Details of the Drug

General Information of Drug (ID: DMREDYP)

Drug Name
ABT-869
Synonyms
Linifanib; ABT 869; S1003_Selleck; AL-39324; RG-3635; ABT869, Linifanib, AL-39324, RG3635; N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea; N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 3 [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 375.4
Logarithm of the Partition Coefficient (xlogp) 3.9
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C21H18FN5O
IUPAC Name
1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
Canonical SMILES
CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
InChI
InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
InChIKey
MPVGZUGXCQEXTM-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11485656
ChEBI ID
CHEBI:91435
CAS Number
796967-16-3
UNII
CO93X137CW
DrugBank ID
DB06080
TTD ID
D0M9QZ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Vascular endothelial growth factor receptor 3 (FLT-4) TTDCBX5 VGFR3_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vascular endothelial growth factor receptor 3 (FLT-4) DTT FLT4 6.00E-01 -0.04 -0.23
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.1867 4.9365 -0.5254 0.1882
EW-18 GDSC1 1.0983 3.5394 -0.9308 4.5063
ES8 GDSC1 1.3268 4.0541 -1.0279 4.6819
CHSA8926 GDSC1 1.4507 5.4933 -1.6243 8.6144
EW-1 GDSC1 1.5997 3.9821 -0.8383 2.8699
EW-7 GDSC1 1.6838 4.3891 -0.9707 3.5741
EW-24 GDSC1 1.9358 3.2311 -0.386 0.2871
TC-71 GDSC1 1.9685 3.6136 -0.5125 0.6813
HuO9 GDSC1 2.0242 12.1486 -4.4552 22.5801
SK-N-MC CTRP2 2.1357 2.8981 2.1357 26.0406
CADO-ES1 GDSC1 2.2222 4.0054 -0.5553 0.6624
SK-PN-DW GDSC1 2.2661 4.2117 -0.6145 0.8561
H-EMC-SS GDSC1 2.2838 5.2437 -1.0207 2.8962
CAL-72 GDSC1 2.314 3.9476 -0.4982 0.4232
A-673 GDSC1; CTRP2 2.4438 3.0446 2.4438 23.9879
Hs 888.T CTRP2 2.4745 9.1547 1.0113 28.7734
ES1 GDSC1 2.5327 4.5079 -0.6164 0.6767
CHSA0011 GDSC1 2.5558 9.8092 -2.9452 14.1121
EW-16 GDSC1 2.5953 4.9087 -0.7409 1.1074
EW-13 GDSC1 2.6647 4.2989 -0.492 0.2667
TC71 CTRP2 2.717 4.1629 2.7087 22.1951
HuO-3N1 GDSC1 2.7468 13.2935 -4.4933 20.8816
ES7 GDSC1 2.771 9.9421 -2.8668 13.166
ES6 GDSC1 2.8938 4.7522 -0.5663 0.3537
MHH-ES-1 GDSC1; CTRP2 2.8974 4.2164 2.8911 20.9865
CHSA0108 GDSC1 2.9503 5.1249 -0.6774 0.6331
ES5 GDSC1 3.0913 5.7385 -0.8476 1.1445
ES4 GDSC1 3.1126 5.1828 -0.6366 0.4404
SaOS-2 GDSC1; CTRP2 3.167 4.3456 3.162 19.1861
NY GDSC1 3.1754 5.2361 -0.6322 0.4045
SK-ES-1 GDSC1; CTRP2 3.1877 4.4242 3.1807 19.055
U2OS GDSC1; CTRP2 3.2635 4.4598 3.2236 12.8566
EW-3 GDSC1 3.3476 5.4527 -0.6448 0.3711
HOS GDSC1; CTRP2 3.5772 5.8674 3.3981 17.0589
NOS-1 [Human HNSCC] GDSC1 3.6076 16.5177 -5.4528 22.3283
EW-11 GDSC1 3.7973 6.3235 -0.7843 0.5339
SW1353 CTRP2 4.0975 5.2164 3.9594 7.2851
SJSA-1 GDSC1; CTRP2 4.1778 7.1802 3.6145 14.5034
MG-63 GDSC1; CTRP2 4.2125 6.4434 3.9235 13.2353
G-292 clone A141B1 GDSC1; CTRP2 4.5052 8.1952 3.5182 14.0147
CAL-78 GDSC1; CTRP2 4.7202 5.7938 4.3742 3.763
Hs 822.T CTRP2 5.65 5.9368 5.6379 2.6689
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 209 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 2.6644 3.204 2.6644 22.5178
JK1 CTRP2 2.7533 5.3854 2.6088 22.4214
JM1 GDSC1; CTRP2 2.4748 3.3202 2.4747 23.7817
EoL-1 GDSC1; CTRP2 -10.4577 -5.0187 -10.464 92.8218
MV4-11 GDSC1; CTRP2 -7.0571 -4.5189 -7.0572 85.9351
NKM-1 GDSC1 -7.0145 -4.7113 -7.0171 83.6833
MOLM-13 GDSC1; CTRP2 -6.2436 -3.6056 -6.2437 81.0762
Kasumi-1 GDSC1; CTRP2 -4.7242 -0.1205 -4.7487 70.0921
ALL-PO GDSC1 -3.4196 2.1717 -4.4763 45.5306
Loucy GDSC1 -2.9867 -1.7419 -2.9922 37.7945
GDM-1 GDSC1; CTRP2 -2.9751 11.2336 -6.7306 50.0679
SEM CTRP2 -2.6242 3.9053 -2.9295 56.5799
AML-193 CTRP2 -2.433 -1.0937 -2.433 56.4778
VL51 GDSC1 -1.8004 -0.7244 -1.823 23.0759
KE-97 CTRP2 -1.1855 -0.1869 -1.1855 48.1665
BE-13 GDSC1 -0.4879 1.0622 -0.9605 9.9657
Mono-Mac-6 GDSC1; CTRP2 -0.2957 21.7371 -7.5562 47.2267
Peer CTRP2 -0.1093 2.0537 -0.1198 36.822
KG-1 GDSC1 0.0613 2.3714 -1.1119 8.935
NOMO-1 GDSC1 0.3077 6.8862 -3.1666 21.9815
JVM-2 GDSC1 0.3251 5.3892 -2.4049 17.4302
P32/ISH GDSC1 0.4302 3.1217 -1.1932 8.3217
SCC-3 GDSC1 1.1621 2.581 -0.4674 1.2975
Ramos.2G6.4C10 GDSC1 1.1645 3.2144 -0.7419 3.0387
ML-2 GDSC1 1.2504 3.9162 -1.0112 4.7339
KMS-21-BM CTRP2 1.3087 3.0402 1.295 26.7133
LP-1 GDSC1; CTRP2 1.3526 2.6452 1.3522 31.2589
BC-1 GDSC1 1.3804 3.8328 -0.8951 3.6504
ATN-1 GDSC1 1.4161 3.2344 -0.6138 1.7842
BALL-1 GDSC1 1.4596 3.9208 -0.889 3.4545
Hs 445 GDSC1 1.4678 3.5699 -0.7302 2.4112
MOLT-4 GDSC1 1.4813 3.2195 -0.5752 1.4723
BCP-1 CTRP2 1.4869 4.8607 1.3367 30.8641
697 GDSC1; CTRP2 1.4896 2.7841 1.4891 30.3466
MN-60 GDSC1 1.4999 3.338 -0.6152 1.6722
GA-10 CTRP2 1.5332 2.1698 1.5332 30.0542
SU-DHL-16 GDSC1 1.5597 3.0178 -0.4583 0.7936
ALL-SIL GDSC1; CTRP2 1.5692 4.0069 1.5305 29.9438
HC-1 GDSC1 1.5752 3.7492 -0.7507 2.3639
CTV-1 GDSC1 1.5754 3.9869 -0.8536 3.0101
ARH-77 GDSC1 1.5855 3.8455 -0.7867 2.5695
RPMI-8226 GDSC1; CTRP2 1.5909 4.198 1.0458 14.6905
Karpas-231 GDSC1 1.5949 2.9995 -0.4361 0.667
KCL-22 GDSC1; CTRP2 1.5978 3.5299 1.5867 29.661
TK [Human B-cell lymphoma] GDSC1 1.5989 3.1637 -0.4979 0.938
HuT 78 CTRP2 1.6108 4.4343 1.5318 29.8022
SUP-M2 GDSC1; CTRP2 1.6194 2.0792 1.6194 29.4797
Karpas-45 GDSC1 1.6217 4.4221 -1.0205 4.0207
ME1 GDSC1 1.6437 2.9453 -0.3956 0.4737
KOPN-8 GDSC1 1.7076 4.193 -0.8718 2.8987
YT GDSC1 1.7154 3.0618 -0.41 0.4777
CA46 GDSC1; CTRP2 1.7267 4.1284 1.6854 28.9039
MEG-01 GDSC1 1.7366 4.2254 -0.8703 2.8412
SUP-T1 GDSC1; CTRP2 1.7455 2.6892 1.7064 11.0461
DND-41 GDSC1; CTRP2 1.7629 3.7331 1.7479 28.5742
A3/Kawakami GDSC1; CTRP2 1.7666 2.2472 1.7666 28.4992
OPM-2 GDSC1; CTRP2 1.7824 2.6664 1.7824 28.3938
EB1 CTRP2 1.7827 4.5572 1.6991 28.6735
TUR GDSC1 1.8167 4.0253 -0.7444 1.9694
Farage GDSC1 1.8333 3.2074 -0.4166 0.4283
SU-DHL-5 GDSC1 1.8548 3.0222 -0.3426 0.2123
Hs 611.T CTRP2 1.8934 3.4785 1.8888 27.6699
KMS-12-BM GDSC1; CTRP2 1.9027 2.679 1.9027 27.5926
NB4 GDSC1; CTRP2 1.9239 2.692 1.8973 9.5084
Namalwa GDSC1; CTRP2 1.9331 3.2934 1.9315 27.3952
Pfeiffer CTRP2 1.943 2.7597 1.943 27.3239
JSC-1 GDSC1 1.9664 3.9909 -0.6594 1.334
WSU-NHL GDSC1 1.9776 3.5856 -0.4983 0.6212
BC-3 GDSC1 1.9834 3.895 -0.6139 1.0996
Jiyoye GDSC1 2.0263 3.8914 -0.5938 0.9695
KY821 GDSC1 2.0462 3.7094 -0.5165 0.6408
DG-75 GDSC1 2.0561 3.9969 -0.6217 1.066
SR GDSC1; CTRP2 2.0586 3.1766 2.0558 21.3217
WIL2 NS GDSC1 2.0752 3.5029 -0.4301 0.3437
RC-K8 GDSC1 2.0762 3.4674 -0.4171 0.3086
CCRF-CEM GDSC1 2.087 3.6466 -0.4772 0.479
H9 GDSC1 2.1078 3.931 -0.5743 0.8189
P30/OHK GDSC1 2.2148 3.7981 -0.4825 0.4265
MOLT-3 CTRP2 2.2538 2.9813 2.2538 25.2536
A4/Fukuda GDSC1; CTRP2 2.2597 3.0049 2.2597 25.214
EJM GDSC1; CTRP2 2.2829 3.4384 2.2821 25.0621
MHH-PREB-1 GDSC1 2.3328 3.9434 -0.4896 0.3898
Sc-1 GDSC1 2.3397 3.806 -0.4388 0.2595
RS4;11 GDSC1; CTRP2 2.364 3.2639 2.3639 24.5195
Ri-1 CTRP2 2.3676 3.6969 2.3648 24.5048
SU-DHL-1 GDSC1; CTRP2 2.3749 2.9548 2.3749 19.0539
HDLM-2 GDSC1; CTRP2 2.3804 3.6694 2.3781 24.4177
QIMR-WIL GDSC1 2.3999 4.2738 -0.5831 0.6454
BL-70 CTRP2 2.4051 3.0187 2.4051 24.2456
EB2 GDSC1 2.4149 4.0274 -0.4887 0.351
SU-DHL-4 GDSC1; CTRP2 2.4384 4.4431 2.404 24.1396
NALM-6 GDSC1; CTRP2 2.4438 3.1598 2.4438 23.9876
Kasumi-2 CTRP2 2.4442 2.9967 2.4442 23.9848
DEL GDSC1; CTRP2 2.4474 2.8403 2.4474 23.9635
EM-2 GDSC1; CTRP2 2.4596 3.3754 2.458 18.4551
OCI-AML-3 GDSC1; CTRP2 2.4735 3.0293 2.4735 23.7899
RCH-ACV CTRP2 2.477 4.1544 2.4628 23.8141
Karpas-299 GDSC1; CTRP2 2.4778 3.0633 2.4778 18.3194
MOLM-16 CTRP2 2.4789 4.6365 2.4282 23.9249
ST486 GDSC1; CTRP2 2.485 3.1278 2.485 23.7132
HH [Human lymphoma] GDSC1 2.4881 4.4499 -0.6128 0.6926
LC4-1 GDSC1 2.4979 4.4874 -0.6227 0.7212
PL-21 GDSC1 2.4995 4.7697 -0.7284 1.1359
RPMI-8866 GDSC1 2.5137 4.141 -0.492 0.3199
SU-DHL-8 GDSC1; CTRP2 2.524 3.6639 2.5228 23.4574
KMS-34 CTRP2 2.5275 3.0377 2.5275 23.43
NCI-H929 CTRP2 2.528 3.6835 2.5267 23.431
Jurkat CTRP2 2.5335 3.3733 2.5334 23.3902
SU-DHL-6 GDSC1; CTRP2 2.534 3.2564 2.5339 23.3871
JeKo-1 CTRP2 2.547 2.9745 2.547 23.3001
Granta-519 GDSC1; CTRP2 2.5476 5.1542 2.4293 23.6996
RPMI-8402 GDSC1; CTRP2 2.5599 3.3946 2.5589 17.7371
RL GDSC1; CTRP2 2.5657 4.1382 2.5547 23.2123
MOLP-8 GDSC1; CTRP2 2.5662 3.2105 2.5662 23.1723
KMS-11 GDSC1; CTRP2 2.5672 3.5347 2.5641 17.6925
M-07e CTRP2 2.5728 3.9007 2.569 23.1408
OCI-Ly19 GDSC1; CTRP2 2.5737 4.6398 2.5279 23.2767
Daudi GDSC1; CTRP2 2.5766 3.6536 2.5757 23.106
HEL 92.1.7 CTRP2 2.5824 2.9464 2.5824 23.0646
CESS GDSC1 2.599 4.2516 -0.4994 0.3055
MLMA GDSC1 2.6087 4.5004 -0.5839 0.5279
KO52 CTRP2 2.6088 4.1254 2.5994 22.9198
PL21 CTRP2 2.6113 3.8327 2.5382 11.5979
Reh GDSC1; CTRP2 2.6178 3.4252 2.4424 4.4376
KHM-1B CTRP2 2.6191 3.2312 2.619 17.3112
K-562 GDSC1; CTRP2 2.6222 3.8361 2.62 22.8064
JURL-MK1 GDSC1; CTRP2 2.6334 3.6927 2.6326 22.7273
DB GDSC1; CTRP2 2.6429 3.5862 2.6426 22.6625
TF-1 CTRP2 2.6475 3.0625 2.6475 22.6306
KM-H2 GDSC1; CTRP2 2.657 4.6655 2.6132 22.7149
SKM-1 CTRP2 2.6596 3.1824 2.6595 17.0223
U-937 CTRP2 2.6615 3.5109 2.6599 17.0138
KMS-26 CTRP2 2.6767 3.1459 2.6767 22.4358
L-363 GDSC1; CTRP2 2.6773 3.2445 2.6773 16.8955
Ki-JK CTRP2 2.6841 3.378 2.6837 16.8482
SK-MM-2 GDSC1; CTRP2 2.6937 3.6166 2.6934 22.324
KMOE-2 GDSC1 2.6999 4.4933 -0.547 0.3821
U-698-M GDSC1 2.7319 4.5067 -0.5398 0.3516
U266B1 GDSC1; CTRP2 2.7365 3.5872 2.7364 22.0381
Raji GDSC1; CTRP2 2.7431 3.433 2.5683 3.4063
JJN-3 GDSC1; CTRP2 2.7469 3.4051 2.7468 21.9687
MOLT-16 GDSC1; CTRP2 2.7543 3.94 2.7519 21.9272
BV-173 GDSC1; CTRP2 2.7579 3.7331 2.7528 16.3382
CTB-1 GDSC1 2.7682 4.915 -0.6723 0.722
LAMA-84 GDSC1; CTRP2 2.77 4.0952 2.7647 21.832
SIG-M5 GDSC1; CTRP2 2.7761 4.1731 2.7687 21.7985
ROS-50 GDSC1 2.7784 4.9015 -0.6634 0.6857
TALL-1 [Human adult T-ALL] CTRP2 2.7845 5.0661 2.6983 22.0108
Mono-Mac-1 CTRP2 2.7922 15.0176 -1.3749 33.859
OCI-AML-2 GDSC1; CTRP2 2.7949 4.0568 2.7724 16.1372
WSU-DLCL2 GDSC1; CTRP2 2.7967 3.4785 2.7967 21.6366
OCI-AML-5 GDSC1; CTRP2 2.8061 4.0018 2.8033 21.5834
Ci-1 CTRP2 2.8062 4.2408 2.7971 21.6034
HEL GDSC1; CTRP2 2.8332 3.4415 2.8332 21.3932
MY-M12 GDSC1 2.8391 4.6541 -0.5521 0.3405
P31/FUJ GDSC1; CTRP2 2.8701 4.8512 2.7213 16.0722
L-540 GDSC1; CTRP2 2.8841 3.875 2.8833 21.0573
MOLM-6 CTRP2 2.8846 4.5026 2.8647 21.118
MM1.S CTRP2 2.8847 3.727 2.882 15.4247
VAL GDSC1 2.8877 4.8793 -0.6133 0.4762
KMS-20 CTRP2 2.9222 4.0439 2.92 20.8079
CML-T1 CTRP2 2.9235 3.7638 2.9205 15.1488
SUP-T11 CTRP2 2.938 4.3895 2.9261 20.7351
F-36P CTRP2 2.9704 4.1354 2.9672 20.49
L-1236 GDSC1 2.9789 5.1595 -0.6789 0.6222
HAL-01 GDSC1 3.0104 4.7498 -0.5237 0.2279
KMS-27 CTRP2 3.0143 3.7091 3.0142 20.1874
ME1 CTRP2 3.0481 6.352 1.3995 8.6883
AMO1 GDSC1; CTRP2 3.0624 3.9659 3.0619 19.8681
NCO2 CTRP2 3.0638 4.1564 3.0456 14.2024
KE-37 GDSC1; CTRP2 3.1061 3.8977 3.1059 19.576
PF-382 GDSC1; CTRP2 3.1604 4.1519 3.1589 19.2185
L-428 GDSC1; CTRP2 3.1672 4.9753 3.1188 19.332
Ku812 GDSC1; CTRP2 3.1896 4.6201 3.1736 19.0729
JVM-3 GDSC1; CTRP2 3.2147 4.5152 3.1632 13.2474
HT GDSC1; CTRP2 3.2349 4.048 3.2294 12.9354
NU-DUL-1 GDSC1; CTRP2 3.2801 4.9269 2.8908 7.8681
P12-Ichikawa GDSC1; CTRP2 3.3385 4.2554 3.3372 18.0316
KYO-1 CTRP2 3.3638 5.017 3.3223 17.9989
MOLP-2 CTRP2 3.3693 4.5302 3.3267 12.1116
MOLT-13 GDSC1; CTRP2 3.4328 4.9501 2.3994 2.6174
MHH-CALL-4 CTRP2 3.4916 4.3919 3.49 17.0122
KMS-18 CTRP2 3.4983 4.736 3.4862 17.0028
SU-DHL-10 GDSC1; CTRP2 3.5058 5.2548 3.4427 17.1269
GR-ST GDSC1 3.5638 5.5678 -0.6074 0.2353
CMK CTRP2 3.5691 5.3304 3.4991 16.7291
THP-1 GDSC1; CTRP2 3.589 5.1684 3.4205 11.0247
MOTN-1 CTRP2 3.7232 5.3417 3.6627 15.6701
OCI-M1 GDSC1; CTRP2 3.7686 5.5859 3.6692 15.5025
EHEB CTRP2 3.843 5.0471 3.7326 8.9889
MHH-CALL-3 CTRP2 3.8499 6.8517 3.0211 11.9246
SUP-HD1 GDSC1; CTRP2 3.8916 5.6114 3.7975 14.6649
NU-DHL-1 CTRP2 4.0006 5.0744 3.9859 13.6656
SUP-B15 GDSC1; CTRP2 4.0484 5.4241 3.9988 13.466
SET-2 CTRP2 4.1438 5.4222 4.101 12.807
HD-MY-Z CTRP2 4.2342 6.9672 3.7578 13.7978
RPMI-6666 GDSC1; CTRP2 4.4523 5.9247 4.3381 11.0034
HPB-ALL CTRP2 4.4595 5.706 4.394 10.7833
HL-60 GDSC1; CTRP2 4.528 6.0216 4.3957 10.5647
Toledo CTRP2 4.533 7.6189 3.8028 12.8136
OCI-Ly3 CTRP2 4.6316 6.525 4.3489 10.4308
BL-41 GDSC1; CTRP2 4.8612 11.7939 2.1326 18.6175
P3HR-1 CTRP2 5.1507 8.4579 4.0308 10.3621
Karpas-422 GDSC1; CTRP2 5.2725 5.9787 5.219 5.3281
KMM-1 CTRP2 5.3767 8.1072 3.7803 5.0414
REC-1 CTRP2 5.7396 9.8811 3.8665 9.7552
Karpas-620 GDSC1; CTRP2 5.9561 7.5458 4.447 1.2894
OCI-Ly10 CTRP2 6.6416 8.2715 5.3806 1.8263
MC116 GDSC1; CTRP2 7.219 11.8717 4.0421 6.3949
⏷ Show the Full List of 209 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.9972 4.2275 2.9924 20.3169
TE15 CTRP2 3.8754 5.944 3.704 15.0472
KYSE-270 GDSC1 1.4619 4.1504 -0.9909 4.1388
TE-8 GDSC1 1.8042 4.1151 -0.7883 2.2397
T.T GDSC1 2.1479 3.6863 -0.468 0.4175
TE-15 GDSC1 2.1824 4.1486 -0.6257 0.9707
TE-6 GDSC1; CTRP2 2.2383 3.3454 2.2378 25.3584
TE-11 GDSC1; CTRP2 2.6056 4.4012 2.5817 22.99
KYSE-180 GDSC1; CTRP2 2.7386 3.4864 2.7385 22.024
TE-4 GDSC1; CTRP2 3.0222 4.6109 3.0004 20.2073
KYSE-140 GDSC1; CTRP2 3.1222 4.7732 3.0921 19.5694
OE21 GDSC1; CTRP2 3.3514 4.8938 3.3217 18.0409
TE-10 GDSC1; CTRP2 3.4413 4.9015 3.4154 17.4292
TE-9 GDSC1; CTRP2 3.4718 4.1076 3.4717 17.1391
EC-GI-10 GDSC1; CTRP2 3.4923 5.595 3.3678 17.4304
KYSE-410 GDSC1; CTRP2 3.4979 5.6356 3.165 12.3277
KYSE-510 GDSC1; CTRP2 3.6022 5.1665 3.5575 16.4214
KYSE-150 GDSC1; CTRP2 3.6071 5.2855 3.5467 16.4429
TE-14 CTRP2 3.627 5.6024 3.5125 16.4986
KYSE-70 GDSC1; CTRP2 3.6362 5.2896 2.3755 2.3728
COLO 680N GDSC1; CTRP2 3.7415 5.6603 3.6247 15.7444
TE-1 GDSC1; CTRP2 3.7684 5.3564 3.5556 9.9227
KYSE-30 CTRP2 3.8526 5.657 3.746 14.9687
TE-5 GDSC1; CTRP2 3.9942 6.0229 3.8128 14.2929
OE19 GDSC1; CTRP2 4.6961 6.5681 4.4028 10.043
KYSE-450 GDSC1; CTRP2 4.7606 5.9379 4.671 8.8636
OE33 GDSC1; CTRP2 4.7881 6.8258 4.4021 9.7882
KYSE-520 GDSC1; CTRP2 4.9762 7.9293 4.1112 10.4532
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.3186 6.4708 4.0294 12.5318
PL4 GDSC1 1.6785 3.6057 -0.6386 1.5647
HPAC GDSC1; CTRP2 2.1663 3.1681 2.0516 7.8859
HuP-T4 GDSC1; CTRP2 2.2501 5.6759 1.8017 21.6513
SNU-213 CTRP2 2.3888 5.4289 2.0328 20.3042
PSN1 GDSC1; CTRP2 2.7361 4.788 2.6835 22.2179
MZ-PC-1 GDSC1 2.7768 4.9247 -0.6725 0.7173
L3.3 CTRP2 2.8981 3.5164 2.8978 15.3207
BxPC-3 GDSC1; CTRP2 2.9556 4.4802 2.8904 15.1473
DAN-G GDSC1; CTRP2 3.0624 6.2096 2.7435 20.9857
QGP-1 GDSC1; CTRP2 3.2081 4.2435 3.1893 13.1748
Panc 08.13 GDSC1; CTRP2 3.2353 5.3603 3.1347 19.0584
PK-59 CTRP2 3.3194 5.2427 3.1042 13.1276
KP-4 GDSC1; CTRP2 3.3564 4.4981 3.3505 17.9274
YAPC GDSC1; CTRP2 3.4866 4.6988 2.5574 1.7239
Panc 10.05 GDSC1; CTRP2 3.5454 5.2541 3.4853 16.8527
HPAF-II GDSC1; CTRP2 3.6777 6.6147 2.9532 12.6857
Panc 03.27 GDSC1; CTRP2 3.6908 5.8817 3.5184 16.2789
TCC-Pan2 CTRP2 3.7091 5.6709 2.2423 2.9104
Capan-2 GDSC1; CTRP2 3.793 6.0488 3.5861 15.723
KP-3 GDSC1; CTRP2 3.8085 6.2144 3.5559 15.7856
MIA PaCa-2 GDSC1; CTRP2 3.8236 5.826 3.6768 15.3039
Hs 766T GDSC1; CTRP2 3.8868 5.3946 3.8301 14.5668
PaTu 8988s CTRP2 3.9045 5.7151 3.7901 14.6505
Capan-1 GDSC1; CTRP2 4.0534 7.4633 3.3689 15.7915
PANC-1 CTRP2 4.0556 6.4129 3.7632 14.2898
PaTu 8988t GDSC1; CTRP2 4.0706 5.6462 3.9845 13.4451
Panc 05.04 CTRP2 4.1143 8.2706 1.2671 7.0902
SU.86.86 GDSC1; CTRP2 4.1872 5.5638 4.1257 12.5826
CFPAC-1 GDSC1; CTRP2 4.4604 7.4293 3.8091 12.9808
SW1990 GDSC1; CTRP2 4.5345 6.9664 4.0775 11.7374
HuP-T3 GDSC1; CTRP2 4.6101 6.6045 4.2971 10.6877
AsPC-1 GDSC1; CTRP2 4.8591 6.8212 4.4791 9.2959
PaTu 8902 GDSC1; CTRP2 4.9388 6.7228 4.1157 4.4061
SNU-410 CTRP2 4.9539 9.8932 3.1497 14.419
SUIT-2 GDSC1; CTRP2 4.9685 5.8499 4.917 7.3449
Panc 04.03 GDSC1; CTRP2 5.143 7.26 4.5849 8.1296
PK-45H CTRP2 5.5153 8.2624 4.4686 7.7208
KP-2 GDSC1; CTRP2 6.0748 8.7004 4.7417 5.4173
Panc 02.03 GDSC1; CTRP2 6.4794 10.2089 4.3127 6.4803
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.3058 5.6166 2.0727 25.7081
WT2-iPS GDSC1; CTRP2 -1.5245 -0.9185 -1.5245 50.4253
LB2518-MEL GDSC1 0.7751 2.2378 -0.5285 2.3642
MZ-MEL-2 GDSC1 0.972 3.1142 -0.812 3.943
CP66-MEL GDSC1 1.1188 2.7973 -0.5825 2.0675
SK-MEL-2 GDSC1 1.1982 2.2568 -0.3208 0.515
GAK GDSC1 1.4045 3.1105 -0.5677 1.5338
A-431 GDSC1 1.4341 3.213 -0.5958 1.6529
MMAc-SF GDSC1 1.4597 3.2039 -0.5793 1.5239
VMRC-MELG GDSC1 1.5132 3.4026 -0.6355 1.7702
LB373-MEL-D GDSC1 1.5797 2.8134 -0.3726 0.434
451Lu GDSC1 1.6393 3.6838 -0.6901 1.9065
SH-4 GDSC1 1.6438 3.9059 -0.7819 2.4457
WM35 GDSC1 1.6937 3.7562 -0.6933 1.8488
Hs 938.T GDSC1 1.6969 3.2936 -0.5054 0.8778
DJM-1 GDSC1 1.7653 3.5347 -0.5696 1.1094
WM1552C GDSC1 1.7895 3.9741 -0.7366 1.9624
COLO 679 GDSC1 1.8225 3.6387 -0.5849 1.1239
COLO 783 GDSC1 1.8255 3.2781 -0.4457 0.5326
HMV-II GDSC1 1.878 4.6238 -0.9673 3.2113
MZ-MEL-7 GDSC1 1.9113 4.1348 -0.7434 1.8381
M14 GDSC1 1.9439 3.4705 -0.4693 0.5389
G-mel GDSC1 1.9499 3.5594 -0.4999 0.6466
Hs 940.T GDSC1 2.0161 3.6426 -0.5039 0.6151
WM278 GDSC1 2.0748 4.2581 -0.7163 1.4984
CP50-MEL-B GDSC1 2.1203 3.6918 -0.4806 0.4711
CHL-1 GDSC1 2.2793 4.1215 -0.5753 0.6966
IST-MEL1 GDSC1 2.3862 9.9919 -3.1471 15.6206
A-388 GDSC1 2.663 4.7125 -0.6398 0.6762
LOX-IMVI GDSC1; CTRP2 2.7743 4.0139 2.7709 21.7972
Malme-3M CTRP2 2.9091 5.7712 2.6933 21.6354
MeWo GDSC1; CTRP2 3.1152 5.2306 3.0275 19.8135
RPMI-7951 GDSC1; CTRP2 3.175 4.141 3.1737 19.1207
G-361 GDSC1; CTRP2 3.2354 4.3315 2.5587 2.1877
Hs 936.T CTRP2 3.3921 4.5545 2.5628 1.8626
Mel JuSo GDSC1; CTRP2 3.5338 5.4152 3.2815 11.7484
SK-MEL-1 GDSC1; CTRP2 3.6585 5.0774 3.6271 16.001
IGR-37 GDSC1; CTRP2 3.6935 5.1782 3.6531 15.7986
WM983B CTRP2 3.8108 6.1509 3.5769 15.7021
WM793 GDSC1; CTRP2 3.8738 4.9023 3.8027 8.6189
HT-144 GDSC1; CTRP2 3.9497 5.6742 3.8478 14.3057
A-375 GDSC1; CTRP2 3.9603 5.3652 3.913 14.0449
SK-MEL-30 GDSC1; CTRP2 3.9644 5.7817 3.6062 9.1243
IPC-298 GDSC1; CTRP2 3.978 6.4627 3.3266 10.2665
Mel Ho GDSC1; CTRP2 3.9799 5.1763 3.9558 13.8352
Hs 944.T CTRP2 4.1116 5.7553 4.0064 13.2393
A2058 GDSC1; CTRP2 4.2156 5.4932 4.1676 12.3471
WM266-4 CTRP2 4.2524 5.3063 4.23 12.0141
MDA-MB-435S CTRP2 4.2992 5.382 4.1192 6.0194
COLO 792 GDSC1; CTRP2 4.3057 6.9565 3.8382 13.2906
HMCB CTRP2 4.3236 5.6527 4.257 11.692
WM1799 CTRP2 4.3392 6.0126 3.8948 6.8474
SK-MEL-3 GDSC1; CTRP2 4.3499 5.7352 4.2695 11.5655
SK-MEL-5 GDSC1; CTRP2 4.3763 5.3411 4.2171 5.3879
Hs 294T CTRP2 4.4406 5.8124 4.3515 10.9921
CJM [Human melanoma] CTRP2 4.4959 5.7606 4.4227 10.568
IGR-1 GDSC1; CTRP2 4.6892 7.4248 4.0481 11.4357
WM88 CTRP2 4.898 6.5171 4.6386 8.5773
COLO 829 GDSC1; CTRP2 5.0531 10.5959 2.8976 15.209
RVH-421 GDSC1; CTRP2 5.1075 9.0323 3.7124 11.7698
A101D GDSC1; CTRP2 5.1596 5.8553 5.1231 6.0198
SK-MEL-24 GDSC1; CTRP2 5.2174 6.6321 4.9337 6.558
K029AX CTRP2 5.223 6.4427 5.0147 6.231
COLO 800 GDSC1; CTRP2 5.262 7.0765 4.7879 7.0155
IGR-39 CTRP2 5.2731 8.4547 4.1486 9.5936
Hs 852.T CTRP2 5.2886 6.7923 2.5658 0.2131
UACC-62 GDSC1; CTRP2 5.3593 9.4752 3.7292 11.134
UACC-257 GDSC1; CTRP2 5.3912 7.1501 4.8839 6.3049
Hs 688(A).T CTRP2 5.3934 5.9761 5.3513 4.4829
WM115 GDSC1; CTRP2 5.5 5.9175 5.4795 3.6971
Hs 934.T CTRP2 5.6353 6.0164 5.6052 2.8302
Hs 895.T CTRP2 5.6825 12.6959 2.4125 15.7643
SK-MEL-28 GDSC1; CTRP2 5.9034 7.1519 4.5911 0.8082
SK-MEL-31 CTRP2 6.3861 8.0414 4.4613 0.8372
Hs 839.T CTRP2 10.2375 28.2709 -1.7977 20.668
EquiPSC Line K2 GDSC1 2.9953 5.3416 -0.7388 0.8086
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC1 0.5452 2.0509 -0.5866 3.3256
ESO-26 GDSC1 1.3624 3.3917 -0.7095 2.4584
OACP4 C GDSC1 1.4368 4.3379 -1.0915 4.887
TE-12 GDSC1 1.4582 3.8871 -0.8748 3.3629
ESO-51 GDSC1 1.6924 3.8188 -0.7201 2.0041
HCE-4 GDSC1 1.9689 4.1056 -0.7042 1.5578
OACM5.1 C GDSC1 2.0122 7.1156 -2.0249 9.9248
FLO-1 GDSC1 2.2684 4.61 -0.768 1.5432
KYSE-220 GDSC1 2.4889 5.1203 -0.8707 1.8111
KYAE-1 GDSC1 2.6652 10.1784 -3.0483 14.4042
SK-GT-4 GDSC1 2.7821 6.5651 -1.3254 3.9302
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 3.0691 5.173 2.9871 20.1007
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-17 GDSC1 0.4302 2.1889 -0.7336 4.7627
LA-N-6 GDSC1 0.9214 3.7268 -1.1352 6.4466
MHH-NB-11 GDSC1 1.2368 5.6804 -1.8603 10.8419
IMR-5 GDSC1 1.319 3.7984 -0.9156 3.9155
SK-N-MC-IXC GDSC1 1.3834 2.8054 -0.4534 0.9482
SJNB-13 GDSC1 1.3873 3.3053 -0.6589 2.0998
SK-N-DZ GDSC1 1.4376 3.9362 -0.9085 3.6282
NB(TU)1 GDSC1 1.5007 3.356 -0.6223 1.7118
TGW GDSC1 1.5462 3.2101 -0.5404 1.2054
NH-12 GDSC1 1.5576 3.3706 -0.6004 1.5113
SJNB-10 GDSC1 1.6668 3.7196 -0.6914 1.8753
SJNB-7 GDSC1 1.6679 3.4459 -0.5787 1.2614
SJNB-12 GDSC1 1.8861 4.7969 -1.0384 3.6469
SK-N-BE(2)-M17 GDSC1 1.9235 3.7541 -0.5853 1.0262
SJNB-6 GDSC1 1.9309 3.678 -0.5527 0.8753
KP-N-YS GDSC1 1.9435 3.986 -0.6679 1.4018
SK-N-FI GDSC1; CTRP2 2.0204 3.2102 2.0198 26.8104
CHP-134 GDSC1 2.0447 3.5138 -0.4456 0.4033
SJNB-5 GDSC1 2.1213 3.9521 -0.5767 0.8177
SiMa GDSC1; CTRP2 2.1418 3.9565 2.1273 26.048
IMR-32 CTRP2 2.1917 3.1373 2.1916 25.6675
NB69 GDSC1 2.2498 9.3892 -2.9504 14.9071
SJNB-14 GDSC1 2.2658 3.7025 -0.4297 0.265
NB1 GDSC1; CTRP2 2.3336 2.9881 2.3336 19.3487
GOTO GDSC1 2.4044 4.8591 -0.8051 1.5792
Kelly GDSC1; CTRP2 2.4721 3.1993 2.4719 18.3609
SK-N-SH GDSC1; CTRP2 2.4843 4.3748 2.4573 23.8085
CHP-212 GDSC1; CTRP2 2.6119 4.1899 2.5999 22.908
NH-6 CTRP2 2.6556 4.5494 2.6225 22.6878
SK-N-BE(2) CTRP2 2.6672 5.3185 2.5285 22.9742
CHP-126 GDSC1; CTRP2 2.9849 4.1858 2.9808 20.3966
KP-N-SI9s CTRP2 3.3231 4.7666 3.2338 12.6157
GI-ME-N GDSC1 3.7365 14.0278 -4.1698 17.2754
SK-N-AS GDSC1; CTRP2 4.1702 5.8779 4.042 12.9306
KP-N-YN GDSC1; CTRP2 4.8933 6.3194 4.7036 8.3468
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 2.6874 5.1482 2.5809 22.7276
HuCC-T1 GDSC1; CTRP2 3.0024 6.5559 2.5721 21.7881
SNU-1196 CTRP2 3.5298 6.1693 3.265 17.6828
SNU-1079 CTRP2 3.6875 5.6615 3.5658 16.1209
SNU-245 CTRP2 3.9561 6.2136 3.717 14.7551
SNU-308 CTRP2 4.1298 5.6029 4.0568 13.0051
SNU-869 CTRP2 4.3901 7.5737 3.6746 13.6949
HuH-28 CTRP2 4.9013 6.0705 4.7897 8.0065
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 89 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-BR-3 CTRP2 0.5325 6.5141 -0.1055 38.4249
HCC70 GDSC1 1.4108 3.1095 -0.5642 1.5051
BT-483 GDSC1 1.4715 4.743 -1.2574 5.9731
HCC1187 GDSC1 1.6137 4.6726 -1.1383 4.8343
EFM-19 GDSC1 1.6382 4.8106 -1.1866 5.1132
MDA-MB-175-VII GDSC1 1.7059 3.9713 -0.7776 2.323
MFM-223 GDSC1 1.8534 3.3041 -0.4441 0.5088
DU4475 GDSC1; CTRP2 1.885 2.6223 1.885 27.7107
HCC1569 GDSC1 1.9001 4.4676 -0.8885 2.6911
OCUB-M GDSC1 1.9335 3.7895 -0.5948 1.0597
MDA-MB-436 GDSC1 1.9364 3.5906 -0.5171 0.7235
MDA-MB-157 GDSC1; CTRP2 1.9682 4.8971 1.8485 27.5612
MRK-nu-1 GDSC1 1.9911 3.2833 -0.3839 0.2592
COLO 824 GDSC1 2.0055 3.9629 -0.6307 1.1557
HCC2157 GDSC1 2.0498 3.382 -0.3969 0.268
MDA-MB-468 GDSC1; CTRP2 2.098 3.1622 2.0977 26.2923
Evsa-T GDSC1 2.1035 3.5944 -0.452 0.3926
MDA-MB-415 GDSC1 2.1164 3.8601 -0.5442 0.6947
HCC2218 GDSC1; CTRP2 2.2511 3.9836 2.2383 25.3143
Hs 578T GDSC1; CTRP2 2.2571 3.6421 2.254 25.242
HCC1599 GDSC1 2.3404 4.0571 -0.5275 0.4973
YMB-1-E GDSC1 2.5299 4.539 -0.6289 0.7224
MDA-MB-453 GDSC1; CTRP2 2.5594 4.1688 2.547 23.259
UACC-812 GDSC1 2.58 4.4468 -0.5757 0.5178
MCF-7 GDSC1; CTRP2 2.623 5.0437 2.402 18.111
MDA-MB-330 GDSC1 2.6398 4.8174 -0.6878 0.8626
HCC1143 CTRP2 2.8757 4.7533 2.7502 15.9437
AU565 GDSC1; CTRP2 2.9528 5.1917 2.8592 20.9156
UACC-893 GDSC1 2.977 5.5874 -0.8381 1.1961
HCC1954 GDSC1; CTRP2 3.1761 5.6045 2.829 14.6708
HCC202 CTRP2 3.1948 7.5706 2.4165 21.799
HMC-1-8 CTRP2 3.3248 4.0247 3.3247 18.1188
BT-474 GDSC1; CTRP2 3.3295 6.0019 3.093 18.9126
HCC1395 GDSC1; CTRP2 3.4245 5.3595 3.3389 17.7462
HCC1806 GDSC1; CTRP2 3.475 4.4384 3.4512 11.288
CAL-85-1 GDSC1; CTRP2 3.5912 6.8502 3.1108 18.0707
CAL-148 GDSC1; CTRP2 3.727 4.7345 3.7212 15.4583
HCC1500 GDSC1; CTRP2 3.7849 8.0066 2.8614 18.4786
ZR-75-1 CTRP2 3.8187 5.4103 2.435 1.7976
CAL-51 GDSC1; CTRP2 3.8629 4.8447 3.8562 14.5557
BT-20 GDSC1; CTRP2 4.0404 5.9727 3.8766 13.922
ZR-75-30 GDSC1; CTRP2 4.0902 6.4375 3.7927 14.0789
CAMA-1 GDSC1; CTRP2 4.2311 8.6615 2.5202 13.1486
HDQ-P1 GDSC1; CTRP2 4.2791 7.2915 3.6766 13.9859
HCC38 GDSC1; CTRP2 4.3779 6.1736 4.1889 11.7684
HCC1937 GDSC1; CTRP2 4.4081 6.9364 3.9551 12.5579
BT-549 GDSC1; CTRP2 4.416 7.8629 3.5759 14.0153
JIMT-1 GDSC1; CTRP2 4.4519 5.6222 4.4008 10.7838
MDA-MB-361 GDSC1; CTRP2 4.5096 7.8076 3.6961 13.2963
EFM-192A GDSC1; CTRP2 4.6409 5.8329 4.5648 9.6128
CAL-120 GDSC1; CTRP2 4.7703 6.4475 4.5262 9.366
T-47D GDSC1; CTRP2 4.9041 8.2934 3.87 11.6071
HCC1428 GDSC1; CTRP2 4.953 6.9279 4.534 8.828
MDA-MB-231 GDSC1; CTRP2 4.9835 8.0981 3.4665 7.2324
HCC1419 GDSC1; CTRP2 5.0366 6.299 4.8658 7.3252
KPL-1 CTRP2 5.1421 5.7215 5.1254 6.5176
Hs 578Bst CTRP2 5.5413 6.0201 5.5018 3.4894
BT 231 CTRP2 2.0022 4.1805 1.9692 27.0405
BT 239 CTRP2 2.4008 4.0977 2.3871 24.3203
BT 416 CTRP2 2.4151 3.1728 2.4151 24.1787
BT164 CTRP2 2.6337 3.0218 2.6337 22.7225
BT 145 CTRP2 2.6395 3.068 2.6395 22.6838
BT 172 CTRP2 2.6541 4.2461 2.6408 22.6311
BT 271 CTRP2 2.6868 8.6112 1.4607 26.6765
BT 228 CTRP2 2.8361 4.3084 2.8251 21.4108
BT 112 CTRP2 2.8494 4.3042 2.8389 21.3206
BT147 CTRP2 2.8856 4.4619 2.8683 21.1022
BT 245 CTRP2 2.937 4.9367 2.879 20.898
BT 504 CTRP2 2.9831 4.2967 2.976 20.4186
BT 428 CTRP2 3.003 4.051 2.5118 2.9644
BT 330 CTRP2 3.0714 6.5693 2.6427 21.3249
BT 131 CTRP2 3.3855 5.9472 3.1686 18.4696
BT 498 CTRP2 3.4881 6.4624 1.6961 6.1405
BT 444 CTRP2 3.5191 5.0036 2.4336 2.2855
BT 422 CTRP2 3.5836 5.1254 3.5428 16.5321
BT 187 CTRP2 3.6547 6.5128 3.295 17.2009
BT 159 CTRP2 3.7176 5.5815 3.6148 15.8542
BT 139 CTRP2 3.7761 5.6429 3.6659 15.4908
BT 359 CTRP2 3.7863 6.2512 3.5207 15.9807
BT 440 CTRP2 3.8254 5.8363 3.6762 15.3003
BT 482 CTRP2 3.9171 5.6378 3.8198 14.5067
BT 328 CTRP2 3.9956 5.8763 3.8521 14.1473
BT 333 CTRP2 4.0539 6.7176 3.6571 14.6904
BT 340 CTRP2 4.0668 7.6393 3.31 15.9831
BT 216 CTRP2 4.4359 6.6714 4.0853 11.9841
BT 320 CTRP2 4.7916 6.5852 4.499 9.4077
BT 224 CTRP2 5.023 7.4229 4.3901 9.214
BT 179 CTRP2 5.0557 6.3431 4.8712 7.2496
BT 232 CTRP2 5.5932 8.8326 4.2585 8.4251
⏷ Show the Full List of 89 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.8244 4.4879 3.824 14.7914
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-247MG GDSC1 0.413 9.8134 -4.5434 27.696
M059J GDSC1 1.1285 3.8669 -1.065 5.4042
KNS-81-FD GDSC1 1.356 4.9131 -1.4112 7.3433
SK-MG-1 GDSC1 1.4019 3.2043 -0.6083 1.7727
D-566MG GDSC1 1.4052 5.6472 -1.7283 9.4619
MOG-G-CCM GDSC1 1.4067 4.5284 -1.1981 5.7034
GI-1 GDSC1 1.7788 4.3554 -0.9041 2.982
LNZTA3WT4 GDSC1 1.8039 3.5134 -0.5441 0.9519
D-423MG GDSC1 1.8873 4.8571 -1.0641 3.8101
Onda 10 GDSC1 1.889 3.9136 -0.6641 1.4441
D-263MG GDSC1 1.9228 3.2898 -0.4118 0.3649
D-336MG GDSC1 1.951 5.697 -1.4041 5.9316
LN-405 GDSC1 2.0257 3.5232 -0.4563 0.4467
D-542MG GDSC1 2.074 3.6052 -0.4672 0.4544
MOG-G-UVW GDSC1 2.1221 4.2204 -0.6799 1.2707
PFSK-1 GDSC1 2.1839 4.1856 -0.6393 1.0277
KNS-60 CTRP2 2.2342 3.2186 2.234 25.3846
D-502MG GDSC1 2.3019 4.2701 -0.6216 0.8567
KINGS-1 GDSC1 2.3393 4.9281 -0.8629 1.945
H4 GDSC1 2.377 4.4713 -0.6664 0.9786
D-392MG GDSC1 2.3807 9.1867 -2.7651 13.5379
SF539 GDSC1; CTRP2 2.3961 7.5314 1.5768 27.1527
LN-18 GDSC1; CTRP2 2.4561 3.1579 2.4561 23.906
Onda 11 GDSC1 2.4564 4.823 -0.7677 1.3497
D283 Med GDSC1; CTRP2 2.6949 3.4894 2.6948 22.315
KS-1 [Human Krukenberg tumour] GDSC1 2.9998 5.5344 -0.8086 1.0614
Daoy GDSC1; CTRP2 3.2133 6.6254 2.7786 20.4062
SF268 GDSC1; CTRP2 3.2273 5.9379 2.9984 19.5651
DBTRG-05MG GDSC1; CTRP2 3.2454 4.6852 2.3912 3.0377
LN-229 GDSC1; CTRP2 3.5344 4.2755 3.534 16.723
SNU-466 CTRP2 3.7122 4.9891 3.6916 15.6065
ONS-76 GDSC1; CTRP2 3.8237 4.8599 3.7577 8.9566
GB-1 GDSC1; CTRP2 3.842 5.8353 3.6946 15.1837
42-MG-BA GDSC1; CTRP2 3.8563 11.7016 1.2351 24.2296
SNU-738 CTRP2 3.88 5.0723 3.8603 14.4856
T98G GDSC1; CTRP2 3.9295 7.004 3.4181 15.9471
TM-31 CTRP2 4.3028 5.7789 4.2091 11.9257
SNB-75 GDSC1; CTRP2 4.3185 6.1405 4.1338 12.1477
AM-38 GDSC1; CTRP2 4.445 5.6717 4.1542 5.4501
CAS-1 GDSC1; CTRP2 4.4658 6.3476 4.2302 12.1657
SNU-1105 CTRP2 4.4921 5.2386 4.3794 4.3775
U-118MG GDSC1; CTRP2 4.5143 12.0458 1.6894 21.0466
SW1783 GDSC1; CTRP2 4.6053 11.5335 2.0244 19.6147
SW1088 GDSC1; CTRP2 4.6823 7.5432 3.4818 7.8231
Hs 683 GDSC1; CTRP2 4.7276 7.5952 4.0129 11.4753
U-87MG ATCC GDSC1; CTRP2 4.8589 6.9403 3.9377 5.3812
SNU-201 CTRP2 4.8804 7.3718 4.2678 10.0677
GaMG GDSC1; CTRP2 4.9159 6.7874 4.0636 4.6897
SF126 GDSC1; CTRP2 4.9584 7.6037 4.2431 9.9667
U-251MG GDSC1; CTRP2 4.9589 6.9609 4.5263 8.842
8-MG-BA GDSC1; CTRP2 4.969 6.7059 4.6417 8.3668
GOS-3 CTRP2 5.0341 6.2119 4.892 7.2353
A-172 GDSC1; CTRP2 5.0906 7.0749 4.6137 8.15
SNU-489 CTRP2 5.2142 6.104 5.1214 5.8574
M059K CTRP2 5.2283 6.3127 5.0683 6.0128
KNS-42 GDSC1; CTRP2 5.2505 9.3118 3.7096 11.4563
KG-1-C CTRP2 5.2598 5.9059 5.2216 5.3585
GMS-10 CTRP2 5.2667 6.4656 5.0525 5.9642
YH-13 GDSC1; CTRP2 5.3813 16.4643 0.272 23.6742
SNU-626 CTRP2 5.4216 7.2687 4.8587 6.3323
KNS-81 CTRP2 5.4292 6.6325 5.1549 5.1256
DK-MG GDSC1; CTRP2 5.4387 16.6122 0.2477 23.6228
YKG-1 GDSC1; CTRP2 5.4464 9.5855 3.7537 10.8427
SF295 GDSC1; CTRP2 5.5921 8.3297 4.5059 7.3959
KALS-1 GDSC1; CTRP2 6.03 10.6236 3.0275 7.2253
NMC-G1 GDSC1; CTRP2 6.6641 8.9333 5.0781 3.01
CCF-STTG1 CTRP2 7.0878 17.9611 0.9317 18.2976
Becker GDSC1; CTRP2 7.2073 15.3549 2.3192 13.2393
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 1.16 5.2612 -1.7109 10.0061
TGBC1TKB GDSC1 1.6363 3.1609 -0.4804 0.8218
TGBC24TKB GDSC1 2.3466 4.4746 -0.6806 1.0634
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC1; CTRP2 -0.4219 1.4409 -0.4227 43.082
EN GDSC1; CTRP2 1.968 4.3953 1.9141 27.3388
JHUEM-2 CTRP2 1.9755 3.4062 1.973 27.1159
MFE-280 GDSC1 2.2434 5.549 -1.1725 3.876
JHUEM-7 CTRP2 2.6103 3.1303 2.6103 22.8783
JHUEM-1 CTRP2 2.7593 4.006 2.7558 21.8974
HEC-6 CTRP2 2.8876 3.9629 2.8861 21.0361
RL95-2 GDSC1; CTRP2 3.0848 3.8793 3.0816 13.9987
HEC-1-B CTRP2 3.1218 5.3815 2.8453 14.7755
HEC-151 CTRP2 3.4559 4.3443 3.4403 11.3941
HEC-265 CTRP2 3.5004 4.578 3.495 16.9667
MFE-296 GDSC1; CTRP2 3.5029 5.8769 3.3147 17.5859
MFE-319 GDSC1; CTRP2 3.6906 5.8582 3.5239 16.2601
HEC-59 CTRP2 3.7112 5.4372 3.6345 15.8056
HEC-1-A CTRP2 3.9303 5.513 3.8576 14.3326
JHUEM-3 CTRP2 4.0557 6.2194 3.8238 14.0668
KLE GDSC1; CTRP2 4.2284 8.5668 3.0708 16.4954
ESS-1 GDSC1; CTRP2 4.4835 6.3304 4.2551 11.2114
HEC-251 CTRP2 4.7379 6.9049 4.3174 10.2532
HEC-108 CTRP2 4.8007 5.8839 4.7274 8.5389
HEC-50B CTRP2 5.0423 7.6176 4.3209 9.4434
EFE-184 CTRP2 5.2028 7.2841 4.0536 4.1449
Ishikawa (Heraklio) 02 ER- CTRP2 4.845 5.6893 4.8125 8.1009
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-195 GDSC1 1.3205 3.5112 -0.7854 3.0289
A-498 GDSC1 1.5777 3.4703 -0.6318 1.6593
HA7-RCC GDSC1 1.5882 3.6004 -0.6808 1.9258
RXF 393L GDSC1 1.641 3.9587 -0.8061 2.5988
LB1047-RCC GDSC1 1.656 5.0802 -1.2995 5.852
SW13 GDSC1 1.6602 3.6985 -0.6859 1.8527
NCC021 GDSC1 1.693 5.0051 -1.2426 5.3809
BB65-RCC GDSC1 1.8396 3.7713 -0.6298 1.3261
KTCTL-13 GDSC1 1.8895 3.9739 -0.6882 1.5685
SW156 GDSC1 1.9089 4.3217 -0.8223 2.2861
KTCTL-21 GDSC1 1.9663 4.8179 -1.0041 3.2936
KTCTL-140 GDSC1 2.0003 4.2573 -0.7509 1.7658
KTCTL-1M GDSC1 2.0685 4.5711 -0.847 2.2044
LB2241-RCC GDSC1 2.1067 4.168 -0.6662 1.2215
LB996-RCC GDSC1 2.1744 5.0201 -0.982 2.8311
SN12C GDSC1 2.2246 3.8707 -0.5049 0.4901
KTCTL-26A GDSC1 2.2429 4.6913 -0.8124 1.7965
A-704 GDSC1 2.356 3.8271 -0.4402 0.257
TK-10 GDSC1 2.6578 5.121 -0.7955 1.2871
TUHR10TKB CTRP2 2.8483 5.2856 2.7304 21.6957
UO-31 GDSC1; CTRP2 3.2762 4.6916 3.2589 18.5001
TUHR4TKB CTRP2 3.4723 4.6067 3.4653 17.1592
SNU-1272 CTRP2 3.8222 5.354 3.7669 14.9924
KMRC-3 CTRP2 3.9704 6.1573 3.7492 14.5948
BFTC-909 GDSC1; CTRP2 4.1042 5.7446 4.0006 13.2829
VMRC-RCW GDSC1; CTRP2 4.5026 5.8406 4.1374 5.3631
769-P GDSC1; CTRP2 4.596 9.6273 2.3693 12.9639
KMRC-20 GDSC1; CTRP2 4.6139 6.5128 4.3342 10.537
786-O GDSC1; CTRP2 4.9705 7.3992 4.3475 9.5186
RCC10RGB GDSC1; CTRP2 4.9714 6.7735 4.617 8.4557
KMRC-2 CTRP2 5.0653 7.2637 4.5044 8.6497
KMRC-1 GDSC1; CTRP2 5.1448 6.8215 4.7789 7.357
ACHN GDSC1; CTRP2 5.184 7.0005 4.7422 7.3979
VMRC-RCZ GDSC1; CTRP2 5.3676 8.9411 3.9995 9.9958
CAL-54 GDSC1; CTRP2 5.4464 8.7667 4.1576 9.1651
Caki-2 CTRP2 5.5671 8.0397 4.6256 6.9539
OS-RC-2 GDSC1; CTRP2 5.5725 9.3214 3.3285 6.6993
Caki-1 GDSC1; CTRP2 5.6041 6.5544 5.3689 3.8221
TUHR14TKB CTRP2 7.4166 13.8062 3.2392 9.323
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW48 GDSC1; CTRP2 -1.5046 -0.6602 -1.5046 46.7442
GP5d GDSC1 -0.3842 0.3887 -0.5514 6.3979
GP2d CTRP2 0.8138 2.7709 0.8088 34.8633
SNU-81 GDSC1 1.3152 3.2072 -0.6548 2.1921
SNU-1040 GDSC1 1.5501 3.1284 -0.506 1.0273
SNU-175 GDSC1; CTRP2 1.7513 4.128 1.7111 28.7361
SW1116 GDSC1 1.7705 3.2811 -0.4693 0.6614
CaR-1 GDSC1 1.9399 4.7561 -0.9914 3.2584
KM12 GDSC1; CTRP2 1.9538 3.7658 1.9159 22.1964
NCI-H716 GDSC1; CTRP2 2.0109 4.0905 1.9845 26.9602
COLO 320HSR GDSC1 2.1559 4.1698 -0.6453 1.0792
COLO 320 CTRP2 2.1914 3.7986 2.1839 25.6941
SW626 GDSC1 2.2166 4.4488 -0.7276 1.4012
HCC2998 GDSC1 2.2845 4.1273 -0.5753 0.6931
LS411N GDSC1; CTRP2 2.5074 4.7839 2.3423 18.7209
C2BBe1 GDSC1; CTRP2 2.5674 5.21 2.4407 23.597
SW948 GDSC1; CTRP2 2.586 3.151 2.586 23.0404
HCT 15 GDSC1; CTRP2 2.5977 3.1297 2.5977 22.9625
LS1034 GDSC1; CTRP2 2.6862 4.4045 2.6652 22.4433
SNU-407 GDSC1; CTRP2 2.691 4.2035 2.6473 16.9564
SNU-1033 CTRP2 2.7198 6.6147 2.2458 23.817
SNU-C1 GDSC1; CTRP2 2.7345 4.1848 2.7258 22.0803
NCI-H747 GDSC1; CTRP2 2.7383 7.0481 2.1199 24.2139
SW1463 GDSC1; CTRP2 2.7457 4.3736 2.7287 22.0332
HT-55 GDSC1; CTRP2 2.7648 4.3205 2.7103 16.4692
T84 GDSC1; CTRP2 2.7889 4.7766 2.7407 21.8512
LoVo GDSC1; CTRP2 2.8166 4.3499 2.6209 10.5383
HT115 GDSC1; CTRP2 2.8172 3.7965 2.8166 21.5021
SW837 GDSC1 2.8813 4.8993 -0.6229 0.5059
SNU-C2B GDSC1 2.9167 5.9268 -0.9965 1.9646
LS180 GDSC1; CTRP2 2.9224 4.092 2.9194 20.809
SK-CO-1 CTRP2 2.9569 3.8327 2.9527 14.9147
CCK-81 GDSC1; CTRP2 3.1824 4.4924 3.1321 13.4734
SW620 GDSC1; CTRP2 3.27 5.1603 3.0751 13.4001
NCI-H508 CTRP2 3.3239 4.6783 3.2526 12.5421
COLO205 GDSC1; CTRP2 3.3242 4.1044 3.3186 12.2984
SNU-61 GDSC1; CTRP2 3.3302 5.544 3.0168 13.4407
COLO201 CTRP2 3.3469 4.9634 2.3304 3.142
SNU-C2A CTRP2 3.3885 6.0617 2.8849 13.8008
SNU-C5 GDSC1; CTRP2 3.4725 5.917 3.0312 12.9499
DLD-1 CTRP2 3.5901 4.1507 3.59 16.3513
LS513 GDSC1; CTRP2 3.6198 4.9339 3.5184 10.5456
CL-11 GDSC1; CTRP2 3.6441 6.1657 3.1116 12.1136
RKO GDSC1; CTRP2 3.6654 5.2091 3.4915 10.5016
LS123 GDSC1; CTRP2 3.7207 5.3629 3.5017 10.2867
CW-2 GDSC1; CTRP2 3.7444 5.0906 3.7163 15.4177
OUMS-23 CTRP2 3.8097 5.2146 3.7721 15.0149
HCT 116 GDSC1; CTRP2 3.8173 5.0135 3.7994 14.8972
HCT 8 CTRP2 3.8292 5.2088 3.7934 14.8787
SNU-C4 CTRP2 3.851 4.4464 3.8508 14.6132
COLO 678 GDSC1; CTRP2 3.8514 7.2809 3.2282 16.8891
MDST8 GDSC1; CTRP2 4.1489 5.582 3.8816 7.4426
HT-29 GDSC1; CTRP2 4.1627 6.4 3.8838 13.5283
SW1417 GDSC1; CTRP2 4.2212 6.0852 4.0434 12.7695
RCM-1 [Human ESC] GDSC1; CTRP2 4.2516 6.2578 4.0257 12.7426
SNU-503 CTRP2 4.6595 6.5406 4.3734 10.2587
HCC-56 CTRP2 5.1434 6.3737 4.9549 6.6831
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 2.6935 4.2824 -0.4761 0.2258
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2 CTRP2 -0.9683 0.4399 -0.9707 33.4689
Li-7 CTRP2 0.072 10.6499 -2.1254 43.3704
Hep-G2/C3A GDSC1 0.6587 2.0808 -0.5273 2.6122
SNU-878 CTRP2 1.3384 6.6226 0.7398 33.2507
JHH-7 GDSC1 1.8463 4.145 -0.7796 2.129
SNU-398 GDSC1; CTRP2 2.2344 4.0962 2.2157 25.4454
Huh-7 GDSC1 2.2426 3.8523 -0.4913 0.4387
HLE GDSC1 2.2669 4.6728 -0.7938 1.6734
JHH-5 CTRP2 2.5762 3.9019 2.5723 23.1185
HLF CTRP2 2.9752 4.4724 2.9603 20.4973
Hep 3B2.1-7 GDSC1; CTRP2 3.1565 4.9707 3.0037 14.0456
SNU-182 CTRP2 3.3442 4.6714 3.3305 18.0351
HuH-6 CTRP2 3.3808 5.7711 2.9891 13.3974
HuH-1 GDSC1; CTRP2 3.3833 5.8921 3.1804 18.4345
SNU-761 CTRP2 3.5457 6.0487 3.3163 17.4492
SNU-387 GDSC1; CTRP2 3.8285 7.4598 3.133 17.3165
SNU-886 CTRP2 4.0638 6.1529 3.8523 13.9386
PLC/PRF/5 CTRP2 4.0945 6.2723 3.8501 13.8544
JHH-4 GDSC1; CTRP2 4.1108 6.6235 3.7518 14.1712
SNU-475 GDSC1; CTRP2 4.132 6.1842 3.9176 13.4958
JHH-1 GDSC1; CTRP2 4.2215 5.2041 4.2065 12.1949
SNU-423 GDSC1; CTRP2 4.7561 6.8426 4.3616 10.0325
SK-HEP-1 GDSC1; CTRP2 4.9186 5.7663 4.879 7.6355
JHH-2 GDSC1; CTRP2 5.056 7.9807 4.1659 10.0362
SNU-449 GDSC1; CTRP2 5.2326 8.4519 4.1116 9.8394
JHH-6 GDSC1; CTRP2 5.8826 6.3598 5.7377 1.6397
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 212 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1703 GDSC1; CTRP2 -1.4252 6.9556 -2.3732 49.8213
SBC-3 GDSC1 0.6707 2.4394 -0.6883 3.7628
NCI-H847 GDSC1 0.7556 2.5069 -0.6651 3.3846
LC-2/ad GDSC1 1.0619 3.9196 -1.1333 6.0675
COR-L321 GDSC1 1.0742 2.782 -0.6003 2.2635
NCI-H1688 GDSC1 1.0808 3.1213 -0.7489 3.2572
NCI-H1048 GDSC1 1.091 2.8748 -0.6321 2.442
NCI-H187 GDSC1 1.1311 2.264 -0.353 0.7255
NCI-H2803 GDSC1 1.1504 2.7376 -0.5397 1.7455
COR-L303 GDSC1 1.2587 3.7454 -0.9274 4.1251
COR-L311 GDSC1 1.3063 3.4976 -0.7874 3.0695
NCI-H345 GDSC1 1.3173 2.137 -0.2303 0.1472
Lu-139 GDSC1 1.3411 5.8613 -1.8751 10.6548
EMC-BAC-1 GDSC1 1.3667 5.091 -1.4885 7.8684
NCI-H2227 GDSC1 1.3986 3.4648 -0.7218 2.4743
NCI-H2722 GDSC1 1.4127 3.5032 -0.7309 2.508
NCI-H524 GDSC1 1.4239 3.6667 -0.7964 2.91
NCI-H2369 GDSC1 1.4736 3.1745 -0.5604 1.4007
NCI-H513 GDSC1 1.4798 4.5063 -1.1428 5.1507
NCI-H748 GDSC1 1.5508 3.591 -0.6959 2.0701
RERF-LC-KJ GDSC1 1.5828 3.2664 -0.546 1.1918
NCI-H1304 GDSC1 1.5935 3.0768 -0.4664 0.7986
DMS 79 GDSC1 1.5999 4.0629 -0.8736 3.0952
NCI-H2347 GDSC1 1.6142 4.458 -1.041 4.1726
HCC33 GDSC1 1.615 3.4497 -0.6052 1.4642
NCI-H64 GDSC1 1.6291 2.9511 -0.4037 0.5129
NCI-H596 GDSC1 1.6553 7.3183 -2.3613 13.0051
ABC-1 GDSC1 1.7123 4.2905 -0.9117 3.143
NCI-H1436 GDSC1 1.7137 3.5111 -0.5836 1.2344
NCI-H2135 GDSC1 1.7594 3.0774 -0.3982 0.411
NCI-H1770 GDSC1 1.7636 3.2542 -0.462 0.638
NCI-H209 GDSC1 1.7643 4.0157 -0.7666 2.1712
NCI-H1666 GDSC1; CTRP2 1.7864 3.1523 1.7799 23.2779
NCI-H1836 GDSC1 1.7865 3.2164 -0.4385 0.5328
SBC-1 GDSC1 1.8013 3.5267 -0.5504 0.9834
Ms-1 GDSC1 1.8423 3.8206 -0.6484 1.4174
A-427 GDSC1 1.8436 4.5597 -0.9579 3.2103
NCI-H720 GDSC1 1.8483 3.0924 -0.3696 0.2816
NCI-H2818 GDSC1 1.8596 4.1037 -0.7559 1.9756
NCI-H211 GDSC1; CTRP2 1.8835 4.5318 1.8095 27.9696
NCI-H23 GDSC1; CTRP2 1.8896 3.0181 1.8893 27.681
Lu-165 GDSC1 1.8991 3.4335 -0.4736 0.5842
IST-SL1 GDSC1 1.9012 6.2881 -1.7075 8.0867
NCI-H2595 GDSC1 1.9124 4.2856 -0.8054 2.1839
UMC-11 GDSC1 1.9209 3.6622 -0.5509 0.8763
NCI-H2869 GDSC1 1.9266 6.6749 -1.8726 9.1312
Lu-134-A GDSC1 1.9292 4.8121 -1.0216 3.4653
CPC-N GDSC1 1.942 3.9628 -0.6593 1.3603
NCI-H2795 GDSC1 1.9818 4.597 -0.9013 2.6431
NCI-H3255 GDSC1 2.0035 4.1153 -0.692 1.4562
COR-L23 GDSC1 2.0053 3.5404 -0.4705 0.505
NCI-H2171 GDSC1; CTRP2 2.0153 3.5962 2.01 26.8602
COR-L88 GDSC1 2.0452 5.3295 -1.1848 4.3014
NCI-H1993 GDSC1 2.0455 4.0499 -0.6471 1.1927
PaCa-3 GDSC1 2.0584 4.0053 -0.624 1.0741
NCI-H1341 CTRP2 2.0586 3.6279 2.0532 26.5719
NCI-H2081 GDSC1; CTRP2 2.0609 3.7409 2.0526 26.5664
NCI-H2461 GDSC1 2.0839 3.7716 -0.5244 0.6437
NCI-H841 GDSC1; CTRP2 2.093 3.6316 2.088 26.3415
NCI-H1437 GDSC1 2.1083 4.0997 -0.6389 1.0944
NCI-H1975 GDSC1 2.1553 4.0086 -0.5839 0.82
COR-L51 CTRP2 2.1731 4.2505 2.1421 25.8954
NCI-H82 GDSC1 2.1894 3.6779 -0.4493 0.3446
NCI-H2591 GDSC1 2.1955 4.2844 -0.6725 1.1644
NCI-H2373 GDSC1 2.2216 3.956 -0.5373 0.599
EMC-BAC-2 GDSC1 2.2365 5.1275 -0.9957 2.8199
NCI-H1648 GDSC1 2.2393 4.6105 -0.7815 1.6427
NCI-H290 GDSC1 2.2793 3.875 -0.4855 0.4034
NCI-H3122 GDSC1 2.3163 4.3153 -0.6327 0.8898
NCI-H2141 GDSC1; CTRP2 2.3219 3.9097 2.3135 24.8278
RERF-LC-MS GDSC1; CTRP2 2.3273 4.3027 2.2989 24.8591
LK-2 GDSC1 2.3292 4.4735 -0.6876 1.1092
RERF-LC-Sq1 GDSC1 2.3326 4.9347 -0.8688 1.9837
NCI-H2126 CTRP2 2.3468 3.5804 2.0941 7.0453
NCI-H1876 GDSC1 2.3793 4.1097 -0.5315 0.4888
NCI-H2087 GDSC1; CTRP2 2.4423 4.7235 2.2854 19.1541
DV-90 CTRP2 2.49 3.3693 2.4899 23.68
NCI-H2122 GDSC1; CTRP2 2.497 3.163 2.4968 18.1832
NCI-H810 GDSC1; CTRP2 2.5251 3.082 2.5251 23.4459
NCI-H1568 GDSC1; CTRP2 2.5262 3.6917 2.5248 23.4432
NCI-H1781 GDSC1 2.5291 4.1342 -0.484 0.2953
NCI-H1573 GDSC1; CTRP2 2.5537 3.8871 2.534 17.8484
HCC44 GDSC1; CTRP2 2.5595 4.1643 2.5473 23.2576
LC-1/sq GDSC1 2.5858 4.6214 -0.637 0.7145
NCI-H510A GDSC1; CTRP2 2.6025 3.6498 2.6018 22.933
NCI-H2029 GDSC1; CTRP2 2.6125 3.9567 2.6081 22.8785
NCI-H1581 GDSC1; CTRP2 2.6169 3.7772 2.6153 22.8396
NCI-H1105 CTRP2 2.6416 4.3173 2.6242 22.7283
NCI-H2804 GDSC1 2.6567 4.739 -0.652 0.7218
HCC4006 CTRP2 2.6862 4.4623 2.6612 22.4566
EBC-1 GDSC1; CTRP2 2.7251 3.8843 2.7123 16.6005
MOR/CPR CTRP2 2.7388 3.386 2.7388 22.0221
NCI-H1694 GDSC1; CTRP2 2.7486 3.6054 2.7485 21.9573
SW1573 GDSC1 2.7516 4.9049 -0.6753 0.7424
NCI-H2170 GDSC1; CTRP2 2.7806 3.6989 2.7803 21.7448
LUDLU-1 CTRP2 2.7939 3.8538 2.7928 21.659
Lu-99 CTRP2 2.8095 3.9382 2.8076 21.5574
NCI-H1915 GDSC1; CTRP2 2.8293 4.5053 2.807 21.4942
NCI-H446 GDSC1; CTRP2 2.8389 4.4196 2.8224 21.411
Lu-99A GDSC1 2.8506 4.9009 -0.6351 0.5566
NCI-H1385 CTRP2 2.8697 4.2579 2.8615 21.1776
HCC1833 CTRP2 2.897 5.5683 2.7268 21.5548
NCI-H2731 GDSC1 2.9031 4.6036 -0.5117 0.2346
NCI-H322M GDSC1 2.9066 5.5104 -0.8385 1.2556
EPLC-272H GDSC1; CTRP2 2.9077 5.9485 2.4156 17.1606
HCC827 GDSC1; CTRP2 2.9162 5.0241 2.8453 21.0811
NCI-H1155 GDSC1; CTRP2 2.932 4.1077 2.9288 20.7456
PC-14 GDSC1; CTRP2 2.9421 4.1686 2.9378 20.6824
DMS 53 GDSC1; CTRP2 2.9581 4.1251 2.955 20.5716
NCI-H2110 GDSC1; CTRP2 2.9722 4.6064 2.9487 20.5462
NCI-H1734 GDSC1; CTRP2 2.982 4.0872 2.9797 20.4096
NCI-H1373 CTRP2 2.9823 4.4099 2.9301 14.9087
HCC1588 CTRP2 2.9928 5.4342 2.8586 20.7905
Calu-3 GDSC1; CTRP2 3.003 6.1 2.7099 21.2875
SHP-77 GDSC1; CTRP2 3.0088 4.1181 2.9912 14.5929
NCI-H1623 GDSC1; CTRP2 3.0199 5.4169 2.8913 20.5904
NCI-H2023 GDSC1; CTRP2 3.0331 4.7072 2.2093 4.4782
NCI-H2009 GDSC1; CTRP2 3.0342 5.5422 2.8816 20.5795
NCI-H661 GDSC1; CTRP2 3.0543 4.5265 3.039 19.9719
LC-1F CTRP2 3.0739 9.7333 1.3769 25.8473
LXF 289 GDSC1; CTRP2 3.0917 4.375 2.424 3.2106
NCI-H650 GDSC1; CTRP2 3.1491 4.4274 3.106 13.6848
Lu-135 GDSC1 3.16 4.9608 -0.5429 0.2236
HCC95 CTRP2 3.2087 4.6176 3.1935 40.6754
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 3.2126 4.5144 3.2028 18.8986
NCI-H2196 GDSC1; CTRP2 3.2648 6.6576 2.8237 20.0883
NCI-H1355 GDSC1; CTRP2 3.2839 5.9383 2.822 14.3708
NCI-H2228 GDSC1; CTRP2 3.2932 5.8396 3.0953 19.0161
A-549 GDSC1; CTRP2 3.3025 4.2166 3.3013 18.2708
IST-SL2 GDSC1 3.303 5.3165 -0.6138 0.319
NCI-H1435 GDSC1; CTRP2 3.3162 4.7531 2.4112 2.7863
NCI-H526 GDSC1; CTRP2 3.3426 4.0861 3.3423 18.0008
NCI-H358 GDSC1; CTRP2 3.3889 6.422 3.0351 18.9439
NCI-H2030 GDSC1; CTRP2 3.4014 4.4276 3.3981 17.6189
CAL-12T GDSC1; CTRP2 3.4071 6.049 3.1649 18.417
NCI-H1944 GDSC1; CTRP2 3.4089 4.9886 3.373 17.6789
NCI-H292 GDSC1; CTRP2 3.438 4.1041 3.4379 17.3648
Lu-65 GDSC1; CTRP2 3.4389 6.2218 3.1505 18.3729
NCI-H2405 GDSC1; CTRP2 3.4689 5.975 3.0046 13.0697
NCI-H1838 GDSC1; CTRP2 3.4751 5.793 3.3049 17.7067
NCI-H69 GDSC1; CTRP2 3.4929 4.9062 3.4689 17.0791
HCC2108 CTRP2 3.4949 5.4261 3.4031 17.2989
RERF-LC-A1 CTRP2 3.5179 5.0863 3.4777 16.9677
NCI-H1092 GDSC1; CTRP2 3.5272 6.0616 3.2926 17.5908
NCI-H2286 CTRP2 3.5406 7.1684 1.3862 7.6364
NCI-H520 GDSC1; CTRP2 3.5575 5.4056 3.4743 16.8519
SBC-5 GDSC1; CTRP2 3.5633 4.1143 3.5633 16.5292
Calu-6 GDSC1; CTRP2 3.5696 5.2346 3.3792 11.2489
VMRC-LCD CTRP2 3.5889 4.993 3.5621 16.4492
ChaGo-K-1 GDSC1; CTRP2 3.5945 5.4324 3.5095 16.6117
COLO 699 CTRP2 3.6314 5.5615 3.3356 11.2299
NCI-H1651 GDSC1; CTRP2 3.6344 5.6611 3.5081 16.4909
HCC78 GDSC1; CTRP2 3.6348 6.5577 2.9343 12.8858
NCI-H727 GDSC1; CTRP2 3.6424 5.3439 3.4232 10.8442
NCI-H1563 GDSC1; CTRP2 3.6473 4.2536 3.6472 15.9702
NCI-H522 GDSC1; CTRP2 3.6638 5.1718 3.6223 16.0005
DMS 114 GDSC1; CTRP2 3.6749 5.1277 3.6392 15.9063
LCLC-103H GDSC1; CTRP2 3.7462 5.4736 3.4909 10.2507
LCLC-97TM1 GDSC1; CTRP2 3.7618 5.0284 3.649 9.5773
NCI-H1693 GDSC1; CTRP2 3.776 6.2121 3.5211 16.0099
NCI-H460 GDSC1; CTRP2 3.8052 4.98 3.7892 14.9717
NCI-H1184 CTRP2 3.815 6.2935 3.2349 11.1085
COR-L105 GDSC1; CTRP2 3.8406 6.0953 3.6252 15.4371
HOP-92 GDSC1; CTRP2 3.8747 6.2547 3.616 15.3679
BEN GDSC1; CTRP2 3.9108 4.5838 3.9102 14.2164
NCI-H1650 GDSC1; CTRP2 3.9367 6.4523 3.6211 15.1651
NCI-H1869 GDSC1; CTRP2 3.9524 6.4483 3.6396 15.0506
EKVX GDSC1; CTRP2 3.9958 6.5834 3.6413 14.9171
NCI-H1755 GDSC1; CTRP2 4.0022 6.0432 3.5363 9.3078
DMS 454 CTRP2 4.0087 5.9106 3.8578 14.0864
NCI-H1395 CTRP2 4.0253 5.8321 3.8951 13.9025
HOP-62 GDSC1; CTRP2 4.0475 7.6334 3.2924 16.1034
Sq-1 CTRP2 4.0713 5.7794 3.7196 8.3415
COLO 668 GDSC1; CTRP2 4.1433 6.2277 3.9168 13.4647
NCI-H647 GDSC1; CTRP2 4.1677 6.1866 3.9558 13.2494
HCC15 GDSC1; CTRP2 4.1755 7.4046 3.5214 14.869
NCI-H2085 GDSC1; CTRP2 4.1925 8.4873 3.0704 16.5888
NCI-H2172 GDSC1; CTRP2 4.1966 5.5428 3.9476 7.0297
NCI-H441 GDSC1; CTRP2 4.2066 6.0851 2.3562 1.6408
HCC2279 CTRP2 4.2623 5.439 4.2252 11.9986
NCI-H322 CTRP2 4.2688 6.5267 3.9563 12.949
COR-L95 GDSC1; CTRP2 4.3089 5.7091 4.2303 11.8322
NCI-H889 CTRP2 4.3109 5.6211 4.249 11.7604
NCI-H1793 GDSC1; CTRP2 4.3225 5.9894 4.18 11.9684
SK-MES-1 GDSC1; CTRP2 4.3338 6.7317 3.9533 12.7739
NCI-H838 GDSC1; CTRP2 4.3777 5.7711 4.2922 11.398
HCC366 CTRP2 4.4156 7.3487 3.3339 9.1098
LK2 CTRP2 4.4213 5.5698 4.3764 10.966
RERF-LC-Ad2 CTRP2 4.5273 8.1164 3.5762 13.7273
DMS 273 GDSC1; CTRP2 4.5388 6.1014 4.3854 10.5692
HCC1195 CTRP2 4.5731 6.2908 4.3653 10.5399
SW1271 GDSC1; CTRP2 4.6352 7.2848 4.0523 11.5624
NCI-H1792 GDSC1; CTRP2 4.6358 7.0431 3.687 7.0138
LC-1/sq-SF CTRP2 4.683 6.2665 4.4926 9.7456
NCI-H1299 GDSC1; CTRP2 4.7144 6.3795 4.4894 9.6655
LOU-NH91 GDSC1; CTRP2 4.747 6.4832 4.4884 9.575
NCI-H2342 GDSC1; CTRP2 4.7496 7.0531 4.269 10.4088
HCC1438 CTRP2 4.771 5.9914 4.6689 8.8393
HCC2935 CTRP2 4.8261 6.8556 4.4304 9.5749
NCI-H2444 GDSC1; CTRP2 4.8387 6.6992 4.5059 9.2492
NCI-H2291 GDSC1; CTRP2 4.8781 7.0651 4.3981 9.5597
KNS-62 CTRP2 4.9316 7.4196 4.2988 9.8121
SK-LU-1 GDSC1; CTRP2 4.9326 7.4751 3.7347 6.1333
NCI-H1339 CTRP2 5.128 6.6669 4.8254 7.2211
T3M-10 CTRP2 5.2376 6.3559 5.0628 6.0072
IA-LM GDSC1; CTRP2 5.3859 8.8841 4.0443 9.7695
NCI-H196 GDSC1; CTRP2 5.4456 8.8756 4.1033 9.3924
Calu-1 CTRP2 5.6065 8.598 4.3865 7.8626
RERF-LC-Ad1 CTRP2 6.074 8.5731 4.8046 5.1545
NCI-H226 GDSC1; CTRP2 6.3825 9.8825 4.3993 6.2887
HCC1171 CTRP2 7.988 16.3905 2.3881 11.6983
Hs 888.Lu CTRP2 4.3665 8.2288 3.3629 14.9863
⏷ Show the Full List of 212 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 1.9795 3.8068 -0.5814 0.9567
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.3112 6.0217 -0.2062 39.5235
ES-2 GDSC1 1.6403 3.3345 -0.5468 1.1313
OVCAR-3 GDSC1 1.9922 3.4724 -0.4509 0.4483
A2780 GDSC1; CTRP2 2.3131 3.7086 2.2961 19.5563
OVK18 GDSC1; CTRP2 2.5136 3.7744 2.4999 18.1132
OVKATE GDSC1 2.5252 4.2439 -0.524 0.3966
Caov-3 GDSC1; CTRP2 2.7356 4.6151 2.6276 16.8772
COV434 CTRP2 2.7802 3.7647 2.7796 21.7487
IGROV-1 GDSC1; CTRP2 2.9375 4.4728 2.8721 15.2771
OC 314 GDSC1; CTRP2 2.9649 4.0691 2.9627 20.5235
TYK-nu GDSC1; CTRP2 3.0194 4.411 2.9697 14.6347
Caov-4 GDSC1 3.1046 4.905 -0.5434 0.2388
COV644 CTRP2 3.3653 6.7641 2.8966 19.524
OVSAHO CTRP2 3.4587 4.9664 3.3345 11.7815
OVCAR-5 GDSC1; CTRP2 3.4861 6.6105 3.0797 18.4924
ES2 CTRP2 3.607 5.7931 3.2226 11.7632
HEY A8 CTRP2 3.6121 4.9735 3.5001 10.641
SNU-119 CTRP2 3.6172 6.1617 3.3625 17.0651
SNU-840 CTRP2 3.6316 4.8789 3.5444 10.4072
SNU-8 CTRP2 3.6541 4.1361 3.6541 15.9246
DOV13 GDSC1; CTRP2 3.7756 5.7297 3.4267 10.4226
JHOM-1 CTRP2 3.8285 5.6903 3.7128 15.1614
MCAS CTRP2 3.8852 5.377 3.6751 9.0817
OV7 CTRP2 3.9257 5.7231 3.8114 14.5091
OVTOKO GDSC1; CTRP2 4.0334 5.5999 3.9531 13.6725
ONCO-DG-1 CTRP2 4.1459 5.4885 3.9148 7.3155
OVCAR-4 GDSC1; CTRP2 4.3037 5.7647 3.9681 6.6343
RMG-I GDSC1; CTRP2 4.3174 7.8797 2.9831 10.9009
JHOC-5 CTRP2 4.3955 5.4727 4.3627 11.0962
OAW42 GDSC1; CTRP2 4.4029 5.7778 4.3181 11.2278
TOV-112D GDSC1; CTRP2 4.483 6.6917 4.1284 11.6872
OV-90 GDSC1; CTRP2 4.6954 6.1868 4.5309 9.5683
OAW28 GDSC1; CTRP2 4.8594 6.8547 4.4659 9.3466
SK-OV-3 GDSC1; CTRP2 4.8825 6.0852 4.3836 3.3281
Kuramochi GDSC1; CTRP2 4.9014 9.2856 2.8034 10.3779
JHOS-2 GDSC1; CTRP2 4.9281 7.2657 4.3634 9.5647
EFO-27 GDSC1; CTRP2 4.9394 7.3632 4.3319 9.6606
OVCAR-8 GDSC1; CTRP2 4.9569 7.743 3.6215 6.5906
FU-OV-1 GDSC1; CTRP2 5.0246 6.5192 4.7734 7.7077
OV56 GDSC1; CTRP2 5.151 6.2387 5.0102 6.4543
TOV-21G GDSC1; CTRP2 5.2124 6.9652 4.7868 7.1474
COV362 CTRP2 5.2287 8.1529 4.2517 9.2729
EFO-21 GDSC1; CTRP2 5.3315 7.2869 4.7614 6.9474
OVISE GDSC1; CTRP2 5.3352 7.5634 4.0183 4.0536
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 0.5419 2.9226 0.5285 36.702
SYO-1 CTRP2 3.4667 5.1582 3.4144 17.35
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 3.9091 5.2303 3.8755 14.3392
Yamato-SS CTRP2 4.1407 5.9849 3.9828 13.2332
TE 441.T GDSC1; CTRP2 -1.3265 -0.3222 -1.3265 49.106
A-204 GDSC1; CTRP2 -0.4525 6.2178 -1.094 44.3437
G-402 GDSC1; CTRP2 -0.2748 7.5545 -1.3164 43.836
Rh30 GDSC1 1.4155 3.0987 -0.5574 1.4605
VA-ES-BJ GDSC1 1.5477 3.4339 -0.6315 1.6987
EW-8 GDSC1 1.9278 3.4892 -0.4827 0.5978
SW684 GDSC1 1.9397 3.1166 -0.3446 0.1882
MFH-ino GDSC1 2.1401 3.966 -0.5741 0.7929
Hs 633.T GDSC1 2.5059 3.8985 -0.4115 0.1588
SW872 GDSC1 2.5418 4.4867 -0.605 0.6325
TE 617.T CTRP2 2.5513 3.1263 2.5513 23.2714
G-401 GDSC1; CTRP2 2.6293 4.711 2.5791 22.9214
GCT GDSC1; CTRP2 2.6489 4.2725 2.6341 22.671
MES-SA GDSC1; CTRP2 2.7034 3.1058 2.7034 22.258
BT-16 CTRP2 3.0071 3.7611 3.007 20.2352
KYM-1 GDSC1; CTRP2 3.0441 4.2794 3.0387 20.0066
BT-12 CTRP2 3.05 3.8819 3.0497 19.9498
Tm87-16 CTRP2 3.0884 4.1912 3.0856 19.7024
TTC-709 CTRP2 3.1363 4.1544 3.1345 19.3802
Rh41 GDSC1; CTRP2 3.1604 3.8851 3.1603 19.2138
RD GDSC1; CTRP2 3.2737 5.5414 3.1416 18.913
RKN GDSC1; CTRP2 3.6346 4.9303 3.5355 10.431
Rh18 CTRP2 3.8063 5.303 3.6147 9.5687
SK-UT-1 GDSC1; CTRP2 4.0802 6.5158 3.7558 14.2452
HT-1080 GDSC1; CTRP2 4.4958 6.6475 4.1584 11.5373
Hs 729.T CTRP2 4.6695 7.1211 4.1569 11.0617
SW982 GDSC1; CTRP2 5.1023 6.4654 4.877 7.0946
SK-LMS-1 GDSC1; CTRP2 5.1604 7.2621 4.6015 8.0194
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 5.3936 7.6925 4.6305 7.3311
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1 1.6141 3.9262 -0.8063 2.6442
NCI-H28 GDSC1; CTRP2 2.7647 3.6969 2.7608 16.2856
NCI-H2052 GDSC1; CTRP2 4.3456 6.1389 4.1638 11.957
NCI-H2452 GDSC1; CTRP2 4.3788 7.0111 3.8947 12.8707
IST-Mes1 GDSC1; CTRP2 5.2114 8.1583 4.2326 9.3921
ACC-MESO-1 CTRP2 5.3851 6.9651 4.9625 6.0038
JL-1 CTRP2 6.0815 6.8854 5.6544 1.5688
MPP 89 GDSC1; CTRP2 7.0032 10.5938 4.5108 4.8136
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 2.2333 4.4346 -0.7145 1.3218
VCaP GDSC1; CTRP2 2.5877 3.1681 2.5877 23.0291
22Rv1 GDSC1; CTRP2 2.7571 4.879 2.5913 16.9431
LNCaP clone FGC GDSC1; CTRP2 4.234 6.0522 4.0666 12.647
DU145 GDSC1; CTRP2 5.0544 8.0408 4.136 10.1618
PaCa-3 CTRP2 5.5468 6.8396 5.1821 4.7153
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; CTRP2 1.5168 5.2988 1.2851 30.9353
YD-15 CTRP2 2.8359 3.399 2.8359 21.3757
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 1.7018 3.5151 -0.5908 1.2842
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-719 CTRP2 -1.5491 0.0977 -1.5492 50.589
NCC-StC-K140 CTRP2 0.3963 5.4315 0.0364 38.6198
HSC-39 GDSC1 1.2955 2.8663 -0.5201 1.4129
LMSU CTRP2 1.3041 8.9122 -0.1199 35.6498
Fu97 GDSC1; CTRP2 1.4363 4.0625 1.3868 30.8651
SCH GDSC1 1.4909 3.1119 -0.5267 1.1988
IM95 GDSC1; CTRP2 1.6064 2.9601 1.6055 29.5693
RERF-GC-1B GDSC1 1.8522 4.9794 -1.138 4.357
TMK-1 GDSC1 1.9262 4.0972 -0.7209 1.6975
SNU-601 CTRP2 2.0626 3.3311 2.0614 26.5315
GCIY GDSC1 2.1946 3.8657 -0.5148 0.5395
TGBC11TKB GDSC1 2.2436 4.0564 -0.5656 0.6854
SNU-16 GDSC1; CTRP2 2.2655 2.9606 2.2655 25.1754
23132/87 GDSC1; CTRP2 2.4488 3.5079 2.4483 23.956
ECC10 GDSC1; CTRP2 2.4537 3.4665 2.4533 23.9228
RF-48 GDSC1 2.4742 4.3744 -0.5906 0.6249
SNU-1 GDSC1; CTRP2 2.4874 3.9278 2.4817 23.7162
GSS CTRP2 2.6327 4.1852 2.5877 17.377
OCUM-1 GDSC1; CTRP2 2.6521 4.4602 2.5668 17.3875
MKN28 GDSC1 2.6724 5.4652 -0.9241 1.8744
HuG1-N CTRP2 2.6944 3.8604 2.6925 22.3243
SNU-620 CTRP2 2.7217 3.3241 2.7216 16.5792
KE-39 CTRP2 2.765 5.7946 2.5305 22.6601
AGS GDSC1; CTRP2 2.7826 3.6646 2.7824 21.7311
HGC-27 GDSC1; CTRP2 2.8204 3.7503 2.82 21.4803
NCI-N87 GDSC1; CTRP2 2.848 5.0351 2.7708 21.557
NUGC-3 GDSC1; CTRP2 3.368 5.7495 1.9575 5.0355
SNU-5 GDSC1; CTRP2 3.4051 4.5073 3.3999 17.6007
SNU-668 CTRP2 3.475 4.6465 3.4665 17.1462
NUGC-4 GDSC1; CTRP2 3.5301 4.788 3.5162 16.7972
GSU CTRP2 3.7809 4.229 3.7809 15.0799
MKN45 GDSC1; CTRP2 3.7846 5.7244 3.4385 10.3473
KATO III CTRP2 3.8512 7.3193 3.2129 16.9478
Hs 746.T GDSC1; CTRP2 3.86 5.7692 3.7296 15.0032
MKN74 CTRP2 3.8872 6.005 3.7009 15.0221
MKN1 GDSC1; CTRP2 3.9599 5.8705 3.8145 15.4191
SNU-216 CTRP2 3.9841 6.6409 3.6088 15.0729
MKN7 GDSC1; CTRP2 4.0699 6.8663 3.6202 14.7839
ECC12 CTRP2 4.405 5.2513 4.3943 10.9578
SH-10-TC CTRP2 5.2641 6.4861 5.0417 6.0127
SNU-1077 CTRP2 3.9246 8.36 2.3809 14.5065
SNG-M GDSC1; CTRP2 4.0347 5.3776 3.8365 7.9714
SNU-685 CTRP2 4.5785 5.7979 4.5046 10.0203
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -1.6358 5.6102 -2.2228 50.9493
CGTH-W-1 GDSC1; CTRP2 0.5091 10.102 -1.4404 40.9458
KMH-2 GDSC1 1.1782 3.6621 -0.9381 4.377
HTC-C3 GDSC1 1.3544 3.4094 -0.7216 2.5495
ASH-3 GDSC1 1.6041 3.81 -0.7616 2.3848
K5 GDSC1 1.8957 3.8144 -0.6214 1.2237
WRO GDSC1 1.9175 3.618 -0.5354 0.8135
IHH-4 GDSC1 2.1465 3.5605 -0.4238 0.2965
TT GDSC1; CTRP2 2.7375 3.7077 2.737 22.0325
CAL-62 GDSC1; CTRP2 3.4485 5.3665 3.3636 17.5841
B-CPAP GDSC1; CTRP2 3.4704 5.5001 3.363 17.5166
8505C GDSC1; CTRP2 3.6027 5.6556 3.4748 16.7075
8305C GDSC1; CTRP2 3.683 4.8005 3.6733 15.7647
FTC-238 CTRP2 3.966 5.2737 3.9308 13.9653
BHT-101 GDSC1; CTRP2 4.0539 5.0671 4.0418 13.3016
ML-1 [Human leukemia] GDSC1; CTRP2 5.2875 7.6574 4.5445 7.9357
FTC-133 GDSC1; CTRP2 5.8422 7.4227 5.1802 4.0426
TT2609-C02 GDSC1; CTRP2 6.3672 11.4278 3.6167 9.5784
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-15A GDSC1 1.2921 3.41 -0.7565 2.89
LB771-HNC GDSC1 1.3709 3.3538 -0.6885 2.3109
YD-10B CTRP2 1.4383 3.6522 1.4177 30.7551
Ca9-22 GDSC1 1.671 3.3794 -0.5507 1.1175
BB30-HNC GDSC1 1.6786 3.7728 -0.7078 1.9527
OSC-20 GDSC1 1.7065 3.6384 -0.6386 1.5292
PCI-38 GDSC1 1.7249 3.7251 -0.6652 1.6506
SAT [Human HNSCC] GDSC1 1.796 4.131 -0.7991 2.3153
BICR 10 GDSC1 1.7973 4.9252 -1.1451 4.5098
PCI-06A GDSC1 1.8483 4.2437 -0.8201 2.3619
KOSC-2 GDSC1 1.8827 4.9262 -1.0972 4.0326
SAS GDSC1 1.8858 4.176 -0.7729 2.0359
BB49-HNC GDSC1 1.9345 4.9322 -1.0712 3.7711
SCC-15 GDSC1 1.9735 4.0098 -0.6636 1.3474
KON GDSC1 1.9837 3.5954 -0.4995 0.6212
Detroit 562 GDSC1; CTRP2 2.0463 5.2753 1.7067 22.6755
OSC-19 GDSC1 2.0474 3.9891 -0.6224 1.0773
HO-1-N-1 GDSC1 2.0765 3.905 -0.5776 0.8575
JHU-011 GDSC1 2.1013 5.217 -1.1048 3.6947
PCI-30 GDSC1 2.1845 5.0717 -0.9986 2.9143
HO-1-u-1 GDSC1 2.1991 4.255 -0.6595 1.1029
DOK GDSC1 2.2423 4.5106 -0.7404 1.4362
NCI-H3118 GDSC1 2.2434 4.2917 -0.6545 1.0414
JHU-022 GDSC1 2.2916 4.5129 -0.7193 1.2865
SCC-25 GDSC1; CTRP2 2.4628 3.9751 2.4312 18.5404
BICR 18 CTRP2 2.4814 13.9434 -1.161 34.2749
HSC-2 GDSC1; CTRP2 2.5478 4.0821 2.5386 23.3256
CAL-27 GDSC1; CTRP2 2.5537 4.1679 2.5411 23.2979
BICR 22 GDSC1; CTRP2 2.5994 3.9964 2.5938 22.9698
PE/CA-PJ34 (clone C12) CTRP2 2.6566 3.1727 2.6566 22.5702
SKN-3 GDSC1 2.7413 4.807 -0.6435 0.6421
PCI-04B GDSC1 2.8031 5.0761 -0.7178 0.86
BICR 78 GDSC1 2.9136 4.714 -0.5458 0.3005
BHY GDSC1; CTRP2 3.1494 4.3007 3.1452 19.301
HSC-3 GDSC1; CTRP2 3.1688 4.8449 3.0484 13.8339
SNU-46 CTRP2 3.2351 4.9281 3.1959 18.8483
CAL-33 GDSC1; CTRP2 3.2856 4.6389 3.2718 18.4256
SCC-4 GDSC1; CTRP2 3.4509 4.939 3.4221 17.3752
SNU-1076 CTRP2 3.4715 4.8216 3.4532 17.2024
SNU-1214 CTRP2 3.4758 4.3573 3.4744 17.117
PE/CA-PJ15 GDSC1; CTRP2 3.6079 6.3083 3.3089 17.2882
HSC-4 GDSC1; CTRP2 3.6526 5.6672 3.3193 11.231
PE/CA-PJ49 CTRP2 3.7044 5.4462 3.6257 15.8581
YD-8 CTRP2 3.8894 6.2033 3.6473 15.2095
SNU-899 CTRP2 4.0954 5.8171 3.9748 13.4016
FaDu GDSC1; CTRP2 4.1444 5.7618 4.0407 13.0156
BICR 6 CTRP2 4.1521 6.119 3.9584 13.287
PE/CA-PJ41 (clone D2) CTRP2 4.276 6.9186 3.8211 13.439
BICR 16 CTRP2 4.4377 5.8144 4.348 11.0136
BICR 31 GDSC1; CTRP2 4.6048 7.9462 3.7313 12.9114
BICR 56 CTRP2 4.7698 10.4061 2.7277 16.533
SNU-1041 CTRP2 4.8508 7.8058 3.4992 7.3689
SNU-1066 CTRP2 5.169 7.0166 4.1601 3.7318
SCC-9 GDSC1; CTRP2 5.3322 7.2351 4.7861 6.8462
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW780 GDSC1 2.2724 4.0889 -0.566 0.6674
RT-112 GDSC1; CTRP2 2.4465 5.5087 1.2893 10.8299
JMSU-1 CTRP2 2.4588 3.6785 2.4571 23.8934
UM-UC-1 CTRP2 2.5921 5.1967 2.4698 23.4171
253J CTRP2 2.8015 3.6473 2.8014 21.605
5637 GDSC1; CTRP2 2.921 5.6587 2.7328 21.4582
253J-BV CTRP2 3.0722 4.6716 3.048 19.8824
RT-4 GDSC1; CTRP2 3.0729 4.6582 2.267 4.0796
639V GDSC1; CTRP2 3.162 4.864 3.0364 13.9023
UM-UC-3 GDSC1; CTRP2 3.2088 4.9451 3.0673 13.6293
CAL-29 GDSC1; CTRP2 3.3128 5.0367 3.266 18.3565
BFTC-905 GDSC1; CTRP2 3.3139 4.3388 3.3112 18.2
SCaBER CTRP2 3.4655 5.9428 3.2571 17.9072
U-BLC1 CTRP2 3.5214 12.7762 0.3988 27.684
HT-1376 GDSC1; CTRP2 3.5731 6.1605 3.0395 12.6196
VM-CUB-1 CTRP2 3.6151 5.3834 3.5401 16.4401
TCCSUP GDSC1; CTRP2 3.7095 6.1994 3.4523 16.4604
KMBC-2 CTRP2 3.8212 5.3133 3.7716 14.9794
647V GDSC1; CTRP2 3.937 5.7037 3.8278 14.4156
KU-19-19 GDSC1; CTRP2 3.9849 4.7485 3.983 13.7271
HT-1197 GDSC1; CTRP2 4.115 5.9092 3.9742 13.3431
BC-3C CTRP2 4.2129 6.6204 3.8632 13.4589
SW1710 GDSC1; CTRP2 4.5127 6.9433 3.6222 7.5962
T24 GDSC1; CTRP2 4.9964 7.7442 4.2168 9.977
J82 GDSC1; CTRP2 5.4004 9.4152 3.7962 10.7666
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SKG-IIIa GDSC1 1.2269 2.9766 -0.6021 2.0087
JEG-3 GDSC1 1.2615 3.0731 -0.6254 2.0974
Ca Ski GDSC1 1.2838 6.428 -2.1906 12.9475
SiHa GDSC1 1.3979 2.853 -0.4658 0.9939
C-4-I GDSC1 1.541 3.4363 -0.6358 1.7327
SW954 GDSC1 1.5826 3.5616 -0.6674 1.8559
DSH1 GDSC1 1.6499 3.4191 -0.5763 1.2696
OVCA420 GDSC1 1.65 3.4724 -0.5978 1.3815
SW756 GDSC1 1.6644 3.3783 -0.5533 1.1373
MS751 GDSC1 1.6823 3.7318 -0.6888 1.839
OVCA433 GDSC1 1.7354 4.6579 -1.061 4.0707
HEC-1 GDSC1 1.749 3.2256 -0.4573 0.6305
SiSo GDSC1 1.796 4.7857 -1.0836 4.105
OV17R GDSC1 1.8927 5.4354 -1.3198 5.4867
NEC8 GDSC1 1.9192 3.6817 -0.5591 0.9133
SW962 GDSC1 1.9485 3.6259 -0.5254 0.7474
DoTc2 4510 GDSC1 1.9871 4.3507 -0.7956 2.0264
JHOS-3 GDSC1 1.9895 4.1288 -0.7039 1.5325
HT-3 GDSC1 1.9988 5.1388 -1.1265 4.0112
PA-1 GDSC1 2.0271 3.6105 -0.4876 0.5499
SKN GDSC1 2.0704 4.5626 -0.8425 2.1764
JAR GDSC1 2.1253 3.4587 -0.396 0.2381
CAL-39 GDSC1 2.2007 4.0669 -0.587 0.7976
NT2-D1 GDSC1 2.2028 4.2685 -0.6631 1.1155
ACC-OV7 GDSC1 2.2166 5.0053 -0.9544 2.6092
PEO1 GDSC1 2.2842 4.9086 -0.8812 2.1102
NCC-IT GDSC1 2.3082 7.299 -1.9233 8.5791
ME-180 GDSC1 2.309 4.8305 -0.8377 1.8496
KGN GDSC1 2.4013 4.1638 -0.5425 0.5111
OMC-1 [Human cervical carcinoma] GDSC1 2.4274 4.5136 -0.6613 0.9177
UWB1.289 GDSC1 2.4679 4.9667 -0.8191 1.5799
LB831-BLC GDSC1 2.4711 4.118 -0.4997 0.356
BPH-1 GDSC1 2.4912 4.9928 -0.8189 1.5549
C-33 A GDSC1 2.5589 4.2893 -0.5275 0.3912
HeLa GDSC1; CTRP2 2.7375 3.1082 2.7375 22.0312
HEY GDSC1 2.9048 5.1019 -0.6868 0.6885
OVMIU GDSC1 3.835 6.2225 -0.7353 0.4048
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5657).
2 Preclinical activity of ABT-869, a multitargeted receptor tyrosine kinase inhibitor. Mol Cancer Ther. 2006 Apr;5(4):995-1006.