Details of the Drug

General Information of Drug (ID: DMRC49E)

Drug Name
4-fluoroselegiline
Synonyms CH-175; SR-96516; P-Fluoro-Selegiline; P-Fluoro-Selegiline hydrochloride
Indication
Disease Entry ICD 11 Status REF
Dementia 6D80-6D86 Investigative [1]
Structure
3D MOL 2D MOL
Cross-matching ID
PubChem CID
9794264
TTD ID
D07KIB

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type B (MAO-B) TTGP7BY AOFB_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Dementia
ICD Disease Classification 6D80-6D86
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type B (MAO-B) DTT MAOB 2.65E-02 1.12E-02 0.07
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Multiple, small dose administration of (-)deprenyl enhances catecholaminergic activity and diminishes serotoninergic activity in the brain and these effects are unrelated to MAO-B inhibition. Arch Int Pharmacodyn Ther. 1994 Jul-Aug;328(1):1-15.