Details of the Drug

General Information of Drug (ID: DMRCHOU)

Drug Name
H-103
Synonyms Oncolytic adenovirus (metastasis), Shanghai Sunway Biotech
Indication
Disease Entry ICD 11 Status REF
Metastatic malignant neoplasm 2D50-2E09 Phase 1 [1]
Cross-matching ID
TTD ID
D0VZ1C

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heat shock protein 70 (HSP70) TTHYBIX HS71A_HUMAN ; HS71B_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Metastatic malignant neoplasm
ICD Disease Classification 2D50-2E09
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Heat shock protein 70 (HSP70) DTT HSPA1A; HSPA1B 1.03E-20 0.32 1.2
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients. Gene Ther. 2009 Mar;16(3):376-82.