7433 3.8441 0.4236
K5 GDSC1 6.4575 8.5818 3.6001 1.2591
8505C GDSC1 6.4614 8.5107 3.6296 1.1201
HTC-C3 GDSC1 6.5252 8.4162 3.6927 0.8011
8305C GDSC1 6.5483 8.4084 3.7052 0.7365
TT GDSC1 6.7527 8.2901 3.8262 0.267
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-38 GDSC1 2.7604 3.3843 2.758 19.5341
BB49-HNC GDSC1 2.768 3.5065 2.7615 19.4652
PE/CA-PJ15 GDSC1 2.777 3.3164 2.7761 19.3173
SAS GDSC1 2.7909 3.4872 2.7859 19.169
SCC-9 GDSC1 2.8203 3.3779 2.8189 18.7793
HO-1-u-1 GDSC1 2.8409 3.5298 2.8354 18.5474
OSC-20 GDSC1 2.9327 3.691 2.9206 17.4413
JHU-022 GDSC1 2.9844 3.7221 2.9721 16.7966
BHY GDSC1 3.0343 3.8294 3.0143 16.2223
DOK GDSC1 3.0933 4.0289 3.0482 15.6471
NCI-H3118 GDSC1 3.1541 4.1287 3.0945 14.983
BICR 78 GDSC1 3.2692 4.1426 3.2165 13.4993
BB30-HNC GDSC1 3.3057 4.2136 3.2405 13.1261
PCI-04B GDSC1 3.3258 4.2828 3.2453 12.9779
BICR 22 GDSC1 3.409 4.6437 3.2224 12.674
PCI-15A GDSC1 3.4245 4.3846 3.3248 11.8763
SKN-3 GDSC1 3.4653 4.4289 3.3558 11.4348
LB771-HNC GDSC1 3.6312 4.4597 3.5265 9.3335
HSC-2 GDSC1 3.6623 4.1259 3.6446 8.3582
HO-1-N-1 GDSC1 3.7054 4.5167 3.5873 8.5035
KON GDSC1 3.7689 4.2893 3.727 7.1862
HSC-3 GDSC1 3.7942 4.318 3.747 6.9062
JHU-011 GDSC1 3.7983 4.5747 3.6659 7.4497
Ca9-22 GDSC1 3.8135 4.5027 3.709 7.0631
HSC-4 GDSC1 3.8391 4.2452 3.8138 6.1984
Detroit 562 GDSC1 3.8398 4.4185 3.7666 6.5159
CAL-27 GDSC1 3.852 4.2714 3.8219 6.0694
SCC-25 GDSC1 3.8698 4.7495 3.6701 7.0541
CAL-33 GDSC1 4.2015 5.1799 3.7889 4.6614
PCI-06A GDSC1 4.2916 5.5306 3.6921 5.0778
FaDu GDSC1 4.3861 5.3125 3.879 3.2677
OSC-19 GDSC1 4.4121 6.5482 3.283 7.8703
BICR 31 GDSC1 4.6387 5.9833 3.7381 3.576
BICR 10 GDSC1 6.8825 8.7431 3.7146 0.5024
PCI-30 GDSC1 6.8901 8.9746 3.6332 0.7659
SCC-15 GDSC1 7.0418 8.9568 3.6988 0.4703
KOSC-2 GDSC1 7.5854 9.5747 3.6822 0.3036
SAT [Human HNSCC] GDSC1 7.7647 9.9655 3.6117 0.3961
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-112 GDSC1 2.8183 3.255 2.8181 18.7963
SW1710 GDSC1 3.6267 4.5487 3.491 9.6066
CAL-29 GDSC1 3.6548 4.3176 3.5951 8.7309
SW780 GDSC1 3.6816 4.3287 3.6212 8.4008
TCCSUP GDSC1 3.683 4.525 3.5602 8.8153
UM-UC-3 GDSC1 3.7374 4.5118 3.6237 8.0741
T24 GDSC1 3.7858 4.4477 3.6982 7.2892
J82 GDSC1 3.8705 4.4263 3.7973 6.1335
HT-1197 GDSC1 4.0751 4.7026 3.9005 4.3405
HT-1376 GDSC1 4.3639 5.6185 3.7083 4.6893
639V GDSC1 5.07 7.2237 3.4371 4.6871
5637 GDSC1 5.1216 7.528 3.3264 5.3793
647V GDSC1 5.4719 6.9228 3.8087 1.333
KU-19-19 GDSC1 5.9701 6.9777 3.9978 0.1554
BFTC-905 GDSC1 6.1538 7.4174 3.9115 0.2914
RT-4 GDSC1 6.8439 8.664 3.7282 0.4817
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-IT GDSC1 2.5833 3.4031 2.5763 21.777
TC-YIK GDSC1 3.0566 4.7876 2.7907 17.6159
KGN GDSC1 3.5366 4.5153 3.4052 10.698
HT-3 GDSC1 3.6515 4.7666 3.4344 9.8811
ACC-OV7 GDSC1 3.7294 4.6275 3.5721 8.4838
Ca Ski GDSC1 3.8266 4.9104 3.5555 8.1164
PA-1 GDSC1 3.8633 4.614 3.7197 6.7241
DoTc2 4510 GDSC1 4.0184 4.8249 3.7877 5.4593
HEY GDSC1 4.0566 5.21 3.6412 6.414
OMC-1 [Human cervical carcinoma] GDSC1 4.091 5.1214 3.7166 5.6818
SiHa GDSC1 4.1137 4.6858 3.9467 3.8112
SW756 GDSC1 4.1244 4.9106 3.8503 4.5024
PWR-1E GDSC1 4.301 5.3876 3.7715 4.4176
SiSo GDSC1 4.3792 8.3598 2.3505 15.0782
DSH1 GDSC1 4.3928 6.2243 3.4291 6.7883
SKG-IIIa GDSC1 4.4015 6.3832 3.3568 7.3271
SKN GDSC1 4.5822 6.599 3.3924 6.4391
MS751 GDSC1 4.6709 6.2117 3.6498 4.1631
OVMIU GDSC1 5.1001 7.2817 3.4295 4.667
OVCA420 GDSC1 5.2138 7.2708 3.5079 3.8164
SW962 GDSC1 5.2584 7.5988 3.3827 4.6202
HeLa GDSC1 5.5435 6.9047 3.8508 1.0092
BPH-1 GDSC1 5.7 9.6241 2.7127 8.3659
UWB1.289 GDSC1 5.7752 8.4126 3.3232 3.9074
NT2-D1 GDSC1 5.832 7.4655 3.7594 1.1454
SW954 GDSC1 5.8419 8.5898 3.2821 4.0527
JHOS-3 GDSC1 5.9918 8.366 3.4635 2.6088
CAL-39 GDSC1 6.0481 8.3438 3.5021 2.2888
JEG-3 GDSC1 6.0647 8.1694 3.5833 1.7986
NEC8 GDSC1 6.1669 7.8379 3.7619 0.8053
C-4-I GDSC1 6.1786 7.7908 3.7847 0.7026
LB831-BLC GDSC1 6.1941 8.7301 3.4132 2.5973
OVCA433 GDSC1 6.2893 8.927 3.3786 2.6595
HEC-1 GDSC1 6.4313 7.7767 3.8878 0.2403
JAR GDSC1 6.5515 8.2026 3.782 0.4713
PEO1 GDSC1 6.8957 9.1057 3.5866 0.9369
OV17R GDSC1 7.1384 9.2904 3.6158 0.6712
C-33 A GDSC1 7.2913 9.0612 3.7535 0.2493
ME-180 GDSC1 8.0269 10.3589 3.5702 0.398
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 ClinicalTrials.gov (NCT00735332) Efficacy Study of TLN-232 in Patients With Recurring Metastatic Melanoma. U.S. National Institutes of Health.
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.