Details of the Drug

General Information of Drug (ID: DMRIK2Y)

Drug Name

MC-02,479

Synonyms

RWJ-54428; (6R,7R)-7-[2-(2-Amino-5-chlorothiazol-4-yl)-2(Z)-(hydroxyimino)acetamido]-3-[3-(2-aminoethylsulfanylmethyl)pyridin-4-ylsulfanyl]-3-cephem-4-carboxylic acid methanesulfonate

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Discontinued in Phase 1	[1]

Structure

3D MOL

2D MOL

Cross-matching ID

PubChem CID: 9873517
TTD ID: D09ANC

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Penicillin binding protein (Bact PBP)	TTJP4SM	NOUNIPROTAC	Inhibitor	[2]

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009332)
2	RWJ-54428 (MC-02,479), a new cephalosporin with high affinity for penicillin-binding proteins, including PBP 2a, and stability to staphylococcal be... Antimicrob Agents Chemother. 2003 Feb;47(2):658-64.