Details of the Drug

General Information of Drug (ID: DMRHQTU)

Drug Name

PSMA subunit vaccine

Synonyms

Recombinant soluble PSMA vaccine; RsPSMA vaccine; PSMA subunit vaccine (prostate cancer); PSMA recombinant soluble protein vaccine, CYTOGEN/Progenics; PSMA rs protein vaccine, CYTOGEN/Progenics; PSMA protein vaccine (prostate cancer), Progenics/CYTOGEN; PSMA purified protein vaccine (prostate cancer), Progenics/CYTOGEN; PSMA subunit vaccine (prostate cancer), Progenics/CYTOGEN; PSMA-based therapeutics, CYTOGEN/Progenics

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Phase 1	[1]
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Drug Type

Vaccine

Cross-matching ID

DrugBank ID: DB06361
TTD ID: D08JYV

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glutamate carboxypeptidase II (GCPII)	TT9G4N0	FOLH1_HUMAN	Not Available	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

ICD Disease Classification

02 Neoplasm

Disease Class

ICD-11: 2C82 Prostate cancer

The Studied Tissue

Prostate

The Studied Disease

Prostate cancer [ICD-11:2C82]

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Glutamate carboxypeptidase II (GCPII)	DTT	FOLH1	1.40E-09	2.08	2.21

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Clinical pipeline report, company report or official report of Alphavax.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1606).