Details of the Drug

General Information of Drug (ID: DMRJK3U)

Drug Name
Avotermin
Synonyms Juvista; RN-1001; SPD-538; TGF3, Renovo; RN-1, Renovo
Indication
Disease Entry ICD 11 Status REF
Sarcoidosis 4B20.5 Phase 3 [1]
Cross-matching ID
UNII
2Q1GS25JWN
DrugBank ID
DB11955
TTD ID
D0P9YQ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Transforming growth factor beta 3 (TGFB3) TTWOMY8 TGFB3_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00742443) Juvista in Scar Revision Surgery of Disfiguring Scars. U.S. National Institutes of Health.
2 Discovery and development of avotermin (recombinant human transforming growth factor beta 3): a new class of prophylactic therapeutic for the improvement of scarring. Wound Repair Regen. 2011 Sep;19 Suppl 1:s38-48.